Cell-type-specific genetic variations of gene regulation causally associated to complex traits and diseases.
Endothelial
Endothelial cell (664)
Neuron
Oligodendrocyte (34)
Neurocyte (14)
Secretory
Thyroid follicular cell (105)
Zona fasciculata cell (81)
Gastric chief cell (67)
other 3 cell types
Erythroid
Erythroid cell (123)
Immune
B cell (517)
Monocyte (400)
T cell (349)
other 10 cell types
Muscle
Esophageal smooth muscle cell (252)
Vascular smooth muscle cell (201)
Smooth muscle cell(general) (141)
other 4 cell types
Stromal
Myofibroblast (204)
Fibroblast (158)
Epithelial
Stromal cell (160)
Enterocyte (155)
Epithelial cell (142)
other 9 cell types

Introduction

The hyperlinks are directed to the relevant pages displaying the function mapping of disease-causal and trait-causal genetic variations to cell-type-specific genetic variations of gene regulation at single-base resolutions. The mapped variants that are considered most likely to contribute to phenotypic variations with a cell-type-specific manner, the fine mapping results (PIPs) of the GWAS loci, the related standard eQTLs or cell cluster-ieQTLs and the inferred candidate genes underlying the biological mechanisms of complex phenotypes can be found.

Data information
  • SpeciesHuman
  • Cell lineage8
  • Major cell type44
  • Mapped functional variants699
  • Candidate functional gene672

External Links