Landscape of cell-type-specific genetic variation of gene regulation.

Variant-level cell-type-specific genetic variations of gene regulation across 42 major cell types from 20 human tissues inferred from "An analytical framework for decoding cell-type-specific genetic variation of gene regulation".

Fibroblast (39)
Monocyte (27)
Gastrointestinal smooth muscle cell (26)
other 5 cell types
Granulocyte (104)
Conventional dendritic cell (103)
Monocyte (97)
other 6 cell types
Pit cell (187)
Monocyte (162)
Endothelial cell (153)
other 9 cell types
Enterocyte (57)
T cell (53)
Conventional dendritic cell (50)
other 9 cell types
T cell (68)
B cell (57)
Enterocyte (56)
other 3 cell types
Monocyte (262)
T cell (230)
Enterocyte (201)
other 6 cell types
Vascular smooth muscle cell (446)
Myofibroblast (390)
Monocyte (352)
other 6 cell types
NK cell (824)
Myeloid progenitor cell (774)
Plasmacytoid dendritic cell (773)
other 7 celltypes
T cell (154)
Conventional dendritic cell (151)
B cell (146)
other 6 celltypes
Granulocyte (117)
Monocyte (116)
Immune cell (106)
other 7 cell types
T cell (80)
Monocyte (74)
B cell (66)
other 6 cell types
Esophageal smooth muscle cell (973)
Monocyte (937)
Antigen-presenting Epithelial cell (924)
other 8 cell types
Monocyte (211)
T cell (205)
Granulocyte (204)
other 8 cell types
Ventricle cardiomyocyte (231)
Monocyte (210)
Fibroblast (194)
other 4 cell types
Fast skeletal muscle cell (125)
Conventional dendritic cell (121)
Monocyte (116)
other 8 cell types
Immune cell (95)
T cell (91)
B cell (88)
other 7 cell types
Monocyte (17)
Neuroendocrine cell (16)
Luminal cell (13)
other 3 cell types
T cell (117)
Granulocyte (114)
Monocyte (97)
other 3 cell types
Fibroblast (18)
Stromal cell (11)
Endothelial cell (9)
other 2 celltypes

Introduction

The hyperlinks point to the page where the information on identified cell-type-specific functional regulatory variants inferred from ab initio predictions of variant effects and the associated regulated genes based on standard eQTLs and cell cluster-ieQTLs is provided.

Data information
  • SpeciesHuman
  • Tissue19
  • Cell lineage8
  • Major cell type42
  • Functional regulatory variants5,439
  • Variant-gene links10,707


News
  • 2023-05.19
  • Database online.
  • 2022-06.26
  • More datasets added.
  • 2021-12.23
  • HUATUO database construction.

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