This figure is dynamically displayed, allowing users to customize the graphical parameters using VOSviewer control panel for further research. The interactions cover all secretion systems (T1SE-T10SE), with the majority originating from T3SE and T4SE, accounting for 1,202 and 379 interactions, respectively. The edges represent protein-protein interactions (PPIs), while the size of each node reflects the number of interactions associated with each protein.
These two bar charts respectively display the distribution of interaction pairs between effector proteins of secretion systems types 1-10 and human proteins interactions, as well as the distribution of bacterial and human proteins within each type of interaction pair.
Zhu Y, Liu L, Hu Y, Li S, Liu E, Hu Y, Zhang S, Chao H, Fang Q, Huan Y, Chen M. InTxDB: A curated database of experimentally validated interactions between Gram-negative bacterial effectors and human host proteins. Database, 2025.
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