| Entry name | Protein name | Involved in ND | Subcellular location |
|---|---|---|---|
| BolA-like protein 1 (hBolA) | Mitochondrion | ||
| Filamin-binding LIM protein 1 (FBLP-1) (Migfilin) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) | Cell junction, focal adhesion | ||
| Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1) | |||
| DNA mismatch repair protein Mlh1 (MutL protein homolog 1) | Nucleus | ||
| Ceruloplasmin (EC 1.16.3.1) (Ferroxidase) | |||
| Apolipoprotein A-I (Apo-AI) (ApoA-I) (Apolipoprotein A1) [Cleaved into: Proapolipoprotein A-I (ProapoA-I); Truncated apolipoprotein A-I (Apolipoprotein A-I(1-242))] | Secreted. | ||
| Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase) | Nucleus | ||
| NADH-cytochrome b5 reductase 3 (B5R) (Cytochrome b5 reductase) (EC 1.6.2.2) (Diaphorase-1) [Cleaved into: NADH-cytochrome b5 reductase 3 membrane-bound form; NADH-cytochrome b5 reductase 3 soluble form] | Isoform 1: Endoplasmic reticulum membrane | ||
| 2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase) | Mitochondrion matrix | ||
| Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1) | Nucleus | ||
| Potassium voltage-gated channel subfamily A member 2 (NGK1) (Voltage-gated K(+) channel HuKIV) (Voltage-gated potassium channel HBK5) (Voltage-gated potassium channel subunit Kv1.2) | Cell membrane | ||
| B-cell lymphoma 6 protein (BCL-6) (B-cell lymphoma 5 protein) (BCL-5) (Protein LAZ-3) (Zinc finger and BTB domain-containing protein 27) (Zinc finger protein 51) | Nucleus | ||
| Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Neuroligin-3 (Gliotactin homolog) | autism spectrum disorder | Cell membrane | |
| Nucleolar protein 56 (Nucleolar protein 5A) | Nucleus, nucleolus | ||
| Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin) | progressive muscular atrophy | Cytoplasm | |
| Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13) | Nucleus. | ||
| Inward rectifier potassium channel 2 (Cardiac inward rectifier potassium channel) (Inward rectifier K(+) channel Kir2.1) (IRK-1) (hIRK1) (Potassium channel, inwardly rectifying subfamily J member 2) | Membrane | ||
| Glutamate receptor 3 (GluR-3) (AMPA-selective glutamate receptor 3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (GluA3) | |||
| 5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A) | Cell membrane | ||
| Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) | Cytoplasm | ||
| DENN domain-containing protein 4B | Golgi apparatus | ||
| Nitric oxide synthase, brain (EC 1.14.13.39) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Peptidyl-cysteine S-nitrosylase NOS1) (bNOS) | Cell membrane, sarcolemma | ||
| DNA polymerase epsilon subunit 3 (EC 2.7.7.7) (Arsenic-transactivated protein) (AsTP) (Chromatin accessibility complex 17 kDa protein) (CHRAC-17) (HuCHRAC17) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17) | Nucleus | ||
| Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1) (p38) | Cytoplasm, cytosol | ||
| Potassium voltage-gated channel subfamily A member 5 (HPCN1) (Voltage-gated potassium channel HK2) (Voltage-gated potassium channel subunit Kv1.5) | Cell membrane | ||
| Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46) | Lysosome membrane | ||
| Neuroligin-4, X-linked (Neuroligin X) (HNLX) | autism spectrum disorder | Cell membrane | |
| Glutamate receptor ionotropic, kainate 1 (GluK1) (Excitatory amino acid receptor 3) (EAA3) (Glutamate receptor 5) (GluR-5) (GluR5) | Cell membrane | ||
| Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor) | Nucleus | ||
| Coiled-coil domain-containing protein 173 | |||
| RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3) | Nucleus | ||
| Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1) | autism spectrum disorder | ||
| Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1) | Isoform BIN1: Nucleus | ||
| Cullin-4B (CUL-4B) | Nucleus | ||
| Potassium voltage-gated channel subfamily A member 1 (Voltage-gated K(+) channel HuKI) (Voltage-gated potassium channel HBK1) (Voltage-gated potassium channel subunit Kv1.1) | episodic ataxia | Cell membrane | |
| Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114) | Nucleus | ||
| Insulin-induced gene 2 protein (INSIG-2) | Endoplasmic reticulum membrane | ||
| Caveolin-3 (M-caveolin) | progressive muscular atrophy | Golgi apparatus membrane | |
| Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3) | agenesis of the corpus callosum with peripheral neuropathy | Basolateral cell membrane | |
| Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55) | Endoplasmic reticulum | ||
| Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7) | Nucleus | ||
| Telethonin (Titin cap protein) | Cytoplasm, myofibril, sarcomere | ||
| Multiple PDZ domain protein (Multi-PDZ domain protein 1) | |||
| Heterogeneous nuclear ribonucleoprotein M (hnRNP M) | Nucleus, nucleolus | ||
| F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4) | Isoform 1: Nucleus, nucleoplasm | ||
| Annexin A1 (Annexin I) (Annexin-1) (Calpactin II) (Calpactin-2) (Chromobindin-9) (Lipocortin I) (Phospholipase A2 inhibitory protein) (p35) | Nucleus | ||
| Proteasome adapter and scaffold protein ECM29 (Ecm29 proteasome adapter and scaffold) (Proteasome-associated protein ECM29 homolog) | Endoplasmic reticulum | ||
| Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74) | Mitochondrion | ||
| SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1) | Cytoplasm | ||
| Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta) | |||
| Pogo transposable element with ZNF domain (Suppressor of hairy wing homolog 5) (Zinc finger protein 280E) (Zinc finger protein 635) | autism spectrum disorder | ||
| rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (34 kDa nucleolar scleroderma antigen) (Histone-glutamine methyltransferase) | Nucleus, nucleolus | ||
| Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen) | Nucleus | ||
| Cullin-2 (CUL-2) | |||
| Ubiquitin-conjugating enzyme E2 variant 2 (DDVit 1) (Enterocyte differentiation-associated factor 1) (EDAF-1) (Enterocyte differentiation-promoting factor 1) (EDPF-1) (MMS2 homolog) (Vitamin D3-inducible protein) | |||
| Ubiquitin-conjugating enzyme E2 K (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase) | Cytoplasm | ||
| Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr) | Mitochondrion matrix | ||
| 5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein) | Nucleus, nucleolus | ||
| Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)] | Cytoplasm. | ||
| Protein ELYS (Embryonic large molecule derived from yolk sac) (Protein MEL-28) (Putative AT-hook-containing transcription factor 1) | Cytoplasm | ||
| Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase) | |||
| Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2) | Mitochondrion outer membrane | ||
| Glutamine-rich protein 1 | |||
| Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4) | |||
| Zinc finger CCCH domain-containing protein 11A | |||
| Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3) | Cell membrane | ||
| Nuclear migration protein nudC (Nuclear distribution protein C homolog) | |||
| Transcriptional enhancer factor TEF-5 (DTEF-1) (TEA domain family member 3) (TEAD-3) | Nucleus. | ||
| Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) (Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator) | Endoplasmic reticulum membrane | ||
| Gastrin-releasing peptide (GRP) [Cleaved into: Neuromedin-C (GRP-10)] | Secreted | ||
| Centrosome-associated protein CEP250 (250 kDa centrosomal protein) (Cep250) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Centrosomal protein 2) | Cytoplasm, perinuclear region | ||
| Lamin-B receptor (Integral nuclear envelope inner membrane protein) (LMN2R) | Nucleus inner membrane | ||
| Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1) | Nucleus | ||
| Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PP-T) (PPT) | Alzheimer disease | Nucleus | |
| GPI inositol-deacylase (EC 3.1.-.-) (Post-GPI attachment to proteins factor 1) (hPGAP1) | Endoplasmic reticulum membrane | ||
| COMM domain-containing protein 6 | Nucleus | ||
| Synaptotagmin-12 (Synaptotagmin XII) (SytXII) | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane | ||
| Vacuolar protein sorting-associated protein 26B (Vesicle protein sorting 26B) | Cytoplasm | ||
| Histone-lysine N-methyltransferase EZH1 (EC 2.1.1.43) (ENX-2) (Enhancer of zeste homolog 1) | Nucleus | ||
| Heat shock transcription factor, Y-linked (Heat shock transcription factor 2-like protein) (HSF2-like) | Nucleus | ||
| m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS) | |||
| Jupiter microtubule associated homolog 1 (Androgen-regulated protein 2) (Hematological and neurological expressed 1 protein) [Cleaved into: Jupiter microtubule associated homolog 1, N-terminally processed] | Nucleus | ||
| Scavenger receptor class A member 3 (Cellular stress response gene protein) | Endoplasmic reticulum membrane | ||
| Prolyl endopeptidase (PE) (EC 3.4.21.26) (Post-proline cleaving enzyme) | Cytoplasm. | ||
| Phenylalanine--tRNA ligase, mitochondrial (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase) (PheRS) | Mitochondrion matrix | ||
| Elongation factor 1-beta (EF-1-beta) | |||
| Nuclear protein localization protein 4 homolog (Protein NPL4) | Cytoplasm, cytosol | ||
| Oxysterol-binding protein-related protein 3 (ORP-3) (OSBP-related protein 3) | Endoplasmic reticulum membrane | ||
| Nuclear protein MDM1 | Nucleus | ||
| Netrin-4 (Beta-netrin) (Hepar-derived netrin-like protein) | Secreted, extracellular space, extracellular matrix, basement membrane | ||
| Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase) | Cytoplasm, cytoskeleton | ||
| RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha) | Cytoplasm | ||
| Cytochrome b5 type B (Cytochrome b5 outer mitochondrial membrane isoform) | Mitochondrion outer membrane | ||
| Proteasome subunit beta type-8 (EC 3.4.25.1) (Low molecular mass protein 7) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13) (Proteasome component C13) (Proteasome subunit beta-5i) (Really interesting new gene 10 protein) | Cytoplasm | ||
| Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1) | Nucleus. | ||
| Protein NipSnap homolog 1 (NipSnap1) | |||
| Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2) | Cytoplasm | ||
| Keratin-associated protein 15-1 | |||
| AP-4 complex subunit mu-1 (AP-4 adaptor complex mu subunit) (Adaptor-related protein complex 4 subunit mu-1) (Mu subunit of AP-4) (Mu-adaptin-related protein 2) (mu-ARP2) (Mu4-adaptin) (mu4) | Golgi apparatus, trans-Golgi network membrane | ||
| Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (A-SCS) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA) | Mitochondrion | ||
| Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (NFATx) (T-cell transcription factor NFAT4) (NF-AT4) | Cytoplasm | ||
| Uncharacterized protein C9orf43 | |||
| Nucleosome assembly protein 1-like 4 (Nucleosome assembly protein 2) (NAP-2) | Nucleus | ||
| Oxidoreductase HTATIP2 (EC 1.1.1.-) (30 kDa HIV-1 TAT-interacting protein) (HIV-1 TAT-interactive protein 2) | Cytoplasm | ||
| Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM-protein 1) (SLIM) (SLIM-1) | progressive muscular atrophy | Isoform 1: Cytoplasm. | |
| Fructose-bisphosphate aldolase A (EC 4.1.2.13) (Lung cancer antigen NY-LU-1) (Muscle-type aldolase) | |||
| Cullin-1 (CUL-1) | |||
| FAS-associated factor 2 (Protein ETEA) (UBX domain-containing protein 3B) (UBX domain-containing protein 8) | Cytoplasm | ||
| X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6) | Nucleus | ||
| M-phase phosphoprotein 8 (Two hybrid-associated protein 3 with RanBPM) (Twa3) | Nucleus | ||
| Ribonuclease P protein subunit p20 (RNaseP protein p20) (EC 3.1.26.5) (Ribonucleases P/MRP protein subunit POP7 homolog) (hPOP7) | Nucleus, nucleolus | ||
| Death effector domain-containing protein (DEDPro1) (Death effector domain-containing testicular molecule) (FLDED-1) | Cytoplasm | ||
| Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC) | Cytoplasm, cytoskeleton | ||
| Unconventional myosin-VI (Unconventional myosin-6) | Golgi apparatus, trans-Golgi network membrane | ||
| Cytosolic Fe-S cluster assembly factor NUBP2 (Nucleotide-binding protein 2) (NBP 2) | Nucleus | ||
| Mitochondrial-processing peptidase subunit beta (EC 3.4.24.64) (Beta-MPP) (P-52) | autosomal recessive cerebellar ataxia | Mitochondrion matrix | |
| Bone morphogenetic protein 4 (BMP-4) (Bone morphogenetic protein 2B) (BMP-2B) | Secreted, extracellular space, extracellular matrix. | ||
| Metabotropic glutamate receptor 4 (mGluR4) | Cell membrane | ||
| Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit] | |||
| Lysosomal thioesterase PPT2 (PPT-2) (EC 3.1.2.-) (S-thioesterase G14) | Lysosome | ||
| Hemogen (Erythroid differentiation-associated gene protein) (EDAG-1) (Hemopoietic gene protein) (Negative differentiation regulator protein) | Nucleus | ||
| Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-) | Cytoplasm | ||
| DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194) | Nucleus, nucleolus | ||
| Gamma-sarcoglycan (Gamma-SG) (35 kDa dystrophin-associated glycoprotein) (35DAG) | Cell membrane, sarcolemma | ||
| Protein SCO1 homolog, mitochondrial | Mitochondrion | ||
| DNA-directed RNA polymerase III subunit RPC7 (RNA polymerase III subunit C7) (DNA-directed RNA polymerase III subunit G) (RNA polymerase III 32 kDa apha subunit) (RPC32-alpha) (RNA polymerase III 32 kDa subunit) (RPC32) | Nucleus | ||
| Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1) | |||
| Trafficking protein particle complex subunit 2 (Sedlin) | Cytoplasm, perinuclear region | ||
| Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210) | Isoform 1: Endoplasmic reticulum-Golgi intermediate compartment | ||
| EKC/KEOPS complex subunit LAGE3 (L antigen family member 3) (Protein ESO-3) (Protein ITBA2) | Cytoplasm | ||
| DNA replication licensing factor MCM5 (EC 3.6.4.12) (CDC46 homolog) (P1-CDC46) | Nucleus | ||
| 14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1) | |||
| Renin receptor (ATPase H(+)-transporting lysosomal accessory protein 2) (ATPase H(+)-transporting lysosomal-interacting protein 2) (ER-localized type I transmembrane adaptor) (Embryonic liver differentiation factor 10) (N14F) (Renin/prorenin receptor) (Vacuolar ATP synthase membrane sector-associated protein M8-9) (ATP6M8-9) (V-ATPase M8.9 subunit) | Membrane | ||
| U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm) | Cytoplasm | ||
| Zinc finger protein-like 1 (Zinc finger protein MCG4) | Golgi apparatus, cis-Golgi network membrane | ||
| ATP synthase-coupling factor 6, mitochondrial (ATPase subunit F6) (ATP synthase peripheral stalk subunit F6) | Mitochondrion | ||
| MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1) | Isoform 2: Cytoplasm. | ||
| 85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9) | Parkinson disease | ||
| Neugrin (Mesenchymal stem cell protein DSC92) (Neurite outgrowth-associated protein) (Spinal cord-derived protein FI58G) | Nucleus | ||
| RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7) | |||
| Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1) | |||
| Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin-1) | spastic ataxia | Isoform 1: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane | |
| Acetylcholinesterase (AChE) (EC 3.1.1.7) | Cell junction, synapse | ||
| Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G) | Cytoplasm, cytoskeleton | ||
| Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)] | Nucleus | ||
| Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8) | Cytoplasm, cytoskeleton | ||
| Peptidyl-prolyl cis-trans isomerase FKBP2 (PPIase FKBP2) (EC 5.2.1.8) (13 kDa FK506-binding protein) (13 kDa FKBP) (FKBP-13) (FK506-binding protein 2) (FKBP-2) (Immunophilin FKBP13) (Rotamase) | Endoplasmic reticulum membrane | ||
| WD repeat-containing protein 81 | Early endosome membrane | ||
| Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (hOTU1) (Ubiquitin-specific-processing protease OTUB1) | Cytoplasm | ||
| Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein) | |||
| Putative ribosome-binding factor A, mitochondrial | Mitochondrion | ||
| F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit) | Cytoplasm | ||
| Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance regulatory protein ICln) (I(Cln)) (Chloride ion current inducer protein) (ClCI) (Reticulocyte pICln) | Cytoplasm, cytosol | ||
| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57) (BAF57) | Nucleus | ||
| Kinesin-like protein KIF1C | autosomal recessive cerebellar ataxia spastic ataxia | Cytoplasm, cytoskeleton | |
| Influenza virus NS1A-binding protein (NS1-BP) (NS1-binding protein) (Aryl hydrocarbon receptor-associated protein 3) (Kelch-like protein 39) | Cytoplasm | ||
| H/ACA ribonucleoprotein complex non-core subunit NAF1 (hNAF1) | |||
| Uncharacterized protein MISP3 (MISP family member 3) | |||
| Syntaxin-6 | Golgi apparatus membrane | ||
| Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101) | Cytoplasm | ||
| Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A) | Mitochondrion outer membrane | ||
| Telomerase reverse transcriptase (EC 2.7.7.49) (HEST2) (Telomerase catalytic subunit) (Telomerase-associated protein 2) (TP2) | Nucleus, nucleolus | ||
| Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Renal carcinoma antigen NY-REN-42) | Cytoplasm | ||
| Sulfite oxidase, mitochondrial (EC 1.8.3.1) | Mitochondrion intermembrane space. | ||
| Unconventional myosin-Ie (Myosin-Ic) (Unconventional myosin 1E) | multiple sclerosis | Cytoplasm | |
| Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) | Cytoplasm | ||
| T-cell surface glycoprotein CD4 (T-cell surface antigen T4/Leu-3) (CD antigen CD4) | Cell membrane | ||
| Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2) | Secreted. | ||
| Catalase (EC 1.11.1.6) | Peroxisome. | ||
| Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase (EC 4.2.1.17) (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)] | Peroxisome. | ||
| Protein SET (HLA-DR-associated protein II) (Inhibitor of granzyme A-activated DNase) (IGAAD) (PHAPII) (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I) | |||
| Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1) | Cytoplasm | ||
| Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l) | Nucleus | ||
| Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 2) (Neural enolase) (Neuron-specific enolase) (NSE) | Cytoplasm | ||
| Small ubiquitin-related modifier 4 (SUMO-4) (Small ubiquitin-like protein 4) | |||
| B-cell receptor-associated protein 31 (BCR-associated protein 31) (Bap31) (6C6-AG tumor-associated antigen) (Protein CDM) (p28) | Endoplasmic reticulum membrane | ||
| Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12) (Deubiquitinating enzyme 20) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (VHL-interacting deubiquitinating enzyme 2) (hVDU2) | Cytoplasm, perinuclear region | ||
| Syntaxin-2 (Epimorphin) | Membrane | ||
| Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH) | Nucleus | ||
| Fanconi anemia group A protein (Protein FACA) | |||
| Deleted in autism protein 1 (Golgi Protein of 49 kDa) (GoPro49) (Hypoxia and AKT-induced stem cell factor) (HASF) | autism spectrum disorder | Cytoplasmic vesicle, COPI-coated vesicle | |
| Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35) | Parkinson disease | Cytoplasm | |
| F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2) | Cytoplasm | ||
| ER membrane protein complex subunit 1 | multiple system atrophy | Membrane | |
| TOMM20-like protein 1 | Mitochondrion outer membrane | ||
| Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) (Muscle form hexokinase) | Mitochondrion outer membrane | ||
| Histone H2AX (H2a/x) (Histone H2A.X) | Nucleus | ||
| TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1) | Nucleus | ||
| Matrilin-2 | Secreted. | ||
| CDC42 small effector protein 1 (CDC42-binding protein SCIP1) (Small effector of CDC42 protein 1) | |||
| Ras-related protein Rab-34 (Ras-related protein Rab-39) (Ras-related protein Rah) | Cytoplasm | ||
| RING finger protein 10 | Cytoplasm | ||
| E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1) | autosomal dominant cerebellar ataxia autosomal recessive cerebellar ataxia | Cytoplasm | |
| Protein phosphatase 1A (EC 3.1.3.16) (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (Protein phosphatase IA) | Nucleus | ||
| ATP-dependent RNA helicase DHX30 (EC 3.6.4.13) (DEAH box protein 30) | Cytoplasm | ||
| T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed] | Cytoplasm | ||
| Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1) | Cytoplasm | ||
| COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1) | Cytoplasm, cytosol | ||
| Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) | Cytoplasm | ||
| Probable ergosterol biosynthetic protein 28 | Endoplasmic reticulum membrane | ||
| Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2) | |||
| Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha) | Nucleus | ||
| ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein) (NAD(P)HX dehydratase) | Mitochondrion | ||
| Thyroid hormone receptor alpha (Nuclear receptor subfamily 1 group A member 1) (V-erbA-related protein 7) (EAR-7) (c-erbA-1) (c-erbA-alpha) | Nucleus. | ||
| Histone deacetylase 2 (HD2) (EC 3.5.1.98) | Nucleus | ||
| Uncharacterized protein RAB5IF (Rab5-interacting protein) (RIP5) | |||
| Forkhead box protein J2 (Fork head homologous X) | Nucleus. | ||
| CST complex subunit STN1 (Oligonucleotide/oligosaccharide-binding fold-containing protein 1) (Suppressor of cdc thirteen homolog) | Nucleus | ||
| Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181) | Nucleus | ||
| Transforming acidic coiled-coil-containing protein 3 (ERIC-1) | Cytoplasm | ||
| Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) | Nucleus | ||
| Glycerate kinase (EC 2.7.1.31) (HBeAg-binding protein 4) | Isoform 1: Cytoplasm | ||
| Melanoma-associated antigen 10 (Cancer/testis antigen 1.10) (CT1.10) (MAGE-10 antigen) | Nucleus | ||
| 28S ribosomal protein S24, mitochondrial (MRP-S24) (S24mt) (Mitochondrial small ribosomal subunit protein uS3m) (bMRP-47) (bMRP47) | Mitochondrion | ||
| Retinoblastoma-associated protein (p105-Rb) (pRb) (Rb) (pp110) | Nucleus | ||
| Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6) | Parkinson disease | ||
| CREB-binding protein (EC 2.3.1.48) | |||
| WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1) | Cytoplasm | ||
| Cytoplasmic dynein 2 light intermediate chain 1 (Dynein 2 light intermediate chain) | Cytoplasm | ||
| Forkhead box protein P1 (Mac-1-regulated forkhead) (MFH) | autism spectrum disorder | Nucleus | |
| Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit) | |||
| ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5) | Isoform Beta: Nucleus, nucleoplasm | ||
| Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin-specific peptidase 50) | |||
| Forkhead box protein O1 (Forkhead box protein O1A) (Forkhead in rhabdomyosarcoma) | Cytoplasm | ||
| Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2) | Mitochondrion | ||
| Forkhead box protein K2 (Cellular transcription factor ILF-1) (FOXK1) (Interleukin enhancer-binding factor 1) | Nucleus | ||
| Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor) | Cell membrane | ||
| Probable tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase) (hOSGEP) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP) (tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP) | Cytoplasm | ||
| DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1) | |||
| TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa) | |||
| Zinc transporter ZIP4 (Solute carrier family 39 member 4) (Zrt- and Irt-like protein 4) (ZIP-4) | Cell membrane | ||
| Forkhead box protein N1 (Winged-helix transcription factor nude) | Nucleus. | ||
| Nuclear factor of activated T-cells, cytoplasmic 1 (NF-ATc1) (NFATc1) (NFAT transcription complex cytosolic component) (NF-ATc) (NFATc) | Cytoplasm | ||
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (EC 5.2.1.8) (Parvulin-14) (Par14) (hPar14) (Parvulin-17) (Par17) (hPar17) (Peptidyl-prolyl cis-trans isomerase Pin4) (PPIase Pin4) (Peptidyl-prolyl cis/trans isomerase EPVH) (hEPVH) (Rotamase Pin4) | |||
| Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) | Cell junction, desmosome | ||
| Putative ubiquitin-conjugating enzyme E2 D2-like protein (Ubiquitin carrier protein D2-like) (Ubiquitin-conjugating enzyme E2D N-terminal-like) (Ubiquitin-protein ligase D2-like) | |||
| Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued) | progressive muscular atrophy lateral sclerosis spinal muscular atrophy ... amyotrophic lateral sclerosis multiple system atrophy | Cytoplasm | |
| Phosphoglucomutase-1 (PGM 1) (EC 5.4.2.2) (Glucose phosphomutase 1) | Isoform 1: Cytoplasm. | ||
| Nebulin | Cytoplasm, myofibril, sarcomere | ||
| Spectrin beta chain, erythrocytic (Beta-I spectrin) | Cytoplasm, cytoskeleton | ||
| SNARE-associated protein Snapin (Biogenesis of lysosome-related organelles complex 1 subunit 7) (BLOC-1 subunit 7) (Synaptosomal-associated protein 25-binding protein) (SNAP-associated protein) | Membrane | ||
| Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain) | Cytoplasm | ||
| IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5) (p53 and DNA damage-regulated IQ motif protein) (PIQ) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (p58) | Cytoplasm | ||
| Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) | |||
| Intracellular hyaluronan-binding protein 4 (IHABP-4) (IHABP4) (Hyaluronan-binding protein 4) (Ki-1/57 intracellular antigen) | Nucleus | ||
| Annexin A11 (56 kDa autoantigen) (Annexin XI) (Annexin-11) (Calcyclin-associated annexin 50) (CAP-50) | lateral sclerosis amyotrophic lateral sclerosis | Cytoplasm | |
| WD repeat-containing protein 19 (Intraflagellar transport 144 homolog) | Cell projection, cilium | ||
| N-acetyltransferase 9 (EC 2.3.1.-) (Embryo brain-specific protein) | |||
| Snurportin-1 (RNA U transporter 1) | Nucleus | ||
| Hexokinase-1 (EC 2.7.1.1) (Brain form hexokinase) (Hexokinase type I) (HK I) | |||
| POC1 centriolar protein homolog A (Pix2) (Proteome of centriole protein 1A) (WD repeat-containing protein 51A) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2) | Nucleus | ||
| Ubiquitin-conjugating enzyme E2 C (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme C) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme C) (UbcH10) (Ubiquitin carrier protein C) (Ubiquitin-protein ligase C) | |||
| Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1) | Nucleus | ||
| Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A) (Autophagy-related ubiquitin-like modifier LC3 A) (MAP1 light chain 3-like protein 1) (MAP1A/MAP1B light chain 3 A) (MAP1A/MAP1B LC3 A) (Microtubule-associated protein 1 light chain 3 alpha) | Cytoplasm, cytoskeleton | ||
| Calcium-binding protein 39 (MO25alpha) (Protein Mo25) | Cytoplasm | ||
| Telomeric repeat-binding factor 1 (NIMA-interacting protein 2) (TTAGGG repeat-binding factor 1) (Telomeric protein Pin2/TRF1) | |||
| Emopamil-binding protein-like (Emopamil-binding-related protein) | Endoplasmic reticulum membrane | ||
| Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) | Cell membrane | ||
| Alpha-endosulfine (ARPP-19e) | Cytoplasm | ||
| mRNA-decapping enzyme 1A (EC 3.-.-.-) (Smad4-interacting transcriptional co-activator) (Transcription factor SMIF) | Cytoplasm, P-body | ||
| Microtubule-associated protein 4 (MAP-4) | Cytoplasm, cytoskeleton. | ||
| mRNA decay activator protein ZFP36 (G0/G1 switch regulatory protein 24) (Growth factor-inducible nuclear protein NUP475) (Tristetraprolin) (Zinc finger protein 36) (Zfp-36) | Nucleus | ||
| Tubulin alpha-4A chain (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain) | lateral sclerosis amyotrophic lateral sclerosis | Cytoplasm, cytoskeleton. | |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 1.6.99.3) (EC 7.1.1.2) (Complex I-20kD) (CI-20kD) (NADH-ubiquinone oxidoreductase 20 kDa subunit) (PSST subunit) | Parkinson disease | Mitochondrion | |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (Complex I-39kD) (CI-39kD) (NADH-ubiquinone oxidoreductase 39 kDa subunit) | Parkinson disease | Mitochondrion matrix | |
| 39S ribosomal protein L12, mitochondrial (L12mt) (MRP-L12) (5c5-2) (Mitochondrial large ribosomal subunit protein bL12m) | Mitochondrion | ||
| DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D) (RNA polymerase I 16 kDa subunit) (RPA16) (RPC16) (hRPA19) | Nucleus | ||
| Cytochrome c oxidase subunit 6C (Cytochrome c oxidase polypeptide VIc) | Mitochondrion inner membrane. | ||
| Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va) | Mitochondrion inner membrane. | ||
| Endothelin receptor type B (ET-B) (ET-BR) (Endothelin receptor non-selective type) | Cell membrane | ||
| Cytochrome c oxidase subunit 6B1 (Cytochrome c oxidase subunit VIb isoform 1) (COX VIb-1) | Mitochondrion intermembrane space | ||
| Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 1.10.2.2) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Rieske protein UQCRFS1) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 9 (Su9) (Subunit 9) (8 kDa subunit 9) (Complex III subunit IX) (Cytochrome b-c1 complex subunit 11) (Ubiquinol-cytochrome c reductase 8 kDa protein)] | Mitochondrion inner membrane | ||
| Zinc finger protein 414 | Nucleus | ||
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (Complex I-13kD-A) (CI-13kD-A) (NADH-ubiquinone oxidoreductase 13 kDa-A subunit) | Parkinson disease | Mitochondrion inner membrane | |
| Tetratricopeptide repeat protein 4 (TPR repeat protein 4) | |||
| Cysteine and histidine-rich domain-containing protein 1 (CHORD domain-containing protein 1) (CHORD-containing protein 1) (CHP-1) (Protein morgana) | |||
| Cytochrome c oxidase subunit 7A2, mitochondrial (Cytochrome c oxidase subunit VIIa-liver/heart) (Cytochrome c oxidase subunit VIIa-L) (Cytochrome c oxidase subunit VIIaL) | Mitochondrion inner membrane. | ||
| X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)) | Nucleus | ||
| Myosin-6 (Myosin heavy chain 6) (Myosin heavy chain, cardiac muscle alpha isoform) (MyHC-alpha) | |||
| Vacuolar protein sorting-associated protein 26A (Vesicle protein sorting 26A) (hVPS26) | Cytoplasm | ||
| Protein mab-21-like 2 | Nucleus | ||
| Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain) | Nucleus | ||
| NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC 1.6.99.3) (EC 7.1.1.2) (Complex I-51kD) (CI-51kD) (NADH dehydrogenase flavoprotein 1) (NADH-ubiquinone oxidoreductase 51 kDa subunit) | Parkinson disease | Mitochondrion inner membrane | |
| Homer protein homolog 1 (Homer-1) | Cytoplasm | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (CI-B14) (LYR motif-containing protein 6) (NADH-ubiquinone oxidoreductase B14 subunit) | Mitochondrion inner membrane | ||
| NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 1.6.99.3) (EC 7.1.1.2) (Complex I-75kD) (CI-75kD) | Parkinson disease | Mitochondrion inner membrane. | |
| NADH dehydrogenase [ubiquinone] 1 subunit C2 (Complex I-B14.5b) (CI-B14.5b) (Human lung cancer oncogene 1 protein) (HLC-1) (NADH-ubiquinone oxidoreductase subunit B14.5b) | Mitochondrion inner membrane | ||
| Mitochondrial intermembrane space import and assembly protein 40 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4) | Mitochondrion intermembrane space | ||
| Complement component 1 Q subcomponent-binding protein, mitochondrial (ASF/SF2-associated protein p32) (Glycoprotein gC1qBP) (C1qBP) (Hyaluronan-binding protein 1) (Mitochondrial matrix protein p32) (gC1q-R protein) (p33) (SF2AP32) | Mitochondrion matrix | ||
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (Complex I-18 kDa) (CI-18 kDa) (Complex I-AQDQ) (CI-AQDQ) (NADH-ubiquinone oxidoreductase 18 kDa subunit) | Parkinson disease | Mitochondrion inner membrane | |
| Cytochrome c oxidase subunit 6A1, mitochondrial (Cytochrome c oxidase polypeptide VIa-liver) (Cytochrome c oxidase subunit VIA-liver) (COX VIa-L) | Mitochondrion inner membrane. | ||
| Peroxisome biogenesis factor 10 (Peroxin-10) (Peroxisomal biogenesis factor 10) (Peroxisome assembly protein 10) (RING finger protein 69) | Peroxisome membrane | ||
| Cytochrome c oxidase subunit 2 (Cytochrome c oxidase polypeptide II) | Mitochondrion inner membrane | ||
| Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33) | Endoplasmic reticulum membrane | ||
| Zinc finger protein 503 | Nucleus | ||
| Granulins (Proepithelin) (PEPI) [Cleaved into: Acrogranin (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Progranulin); Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] | Secreted. | ||
| DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19) | Nucleus | ||
| Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 (EC 2.4.1.141) (EC 3.4.19.12) (Asparagine-linked glycosylation 13 homolog) (Glycosyltransferase 28 domain-containing protein 1) (UDP-N-acetylglucosamine transferase subunit ALG13 homolog) | Isoform 2: Endoplasmic reticulum | ||
| Complex I assembly factor TIMMDC1, mitochondrial (Protein M5-14) (Translocase of inner mitochondrial membrane domain-containing protein 1) (TIMM domain containing-protein 1) | Mitochondrion membrane | ||
| Cytochrome b-c1 complex subunit 7 (Complex III subunit 7) (Complex III subunit VII) (QP-C) (Ubiquinol-cytochrome c reductase complex 14 kDa protein) | Mitochondrion inner membrane. | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Complex I-42kD) (CI-42kD) (NADH-ubiquinone oxidoreductase 42 kDa subunit) | Parkinson disease | Mitochondrion matrix | |
| Synaptosomal-associated protein 29 (SNAP-29) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29) | Cytoplasm | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (Complex I-B14.5a) (CI-B14.5a) (NADH-ubiquinone oxidoreductase subunit B14.5a) | Mitochondrion inner membrane | ||
| B-cell lymphoma/leukemia 11B (BCL-11B) (B-cell CLL/lymphoma 11B) (COUP-TF-interacting protein 2) (Radiation-induced tumor suppressor gene 1 protein) (hRit1) | lateral sclerosis multiple sclerosis | Nucleus | |
| Transmembrane protein 132A (HSPA5-binding protein 1) | Golgi apparatus membrane | ||
| Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1) | Cell membrane | ||
| Zinc finger protein 524 | Nucleus | ||
| Delta-type opioid receptor (D-OR-1) (DOR-1) | Cell membrane | ||
| Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP) | Cell membrane | ||
| Zinc finger and BTB domain-containing protein 22 (Protein BING1) (Zinc finger and BTB domain-containing protein 22A) (Zinc finger protein 297) | Nucleus | ||
| Occludin | Cell membrane | ||
| Caveolin-1 | Golgi apparatus membrane | ||
| Nucleolar complex protein 4 homolog (NOC4 protein homolog) (NOC4-like protein) (Nucleolar complex-associated protein 4-like protein) | Nucleus membrane | ||
| Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain-interacting protein) (SSX2-interacting protein) | Cell junction, adherens junction | ||
| C2 calcium-dependent domain-containing protein 6 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein) | lateral sclerosis | ||
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (Complex I-ESSS) (CI-ESSS) (NADH-ubiquinone oxidoreductase ESSS subunit) (Neuronal protein 17.3) (Np17.3) (p17.3) | Parkinson disease | Mitochondrion inner membrane | |
| Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor alpha-induced protein 4) (TNF alpha-induced protein 4) [Cleaved into: Ephrin-A1, secreted form] | Cell membrane | ||
| Homeobox protein MOX-1 (Mesenchyme homeobox 1) | Nucleus | ||
| Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1) | Nucleus | ||
| Serum albumin | Secreted. | ||
| Deoxyribonuclease-2-beta (EC 3.1.22.1) (DNase II-like acid DNase) (DNase2-like acid DNase) (Deoxyribonuclease II beta) (DNase II beta) (Endonuclease DLAD) | Lysosome | ||
| N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Polypeptide GalNAc transferase 7) (GalNAc-T7) (pp-GaNTase 7) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) | Golgi apparatus membrane | ||
| Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (Protein 59) (Protein DMR-N9) | Perikaryon | ||
| Ras-related protein Rab-10 | Cytoplasmic vesicle membrane | ||
| CUGBP Elav-like family member 1 (CELF-1) (50 kDa nuclear polyadenylated RNA-binding protein) (Bruno-like protein 2) (CUG triplet repeat RNA-binding protein 1) (CUG-BP1) (CUG-BP- and ETR-3-like factor 1) (Deadenylation factor CUG-BP) (Embryo deadenylation element-binding protein homolog) (EDEN-BP homolog) (RNA-binding protein BRUNOL-2) | Nucleus | ||
| 40S ribosomal protein S27 (Metallopan-stimulin 1) (MPS-1) (Small ribosomal subunit protein eS27) | |||
| E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX) | Cytoplasm | ||
| Protein unc-93 homolog B1 (Unc-93B1) (hUNC93B1) | Endoplasmic reticulum membrane | ||
| Transcription factor IIIA (TFIIIA) | Nucleus. | ||
| Rap1 GTPase-GDP dissociation stimulator 1 (Exchange factor smgGDS) (SMG GDS protein) (SMG P21 stimulatory GDP/GTP exchange protein) | |||
| Protein unc-13 homolog B (Munc13-2) (munc13) | Cytoplasm | ||
| Ras-related protein Rab-32 | Mitochondrion | ||
| Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (GluA1) | Cell membrane | ||
| C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (FB22) (Fusin) (HM89) (LCR1) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (Lipopolysaccharide-associated protein 3) (LAP-3) (LPS-associated protein 3) (NPYRL) (Stromal cell-derived factor 1 receptor) (SDF-1 receptor) (CD antigen CD184) | Cell membrane | ||
| Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Protein-tyrosine phosphatase SHP-1) (SH-PTP1) | |||
| Sialomucin core protein 24 (MUC-24) (Endolyn) (Multi-glycosylated core protein 24) (MGC-24) (MGC-24v) (CD antigen CD164) | Lysosome membrane | ||
| Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35) | Nucleus | ||
| Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) | Cytoplasm | ||
| IQ domain-containing protein F1 | Cytoplasmic vesicle, secretory vesicle, acrosome | ||
| Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3) | Cytoplasm | ||
| Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK) | Cell junction, focal adhesion | ||
| Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b) | Cell membrane | ||
| Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3) | Cytoplasm | ||
| Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit) | |||
| Myb-related protein B (B-Myb) (Myb-like protein 2) | Nucleus. | ||
| Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2) | Endomembrane system | ||
| Cation-transporting ATPase 13A2 (EC 3.6.3.-) | Parkinson disease | Membrane | |
| Microtubule-associated protein RP/EB family member 3 (EB1 protein family member 3) (EBF3) (End-binding protein 3) (EB3) (RP3) | Cytoplasm, cytoskeleton | ||
| HLA class I histocompatibility antigen, B-7 alpha chain (MHC class I antigen B*7) | Membrane | ||
| Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK) | Endomembrane system | ||
| HLA class II histocompatibility antigen gamma chain (HLA-DR antigens-associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD antigen CD74) | Cell membrane | ||
| Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3) | Nucleus | ||
| Guanine nucleotide-binding protein subunit alpha-13 (G alpha-13) (G-protein subunit alpha-13) | Cell membrane | ||
| Palmitoyl-protein thioesterase 1 (PPT-1) (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1) | Lysosome | ||
| Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) | Cytoplasm, cytoskeleton | ||
| Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase) | Cytoplasm, cytosol | ||
| Cytochrome c | |||
| Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5) | Cytoplasm | ||
| Cytochrome P450 2E1 (EC 1.14.13.-) (4-nitrophenol 2-hydroxylase) (EC 1.14.13.n7) (CYPIIE1) (Cytochrome P450-J) | Endoplasmic reticulum membrane | ||
| (E3-independent) E2 ubiquitin-conjugating enzyme (EC 2.3.2.24) (E2/E3 hybrid ubiquitin-protein ligase UBE2O) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O) | Cytoplasm | ||
| P2X purinoceptor 4 (P2X4) (ATP receptor) (Purinergic receptor) | Membrane | ||
| Galectin-9C (Gal-9C) (Galectin-9-like protein B) | |||
| Cyclic AMP-responsive element-binding protein 3 (CREB-3) (cAMP-responsive element-binding protein 3) (Leucine zipper protein) (Luman) (Transcription factor LZIP-alpha) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3 (N-terminal Luman) (Transcriptionally active form)] | Isoform 1: Endoplasmic reticulum membrane | ||
| Protein C-ets-1 (p54) | Cytoplasm | ||
| L-lactate dehydrogenase A-like 6B (EC 1.1.1.27) | |||
| Cyclic AMP-responsive element-binding protein 3-like protein 1 (cAMP-responsive element-binding protein 3-like protein 1) (Old astrocyte specifically-induced substance) (OASIS) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 1] | Endoplasmic reticulum membrane | ||
| Transcription initiation factor IIA subunit 1 (General transcription factor IIA subunit 1) (TFIIAL) (Transcription initiation factor TFIIA 42 kDa subunit) (TFIIA-42) [Cleaved into: Transcription initiation factor IIA alpha chain (TFIIA p35 subunit); Transcription initiation factor IIA beta chain (TFIIA p19 subunit)] | Nucleus. | ||
| Calcyclin-binding protein (CacyBP) (hCacyBP) (S100A6-binding protein) (Siah-interacting protein) | Nucleus | ||
| Inositol 1,4,5-trisphosphate receptor-interacting protein (Protein DANGER) | Cell membrane | ||
| RNA polymerase II-associated protein 3 | |||
| Probable dimethyladenosine transferase (EC 2.1.1.183) (DIM1 dimethyladenosine transferase 1 homolog) (DIM1 dimethyladenosine transferase 1-like) (Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase) (Probable 18S rRNA dimethylase) (Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase) | Nucleus, nucleoplasm | ||
| Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) | Cytoplasm, cytoskeleton, spindle | ||
| Metaxin-1 (Mitochondrial outer membrane import complex protein 1) | Membrane | ||
| General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (Basic transcription factor 2 80 kDa subunit) (BTF2 p80) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (TFIIH basal transcription factor complex 80 kDa subunit) (TFIIH 80 kDa subunit) (TFIIH p80) (Xeroderma pigmentosum group D-complementing protein) | Nucleus | ||
| RNA cytidine acetyltransferase (EC 2.3.1.-) (18S rRNA cytosine acetyltransferase) (N-acetyltransferase 10) | Nucleus, nucleolus | ||
| Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase) | Cytoplasm | ||
| Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340) | |||
| WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein) | |||
| Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2) (Kelch-like protein 19) | |||
| Unconventional prefoldin RPB5 interactor 1 (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein) | Nucleus | ||
| Unconventional myosin-IXb (Unconventional myosin-9b) | Cytoplasm, cell cortex | ||
| Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.4.19.12) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) | |||
| Nephrocystin-4 (Nephroretinin) | Cytoplasm, cytoskeleton, cilium basal body | ||
| Protein 4.1 (P4.1) (4.1R) (Band 4.1) (EPB4.1) | Cytoplasm, cytoskeleton | ||
| Pantothenate kinase 2, mitochondrial (hPanK2) (EC 2.7.1.33) (Pantothenic acid kinase 2) | pantothenate kinase-associated neurodegeneration | Isoform 1: Mitochondrion. | |
| OTU domain-containing protein 5 (EC 3.4.19.12) (Deubiquitinating enzyme A) (DUBA) | |||
| Guanine nucleotide-binding protein subunit alpha-15 (G alpha-15) (G-protein subunit alpha-15) (Epididymis tissue protein Li 17E) (Guanine nucleotide-binding protein subunit alpha-16) (G alpha-16) (G-protein subunit alpha-16) | |||
| E3 ubiquitin-protein ligase SIAH1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH1) (Seven in absentia homolog 1) (Siah-1) (Siah-1a) | Parkinson disease | ||
| Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT) | autosomal recessive cerebellar ataxia | Endoplasmic reticulum | |
| Cystatin-S (Cystatin-4) (Cystatin-SA-III) (Salivary acidic protein 1) | Secreted | ||
| Follistatin (FS) (Activin-binding protein) | Secreted. | ||
| Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) | Membrane | ||
| Archaemetzincin-2 (EC 3.4.-.-) (Archeobacterial metalloproteinase-like protein 2) | |||
| Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK) | Mitochondrion. | ||
| Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) | |||
| POTE ankyrin domain family member I | |||
| F-box-like/WD repeat-containing protein TBL1X (SMAP55) (Transducin beta-like protein 1X) (Transducin-beta-like protein 1, X-linked) | Nucleus | ||
| Nephrocystin-1 (Juvenile nephronophthisis 1 protein) | autosomal recessive cerebellar ataxia primary cerebellar degeneration | Cell junction, adherens junction | |
| Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.4.19.12) (Deubiquitinating enzyme 49) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) | Nucleus | ||
| Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (51 kDa FK506-binding protein) (FKBP51) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed] | Cytoplasm, cytosol | ||
| Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) (Proto-oncogene c-Mos) | |||
| Protein BEX3 (Brain-expressed X-linked protein 3) (Nerve growth factor receptor-associated protein 1) (Ovarian granulosa cell 13.0 kDa protein HGR74) (p75NTR-associated cell death executor) | |||
| Centrosomal protein of 104 kDa (Cep104) | autosomal recessive cerebellar ataxia | Cell projection, cilium | |
| Ras-related C3 botulinum toxin substrate 3 (p21-Rac3) | |||
| Transcription factor E3 (Class E basic helix-loop-helix protein 33) (bHLHe33) | Nucleus. | ||
| E3 ubiquitin-protein ligase SIAH2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH2) (Seven in absentia homolog 2) (Siah-2) (hSiah2) | Cytoplasm | ||
| Eukaryotic translation initiation factor 6 (eIF-6) (B(2)GCN homolog) (B4 integrin interactor) (CAB) (p27(BBP)) | |||
| CCR4-NOT transcription complex subunit 8 (EC 3.1.13.4) (CAF1-like protein) (CALIFp) (CAF2) (CCR4-associated factor 8) (Caf1b) | Cytoplasm | ||
| Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 | Cell membrane | ||
| Proto-oncogene c-Fos (Cellular oncogene fos) (G0/G1 switch regulatory protein 7) | |||
| Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (G gamma-I) | Cell membrane | ||
| F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6) | |||
| Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | Cell membrane | ||
| 5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb) | |||
| Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13) | Cytoplasm | ||
| Nucleoside diphosphate kinase B (NDK B) (NDP kinase B) (EC 2.7.4.6) (C-myc purine-binding transcription factor PUF) (Histidine protein kinase NDKB) (EC 2.7.13.3) (nm23-H2) | Cytoplasm | ||
| CASP8 and FADD-like apoptosis regulator (Caspase homolog) (CASH) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (Cellular FLICE-like inhibitory protein) (c-FLIP) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Inhibitor of FLICE) (I-FLICE) (MACH-related inducer of toxicity) (MRIT) (Usurpin) [Cleaved into: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12] | lateral sclerosis | ||
| Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12) | Cell membrane | ||
| Neuroendocrine secretory protein 55 (NESP55) [Cleaved into: LHAL tetrapeptide; GPIPIRRH peptide] | Cytoplasmic vesicle, secretory vesicle | ||
| Kelch-like protein 38 | |||
| Homeobox protein Meis2 (Meis1-related protein 1) | Nucleus | ||
| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 (60 kDa BRG-1/Brm-associated factor subunit B) (BRG1-associated factor 60B) (BAF60B) | Nucleus | ||
| E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1) | |||
| S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (p19A) (Organ of Corti protein 2) (OCP-2) (Organ of Corti protein II) (OCP-II) (RNA polymerase II elongation factor-like protein) (SIII) (Transcription elongation factor B polypeptide 1-like) (p19skp1) | |||
| Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas) | Cell membrane | ||
| BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2) | |||
| Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin) | Cytoplasm | ||
| Ubl carboxyl-terminal hydrolase 18 (EC 3.4.19.-) (43 kDa ISG15-specific protease) (hUBP43) (ISG15-specific-processing protease) (Ubl thioesterase 18) | Isoform 1: Cytoplasm | ||
| Heat shock protein beta-8 (HspB8) (Alpha-crystallin C chain) (E2-induced gene 1 protein) (Protein kinase H11) (Small stress protein-like protein HSP22) | Cytoplasm | ||
| SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18) | |||
| Prenylated Rab acceptor protein 1 (PRA1 family protein 1) | Cell membrane | ||
| Acyl-CoA dehydrogenase family member 11 (ACAD-11) (EC 1.3.99.-) | Peroxisome | ||
| Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase) | Mitochondrion | ||
| Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3) | |||
| Proteasome subunit alpha type-1 (EC 3.4.25.1) (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain) | Cytoplasm | ||
| Peptidyl-tRNA hydrolase ICT1, mitochondrial (EC 3.1.1.29) (39S ribosomal protein L58, mitochondrial) (MRP-L58) (Digestion substraction 1) (DS-1) (Immature colon carcinoma transcript 1 protein) (Mitochondrial large ribosomal subunit protein mL62) | Mitochondrion | ||
| Membrane magnesium transporter 1 (ER membrane protein complex subunit 5) (Transmembrane protein 32) | Endoplasmic reticulum membrane | ||
| Upstream stimulatory factor 1 (Class B basic helix-loop-helix protein 11) (bHLHb11) (Major late transcription factor 1) | Nucleus. | ||
| Cytochrome c oxidase subunit 5B, mitochondrial (Cytochrome c oxidase polypeptide Vb) | Mitochondrion inner membrane. | ||
| Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1) | Cytoplasm, cytoskeleton | ||
| ATP-dependent zinc metalloprotease YME1L1 (EC 3.4.24.-) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin-associated metalloprotease) (PAMP) (YME1-like protein 1) | Mitochondrion inner membrane | ||
| Dynactin subunit 5 (Dynactin subunit p25) | Cytoplasm, cytoskeleton | ||
| ADP/ATP translocase 2 (ADP,ATP carrier protein 2) (ADP,ATP carrier protein, fibroblast isoform) (Adenine nucleotide translocator 2) (ANT 2) (Solute carrier family 25 member 5) [Cleaved into: ADP/ATP translocase 2, N-terminally processed] | Mitochondrion inner membrane | ||
| Cytochrome c oxidase subunit NDUFA4 (Complex I-MLRQ) (CI-MLRQ) (NADH-ubiquinone oxidoreductase MLRQ subunit) | Mitochondrion inner membrane | ||
| Protein bicaudal D homolog 2 (Bic-D 2) | spinal muscular atrophy | Golgi apparatus | |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (Complex I-15 kDa) (CI-15 kDa) (NADH-ubiquinone oxidoreductase 15 kDa subunit) | Mitochondrion inner membrane | ||
| Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) | Cytoplasm, cytoskeleton, cilium axoneme | ||
| Normal mucosa of esophagus-specific gene 1 protein (Protein FOAP-11) | Nucleus | ||
| Melanoma-associated antigen 11 (Cancer/testis antigen 1.11) (CT1.11) (MAGE-11 antigen) | Nucleus | ||
| Apolipoprotein E (Apo-E) | Alzheimer disease | Secreted | |
| Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) | Cell membrane | ||
| Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (CIG49) (ISG-60) (Interferon-induced 60 kDa protein) (IFI-60K) (Interferon-induced protein with tetratricopeptide repeats 4) (IFIT-4) (Retinoic acid-induced gene G protein) (P60) (RIG-G) | Cytoplasm | ||
| Protein lin-52 homolog | |||
| Ret finger protein-like 2 (RING finger protein 79) | |||
| DnaJ homolog subfamily B member 1 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40) (Human DnaJ protein 1) (hDj-1) | Cytoplasm | ||
| Bleomycin hydrolase (BH) (BLM hydrolase) (BMH) (EC 3.4.22.40) | Cytoplasm. | ||
| Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1) | Golgi apparatus, cis-Golgi network | ||
| Desmoglein-3 (130 kDa pemphigus vulgaris antigen) (PVA) (Cadherin family member 6) | Cell membrane | ||
| Zinc finger and BTB domain-containing protein 25 (Zinc finger protein 46) (Zinc finger protein KUP) | Nucleus. | ||
| Putative uncharacterized protein C17orf82 | |||
| DCC-interacting protein 13-beta (Dip13-beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2) | Early endosome membrane | ||
| Protein arginine N-methyltransferase 6 (EC 2.1.1.319) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6) (Histone-arginine N-methyltransferase PRMT6) | Nucleus | ||
| Lysine-specific histone demethylase 1A (EC 1.-.-.-) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) | Nucleus | ||
| WD repeat-containing protein 48 (USP1-associated factor 1) (WD repeat endosomal protein) (p80) | Nucleus | ||
| Pre-mRNA 3'-end-processing factor FIP1 (hFip1) (FIP1-like 1 protein) (Factor interacting with PAP) (Rearranged in hypereosinophilia) | Nucleus. | ||
| Golgi reassembly-stacking protein 2 (GRS2) (Golgi phosphoprotein 6) (GOLPH6) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59) | Golgi apparatus membrane | ||
| Maspardin (Acid cluster protein 33) (Spastic paraplegia 21 autosomal recessive Mast syndrome protein) (Spastic paraplegia 21 protein) | Cytoplasm, cytosol | ||
| Apoptosis regulator BAX (Bcl-2-like protein 4) (Bcl2-L-4) | Isoform Alpha: Mitochondrion outer membrane | ||
| Ras association domain-containing protein 3 | Cytoplasm | ||
| Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X) | Isoform Bcl-X(L): Mitochondrion inner membrane | ||
| Zinc finger CCCH domain-containing protein 4 | |||
| Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit) | |||
| Calsenilin (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3) | Cytoplasm | ||
| Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2) | autism spectrum disorder | Cell membrane | |
| Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57) | |||
| Transmembrane 4 L6 family member 18 | Membrane | ||
| C-terminal-binding protein 2 (CtBP2) | Nucleus | ||
| Pterin-4-alpha-carbinolamine dehydratase 2 (PHS 2) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase 2) (DcoH-like protein DCoHm) (Dimerization cofactor of hepatocyte nuclear factor 1 from muscle) (HNF-1-alpha dimerization cofactor) | |||
| RISC-loading complex subunit TARBP2 (TAR RNA-binding protein 2) (Trans-activation-responsive RNA-binding protein) | Cytoplasm | ||
| RWD domain-containing protein 2A | |||
| Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA) | Mitochondrion outer membrane | ||
| cAMP-responsive element modulator (Inducible cAMP early repressor) (ICER) | Nucleus. | ||
| C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) | Cytoplasm | ||
| A-kinase anchor protein 5 (AKAP-5) (A-kinase anchor protein 79 kDa) (AKAP 79) (H21) (cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein) | Membrane | ||
| Battenin (Batten disease protein) (Protein CLN3) | Lysosome membrane | ||
| Cyclic AMP-responsive element-binding protein 1 (CREB-1) (cAMP-responsive element-binding protein 1) | Nucleus | ||
| Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calmodulin-dependent calcineurin A subunit alpha isoform) | Cytoplasm | ||
| Presenilin-2 (PS-2) (EC 3.4.23.-) (AD3LP) (AD5) (E5-1) (STM-2) [Cleaved into: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit] | Alzheimer disease | Endoplasmic reticulum membrane | |
| Mothers against decapentaplegic homolog 9 (MAD homolog 9) (Mothers against DPP homolog 9) (Madh6) (SMAD family member 9) (SMAD 9) (Smad9) | Cytoplasm | ||
| GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53) | Cytoplasm | ||
| Glypican-1 [Cleaved into: Secreted glypican-1] | Pick disease Alzheimer disease | ||
| Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2) | Cytoplasm | ||
| Putative protein MSS51 homolog, mitochondrial (Zinc finger MYND domain-containing protein 17) | |||
| 26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27) | |||
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (Complex I-PDSW) (CI-PDSW) (NADH-ubiquinone oxidoreductase PDSW subunit) | Mitochondrion inner membrane | ||
| ER membrane protein complex subunit 6 (Transmembrane protein 93) | Membrane | ||
| ER membrane protein complex subunit 7 | Membrane | ||
| Decapping and exoribonuclease protein (DXO) (EC 3.1.13.-) (EC 3.6.1.-) (Dom-3 homolog Z) | Nucleus | ||
| Tectonic-2 | Membrane | ||
| LIM domain only protein 3 (LMO-3) (Neuronal-specific transcription factor DAT1) (Rhombotin-3) | |||
| Sodium channel modifier 1 | Nucleus, nucleoplasm | ||
| Tectonic-3 | Membrane | ||
| Transmembrane protein 237 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein) | lateral sclerosis | Membrane | |
| Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein) | multiple system atrophy | Cytoplasm | |
| ER membrane protein complex subunit 3 (Transmembrane protein 111) | Membrane | ||
| Emerin | Nucleus inner membrane | ||
| Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I) | |||
| Zinc finger protein 250 (Zinc finger protein 647) | Nucleus | ||
| SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2) | Nucleus. | ||
| B melanoma antigen 4 (Cancer/testis antigen 2.4) (CT2.4) | Secreted | ||
| Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 3.6.3.49) (cAMP-dependent chloride channel) | Apical cell membrane | ||
| RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca) | Cytoplasm | ||
| Lamin-B1 | multiple sclerosis | Nucleus inner membrane | |
| DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21) | Nucleus | ||
| Protein FAM90A1 | |||
| Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1) | Nucleus | ||
| U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5) | Nucleus | ||
| Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) | Late endosome | ||
| Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks) | |||
| Deleted in azoospermia protein 2 | Cytoplasm | ||
| EF-hand domain-containing family member C2 | |||
| AP-5 complex subunit mu-1 (Adaptor-related protein complex 5 subunit mu-1) (Mu5) (Mu-2-related death-inducing protein) (MuD) (Putative HIV-1 infection-related protein) | Cytoplasm, cytosol | ||
| Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin] | Cytoplasm | ||
| Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor (Urogastrone)] | Membrane | ||
| Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) | autosomal recessive cerebellar ataxia | Nucleus outer membrane | |
| Heat shock 70 kDa protein 1B (Heat shock 70 kDa protein 2) (HSP70-2) (HSP70.2) | Cytoplasm | ||
| U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD) | Nucleus | ||
| Protein argonaute-4 (Argonaute4) (hAgo4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4) | Cytoplasm, P-body | ||
| Hippocalcin-like protein 4 (HLP4) | |||
| Cadherin-13 (Heart cadherin) (H-cadherin) (P105) (Truncated cadherin) (T-cad) (T-cadherin) | Alzheimer disease lateral sclerosis multiple sclerosis | Cell membrane | |
| 14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed] | Cytoplasm | ||
| Neurocalcin-delta | |||
| DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460) | Nucleus | ||
| Visinin-like protein 1 (VILIP) (VLP-1) (Hippocalcin-like protein 3) (HLP3) | |||
| Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) | Nucleus | ||
| Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17) | Cytoplasm, cytoskeleton | ||
| F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1) | Nucleus | ||
| Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer) | Cytoplasm, P-body | ||
| Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain) | Cytoplasm, cytoskeleton. | ||
| Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56) | Isoform 1: Cell membrane | ||
| Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28) | Nucleus | ||
| Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) | olivopontocerebellar atrophy | Cell membrane | |
| Ras-related protein Rab-3A | Cell membrane | ||
| Suppressor of IKBKE 1 (Suppressor of IKK-epsilon) | Cytoplasm | ||
| Syntaxin-1B (Syntaxin-1B1) (Syntaxin-1B2) | Isoform 1: Membrane | ||
| Calretinin (CR) (29 kDa calbindin) | |||
| SUN domain-containing protein 2 (Protein unc-84 homolog B) (Rab5-interacting protein) (Rab5IP) (Sad1/unc-84 protein-like 2) | Nucleus inner membrane | ||
| LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1) | |||
| Ral GTPase-activating protein subunit beta (p170) | |||
| Tubulin alpha-1C chain (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain] | Cytoplasm, cytoskeleton. | ||
| SWI/SNF complex subunit SMARCC1 (BRG1-associated factor 155) (BAF155) (SWI/SNF complex 155 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1) | Nucleus | ||
| ATP-dependent RNA helicase DDX42 (EC 3.6.4.13) (DEAD box protein 42) (RNA helicase-like protein) (RHELP) (RNA helicase-related protein) (RNAHP) (SF3b DEAD box protein) (Splicing factor 3B-associated 125 kDa protein) (SF3b125) | |||
| Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin) | |||
| Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3) | Cytoplasm | ||
| Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4) | Cytoplasm | ||
| Nesprin-2 (KASH domain-containing protein 2) (KASH2) (Nuclear envelope spectrin repeat protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE) (Synaptic nuclear envelope protein 2) (Syne-2) | Nucleus outer membrane | ||
| Probable E3 ubiquitin-protein ligase HERC3 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 3) (HECT-type E3 ubiquitin transferase HERC3) | |||
| Endophilin-A1 (EEN-B1) (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2) | Cytoplasm | ||
| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (BRG1-associated factor 47) (BAF47) (Integrase interactor 1 protein) (SNF5 homolog) (hSNF5) | Nucleus. | ||
| Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III) | Cytoplasm, cytoskeleton. | ||
| Histone deacetylase complex subunit SAP130 (130 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p130) | Nucleus | ||
| Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit) | |||
| Zinc finger Ran-binding domain-containing protein 2 (Zinc finger protein 265) (Zinc finger, splicing) | Nucleus | ||
| Fanconi anemia group I protein (Protein FACI) | Nucleus | ||
| Fetal and adult testis-expressed transcript protein (Cancer/testis antigen 43) (CT43) (Tumor antigen BJ-HCC-2) | Mitochondrion | ||
| Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7) | |||
| Tripartite motif-containing protein 42 | |||
| Proto-oncogene vav | |||
| Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (hGAA1) | autosomal recessive cerebellar ataxia | Endoplasmic reticulum membrane | |
| Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed] | Cytoplasm | ||
| Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (2HOR0202) (Cell growth-inhibiting gene 38 protein) (Sin3-associated polypeptide p18) | Nucleus | ||
| Activator of basal transcription 1 (hABT1) (Basal transcriptional activator) | Nucleus | ||
| Spliceosome RNA helicase DDX39B (EC 3.6.4.13) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (DEAD box protein UAP56) (HLA-B-associated transcript 1 protein) | |||
| Developmental pluripotency-associated protein 4 | Nucleus | ||
| PHD finger protein 7 (Testis development protein NYD-SP6) | Nucleus | ||
| Polycomb protein SUZ12 (Chromatin precipitated E2F target 9 protein) (ChET 9 protein) (Joined to JAZF1 protein) (Suppressor of zeste 12 protein homolog) | Nucleus | ||
| Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 1) (HSP70-1) (HSP70.1) | Cytoplasm | ||
| Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 3) (NLI-IF) (NLI-interacting factor 3) (Small C-terminal domain phosphatase 1) (SCP1) (Small CTD phosphatase 1) | Nucleus | ||
| Dual specificity phosphatase DUPD1 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase 27) | Cytoplasm | ||
| Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1) | Cytoplasm | ||
| Lupus La protein (La autoantigen) (La ribonucleoprotein) (Sjoegren syndrome type B antigen) (SS-B) | Nucleus | ||
| Inositol-3-phosphate synthase 1 (IPS 1) (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase) (MI-1-P synthase) (MIP synthase) (hIPS) (Myo-inositol 1-phosphate synthase A1) (hINO1) | Cytoplasm | ||
| Germ cell-less protein-like 1 | Nucleus matrix | ||
| Solute carrier family 52, riboflavin transporter, member 1 (Porcine endogenous retrovirus A receptor 2) (PERV-A receptor 2) (Protein GPR172B) (Riboflavin transporter 1) (hRFT1) | Cell membrane | ||
| Tubulin beta chain (Tubulin beta-5 chain) | Cytoplasm, cytoskeleton | ||
| Tubulin beta-2A chain (Tubulin beta class IIa) | Cytoplasm, cytoskeleton | ||
| E3 ubiquitin-protein ligase TRIM69 (EC 2.3.2.27) (RFP-like domain-containing protein trimless) (RING finger protein 36) (RING-type E3 ubiquitin transferase TRIM69) (Tripartite motif-containing protein 69) | Cytoplasm | ||
| Barrier-to-autointegration factor (Breakpoint cluster region protein 1) [Cleaved into: Barrier-to-autointegration factor, N-terminally processed] | Barrier-to-autointegration factor: Nucleus | ||
| Tubulin alpha-1A chain (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain] | Cytoplasm, cytoskeleton. | ||
| EH domain-binding protein 1-like protein 1 | Endosome | ||
| Wilms tumor protein 1-interacting protein (WT1-interacting protein) | Cell junction, adherens junction | ||
| LIM domain-containing protein ajuba | |||
| Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2) | Cytoplasm | ||
| Gamma-tubulin complex component 2 (GCP-2) (hGCP2) (Gamma-ring complex protein 103 kDa) (h103p) (hGrip103) (Spindle pole body protein Spc97 homolog) (hSpc97) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Bystin | Cytoplasm | ||
| Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1) | Cytoplasm, cytosol | ||
| Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.4.19.12) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) | |||
| GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein) | Parkinson disease | ||
| Neuropathy target esterase (EC 3.1.1.5) (Patatin-like phospholipase domain-containing protein 6) | spastic ataxia | Endoplasmic reticulum membrane | |
| WW domain-binding protein 1 (WBP-1) | |||
| Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha) | |||
| Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) | Cytoplasm | ||
| Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117) | Isoform 1: Cell membrane | ||
| Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck) | |||
| Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn) | Cell membrane | ||
| Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Calsenilin-like protein) (Potassium channel-interacting protein 4) | Cell membrane | ||
| Platelet-derived growth factor receptor-like protein (PDGFR-like protein) (PDGF receptor beta-like tumor suppressor) | Secreted | ||
| Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1) | |||
| Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1) | Cytoplasm | ||
| Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk) | Cell membrane | ||
| Transcription factor PU.1 (31 kDa-transforming protein) | Nucleus | ||
| Vacuolar protein sorting-associated protein 52 homolog (SAC2 suppressor of actin mutations 2-like protein) | Golgi apparatus, trans-Golgi network membrane | ||
| Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1) | Isoform 2: Nucleus. | ||
| Protein FAM186B | |||
| WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box-containing WD protein SWiP-1) | |||
| Tripartite motif-containing protein 10 (B30-RING finger protein) (RING finger protein 9) | Cytoplasm | ||
| Protein FAM210B, mitochondrial | Mitochondrion | ||
| Procollagen galactosyltransferase 2 (EC 2.4.1.50) (Collagen beta(1-O)galactosyltransferase 2) (ColGalT 2) (Glycosyltransferase 25 family member 2) (Hydroxylysine galactosyltransferase 2) | Endoplasmic reticulum lumen | ||
| Transmembrane 4 L6 family member 20 | autism spectrum disorder | Membrane | |
| Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta) | Cytoplasm | ||
| Delta-sarcoglycan (Delta-SG) (35 kDa dystrophin-associated glycoprotein) (35DAG) | Cell membrane, sarcolemma | ||
| Caseinolytic peptidase B protein homolog (EC 3.6.1.3) (Suppressor of potassium transport defect 3) | Mitochondrion | ||
| Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (Fp) | Mitochondrion inner membrane | ||
| Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B-Val; Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)] | Lysosome | ||
| Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) | Cytoplasm | ||
| Coagulation factor XI (FXI) (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) [Cleaved into: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain] | Secreted. | ||
| Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain] | Secreted. | ||
| X-linked retinitis pigmentosa GTPase regulator | Cytoplasm, cytoskeleton, flagellum axoneme | ||
| Antithrombin-III (ATIII) (Serpin C1) | Secreted, extracellular space. | ||
| mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41) | Cytoplasm | ||
| Caspase-6 (CASP-6) (EC 3.4.22.59) (Apoptotic protease Mch-2) [Cleaved into: Caspase-6 subunit p18; Caspase-6 subunit p11] | Cytoplasm. | ||
| F-box/LRR-repeat protein 18 (F-box and leucine-rich repeat protein 18) | |||
| Protein FAM45A | |||
| RNA-binding protein 4 (Lark homolog) (hLark) (RNA-binding motif protein 4) (RNA-binding motif protein 4a) | |||
| E3 ubiquitin-protein ligase RNF168 (hRNF168) (EC 2.3.2.27) (RING finger protein 168) (RING-type E3 ubiquitin transferase RNF168) | Nucleus | ||
| Membrane-spanning 4-domains subfamily A member 4A (CD20 antigen-like 1) (Four-span transmembrane protein 1) | Membrane | ||
| Elongation factor 1-alpha 2 (EF-1-alpha-2) (Eukaryotic elongation factor 1 A-2) (eEF1A-2) (Statin-S1) | Nucleus | ||
| 60S acidic ribosomal protein P2 (Large ribosomal subunit protein P2) (Renal carcinoma antigen NY-REN-44) | |||
| Syntaxin-5 | Endoplasmic reticulum-Golgi intermediate compartment membrane | ||
| E3 ubiquitin-protein ligase RBX1 (EC 2.3.2.27) (EC 2.3.2.32) (E3 ubiquitin-protein transferase RBX1) (Protein ZYP) (RING finger protein 75) (RING-box protein 1) (Rbx1) (Regulator of cullins 1) (ROC1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed (E3 ubiquitin-protein transferase RBX1, N-terminally processed)] | Cytoplasm | ||
| Phytanoyl-CoA hydroxylase-interacting protein (Phytanoyl-CoA hydroxylase-associated protein 1) (PAHX-AP1) (PAHXAP1) | |||
| Macrophage migration inhibitory factor (MIF) (EC 5.3.2.1) (Glycosylation-inhibiting factor) (GIF) (L-dopachrome isomerase) (L-dopachrome tautomerase) (EC 5.3.3.12) (Phenylpyruvate tautomerase) | Secreted | ||
| Transmembrane protein 42 | Membrane | ||
| Elongation factor 2 (EF-2) | Cytoplasm | ||
| Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (Rubicon) (Beclin-1 associated RUN domain containing protein) (Baron) | autosomal recessive cerebellar ataxia | Late endosome | |
| Actin-related protein 5 (hARP5) (Sarcoma antigen NY-SAR-16) | Nucleus | ||
| Polyamine-modulated factor 1 (PMF-1) | Nucleus | ||
| WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2) | Preautophagosomal structure membrane | ||
| DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe) | |||
| Growth arrest and DNA damage-inducible proteins-interacting protein 1 (39S ribosomal protein L59, mitochondrial) (MRP-L59) (CKII beta-associating protein) (CR6-interacting factor 1) (CRIF1) (Mitochondrial large ribosomal subunit protein mL64) (Papillomavirus L2-interacting nuclear protein 1) (PLINP) (PLINP-1) (p53-responsive gene 6 protein) | Mitochondrion | ||
| 60S ribosomal protein L38 (Large ribosomal subunit protein eL38) | |||
| 40S ribosomal protein S29 (Small ribosomal subunit protein uS14) | Cytoplasm, cytosol | ||
| Heterogeneous nuclear ribonucleoprotein D-like (hnRNP D-like) (hnRNP DL) (AU-rich element RNA-binding factor) (JKT41-binding protein) (Protein laAUF1) | Nucleus | ||
| Zinc finger matrin-type protein 2 | Nucleus | ||
| tRNA-splicing endonuclease subunit Sen15 (SEN15 homolog) (HsSEN15) (tRNA-intron endonuclease Sen15) | pontocerebellar hypoplasia | Nucleus | |
| Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) | Alzheimer disease | Membrane | |
| Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog) | X-linked hereditary ataxia autism spectrum disorder autosomal dominant cerebellar ataxia | Cytoplasm | |
| Selenocysteine lyase (hSCL) (EC 4.4.1.16) | Cytoplasm, cytosol | ||
| Peroxiredoxin-1 (EC 1.11.1.15) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) | Alzheimer disease | Cytoplasm | |
| Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68) | Nucleus, nucleolus | ||
| Nucleolysin TIAR (TIA-1-related protein) | Cytoplasm | ||
| Tumor protein 63 (p63) (Chronic ulcerative stomatitis protein) (CUSP) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) (p40) (p51) | Nucleus | ||
| Transmembrane protein 144 | Membrane | ||
| Protein FAM104A | |||
| Coiled-coil domain-containing protein 57 | |||
| DNA polymerase delta catalytic subunit (EC 2.7.7.7) (EC 3.1.11.-) (DNA polymerase subunit delta p125) | Nucleus | ||
| 60S ribosomal protein L8 (Large ribosomal subunit protein uL2) | Cytoplasm | ||
| Fibrinogen gamma chain | Secreted | ||
| Ferrochelatase, mitochondrial (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase) | Mitochondrion inner membrane | ||
| Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) (Viral integration site protein INT-6 homolog) (eIF-3 p48) | Cytoplasm | ||
| Receptor expression-enhancing protein 6 (Polyposis locus protein 1-like 1) | Endoplasmic reticulum membrane | ||
| Protein Hook homolog 1 (h-hook1) (hHK1) | Cytoplasm | ||
| Endothelin-1 (Preproendothelin-1) (PPET1) [Cleaved into: Endothelin-1 (ET-1); Big endothelin-1] | Parkinson disease | Secreted. | |
| Protein FAM124B | Nucleus | ||
| 60S ribosomal protein L6 (Large ribosomal subunit protein eL6) (Neoplasm-related protein C140) (Tax-responsive enhancer element-binding protein 107) (TaxREB107) | Cytoplasm, cytosol | ||
| Baculoviral IAP repeat-containing protein 7 (EC 2.3.2.27) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) (RING-type E3 ubiquitin transferase BIRC7) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)] | Nucleus | ||
| Ubiquitin-40S ribosomal protein S27a (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; 40S ribosomal protein S27a (Small ribosomal subunit protein eS31)] | Ubiquitin: Cytoplasm | ||
| Protein FAM170A (Zinc finger domain-containing protein) (Zinc finger protein ZNFD) | Nucleus | ||
| 40S ribosomal protein S15a (Small ribosomal subunit protein uS8) | |||
| La-related protein 4 (La ribonucleoprotein domain family member 4) | Cytoplasm, Stress granule | ||
| Heat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom) | |||
| Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein) | Endoplasmic reticulum lumen | ||
| Armadillo repeat-containing X-linked protein 3 (ARM protein lost in epithelial cancers on chromosome X 3) (Protein ALEX3) | Mitochondrion outer membrane | ||
| H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7) | Lysosome membrane | ||
| Uncharacterized protein C4orf17 | |||
| Teratocarcinoma-derived growth factor 1 (Cripto-1 growth factor) (CRGF) (Epidermal growth factor-like cripto protein CR1) | Cell membrane | ||
| G-patch domain and KOW motifs-containing protein (G-patch domain-containing protein 5) (Protein MOS2 homolog) (Protein T54) | Nucleus | ||
| 60S ribosomal protein L4 (60S ribosomal protein L1) (Large ribosomal subunit protein uL4) | |||
| Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1) | Nucleus, nucleoplasm | ||
| Protein FAM187B (Transmembrane protein 162) | Membrane | ||
| ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (Helicase-like protein 2) (HLP2) | |||
| U1 small nuclear ribonucleoprotein C (U1 snRNP C) (U1-C) (U1C) | Nucleus | ||
| 60S ribosomal protein L23 (60S ribosomal protein L17) (Large ribosomal subunit protein uL14) | |||
| Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed] | autism spectrum disorder | Nucleus, nucleoplasm. | |
| Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] | Cytoplasm. | ||
| 60S ribosomal protein L24 (60S ribosomal protein L30) (Large ribosomal subunit protein eL24) | |||
| Kininogen-1 (Alpha-2-thiol proteinase inhibitor) (Fitzgerald factor) (High molecular weight kininogen) (HMWK) (Williams-Fitzgerald-Flaujeac factor) [Cleaved into: Kininogen-1 heavy chain; T-kinin (Ile-Ser-Bradykinin); Bradykinin (Kallidin I); Lysyl-bradykinin (Kallidin II); Kininogen-1 light chain; Low molecular weight growth-promoting factor] | Secreted, extracellular space. | ||
| 40S ribosomal protein S20 (Small ribosomal subunit protein uS10) | Cytoplasm | ||
| Rhomboid domain-containing protein 3 | Membrane | ||
| 60S ribosomal protein L11 (CLL-associated antigen KW-12) (Large ribosomal subunit protein uL5) | Nucleus, nucleolus | ||
| 60S ribosomal protein L31 (Large ribosomal subunit protein eL31) | |||
| Rhomboid-related protein 4 (RRP4) (EC 3.4.21.105) (Rhomboid domain-containing protein 1) (Rhomboid-like protein 4) | Membrane | ||
| Calpain-15 (EC 3.4.22.-) (Small optic lobes homolog) | |||
| Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1) | Nucleus | ||
| CDK-activating kinase assembly factor MAT1 (CDK7/cyclin-H assembly factor) (Cyclin-G1-interacting protein) (Menage a trois) (RING finger protein 66) (RING finger protein MAT1) (p35) (p36) | Nucleus. | ||
| Kelch-like protein 15 | Nucleus | ||
| COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15) | Cytoplasm | ||
| Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5) | Nucleus | ||
| Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) | Nucleus | ||
| Heterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed] | Nucleus, nucleoplasm. | ||
| Calcium-binding protein 8 (CaBP8) (Calneuron I) (Calneuron-1) | Golgi apparatus, trans-Golgi network membrane | ||
| DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog) | |||
| Protein FAM221A | |||
| Protein FAM222B | |||
| Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Tumor rejection antigen 1) (gp96 homolog) | |||
| Integral membrane protein 2B (Immature BRI2) (imBRI2) (Protein E25B) (Transmembrane protein BRI) (Bri) [Cleaved into: BRI2, membrane form (Mature BRI2) (mBRI2); BRI2 intracellular domain (BRI2 ICD); BRI2C, soluble form; Bri23 peptide (Bri2-23) (ABri23) (C-terminal peptide) (P23 peptide)] | spastic ataxia autosomal dominant cerebellar ataxia | Integral membrane protein 2B: Golgi apparatus membrane | |
| 40S ribosomal protein S14 (Small ribosomal subunit protein uS11) | |||
| EP300-interacting inhibitor of differentiation 2B (EID-2B) (EID-2-like inhibitor of differentiation 3) (EID-3) | Nucleus | ||
| Melanoma-associated antigen E1 (Alpha-dystrobrevin-associated MAGE Protein) (DAMAGE) (Hepatocellular carcinoma-associated protein 1) (MAGE-E1 antigen) | autism spectrum disorder | Cytoplasm, perinuclear region | |
| DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA) | Nucleus | ||
| Caspase-8 (CASP-8) (EC 3.4.22.61) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) (FADD-homologous ICE/ced-3-like protease) (FADD-like ICE) (FLICE) (ICE-like apoptotic protease 5) (MORT1-associated ced-3 homolog) (MACH) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10] | lateral sclerosis multiple sclerosis | Cytoplasm. | |
| Keratin, type II cytoskeletal 75 (Cytokeratin-75) (CK-75) (Keratin-6 hair follicle) (hK6hf) (Keratin-75) (K75) (Type II keratin-K6hf) (Type-II keratin Kb18) | |||
| Nuclear pore complex protein Nup133 (133 kDa nucleoporin) (Nucleoporin Nup133) | Nucleus, nuclear pore complex | ||
| Forkhead box protein I1 (Forkhead-related protein FKHL10) (Forkhead-related transcription factor 6) (FREAC-6) (Hepatocyte nuclear factor 3 forkhead homolog 3) (HFH-3) (HNF-3/fork-head homolog 3) | Nucleus. | ||
| Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-) | Cytoplasm, cytosol | ||
| F-box only protein 17 (F-box only protein 26) | |||
| Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.4.19.12) (Deubiquitinating enzyme 21) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) | Cytoplasm | ||
| E3 ubiquitin-protein ligase Praja-1 (Praja1) (EC 2.3.2.27) (RING finger protein 70) (RING-type E3 ubiquitin transferase Praja-1) | |||
| 40S ribosomal protein S4, X isoform (SCR10) (Single copy abundant mRNA protein) (Small ribosomal subunit protein eS4) | Cytoplasm | ||
| Survival motor neuron protein (Component of gems 1) (Gemin-1) | spinal muscular atrophy | Nucleus, gem | |
| Solute carrier family 2, facilitated glucose transporter member 1 (Glucose transporter type 1, erythrocyte/brain) (GLUT-1) (HepG2 glucose transporter) | episodic ataxia spastic ataxia | ||
| Platelet-activating factor acetylhydrolase IB subunit gamma (EC 3.1.1.47) (PAF acetylhydrolase 29 kDa subunit) (PAF-AH 29 kDa subunit) (PAF-AH subunit gamma) (PAFAH subunit gamma) | Cytoplasm. | ||
| V-type proton ATPase subunit H (V-ATPase subunit H) (Nef-binding protein 1) (NBP1) (Protein VMA13 homolog) (V-ATPase 50/57 kDa subunits) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD) | |||
| Enhancer of rudimentary homolog | |||
| Protein eva-1 homolog B (Protein FAM176B) | Membrane | ||
| DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB) | Nucleus | ||
| Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit) | Nucleus, nucleoplasm. | ||
| Zinc finger protein 41 homolog (Zfp-41) | Nucleus | ||
| Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein) | Nucleus | ||
| Sperm acrosome membrane-associated protein 4 (Sperm acrosomal membrane-associated protein 14) | Cell membrane | ||
| Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG) | Cytoplasm, cytosol | ||
| Polyubiquitin-B [Cleaved into: Ubiquitin] | Ubiquitin: Cytoplasm | ||
| RNA-binding protein 24 (RNA-binding motif protein 24) (RNA-binding region-containing protein 6) | Nucleus | ||
| Glycodelin (GD) (Placental protein 14) (PP14) (Pregnancy-associated endometrial alpha-2 globulin) (PAEG) (PEG) (Progestagen-associated endometrial protein) (Progesterone-associated endometrial protein) (Zona-binding inhibitory factor-1) (ZIF-1) | Secreted | ||
| Ubiquitin-like protein FUBI | |||
| TATA-binding protein-associated factor 2N (68 kDa TATA-binding protein-associated factor) (TAF(II)68) (TAFII68) (RNA-binding protein 56) | Nucleus | ||
| Zinc finger and SCAN domain-containing protein 20 (Zinc finger protein 31) (Zinc finger protein 360) (Zinc finger protein KOX29) | Nucleus | ||
| Sorting nexin-4 | Early endosome | ||
| Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (Sm-D autoantigen) (snRNP core protein D1) | Cytoplasm, cytosol | ||
| FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-) | Parkinson disease | Mitochondrion inner membrane | |
| 14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin) | Cytoplasm | ||
| Calcium and integrin-binding protein 1 (CIB) (Calcium- and integrin-binding protein) (CIBP) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP) (SNK-interacting protein 2-28) (SIP2-28) | |||
| DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23) | |||
| Chondroitin sulfate synthase 2 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 2) (Chondroitin-polymerizing factor) (ChPF) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (N-acetylgalactosaminyltransferase 2) | Isoform 1: Golgi apparatus, Golgi stack membrane | ||
| Phosphatidylcholine-sterol acyltransferase (EC 2.3.1.43) (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase) | Secreted | ||
| Retinol-binding protein 3 (Interphotoreceptor retinoid-binding protein) (IRBP) (Interstitial retinol-binding protein) | |||
| Interferon regulatory factor 5 (IRF-5) | |||
| F-box only protein 7 | Parkinson disease | ||
| Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like protein mcs94-1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein F, N-terminally processed] | Nucleus, nucleoplasm. | ||
| Stabilizer of axonemal microtubules 1 | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole | ||
| Late cornified envelope protein 2B (Late envelope protein 10) (Skin-specific protein Xp5) (Small proline-rich-like epidermal differentiation complex protein 1B) | |||
| Rab-3A-interacting protein (Rab3A-interacting protein) (Rabin-3) (SSX2-interacting protein) | |||
| Kelch-like protein 8 | |||
| cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI) | Cytoplasm | ||
| Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat-containing gene 10 protein) | Nucleus | ||
| Metaxin-2 (Mitochondrial outer membrane import complex protein 2) | Mitochondrion outer membrane | ||
| BTB/POZ domain-containing protein KCTD7 | Cell membrane | ||
| TBC1 domain family member 23 (HCV non-structural protein 4A-transactivated protein 1) | pontocerebellar hypoplasia | Golgi apparatus, trans-Golgi network | |
| Heme oxygenase 2 (HO-2) (EC 1.14.14.18) | Microsome | ||
| Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) | Cytoplasm | ||
| Protein S100-A10 (Calpactin I light chain) (Calpactin-1 light chain) (Cellular ligand of annexin II) (S100 calcium-binding protein A10) (p10 protein) (p11) | |||
| Melanoma antigen preferentially expressed in tumors (Opa-interacting protein 4) (OIP-4) (Preferentially expressed antigen of melanoma) | Nucleus | ||
| Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (APOBEC1-binding protein 1) (ABBP-1) | Nucleus | ||
| BRISC and BRCA1-A complex member 1 (Mediator of RAP80 interactions and targeting subunit of 40 kDa) (New component of the BRCA1-A complex) | Cytoplasm | ||
| RNA-binding protein 14 (Paraspeckle protein 2) (PSP2) (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein) | Nucleus | ||
| Bifunctional purine biosynthesis protein PURH [Cleaved into: Bifunctional purine biosynthesis protein PURH, N-terminally processed] [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)] | |||
| NEDD8-conjugating enzyme Ubc12 (EC 2.3.2.-) (NEDD8 carrier protein) (Ubiquitin-conjugating enzyme E2 M) | |||
| 60S ribosomal protein L18 (Large ribosomal subunit protein eL18) | Cytoplasm, cytosol | ||
| Nucleolin (Protein C23) | |||
| Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) | Secreted | ||
| Fibulin-2 (FIBL-2) | Secreted, extracellular space, extracellular matrix. | ||
| Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase) | Mitochondrion inner membrane. | ||
| Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1) | Isoform Alpha: Cytoplasm | ||
| Vimentin | Cytoplasm | ||
| Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein) | |||
| Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (CMH-1) (ICE-like apoptotic protease 3) (ICE-LAP3) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11] | Cytoplasm. | ||
| BTB/POZ domain-containing protein KCTD3 (Renal carcinoma antigen NY-REN-45) | Cell membrane | ||
| Kelch-like protein 42 (Cullin-3-binding protein 9) (Ctb9) (Kelch domain-containing protein 5) | Cytoplasm | ||
| Annex |