We developed a software named Repeat Locator (RepLoc), which quantifies the sequence repetitiveness based on weighted k-mer coverage. The repetitiveness map (Rmap) generated by RepLoc can be used to determine all repetitive sequences in the genome. The potential applications of this method include: de novo repeat detection (both common repeats and segmental duplications), genome structure and genome mappability analysis, etc.

The workflow of RepLoc:


  • 2021-03-12: Cross-species Rmap comparison.
  • 2020-05-12: 6 marine microorganisms added.
  • 2020-03-10: Major updates.
  • 2019-05-25: The Rmap visualization modified.
  • 2019-01-19: Bigwig tracks added in JBrowse.
  • 2018-12-27: The website launched.
  • 2018-05-06: JBrowse pages constructed.
  • 2018-02-25: The analysis workflow built.
  • 2017-12-06: Main programs developed.
  • 2017-05-10: The project launched.


Cong Feng, Min Dai, Yongjing Liu, Ming Chen. (2021) Sequence repetitiveness quantification and de novo repeat detection by weighted k-mer coverage, Briefings in Bioinformatics, 22(3): bbaa086, https://doi.org/10.1093/bib/bbaa086

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