| Entry name | Protein name | Involved in ND | Subcellular location |
|---|---|---|---|
| BolA-like protein 1 (hBolA) | Mitochondrion | ||
| Filamin-binding LIM protein 1 (FBLP-1) (Migfilin) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) | Cell junction, focal adhesion | ||
| Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1) | |||
| DNA mismatch repair protein Mlh1 (MutL protein homolog 1) | Nucleus | ||
| Ceruloplasmin (EC 1.16.3.1) (Ferroxidase) | |||
| Apolipoprotein A-I (Apo-AI) (ApoA-I) (Apolipoprotein A1) [Cleaved into: Proapolipoprotein A-I (ProapoA-I); Truncated apolipoprotein A-I (Apolipoprotein A-I(1-242))] | Secreted. | ||
| Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase) | Nucleus | ||
| NADH-cytochrome b5 reductase 3 (B5R) (Cytochrome b5 reductase) (EC 1.6.2.2) (Diaphorase-1) [Cleaved into: NADH-cytochrome b5 reductase 3 membrane-bound form; NADH-cytochrome b5 reductase 3 soluble form] | Isoform 1: Endoplasmic reticulum membrane | ||
| 2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase) | Mitochondrion matrix | ||
| Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1) | Nucleus | ||
| Potassium voltage-gated channel subfamily A member 2 (NGK1) (Voltage-gated K(+) channel HuKIV) (Voltage-gated potassium channel HBK5) (Voltage-gated potassium channel subunit Kv1.2) | Cell membrane | ||
| B-cell lymphoma 6 protein (BCL-6) (B-cell lymphoma 5 protein) (BCL-5) (Protein LAZ-3) (Zinc finger and BTB domain-containing protein 27) (Zinc finger protein 51) | Nucleus | ||
| Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Neuroligin-3 (Gliotactin homolog) | autism spectrum disorder | Cell membrane | |
| Nucleolar protein 56 (Nucleolar protein 5A) | Nucleus, nucleolus | ||
| Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin) | progressive muscular atrophy | Cytoplasm | |
| Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13) | Nucleus. | ||
| Inward rectifier potassium channel 2 (Cardiac inward rectifier potassium channel) (Inward rectifier K(+) channel Kir2.1) (IRK-1) (hIRK1) (Potassium channel, inwardly rectifying subfamily J member 2) | Membrane | ||
| Glutamate receptor 3 (GluR-3) (AMPA-selective glutamate receptor 3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (GluA3) | |||
| 5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A) | Cell membrane | ||
| Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) | Cytoplasm | ||
| DENN domain-containing protein 4B | Golgi apparatus | ||
| Nitric oxide synthase, brain (EC 1.14.13.39) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Peptidyl-cysteine S-nitrosylase NOS1) (bNOS) | Cell membrane, sarcolemma | ||
| DNA polymerase epsilon subunit 3 (EC 2.7.7.7) (Arsenic-transactivated protein) (AsTP) (Chromatin accessibility complex 17 kDa protein) (CHRAC-17) (HuCHRAC17) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17) | Nucleus | ||
| Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1) (p38) | Cytoplasm, cytosol | ||
| Potassium voltage-gated channel subfamily A member 5 (HPCN1) (Voltage-gated potassium channel HK2) (Voltage-gated potassium channel subunit Kv1.5) | Cell membrane | ||
| Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46) | Lysosome membrane | ||
| Neuroligin-4, X-linked (Neuroligin X) (HNLX) | autism spectrum disorder | Cell membrane | |
| Glutamate receptor ionotropic, kainate 1 (GluK1) (Excitatory amino acid receptor 3) (EAA3) (Glutamate receptor 5) (GluR-5) (GluR5) | Cell membrane | ||
| Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor) | Nucleus | ||
| Coiled-coil domain-containing protein 173 | |||
| RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3) | Nucleus | ||
| Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1) | autism spectrum disorder | ||
| Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1) | Isoform BIN1: Nucleus | ||
| Cullin-4B (CUL-4B) | Nucleus | ||
| Potassium voltage-gated channel subfamily A member 1 (Voltage-gated K(+) channel HuKI) (Voltage-gated potassium channel HBK1) (Voltage-gated potassium channel subunit Kv1.1) | episodic ataxia | Cell membrane | |
| Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114) | Nucleus | ||
| Insulin-induced gene 2 protein (INSIG-2) | Endoplasmic reticulum membrane | ||
| Caveolin-3 (M-caveolin) | progressive muscular atrophy | Golgi apparatus membrane | |
| Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3) | agenesis of the corpus callosum with peripheral neuropathy | Basolateral cell membrane | |
| Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55) | Endoplasmic reticulum | ||
| Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7) | Nucleus | ||
| Telethonin (Titin cap protein) | Cytoplasm, myofibril, sarcomere | ||
| Multiple PDZ domain protein (Multi-PDZ domain protein 1) | |||
| Heterogeneous nuclear ribonucleoprotein M (hnRNP M) | Nucleus, nucleolus | ||
| F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4) | Isoform 1: Nucleus, nucleoplasm | ||
| Annexin A1 (Annexin I) (Annexin-1) (Calpactin II) (Calpactin-2) (Chromobindin-9) (Lipocortin I) (Phospholipase A2 inhibitory protein) (p35) | Nucleus | ||
| Proteasome adapter and scaffold protein ECM29 (Ecm29 proteasome adapter and scaffold) (Proteasome-associated protein ECM29 homolog) | Endoplasmic reticulum | ||
| Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74) | Mitochondrion | ||
| SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1) | Cytoplasm | ||
| Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta) | |||
| Pogo transposable element with ZNF domain (Suppressor of hairy wing homolog 5) (Zinc finger protein 280E) (Zinc finger protein 635) | autism spectrum disorder | ||
| rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (34 kDa nucleolar scleroderma antigen) (Histone-glutamine methyltransferase) | Nucleus, nucleolus | ||
| Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen) | Nucleus | ||
| Cullin-2 (CUL-2) | |||
| Ubiquitin-conjugating enzyme E2 variant 2 (DDVit 1) (Enterocyte differentiation-associated factor 1) (EDAF-1) (Enterocyte differentiation-promoting factor 1) (EDPF-1) (MMS2 homolog) (Vitamin D3-inducible protein) | |||
| Ubiquitin-conjugating enzyme E2 K (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase) | Cytoplasm | ||
| Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr) | Mitochondrion matrix | ||
| 5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein) | Nucleus, nucleolus | ||
| Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)] | Cytoplasm. | ||
| Protein ELYS (Embryonic large molecule derived from yolk sac) (Protein MEL-28) (Putative AT-hook-containing transcription factor 1) | Cytoplasm | ||
| Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase) | |||
| Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2) | Mitochondrion outer membrane | ||
| Glutamine-rich protein 1 | |||
| Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4) | |||
| Zinc finger CCCH domain-containing protein 11A | |||
| Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3) | Cell membrane | ||
| Nuclear migration protein nudC (Nuclear distribution protein C homolog) | |||
| Transcriptional enhancer factor TEF-5 (DTEF-1) (TEA domain family member 3) (TEAD-3) | Nucleus. | ||
| Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) (Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator) | Endoplasmic reticulum membrane | ||
| Gastrin-releasing peptide (GRP) [Cleaved into: Neuromedin-C (GRP-10)] | Secreted | ||
| Centrosome-associated protein CEP250 (250 kDa centrosomal protein) (Cep250) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Centrosomal protein 2) | Cytoplasm, perinuclear region | ||
| Lamin-B receptor (Integral nuclear envelope inner membrane protein) (LMN2R) | Nucleus inner membrane | ||
| Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1) | Nucleus | ||
| Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PP-T) (PPT) | Alzheimer disease | Nucleus | |
| GPI inositol-deacylase (EC 3.1.-.-) (Post-GPI attachment to proteins factor 1) (hPGAP1) | Endoplasmic reticulum membrane | ||
| COMM domain-containing protein 6 | Nucleus | ||
| Synaptotagmin-12 (Synaptotagmin XII) (SytXII) | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane | ||
| Vacuolar protein sorting-associated protein 26B (Vesicle protein sorting 26B) | Cytoplasm | ||
| Histone-lysine N-methyltransferase EZH1 (EC 2.1.1.43) (ENX-2) (Enhancer of zeste homolog 1) | Nucleus | ||
| Heat shock transcription factor, Y-linked (Heat shock transcription factor 2-like protein) (HSF2-like) | Nucleus | ||
| m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS) | |||
| Jupiter microtubule associated homolog 1 (Androgen-regulated protein 2) (Hematological and neurological expressed 1 protein) [Cleaved into: Jupiter microtubule associated homolog 1, N-terminally processed] | Nucleus | ||
| Scavenger receptor class A member 3 (Cellular stress response gene protein) | Endoplasmic reticulum membrane | ||
| Prolyl endopeptidase (PE) (EC 3.4.21.26) (Post-proline cleaving enzyme) | Cytoplasm. | ||
| Phenylalanine--tRNA ligase, mitochondrial (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase) (PheRS) | Mitochondrion matrix | ||
| Elongation factor 1-beta (EF-1-beta) | |||
| Nuclear protein localization protein 4 homolog (Protein NPL4) | Cytoplasm, cytosol | ||
| Oxysterol-binding protein-related protein 3 (ORP-3) (OSBP-related protein 3) | Endoplasmic reticulum membrane | ||
| Nuclear protein MDM1 | Nucleus | ||
| Netrin-4 (Beta-netrin) (Hepar-derived netrin-like protein) | Secreted, extracellular space, extracellular matrix, basement membrane | ||
| Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase) | Cytoplasm, cytoskeleton | ||
| RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha) | Cytoplasm | ||
| Cytochrome b5 type B (Cytochrome b5 outer mitochondrial membrane isoform) | Mitochondrion outer membrane | ||
| Proteasome subunit beta type-8 (EC 3.4.25.1) (Low molecular mass protein 7) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13) (Proteasome component C13) (Proteasome subunit beta-5i) (Really interesting new gene 10 protein) | Cytoplasm | ||
| Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1) | Nucleus. | ||
| Protein NipSnap homolog 1 (NipSnap1) | |||
| Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2) | Cytoplasm | ||
| Keratin-associated protein 15-1 | |||
| AP-4 complex subunit mu-1 (AP-4 adaptor complex mu subunit) (Adaptor-related protein complex 4 subunit mu-1) (Mu subunit of AP-4) (Mu-adaptin-related protein 2) (mu-ARP2) (Mu4-adaptin) (mu4) | Golgi apparatus, trans-Golgi network membrane | ||
| Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (A-SCS) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA) | Mitochondrion | ||
| Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (NFATx) (T-cell transcription factor NFAT4) (NF-AT4) | Cytoplasm | ||
| Uncharacterized protein C9orf43 | |||
| Nucleosome assembly protein 1-like 4 (Nucleosome assembly protein 2) (NAP-2) | Nucleus | ||
| Oxidoreductase HTATIP2 (EC 1.1.1.-) (30 kDa HIV-1 TAT-interacting protein) (HIV-1 TAT-interactive protein 2) | Cytoplasm | ||
| Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM-protein 1) (SLIM) (SLIM-1) | progressive muscular atrophy | Isoform 1: Cytoplasm. | |
| Fructose-bisphosphate aldolase A (EC 4.1.2.13) (Lung cancer antigen NY-LU-1) (Muscle-type aldolase) | |||
| Cullin-1 (CUL-1) | |||
| FAS-associated factor 2 (Protein ETEA) (UBX domain-containing protein 3B) (UBX domain-containing protein 8) | Cytoplasm | ||
| X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6) | Nucleus | ||
| M-phase phosphoprotein 8 (Two hybrid-associated protein 3 with RanBPM) (Twa3) | Nucleus | ||
| Ribonuclease P protein subunit p20 (RNaseP protein p20) (EC 3.1.26.5) (Ribonucleases P/MRP protein subunit POP7 homolog) (hPOP7) | Nucleus, nucleolus | ||
| Death effector domain-containing protein (DEDPro1) (Death effector domain-containing testicular molecule) (FLDED-1) | Cytoplasm | ||
| Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC) | Cytoplasm, cytoskeleton | ||
| Unconventional myosin-VI (Unconventional myosin-6) | Golgi apparatus, trans-Golgi network membrane | ||
| Cytosolic Fe-S cluster assembly factor NUBP2 (Nucleotide-binding protein 2) (NBP 2) | Nucleus | ||
| Mitochondrial-processing peptidase subunit beta (EC 3.4.24.64) (Beta-MPP) (P-52) | autosomal recessive cerebellar ataxia | Mitochondrion matrix | |
| Bone morphogenetic protein 4 (BMP-4) (Bone morphogenetic protein 2B) (BMP-2B) | Secreted, extracellular space, extracellular matrix. | ||
| Metabotropic glutamate receptor 4 (mGluR4) | Cell membrane | ||
| Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit] | |||
| Lysosomal thioesterase PPT2 (PPT-2) (EC 3.1.2.-) (S-thioesterase G14) | Lysosome | ||
| Hemogen (Erythroid differentiation-associated gene protein) (EDAG-1) (Hemopoietic gene protein) (Negative differentiation regulator protein) | Nucleus | ||
| Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-) | Cytoplasm | ||
| DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194) | Nucleus, nucleolus | ||
| Gamma-sarcoglycan (Gamma-SG) (35 kDa dystrophin-associated glycoprotein) (35DAG) | Cell membrane, sarcolemma | ||
| Protein SCO1 homolog, mitochondrial | Mitochondrion | ||
| DNA-directed RNA polymerase III subunit RPC7 (RNA polymerase III subunit C7) (DNA-directed RNA polymerase III subunit G) (RNA polymerase III 32 kDa apha subunit) (RPC32-alpha) (RNA polymerase III 32 kDa subunit) (RPC32) | Nucleus | ||
| Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1) | |||
| Trafficking protein particle complex subunit 2 (Sedlin) | Cytoplasm, perinuclear region | ||
| Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210) | Isoform 1: Endoplasmic reticulum-Golgi intermediate compartment | ||
| EKC/KEOPS complex subunit LAGE3 (L antigen family member 3) (Protein ESO-3) (Protein ITBA2) | Cytoplasm | ||
| DNA replication licensing factor MCM5 (EC 3.6.4.12) (CDC46 homolog) (P1-CDC46) | Nucleus | ||
| 14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1) | |||
| Renin receptor (ATPase H(+)-transporting lysosomal accessory protein 2) (ATPase H(+)-transporting lysosomal-interacting protein 2) (ER-localized type I transmembrane adaptor) (Embryonic liver differentiation factor 10) (N14F) (Renin/prorenin receptor) (Vacuolar ATP synthase membrane sector-associated protein M8-9) (ATP6M8-9) (V-ATPase M8.9 subunit) | Membrane | ||
| U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm) | Cytoplasm | ||
| Zinc finger protein-like 1 (Zinc finger protein MCG4) | Golgi apparatus, cis-Golgi network membrane | ||
| ATP synthase-coupling factor 6, mitochondrial (ATPase subunit F6) (ATP synthase peripheral stalk subunit F6) | Mitochondrion | ||
| MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1) | Isoform 2: Cytoplasm. | ||
| 85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9) | Parkinson disease | ||
| Neugrin (Mesenchymal stem cell protein DSC92) (Neurite outgrowth-associated protein) (Spinal cord-derived protein FI58G) | Nucleus | ||
| RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7) | |||
| Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1) | |||
| Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin-1) | spastic ataxia | Isoform 1: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane | |
| Acetylcholinesterase (AChE) (EC 3.1.1.7) | Cell junction, synapse | ||
| Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G) | Cytoplasm, cytoskeleton | ||
| Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)] | Nucleus | ||
| Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8) | Cytoplasm, cytoskeleton | ||
| Peptidyl-prolyl cis-trans isomerase FKBP2 (PPIase FKBP2) (EC 5.2.1.8) (13 kDa FK506-binding protein) (13 kDa FKBP) (FKBP-13) (FK506-binding protein 2) (FKBP-2) (Immunophilin FKBP13) (Rotamase) | Endoplasmic reticulum membrane | ||
| WD repeat-containing protein 81 | Early endosome membrane | ||
| Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (hOTU1) (Ubiquitin-specific-processing protease OTUB1) | Cytoplasm | ||
| Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein) | |||
| Putative ribosome-binding factor A, mitochondrial | Mitochondrion | ||
| F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit) | Cytoplasm | ||
| Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance regulatory protein ICln) (I(Cln)) (Chloride ion current inducer protein) (ClCI) (Reticulocyte pICln) | Cytoplasm, cytosol | ||
| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57) (BAF57) | Nucleus | ||
| Kinesin-like protein KIF1C | autosomal recessive cerebellar ataxia spastic ataxia | Cytoplasm, cytoskeleton | |
| Influenza virus NS1A-binding protein (NS1-BP) (NS1-binding protein) (Aryl hydrocarbon receptor-associated protein 3) (Kelch-like protein 39) | Cytoplasm | ||
| H/ACA ribonucleoprotein complex non-core subunit NAF1 (hNAF1) | |||
| Uncharacterized protein MISP3 (MISP family member 3) | |||
| Syntaxin-6 | Golgi apparatus membrane | ||
| Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101) | Cytoplasm | ||
| Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A) | Mitochondrion outer membrane | ||
| Telomerase reverse transcriptase (EC 2.7.7.49) (HEST2) (Telomerase catalytic subunit) (Telomerase-associated protein 2) (TP2) | Nucleus, nucleolus | ||
| Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Renal carcinoma antigen NY-REN-42) | Cytoplasm | ||
| Sulfite oxidase, mitochondrial (EC 1.8.3.1) | Mitochondrion intermembrane space. | ||
| Unconventional myosin-Ie (Myosin-Ic) (Unconventional myosin 1E) | multiple sclerosis | Cytoplasm | |
| Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) | Cytoplasm | ||
| T-cell surface glycoprotein CD4 (T-cell surface antigen T4/Leu-3) (CD antigen CD4) | Cell membrane | ||
| Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2) | Secreted. | ||
| Catalase (EC 1.11.1.6) | Peroxisome. | ||
| Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase (EC 4.2.1.17) (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)] | Peroxisome. | ||
| Protein SET (HLA-DR-associated protein II) (Inhibitor of granzyme A-activated DNase) (IGAAD) (PHAPII) (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I) | |||
| Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1) | Cytoplasm | ||
| Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l) | Nucleus | ||
| Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 2) (Neural enolase) (Neuron-specific enolase) (NSE) | Cytoplasm | ||
| Small ubiquitin-related modifier 4 (SUMO-4) (Small ubiquitin-like protein 4) | |||
| B-cell receptor-associated protein 31 (BCR-associated protein 31) (Bap31) (6C6-AG tumor-associated antigen) (Protein CDM) (p28) | Endoplasmic reticulum membrane | ||
| Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12) (Deubiquitinating enzyme 20) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (VHL-interacting deubiquitinating enzyme 2) (hVDU2) | Cytoplasm, perinuclear region | ||
| Syntaxin-2 (Epimorphin) | Membrane | ||
| Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH) | Nucleus | ||
| Fanconi anemia group A protein (Protein FACA) | |||
| Deleted in autism protein 1 (Golgi Protein of 49 kDa) (GoPro49) (Hypoxia and AKT-induced stem cell factor) (HASF) | autism spectrum disorder | Cytoplasmic vesicle, COPI-coated vesicle | |
| Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35) | Parkinson disease | Cytoplasm | |
| F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2) | Cytoplasm | ||
| ER membrane protein complex subunit 1 | multiple system atrophy | Membrane | |
| TOMM20-like protein 1 | Mitochondrion outer membrane | ||
| Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) (Muscle form hexokinase) | Mitochondrion outer membrane | ||
| Histone H2AX (H2a/x) (Histone H2A.X) | Nucleus | ||
| TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1) | Nucleus | ||
| Matrilin-2 | Secreted. | ||
| CDC42 small effector protein 1 (CDC42-binding protein SCIP1) (Small effector of CDC42 protein 1) | |||
| Ras-related protein Rab-34 (Ras-related protein Rab-39) (Ras-related protein Rah) | Cytoplasm | ||
| RING finger protein 10 | Cytoplasm | ||
| E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1) | autosomal dominant cerebellar ataxia autosomal recessive cerebellar ataxia | Cytoplasm | |
| Protein phosphatase 1A (EC 3.1.3.16) (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (Protein phosphatase IA) | Nucleus | ||
| ATP-dependent RNA helicase DHX30 (EC 3.6.4.13) (DEAH box protein 30) | Cytoplasm | ||
| T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed] | Cytoplasm | ||
| Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1) | Cytoplasm | ||
| COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1) | Cytoplasm, cytosol | ||
| Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) | Cytoplasm | ||
| Probable ergosterol biosynthetic protein 28 | Endoplasmic reticulum membrane | ||
| Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2) | |||
| Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha) | Nucleus | ||
| ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein) (NAD(P)HX dehydratase) | Mitochondrion | ||
| Thyroid hormone receptor alpha (Nuclear receptor subfamily 1 group A member 1) (V-erbA-related protein 7) (EAR-7) (c-erbA-1) (c-erbA-alpha) | Nucleus. | ||
| Histone deacetylase 2 (HD2) (EC 3.5.1.98) | Nucleus | ||
| Uncharacterized protein RAB5IF (Rab5-interacting protein) (RIP5) | |||
| Forkhead box protein J2 (Fork head homologous X) | Nucleus. | ||
| CST complex subunit STN1 (Oligonucleotide/oligosaccharide-binding fold-containing protein 1) (Suppressor of cdc thirteen homolog) | Nucleus | ||
| Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181) | Nucleus | ||
| Transforming acidic coiled-coil-containing protein 3 (ERIC-1) | Cytoplasm | ||
| Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) | Nucleus | ||
| Glycerate kinase (EC 2.7.1.31) (HBeAg-binding protein 4) | Isoform 1: Cytoplasm | ||
| Melanoma-associated antigen 10 (Cancer/testis antigen 1.10) (CT1.10) (MAGE-10 antigen) | Nucleus | ||
| 28S ribosomal protein S24, mitochondrial (MRP-S24) (S24mt) (Mitochondrial small ribosomal subunit protein uS3m) (bMRP-47) (bMRP47) | Mitochondrion | ||
| Retinoblastoma-associated protein (p105-Rb) (pRb) (Rb) (pp110) | Nucleus | ||
| Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6) | Parkinson disease | ||
| CREB-binding protein (EC 2.3.1.48) | |||
| WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1) | Cytoplasm | ||
| Cytoplasmic dynein 2 light intermediate chain 1 (Dynein 2 light intermediate chain) | Cytoplasm | ||
| Forkhead box protein P1 (Mac-1-regulated forkhead) (MFH) | autism spectrum disorder | Nucleus | |
| Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit) | |||
| ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5) | Isoform Beta: Nucleus, nucleoplasm | ||
| Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin-specific peptidase 50) | |||
| Forkhead box protein O1 (Forkhead box protein O1A) (Forkhead in rhabdomyosarcoma) | Cytoplasm | ||
| Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2) | Mitochondrion | ||
| Forkhead box protein K2 (Cellular transcription factor ILF-1) (FOXK1) (Interleukin enhancer-binding factor 1) | Nucleus | ||
| Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor) | Cell membrane | ||
| Probable tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase) (hOSGEP) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP) (tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP) | Cytoplasm | ||
| DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1) | |||
| TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa) | |||
| Zinc transporter ZIP4 (Solute carrier family 39 member 4) (Zrt- and Irt-like protein 4) (ZIP-4) | Cell membrane | ||
| Forkhead box protein N1 (Winged-helix transcription factor nude) | Nucleus. | ||
| Nuclear factor of activated T-cells, cytoplasmic 1 (NF-ATc1) (NFATc1) (NFAT transcription complex cytosolic component) (NF-ATc) (NFATc) | Cytoplasm | ||
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (EC 5.2.1.8) (Parvulin-14) (Par14) (hPar14) (Parvulin-17) (Par17) (hPar17) (Peptidyl-prolyl cis-trans isomerase Pin4) (PPIase Pin4) (Peptidyl-prolyl cis/trans isomerase EPVH) (hEPVH) (Rotamase Pin4) | |||
| Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) | Cell junction, desmosome | ||
| Putative ubiquitin-conjugating enzyme E2 D2-like protein (Ubiquitin carrier protein D2-like) (Ubiquitin-conjugating enzyme E2D N-terminal-like) (Ubiquitin-protein ligase D2-like) | |||
| Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued) | progressive muscular atrophy lateral sclerosis spinal muscular atrophy ... amyotrophic lateral sclerosis multiple system atrophy | Cytoplasm | |
| Phosphoglucomutase-1 (PGM 1) (EC 5.4.2.2) (Glucose phosphomutase 1) | Isoform 1: Cytoplasm. | ||
| Nebulin | Cytoplasm, myofibril, sarcomere | ||
| Spectrin beta chain, erythrocytic (Beta-I spectrin) | Cytoplasm, cytoskeleton | ||
| SNARE-associated protein Snapin (Biogenesis of lysosome-related organelles complex 1 subunit 7) (BLOC-1 subunit 7) (Synaptosomal-associated protein 25-binding protein) (SNAP-associated protein) | Membrane | ||
| Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain) | Cytoplasm | ||
| IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5) (p53 and DNA damage-regulated IQ motif protein) (PIQ) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (p58) | Cytoplasm | ||
| Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) | |||
| Intracellular hyaluronan-binding protein 4 (IHABP-4) (IHABP4) (Hyaluronan-binding protein 4) (Ki-1/57 intracellular antigen) | Nucleus | ||
| Annexin A11 (56 kDa autoantigen) (Annexin XI) (Annexin-11) (Calcyclin-associated annexin 50) (CAP-50) | lateral sclerosis amyotrophic lateral sclerosis | Cytoplasm | |
| WD repeat-containing protein 19 (Intraflagellar transport 144 homolog) | Cell projection, cilium | ||
| N-acetyltransferase 9 (EC 2.3.1.-) (Embryo brain-specific protein) | |||
| Snurportin-1 (RNA U transporter 1) | Nucleus | ||
| Hexokinase-1 (EC 2.7.1.1) (Brain form hexokinase) (Hexokinase type I) (HK I) | |||
| POC1 centriolar protein homolog A (Pix2) (Proteome of centriole protein 1A) (WD repeat-containing protein 51A) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2) | Nucleus | ||
| Ubiquitin-conjugating enzyme E2 C (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme C) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme C) (UbcH10) (Ubiquitin carrier protein C) (Ubiquitin-protein ligase C) | |||
| Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1) | Nucleus | ||
| Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A) (Autophagy-related ubiquitin-like modifier LC3 A) (MAP1 light chain 3-like protein 1) (MAP1A/MAP1B light chain 3 A) (MAP1A/MAP1B LC3 A) (Microtubule-associated protein 1 light chain 3 alpha) | Cytoplasm, cytoskeleton | ||
| Calcium-binding protein 39 (MO25alpha) (Protein Mo25) | Cytoplasm | ||
| Telomeric repeat-binding factor 1 (NIMA-interacting protein 2) (TTAGGG repeat-binding factor 1) (Telomeric protein Pin2/TRF1) | |||
| Emopamil-binding protein-like (Emopamil-binding-related protein) | Endoplasmic reticulum membrane | ||
| Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) | Cell membrane | ||
| Alpha-endosulfine (ARPP-19e) | Cytoplasm | ||
| mRNA-decapping enzyme 1A (EC 3.-.-.-) (Smad4-interacting transcriptional co-activator) (Transcription factor SMIF) | Cytoplasm, P-body | ||
| Microtubule-associated protein 4 (MAP-4) | Cytoplasm, cytoskeleton. | ||
| mRNA decay activator protein ZFP36 (G0/G1 switch regulatory protein 24) (Growth factor-inducible nuclear protein NUP475) (Tristetraprolin) (Zinc finger protein 36) (Zfp-36) | Nucleus | ||
| Tubulin alpha-4A chain (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain) | lateral sclerosis amyotrophic lateral sclerosis | Cytoplasm, cytoskeleton. | |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 1.6.99.3) (EC 7.1.1.2) (Complex I-20kD) (CI-20kD) (NADH-ubiquinone oxidoreductase 20 kDa subunit) (PSST subunit) | Parkinson disease | Mitochondrion | |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (Complex I-39kD) (CI-39kD) (NADH-ubiquinone oxidoreductase 39 kDa subunit) | Parkinson disease | Mitochondrion matrix | |
| 39S ribosomal protein L12, mitochondrial (L12mt) (MRP-L12) (5c5-2) (Mitochondrial large ribosomal subunit protein bL12m) | Mitochondrion | ||
| DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D) (RNA polymerase I 16 kDa subunit) (RPA16) (RPC16) (hRPA19) | Nucleus | ||
| Cytochrome c oxidase subunit 6C (Cytochrome c oxidase polypeptide VIc) | Mitochondrion inner membrane. | ||
| Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va) | Mitochondrion inner membrane. | ||
| Endothelin receptor type B (ET-B) (ET-BR) (Endothelin receptor non-selective type) | Cell membrane | ||
| Cytochrome c oxidase subunit 6B1 (Cytochrome c oxidase subunit VIb isoform 1) (COX VIb-1) | Mitochondrion intermembrane space | ||
| Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 1.10.2.2) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Rieske protein UQCRFS1) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 9 (Su9) (Subunit 9) (8 kDa subunit 9) (Complex III subunit IX) (Cytochrome b-c1 complex subunit 11) (Ubiquinol-cytochrome c reductase 8 kDa protein)] | Mitochondrion inner membrane | ||
| Zinc finger protein 414 | Nucleus | ||
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (Complex I-13kD-A) (CI-13kD-A) (NADH-ubiquinone oxidoreductase 13 kDa-A subunit) | Parkinson disease | Mitochondrion inner membrane | |
| Tetratricopeptide repeat protein 4 (TPR repeat protein 4) | |||
| Cysteine and histidine-rich domain-containing protein 1 (CHORD domain-containing protein 1) (CHORD-containing protein 1) (CHP-1) (Protein morgana) | |||
| Cytochrome c oxidase subunit 7A2, mitochondrial (Cytochrome c oxidase subunit VIIa-liver/heart) (Cytochrome c oxidase subunit VIIa-L) (Cytochrome c oxidase subunit VIIaL) | Mitochondrion inner membrane. | ||
| X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)) | Nucleus | ||
| Myosin-6 (Myosin heavy chain 6) (Myosin heavy chain, cardiac muscle alpha isoform) (MyHC-alpha) | |||
| Vacuolar protein sorting-associated protein 26A (Vesicle protein sorting 26A) (hVPS26) | Cytoplasm | ||
| Protein mab-21-like 2 | Nucleus | ||
| Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain) | Nucleus | ||
| NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC 1.6.99.3) (EC 7.1.1.2) (Complex I-51kD) (CI-51kD) (NADH dehydrogenase flavoprotein 1) (NADH-ubiquinone oxidoreductase 51 kDa subunit) | Parkinson disease | Mitochondrion inner membrane | |
| Homer protein homolog 1 (Homer-1) | Cytoplasm | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (CI-B14) (LYR motif-containing protein 6) (NADH-ubiquinone oxidoreductase B14 subunit) | Mitochondrion inner membrane | ||
| NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 1.6.99.3) (EC 7.1.1.2) (Complex I-75kD) (CI-75kD) | Parkinson disease | Mitochondrion inner membrane. | |
| NADH dehydrogenase [ubiquinone] 1 subunit C2 (Complex I-B14.5b) (CI-B14.5b) (Human lung cancer oncogene 1 protein) (HLC-1) (NADH-ubiquinone oxidoreductase subunit B14.5b) | Mitochondrion inner membrane | ||
| Mitochondrial intermembrane space import and assembly protein 40 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4) | Mitochondrion intermembrane space | ||
| Complement component 1 Q subcomponent-binding protein, mitochondrial (ASF/SF2-associated protein p32) (Glycoprotein gC1qBP) (C1qBP) (Hyaluronan-binding protein 1) (Mitochondrial matrix protein p32) (gC1q-R protein) (p33) (SF2AP32) | Mitochondrion matrix | ||
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (Complex I-18 kDa) (CI-18 kDa) (Complex I-AQDQ) (CI-AQDQ) (NADH-ubiquinone oxidoreductase 18 kDa subunit) | Parkinson disease | Mitochondrion inner membrane | |
| Cytochrome c oxidase subunit 6A1, mitochondrial (Cytochrome c oxidase polypeptide VIa-liver) (Cytochrome c oxidase subunit VIA-liver) (COX VIa-L) | Mitochondrion inner membrane. | ||
| Peroxisome biogenesis factor 10 (Peroxin-10) (Peroxisomal biogenesis factor 10) (Peroxisome assembly protein 10) (RING finger protein 69) | Peroxisome membrane | ||
| Cytochrome c oxidase subunit 2 (Cytochrome c oxidase polypeptide II) | Mitochondrion inner membrane | ||
| Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33) | Endoplasmic reticulum membrane | ||
| Zinc finger protein 503 | Nucleus | ||
| Granulins (Proepithelin) (PEPI) [Cleaved into: Acrogranin (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Progranulin); Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] | Secreted. | ||
| DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19) | Nucleus | ||
| Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 (EC 2.4.1.141) (EC 3.4.19.12) (Asparagine-linked glycosylation 13 homolog) (Glycosyltransferase 28 domain-containing protein 1) (UDP-N-acetylglucosamine transferase subunit ALG13 homolog) | Isoform 2: Endoplasmic reticulum | ||
| Complex I assembly factor TIMMDC1, mitochondrial (Protein M5-14) (Translocase of inner mitochondrial membrane domain-containing protein 1) (TIMM domain containing-protein 1) | Mitochondrion membrane | ||
| Cytochrome b-c1 complex subunit 7 (Complex III subunit 7) (Complex III subunit VII) (QP-C) (Ubiquinol-cytochrome c reductase complex 14 kDa protein) | Mitochondrion inner membrane. | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Complex I-42kD) (CI-42kD) (NADH-ubiquinone oxidoreductase 42 kDa subunit) | Parkinson disease | Mitochondrion matrix | |
| Synaptosomal-associated protein 29 (SNAP-29) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29) | Cytoplasm | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (Complex I-B14.5a) (CI-B14.5a) (NADH-ubiquinone oxidoreductase subunit B14.5a) | Mitochondrion inner membrane | ||
| B-cell lymphoma/leukemia 11B (BCL-11B) (B-cell CLL/lymphoma 11B) (COUP-TF-interacting protein 2) (Radiation-induced tumor suppressor gene 1 protein) (hRit1) | lateral sclerosis multiple sclerosis | Nucleus | |
| Transmembrane protein 132A (HSPA5-binding protein 1) | Golgi apparatus membrane | ||
| Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1) | Cell membrane | ||
| Zinc finger protein 524 | Nucleus | ||
| Delta-type opioid receptor (D-OR-1) (DOR-1) | Cell membrane | ||
| Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP) | Cell membrane | ||
| Zinc finger and BTB domain-containing protein 22 (Protein BING1) (Zinc finger and BTB domain-containing protein 22A) (Zinc finger protein 297) | Nucleus | ||
| Occludin | Cell membrane | ||
| Caveolin-1 | Golgi apparatus membrane | ||
| Nucleolar complex protein 4 homolog (NOC4 protein homolog) (NOC4-like protein) (Nucleolar complex-associated protein 4-like protein) | Nucleus membrane | ||
| Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain-interacting protein) (SSX2-interacting protein) | Cell junction, adherens junction | ||
| C2 calcium-dependent domain-containing protein 6 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein) | lateral sclerosis | ||
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (Complex I-ESSS) (CI-ESSS) (NADH-ubiquinone oxidoreductase ESSS subunit) (Neuronal protein 17.3) (Np17.3) (p17.3) | Parkinson disease | Mitochondrion inner membrane | |
| Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor alpha-induced protein 4) (TNF alpha-induced protein 4) [Cleaved into: Ephrin-A1, secreted form] | Cell membrane | ||
| Homeobox protein MOX-1 (Mesenchyme homeobox 1) | Nucleus | ||
| Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1) | Nucleus | ||
| Serum albumin | Secreted. | ||
| Deoxyribonuclease-2-beta (EC 3.1.22.1) (DNase II-like acid DNase) (DNase2-like acid DNase) (Deoxyribonuclease II beta) (DNase II beta) (Endonuclease DLAD) | Lysosome | ||
| N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Polypeptide GalNAc transferase 7) (GalNAc-T7) (pp-GaNTase 7) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) | Golgi apparatus membrane | ||
| Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (Protein 59) (Protein DMR-N9) | Perikaryon | ||
| Ras-related protein Rab-10 | Cytoplasmic vesicle membrane | ||
| CUGBP Elav-like family member 1 (CELF-1) (50 kDa nuclear polyadenylated RNA-binding protein) (Bruno-like protein 2) (CUG triplet repeat RNA-binding protein 1) (CUG-BP1) (CUG-BP- and ETR-3-like factor 1) (Deadenylation factor CUG-BP) (Embryo deadenylation element-binding protein homolog) (EDEN-BP homolog) (RNA-binding protein BRUNOL-2) | Nucleus | ||
| 40S ribosomal protein S27 (Metallopan-stimulin 1) (MPS-1) (Small ribosomal subunit protein eS27) | |||
| E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX) | Cytoplasm | ||
| Protein unc-93 homolog B1 (Unc-93B1) (hUNC93B1) | Endoplasmic reticulum membrane | ||
| Transcription factor IIIA (TFIIIA) | Nucleus. | ||
| Rap1 GTPase-GDP dissociation stimulator 1 (Exchange factor smgGDS) (SMG GDS protein) (SMG P21 stimulatory GDP/GTP exchange protein) | |||
| Protein unc-13 homolog B (Munc13-2) (munc13) | Cytoplasm | ||
| Ras-related protein Rab-32 | Mitochondrion | ||
| Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (GluA1) | Cell membrane | ||
| C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (FB22) (Fusin) (HM89) (LCR1) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (Lipopolysaccharide-associated protein 3) (LAP-3) (LPS-associated protein 3) (NPYRL) (Stromal cell-derived factor 1 receptor) (SDF-1 receptor) (CD antigen CD184) | Cell membrane | ||
| Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Protein-tyrosine phosphatase SHP-1) (SH-PTP1) | |||
| Sialomucin core protein 24 (MUC-24) (Endolyn) (Multi-glycosylated core protein 24) (MGC-24) (MGC-24v) (CD antigen CD164) | Lysosome membrane | ||
| Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35) | Nucleus | ||
| Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) | Cytoplasm | ||
| IQ domain-containing protein F1 | Cytoplasmic vesicle, secretory vesicle, acrosome | ||
| Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3) | Cytoplasm | ||
| Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK) | Cell junction, focal adhesion | ||
| Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b) | Cell membrane | ||
| Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3) | Cytoplasm | ||
| Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit) | |||
| Myb-related protein B (B-Myb) (Myb-like protein 2) | Nucleus. | ||
| Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2) | Endomembrane system | ||
| Cation-transporting ATPase 13A2 (EC 3.6.3.-) | Parkinson disease | Membrane | |
| Microtubule-associated protein RP/EB family member 3 (EB1 protein family member 3) (EBF3) (End-binding protein 3) (EB3) (RP3) | Cytoplasm, cytoskeleton | ||
| HLA class I histocompatibility antigen, B-7 alpha chain (MHC class I antigen B*7) | Membrane | ||
| Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK) | Endomembrane system | ||
| HLA class II histocompatibility antigen gamma chain (HLA-DR antigens-associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD antigen CD74) | Cell membrane | ||
| Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3) | Nucleus | ||
| Guanine nucleotide-binding protein subunit alpha-13 (G alpha-13) (G-protein subunit alpha-13) | Cell membrane | ||
| Palmitoyl-protein thioesterase 1 (PPT-1) (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1) | Lysosome | ||
| Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) | Cytoplasm, cytoskeleton | ||
| Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase) | Cytoplasm, cytosol | ||
| Cytochrome c | |||
| Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5) | Cytoplasm | ||
| Cytochrome P450 2E1 (EC 1.14.13.-) (4-nitrophenol 2-hydroxylase) (EC 1.14.13.n7) (CYPIIE1) (Cytochrome P450-J) | Endoplasmic reticulum membrane | ||
| (E3-independent) E2 ubiquitin-conjugating enzyme (EC 2.3.2.24) (E2/E3 hybrid ubiquitin-protein ligase UBE2O) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O) | Cytoplasm | ||
| P2X purinoceptor 4 (P2X4) (ATP receptor) (Purinergic receptor) | Membrane | ||
| Galectin-9C (Gal-9C) (Galectin-9-like protein B) | |||
| Cyclic AMP-responsive element-binding protein 3 (CREB-3) (cAMP-responsive element-binding protein 3) (Leucine zipper protein) (Luman) (Transcription factor LZIP-alpha) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3 (N-terminal Luman) (Transcriptionally active form)] | Isoform 1: Endoplasmic reticulum membrane | ||
| Protein C-ets-1 (p54) | Cytoplasm | ||
| L-lactate dehydrogenase A-like 6B (EC 1.1.1.27) | |||
| Cyclic AMP-responsive element-binding protein 3-like protein 1 (cAMP-responsive element-binding protein 3-like protein 1) (Old astrocyte specifically-induced substance) (OASIS) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 1] | Endoplasmic reticulum membrane | ||
| Transcription initiation factor IIA subunit 1 (General transcription factor IIA subunit 1) (TFIIAL) (Transcription initiation factor TFIIA 42 kDa subunit) (TFIIA-42) [Cleaved into: Transcription initiation factor IIA alpha chain (TFIIA p35 subunit); Transcription initiation factor IIA beta chain (TFIIA p19 subunit)] | Nucleus. | ||
| Calcyclin-binding protein (CacyBP) (hCacyBP) (S100A6-binding protein) (Siah-interacting protein) | Nucleus | ||
| Inositol 1,4,5-trisphosphate receptor-interacting protein (Protein DANGER) | Cell membrane | ||
| RNA polymerase II-associated protein 3 | |||
| Probable dimethyladenosine transferase (EC 2.1.1.183) (DIM1 dimethyladenosine transferase 1 homolog) (DIM1 dimethyladenosine transferase 1-like) (Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase) (Probable 18S rRNA dimethylase) (Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase) | Nucleus, nucleoplasm | ||
| Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) | Cytoplasm, cytoskeleton, spindle | ||
| Metaxin-1 (Mitochondrial outer membrane import complex protein 1) | Membrane | ||
| General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (Basic transcription factor 2 80 kDa subunit) (BTF2 p80) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (TFIIH basal transcription factor complex 80 kDa subunit) (TFIIH 80 kDa subunit) (TFIIH p80) (Xeroderma pigmentosum group D-complementing protein) | Nucleus | ||
| RNA cytidine acetyltransferase (EC 2.3.1.-) (18S rRNA cytosine acetyltransferase) (N-acetyltransferase 10) | Nucleus, nucleolus | ||
| Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase) | Cytoplasm | ||
| Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340) | |||
| WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein) | |||
| Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2) (Kelch-like protein 19) | |||
| Unconventional prefoldin RPB5 interactor 1 (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein) | Nucleus | ||
| Unconventional myosin-IXb (Unconventional myosin-9b) | Cytoplasm, cell cortex | ||
| Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.4.19.12) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) | |||
| Nephrocystin-4 (Nephroretinin) | Cytoplasm, cytoskeleton, cilium basal body | ||
| Protein 4.1 (P4.1) (4.1R) (Band 4.1) (EPB4.1) | Cytoplasm, cytoskeleton | ||
| Pantothenate kinase 2, mitochondrial (hPanK2) (EC 2.7.1.33) (Pantothenic acid kinase 2) | pantothenate kinase-associated neurodegeneration | Isoform 1: Mitochondrion. | |
| OTU domain-containing protein 5 (EC 3.4.19.12) (Deubiquitinating enzyme A) (DUBA) | |||
| Guanine nucleotide-binding protein subunit alpha-15 (G alpha-15) (G-protein subunit alpha-15) (Epididymis tissue protein Li 17E) (Guanine nucleotide-binding protein subunit alpha-16) (G alpha-16) (G-protein subunit alpha-16) | |||
| E3 ubiquitin-protein ligase SIAH1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH1) (Seven in absentia homolog 1) (Siah-1) (Siah-1a) | Parkinson disease | ||
| Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT) | autosomal recessive cerebellar ataxia | Endoplasmic reticulum | |
| Cystatin-S (Cystatin-4) (Cystatin-SA-III) (Salivary acidic protein 1) | Secreted | ||
| Follistatin (FS) (Activin-binding protein) | Secreted. | ||
| Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) | Membrane | ||
| Archaemetzincin-2 (EC 3.4.-.-) (Archeobacterial metalloproteinase-like protein 2) | |||
| Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK) | Mitochondrion. | ||
| Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) | |||
| POTE ankyrin domain family member I | |||
| F-box-like/WD repeat-containing protein TBL1X (SMAP55) (Transducin beta-like protein 1X) (Transducin-beta-like protein 1, X-linked) | Nucleus | ||
| Nephrocystin-1 (Juvenile nephronophthisis 1 protein) | autosomal recessive cerebellar ataxia primary cerebellar degeneration | Cell junction, adherens junction | |
| Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.4.19.12) (Deubiquitinating enzyme 49) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) | Nucleus | ||
| Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (51 kDa FK506-binding protein) (FKBP51) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed] | Cytoplasm, cytosol | ||
| Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) (Proto-oncogene c-Mos) | |||
| Protein BEX3 (Brain-expressed X-linked protein 3) (Nerve growth factor receptor-associated protein 1) (Ovarian granulosa cell 13.0 kDa protein HGR74) (p75NTR-associated cell death executor) | |||
| Centrosomal protein of 104 kDa (Cep104) | autosomal recessive cerebellar ataxia | Cell projection, cilium | |
| Ras-related C3 botulinum toxin substrate 3 (p21-Rac3) | |||
| Transcription factor E3 (Class E basic helix-loop-helix protein 33) (bHLHe33) | Nucleus. | ||
| E3 ubiquitin-protein ligase SIAH2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH2) (Seven in absentia homolog 2) (Siah-2) (hSiah2) | Cytoplasm | ||
| Eukaryotic translation initiation factor 6 (eIF-6) (B(2)GCN homolog) (B4 integrin interactor) (CAB) (p27(BBP)) | |||
| CCR4-NOT transcription complex subunit 8 (EC 3.1.13.4) (CAF1-like protein) (CALIFp) (CAF2) (CCR4-associated factor 8) (Caf1b) | Cytoplasm | ||
| Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 | Cell membrane | ||
| Proto-oncogene c-Fos (Cellular oncogene fos) (G0/G1 switch regulatory protein 7) | |||
| Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (G gamma-I) | Cell membrane | ||
| F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6) | |||
| Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | Cell membrane | ||
| 5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb) | |||
| Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13) | Cytoplasm | ||
| Nucleoside diphosphate kinase B (NDK B) (NDP kinase B) (EC 2.7.4.6) (C-myc purine-binding transcription factor PUF) (Histidine protein kinase NDKB) (EC 2.7.13.3) (nm23-H2) | Cytoplasm | ||
| CASP8 and FADD-like apoptosis regulator (Caspase homolog) (CASH) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (Cellular FLICE-like inhibitory protein) (c-FLIP) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Inhibitor of FLICE) (I-FLICE) (MACH-related inducer of toxicity) (MRIT) (Usurpin) [Cleaved into: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12] | lateral sclerosis | ||
| Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12) | Cell membrane | ||
| Neuroendocrine secretory protein 55 (NESP55) [Cleaved into: LHAL tetrapeptide; GPIPIRRH peptide] | Cytoplasmic vesicle, secretory vesicle | ||
| Kelch-like protein 38 | |||
| Homeobox protein Meis2 (Meis1-related protein 1) | Nucleus | ||
| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 (60 kDa BRG-1/Brm-associated factor subunit B) (BRG1-associated factor 60B) (BAF60B) | Nucleus | ||
| E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1) | |||
| S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (p19A) (Organ of Corti protein 2) (OCP-2) (Organ of Corti protein II) (OCP-II) (RNA polymerase II elongation factor-like protein) (SIII) (Transcription elongation factor B polypeptide 1-like) (p19skp1) | |||
| Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas) | Cell membrane | ||
| BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2) | |||
| Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin) | Cytoplasm | ||
| Ubl carboxyl-terminal hydrolase 18 (EC 3.4.19.-) (43 kDa ISG15-specific protease) (hUBP43) (ISG15-specific-processing protease) (Ubl thioesterase 18) | Isoform 1: Cytoplasm | ||
| Heat shock protein beta-8 (HspB8) (Alpha-crystallin C chain) (E2-induced gene 1 protein) (Protein kinase H11) (Small stress protein-like protein HSP22) | Cytoplasm | ||
| SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18) | |||
| Prenylated Rab acceptor protein 1 (PRA1 family protein 1) | Cell membrane | ||
| Acyl-CoA dehydrogenase family member 11 (ACAD-11) (EC 1.3.99.-) | Peroxisome | ||
| Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase) | Mitochondrion | ||
| Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3) | |||
| Proteasome subunit alpha type-1 (EC 3.4.25.1) (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain) | Cytoplasm | ||
| Peptidyl-tRNA hydrolase ICT1, mitochondrial (EC 3.1.1.29) (39S ribosomal protein L58, mitochondrial) (MRP-L58) (Digestion substraction 1) (DS-1) (Immature colon carcinoma transcript 1 protein) (Mitochondrial large ribosomal subunit protein mL62) | Mitochondrion | ||
| Membrane magnesium transporter 1 (ER membrane protein complex subunit 5) (Transmembrane protein 32) | Endoplasmic reticulum membrane | ||
| Upstream stimulatory factor 1 (Class B basic helix-loop-helix protein 11) (bHLHb11) (Major late transcription factor 1) | Nucleus. | ||
| Cytochrome c oxidase subunit 5B, mitochondrial (Cytochrome c oxidase polypeptide Vb) | Mitochondrion inner membrane. | ||
| Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1) | Cytoplasm, cytoskeleton | ||
| ATP-dependent zinc metalloprotease YME1L1 (EC 3.4.24.-) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin-associated metalloprotease) (PAMP) (YME1-like protein 1) | Mitochondrion inner membrane | ||
| Dynactin subunit 5 (Dynactin subunit p25) | Cytoplasm, cytoskeleton | ||
| ADP/ATP translocase 2 (ADP,ATP carrier protein 2) (ADP,ATP carrier protein, fibroblast isoform) (Adenine nucleotide translocator 2) (ANT 2) (Solute carrier family 25 member 5) [Cleaved into: ADP/ATP translocase 2, N-terminally processed] | Mitochondrion inner membrane | ||
| Cytochrome c oxidase subunit NDUFA4 (Complex I-MLRQ) (CI-MLRQ) (NADH-ubiquinone oxidoreductase MLRQ subunit) | Mitochondrion inner membrane | ||
| Protein bicaudal D homolog 2 (Bic-D 2) | spinal muscular atrophy | Golgi apparatus | |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (Complex I-15 kDa) (CI-15 kDa) (NADH-ubiquinone oxidoreductase 15 kDa subunit) | Mitochondrion inner membrane | ||
| Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) | Cytoplasm, cytoskeleton, cilium axoneme | ||
| Normal mucosa of esophagus-specific gene 1 protein (Protein FOAP-11) | Nucleus | ||
| Melanoma-associated antigen 11 (Cancer/testis antigen 1.11) (CT1.11) (MAGE-11 antigen) | Nucleus | ||
| Apolipoprotein E (Apo-E) | Alzheimer disease | Secreted | |
| Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) | Cell membrane | ||
| Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (CIG49) (ISG-60) (Interferon-induced 60 kDa protein) (IFI-60K) (Interferon-induced protein with tetratricopeptide repeats 4) (IFIT-4) (Retinoic acid-induced gene G protein) (P60) (RIG-G) | Cytoplasm | ||
| Protein lin-52 homolog | |||
| Ret finger protein-like 2 (RING finger protein 79) | |||
| DnaJ homolog subfamily B member 1 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40) (Human DnaJ protein 1) (hDj-1) | Cytoplasm | ||
| Bleomycin hydrolase (BH) (BLM hydrolase) (BMH) (EC 3.4.22.40) | Cytoplasm. | ||
| Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1) | Golgi apparatus, cis-Golgi network | ||
| Desmoglein-3 (130 kDa pemphigus vulgaris antigen) (PVA) (Cadherin family member 6) | Cell membrane | ||
| Zinc finger and BTB domain-containing protein 25 (Zinc finger protein 46) (Zinc finger protein KUP) | Nucleus. | ||
| Putative uncharacterized protein C17orf82 | |||
| DCC-interacting protein 13-beta (Dip13-beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2) | Early endosome membrane | ||
| Protein arginine N-methyltransferase 6 (EC 2.1.1.319) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6) (Histone-arginine N-methyltransferase PRMT6) | Nucleus | ||
| Lysine-specific histone demethylase 1A (EC 1.-.-.-) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) | Nucleus | ||
| WD repeat-containing protein 48 (USP1-associated factor 1) (WD repeat endosomal protein) (p80) | Nucleus | ||
| Pre-mRNA 3'-end-processing factor FIP1 (hFip1) (FIP1-like 1 protein) (Factor interacting with PAP) (Rearranged in hypereosinophilia) | Nucleus. | ||
| Golgi reassembly-stacking protein 2 (GRS2) (Golgi phosphoprotein 6) (GOLPH6) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59) | Golgi apparatus membrane | ||
| Maspardin (Acid cluster protein 33) (Spastic paraplegia 21 autosomal recessive Mast syndrome protein) (Spastic paraplegia 21 protein) | Cytoplasm, cytosol | ||
| Apoptosis regulator BAX (Bcl-2-like protein 4) (Bcl2-L-4) | Isoform Alpha: Mitochondrion outer membrane | ||
| Ras association domain-containing protein 3 | Cytoplasm | ||
| Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X) | Isoform Bcl-X(L): Mitochondrion inner membrane | ||
| Zinc finger CCCH domain-containing protein 4 | |||
| Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit) | |||
| Calsenilin (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3) | Cytoplasm | ||
| Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2) | autism spectrum disorder | Cell membrane | |
| Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57) | |||
| Transmembrane 4 L6 family member 18 | Membrane | ||
| C-terminal-binding protein 2 (CtBP2) | Nucleus | ||
| Pterin-4-alpha-carbinolamine dehydratase 2 (PHS 2) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase 2) (DcoH-like protein DCoHm) (Dimerization cofactor of hepatocyte nuclear factor 1 from muscle) (HNF-1-alpha dimerization cofactor) | |||
| RISC-loading complex subunit TARBP2 (TAR RNA-binding protein 2) (Trans-activation-responsive RNA-binding protein) | Cytoplasm | ||
| RWD domain-containing protein 2A | |||
| Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA) | Mitochondrion outer membrane | ||
| cAMP-responsive element modulator (Inducible cAMP early repressor) (ICER) | Nucleus. | ||
| C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) | Cytoplasm | ||
| A-kinase anchor protein 5 (AKAP-5) (A-kinase anchor protein 79 kDa) (AKAP 79) (H21) (cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein) | Membrane | ||
| Battenin (Batten disease protein) (Protein CLN3) | Lysosome membrane | ||
| Cyclic AMP-responsive element-binding protein 1 (CREB-1) (cAMP-responsive element-binding protein 1) | Nucleus | ||
| Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calmodulin-dependent calcineurin A subunit alpha isoform) | Cytoplasm | ||
| Presenilin-2 (PS-2) (EC 3.4.23.-) (AD3LP) (AD5) (E5-1) (STM-2) [Cleaved into: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit] | Alzheimer disease | Endoplasmic reticulum membrane | |
| Mothers against decapentaplegic homolog 9 (MAD homolog 9) (Mothers against DPP homolog 9) (Madh6) (SMAD family member 9) (SMAD 9) (Smad9) | Cytoplasm | ||
| GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53) | Cytoplasm | ||
| Glypican-1 [Cleaved into: Secreted glypican-1] | Pick disease Alzheimer disease | ||
| Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2) | Cytoplasm | ||
| Putative protein MSS51 homolog, mitochondrial (Zinc finger MYND domain-containing protein 17) | |||
| 26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27) | |||
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (Complex I-PDSW) (CI-PDSW) (NADH-ubiquinone oxidoreductase PDSW subunit) | Mitochondrion inner membrane | ||
| ER membrane protein complex subunit 6 (Transmembrane protein 93) | Membrane | ||
| ER membrane protein complex subunit 7 | Membrane | ||
| Decapping and exoribonuclease protein (DXO) (EC 3.1.13.-) (EC 3.6.1.-) (Dom-3 homolog Z) | Nucleus | ||
| Tectonic-2 | Membrane | ||
| LIM domain only protein 3 (LMO-3) (Neuronal-specific transcription factor DAT1) (Rhombotin-3) | |||
| Sodium channel modifier 1 | Nucleus, nucleoplasm | ||
| Tectonic-3 | Membrane | ||
| Transmembrane protein 237 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein) | lateral sclerosis | Membrane | |
| Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein) | multiple system atrophy | Cytoplasm | |
| ER membrane protein complex subunit 3 (Transmembrane protein 111) | Membrane | ||
| Emerin | Nucleus inner membrane | ||
| Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I) | |||
| Zinc finger protein 250 (Zinc finger protein 647) | Nucleus | ||
| SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2) | Nucleus. | ||
| B melanoma antigen 4 (Cancer/testis antigen 2.4) (CT2.4) | Secreted | ||
| Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 3.6.3.49) (cAMP-dependent chloride channel) | Apical cell membrane | ||
| RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca) | Cytoplasm | ||
| Lamin-B1 | multiple sclerosis | Nucleus inner membrane | |
| DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21) | Nucleus | ||
| Protein FAM90A1 | |||
| Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1) | Nucleus | ||
| U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5) | Nucleus | ||
| Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) | Late endosome | ||
| Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks) | |||
| Deleted in azoospermia protein 2 | Cytoplasm | ||
| EF-hand domain-containing family member C2 | |||
| AP-5 complex subunit mu-1 (Adaptor-related protein complex 5 subunit mu-1) (Mu5) (Mu-2-related death-inducing protein) (MuD) (Putative HIV-1 infection-related protein) | Cytoplasm, cytosol | ||
| Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin] | Cytoplasm | ||
| Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor (Urogastrone)] | Membrane | ||
| Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) | autosomal recessive cerebellar ataxia | Nucleus outer membrane | |
| Heat shock 70 kDa protein 1B (Heat shock 70 kDa protein 2) (HSP70-2) (HSP70.2) | Cytoplasm | ||
| U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD) | Nucleus | ||
| Protein argonaute-4 (Argonaute4) (hAgo4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4) | Cytoplasm, P-body | ||
| Hippocalcin-like protein 4 (HLP4) | |||
| Cadherin-13 (Heart cadherin) (H-cadherin) (P105) (Truncated cadherin) (T-cad) (T-cadherin) | Alzheimer disease lateral sclerosis multiple sclerosis | Cell membrane | |
| 14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed] | Cytoplasm | ||
| Neurocalcin-delta | |||
| DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460) | Nucleus | ||
| Visinin-like protein 1 (VILIP) (VLP-1) (Hippocalcin-like protein 3) (HLP3) | |||
| Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) | Nucleus | ||
| Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17) | Cytoplasm, cytoskeleton | ||
| F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1) | Nucleus | ||
| Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer) | Cytoplasm, P-body | ||
| Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain) | Cytoplasm, cytoskeleton. | ||
| Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56) | Isoform 1: Cell membrane | ||
| Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28) | Nucleus | ||
| Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) | olivopontocerebellar atrophy | Cell membrane | |
| Ras-related protein Rab-3A | Cell membrane | ||
| Suppressor of IKBKE 1 (Suppressor of IKK-epsilon) | Cytoplasm | ||
| Syntaxin-1B (Syntaxin-1B1) (Syntaxin-1B2) | Isoform 1: Membrane | ||
| Calretinin (CR) (29 kDa calbindin) | |||
| SUN domain-containing protein 2 (Protein unc-84 homolog B) (Rab5-interacting protein) (Rab5IP) (Sad1/unc-84 protein-like 2) | Nucleus inner membrane | ||
| LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1) | |||
| Ral GTPase-activating protein subunit beta (p170) | |||
| Tubulin alpha-1C chain (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain] | Cytoplasm, cytoskeleton. | ||
| SWI/SNF complex subunit SMARCC1 (BRG1-associated factor 155) (BAF155) (SWI/SNF complex 155 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1) | Nucleus | ||
| ATP-dependent RNA helicase DDX42 (EC 3.6.4.13) (DEAD box protein 42) (RNA helicase-like protein) (RHELP) (RNA helicase-related protein) (RNAHP) (SF3b DEAD box protein) (Splicing factor 3B-associated 125 kDa protein) (SF3b125) | |||
| Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin) | |||
| Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3) | Cytoplasm | ||
| Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4) | Cytoplasm | ||
| Nesprin-2 (KASH domain-containing protein 2) (KASH2) (Nuclear envelope spectrin repeat protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE) (Synaptic nuclear envelope protein 2) (Syne-2) | Nucleus outer membrane | ||
| Probable E3 ubiquitin-protein ligase HERC3 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 3) (HECT-type E3 ubiquitin transferase HERC3) | |||
| Endophilin-A1 (EEN-B1) (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2) | Cytoplasm | ||
| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (BRG1-associated factor 47) (BAF47) (Integrase interactor 1 protein) (SNF5 homolog) (hSNF5) | Nucleus. | ||
| Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III) | Cytoplasm, cytoskeleton. | ||
| Histone deacetylase complex subunit SAP130 (130 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p130) | Nucleus | ||
| Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit) | |||
| Zinc finger Ran-binding domain-containing protein 2 (Zinc finger protein 265) (Zinc finger, splicing) | Nucleus | ||
| Fanconi anemia group I protein (Protein FACI) | Nucleus | ||
| Fetal and adult testis-expressed transcript protein (Cancer/testis antigen 43) (CT43) (Tumor antigen BJ-HCC-2) | Mitochondrion | ||
| Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7) | |||
| Tripartite motif-containing protein 42 | |||
| Proto-oncogene vav | |||
| Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (hGAA1) | autosomal recessive cerebellar ataxia | Endoplasmic reticulum membrane | |
| Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed] | Cytoplasm | ||
| Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (2HOR0202) (Cell growth-inhibiting gene 38 protein) (Sin3-associated polypeptide p18) | Nucleus | ||
| Activator of basal transcription 1 (hABT1) (Basal transcriptional activator) | Nucleus | ||
| Spliceosome RNA helicase DDX39B (EC 3.6.4.13) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (DEAD box protein UAP56) (HLA-B-associated transcript 1 protein) | |||
| Developmental pluripotency-associated protein 4 | Nucleus | ||
| PHD finger protein 7 (Testis development protein NYD-SP6) | Nucleus | ||
| Polycomb protein SUZ12 (Chromatin precipitated E2F target 9 protein) (ChET 9 protein) (Joined to JAZF1 protein) (Suppressor of zeste 12 protein homolog) | Nucleus | ||
| Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 1) (HSP70-1) (HSP70.1) | Cytoplasm | ||
| Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 3) (NLI-IF) (NLI-interacting factor 3) (Small C-terminal domain phosphatase 1) (SCP1) (Small CTD phosphatase 1) | Nucleus | ||
| Dual specificity phosphatase DUPD1 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase 27) | Cytoplasm | ||
| Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1) | Cytoplasm | ||
| Lupus La protein (La autoantigen) (La ribonucleoprotein) (Sjoegren syndrome type B antigen) (SS-B) | Nucleus | ||
| Inositol-3-phosphate synthase 1 (IPS 1) (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase) (MI-1-P synthase) (MIP synthase) (hIPS) (Myo-inositol 1-phosphate synthase A1) (hINO1) | Cytoplasm | ||
| Germ cell-less protein-like 1 | Nucleus matrix | ||
| Solute carrier family 52, riboflavin transporter, member 1 (Porcine endogenous retrovirus A receptor 2) (PERV-A receptor 2) (Protein GPR172B) (Riboflavin transporter 1) (hRFT1) | Cell membrane | ||
| Tubulin beta chain (Tubulin beta-5 chain) | Cytoplasm, cytoskeleton | ||
| Tubulin beta-2A chain (Tubulin beta class IIa) | Cytoplasm, cytoskeleton | ||
| E3 ubiquitin-protein ligase TRIM69 (EC 2.3.2.27) (RFP-like domain-containing protein trimless) (RING finger protein 36) (RING-type E3 ubiquitin transferase TRIM69) (Tripartite motif-containing protein 69) | Cytoplasm | ||
| Barrier-to-autointegration factor (Breakpoint cluster region protein 1) [Cleaved into: Barrier-to-autointegration factor, N-terminally processed] | Barrier-to-autointegration factor: Nucleus | ||
| Tubulin alpha-1A chain (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain] | Cytoplasm, cytoskeleton. | ||
| EH domain-binding protein 1-like protein 1 | Endosome | ||
| Wilms tumor protein 1-interacting protein (WT1-interacting protein) | Cell junction, adherens junction | ||
| LIM domain-containing protein ajuba | |||
| Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2) | Cytoplasm | ||
| Gamma-tubulin complex component 2 (GCP-2) (hGCP2) (Gamma-ring complex protein 103 kDa) (h103p) (hGrip103) (Spindle pole body protein Spc97 homolog) (hSpc97) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Bystin | Cytoplasm | ||
| Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1) | Cytoplasm, cytosol | ||
| Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.4.19.12) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) | |||
| GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein) | Parkinson disease | ||
| Neuropathy target esterase (EC 3.1.1.5) (Patatin-like phospholipase domain-containing protein 6) | spastic ataxia | Endoplasmic reticulum membrane | |
| WW domain-binding protein 1 (WBP-1) | |||
| Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha) | |||
| Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) | Cytoplasm | ||
| Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117) | Isoform 1: Cell membrane | ||
| Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck) | |||
| Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn) | Cell membrane | ||
| Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Calsenilin-like protein) (Potassium channel-interacting protein 4) | Cell membrane | ||
| Platelet-derived growth factor receptor-like protein (PDGFR-like protein) (PDGF receptor beta-like tumor suppressor) | Secreted | ||
| Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1) | |||
| Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1) | Cytoplasm | ||
| Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk) | Cell membrane | ||
| Transcription factor PU.1 (31 kDa-transforming protein) | Nucleus | ||
| Vacuolar protein sorting-associated protein 52 homolog (SAC2 suppressor of actin mutations 2-like protein) | Golgi apparatus, trans-Golgi network membrane | ||
| Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1) | Isoform 2: Nucleus. | ||
| Protein FAM186B | |||
| WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box-containing WD protein SWiP-1) | |||
| Tripartite motif-containing protein 10 (B30-RING finger protein) (RING finger protein 9) | Cytoplasm | ||
| Protein FAM210B, mitochondrial | Mitochondrion | ||
| Procollagen galactosyltransferase 2 (EC 2.4.1.50) (Collagen beta(1-O)galactosyltransferase 2) (ColGalT 2) (Glycosyltransferase 25 family member 2) (Hydroxylysine galactosyltransferase 2) | Endoplasmic reticulum lumen | ||
| Transmembrane 4 L6 family member 20 | autism spectrum disorder | Membrane | |
| Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta) | Cytoplasm | ||
| Delta-sarcoglycan (Delta-SG) (35 kDa dystrophin-associated glycoprotein) (35DAG) | Cell membrane, sarcolemma | ||
| Caseinolytic peptidase B protein homolog (EC 3.6.1.3) (Suppressor of potassium transport defect 3) | Mitochondrion | ||
| Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (Fp) | Mitochondrion inner membrane | ||
| Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B-Val; Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)] | Lysosome | ||
| Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) | Cytoplasm | ||
| Coagulation factor XI (FXI) (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) [Cleaved into: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain] | Secreted. | ||
| Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain] | Secreted. | ||
| X-linked retinitis pigmentosa GTPase regulator | Cytoplasm, cytoskeleton, flagellum axoneme | ||
| Antithrombin-III (ATIII) (Serpin C1) | Secreted, extracellular space. | ||
| mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41) | Cytoplasm | ||
| Caspase-6 (CASP-6) (EC 3.4.22.59) (Apoptotic protease Mch-2) [Cleaved into: Caspase-6 subunit p18; Caspase-6 subunit p11] | Cytoplasm. | ||
| F-box/LRR-repeat protein 18 (F-box and leucine-rich repeat protein 18) | |||
| Protein FAM45A | |||
| RNA-binding protein 4 (Lark homolog) (hLark) (RNA-binding motif protein 4) (RNA-binding motif protein 4a) | |||
| E3 ubiquitin-protein ligase RNF168 (hRNF168) (EC 2.3.2.27) (RING finger protein 168) (RING-type E3 ubiquitin transferase RNF168) | Nucleus | ||
| Membrane-spanning 4-domains subfamily A member 4A (CD20 antigen-like 1) (Four-span transmembrane protein 1) | Membrane | ||
| Elongation factor 1-alpha 2 (EF-1-alpha-2) (Eukaryotic elongation factor 1 A-2) (eEF1A-2) (Statin-S1) | Nucleus | ||
| 60S acidic ribosomal protein P2 (Large ribosomal subunit protein P2) (Renal carcinoma antigen NY-REN-44) | |||
| Syntaxin-5 | Endoplasmic reticulum-Golgi intermediate compartment membrane | ||
| E3 ubiquitin-protein ligase RBX1 (EC 2.3.2.27) (EC 2.3.2.32) (E3 ubiquitin-protein transferase RBX1) (Protein ZYP) (RING finger protein 75) (RING-box protein 1) (Rbx1) (Regulator of cullins 1) (ROC1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed (E3 ubiquitin-protein transferase RBX1, N-terminally processed)] | Cytoplasm | ||
| Phytanoyl-CoA hydroxylase-interacting protein (Phytanoyl-CoA hydroxylase-associated protein 1) (PAHX-AP1) (PAHXAP1) | |||
| Macrophage migration inhibitory factor (MIF) (EC 5.3.2.1) (Glycosylation-inhibiting factor) (GIF) (L-dopachrome isomerase) (L-dopachrome tautomerase) (EC 5.3.3.12) (Phenylpyruvate tautomerase) | Secreted | ||
| Transmembrane protein 42 | Membrane | ||
| Elongation factor 2 (EF-2) | Cytoplasm | ||
| Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (Rubicon) (Beclin-1 associated RUN domain containing protein) (Baron) | autosomal recessive cerebellar ataxia | Late endosome | |
| Actin-related protein 5 (hARP5) (Sarcoma antigen NY-SAR-16) | Nucleus | ||
| Polyamine-modulated factor 1 (PMF-1) | Nucleus | ||
| WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2) | Preautophagosomal structure membrane | ||
| DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe) | |||
| Growth arrest and DNA damage-inducible proteins-interacting protein 1 (39S ribosomal protein L59, mitochondrial) (MRP-L59) (CKII beta-associating protein) (CR6-interacting factor 1) (CRIF1) (Mitochondrial large ribosomal subunit protein mL64) (Papillomavirus L2-interacting nuclear protein 1) (PLINP) (PLINP-1) (p53-responsive gene 6 protein) | Mitochondrion | ||
| 60S ribosomal protein L38 (Large ribosomal subunit protein eL38) | |||
| 40S ribosomal protein S29 (Small ribosomal subunit protein uS14) | Cytoplasm, cytosol | ||
| Heterogeneous nuclear ribonucleoprotein D-like (hnRNP D-like) (hnRNP DL) (AU-rich element RNA-binding factor) (JKT41-binding protein) (Protein laAUF1) | Nucleus | ||
| Zinc finger matrin-type protein 2 | Nucleus | ||
| tRNA-splicing endonuclease subunit Sen15 (SEN15 homolog) (HsSEN15) (tRNA-intron endonuclease Sen15) | pontocerebellar hypoplasia | Nucleus | |
| Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) | Alzheimer disease | Membrane | |
| Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog) | X-linked hereditary ataxia autism spectrum disorder autosomal dominant cerebellar ataxia | Cytoplasm | |
| Selenocysteine lyase (hSCL) (EC 4.4.1.16) | Cytoplasm, cytosol | ||
| Peroxiredoxin-1 (EC 1.11.1.15) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) | Alzheimer disease | Cytoplasm | |
| Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68) | Nucleus, nucleolus | ||
| Nucleolysin TIAR (TIA-1-related protein) | Cytoplasm | ||
| Tumor protein 63 (p63) (Chronic ulcerative stomatitis protein) (CUSP) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) (p40) (p51) | Nucleus | ||
| Transmembrane protein 144 | Membrane | ||
| Protein FAM104A | |||
| Coiled-coil domain-containing protein 57 | |||
| DNA polymerase delta catalytic subunit (EC 2.7.7.7) (EC 3.1.11.-) (DNA polymerase subunit delta p125) | Nucleus | ||
| 60S ribosomal protein L8 (Large ribosomal subunit protein uL2) | Cytoplasm | ||
| Fibrinogen gamma chain | Secreted | ||
| Ferrochelatase, mitochondrial (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase) | Mitochondrion inner membrane | ||
| Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) (Viral integration site protein INT-6 homolog) (eIF-3 p48) | Cytoplasm | ||
| Receptor expression-enhancing protein 6 (Polyposis locus protein 1-like 1) | Endoplasmic reticulum membrane | ||
| Protein Hook homolog 1 (h-hook1) (hHK1) | Cytoplasm | ||
| Endothelin-1 (Preproendothelin-1) (PPET1) [Cleaved into: Endothelin-1 (ET-1); Big endothelin-1] | Parkinson disease | Secreted. | |
| Protein FAM124B | Nucleus | ||
| 60S ribosomal protein L6 (Large ribosomal subunit protein eL6) (Neoplasm-related protein C140) (Tax-responsive enhancer element-binding protein 107) (TaxREB107) | Cytoplasm, cytosol | ||
| Baculoviral IAP repeat-containing protein 7 (EC 2.3.2.27) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) (RING-type E3 ubiquitin transferase BIRC7) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)] | Nucleus | ||
| Ubiquitin-40S ribosomal protein S27a (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; 40S ribosomal protein S27a (Small ribosomal subunit protein eS31)] | Ubiquitin: Cytoplasm | ||
| Protein FAM170A (Zinc finger domain-containing protein) (Zinc finger protein ZNFD) | Nucleus | ||
| 40S ribosomal protein S15a (Small ribosomal subunit protein uS8) | |||
| La-related protein 4 (La ribonucleoprotein domain family member 4) | Cytoplasm, Stress granule | ||
| Heat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom) | |||
| Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein) | Endoplasmic reticulum lumen | ||
| Armadillo repeat-containing X-linked protein 3 (ARM protein lost in epithelial cancers on chromosome X 3) (Protein ALEX3) | Mitochondrion outer membrane | ||
| H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7) | Lysosome membrane | ||
| Uncharacterized protein C4orf17 | |||
| Teratocarcinoma-derived growth factor 1 (Cripto-1 growth factor) (CRGF) (Epidermal growth factor-like cripto protein CR1) | Cell membrane | ||
| G-patch domain and KOW motifs-containing protein (G-patch domain-containing protein 5) (Protein MOS2 homolog) (Protein T54) | Nucleus | ||
| 60S ribosomal protein L4 (60S ribosomal protein L1) (Large ribosomal subunit protein uL4) | |||
| Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1) | Nucleus, nucleoplasm | ||
| Protein FAM187B (Transmembrane protein 162) | Membrane | ||
| ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (Helicase-like protein 2) (HLP2) | |||
| U1 small nuclear ribonucleoprotein C (U1 snRNP C) (U1-C) (U1C) | Nucleus | ||
| 60S ribosomal protein L23 (60S ribosomal protein L17) (Large ribosomal subunit protein uL14) | |||
| Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed] | autism spectrum disorder | Nucleus, nucleoplasm. | |
| Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] | Cytoplasm. | ||
| 60S ribosomal protein L24 (60S ribosomal protein L30) (Large ribosomal subunit protein eL24) | |||
| Kininogen-1 (Alpha-2-thiol proteinase inhibitor) (Fitzgerald factor) (High molecular weight kininogen) (HMWK) (Williams-Fitzgerald-Flaujeac factor) [Cleaved into: Kininogen-1 heavy chain; T-kinin (Ile-Ser-Bradykinin); Bradykinin (Kallidin I); Lysyl-bradykinin (Kallidin II); Kininogen-1 light chain; Low molecular weight growth-promoting factor] | Secreted, extracellular space. | ||
| 40S ribosomal protein S20 (Small ribosomal subunit protein uS10) | Cytoplasm | ||
| Rhomboid domain-containing protein 3 | Membrane | ||
| 60S ribosomal protein L11 (CLL-associated antigen KW-12) (Large ribosomal subunit protein uL5) | Nucleus, nucleolus | ||
| 60S ribosomal protein L31 (Large ribosomal subunit protein eL31) | |||
| Rhomboid-related protein 4 (RRP4) (EC 3.4.21.105) (Rhomboid domain-containing protein 1) (Rhomboid-like protein 4) | Membrane | ||
| Calpain-15 (EC 3.4.22.-) (Small optic lobes homolog) | |||
| Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1) | Nucleus | ||
| CDK-activating kinase assembly factor MAT1 (CDK7/cyclin-H assembly factor) (Cyclin-G1-interacting protein) (Menage a trois) (RING finger protein 66) (RING finger protein MAT1) (p35) (p36) | Nucleus. | ||
| Kelch-like protein 15 | Nucleus | ||
| COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15) | Cytoplasm | ||
| Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5) | Nucleus | ||
| Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) | Nucleus | ||
| Heterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed] | Nucleus, nucleoplasm. | ||
| Calcium-binding protein 8 (CaBP8) (Calneuron I) (Calneuron-1) | Golgi apparatus, trans-Golgi network membrane | ||
| DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog) | |||
| Protein FAM221A | |||
| Protein FAM222B | |||
| Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Tumor rejection antigen 1) (gp96 homolog) | |||
| Integral membrane protein 2B (Immature BRI2) (imBRI2) (Protein E25B) (Transmembrane protein BRI) (Bri) [Cleaved into: BRI2, membrane form (Mature BRI2) (mBRI2); BRI2 intracellular domain (BRI2 ICD); BRI2C, soluble form; Bri23 peptide (Bri2-23) (ABri23) (C-terminal peptide) (P23 peptide)] | spastic ataxia autosomal dominant cerebellar ataxia | Integral membrane protein 2B: Golgi apparatus membrane | |
| 40S ribosomal protein S14 (Small ribosomal subunit protein uS11) | |||
| EP300-interacting inhibitor of differentiation 2B (EID-2B) (EID-2-like inhibitor of differentiation 3) (EID-3) | Nucleus | ||
| Melanoma-associated antigen E1 (Alpha-dystrobrevin-associated MAGE Protein) (DAMAGE) (Hepatocellular carcinoma-associated protein 1) (MAGE-E1 antigen) | autism spectrum disorder | Cytoplasm, perinuclear region | |
| DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA) | Nucleus | ||
| Caspase-8 (CASP-8) (EC 3.4.22.61) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) (FADD-homologous ICE/ced-3-like protease) (FADD-like ICE) (FLICE) (ICE-like apoptotic protease 5) (MORT1-associated ced-3 homolog) (MACH) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10] | lateral sclerosis multiple sclerosis | Cytoplasm. | |
| Keratin, type II cytoskeletal 75 (Cytokeratin-75) (CK-75) (Keratin-6 hair follicle) (hK6hf) (Keratin-75) (K75) (Type II keratin-K6hf) (Type-II keratin Kb18) | |||
| Nuclear pore complex protein Nup133 (133 kDa nucleoporin) (Nucleoporin Nup133) | Nucleus, nuclear pore complex | ||
| Forkhead box protein I1 (Forkhead-related protein FKHL10) (Forkhead-related transcription factor 6) (FREAC-6) (Hepatocyte nuclear factor 3 forkhead homolog 3) (HFH-3) (HNF-3/fork-head homolog 3) | Nucleus. | ||
| Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-) | Cytoplasm, cytosol | ||
| F-box only protein 17 (F-box only protein 26) | |||
| Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.4.19.12) (Deubiquitinating enzyme 21) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) | Cytoplasm | ||
| E3 ubiquitin-protein ligase Praja-1 (Praja1) (EC 2.3.2.27) (RING finger protein 70) (RING-type E3 ubiquitin transferase Praja-1) | |||
| 40S ribosomal protein S4, X isoform (SCR10) (Single copy abundant mRNA protein) (Small ribosomal subunit protein eS4) | Cytoplasm | ||
| Survival motor neuron protein (Component of gems 1) (Gemin-1) | spinal muscular atrophy | Nucleus, gem | |
| Solute carrier family 2, facilitated glucose transporter member 1 (Glucose transporter type 1, erythrocyte/brain) (GLUT-1) (HepG2 glucose transporter) | episodic ataxia spastic ataxia | ||
| Platelet-activating factor acetylhydrolase IB subunit gamma (EC 3.1.1.47) (PAF acetylhydrolase 29 kDa subunit) (PAF-AH 29 kDa subunit) (PAF-AH subunit gamma) (PAFAH subunit gamma) | Cytoplasm. | ||
| V-type proton ATPase subunit H (V-ATPase subunit H) (Nef-binding protein 1) (NBP1) (Protein VMA13 homolog) (V-ATPase 50/57 kDa subunits) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD) | |||
| Enhancer of rudimentary homolog | |||
| Protein eva-1 homolog B (Protein FAM176B) | Membrane | ||
| DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB) | Nucleus | ||
| Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit) | Nucleus, nucleoplasm. | ||
| Zinc finger protein 41 homolog (Zfp-41) | Nucleus | ||
| Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein) | Nucleus | ||
| Sperm acrosome membrane-associated protein 4 (Sperm acrosomal membrane-associated protein 14) | Cell membrane | ||
| Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG) | Cytoplasm, cytosol | ||
| Polyubiquitin-B [Cleaved into: Ubiquitin] | Ubiquitin: Cytoplasm | ||
| RNA-binding protein 24 (RNA-binding motif protein 24) (RNA-binding region-containing protein 6) | Nucleus | ||
| Glycodelin (GD) (Placental protein 14) (PP14) (Pregnancy-associated endometrial alpha-2 globulin) (PAEG) (PEG) (Progestagen-associated endometrial protein) (Progesterone-associated endometrial protein) (Zona-binding inhibitory factor-1) (ZIF-1) | Secreted | ||
| Ubiquitin-like protein FUBI | |||
| TATA-binding protein-associated factor 2N (68 kDa TATA-binding protein-associated factor) (TAF(II)68) (TAFII68) (RNA-binding protein 56) | Nucleus | ||
| Zinc finger and SCAN domain-containing protein 20 (Zinc finger protein 31) (Zinc finger protein 360) (Zinc finger protein KOX29) | Nucleus | ||
| Sorting nexin-4 | Early endosome | ||
| Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (Sm-D autoantigen) (snRNP core protein D1) | Cytoplasm, cytosol | ||
| FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-) | Parkinson disease | Mitochondrion inner membrane | |
| 14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin) | Cytoplasm | ||
| Calcium and integrin-binding protein 1 (CIB) (Calcium- and integrin-binding protein) (CIBP) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP) (SNK-interacting protein 2-28) (SIP2-28) | |||
| DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23) | |||
| Chondroitin sulfate synthase 2 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 2) (Chondroitin-polymerizing factor) (ChPF) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (N-acetylgalactosaminyltransferase 2) | Isoform 1: Golgi apparatus, Golgi stack membrane | ||
| Phosphatidylcholine-sterol acyltransferase (EC 2.3.1.43) (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase) | Secreted | ||
| Retinol-binding protein 3 (Interphotoreceptor retinoid-binding protein) (IRBP) (Interstitial retinol-binding protein) | |||
| Interferon regulatory factor 5 (IRF-5) | |||
| F-box only protein 7 | Parkinson disease | ||
| Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like protein mcs94-1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein F, N-terminally processed] | Nucleus, nucleoplasm. | ||
| Stabilizer of axonemal microtubules 1 | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole | ||
| Late cornified envelope protein 2B (Late envelope protein 10) (Skin-specific protein Xp5) (Small proline-rich-like epidermal differentiation complex protein 1B) | |||
| Rab-3A-interacting protein (Rab3A-interacting protein) (Rabin-3) (SSX2-interacting protein) | |||
| Kelch-like protein 8 | |||
| cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI) | Cytoplasm | ||
| Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat-containing gene 10 protein) | Nucleus | ||
| Metaxin-2 (Mitochondrial outer membrane import complex protein 2) | Mitochondrion outer membrane | ||
| BTB/POZ domain-containing protein KCTD7 | Cell membrane | ||
| TBC1 domain family member 23 (HCV non-structural protein 4A-transactivated protein 1) | pontocerebellar hypoplasia | Golgi apparatus, trans-Golgi network | |
| Heme oxygenase 2 (HO-2) (EC 1.14.14.18) | Microsome | ||
| Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) | Cytoplasm | ||
| Protein S100-A10 (Calpactin I light chain) (Calpactin-1 light chain) (Cellular ligand of annexin II) (S100 calcium-binding protein A10) (p10 protein) (p11) | |||
| Melanoma antigen preferentially expressed in tumors (Opa-interacting protein 4) (OIP-4) (Preferentially expressed antigen of melanoma) | Nucleus | ||
| Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (APOBEC1-binding protein 1) (ABBP-1) | Nucleus | ||
| BRISC and BRCA1-A complex member 1 (Mediator of RAP80 interactions and targeting subunit of 40 kDa) (New component of the BRCA1-A complex) | Cytoplasm | ||
| RNA-binding protein 14 (Paraspeckle protein 2) (PSP2) (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein) | Nucleus | ||
| Bifunctional purine biosynthesis protein PURH [Cleaved into: Bifunctional purine biosynthesis protein PURH, N-terminally processed] [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)] | |||
| NEDD8-conjugating enzyme Ubc12 (EC 2.3.2.-) (NEDD8 carrier protein) (Ubiquitin-conjugating enzyme E2 M) | |||
| 60S ribosomal protein L18 (Large ribosomal subunit protein eL18) | Cytoplasm, cytosol | ||
| Nucleolin (Protein C23) | |||
| Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) | Secreted | ||
| Fibulin-2 (FIBL-2) | Secreted, extracellular space, extracellular matrix. | ||
| Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase) | Mitochondrion inner membrane. | ||
| Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1) | Isoform Alpha: Cytoplasm | ||
| Vimentin | Cytoplasm | ||
| Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein) | |||
| Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (CMH-1) (ICE-like apoptotic protease 3) (ICE-LAP3) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11] | Cytoplasm. | ||
| BTB/POZ domain-containing protein KCTD3 (Renal carcinoma antigen NY-REN-45) | Cell membrane | ||
| Kelch-like protein 42 (Cullin-3-binding protein 9) (Ctb9) (Kelch domain-containing protein 5) | Cytoplasm | ||
| Annexin A7 (Annexin VII) (Annexin-7) (Synexin) | |||
| Slit homolog 2 protein (Slit-2) [Cleaved into: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product] | Secreted | ||
| Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3) | |||
| Protein TFG (TRK-fused gene protein) | lateral sclerosis amyotrophic lateral sclerosis | Endoplasmic reticulum | |
| Zinc finger and BTB domain-containing protein 7A (Factor binding IST protein 1) (FBI-1) (Factor that binds to inducer of short transcripts protein 1) (HIV-1 1st-binding protein 1) (Leukemia/lymphoma-related factor) (POZ and Krueppel erythroid myeloid ontogenic factor) (POK erythroid myeloid ontogenic factor) (Pokemon) (Pokemon 1) (TTF-I-interacting peptide 21) (TIP21) (Zinc finger protein 857A) | Nucleus | ||
| T-cell leukemia homeobox protein 3 (Homeobox protein Hox-11L2) | Nucleus | ||
| Alpha-2-macroglobulin receptor-associated protein (Alpha-2-MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) | Rough endoplasmic reticulum lumen | ||
| Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (SINK) (p65-interacting inhibitor of NF-kappa-B) | Nucleus | ||
| Carboxypeptidase A5 (EC 3.4.17.-) | autism spectrum disorder | Secreted | |
| Cyclin-A2 (Cyclin-A) (Cyclin A) | Nucleus | ||
| BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (hBACURD3) (BTB/POZ domain-containing protein KCTD10) (Potassium channel tetramerization domain-containing protein 10) | Nucleus | ||
| Charged multivesicular body protein 1a (Chromatin-modifying protein 1a) (CHMP1a) (Vacuolar protein sorting-associated protein 46-1) (Vps46-1) (hVps46-1) | pontocerebellar hypoplasia | ||
| Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1) | |||
| 40S ribosomal protein S11 (Small ribosomal subunit protein uS17) | |||
| DnaJ homolog subfamily C member 30, mitochondrial (Williams-Beuren syndrome chromosomal region 18 protein) | Mitochondrion inner membrane | ||
| 60S ribosomal protein L15 (Large ribosomal subunit protein eL15) | Membrane | ||
| Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha mannosidase 6A8B) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1) | Cytoplasm | ||
| 26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (Antisecretory factor 1) (AF) (ASF) (Multiubiquitin chain-binding protein) | |||
| TOM1-like protein 1 (Src-activating and signaling molecule protein) (Target of Myb-like protein 1) | Golgi apparatus, Golgi stack | ||
| Beta-casein | Secreted. | ||
| Torsin-1A-interacting protein 1 (Lamin-associated protein 1B) (LAP1B) | Nucleus inner membrane | ||
| Kappa-casein | Secreted. | ||
| Protein SON (Bax antagonist selected in saccharomyces 1) (BASS1) (Negative regulatory element-binding protein) (NRE-binding protein) (Protein DBP-5) (SON3) | Nucleus speckle | ||
| Polyglutamine-binding protein 1 (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38) (Polyglutamine tract-binding protein 1) | Nucleus | ||
| Immunoglobulin lambda-like polypeptide 5 (G lambda-1) (Germline immunoglobulin lambda 1) | Secreted | ||
| Coronin-1B (Coronin-2) | Cytoplasm, cytoskeleton | ||
| Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8) | |||
| Casein kinase II subunit beta (CK II beta) (Phosvitin) (Protein G5a) | |||
| Protein SSX2 (Cancer/testis antigen 5.2) (CT5.2) (Synovial sarcoma, X breakpoint 2) (Tumor antigen HOM-MEL-40) | Nucleus. | ||
| Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1) | Cytoplasm, cytoskeleton | ||
| Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosomal region candidate gene 1 protein) (Alveolar soft part sarcoma locus) (Renal papillary cell carcinoma protein 17) (UBX domain-containing protein 9) | Endomembrane system | ||
| Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP) | lateral sclerosis amyotrophic lateral sclerosis | Cytoplasm, cytosol | |
| Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (HEBP1) (Nuclear factor, erythroid derived 2, like 2) | Cytoplasm, cytosol | ||
| Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2) | Microsome membrane | ||
| Nucleolar protein 14 (Nucleolar complex protein 14) | Nucleus, nucleolus | ||
| Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12) (Amplified in liver cancer protein 1) | Nucleus | ||
| Alpha-S1-casein [Cleaved into: Casoxin-D] | Secreted. | ||
| Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta) | |||
| Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog) | Cytoplasm | ||
| DNA endonuclease RBBP8 (EC 3.1.-.-) (CtBP-interacting protein) (CtIP) (Retinoblastoma-binding protein 8) (RBBP-8) (Retinoblastoma-interacting protein and myosin-like) (RIM) (Sporulation in the absence of SPO11 protein 2 homolog) (SAE2) | Nucleus | ||
| Rhombotin-1 (Cysteine-rich protein TTG-1) (LIM domain only protein 1) (LMO-1) (T-cell translocation protein 1) | Nucleus | ||
| Splicing factor 3B subunit 5 (SF3b5) (Pre-mRNA-splicing factor SF3b 10 kDa subunit) | Nucleus | ||
| Methyl-CpG-binding domain protein 1 (CXXC-type zinc finger protein 3) (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1) | Nucleus | ||
| Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK) | Cytoplasm | ||
| Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific peptidase 48) (Ubiquitin-specific protease 48) (Ubiquitin-specific-processing protease 48) | Cytoplasm | ||
| Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (hFAN1) (Myotubularin-related protein 15) | autism spectrum disorder | Nucleus | |
| Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1) | pontocerebellar hypoplasia | Cytoplasm | |
| THO complex subunit 2 (Tho2) (hTREX120) | Nucleus | ||
| Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated) | Nucleus | ||
| Flotillin-1 | Cell membrane | ||
| Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1) | Nucleus | ||
| Testis-specific serine/threonine-protein kinase 6 (TSK-6) (TSSK-6) (Testis-specific kinase 6) (EC 2.7.11.1) (Cancer/testis antigen 72) (CT72) (Serine/threonine-protein kinase SSTK) (Small serine/threonine kinase) | |||
| Ubinuclein-1 (HIRA-binding protein) (Protein VT4) (Ubiquitously expressed nuclear protein) | |||
| Fibroblast growth factor 14 (FGF-14) (Fibroblast growth factor homologous factor 4) (FHF-4) | autosomal dominant cerebellar ataxia | Nucleus | |
| Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7) | Cytoplasm | ||
| LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4) | |||
| Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) | Nucleus | ||
| Fanconi anemia group D2 protein (Protein FACD2) | Nucleus | ||
| Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2) | Nucleus | ||
| Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1) | Nucleus, nucleolus | ||
| Protein HID1 (Down-regulated in multiple cancers 1) (HID1 domain-containing protein) (Protein hid-1 homolog) | Cytoplasm | ||
| Regulator of G-protein signaling 17 (RGS17) | Membrane | ||
| DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-) | Nucleus | ||
| N-acylneuraminate cytidylyltransferase (EC 2.7.7.43) (CMP-N-acetylneuraminic acid synthase) (CMP-NeuNAc synthase) | Nucleus | ||
| NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier) | Cytoplasm | ||
| Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha) | Cytoplasm | ||
| Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3] | Cell junction | ||
| E3 ubiquitin-protein ligase UBR1 (EC 2.3.2.27) (N-recognin-1) (RING-type E3 ubiquitin transferase UBR1) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3-alpha-I) | Cytoplasm, cytosol | ||
| Transmembrane emp24 domain-containing protein 9 (GMP25) (Glycoprotein 25L2) (p24 family protein alpha-2) (p24alpha2) (p25) | Endoplasmic reticulum membrane | ||
| Voltage-dependent anion-selective channel protein 3 (VDAC-3) (hVDAC3) (Outer mitochondrial membrane protein porin 3) | Mitochondrion outer membrane. | ||
| Armadillo repeat-containing protein 8 | Nucleus | ||
| Peroxisomal membrane protein 11B (Peroxin-11B) (Peroxisomal biogenesis factor 11B) (Protein PEX11 homolog beta) (PEX11-beta) | Peroxisome membrane | ||
| Mitochondrial import receptor subunit TOM40 homolog (Protein Haymaker) (Translocase of outer membrane 40 kDa subunit homolog) (p38.5) | Mitochondrion outer membrane | ||
| Mitofusin-1 (EC 3.6.5.-) (Fzo homolog) (Transmembrane GTPase MFN1) | Mitochondrion outer membrane | ||
| Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (JV4-1) (Mad-related protein 1) (SMAD family member 1) (SMAD 1) (Smad1) (hSMAD1) (Transforming growth factor-beta-signaling protein 1) (BSP-1) | Cytoplasm | ||
| Secreted frizzled-related protein 4 (sFRP-4) (Frizzled protein, human endometrium) (FrpHE) | Secreted | ||
| Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome-c reductase complex core protein 2) | Mitochondrion inner membrane | ||
| AN1-type zinc finger protein 2B (Arsenite-inducible RNA-associated protein-like protein) (AIRAP-like protein) | Endoplasmic reticulum membrane | ||
| Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325) | Cell membrane | ||
| Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez) | Cytoplasm | ||
| Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kinase activator protein 1) (TKA-1) | Endomembrane system | ||
| Vacuolar protein sorting-associated protein 13C | Parkinson disease | Mitochondrion outer membrane | |
| Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2) | Nucleus | ||
| Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-) (KCCR13L) | Cell membrane | ||
| Saitohin | Cytoplasm | ||
| ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein) | Mitochondrion inner membrane | ||
| Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg) | Membrane | ||
| Sialic acid synthase (N-acetylneuraminate synthase) (EC 2.5.1.56) (N-acetylneuraminate-9-phosphate synthase) (EC 2.5.1.57) (N-acetylneuraminic acid phosphate synthase) (N-acetylneuraminic acid synthase) | |||
| Tubulin-specific chaperone D (Beta-tubulin cofactor D) (tfcD) (SSD-1) (Tubulin-folding cofactor D) | Cell junction, tight junction | ||
| Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2) | Cell projection, cilium | ||
| Selenoprotein S (SelS) (VCP-interacting membrane protein) | Endoplasmic reticulum membrane | ||
| Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1) | Cytoplasm, cytoskeleton | ||
| Alkaline phosphatase, placental type (EC 3.1.3.1) (Alkaline phosphatase Regan isozyme) (Placental alkaline phosphatase 1) (PLAP-1) | Cell membrane | ||
| Cathepsin L2 (EC 3.4.22.43) (Cathepsin U) (Cathepsin V) | Lysosome | ||
| C-type lectin domain family 11 member A (C-type lectin superfamily member 3) (Lymphocyte secreted C-type lectin) (Osteolectin) (Stem cell growth factor) (p47) | Cytoplasm | ||
| Unconventional myosin-VIIa | Cytoplasm | ||
| Protein FAM74A4/A6 | |||
| Plexin domain-containing protein 2 (Tumor endothelial marker 7-related protein) | Membrane | ||
| Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Solute carrier family 15 member 2 (Kidney H(+)/peptide cotransporter) (Oligopeptide transporter, kidney isoform) (Peptide transporter 2) | Cell membrane | ||
| Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1) | |||
| CD99 antigen-like protein 2 (MIC2-like protein 1) (CD antigen CD99) | Cell membrane | ||
| Axin-1 (Axis inhibition protein 1) (hAxin) | Cytoplasm | ||
| Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas)) | Cytoplasm | ||
| Fructose-1,6-bisphosphatase 1 (FBPase 1) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 1) (Liver FBPase) | |||
| Phospholipase D3 (PLD 3) (EC 3.1.4.4) (Choline phosphatase 3) (HindIII K4L homolog) (Hu-K4) (Phosphatidylcholine-hydrolyzing phospholipase D3) | autosomal dominant cerebellar ataxia | Endoplasmic reticulum membrane | |
| Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Cell cycle control protein TS11) (Glutamine-dependent asparagine synthetase) | |||
| Tetraspanin-17 (Tspan-17) (F-box only protein 23) (Tetraspan protein SB134) (Transmembrane 4 superfamily member 17) | Membrane | ||
| Aspartate aminotransferase, cytoplasmic (cAspAT) (EC 2.6.1.1) (EC 2.6.1.3) (Cysteine aminotransferase, cytoplasmic) (Cysteine transaminase, cytoplasmic) (cCAT) (Glutamate oxaloacetate transaminase 1) (Transaminase A) | Cytoplasm | ||
| Ly6/PLAUR domain-containing protein 3 (GPI-anchored metastasis-associated protein C4.4A homolog) (Matrigel-induced gene C4 protein) (MIG-C4) | Cell membrane | ||
| SPARC-like protein 1 (High endothelial venule protein) (Hevin) (MAST 9) | Secreted, extracellular space, extracellular matrix | ||
| Toll-like receptor 4 (hToll) (CD antigen CD284) | Cell membrane | ||
| Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed] | Nucleus | ||
| Proteasomal ubiquitin receptor ADRM1 (110 kDa cell membrane glycoprotein) (Gp110) (Adhesion-regulating molecule 1) (ARM-1) (Proteasome regulatory particle non-ATPase 13) (hRpn13) (Rpn13 homolog) | Cytoplasm | ||
| 28S ribosomal protein S22, mitochondrial (MRP-S22) (S22mt) (Mitochondrial small ribosomal subunit protein mS22) | Mitochondrion | ||
| SURP and G-patch domain-containing protein 2 (Arginine/serine-rich-splicing factor 14) (Splicing factor, arginine/serine-rich 14) | Nucleus | ||
| Protein FAM98A | |||
| DnaJ homolog subfamily B member 11 (APOBEC1-binding protein 2) (ABBP-2) (DnaJ protein homolog 9) (ER-associated DNAJ) (ER-associated Hsp40 co-chaperone) (Endoplasmic reticulum DNA J domain-containing protein 3) (ER-resident protein ERdj3) (ERdj3) (ERj3p) (HEDJ) (Human DnaJ protein 9) (hDj-9) (PWP1-interacting protein 4) | Endoplasmic reticulum lumen | ||
| ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70) | Peroxisome membrane | ||
| Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (hPNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase) | Cytoplasm | ||
| La-related protein 1 (La ribonucleoprotein domain family member 1) | Cytoplasm | ||
| Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10] | Cytoplasm. | ||
| Ribosome-binding protein 1 (180 kDa ribosome receptor homolog) (RRp) (ES/130-related protein) (Ribosome receptor protein) | Endoplasmic reticulum membrane | ||
| Interleukin enhancer-binding factor 3 (Double-stranded RNA-binding protein 76) (DRBP76) (M-phase phosphoprotein 4) (MPP4) (Nuclear factor associated with dsRNA) (NFAR) (Nuclear factor of activated T-cells 90 kDa) (NF-AT-90) (Translational control protein 80) (TCP80) | Nucleus, nucleolus | ||
| Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex) | Nucleus | ||
| BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains) | Cytoplasm. | ||
| ELAV-like protein 2 (ELAV-like neuronal protein 1) (Hu-antigen B) (HuB) (Nervous system-specific RNA-binding protein Hel-N1) | |||
| AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein) | |||
| 39S ribosomal protein L10, mitochondrial (L10mt) (MRP-L10) (39S ribosomal protein L8, mitochondrial) (L8mt) (MRP-L8) (Mitochondrial large ribosomal subunit protein uL10m) | Mitochondrion | ||
| Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.15) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) | Mitochondrion | ||
| Actin, aortic smooth muscle (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form] | Cytoplasm, cytoskeleton. | ||
| Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF) | Cytoplasm | ||
| Rho GTPase-activating protein 1 (CDC42 GTPase-activating protein) (GTPase-activating protein rhoGAP) (Rho-related small GTPase protein activator) (Rho-type GTPase-activating protein 1) (p50-RhoGAP) | Cytoplasm. | ||
| Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) | Nucleus. | ||
| Serrate RNA effector molecule homolog (Arsenite-resistance protein 2) | Nucleus, nucleoplasm | ||
| cAMP-dependent protein kinase type I-beta regulatory subunit | Cell membrane | ||
| 60S ribosomal protein L3 (HIV-1 TAR RNA-binding protein B) (TARBP-B) (Large ribosomal subunit protein uL3) | Nucleus, nucleolus | ||
| BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (hBACURD2) (BTB/POZ domain-containing protein TNFAIP1) (Protein B12) (Tumor necrosis factor, alpha-induced protein 1, endothelial) | |||
| T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding) | Cytoplasm | ||
| 26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG) | Cytoplasm | ||
| 26S proteasome regulatory subunit 4 (P26s4) (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1) | Cytoplasm | ||
| Amyloid-beta A4 precursor protein-binding family A member 3 (Adapter protein X11gamma) (Neuron-specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) | Cytoplasm, perinuclear region | ||
| Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/B') (SmB/B') | Cytoplasm, cytosol | ||
| RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity) | Nucleus | ||
| FAST kinase domain-containing protein 4 (Cell cycle progression restoration protein 2) (Cell cycle progression protein 2) (Protein TBRG4) (Transforming growth factor beta regulator 4) | Mitochondrion matrix | ||
| COMM domain-containing protein 1 (Protein Murr1) | Nucleus | ||
| 2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4) | Mitochondrion matrix | ||
| Fumarylacetoacetase (FAA) (EC 3.7.1.2) (Beta-diketonase) (Fumarylacetoacetate hydrolase) | |||
| G-rich sequence factor 1 (GRSF-1) | Cytoplasm | ||
| 28S ribosomal protein S9, mitochondrial (MRP-S9) (S9mt) (Mitochondrial small ribosomal subunit protein uS9m) | Mitochondrion | ||
| Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1) | |||
| Seizure 6-like protein | Endoplasmic reticulum membrane | ||
| Poly(rC)-binding protein 2 (Alpha-CP2) (Heterogeneous nuclear ribonucleoprotein E2) (hnRNP E2) | Nucleus | ||
| Galanin-like peptide | Secreted. | ||
| Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha) | Nucleus. | ||
| Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1) | Cell membrane | ||
| Nuclear pore complex protein Nup93 (93 kDa nucleoporin) (Nucleoporin Nup93) | Nucleus membrane | ||
| Follicular dendritic cell secreted peptide (FDC secreted protein) (FDC-SP) | Secreted. | ||
| Protein LYRIC (3D3/LYRIC) (Astrocyte elevated gene-1 protein) (AEG-1) (Lysine-rich CEACAM1 co-isolated protein) (Metadherin) (Metastasis adhesion protein) | Endoplasmic reticulum membrane | ||
| A disintegrin and metalloproteinase with thrombospondin motifs 3 (ADAM-TS 3) (ADAM-TS3) (ADAMTS-3) (EC 3.4.24.-) (Procollagen II N-proteinase) (PC II-NP) (Procollagen II amino propeptide-processing enzyme) | Secreted, extracellular space, extracellular matrix | ||
| Putative uncharacterized protein ARHGAP5-AS1 (ARHGAP5 antisense RNA 1) (ARHGAP5 antisense gene protein 1) | |||
| RNA-binding protein 41 (RNA-binding motif protein 41) | |||
| Adenosylhomocysteinase (AdoHcyase) (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) | Cytoplasm | ||
| Prostate androgen-regulated mucin-like protein 1 (PARM-1) | Cell membrane | ||
| HRAS-like suppressor 2 (EC 2.3.1.-) (EC 3.1.1.-) | |||
| AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) | Cell membrane | ||
| Mitochondrial pyruvate carrier 2 (Brain protein 44) | Mitochondrion inner membrane | ||
| Signal recognition particle 14 kDa protein (SRP14) (18 kDa Alu RNA-binding protein) | Cytoplasm. | ||
| Polymerase delta-interacting protein 2 (38 kDa DNA polymerase delta interaction protein) (p38) | Nucleus | ||
| 40S ribosomal protein S16 (Small ribosomal subunit protein uS9) | |||
| Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) | Cell junction, synapse, postsynaptic cell membrane | ||
| Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta-hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta-dioxygenase) | Isoform 1: Endoplasmic reticulum membrane | ||
| Sulfotransferase 1A1 (ST1A1) (EC 2.8.2.1) (Aryl sulfotransferase 1) (HAST1/HAST2) (Phenol sulfotransferase 1) (Phenol-sulfating phenol sulfotransferase 1) (P-PST 1) (ST1A3) (Thermostable phenol sulfotransferase) (Ts-PST) | Cytoplasm. | ||
| DNA (cytosine-5)-methyltransferase 3B (Dnmt3b) (EC 2.1.1.37) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB) | Nucleus | ||
| Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1) | Cytoplasm, cytoskeleton | ||
| Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3); Procollagen glycosyltransferase (EC 2.4.1.50) (EC 2.4.1.66) (Galactosylhydroxylysine-glucosyltransferase) (Procollagen galactosyltransferase) (Procollagen glucosyltransferase)] | Rough endoplasmic reticulum | ||
| Amyloid-beta A4 precursor protein-binding family B member 2 (Protein Fe65-like 1) | |||
| Exosome component 10 (EC 3.1.13.-) (Autoantigen PM/Scl 2) (P100 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 100 kDa) (PM/Scl-100) (Polymyositis/scleroderma autoantigen 2) | |||
| Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase) | |||
| Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) | lateral sclerosis multiple sclerosis | Cytoplasm, cell cortex | |
| Sorting and assembly machinery component 50 homolog (Transformation-related gene 3 protein) (TRG-3) | Mitochondrion outer membrane | ||
| LanC-like protein 2 (Testis-specific adriamycin sensitivity protein) | Nucleus | ||
| 40S ribosomal protein S25 (Small ribosomal subunit protein eS25) | |||
| Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) | Cytoplasm | ||
| TRMT1-like protein (EC 2.1.1.-) | |||
| Importin subunit alpha-7 (Karyopherin subunit alpha-6) | |||
| Protein RRP5 homolog (NF-kappa-B-binding protein) (NFBP) (Programmed cell death protein 11) | Nucleus, nucleolus | ||
| Matrix-remodeling-associated protein 5 (Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan) (Adlican) | autism spectrum disorder | Secreted | |
| 39S ribosomal protein L43, mitochondrial (L43mt) (MRP-L43) (Mitochondrial large ribosomal subunit protein mL43) (Mitochondrial ribosomal protein bMRP36a) | Mitochondrion | ||
| Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I) | Mitochondrion matrix. | ||
| Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) | Huntington disease lateral sclerosis amyotrophic lateral sclerosis | Cytoplasm, cytosol | |
| Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (Centaurin-delta-1) (Cnt-d1) (Protein PARX) | Cytoplasm | ||
| Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) | Cytoplasm | ||
| G1/S-specific cyclin-E1 | Nucleus | ||
| 60S ribosomal protein L37a (Large ribosomal subunit protein eL43) | |||
| Importin subunit alpha-6 (Karyopherin subunit alpha-5) | Cytoplasm. | ||
| BTB/POZ domain-containing protein KCTD17 | Cytoplasm | ||
| Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) | Nucleus, nuclear pore complex | ||
| ATPase family AAA domain-containing protein 3A | Mitochondrion inner membrane | ||
| Cold-inducible RNA-binding protein (A18 hnRNP) (Glycine-rich RNA-binding protein CIRP) | Nucleus, nucleoplasm | ||
| Endogenous retrovirus group 3 member 1 Env polyprotein (ERV-3 envelope protein) (ERV3 envelope protein) (ERV3-1 envelope protein) (Envelope polyprotein) (HERV-R envelope protein) (ERV-R envelope protein) (HERV-R_7q21.2 provirus ancestral Env polyprotein) [Cleaved into: Surface protein (SU); Transmembrane protein (TM)] | Virion. | ||
| THO complex subunit 4 (Tho4) (Ally of AML-1 and LEF-1) (Aly/REF export factor) (Transcriptional coactivator Aly/REF) (bZIP-enhancing factor BEF) | Nucleus | ||
| Tumor necrosis factor ligand superfamily member 10 (Apo-2 ligand) (Apo-2L) (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD antigen CD253) | Cell membrane | ||
| Peripherin (Neurofilament 4) | |||
| Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (hTRA2-beta) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B) | Nucleus | ||
| Myosin-7B (Antigen MLAA-21) (Myosin cardiac muscle beta chain) (Myosin heavy chain 7B, cardiac muscle beta isoform) (Slow A MYH14) | Membrane | ||
| Ubiquitin-conjugating enzyme E2 D3 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D3) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2(17)KB 3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (Ubiquitin-protein ligase D3) | Cell membrane | ||
| Probable threonine protease PRSS50 (EC 3.4.25.-) (Cancer/testis antigen 20) (Serine protease 50) (Testis-specific protease-like protein 50) | Endoplasmic reticulum | ||
| Protein disulfide-isomerase A6 (EC 5.3.4.1) (Endoplasmic reticulum protein 5) (ER protein 5) (ERp5) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7) | Endoplasmic reticulum lumen | ||
| CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] | Cytoplasm | ||
| MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAP-K2) (MAPKAPK-2) (MK-2) (MK2) (EC 2.7.11.1) | Cytoplasm | ||
| Angiomotin | Cell junction, tight junction | ||
| Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP) | Nucleus speckle | ||
| 7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-) (Bicoid-interacting protein 3 homolog) (Bin3 homolog) | |||
| M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A) | |||
| 40S ribosomal protein S3a (Small ribosomal subunit protein eS1) (v-fos transformation effector protein) (Fte-1) | Cytoplasm | ||
| Putative RNA-binding protein Luc7-like 2 | Nucleus speckle | ||
| Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 subunit 8) (eIF3 p110) | Cytoplasm | ||
| Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup88) | Nucleus, nuclear pore complex. | ||
| 60S ribosomal protein L3-like (Large ribosomal subunit protein uL3-like) | |||
| Actin-related protein 2 (Actin-like protein 2) | Cytoplasm, cytoskeleton | ||
| Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90) | Cell membrane | ||
| Sodium channel protein type 1 subunit alpha (Sodium channel protein brain I subunit alpha) (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) | Cell membrane | ||
| E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33) | Nucleus | ||
| Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) | Isoform 2: Cytoplasm, cytoskeleton | ||
| ATP synthase subunit beta, mitochondrial (EC 7.1.2.2) (ATP synthase F1 subunit beta) | Mitochondrion inner membrane | ||
| 28S ribosomal protein S21, mitochondrial (MRP-S21) (S21mt) (Mitochondrial small ribosomal subunit protein bS21m) | Mitochondrion | ||
| Nuclear envelope pore membrane protein POM 121C (Nuclear pore membrane protein 121-2) (POM121-2) (Pore membrane protein of 121 kDa C) | Nucleus, nuclear pore complex | ||
| ADP/ATP translocase 3 (ADP,ATP carrier protein 3) (ADP,ATP carrier protein, isoform T2) (ANT 2) (Adenine nucleotide translocator 3) (ANT 3) (Solute carrier family 25 member 6) [Cleaved into: ADP/ATP translocase 3, N-terminally processed] | |||
| 60S ribosomal protein L7a (Large ribosomal subunit protein eL8) (PLA-X polypeptide) (Surfeit locus protein 3) | |||
| Serine--tRNA ligase, mitochondrial (EC 6.1.1.11) (SerRSmt) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase) | Mitochondrion matrix | ||
| Spectrin beta chain, non-erythrocytic 2 (Beta-III spectrin) (Spinocerebellar ataxia 5 protein) | autosomal dominant cerebellar ataxia autosomal recessive cerebellar ataxia | Cytoplasm, cytoskeleton | |
| Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (Hp95) | Cytoplasm, cytosol | ||
| Lysine-specific demethylase hairless (EC 1.14.11.-) | Nucleus. | ||
| Elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein) (p150) | Cytoplasm | ||
| BAG family molecular chaperone regulator 5 (BAG-5) (Bcl-2-associated athanogene 5) | |||
| U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) (Serologically defined breast cancer antigen NY-BR-99) (U4/U6 snRNP 61 kDa protein) (Protein 61K) (hPrp31) | Nucleus | ||
| Glutaminyl-peptide cyclotransferase (EC 2.3.2.5) (Glutaminyl cyclase) (QC) (sQC) (Glutaminyl-tRNA cyclotransferase) (Glutamyl cyclase) (EC) | Secreted | ||
| Protein bicaudal D homolog 1 (Bic-D 1) | Golgi apparatus. | ||
| 28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt) (Mitochondrial small ribosomal subunit protein uS7m) (bMRP-27a) (bMRP27a) | Mitochondrion | ||
| Heterogeneous nuclear ribonucleoprotein U-like protein 2 (Scaffold-attachment factor A2) (SAF-A2) | Nucleus | ||
| Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA-binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1) | Cytoplasm | ||
| Sodium channel subunit beta-4 | Cell membrane | ||
| Protein pelota homolog (EC 3.1.-.-) | Nucleus | ||
| Pregnancy-specific beta-1-glycoprotein 1 (PS-beta-G-1) (PSBG-1) (Pregnancy-specific glycoprotein 1) (CD66 antigen-like family member F) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (CD antigen CD66f) | Secreted | ||
| Cytoplasmic dynein 1 light intermediate chain 1 (LIC1) (Dynein light chain A) (DLC-A) (Dynein light intermediate chain 1, cytosolic) | Cytoplasm | ||
| Protein Mis18-beta (Cancer/testis antigen 86) (CT86) (Opa-interacting protein 5) (OIP-5) | Nucleus | ||
| Serine/arginine-rich splicing factor 5 (Delayed-early protein HRS) (Pre-mRNA-splicing factor SRP40) (Splicing factor, arginine/serine-rich 5) | Nucleus. | ||
| Serine/arginine-rich splicing factor 9 (Pre-mRNA-splicing factor SRp30C) (Splicing factor, arginine/serine-rich 9) | Nucleus | ||
| Delphilin (Glutamate receptor, ionotropic, delta 2-interacting protein 1) | Cell junction, synapse, postsynaptic cell membrane | ||
| Transcriptional activator protein Pur-beta (Purine-rich element-binding protein B) | Nucleus | ||
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (EC 1.6.99.3) (EC 7.1.1.2) (Complex I-30kD) (CI-30kD) (NADH-ubiquinone oxidoreductase 30 kDa subunit) | Parkinson disease | Mitochondrion inner membrane. | |
| Glutamate receptor ionotropic, delta-2 (GluD2) (GluR delta-2 subunit) | autosomal recessive cerebellar ataxia | Cell membrane | |
| Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP) | Cytoplasm | ||
| Keratin-associated protein 12-2 (High sulfur keratin-associated protein 12.2) (Keratin-associated protein 12.2) | |||
| Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2) | Cytoplasm | ||
| Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I) | Nucleus. | ||
| Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein) | |||
| Protein arginine N-methyltransferase 5 (EC 2.1.1.320) (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed] | Cytoplasm | ||
| Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein) (DLC-1) (HP protein) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) | |||
| Coiled-coil domain-containing protein 172 | Cytoplasm | ||
| Thioredoxin domain-containing protein 5 (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Thioredoxin-like protein p46) | Endoplasmic reticulum lumen | ||
| HCLS1-associated protein X-1 (HS1-associating protein X-1) (HAX-1) (HS1-binding protein 1) (HSP1BP-1) | Mitochondrion | ||
| 39S ribosomal protein L44, mitochondrial (L44mt) (MRP-L44) (EC 3.1.26.-) (Mitochondrial large ribosomal subunit protein mL44) | Mitochondrion | ||
| Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase) | |||
| Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1) | Nucleus | ||
| Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5) | Mitochondrion | ||
| Kelch-like protein 11 | |||
| Myelin-associated neurite-outgrowth inhibitor (Mani) (p20) | Cytoplasm, perinuclear region | ||
| 60S ribosomal protein L22 (EBER-associated protein) (EAP) (Epstein-Barr virus small RNA-associated protein) (Heparin-binding protein HBp15) (Large ribosomal subunit protein eL22) | |||
| Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) | Membrane | ||
| Ubiquitin-associated protein 2-like (Protein NICE-4) | |||
| TIP41-like protein (Putative MAPK-activating protein PM10) (Type 2A-interacting protein) (TIP) | Cytoplasm | ||
| tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (mRNA methyladenosine-N(1)-methyltransferase non-catalytic subunit TRM6) (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6) | Nucleus | ||
| KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68) | spinal muscular atrophy | Nucleus | |
| 40S ribosomal protein S7 (Small ribosomal subunit protein eS7) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| General transcription factor 3C polypeptide 5 (TF3C-epsilon) (Transcription factor IIIC 63 kDa subunit) (TFIIIC 63 kDa subunit) (TFIIIC63) (Transcription factor IIIC subunit epsilon) | Nucleus. | ||
| Lysosomal acid phosphatase (LAP) (EC 3.1.3.2) | Lysosome membrane | ||
| 4F2 cell-surface antigen heavy chain (4F2hc) (4F2 heavy chain antigen) (Lymphocyte activation antigen 4F2 large subunit) (Solute carrier family 3 member 2) (CD antigen CD98) | |||
| Butyrophilin subfamily 2 member A2 | Membrane | ||
| Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein) | Membrane | ||
| RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed] | Nucleus | ||
| Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4) | Nucleus | ||
| Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5) | Cytoplasm, cytoskeleton | ||
| MKI67 FHA domain-interacting nucleolar phosphoprotein (Nucleolar phosphoprotein Nopp34) (Nucleolar protein interacting with the FHA domain of pKI-67) (hNIFK) | |||
| Suppressor of fused homolog (SUFUH) | autosomal recessive cerebellar ataxia | Cytoplasm | |
| Cell cycle and apoptosis regulator protein 2 (Cell division cycle and apoptosis regulator protein 2) (DBIRD complex subunit KIAA1967) (Deleted in breast cancer gene 1 protein) (DBC-1) (DBC.1) (NET35) (p30 DBC) | Nucleus | ||
| GA-binding protein subunit beta-1 (GABP subunit beta-1) (GABPB-1) (GABP subunit beta-2) (GABPB-2) (Nuclear respiratory factor 2) (Transcription factor E4TF1-47) (Transcription factor E4TF1-53) | Nucleus. | ||
| DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I) | Nucleus, nucleolus | ||
| Probable rRNA-processing protein EBP2 (EBNA1-binding protein 2) (Nucleolar protein p40) | Nucleus, nucleolus | ||
| Protein FAM50B (Protein XAP-5-like) | |||
| 28S ribosomal protein S15, mitochondrial (MRP-S15) (S15mt) (Mitochondrial small ribosomal subunit protein uS15m) | Mitochondrion | ||
| Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803) | Nucleus speckle. | ||
| RNA-binding protein 45 (Developmentally-regulated RNA-binding protein 1) (RB-1) (RNA-binding motif protein 45) | Cytoplasm | ||
| Dynein light chain roadblock-type 1 (Bithoraxoid-like protein) (BLP) (Dynein light chain 2A, cytoplasmic) (Dynein-associated protein Km23) (Roadblock domain-containing protein 1) | Cytoplasm, cytoskeleton. | ||
| Phosphorylated adapter RNA export protein (RNA U small nuclear RNA export adapter protein) | Nucleus, nucleoplasm | ||
| Dynein light chain Tctex-type 1 (Protein CW-1) (T-complex testis-specific protein 1 homolog) | Golgi apparatus | ||
| Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220) | Parkinson disease | ||
| Fatty acid-binding protein, brain (Brain lipid-binding protein) (BLBP) (Brain-type fatty acid-binding protein) (B-FABP) (Fatty acid-binding protein 7) (Mammary-derived growth inhibitor related) | Cytoplasm. | ||
| Peptidase inhibitor 16 (PI-16) (Cysteine-rich secretory protein 9) (CRISP-9) (PSP94-binding protein) (CD antigen CD364) | Secreted | ||
| Astrocytic phosphoprotein PEA-15 (15 kDa phosphoprotein enriched in astrocytes) (Phosphoprotein enriched in diabetes) (PED) | |||
| 60S ribosomal protein L13a (23 kDa highly basic protein) (Large ribosomal subunit protein uL13) | Cytoplasm | ||
| Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14) | |||
| Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor) | Membrane | ||
| Fatty acid desaturase 6 (EC 1.14.19.-) | Membrane | ||
| Protein FAM208B | |||
| 40S ribosomal protein S18 (Ke-3) (Ke3) (Small ribosomal subunit protein uS13) | Cytoplasm. | ||
| 60S ribosomal protein L7 (Large ribosomal subunit protein uL30) | |||
| ATP synthase subunit alpha, mitochondrial (ATP synthase F1 subunit alpha) | Mitochondrion | ||
| BolA-like protein 3 | Mitochondrion | ||
| Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Zinc finger CCCH domain-containing protein 2) (Zinc finger antiviral protein) (ZAP) | |||
| 28S ribosomal protein S34, mitochondrial (MRP-S34) (S34mt) (Mitochondrial small ribosomal subunit protein mS34) | Mitochondrion | ||
| C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3) | Cytoplasm | ||
| RNA-binding protein Musashi homolog 2 (Musashi-2) | |||
| Myelin and lymphocyte protein (T-lymphocyte maturation-associated protein) | Membrane | ||
| WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein) | Nucleus | ||
| U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'') | Nucleus | ||
| AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit) | |||
| Acylglycerol kinase, mitochondrial (hAGK) (EC 2.7.1.107) (EC 2.7.1.94) (Multiple substrate lipid kinase) (HsMuLK) (MuLK) (Multi-substrate lipid kinase) | Mitochondrion inner membrane | ||
| Heterochromatin protein 1-binding protein 3 (Protein HP1-BP74) | Nucleus | ||
| N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 (EC 2.4.1.149) (Beta-1,3-N-acetylglucosaminyltransferase 1) (BGnT-1) (Beta-1,3-Gn-T1) (Beta3Gn-T1) (Beta-1,3-galactosyltransferase 7) (Beta-1,3-GalTase 7) (Beta3Gal-T7) (Beta3GalT7) (b3Gal-T7) (Beta-3-Gx-T7) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 7) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2) (BGnT-2) (Beta-1,3-Gn-T2) (Beta-1,3-N-acetylglucosaminyltransferase 2) (Beta3Gn-T2) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 7) | Golgi apparatus membrane | ||
| Elongation factor Tu, mitochondrial (EF-Tu) (P43) | Mitochondrion | ||
| Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2) | Nucleus | ||
| 3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase) (T1) | Mitochondrion | ||
| Zinc finger CCHC domain-containing protein 3 | |||
| Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS) | Mitochondrion matrix | ||
| Pentatricopeptide repeat-containing protein 1, mitochondrial | Mitochondrion | ||
| FAST kinase domain-containing protein 2, mitochondrial | Mitochondrion matrix, mitochondrion nucleoid | ||
| Fanconi anemia core complex-associated protein 100 (Fanconi anemia-associated protein of 100 kDa) | Nucleus | ||
| Alpha-centractin (Centractin) (ARP1) (Actin-RPV) (Centrosome-associated actin homolog) | Cytoplasm, cytoskeleton | ||
| Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17) (DEAD box protein p72) (DEAD box protein p82) (RNA-dependent helicase p72) | Nucleus | ||
| Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) | Cytoplasm | ||
| Kelch-like protein 3 | Cytoplasm, cytoskeleton | ||
| Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)] | |||
| 26S proteasome regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2) (Protein MSS1) | Cytoplasm | ||
| ATP-binding cassette sub-family E member 1 (2'-5'-oligoadenylate-binding protein) (HuHP68) (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) | Cytoplasm | ||
| Thioredoxin-like protein 4A (DIM1 protein homolog) (Spliceosomal U5 snRNP-specific 15 kDa protein) (Thioredoxin-like U5 snRNP protein U5-15kD) | Nucleus | ||
| 60S ribosomal protein L19 (Large ribosomal subunit protein eL19) | |||
| Collagen type IV alpha-3-binding protein (Ceramide transfer protein) (hCERT) (Goodpasture antigen-binding protein) (GPBP) (START domain-containing protein 11) (StARD11) (StAR-related lipid transfer protein 11) | Cytoplasm | ||
| Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit) | Nucleus | ||
| 40S ribosomal protein S19 (Small ribosomal subunit protein eS19) | Nucleus | ||
| Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62) (IGF-II mRNA-binding protein 2) (VICKZ family member 2) | |||
| Zinc finger protein 830 (Coiled-coil domain-containing protein 16) | Nucleus | ||
| Sentrin-specific protease 3 (EC 3.4.22.-) (SUMO-1-specific protease 3) (Sentrin/SUMO-specific protease SENP3) | Nucleus, nucleolus | ||
| Heterogeneous nuclear ribonucleoprotein L (hnRNP L) | Nucleus, nucleoplasm | ||
| Tubulin beta-6 chain (Tubulin beta class V) | Cytoplasm, cytoskeleton | ||
| Disks large-associated protein 3 (DAP-3) (PSD-95/SAP90-binding protein 3) (SAP90/PSD-95-associated protein 3) (SAPAP3) | Cell membrane | ||
| ATP-dependent DNA/RNA helicase DHX36 (EC 3.6.4.12) (EC 3.6.4.13) (DEAD/H box polypeptide 36) (DEAH-box protein 36) (G4-resolvase-1) (G4R1) (MLE-like protein 1) (RNA helicase associated with AU-rich element protein) | Nucleus | ||
| Protein arginine N-methyltransferase 1 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT1) (Interferon receptor 1-bound protein 4) | Nucleus | ||
| Vacuolar protein sorting-associated protein 37C (hVps37C) (ESCRT-I complex subunit VPS37C) | Late endosome membrane | ||
| Ubiquitin thioesterase OTUB2 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB2) (OTU domain-containing ubiquitin aldehyde-binding protein 2) (Otubain-2) (Ubiquitin-specific-processing protease OTUB2) | |||
| Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (hDTX2) (RING finger protein 58) (RING-type E3 ubiquitin transferase DTX2) | Cytoplasm | ||
| Protein FAM161B | |||
| 60S ribosomal protein L17 (60S ribosomal protein L23) (Large ribosomal subunit protein uL22) (PD-1) | |||
| Protein NipSnap homolog 2 (NipSnap2) (Glioblastoma-amplified sequence) | Cytoplasm | ||
| Serum paraoxonase/arylesterase 2 (PON 2) (EC 3.1.1.2) (EC 3.1.1.81) (Aromatic esterase 2) (A-esterase 2) (Serum aryldialkylphosphatase 2) | Membrane | ||
| Protein FAM122A | |||
| A-kinase anchor protein 11 (AKAP-11) (A-kinase anchor protein 220 kDa) (AKAP 220) (hAKAP220) (Protein kinase A-anchoring protein 11) (PRKA11) | |||
| Nuclear pore glycoprotein p62 (62 kDa nucleoporin) (Nucleoporin Nup62) | Nucleus, nuclear pore complex | ||
| BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (hBACURD1) (BTB/POZ domain-containing protein KCTD13) (Polymerase delta-interacting protein 1) (TNFAIP1-like protein) | autism spectrum disorder | Nucleus | |
| Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform (IMYPNO1) (PP2A subunit B isoform B55-gamma) (PP2A subunit B isoform PR55-gamma) (PP2A subunit B isoform R2-gamma) (PP2A subunit B isoform gamma) | |||
| DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2) | Nucleus | ||
| Protein SEC13 homolog (GATOR complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein) | Cytoplasmic vesicle, COPII-coated vesicle membrane | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (Complex I-B8) (CI-B8) (NADH-ubiquinone oxidoreductase B8 subunit) | Parkinson disease | Mitochondrion inner membrane | |
| 40S ribosomal protein S13 (Small ribosomal subunit protein uS15) | |||
| ATP synthase subunit gamma, mitochondrial (ATP synthase F1 subunit gamma) (F-ATPase gamma subunit) | Mitochondrion inner membrane | ||
| 60S ribosomal protein L7-like 1 (Large ribosomal subunit protein uL30-like 1) | |||
| 14-3-3 protein eta (Protein AS1) | |||
| La-related protein 7 (La ribonucleoprotein domain family member 7) (P-TEFb-interaction protein for 7SK stability) (PIP7S) | Nucleus, nucleoplasm | ||
| 28S ribosomal protein S18b, mitochondrial (MRP-S18-b) (Mrps18-b) (S18mt-b) (28S ribosomal protein S18-2, mitochondrial) (MRP-S18-2) (Mitochondrial small ribosomal subunit protein bS18b) (Mitochondrial small ribosomal subunit protein mS40) | Mitochondrion | ||
| Heat shock protein 105 kDa (Antigen NY-CO-25) (Heat shock 110 kDa protein) | Cytoplasm | ||
| E3 ubiquitin-protein ligase RNF19B (EC 2.3.2.31) (IBR domain-containing protein 3) (Natural killer lytic-associated molecule) (RING finger protein 19B) | Cytoplasmic granule membrane | ||
| NEDD4-binding protein 1 (N4BP1) | Nucleus, nucleolus | ||
| 60S ribosomal protein L14 (CAG-ISL 7) (Large ribosomal subunit protein eL14) | |||
| tRNA methyltransferase 10 homolog C (HBV pre-S2 trans-regulated protein 2) (Mitochondrial ribonuclease P protein 1) (Mitochondrial RNase P protein 1) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (Renal carcinoma antigen NY-REN-49) (mRNA methyladenosine-N(1)-methyltransferase) (EC 2.1.1.-) (tRNA (adenine(9)-N(1))-methyltransferase) (EC 2.1.1.218) (tRNA (guanine(9)-N(1))-methyltransferase) (EC 2.1.1.221) | Mitochondrion matrix, mitochondrion nucleoid | ||
| DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) | Cytoplasm | ||
| Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein) | Cytoplasm | ||
| NEDD8-activating enzyme E1 regulatory subunit (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1) (Amyloid protein-binding protein 1) (Proto-oncogene protein 1) | Cell membrane | ||
| 39S ribosomal protein L19, mitochondrial (L19mt) (MRP-L19) (39S ribosomal protein L15, mitochondrial) (L15mt) (MRP-L15) (Mitochondrial large ribosomal subunit protein bL19m) | Mitochondrion | ||
| Heat shock protein beta-6 (HspB6) (Heat shock 20 kDa-like protein p20) | Cytoplasm | ||
| Regulator of telomere elongation helicase 1 (EC 3.6.4.12) (Novel helicase-like) | Nucleus | ||
| Zinc finger RNA-binding protein (hZFR) (M-phase phosphoprotein homolog) | Nucleus | ||
| Tumor necrosis factor receptor superfamily member 10A (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD antigen CD261) | Membrane | ||
| Transcription initiation factor TFIID subunit 4B (Transcription initiation factor TFIID 105 kDa subunit) (TAF(II)105) (TAFII-105) (TAFII105) | Nucleus | ||
| Transcription initiation factor TFIID subunit 3 (140 kDa TATA box-binding protein-associated factor) (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (TAF(II)140) (TAF140) (TAFII-140) (TAFII140) | Nucleus | ||
| Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102) | Cytoplasm, cytosol | ||
| Transcription initiation factor TFIID subunit 8 (Protein taube nuss) (TBP-associated factor 43 kDa) (TBP-associated factor 8) (Transcription initiation factor TFIID 43 kDa subunit) (TAFII-43) (TAFII43) (hTAFII43) | Nucleus | ||
| Tubulin beta-2B chain | Cytoplasm, cytoskeleton | ||
| Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Channel-kinase 1) (Long transient receptor potential channel 7) (LTrpC-7) (LTrpC7) | lateral sclerosis amyotrophic lateral sclerosis | Membrane | |
| Ectoderm-neural cortex protein 1 (ENC-1) (Kelch-like protein 37) (Nuclear matrix protein NRP/B) (p53-induced gene 10 protein) | Nucleus matrix | ||
| Transcription initiation factor TFIID subunit 13 (Transcription initiation factor TFIID 18 kDa subunit) (TAF(II)18) (TAFII-18) (TAFII18) | Nucleus | ||
| Lysine-specific demethylase 5D (EC 1.14.11.-) (Histocompatibility Y antigen) (H-Y) (Histone demethylase JARID1D) (Jumonji/ARID domain-containing protein 1D) (Protein SmcY) | Nucleus | ||
| Histone acetyltransferase KAT6B (EC 2.3.1.48) (Histone acetyltransferase MOZ2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (MYST-4) (Monocytic leukemia zinc finger protein-related factor) | Nucleus | ||
| Ras-responsive element-binding protein 1 (RREB-1) (Finger protein in nuclear bodies) (Raf-responsive zinc finger protein LZ321) (Zinc finger motif enhancer-binding protein 1) (Zep-1) | Nucleus speckle | ||
| Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS) | Cytoplasm, cytosol | ||
| Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial (EC 6.2.1.4) (GTP-specific succinyl-CoA synthetase subunit beta) (G-SCS) (GTPSCS) (Succinyl-CoA synthetase beta-G chain) (SCS-betaG) | Mitochondrion | ||
| 39S ribosomal protein L28, mitochondrial (L28mt) (MRP-L28) (Melanoma antigen p15) (Melanoma-associated antigen recognized by T-lymphocytes) (Mitochondrial large ribosomal subunit protein bL28m) | Mitochondrion | ||
| Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta-EF hand domain-containing protein 1) | Cytoplasm | ||
| Dynactin subunit 2 (50 kDa dynein-associated polypeptide) (Dynactin complex 50 kDa subunit) (DCTN-50) (p50 dynamitin) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein) | Cytoplasm | ||
| Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II) | Mitochondrion inner membrane | ||
| Clustered mitochondria protein homolog | Cytoplasm | ||
| Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3) | episodic ataxia | Cell membrane | |
| Fibronectin type III domain-containing protein 11 | |||
| Staphylococcal nuclease domain-containing protein 1 (EC 3.1.31.1) (100 kDa coactivator) (EBNA2 coactivator p100) (Tudor domain-containing protein 11) (p100 co-activator) | Cytoplasm | ||
| LYR motif-containing protein 2 | |||
| Exosome RNA helicase MTR4 (EC 3.6.4.13) (ATP-dependent RNA helicase DOB1) (ATP-dependent RNA helicase SKIV2L2) (Superkiller viralicidic activity 2-like 2) (TRAMP-like complex helicase) | Nucleus, nucleoplasm | ||
| Transcription elongation factor A N-terminal and central domain-containing protein (TFIIS central domain-containing protein 1) | |||
| 40S ribosomal protein S17 (Small ribosomal subunit protein eS17) | |||
| Uncharacterized protein CCDC198 | |||
| Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153) | |||
| Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2) | |||
| Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+) symporter 1) (Solute carrier family 25 member 22) | Mitochondrion inner membrane | ||
| Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha) | Cytoplasm | ||
| Histone H2B type 2-E (Histone H2B-GL105) (Histone H2B.q) (H2B/q) | Nucleus | ||
| 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDE1A) (BCKDH E1-alpha) | Mitochondrion matrix. | ||
| Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) | Nucleus | ||
| Single-stranded DNA-binding protein, mitochondrial (Mt-SSB) (MtSSB) (PWP1-interacting protein 17) | Mitochondrion | ||
| WD repeat-containing protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1) | Cytoplasm, cytoskeleton | ||
| BET1 homolog (hBET1) (Golgi vesicular membrane-trafficking protein p18) | Endoplasmic reticulum membrane | ||
| FAS-associated death domain protein (FAS-associating death domain-containing protein) (Growth-inhibiting gene 3 protein) (Mediator of receptor induced toxicity) (Protein FADD) | |||
| Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) | Nucleus | ||
| Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1) | Endoplasmic reticulum lumen. | ||
| Zinc finger protein GLI2 (GLI family zinc finger protein 2) (Tax helper protein) | Nucleus | ||
| Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK) | Cytoplasm, P-body | ||
| 60S ribosomal protein L21 (Large ribosomal subunit protein eL21) | Cytoplasm, cytosol | ||
| 60S ribosomal protein L10a (CSA-19) (Large ribosomal subunit protein uL1) (Neural precursor cell expressed developmentally down-regulated protein 6) (NEDD-6) | |||
| Pyridoxal kinase (EC 2.7.1.35) (Pyridoxine kinase) | Cytoplasm. | ||
| Podocalyxin (GCTM-2 antigen) (Gp200) (Podocalyxin-like protein 1) (PC) (PCLP-1) | Apical cell membrane | ||
| Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90) | Endoplasmic reticulum membrane | ||
| Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form) (skNAC) | Cytoplasm | ||
| Cancer/testis antigen 2 (CT2) (Autoimmunogenic cancer/testis antigen NY-ESO-2) (Cancer/testis antigen 6.2) (CT6.2) (L antigen family member 1) (LAGE-1) | |||
| Protein transport protein Sec24A (SEC24-related protein A) | Cytoplasmic vesicle, COPII-coated vesicle membrane | ||
| ATP-dependent RNA helicase SUPV3L1, mitochondrial (EC 3.6.4.13) (Suppressor of var1 3-like protein 1) (SUV3-like protein 1) | Nucleus | ||
| Serine/arginine repetitive matrix protein 1 (SR-related nuclear matrix protein of 160 kDa) (SRm160) (Ser/Arg-related nuclear matrix protein) | Nucleus matrix | ||
| Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor antisera-selected protein) (hIRAS) (Imidazoline-1 receptor) (I1R) (Imidazoline-1 receptor candidate protein) (I-1 receptor candidate protein) (I1R candidate protein) | |||
| Bcl-2-interacting killer (Apoptosis inducer NBK) (BIP1) (BP4) | Endomembrane system | ||
| Ribonuclease 3 (EC 3.1.26.3) (Protein Drosha) (Ribonuclease III) (RNase III) (p241) | Nucleus | ||
| Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Cleaved into: Neuregulin-4 (NRG-4)] | Pro-neuregulin-4, membrane-bound isoform: Cell membrane | ||
| BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 | |||
| Protein argonaute-3 (Argonaute3) (hAgo3) (EC 3.1.26.n2) (Argonaute RISC catalytic component 3) (Eukaryotic translation initiation factor 2C 3) (eIF-2C 3) (eIF2C 3) | Cytoplasm, P-body | ||
| Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated Src activator) (Protein FAM120A) | Cytoplasm | ||
| 40S ribosomal protein S10 (Small ribosomal subunit protein eS10) | Cytoplasm | ||
| 40S ribosomal protein S5 (Small ribosomal subunit protein uS7) [Cleaved into: 40S ribosomal protein S5, N-terminally processed] | |||
| 40S ribosomal protein S9 (Small ribosomal subunit protein uS4) | Cytoplasm | ||
| Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (EC 3.4.11.9) (Aminopeptidase P3) (APP3) | Isoform 1: Mitochondrion | ||
| BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 | |||
| RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha) | |||
| Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77) | Nucleus. | ||
| Translocon-associated protein subunit delta (TRAP-delta) (Signal sequence receptor subunit delta) (SSR-delta) | Endoplasmic reticulum membrane | ||
| FK506-binding protein 15 (FKBP-15) (133 kDa FK506-binding protein) (133 kDa FKBP) (FKBP-133) (WASP- and FKBP-like protein) (WAFL) | Cytoplasm | ||
| Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (EC 1.14.11.4) (Lysyl hydroxylase 1) (LH1) | Rough endoplasmic reticulum membrane | ||
| Src substrate cortactin (Amplaxin) (Oncogene EMS1) | Cytoplasm, cytoskeleton | ||
| Phospholipase D2 (PLD 2) (hPLD2) (EC 3.1.4.4) (Choline phosphatase 2) (PLD1C) (Phosphatidylcholine-hydrolyzing phospholipase D2) | Membrane | ||
| Hematopoietically-expressed homeobox protein HHEX (Homeobox protein HEX) (Homeobox protein PRH) | Nucleus | ||
| Ribosome biogenesis regulatory protein homolog | Nucleus, nucleolus | ||
| Zinc finger CCHC domain-containing protein 8 (TRAMP-like complex RNA-binding factor ZCCHC8) | Nucleus, nucleoplasm | ||
| N-acetylglucosamine-1-phosphotransferase subunit gamma (GlcNAc-1-phosphotransferase subunit gamma) (UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma) | Secreted | ||
| Dermcidin (EC 3.4.-.-) (Preproteolysin) [Cleaved into: Survival-promoting peptide; DCD-1] | Secreted. | ||
| Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A) | |||
| 5'-nucleotidase domain-containing protein 2 (EC 3.1.3.-) | |||
| Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A) | |||
| Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) | Mitochondrion matrix | ||
| cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11) | Cytoplasm | ||
| GrpE protein homolog 1, mitochondrial (HMGE) (Mt-GrpE#1) | Mitochondrion matrix | ||
| Complex III assembly factor LYRM7 (LYR motif-containing protein 7) | Mitochondrion matrix | ||
| 26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (MB67-interacting protein) (MIP224) (Proteasome 26S subunit ATPase 4) (Tat-binding protein 7) (TBP-7) | Cytoplasm | ||
| Arginine-hydroxylase NDUFAF5, mitochondrial (EC 1.-.-.-) (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5) (Putative methyltransferase NDUFAF5) (EC 2.1.1.-) | Parkinson disease | Mitochondrion inner membrane | |
| 40S ribosomal protein S12 (Small ribosomal subunit protein eS12) | Cytoplasm. | ||
| Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta) | |||
| Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75) | pontocerebellar hypoplasia | Cytoplasm | |
| La-related protein 1B (La ribonucleoprotein domain family member 1B) (La ribonucleoprotein domain family member 2) (La-related protein 2) | |||
| Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11) | |||
| 26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) (26S proteasome regulatory subunit S3) (Proteasome subunit p58) | |||
| RCC1 and BTB domain-containing protein 2 (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor) (Regulator of chromosome condensation and BTB domain-containing protein 2) | Cytoplasmic vesicle, secretory vesicle, acrosome | ||
| Threonine--tRNA ligase, mitochondrial (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase-like 1) | Mitochondrion matrix | ||
| Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3) | Cytoplasm, cytosol | ||
| Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu) | Nucleus, nucleolus | ||
| Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein) | autosomal dominant cerebellar ataxia lateral sclerosis olivopontocerebellar atrophy ... amyotrophic lateral sclerosis | Cytoplasm | |
| Synaptotagmin-like protein 2 (Breast cancer-associated antigen SGA-72M) (Exophilin-4) | Isoform 1: Cytoplasm | ||
| Apoptotic chromatin condensation inducer in the nucleus (Acinus) | |||
| Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3) | |||
| FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A) | Nucleus | ||
| Sushi repeat-containing protein SRPX | Cell surface | ||
| Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed] | Cytoplasm | ||
| RNA-binding motif protein, Y chromosome, family 1 member A1 (RNA-binding motif protein 1) (RNA-binding motif protein 2) (Y chromosome RNA recognition motif 1) (hRBMY) | Nucleus | ||
| 40S ribosomal protein S3 (EC 4.2.99.18) (Small ribosomal subunit protein uS3) | Cytoplasm | ||
| RNA guanine-N7 methyltransferase activating subunit (Protein FAM103A1) (RNA guanine-7 methyltransferase activating subunit) (RNMT-activating mRNA cap methyltransferase subunit) (RNMT-activating mini protein) (RAM) | Nucleus | ||
| Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase) | Cytoplasm, perinuclear region | ||
| Hepatocyte growth factor-like protein (Macrophage stimulatory protein) (Macrophage-stimulating protein) (MSP) [Cleaved into: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain] | Secreted. | ||
| WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed] | Cytoplasm | ||
| 39S ribosomal protein L21, mitochondrial (L21mt) (MRP-L21) (Mitochondrial large ribosomal subunit protein bL21m) | Mitochondrion | ||
| Transforming growth factor beta-2 proprotein (Cetermin) (Glioblastoma-derived T-cell suppressor factor) (G-TSF) [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-2 (TGF-beta-2)] | Latency-associated peptide: Secreted, extracellular space, extracellular matrix | ||
| Tissue alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucosidase I) (Alpha-L-fucoside fucohydrolase 1) (Alpha-L-fucosidase 1) | Lysosome. | ||
| U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A) | Nucleus. | ||
| AMP deaminase 1 (EC 3.5.4.6) (AMP deaminase isoform M) (Myoadenylate deaminase) | |||
| Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8) | Cytoplasm | ||
| Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4) | Nucleus speckle | ||
| Low affinity immunoglobulin gamma Fc region receptor III-A (CD16a antigen) (Fc-gamma RIII-alpha) (Fc-gamma RIII) (Fc-gamma RIIIa) (FcRIII) (FcRIIIa) (FcR-10) (IgG Fc receptor III-2) (CD antigen CD16a) | Cell membrane | ||
| Melanoma-associated antigen D1 (MAGE tumor antigen CCF) (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) | Cytoplasm | ||
| Tubulin monoglycylase TTLL3 (EC 6.3.2.-) (HOTTL) (Tubulin--tyrosine ligase-like protein 3) | Cytoplasm, cytoskeleton | ||
| Microtubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma) | Cytoplasm, cytoskeleton | ||
| Cohesin subunit SA-1 (SCC3 homolog 1) (Stromal antigen 1) | |||
| Proteasome subunit alpha type-7 (EC 3.4.25.1) (Proteasome subunit RC6-1) (Proteasome subunit XAPC7) | Cytoplasm | ||
| 60S acidic ribosomal protein P0 (60S ribosomal protein L10E) (Large ribosomal subunit protein uL10) | Nucleus | ||
| Regulator of nonsense transcripts 1 (EC 3.6.4.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1) | |||
| TIR domain-containing adapter molecule 1 (TICAM-1) (Proline-rich, vinculin and TIR domain-containing protein B) (Putative NF-kappa-B-activating protein 502H) (Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta) (MyD88-3) (TIR domain-containing adapter protein inducing IFN-beta) | Cytoplasmic vesicle, autophagosome | ||
| Transketolase (TK) (EC 2.2.1.1) | |||
| Class E basic helix-loop-helix protein 41 (bHLHe41) (Class B basic helix-loop-helix protein 3) (bHLHb3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1) | Nucleus | ||
| Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36) | Cytoplasm | ||
| 17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3) (Short chain dehydrogenase/reductase family 47C member 1) | Cytoplasm | ||
| Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (EC 1.3.5.1) (Iron-sulfur subunit of complex II) (Ip) | Mitochondrion inner membrane | ||
| Membrane-spanning 4-domains subfamily A member 3 (CD20 antigen-like protein) (Hematopoietic-specific transmembrane protein 4) (HTm4) | Endomembrane system | ||
| Cilia- and flagella-associated protein 410 (C21orf-HUMF09G8.5) (Leucine-rich repeat-containing protein 76) (YF5/A2) | lateral sclerosis | Mitochondrion | |
| Reticulocalbin-2 (Calcium-binding protein ERC-55) (E6-binding protein) (E6BP) | Endoplasmic reticulum lumen. | ||
| Metabotropic glutamate receptor 5 (mGluR5) | Cell membrane | ||
| Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP) | Cytoplasm | ||
| Ataxin-10 (Brain protein E46 homolog) (Spinocerebellar ataxia type 10 protein) | autosomal dominant cerebellar ataxia | Cytoplasm, perinuclear region | |
| 60S ribosomal protein L9 (Large ribosomal subunit protein uL6) | |||
| Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.4.19.12) (Deubiquitinating enzyme 26) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) | Nucleus | ||
| Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG) | Cell junction | ||
| NudC domain-containing protein 3 | |||
| 40S ribosomal protein S21 (Small ribosomal subunit protein eS21) | Cytoplasm, cytosol | ||
| Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC-2) (LIC53/55) | Cytoplasm, cytoskeleton | ||
| Nuclear pore complex protein Nup160 (160 kDa nucleoporin) (Nucleoporin Nup160) | Nucleus, nuclear pore complex | ||
| Vacuolar protein sorting-associated protein 4B (EC 3.6.4.6) (Cell migration-inducing gene 1 protein) (Suppressor of K(+) transport growth defect 1) (Protein SKD1) | Prevacuolar compartment membrane | ||
| Phosphate carrier protein, mitochondrial (Phosphate transport protein) (PTP) (Solute carrier family 25 member 3) | Mitochondrion inner membrane | ||
| Tetratricopeptide repeat protein 39B (TPR repeat protein 39B) | |||
| Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) | Cytoplasm, cytoskeleton. | ||
| Eukaryotic translation initiation factor 4B (eIF-4B) | |||
| Small nuclear ribonucleoprotein Sm D2 (Sm-D2) (snRNP core protein D2) | Cytoplasm, cytosol | ||
| Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial (EC 1.2.4.1) (PDHE1-A type II) | Mitochondrion matrix. | ||
| Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8) | Cytoplasm. | ||
| Dead end protein homolog 1 (RNA-binding motif, single-stranded-interacting protein 4) | Nucleus | ||
| 60S ribosomal protein L30 (Large ribosomal subunit protein eL30) | |||
| Polyadenylate-binding protein-interacting protein 2B (PABP-interacting protein 2B) (PAIP-2B) (Poly(A)-binding protein-interacting protein 2B) | |||
| DnaJ homolog subfamily B member 6 (HHDJ1) (Heat shock protein J2) (HSJ-2) (MRJ) (MSJ-1) | Cytoplasm, perinuclear region | ||
| RING finger protein 207 | Cytoplasm | ||
| Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE) | Cytoplasm, cytosol | ||
| Mitochondrial chaperone BCS1 (h-BCS1) (BCS1-like protein) | Mitochondrion inner membrane | ||
| Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF) | Cytoplasm, cytosol | ||
| BTB/POZ domain-containing protein KCTD9 | |||
| Protein cornichon homolog 3 (CNIH-3) (Cornichon family AMPA receptor auxiliary protein 3) | Cell junction, synapse, postsynaptic cell membrane | ||
| Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (ISG-54 K) (Interferon-induced 54 kDa protein) (IFI-54K) (P54) | Cytoplasm | ||
| Copper-transporting ATPase 1 (EC 3.6.3.54) (Copper pump 1) (Menkes disease-associated protein) | progressive muscular atrophy spinal muscular atrophy X-linked hereditary ataxia ... multiple system atrophy | Golgi apparatus, trans-Golgi network membrane | |
| Clathrin light chain A (Lca) | Cytoplasmic vesicle membrane | ||
| 3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (17-beta-hydroxysteroid dehydrogenase 10) (17-beta-HSD 10) (EC 1.1.1.51) (2-methyl-3-hydroxybutyryl-CoA dehydrogenase) (MHBD) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (3-hydroxyacyl-CoA dehydrogenase type II) (Endoplasmic reticulum-associated amyloid beta-peptide-binding protein) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Short chain dehydrogenase/reductase family 5C member 1) (Short-chain type dehydrogenase/reductase XH98G2) (Type II HADH) | Mitochondrion | ||
| Non-structural maintenance of chromosomes element 4 homolog A (NS4EA) (Non-SMC element 4 homolog A) | Nucleus | ||
| Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT) (EC 2.1.1.77) (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl/D-aspartyl methyltransferase) (Protein-beta-aspartate methyltransferase) | Cytoplasm. | ||
| Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit) | Nucleus | ||
| DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102) | Nucleus. | ||
| Eukaryotic translation initiation factor 3 subunit C-like protein | Cytoplasm | ||
| Riboflavin kinase (EC 2.7.1.26) (ATP:riboflavin 5'-phosphotransferase) (Flavokinase) | Cytoplasm | ||
| Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107) | Nucleus membrane | ||
| 28S ribosomal protein S27, mitochondrial (MRP-S27) (S27mt) (Mitochondrial ribosomal protein S27) (Mitochondrial small ribosomal subunit protein mS27) | Cytoplasm | ||
| Protein ABHD16A (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 16A) (Abhydrolase domain-containing protein 16A) (HLA-B-associated transcript 5) (Protein G5) | Membrane | ||
| Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa) | autosomal dominant cerebellar ataxia | Cytoplasm, P-body | |
| Prostaglandin F2-alpha receptor (PGF receptor) (PGF2-alpha receptor) (Prostanoid FP receptor) | Cell membrane | ||
| Importin subunit alpha-3 (Importin alpha Q1) (Qip1) (Karyopherin subunit alpha-4) | Cytoplasm | ||
| Cell cycle checkpoint protein RAD1 (hRAD1) (EC 3.1.11.2) (DNA repair exonuclease rad1 homolog) (Rad1-like DNA damage checkpoint protein) | Nucleus | ||
| ATP-dependent RNA helicase A (EC 3.6.4.13) (DEAH box protein 9) (DExH-box helicase 9) (Leukophysin) (LKP) (Nuclear DNA helicase II) (NDH II) (RNA helicase A) | Nucleus | ||
| Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein) | Cytoplasm | ||
| Intraflagellar transport protein 122 homolog (WD repeat-containing protein 10) (WD repeat-containing protein 140) | Cytoplasm | ||
| Mitotic interactor and substrate of PLK1 (Mitotic spindle positioning protein) | |||
| Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha) | autosomal recessive cerebellar ataxia | ||
| Peptidyl-prolyl cis-trans isomerase G (PPIase G) (Peptidyl-prolyl isomerase G) (EC 5.2.1.8) (CASP10) (Clk-associating RS-cyclophilin) (CARS-Cyp) (CARS-cyclophilin) (SR-cyclophilin) (SR-cyp) (SRcyp) (Cyclophilin G) (Rotamase G) | Nucleus matrix | ||
| NSFL1 cofactor p47 (UBX domain-containing protein 2C) (p97 cofactor p47) | Nucleus | ||
| DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8) | Parkinson disease Lewy body dementia | Early endosome | |
| RING finger protein 166 | |||
| Protein salvador homolog 1 (45 kDa WW domain protein) (hWW45) | Nucleus | ||
| NPC intracellular cholesterol transporter 2 (Epididymal secretory protein E1) (Human epididymis-specific protein 1) (He1) (Niemann-Pick disease type C2 protein) | Pick disease | Secreted | |
| Calcium-binding mitochondrial carrier protein SCaMC-3 (Mitochondrial ATP-Mg/Pi carrier protein 2) (Mitochondrial Ca(2+)-dependent solute carrier protein 2) (Small calcium-binding mitochondrial carrier protein 3) (Solute carrier family 25 member 23) | Mitochondrion inner membrane | ||
| Prolyl 3-hydroxylase OGFOD1 (EC 1.14.11.-) (2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1) (Termination and polyadenylation 1 homolog) (uS12 prolyl 3-hydroxylase) | |||
| Pre-mRNA-splicing factor SYF1 (Protein HCNP) (XPA-binding protein 2) | Nucleus | ||
| DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog) | Mitochondrion matrix | ||
| Myb-binding protein 1A | Cytoplasm | ||
| HBS1-like protein (ERFS) | |||
| 28S ribosomal protein S18c, mitochondrial (MRP-S18-c) (Mrps18-c) (S18mt-c) (28S ribosomal protein S18-1, mitochondrial) (MRP-S18-1) (Mitochondrial small ribosomal subunit protein bS18c) (Mitochondrial small ribosomal subunit protein bS18m) | Mitochondrion | ||
| Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3) | Nucleus | ||
| Copine-1 (Chromobindin 17) (Copine I) | Nucleus | ||
| Protein Hook homolog 2 (h-hook2) (hHK2) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Zinc finger and SCAN domain-containing protein 18 (Zinc finger protein 447) | Nucleus | ||
| Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2) | Cytoplasm | ||
| AN1-type zinc finger protein 2A | Cytoplasm | ||
| NADH-ubiquinone oxidoreductase chain 1 (EC 7.1.1.2) (NADH dehydrogenase subunit 1) | Alzheimer disease | Mitochondrion inner membrane | |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17) | Sarcoplasmic reticulum membrane | ||
| Aftiphilin | Cytoplasm | ||
| Protein transport protein Sec23A (hSec23A) (SEC23-related protein A) | Cytoplasmic vesicle, COPII-coated vesicle membrane | ||
| Hypermethylated in cancer 2 protein (Hic-2) (HIC1-related gene on chromosome 22 protein) (Hic-3) (Zinc finger and BTB domain-containing protein 30) | Nucleus. | ||
| Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (BRG1-associated factor 45D) (BAF45D) (D4, zinc and double PHD fingers family 2) (Protein requiem) | Nucleus | ||
| Pre-mRNA-processing factor 39 (PRP39 homolog) | Nucleus | ||
| Speckle-type POZ protein (HIB homolog 1) (Roadkill homolog 1) | Nucleus | ||
| WD repeat-containing protein 20 (Protein DMR) | |||
| Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) | Nucleus | ||
| Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X) | Cytoplasm | ||
| Beta-actin-like protein 2 (Kappa-actin) | Cytoplasm, cytoskeleton | ||
| Oxidation resistance protein 1 | Mitochondrion | ||
| Coenzyme Q-binding protein COQ10 homolog A, mitochondrial | Mitochondrion inner membrane | ||
| Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34) (Myeloid differentiation primary response protein MyD116 homolog) | Endoplasmic reticulum membrane | ||
| YTH domain-containing family protein 2 (CLL-associated antigen KW-14) (High-glucose-regulated protein 8) (Renal carcinoma antigen NY-REN-2) | Cytoplasm, cytosol | ||
| Acetolactate synthase-like protein (EC 2.2.1.-) (IlvB-like protein) | Membrane | ||
| Sperm-associated antigen 8 (HSD-1) (Sperm membrane protein 1) (SMP-1) (Sperm membrane protein BS-84) | Cytoplasm | ||
| Plasma alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase 2) (Alpha-L-fucosidase 2) | Secreted | ||
| Aldehyde dehydrogenase X, mitochondrial (EC 1.2.1.3) (Aldehyde dehydrogenase 5) (Aldehyde dehydrogenase family 1 member B1) | Mitochondrion matrix. | ||
| Calsyntenin-3 (Alcadein-beta) (Alc-beta) | Cell membrane | ||
| 28S ribosomal protein S11, mitochondrial (MRP-S11) (S11mt) (Cervical cancer proto-oncogene 2 protein) (HCC-2) (Mitochondrial small ribosomal subunit protein uS11m) | Mitochondrion | ||
| NF-kappa-B-repressing factor (NFkB-repressing factor) (Protein ITBA4) (Transcription factor NRF) | Nucleus, nucleolus | ||
| Protein S100-B (S-100 protein beta chain) (S-100 protein subunit beta) (S100 calcium-binding protein B) | Cytoplasm | ||
| Lipopolysaccharide-responsive and beige-like anchor protein (Beige-like protein) (CDC4-like protein) | Cell membrane | ||
| PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4) | Nucleus | ||
| Protein BUD31 homolog (Protein EDG-2) (Protein G10 homolog) | Nucleus | ||
| GPN-loop GTPase 1 (EC 3.6.5.-) (MBD2-interacting protein) (MBDin) (RNAPII-associated protein 4) (XPA-binding protein 1) | Cytoplasm | ||
| Glutathione S-transferase P (EC 2.5.1.18) (GST class-pi) (GSTP1-1) | Cytoplasm | ||
| 60S ribosomal protein L27 (Large ribosomal subunit protein eL27) | Cytoplasm, cytosol | ||
| Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Stimulator of Fe transport) (SFT) (UBC4/5 homolog) (UbcH5) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1) | Cytoplasm | ||
| Coiled-coil domain-containing protein 22 | autism spectrum disorder | Endosome | |
| Glucose-6-phosphate 1-dehydrogenase (G6PD) (EC 1.1.1.49) | |||
| Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain) | spastic ataxia | Cytoplasm, cytoskeleton. | |
| Aldehyde dehydrogenase family 3 member B1 (EC 1.2.1.5) (Aldehyde dehydrogenase 7) | Cell membrane | ||
| Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2) | Cytoplasm. | ||
| Nucleosome assembly protein 1-like 1 (NAP-1-related protein) (hNRP) | Nucleus | ||
| ATP-dependent RNA helicase DDX50 (EC 3.6.4.13) (DEAD box protein 50) (Gu-beta) (Nucleolar protein Gu2) | Nucleus, nucleolus | ||
| Growth arrest-specific protein 7 (GAS-7) | Cytoplasm | ||
| Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit) (Ribophorin I) (RPN-I) (Ribophorin-1) | Endoplasmic reticulum | ||
| U2 snRNP-associated SURP motif-containing protein (140 kDa Ser/Arg-rich domain protein) (U2-associated protein SR140) | Nucleus | ||
| 60S ribosomal protein L36 (Large ribosomal subunit protein eL36) | Cytoplasm, cytosol | ||
| Beta-centractin (Actin-related protein 1B) (ARP1B) | Cytoplasm, cytoskeleton | ||
| Peroxiredoxin-5, mitochondrial (EC 1.11.1.15) (Alu corepressor 1) (Antioxidant enzyme B166) (AOEB166) (Liver tissue 2D-page spot 71B) (PLP) (Peroxiredoxin V) (Prx-V) (Peroxisomal antioxidant enzyme) (TPx type VI) (Thioredoxin peroxidase PMP20) | Isoform Mitochondrial: Mitochondrion | ||
| 14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed] | Cytoplasm | ||
| 60S ribosomal protein L13 (Breast basic conserved protein 1) (Large ribosomal subunit protein eL13) | |||
| U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) | Nucleus | ||
| Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (Lysine acetyltransferase 5) (cPLA(2)-interacting protein) | Nucleus | ||
| Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744) | Cytoplasm | ||
| Death domain-associated protein 6 (Daxx) (hDaxx) (ETS1-associated protein 1) (EAP1) (Fas death domain-associated protein) | Cytoplasm | ||
| Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 2) (Glutamine:fructose-6-phosphate amidotransferase 2) (GFAT 2) (GFAT2) (Hexosephosphate aminotransferase 2) | |||
| Mimecan (Osteoglycin) (Osteoinductive factor) (OIF) | Secreted, extracellular space, extracellular matrix | ||
| SH3 domain-binding protein 1 | Cell projection | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (Complex I subunit B13) (Complex I-13kD-B) (CI-13kD-B) (NADH-ubiquinone oxidoreductase 13 kDa-B subunit) | Mitochondrion inner membrane | ||
| Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2) | autosomal recessive cerebellar ataxia | Cytoplasm, cytoskeleton, cilium basal body | |
| 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (AKB ligase) (EC 2.3.1.29) (Aminoacetone synthase) (Glycine acetyltransferase) | Mitochondrion | ||
| 26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2) | |||
| Mitochondrial import inner membrane translocase subunit TIM50 | Mitochondrion inner membrane | ||
| Zinc finger imprinted 2 (Zinc finger protein 656) | Nucleus | ||
| Transmembrane 4 L6 family member 19 (Osteoclast maturation-associated gene 4 protein) (Tetraspan membrane protein OCTM4) | Membrane | ||
| Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B) | |||
| Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1) [Cleaved into: Dynamin-like 120 kDa protein, form S1] | Mitochondrion inner membrane | ||
| Apoptosis-inducing factor 1, mitochondrial (EC 1.1.1.-) (Programmed cell death protein 8) | |||
| DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1) | Cytoplasm | ||
| Translocon-associated protein subunit alpha (TRAP-alpha) (Signal sequence receptor subunit alpha) (SSR-alpha) | Endoplasmic reticulum membrane | ||
| 3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (YTH domain-containing protein 2) (hYTHDC2) | Cytoplasm | ||
| GA-binding protein subunit beta-2 (GABP subunit beta-2) (GABPB-2) | Nucleus | ||
| Guanine nucleotide-binding protein-like 3 (E2-induced gene 3 protein) (Novel nucleolar protein 47) (NNP47) (Nucleolar GTP-binding protein 3) (Nucleostemin) | Nucleus | ||
| Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) | |||
| C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Cleaved into: C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed] [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)] | Cytoplasm. | ||
| Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit) | Cytoplasm | ||
| Achaete-scute homolog 4 (ASH-4) (hASH4) (Achaete-scute-like protein 4) (Class A basic helix-loop-helix protein 44) (bHLHa44) | Nucleus | ||
| Keratin-associated protein 8-1 (High glycine-tyrosine keratin-associated protein 8.1) | |||
| Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3-II) (Keratin-33B) (K33B) | |||
| 60 kDa heat shock protein, mitochondrial (EC 3.6.4.9) (60 kDa chaperonin) (Chaperonin 60) (CPN60) (Heat shock protein 60) (HSP-60) (Hsp60) (HuCHA60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) | Mitochondrion matrix. | ||
| Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP C-like-1) (hnRNP core protein C-like 1) | Nucleus | ||
| Host cell factor 1 (HCF) (HCF-1) (C1 factor) (CFF) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6] | Cytoplasm | ||
| Apolipoprotein C-II (Apo-CII) (ApoC-II) (Apolipoprotein C2) [Cleaved into: Proapolipoprotein C-II (ProapoC-II)] | Secreted | ||
| Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Acyl-CoA thioesterase 7) (Brain acyl-CoA hydrolase) (BACH) (CTE-IIa) (CTE-II) (Long chain acyl-CoA thioester hydrolase) | Isoform 4: Cytoplasm. | ||
| COMM domain-containing protein 8 | Cytoplasm | ||
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 1.6.99.3) (EC 7.1.1.2) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit) | Parkinson disease | Mitochondrion inner membrane | |
| PRELI domain-containing protein 1, mitochondrial (25 kDa protein of relevant evolutionary and lymphoid interest) (Px19-like protein) | Mitochondrion | ||
| UBX domain-containing protein 1 (SAPK substrate protein 1) (UBA/UBX 33.3 kDa protein) | Cytoplasm | ||
| Kell blood group glycoprotein (EC 3.4.24.-) (CD antigen CD238) | |||
| Inactive caspase-12 (CASP-12) | |||
| Far upstream element-binding protein 1 (FBP) (FUSE-binding protein 1) (DNA helicase V) (hDH V) | Nucleus | ||
| Keratin-associated protein 19-5 | |||
| Visual system homeobox 2 (Ceh-10 homeodomain-containing homolog) (Homeobox protein CHX10) | Nucleus. | ||
| Interleukin enhancer-binding factor 2 (Nuclear factor of activated T-cells 45 kDa) | |||
| 40S ribosomal protein S6 (Phosphoprotein NP33) (Small ribosomal subunit protein eS6) | |||
| Cyclin-L1 (Cyclin-L) | Nucleus speckle | ||
| 60S ribosomal protein L23a (Large ribosomal subunit protein uL23) | |||
| Microtubule-associated protein 1B (MAP-1B) [Cleaved into: MAP1B heavy chain; MAP1 light chain LC1] | Cytoplasm, cytoskeleton | ||
| Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B) | Nucleus, nucleolus | ||
| Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS) | Cytoplasm | ||
| Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1) | Cytoplasm | ||
| Repressor of RNA polymerase III transcription MAF1 homolog | Nucleus | ||
| 60S ribosomal protein L35a (Cell growth-inhibiting gene 33 protein) (Large ribosomal subunit protein eL33) | |||
| Zinc finger protein 670 | Nucleus | ||
| Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (Keratin-31) (K31) | |||
| D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37) | |||
| Transmembrane protein 165 (Transmembrane protein PT27) (Transmembrane protein TPARL) | Golgi apparatus membrane | ||
| Sorting nexin-9 (SH3 and PX domain-containing protein 1) (Protein SDP1) (SH3 and PX domain-containing protein 3A) | |||
| Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X) | Cytoplasm | ||
| Ribonuclease P protein subunit p25 (RNase P protein subunit p25) (EC 3.1.26.5) | Nucleus | ||
| Mannose-1-phosphate guanyltransferase alpha (GDP-mannose pyrophosphorylase A) (GMPP-alpha) (GTP-mannose-1-phosphate guanylyltransferase alpha) | Cytoplasm | ||
| DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (DNA-directed RNA polymerase II 23 kDa polypeptide) (DNA-directed RNA polymerase II subunit E) (RPB5 homolog) (XAP4) | Nucleus | ||
| Interleukin-12 receptor subunit beta-1 (IL-12 receptor subunit beta-1) (IL-12R subunit beta-1) (IL-12R-beta-1) (IL-12RB1) (IL-12 receptor beta component) (CD antigen CD212) | Membrane | ||
| Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (55 kDa nuclear protein) (DNA-binding p52/p100 complex, 52 kDa subunit) (NMT55) (p54(nrb)) (p54nrb) | |||
| Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1) | Nucleus | ||
| Vacuolar protein sorting-associated protein 54 (Hepatocellular carcinoma protein 8) (Tumor antigen HOM-HCC-8) (Tumor antigen SLP-8p) | Golgi apparatus, trans-Golgi network | ||
| Interleukin-17F (IL-17F) (Cytokine ML-1) | Secreted. | ||
| 60S ribosomal protein L35 (Large ribosomal subunit protein uL29) | |||
| Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PP2A subunit B isoform B55-beta) (PP2A subunit B isoform PR55-beta) (PP2A subunit B isoform R2-beta) (PP2A subunit B isoform beta) | autosomal dominant cerebellar ataxia | Isoform 1: Cytoplasm | |
| DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6) | Mitochondrion | ||
| Protein SCO2 homolog, mitochondrial | Mitochondrion inner membrane | ||
| ATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) (PFK-P) (EC 2.7.1.11) (6-phosphofructokinase type C) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphohexokinase) | Cytoplasm | ||
| Heterogeneous nuclear ribonucleoprotein R (hnRNP R) | Nucleus | ||
| U2 small nuclear ribonucleoprotein A' (U2 snRNP A') | Nucleus | ||
| Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17) | Cytoplasmic vesicle membrane | ||
| Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcH9) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3) | Nucleus | ||
| AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L) | pontocerebellar hypoplasia | ||
| Tyrosine--tRNA ligase, mitochondrial (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) | Mitochondrion matrix | ||
| Cold shock domain-containing protein E1 (N-ras upstream gene protein) (Protein UNR) | Cytoplasm. | ||
| Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220) | Nucleus speckle | ||
| Ligand-dependent nuclear receptor corepressor-like protein (LCoR-like protein) | Nucleus | ||
| CTP synthase 1 (EC 6.3.4.2) (CTP synthetase 1) (UTP--ammonia ligase 1) | |||
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 3.6.3.8) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase) | Endoplasmic reticulum membrane | ||
| Ameloblastin | Secreted, extracellular space, extracellular matrix. | ||
| THAP domain-containing protein 11 | Nucleus | ||
| 40S ribosomal protein S24 (Small ribosomal subunit protein eS24) | |||
| Cancer/testis antigen 1 (Autoimmunogenic cancer/testis antigen NY-ESO-1) (Cancer/testis antigen 6.1) (CT6.1) (L antigen family member 2) (LAGE-2) | Cytoplasm | ||
| 40S ribosomal protein S15 (RIG protein) (Small ribosomal subunit protein uS19) | |||
| Serine/threonine-protein phosphatase CPPED1 (EC 3.1.3.16) (Calcineurin-like phosphoesterase domain-containing protein 1) (Complete S-transactivated protein 1) | Cytoplasm | ||
| O-phosphoseryl-tRNA(Sec) selenium transferase (EC 2.9.1.2) (Liver-pancreas antigen) (LP) (SLA-p35) (SLA/LP autoantigen) (Selenocysteine synthase) (Sec synthase) (Selenocysteinyl-tRNA(Sec) synthase) (Sep-tRNA:Sec-tRNA synthase) (SepSecS) (Soluble liver antigen) (SLA) (UGA suppressor tRNA-associated protein) (tRNA(Ser/Sec)-associated antigenic protein) | pontocerebellar hypoplasia | Cytoplasm | |
| Acetyl-CoA acetyltransferase, mitochondrial (EC 2.3.1.9) (Acetoacetyl-CoA thiolase) (T2) | Mitochondrion. | ||
| WD and tetratricopeptide repeats protein 1 | |||
| Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP) | multiple system atrophy | Isoform 1: Cytoplasm | |
| Glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase) (GlnRS) | Cytoplasm, cytosol | ||
| Prohibitin | Mitochondrion inner membrane | ||
| Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75) | Nucleus | ||
| Homer protein homolog 2 (Homer-2) (Cupidin) | Cytoplasm | ||
| Mitochondrial inner membrane protease ATP23 homolog (EC 3.4.24.-) (Ku70-binding protein 3) (XRCC6-binding protein 1) | |||
| Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17) | Nucleus | ||
| snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (Proximal sequence element-binding transcription factor subunit gamma) (PSE-binding factor subunit gamma) (PTF subunit gamma) (Small nuclear RNA-activating complex polypeptide 1) (snRNA-activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit) | Nucleus. | ||
| Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2) | |||
| Exosome complex exonuclease RRP44 (EC 3.1.13.-) (EC 3.1.26.-) (Protein DIS3 homolog) (Ribosomal RNA-processing protein 44) | Cytoplasm | ||
| Eukaryotic translation initiation factor 2D (eIF2d) (Hepatocellular carcinoma-associated antigen 56) (Ligatin) | Cytoplasm | ||
| Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) | Mitochondrion | ||
| UBX domain-containing protein 7 | Nucleus | ||
| 60S ribosomal protein L12 (Large ribosomal subunit protein uL11) | |||
| CST complex subunit CTC1 (Conserved telomere maintenance component 1) (HBV DNAPTP1-transactivated protein B) | Nucleus | ||
| Nuclease-sensitive element-binding protein 1 (CCAAT-binding transcription factor I subunit A) (CBF-A) (DNA-binding protein B) (DBPB) (Enhancer factor I subunit A) (EFI-A) (Y-box transcription factor) (Y-box-binding protein 1) (YB-1) | Cytoplasm | ||
| 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112) | |||
| Kelch-like protein 26 | |||
| Nuclear receptor coactivator 3 (NCoA-3) (EC 2.3.1.48) (ACTR) (Amplified in breast cancer 1 protein) (AIB-1) (CBP-interacting protein) (pCIP) (Class E basic helix-loop-helix protein 42) (bHLHe42) (Receptor-associated coactivator 3) (RAC-3) (Steroid receptor coactivator protein 3) (SRC-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) | |||
| Target of EGR1 protein 1 | pontocerebellar hypoplasia | Nucleus, nucleolus | |
| Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHE1-B) (EC 1.2.4.1) | Mitochondrion matrix. | ||
| Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (Tat-interacting protein of 110 kDa) (Tip110) (p110 nuclear RNA-binding protein) | Nucleus, nucleoplasm | ||
| Cadherin-17 (Intestinal peptide-associated transporter HPT-1) (Liver-intestine cadherin) (LI-cadherin) | Cell membrane | ||
| 60S ribosomal protein L5 (Large ribosomal subunit protein uL18) | Cytoplasm | ||
| Ubiquitin-conjugating enzyme E2 E1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme E1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme E1) (UbcH6) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1) | Nucleus | ||
| Pentatricopeptide repeat domain-containing protein 3, mitochondrial (28S ribosomal protein S39, mitochondrial) (MRP-S39) (Mitochondrial small ribosomal subunit protein mS39) (Transformation-related gene 15 protein) (TRG-15) | Mitochondrion | ||
| 39S ribosomal protein L4, mitochondrial (L4mt) (MRP-L4) (Mitochondrial large ribosomal subunit protein uL4m) | Mitochondrion | ||
| E3 ubiquitin-protein ligase RNF14 (EC 2.3.2.31) (Androgen receptor-associated protein 54) (HFB30) (RING finger protein 14) (Triad2 protein) | Cytoplasm | ||
| 39S ribosomal protein L1, mitochondrial (L1mt) (MRP-L1) (Mitochondrial large ribosomal subunit protein uL1m) | Mitochondrion | ||
| Pituitary homeobox 2 (ALL1-responsive protein ARP1) (Homeobox protein PITX2) (Paired-like homeodomain transcription factor 2) (RIEG bicoid-related homeobox transcription factor) (Solurshin) | Nucleus. | ||
| Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I) | lateral sclerosis amyotrophic lateral sclerosis | Cytoplasm, cytoskeleton. | |
| STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39) | Cytoplasm | ||
| Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2) | Cytoplasm, cytoskeleton | ||
| Adenomatous polyposis coli protein 2 (Adenomatous polyposis coli protein-like) (APC-like) | autism spectrum disorder | Cytoplasm, cytoskeleton | |
| ATP-dependent RNA helicase DDX24 (EC 3.6.4.13) (DEAD box protein 24) | |||
| TAR DNA-binding protein 43 (TDP-43) | lateral sclerosis amyotrophic lateral sclerosis | Nucleus | |
| Protein transport protein Sec24C (SEC24-related protein C) | Cytoplasmic vesicle, COPII-coated vesicle membrane | ||
| Plakophilin-2 | Nucleus | ||
| Ankyrin repeat family A protein 2 (RFXANK-like protein 2) | Cytoplasm, cytoskeleton | ||
| 60S ribosomal protein L26-like 1 (Large ribosomal subunit protein uL24-like 1) | |||
| Y-box-binding protein 3 (Cold shock domain-containing protein A) (DNA-binding protein A) (Single-strand DNA-binding protein NF-GMB) | Cytoplasm | ||
| Basigin (5F7) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (Leukocyte activation antigen M6) (OK blood group antigen) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (CD antigen CD147) | Cell membrane | ||
| Transcriptional regulator ERG (Transforming protein ERG) | Nucleus | ||
| Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2) | |||
| Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI) | Cytoplasm | ||
| WD repeat-containing protein 35 (Intraflagellar transport protein 121 homolog) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Protein phosphatase 1 regulatory subunit 21 (Coiled-coil domain-containing protein 128) (KLRAQ motif-containing protein 1) | |||
| Mitochondrial import inner membrane translocase subunit Tim13 | Mitochondrion inner membrane | ||
| MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled-coil domain protein 1) | Nucleus | ||
| Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, mitochondrial) (MRP-S38) (Mitochondrial small ribosomal subunit protein mS38) | Mitochondrion | ||
| 39S ribosomal protein L50, mitochondrial (L50mt) (MRP-L50) (Mitochondrial large ribosomal subunit protein mL50) | Mitochondrion | ||
| Xaa-Pro dipeptidase (X-Pro dipeptidase) (EC 3.4.13.9) (Imidodipeptidase) (Peptidase D) (Proline dipeptidase) (Prolidase) | |||
| Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase (EC 2.1.1.-) (Nucleolar protein 1) (Nucleolar protein 2 homolog) (Proliferating-cell nucleolar antigen p120) (Proliferation-associated nucleolar protein p120) | Nucleus, nucleolus | ||
| Protein LSM12 homolog | |||
| Melanophilin (Exophilin-3) (Slp homolog lacking C2 domains a) (SlaC2-a) (Synaptotagmin-like protein 2a) | Cytoplasm. | ||
| V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar ATPase isoform VA68) (Vacuolar proton pump subunit alpha) | Cytoplasm | ||
| Cytochrome P450 4V2 (EC 1.14.14.-) (Docosahexaenoic acid omega-hydroxylase CYP4V2) (EC 1.14.14.79) | multiple sclerosis | Endoplasmic reticulum membrane | |
| Eukaryotic translation initiation factor 4E-binding protein 3 (4E-BP3) (eIF4E-binding protein 3) | |||
| DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2) | Membrane | ||
| Fragile X mental retardation syndrome-related protein 1 (hFXR1p) | Cytoplasm | ||
| Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1) | |||
| Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (STAF130) (Spliceosome-associated protein 130) (SAP 130) | Nucleus | ||
| Partitioning defective 3 homolog B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 19 protein) (PAR3-beta) (Partitioning defective 3-like protein) (PAR3-L protein) | lateral sclerosis multiple sclerosis | ||
| TANK-binding kinase 1-binding protein 1 (TBK1-binding protein 1) | |||
| Matrin-3 | lateral sclerosis amyotrophic lateral sclerosis | Nucleus matrix. | |
| 40S ribosomal protein S28 (Small ribosomal subunit protein eS28) | Cytoplasm, cytosol | ||
| Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog B2-1) | Cell membrane | ||
| Protein argonaute-1 (Argonaute1) (hAgo1) (Argonaute RISC catalytic component 1) (Eukaryotic translation initiation factor 2C 1) (eIF-2C 1) (eIF2C 1) (Putative RNA-binding protein Q99) | Cytoplasm, P-body | ||
| DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPA39) (RPC40) | Nucleus | ||
| Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262) | Membrane | ||
| Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)] | Lysosome. | ||
| Neutral amino acid transporter B(0) (ATB(0)) (Baboon M7 virus receptor) (RD114/simian type D retrovirus receptor) (Sodium-dependent neutral amino acid transporter type 2) (Solute carrier family 1 member 5) | Cell membrane | ||
| Protein Daple (Coiled-coil domain-containing protein 88C) (Dvl-associating protein with a high frequency of leucine residues) (hDaple) (Hook-related protein 2) (HkRP2) | autosomal dominant cerebellar ataxia | Cytoplasm | |
| Neurexophilin-3 | Secreted | ||
| Glycogen phosphorylase, liver form (EC 2.4.1.1) | |||
| Pleckstrin homology-like domain family A member 3 (TDAG51/Ipl homolog 1) | Cytoplasm | ||
| Protein FAM83G (Protein associated with SMAD1) | Cytoplasm, cytosol | ||
| WD repeat-containing protein 82 (Protein TMEM113) (Swd2) | Nucleus | ||
| Induced myeloid leukemia cell differentiation protein Mcl-1 (Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT) | Membrane | ||
| Protein MCM10 homolog (HsMCM10) | Nucleus | ||
| Ubiquitin thioesterase otulin (EC 3.4.19.12) (Deubiquitinating enzyme otulin) (OTU domain-containing deubiquitinase with linear linkage specificity) (Ubiquitin thioesterase Gumby) | Cytoplasm | ||
| 60S ribosomal protein L26 (Large ribosomal subunit protein uL24) | |||
| Cystatin-SN (Cystain-SA-I) (Cystatin-1) (Salivary cystatin-SA-1) | Secreted | ||
| Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST 13-13) (GST class-kappa) (GSTK1-1) (hGSTK1) (Glutathione S-transferase subunit 13) | Peroxisome | ||
| Cysteine and tyrosine-rich protein 1 (Proline-rich domain-containing protein) | Membrane | ||
| Homeobox protein Hox-A9 (Homeobox protein Hox-1G) | Nucleus. | ||
| Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1) | Cytoplasm | ||
| Protein SCAF11 (CTD-associated SR protein 11) (Renal carcinoma antigen NY-REN-40) (SC35-interacting protein 1) (SR-related and CTD-associated factor 11) (SRSF2-interacting protein) (Serine/arginine-rich splicing factor 2-interacting protein) (Splicing factor, arginine/serine-rich 2-interacting protein) (Splicing regulatory protein 129) (SRrp129) | Nucleus | ||
| Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42) | Chromosome, centromere, kinetochore | ||
| Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A) | Nucleus | ||
| Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53) | |||
| Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1) | |||
| Zinc finger protein 511 | Nucleus | ||
| Histone H2A type 1-B/E (Histone H2A.2) (Histone H2A/a) (Histone H2A/m) | Nucleus | ||
| Calicin | |||
| TSC22 domain family protein 1 (Cerebral protein 2) (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein) | Cytoplasm | ||
| Tubulin alpha-1B chain (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain] | Cytoplasm, cytoskeleton. | ||
| IST1 homolog (hIST1) (Putative MAPK-activating protein PM28) | Cytoplasmic vesicle | ||
| Abscission/NoCut checkpoint regulator (ANCHR) (MLL partner containing FYVE domain) (Zinc finger FYVE domain-containing protein 19) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3) | Cytoplasm | ||
| Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa] | Cytoplasm | ||
| Caspase recruitment domain-containing protein 19 (Bcl10-interacting CARD protein) (BinCARD) | Isoform 1: Nucleus | ||
| Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein) | spinal muscular atrophy | ||
| Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis) | Cytoplasm | ||
| Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (hGCN5) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) (STAF97) | Nucleus | ||
| APOBEC1 complementation factor (APOBEC1-stimulating protein) | Nucleus | ||
| Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) | Nucleus. | ||
| Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein) | Cytoplasm | ||
| Disabled homolog 2-interacting protein (DAB2 interaction protein) (DAB2-interacting protein) (ASK-interacting protein 1) (AIP-1) (DOC-2/DAB-2 interactive protein) | Cytoplasm | ||
| Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod) | Cytoplasm, cytoskeleton | ||
| 26S proteasome regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42) | Cytoplasm | ||
| Sideroflexin-1 (Tricarboxylate carrier protein) (TCC) | Mitochondrion membrane | ||
| Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4) | episodic ataxia | ||
| Histone H1.1 (Histone H1a) | Nucleus | ||
| DDB1- and CUL4-associated factor 6 (Androgen receptor complex-associated protein) (ARCAP) (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP) | Nucleus | ||
| Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase) | |||
| Copper homeostasis protein cutC homolog | Cytoplasm | ||
| Zinc finger protein 8 (Zinc finger protein HF.18) | Nucleus | ||
| Centrosomal protein of 76 kDa (Cep76) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Coiled-coil domain-containing protein 88B (Brain leucine zipper domain-containing protein) (Gipie) (Hook-related protein 3) (HkRP3) | Membrane | ||
| Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (Phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit) (Protein FOAP-2) (PtdIns-3-kinase p101) (p101-PI3K) | autosomal recessive cerebellar ataxia | Nucleus | |
| XIAP-associated factor 1 (BIRC4-binding protein) | |||
| Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)] | Dipeptidyl peptidase 4 soluble form: Secreted | ||
| Epidermal growth factor receptor kinase substrate 8 | Cytoplasm, cell cortex | ||
| Homeobox protein Hox-B2 (Homeobox protein Hox-2.8) (Homeobox protein Hox-2H) (K8) | Nucleus. | ||
| Guanine nucleotide-binding protein G(o) subunit alpha | Cell membrane | ||
| Homeobox protein Hox-B9 (Homeobox protein Hox-2.5) (Homeobox protein Hox-2E) | Nucleus. | ||
| Myb-related protein A (A-Myb) (Myb-like protein 1) | Nucleus | ||
| Transcriptional activator GLI3 (GLI3 form of 190 kDa) (GLI3-190) (GLI3 full-length protein) (GLI3FL) [Cleaved into: Transcriptional repressor GLI3R (GLI3 C-terminally truncated form) (GLI3 form of 83 kDa) (GLI3-83)] | |||
| E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23) | Cytoplasm | ||
| Transcription factor MafB (Maf-B) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) | Nucleus | ||
| Testis-expressed protein 11 | Chromosome | ||
| U3 small nucleolar RNA-associated protein 14 homolog C | Nucleus, nucleolus | ||
| Ras GTPase-activating-like protein IQGAP1 (p195) | Cell membrane | ||
| E3 ubiquitin-protein ligase NEDD4-like (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase NED4L) (NEDD4.2) (Nedd4-2) | Cytoplasm | ||
| Ras-related protein Rab-7a | Cytoplasmic vesicle, phagosome membrane | ||
| Solute carrier family 5 member 4 | Cell membrane | ||
| Syntaxin-4 (Renal carcinoma antigen NY-REN-31) | Cell membrane | ||
| Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b) | Cell membrane | ||
| Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17) | Endomembrane system | ||
| Centrosomal protein of 164 kDa (Cep164) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole | ||
| Protein phosphatase 1F (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase) (CaM-kinase phosphatase) (CaMKPase) (Partner of PIX 2) (Protein fem-2 homolog) (hFem-2) | |||
| Lipase member H (LIPH) (EC 3.1.1.-) (LPD lipase-related protein) (Membrane-associated phosphatidic acid-selective phospholipase A1-alpha) (mPA-PLA1 alpha) (Phospholipase A1 member B) | Secreted | ||
| CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CBF) (CCAAT-binding factor) | Nucleus. | ||
| Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1) | Nucleus | ||
| Cathepsin B (EC 3.4.22.1) (APP secretase) (APPS) (Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain] | Lysosome | ||
| Ribonuclease H2 subunit B (RNase H2 subunit B) (Aicardi-Goutieres syndrome 2 protein) (AGS2) (Deleted in lymphocytic leukemia 8) (Ribonuclease HI subunit B) | Nucleus | ||
| Transcription factor BTF3 (Nascent polypeptide-associated complex subunit beta) (NAC-beta) (RNA polymerase B transcription factor 3) | Cytoplasm | ||
| Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein) | Cytoplasm | ||
| Tau-tubulin kinase 2 (EC 2.7.11.1) | autosomal dominant cerebellar ataxia | Cell projection, cilium | |
| Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4) | Mitochondrion inner membrane | ||
| Nucleolar protein 11 | Nucleus, nucleolus | ||
| Syntaxin-8 | Membrane | ||
| Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein) (Protein related to CPSF subunits of 68 kDa) (RC-68) | Nucleus | ||
| Mitochondrial mRNA pseudouridine synthase RPUSD3 (EC 5.4.99.-) (RNA pseudouridylate synthase domain-containing protein 3) | Mitochondrion matrix | ||
| NHP2-like protein 1 (High mobility group-like nuclear protein 2 homolog 1) (OTK27) (SNU13 homolog) (hSNU13) (U4/U6.U5 small nuclear ribonucleoprotein SNU13) (U4/U6.U5 tri-snRNP 15.5 kDa protein) [Cleaved into: NHP2-like protein 1, N-terminally processed] | Nucleus | ||
| Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD) | Nucleus | ||
| Thyrotropin receptor (Thyroid-stimulating hormone receptor) (TSH-R) | Cell membrane | ||
| DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme) | autism spectrum disorder | Cytoplasm | |
| Pericentriolar material 1 protein (PCM-1) (hPCM-1) | Cytoplasm, cytoskeleton | ||
| Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1) | Nucleus matrix | ||
| Coiled-coil domain-containing protein 13 | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite | ||
| ATP-binding cassette sub-family F member 3 | |||
| Probable ATP-dependent RNA helicase DDX47 (EC 3.6.4.13) (DEAD box protein 47) | Nucleus, nucleolus | ||
| V-type proton ATPase subunit C 1 (V-ATPase subunit C 1) (Vacuolar proton pump subunit C 1) | |||
| Leukocyte surface antigen CD53 (Cell surface glycoprotein CD53) (Tetraspanin-25) (Tspan-25) (CD antigen CD53) | Cell membrane | ||
| Transducin beta-like protein 3 (WD repeat-containing protein SAZD) | Nucleus, nucleolus | ||
| Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-) | Mitochondrion | ||
| Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a) | Cytoplasm | ||
| Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2) | lateral sclerosis | ||
| Protein HEXIM2 (Hexamethylene bis-acetamide-inducible protein 2) | Nucleus | ||
| Ragulator complex protein LAMTOR3 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3) (MEK-binding partner 1) (Mp1) (Mitogen-activated protein kinase kinase 1-interacting protein 1) (Mitogen-activated protein kinase scaffold protein 1) | Late endosome membrane | ||
| Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) | Cytoplasm, cytosol | ||
| Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe) | Cytoplasm, cytosol | ||
| Histone deacetylase 11 (HD11) (EC 3.5.1.98) | |||
| Signal transducer and activator of transcription 6 (IL-4 Stat) | |||
| THAP domain-containing protein 7 | Nucleus | ||
| Tumor protein p73 (p53-like transcription factor) (p53-related protein) | Nucleus | ||
| Fibroblast growth factor 17 (FGF-17) | Secreted. | ||
| Thymosin beta-10 | Cytoplasm, cytoskeleton. | ||
| Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (CCT-alpha) (CTP:phosphocholine cytidylyltransferase A) (CCT A) (CT A) (Phosphorylcholine transferase A) | Cytoplasm, cytosol | ||
| ATP-dependent RNA helicase DDX39A (EC 3.6.4.13) (DEAD box protein 39) (Nuclear RNA helicase URH49) | Nucleus | ||
| Glycine--tRNA ligase (EC 3.6.1.17) (EC 6.1.1.14) (Diadenosine tetraphosphate synthetase) (AP-4-A synthetase) (Glycyl-tRNA synthetase) (GlyRS) | Cytoplasm | ||
| Uroplakin-1b (UP1b) (Tetraspanin-20) (Tspan-20) (Uroplakin Ib) (UPIb) | Membrane | ||
| Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form] | Cell membrane | ||
| Kallikrein-5 (EC 3.4.21.-) (Kallikrein-like protein 2) (KLK-L2) (Stratum corneum tryptic enzyme) | Secreted. | ||
| Ly6/PLAUR domain-containing protein 6 | Secreted | ||
| Lebercilin (Leber congenital amaurosis 5 protein) | Cytoplasm, cytoskeleton | ||
| Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (SNF7 homolog associated with Alix 1) (SNF7-2) (hSnf7-2) (Vacuolar protein sorting-associated protein 32-2) (Vps32-2) (hVps32-2) | Cytoplasm, cytosol | ||
| PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein) | Cytoplasm, perinuclear region | ||
| Interleukin-7 receptor subunit alpha (IL-7 receptor subunit alpha) (IL-7R subunit alpha) (IL-7R-alpha) (IL-7RA) (CDw127) (CD antigen CD127) | multiple sclerosis | Isoform 1: Cell membrane | |
| Tetraspanin-3 (Tspan-3) (Tetraspanin TM4-A) (Transmembrane 4 superfamily member 8) | Membrane | ||
| Reticulon-1 (Neuroendocrine-specific protein) | Endoplasmic reticulum membrane | ||
| Protein scribble homolog (Scribble) (hScrib) (Protein LAP4) | Cell membrane | ||
| Protein ecdysoneless homolog (Human suppressor of GCR two) (hSGT1) | Cytoplasm | ||
| Cell division cycle protein 123 homolog (Protein D123) (HT-1080) (PZ32) | Cytoplasm | ||
| DNA mismatch repair protein Msh2 (hMSH2) (MutS protein homolog 2) | Nucleus | ||
| Modulator of apoptosis 1 (MAP-1) (MAP1) (Paraneoplastic antigen Ma4) | |||
| PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein) | Cell junction, synapse, postsynaptic cell membrane, postsynaptic density | ||
| Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] | Isoform 1: Secreted, extracellular space, extracellular matrix | ||
| Protein jagged-2 (Jagged2) (hJ2) | Membrane | ||
| SAFB-like transcription modulator (Modulator of estrogen-induced transcription) | Nucleus | ||
| Calcium-binding protein 1 (CaBP1) (Calbrain) (Caldendrin) | Cytoplasm, cytoskeleton | ||
| General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma) | Nucleus. | ||
| Signal recognition particle 9 kDa protein (SRP9) | Cytoplasm. | ||
| Proprotein convertase subtilisin/kexin type 5 (EC 3.4.21.-) (Proprotein convertase 5) (PC5) (Proprotein convertase 6) (PC6) (hPC6) (Subtilisin/kexin-like protease PC5) | |||
| Secretoglobin family 2B member 2 (Secretoglobin-like protein) | Secreted | ||
| Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) | |||
| Cysteine-rich tail protein 1 | |||
| Pro-neuregulin-3, membrane-bound isoform (Pro-NRG3) [Cleaved into: Neuregulin-3 (NRG-3)] | Pro-neuregulin-3, membrane-bound isoform: Cell membrane | ||
| Amphoterin-induced protein 2 (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA) | Cell membrane | ||
| Deaminated glutathione amidase (dGSH amidase) (EC 3.5.1.128) (Nitrilase homolog 1) | Isoform 2: Mitochondrion | ||
| Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1) | Cell membrane | ||
| Ribosome-recycling factor, mitochondrial (RRF) (Ribosome-releasing factor, mitochondrial) | Mitochondrion | ||
| Cytosolic phospholipase A2 beta (cPLA2-beta) (EC 3.1.1.4) (Phospholipase A2 group IVB) | Cytoplasm, cytosol | ||
| Caspase recruitment domain-containing protein 6 | |||
| Ribonuclease inhibitor (Placental ribonuclease inhibitor) (Placental RNase inhibitor) (Ribonuclease/angiogenin inhibitor 1) (RAI) | Cytoplasm. | ||
| SEC23-interacting protein (p125) | Cytoplasmic vesicle, COPII-coated vesicle membrane | ||
| L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2) (Duranin) | autosomal recessive cerebellar ataxia | Mitochondrion | |
| REST corepressor 3 | Nucleus | ||
| DNA-binding death effector domain-containing protein 2 (DED-containing protein FLAME-3) (FADD-like anti-apoptotic molecule 3) | Nucleus, nucleolus | ||
| Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK) | Nucleus, nucleoplasm | ||
| Condensin complex subunit 2 (Barren homolog protein 1) (Chromosome-associated protein H) (hCAP-H) (Non-SMC condensin I complex subunit H) (XCAP-H homolog) | Nucleus | ||
| Pre-rRNA-processing protein TSR1 homolog | Nucleus, nucleolus | ||
| Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Actin-binding LIM protein 1 (abLIM-1) (Actin-binding LIM protein family member 1) (Actin-binding double zinc finger protein) (LIMAB1) (Limatin) | Cytoplasm | ||
| Nucleoside diphosphate-linked moiety X motif 19 (Nudix motif 19) (EC 3.6.1.-) | Peroxisome | ||
| T-cell surface glycoprotein CD5 (Lymphocyte antigen T1/Leu-1) (CD antigen CD5) | Cell membrane | ||
| Coiled-coil domain-containing protein 130 (9 kDa protein) | |||
| Wiskott-Aldrich syndrome protein family member 2 (WASP family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2) | Cytoplasm, cytoskeleton | ||
| Protein PIH1D3 (PIH1 domain-containing protein 3) (Sarcoma antigen NY-SAR-97) | Cytoplasm | ||
| Secretogranin-1 (Chromogranin-B) (CgB) (Secretogranin I) (SgI) [Cleaved into: PE-11; GAWK peptide; CCB peptide] | |||
| Tubulin-specific chaperone E (Tubulin-folding cofactor E) | progressive muscular atrophy | Cytoplasm | |
| Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor) | Endoplasmic reticulum membrane | ||
| Glutamate receptor 4 (GluR-4) (GluR4) (AMPA-selective glutamate receptor 4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (GluA4) | |||
| Transcription factor SOX-6 | Nucleus | ||
| Lysine-specific demethylase 5C (EC 1.14.11.-) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169) | Nucleus | ||
| Corticotropin-releasing factor-binding protein (CRF-BP) (CRF-binding protein) (Corticotropin-releasing hormone-binding protein) (CRH-BP) | Secreted. | ||
| Centromere protein H (CENP-H) (Interphase centromere complex protein 35) | |||
| Forkhead box protein P3 (Scurfin) [Cleaved into: Forkhead box protein P3, C-terminally processed; Forkhead box protein P3 41 kDa form] | Nucleus | ||
| Kinesin-like protein KIF2C (Kinesin-like protein 6) (Mitotic centromere-associated kinesin) (MCAK) | Cytoplasm, cytoskeleton | ||
| Optineurin (E3-14.7K-interacting protein) (FIP-2) (Huntingtin yeast partner L) (Huntingtin-interacting protein 7) (HIP-7) (Huntingtin-interacting protein L) (NEMO-related protein) (Optic neuropathy-inducing protein) (Transcription factor IIIA-interacting protein) (TFIIIA-IntP) | lateral sclerosis amyotrophic lateral sclerosis | Cytoplasm, perinuclear region | |
| Histone lysine demethylase PHF8 (EC 1.14.11.27) (PHD finger protein 8) | autism spectrum disorder | ||
| Membrane-bound transcription factor site-1 protease (EC 3.4.21.112) (Endopeptidase S1P) (Subtilisin/kexin-isozyme 1) (SKI-1) | Endoplasmic reticulum membrane | ||
| TATA box-binding protein-associated factor RNA polymerase I subunit D (RNA polymerase I-specific TBP-associated factor 41 kDa) (TAFI41) (TATA box-binding protein-associated factor 1D) (TBP-associated factor 1D) (Transcription initiation factor SL1/TIF-IB subunit D) | Nucleus | ||
| Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) | Nucleus | ||
| M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Uncharacterized protein C2orf50 | |||
| Trypsin-3 (EC 3.4.21.4) (Brain trypsinogen) (Mesotrypsin) (Mesotrypsinogen) (Serine protease 3) (Serine protease 4) (Trypsin III) (Trypsin IV) | Secreted | ||
| Histone chaperone ASF1A (Anti-silencing function protein 1 homolog A) (hAsf1) (hAsf1a) (CCG1-interacting factor A) (CIA) (hCIA) | Nucleus | ||
| Neuronal acetylcholine receptor subunit alpha-9 (Nicotinic acetylcholine receptor subunit alpha-9) (NACHR alpha-9) | Cell junction, synapse, postsynaptic cell membrane | ||
| HLA class II histocompatibility antigen, DR alpha chain (MHC class II antigen DRA) | |||
| General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein) | Cytoplasm, perinuclear region | ||
| Plexin-B1 (Semaphorin receptor SEP) | Isoform 1: Cell membrane | ||
| ERI1 exoribonuclease 3 (EC 3.1.-.-) (Prion interactor 1) (Prion protein-interacting protein) | |||
| Centromere protein C (CENP-C) (Centromere autoantigen C) (Centromere protein C 1) (CENP-C 1) (Interphase centromere complex protein 7) | Nucleus | ||
| Protein hinderin | |||
| ATP synthase subunit e, mitochondrial (ATPase subunit e) (ATP synthase membrane subunit e) [Cleaved into: ATP synthase subunit e, mitochondrial, N-terminally processed] | Mitochondrion | ||
| Cep170-like protein (CEP170 pseudogene 1) | |||
| C-C motif chemokine 28 (Mucosae-associated epithelial chemokine) (MEC) (Protein CCK1) (Small-inducible cytokine A28) | Secreted. | ||
| Proton channel OTOP3 (Otopetrin-3) | Cell membrane | ||
| Transmembrane 6 superfamily member 2 | Endoplasmic reticulum membrane | ||
| Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.8.27) (Sphingomyelin synthase 2) | |||
| Protein unc-93 homolog A (HmUnc-93A) (Unc-93A) | Cell membrane | ||
| Centrin-3 | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Ligand-dependent nuclear receptor-interacting factor 1 (HP1-binding protein enriched in inactive X chromosome protein 1) (HBiX1) (Receptor-interacting factor 1) | Chromosome | ||
| Oxidoreductase-like domain-containing protein 1 | |||
| [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKD-kinase) (BCKDHKIN) | autism spectrum disorder | Mitochondrion matrix | |
| Pituitary adenylate cyclase-activating polypeptide (PACAP) [Cleaved into: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)] | Secreted. | ||
| tRNA wybutosine-synthesizing protein 4 (tRNA yW-synthesizing protein 4) (EC 2.1.1.290) (EC 2.3.1.231) (Leucine carboxyl methyltransferase 2) (tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase) | |||
| Protein unc-119 homolog A (Retinal protein 4) (hRG4) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (GMP-PDE delta) (Protein p17) | Cytoplasm, cytosol | ||
| Dysbindin (Biogenesis of lysosome-related organelles complex 1 subunit 8) (BLOC-1 subunit 8) (Dysbindin-1) (Dystrobrevin-binding protein 1) (Hermansky-Pudlak syndrome 7 protein) (HPS7 protein) | Isoform 1: Cytoplasm | ||
| Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin-specific peptidase 54) | |||
| Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) | Nucleus | ||
| C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) (K5-5) (CD antigen CD194) | Cell membrane | ||
| Transcription factor 4 (TCF-4) (Class B basic helix-loop-helix protein 19) (bHLHb19) (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2) | Nucleus | ||
| Transmembrane protein 205 | Membrane | ||
| Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand) | Secreted | ||
| Leucine-rich repeat and fibronectin type-III domain-containing protein 3 (Synaptic adhesion-like molecule 4) | Cell membrane | ||
| Lysophosphatidic acid receptor 1 (LPA receptor 1) (LPA-1) (Lysophosphatidic acid receptor Edg-2) | Cell surface | ||
| Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein) | Nucleus | ||
| NudC domain-containing protein 2 | Chromosome, centromere, kinetochore | ||
| E3 ubiquitin-protein ligase RNF128 (EC 2.3.2.27) (Gene related to anergy in lymphocytes protein) (GRAIL) (RING finger protein 128) (RING-type E3 ubiquitin transferase RNF128) | Endomembrane system | ||
| Autophagy protein 5 (APG5-like) (Apoptosis-specific protein) | autosomal recessive cerebellar ataxia | Cytoplasm | |
| Tumor necrosis factor receptor superfamily member 14 (Herpes virus entry mediator A) (Herpesvirus entry mediator A) (HveA) (Tumor necrosis factor receptor-like 2) (TR2) (CD antigen CD270) | Membrane | ||
| Guanylate-binding protein 2 (EC 3.6.5.-) (GTP-binding protein 2) (GBP-2) (HuGBP-2) (Guanine nucleotide-binding protein 2) (Interferon-induced guanylate-binding protein 2) | Cytoplasm | ||
| Zinc fingers and homeoboxes protein 1 | Nucleus | ||
| Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response mediator protein 1) (CRMP-1) (Unc-33-like phosphoprotein 3) (ULIP-3) | Cytoplasm | ||
| Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (ThiFP1) (UFM1-activating enzyme) (Ubiquitin-activating enzyme E1 domain-containing protein 1) | autosomal recessive cerebellar ataxia | Cytoplasm | |
| Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase) (Dinucleosidetriphosphatase) (Fragile histidine triad protein) | autism spectrum disorder | Cytoplasm | |
| Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein) | Mitochondrion matrix | ||
| Mastermind-like protein 3 (Mam-3) | Nucleus speckle | ||
| Poly(rC)-binding protein 3 (Alpha-CP3) (PCBP3-overlapping transcript) (PCBP3-overlapping transcript 1) | Cytoplasm | ||
| Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (M2 antigen complex 70 kDa subunit) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2) | episodic ataxia | Mitochondrion matrix. | |
| Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (Lipoyl-containing pyruvate dehydrogenase complex component X) (proX) | Mitochondrion matrix. | ||
| Ankyrin repeat and SOCS box protein 15 (ASB-15) | |||
| Cysteine desulfurase, mitochondrial (EC 2.8.1.7) | Isoform Mitochondrial: Mitochondrion | ||
| Signal transducer and activator of transcription 5B | Cytoplasm | ||
| Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter) | Cell membrane | ||
| Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (p75 ICD) (CD antigen CD271) | Membrane | ||
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3) | Mitochondrion matrix. | ||
| Small EDRK-rich factor 2 (Gastric cancer-related protein VRG107) (Protein 4F5-related) (4F5rel) (h4F5rel) | spinal muscular atrophy | ||
| COMM domain-containing protein 2 | Cytoplasm | ||
| Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29) | Nucleus | ||
| G protein pathway suppressor 2 (GPS-2) | Nucleus | ||
| NGFI-A-binding protein 2 (EGR-1-binding protein 2) (Melanoma-associated delayed early response protein) (Protein MADER) | Nucleus | ||
| 60S ribosomal protein L29 (Cell surface heparin-binding protein HIP) (Large ribosomal subunit protein eL29) | |||
| Thioredoxin domain-containing protein 9 (ATP-binding protein associated with cell differentiation) (Protein 1-4) | Cytoplasm | ||
| Regulator of G-protein signaling 2 (RGS2) (Cell growth-inhibiting gene 31 protein) (G0/G1 switch regulatory protein 8) | Isoform 1: Cell membrane | ||
| Solute carrier family 2, facilitated glucose transporter member 5 (Fructose transporter) (Glucose transporter type 5, small intestine) (GLUT-5) | Apical cell membrane | ||
| Cleavage stimulation factor subunit 2 (CF-1 64 kDa subunit) (Cleavage stimulation factor 64 kDa subunit) (CSTF 64 kDa subunit) (CstF-64) | Nucleus | ||
| Protein boule-like | Cytoplasm | ||
| Zinc finger protein 219 | Nucleus | ||
| DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A) | Nucleus | ||
| Transmembrane protein 190 | Membrane | ||
| Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1) | Cytoplasm, cytosol | ||
| Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)] | |||
| Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a) | Nucleus | ||
| MICOS complex subunit MIC60 (Cell proliferation-inducing gene 4/52 protein) (Mitochondrial inner membrane protein) (Mitofilin) (p87/89) | Mitochondrion inner membrane | ||
| Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (CXXC-type zinc finger protein 7) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)] | Nucleus | ||
| Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G) (hMAF) | Nucleus | ||
| Protein Red (Cytokine IK) (IK factor) (Protein RER) | Nucleus | ||
| Transthyretin (ATTR) (Prealbumin) (TBPA) | Secreted | ||
| Zinc finger SWIM domain-containing protein 6 | autism spectrum disorder | ||
| Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (hBRM) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2) | Nucleus. | ||
| Transcription initiation factor TFIID subunit 6 (RNA polymerase II TBP-associated factor subunit E) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70) (Transcription initiation factor TFIID 80 kDa subunit) (TAF(II)80) (TAFII-80) (TAFII80) | Nucleus. | ||
| Rho GTPase-activating protein 10 (GTPase regulator associated with focal adhesion kinase 2) (Graf-related protein 2) (Rho-type GTPase-activating protein 10) | Cytoplasm | ||
| DNA repair protein XRCC4 (X-ray repair cross-complementing protein 4) | Nucleus | ||
| E3 SUMO-protein ligase PIAS4 (EC 2.3.2.27) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (RING-type E3 ubiquitin transferase PIAS4) | Nucleus, PML body | ||
| Metastasis-associated protein MTA1 | Isoform Short: Cytoplasm. | ||
| Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3) | Cytoplasm | ||
| Transcriptional repressor p66-beta (GATA zinc finger domain-containing protein 2B) (p66/p68) | Nucleus speckle | ||
| Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) | Nucleus | ||
| Ski-like protein (Ski-related oncogene) (Ski-related protein) | |||
| NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.-) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C) (Ubiquitin-like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3) | |||
| 26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1) | |||
| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H) | Nucleus | ||
| Transaldolase (EC 2.2.1.2) | Cytoplasm | ||
| Rho GTPase-activating protein 24 (Filamin-A-associated RhoGAP) (FilGAP) (RAC1- and CDC42-specific GTPase-activating protein of 72 kDa) (RC-GAP72) (Rho-type GTPase-activating protein 24) (RhoGAP of 73 kDa) (Sarcoma antigen NY-SAR-88) (p73RhoGAP) | |||
| NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (Complex I-9kD) (CI-9kD) (NADH-ubiquinone oxidoreductase 9 kDa subunit) (Renal carcinoma antigen NY-REN-4) | Mitochondrion inner membrane | ||
| Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta) | Nucleus | ||
| T-cell acute lymphocytic leukemia protein 1 (TAL-1) (Class A basic helix-loop-helix protein 17) (bHLHa17) (Stem cell protein) (T-cell leukemia/lymphoma protein 5) | Nucleus | ||
| Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3) | |||
| Methyl-CpG-binding domain protein 2 (Demethylase) (DMTase) (Methyl-CpG-binding protein MBD2) | Nucleus | ||
| Carboxypeptidase E (CPE) (EC 3.4.17.10) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase) | Isoform 1: Cytoplasmic vesicle, secretory vesicle membrane | ||
| LIM homeobox transcription factor 1-beta (LIM/homeobox protein 1.2) (LMX-1.2) (LIM/homeobox protein LMX1B) | Nucleus | ||
| Zinc finger protein 843 | |||
| Myocyte-specific enhancer factor 2B (RSRFR2) (Serum response factor-like protein 2) | Nucleus. | ||
| Protein ATP1B4 (X,K-ATPase subunit beta-m) (X/potassium-transporting ATPase subunit beta-m) | Nucleus inner membrane | ||
| Roundabout homolog 2 | Membrane | ||
| Thyroid receptor-interacting protein 6 (TR-interacting protein 6) (TRIP-6) (Opa-interacting protein 1) (OIP-1) (Zyxin-related protein 1) (ZRP-1) | Cytoplasm, cytoskeleton | ||
| E3 ubiquitin-protein transferase RMND5A (EC 2.3.2.27) (P44CTLH) (Protein RMD5 homolog A) | Nucleus, nucleoplasm | ||
| Zinc finger protein 569 | Nucleus | ||
| Ran-binding protein 10 (RanBP10) | Cytoplasm, cytosol | ||
| HLA class II histocompatibility antigen, DP alpha 1 chain (DP(W3)) (DP(W4)) (HLA-SB alpha chain) (MHC class II DP3-alpha) (MHC class II DPA1) | |||
| Glucose-induced degradation protein 4 homolog (Vacuolar import and degradation protein 24 homolog) | |||
| Ran-binding protein 9 (RanBP9) (BPM-L) (BPM90) (Ran-binding protein M) (RanBPM) (RanBP7) | Cytoplasm | ||
| Tumor necrosis factor ligand superfamily member 13B (B lymphocyte stimulator) (BLyS) (B-cell-activating factor) (BAFF) (Dendritic cell-derived TNF-like molecule) (TNF- and APOL-related leukocyte expressed ligand 1) (TALL-1) (CD antigen CD257) [Cleaved into: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form] | Cell membrane | ||
| Carcinoembryonic antigen-related cell adhesion molecule 21 | Membrane | ||
| Pro-neuregulin-1, membrane-bound isoform (Pro-NRG1) [Cleaved into: Neuregulin-1 (Acetylcholine receptor-inducing activity) (ARIA) (Breast cancer cell differentiation factor p45) (Glial growth factor) (Heregulin) (HRG) (Neu differentiation factor) (Sensory and motor neuron-derived factor)] | |||
| Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1) | |||
| Fibronectin type III domain-containing protein 9 | Membrane | ||
| Reticulon-4 (Foocen) (Neurite outgrowth inhibitor) (Nogo protein) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5) | Endoplasmic reticulum membrane | ||
| Zinc finger protein 205 (Zinc finger protein 210) | Nucleus | ||
| Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein) | lateral sclerosis amyotrophic lateral sclerosis | ||
| LYR motif-containing protein 4 | Mitochondrion | ||
| Calponin-1 (Basic calponin) (Calponin H1, smooth muscle) | |||
| Actin, alpha skeletal muscle (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form] | progressive muscular atrophy | Cytoplasm, cytoskeleton. | |
| Mediator of RNA polymerase II transcription subunit 13-like (Mediator complex subunit 13-like) (Thyroid hormone receptor-associated protein 2) (Thyroid hormone receptor-associated protein complex 240 kDa component-like) | Nucleus | ||
| Condensin complex subunit 1 (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (hCAP-D2) (Non-SMC condensin I complex subunit D2) (XCAP-D2 homolog) | Nucleus | ||
| Coiled-coil alpha-helical rod protein 1 (Alpha-helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8) | Cytoplasm | ||
| HMG domain-containing protein 3 (HMG box-containing protein 3) (Protein SMF) | Nucleus | ||
| Dynamin-binding protein (Scaffold protein Tuba) | Cytoplasm | ||
| Butyrophilin-like protein 8 | Membrane | ||
| Homeobox protein OTX2 (Orthodenticle homolog 2) | Nucleus | ||
| Glycine receptor subunit alpha-2 | Cell junction, synapse, postsynaptic cell membrane | ||
| Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase) | Cytoplasm. | ||
| Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (Epididymis tissue protein Li 169) (TBP-interacting protein of 120 kDa B) (TBP-interacting protein 120B) (p120 CAND2) | Nucleus | ||
| Protein BEX1 (Brain-expressed X-linked protein 1) | |||
| Matrilysin (EC 3.4.24.23) (Matrin) (Matrix metalloproteinase-7) (MMP-7) (Pump-1 protease) (Uterine metalloproteinase) | Secreted, extracellular space, extracellular matrix | ||
| DNA-binding protein inhibitor ID-3 (Class B basic helix-loop-helix protein 25) (bHLHb25) (Helix-loop-helix protein HEIR-1) (ID-like protein inhibitor HLH 1R21) (Inhibitor of DNA binding 3) (Inhibitor of differentiation 3) | Nucleus. | ||
| CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) (Negative regulator of transcription subunit 1 homolog) (NOT1H) (hNOT1) | Cytoplasm, P-body | ||
| NLR family CARD domain-containing protein 4 (CARD, LRR, and NACHT-containing protein) (Clan protein) (Caspase recruitment domain-containing protein 12) (Ice protease-activating factor) (Ipaf) | Cytoplasm | ||
| FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament-binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6) | Cytoplasm, cytoskeleton | ||
| RNA-binding E3 ubiquitin-protein ligase MEX3C (EC 2.3.2.27) (RING finger and KH domain-containing protein 2) (RING finger protein 194) (RING-type E3 ubiquitin transferase MEX3C) | Cytoplasm | ||
| Angiomotin-like protein 1 | Cell junction, tight junction | ||
| Myopalladin (145 kDa sarcomeric protein) | progressive muscular atrophy | Cytoplasm | |
| Ninein-like protein | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| F-actin-capping protein subunit alpha-2 (CapZ alpha-2) | |||
| Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110) | Cytoplasm, cytoskeleton, stress fiber | ||
| Protein Tob1 (Transducer of erbB-2 1) | Cytoplasm | ||
| Ubiquitin-conjugating enzyme E2 D4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D4) (HBUCE1) (Ubiquitin carrier protein D4) (Ubiquitin-protein ligase D4) | |||
| RNA-binding protein 15 (One-twenty two protein 1) (RNA-binding motif protein 15) | Nucleus speckle | ||
| Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N) | Nucleus | ||
| Cannabinoid receptor 1 (CB-R) (CB1) (CANN6) | Cell membrane | ||
| Pleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3) | |||
| Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) | autism spectrum disorder | Membrane | |
| Homeobox protein MOX-2 (Growth arrest-specific homeobox) (Mesenchyme homeobox 2) | Nucleus | ||
| Zinc finger MIZ domain-containing protein 1 (PIAS-like protein Zimp10) (Retinoic acid-induced protein 17) | Nucleus speckle | ||
| RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) | Nucleus speckle | ||
| Ecto-ADP-ribosyltransferase 3 (EC 2.4.2.31) (ADP-ribosyltransferase C2 and C3 toxin-like 3) (ARTC3) (Mono(ADP-ribosyl)transferase 3) (NAD(P)(+)--arginine ADP-ribosyltransferase 3) | Cell membrane | ||
| Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL) | Cytoplasm, cytoskeleton | ||
| Formin-1 (Limb deformity protein homolog) | Nucleus | ||
| Ezrin (Cytovillin) (Villin-2) (p81) | Apical cell membrane | ||
| Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) | Nucleus | ||
| Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Cholecystokinin (CCK) [Cleaved into: Cholecystokinin-58 (CCK58); Cholecystokinin-58 desnonopeptide ((1-49)-CCK58); Cholecystokinin-39 (CCK39); Cholecystokinin-33 (CCK33); Cholecystokinin-25 (CCK25); Cholecystokinin-18 (CCK18); Cholecystokinin-12 (CCK12); Cholecystokinin-8 (CCK8); Cholecystokinin-7 (CCK7); Cholecystokinin-5 (CCK5)] | Secreted. | ||
| Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3) | |||
| Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR) | Cytoplasm | ||
| Zymogen granule protein 16 homolog B | Secreted | ||
| Palladin (SIH002) (Sarcoma antigen NY-SAR-77) | Cytoplasm, cytoskeleton | ||
| Protein arginine N-methyltransferase 3 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3) | Cytoplasm. | ||
| RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN) | Nucleus | ||
| Nucleoside diphosphate kinase 7 (NDK 7) (NDP kinase 7) (EC 2.7.4.6) (nm23-H7) | |||
| DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP) | Nucleus | ||
| Proenkephalin-A [Cleaved into: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); PENK(114-133); PENK(143-183); Met-enkephalin-Arg-Gly-Leu; Leu-enkephalin; PENK(237-258); Met-enkephalin-Arg-Phe] | Secreted. | ||
| NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (54 kDa vimentin-interacting protein) (VIP54) (90 kDa SH3 protein interacting with Nck) (AF3p21) (Dia-interacting protein 1) (DIP-1) (Diaphanous protein-interacting protein) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-interacting protein) | |||
| Aprataxin (EC 3.1.11.7) (EC 3.1.12.2) (Forkhead-associated domain histidine triad-like protein) (FHA-HIT) | autosomal recessive cerebellar ataxia | Nucleus, nucleoplasm | |
| Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase) | |||
| Zinc finger C2HC domain-containing protein 1C | |||
| Telomerase Cajal body protein 1 (WD repeat-containing protein 79) (WD40 repeat-containing protein antisense to TP53 gene) (WRAP53beta) | Nucleus, Cajal body | ||
| Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT) | |||
| LIM domain-containing protein 1 | |||
| ATP synthase subunit f, mitochondrial (ATP synthase membrane subunit f) | Mitochondrion | ||
| Reticulon-4-interacting protein 1, mitochondrial (NOGO-interacting mitochondrial protein) | Mitochondrion outer membrane | ||
| Prostaglandin F2 receptor negative regulator (CD9 partner 1) (CD9P-1) (Glu-Trp-Ile EWI motif-containing protein F) (EWI-F) (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD antigen CD315) | Endoplasmic reticulum membrane | ||
| KN motif and ankyrin repeat domain-containing protein 2 (Ankyrin repeat domain-containing protein 25) (Matrix-remodeling-associated protein 3) (SRC-1-interacting protein) (SIP) (SRC-interacting protein) (SRC1-interacting protein) | Cytoplasm | ||
| Sickle tail protein homolog | Cytoplasm | ||
| Nucleotide exchange factor SIL1 (BiP-associated protein) (BAP) | autosomal recessive cerebellar ataxia | Endoplasmic reticulum lumen | |
| Centrosomal protein of 85 kDa (Cep85) (Coiled-coil domain-containing protein 21) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Heterogeneous nuclear ribonucleoprotein C-like 2 (hnRNP C-like-2) | Nucleus | ||
| Ras-related protein Rab-35 (GTP-binding protein RAY) (Ras-related protein Rab-1C) | Cell membrane | ||
| Crossover junction endonuclease EME1 (EC 3.1.22.-) (MMS4 homolog) (hMMS4) | Nucleus, nucleolus | ||
| Calumenin (Crocalbin) (IEF SSP 9302) | Endoplasmic reticulum membrane | ||
| Lymphocyte antigen 6E (Ly-6E) (Retinoic acid-induced gene E protein) (RIG-E) (Stem cell antigen 2) (SCA-2) (Thymic shared antigen 1) (TSA-1) | Cell membrane | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (Complex I-19kD) (CI-19kD) (Complex I-PGIV) (CI-PGIV) (NADH-ubiquinone oxidoreductase 19 kDa subunit) | Mitochondrion inner membrane | ||
| Protein CYR61 (CCN family member 1) (Cysteine-rich angiogenic inducer 61) (Insulin-like growth factor-binding protein 10) (IBP-10) (IGF-binding protein 10) (IGFBP-10) (Protein GIG1) | Secreted. | ||
| Spatacsin (Colorectal carcinoma-associated protein) (Spastic paraplegia 11 protein) | lateral sclerosis amyotrophic lateral sclerosis | Cytoplasm, cytosol | |
| Protein NEDD1 (Neural precursor cell expressed developmentally down-regulated protein 1) (NEDD-1) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein) | Nucleus | ||
| Voltage-gated potassium channel subunit beta-2 (EC 1.1.1.-) (K(+) channel subunit beta-2) (Kv-beta-2) (hKvbeta2) | Cytoplasm | ||
| Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein) | lateral sclerosis | ||
| Coiled-coil domain-containing protein 24 | |||
| Tetratricopeptide repeat protein 23 (TPR repeat protein 23) (Cervical cancer proto-oncogene 8 protein) (HCC-8) | |||
| Coiled-coil domain-containing protein 14 | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite | ||
| E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (Mulibrey nanism protein) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37) | Cytoplasm, perinuclear region | ||
| Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2) | Cytoplasm | ||
| T-cell leukemia/lymphoma protein 1B (Oncogene TCL-1B) (Oncogene TCL1B) (SYN-1) (Syncytiotrophoblast-specific protein) (TCL1/MTCP1-like protein 1) | |||
| Bromodomain-containing protein 1 (BR140-like protein) (Bromodomain and PHD finger-containing protein 2) | Nucleus | ||
| Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein) | |||
| Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) | Cytoplasm | ||
| C-C motif chemokine 16 (Chemokine CC-4) (HCC-4) (Chemokine LEC) (IL-10-inducible chemokine) (LCC-1) (Liver-expressed chemokine) (Lymphocyte and monocyte chemoattractant) (LMC) (Monotactin-1) (MTN-1) (NCC-4) (Small-inducible cytokine A16) | Secreted. | ||
| Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1) | lateral sclerosis amyotrophic lateral sclerosis multiple system atrophy | Cytoplasm | |
| Signal-regulatory protein gamma (SIRP-gamma) (CD172 antigen-like family member B) (Signal-regulatory protein beta-2) (SIRP-b2) (SIRP-beta-2) (CD antigen CD172g) | Membrane | ||
| Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100) | autosomal recessive cerebellar ataxia | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | |
| GPI transamidase component PIG-S (Phosphatidylinositol-glycan biosynthesis class S protein) | Endoplasmic reticulum membrane | ||
| CCR4-NOT transcription complex subunit 11 | Cytoplasm | ||
| Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2) | |||
| Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| HAUS augmin-like complex subunit 2 (Centrosomal protein of 27 kDa) (Cep27) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Niban-like protein 1 (Meg-3) (Melanoma invasion by ERK) (MINERVA) (Protein FAM129B) | Cytoplasm, cytosol | ||
| Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase) | Cytoplasm | ||
| CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1) (Protein Orbit homolog 1) (hOrbit1) | Cytoplasm, cytoskeleton | ||
| Protein SSUH2 homolog (Protein ssu-2 homolog) | Cytoplasm | ||
| Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) [Cleaved into: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)] | multiple sclerosis | Cell membrane | |
| Vacuolar protein sorting-associated protein 33B (hVPS33B) | Late endosome membrane | ||
| Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2) | Endoplasmic reticulum membrane | ||
| Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein) (Protein Milton) | Cytoplasm | ||
| snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha) (snRNA-activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) | Nucleus | ||
| E3 ubiquitin-protein ligase MIB1 (EC 2.3.2.27) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase MIB1) (Zinc finger ZZ type with ankyrin repeat domain protein 2) | Cytoplasm | ||
| Cadherin-15 (Cadherin-14) (Muscle cadherin) (M-cadherin) | Cell membrane | ||
| G2 and S phase-expressed protein 1 (GTSE-1) (Protein B99 homolog) | |||
| Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44) | |||
| Progesterone-induced-blocking factor 1 (PIBF) (Centrosomal protein of 90 kDa) (CEP90) | autosomal recessive cerebellar ataxia autosomal dominant cerebellar ataxia | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | |
| NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase) | Mitochondrion inner membrane | ||
| Heat shock protein beta-7 (HspB7) (Cardiovascular heat shock protein) (cvHsp) | Cytoplasm | ||
| HAUS augmin-like complex subunit 6 | Cytoplasm, cytoskeleton | ||
| G2/mitotic-specific cyclin-B1 | Cytoplasm | ||
| R-spondin-1 (Roof plate-specific spondin-1) (hRspo1) | Secreted | ||
| Cytoskeleton-associated protein 2 (CTCL tumor antigen se20-10) (Tumor- and microtubule-associated protein) | |||
| HAUS augmin-like complex subunit 8 (HEC1/NDC80-interacting centrosome-associated protein 1) (Sarcoma antigen NY-SAR-48) | Cytoplasm | ||
| N-alpha-acetyltransferase 15, NatA auxiliary subunit (Gastric cancer antigen Ga19) (N-terminal acetyltransferase) (NMDA receptor-regulated protein 1) (Protein tubedown-1) (Tbdn100) | |||
| Hydroxysteroid dehydrogenase-like protein 2 (EC 1.-.-.-) (Short chain dehydrogenase/reductase family 13C member 1) | Peroxisome | ||
| Corepressor interacting with RBPJ 1 (CBF1-interacting corepressor) (Recepin) | |||
| RecQ-mediated genome instability protein 2 (hRMI2) (BLM-associated protein of 18 kDa) (BLAP18) | Nucleus | ||
| Ras-related protein Rab-9A | Cell membrane | ||
| Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) | Endoplasmic reticulum lumen. | ||
| HAUS augmin-like complex subunit 4 | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| 3-ketoacyl-CoA thiolase, peroxisomal (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase) (Peroxisomal 3-oxoacyl-CoA thiolase) | Peroxisome. | ||
| Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP) | Cell junction, adherens junction | ||
| Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase) | Nucleus | ||
| Ras-related protein Rab-5B | Cell membrane | ||
| Alpha-taxilin | |||
| Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (EC 3.1.3.16) (RNA polymerase II-associated protein 2) | Cytoplasm | ||
| Ras-related protein Rab-8A (Oncogene c-mel) | Cell membrane | ||
| Tetraspanin-4 (Tspan-4) (Novel antigen 2) (NAG-2) (Transmembrane 4 superfamily member 7) | Membrane | ||
| Immunoglobulin lambda-like polypeptide 1 (CD179 antigen-like family member B) (Ig lambda-5) (Immunoglobulin omega polypeptide) (Immunoglobulin-related protein 14.1) (CD antigen CD179b) | Secreted | ||
| Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72) | Endoplasmic reticulum lumen | ||
| Outer dense fiber protein 1 (Heat shock protein beta-10) (HspB10) | |||
| Pyridoxal phosphate homeostasis protein (PLP homeostasis protein) (Proline synthase co-transcribed bacterial homolog protein) (Pyridoxal phosphate-binding protein) | |||
| 26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40) | |||
| Cell death-inducing p53-target protein 1 (Cell death involved p53-target) (Cell death-inducing protein) (LITAF-like protein) (Lipopolysaccharide-induced tumor necrosis factor-alpha-like protein) (Transmembrane protein I1) | Late endosome membrane | ||
| Microsomal glutathione S-transferase 3 (Microsomal GST-3) (EC 2.5.1.18) (Microsomal GST-III) | Endoplasmic reticulum membrane | ||
| MAP7 domain-containing protein 3 | Cytoplasm, cytoskeleton, spindle | ||
| SAM pointed domain-containing Ets transcription factor (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets) (Prostate-derived Ets factor) | Nucleus | ||
| Rho guanine nucleotide exchange factor 2 (Guanine nucleotide exchange factor H1) (GEF-H1) (Microtubule-regulated Rho-GEF) (Proliferating cell nucleolar antigen p40) | Cytoplasm, cytoskeleton | ||
| Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein) | Cytoplasm | ||
| Syntaxin-binding protein 3 (Platelet Sec1 protein) (PSP) (Protein unc-18 homolog 3) (Unc18-3) (Protein unc-18 homolog C) (Unc-18C) | Cytoplasm, cytosol | ||
| Calreticulin (CRP55) (Calregulin) (Endoplasmic reticulum resident protein 60) (ERp60) (HACBP) (grp60) | Endoplasmic reticulum lumen | ||
| Protein S100-A4 (Calvasculin) (Metastasin) (Placental calcium-binding protein) (Protein Mts1) (S100 calcium-binding protein A4) | |||
| Ephrin-B2 (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L) | Cell membrane | ||
| Solute carrier family 40 member 1 (Ferroportin-1) (Iron-regulated transporter 1) | Cell membrane | ||
| Alpha-globin transcription factor CP2 (SAA3 enhancer factor) (Transcription factor LSF) | Nucleus | ||
| RNA-binding protein 8A (Binder of OVCA1-1) (BOV-1) (RNA-binding motif protein 8A) (RNA-binding protein Y14) (Ribonucleoprotein RBM8A) | Nucleus | ||
| WD repeat-containing protein 73 | autosomal recessive cerebellar ataxia | Cytoplasm, cytosol | |
| Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (DACAR) (Tumor up-regulated CARD-containing antagonist of CASP9) (TUCAN) | Cytoplasm | ||
| Testis-expressed sequence 37 protein (Testis-specific conserved protein of 21 kDa) | Nucleus | ||
| Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95) | Isoform 1: Cell membrane | ||
| Complement C3 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1) [Cleaved into: Complement C3 beta chain; C3-beta-c (C3bc); Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimulating protein (ASP) (C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2] | Secreted. | ||
| Complement factor H-related protein 5 (FHR-5) | Secreted. | ||
| Terminal nucleotidyltransferase 5B (EC 2.7.7.-) | |||
| RING finger protein 208 | |||
| Mediator of RNA polymerase II transcription subunit 23 (Activator-recruited cofactor 130 kDa component) (ARC130) (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (hSur-2) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130) | Nucleus | ||
| Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18) | Cell membrane | ||
| Transcription initiation protein SPT3 homolog (SPT3-like protein) | Nucleus | ||
| Methylcytosine dioxygenase TET2 (EC 1.14.11.n2) | |||
| Neutrophil defensin 1 (Defensin, alpha 1) (HNP-1) (HP-1) (HP1) [Cleaved into: HP 1-56; Neutrophil defensin 2 (HNP-2) (HP-2) (HP2)] | Secreted. | ||
| ATP-dependent RNA helicase DDX19B (EC 3.6.4.13) (DEAD box RNA helicase DEAD5) (DEAD box protein 19B) | |||
| Collagen alpha-2(IX) chain | Secreted, extracellular space, extracellular matrix | ||
| Huntingtin-associated protein 1 (HAP-1) (Neuroan 1) | Cytoplasm | ||
| Fasciculation and elongation protein zeta-1 (Zygin I) (Zygin-1) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48) | Cell junction, adherens junction | ||
| SLAM family member 7 (CD2 subset 1) (CD2-like receptor-activating cytotoxic cells) (CRACC) (Membrane protein FOAP-12) (Novel Ly9) (Protein 19A) (CD antigen CD319) | Membrane | ||
| Retbindin | Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix | ||
| Phytanoyl-CoA hydroxylase-interacting protein-like | |||
| Protein ABHD11 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 11) (Abhydrolase domain-containing protein 11) (Williams-Beuren syndrome chromosomal region 21 protein) | |||
| Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1) | Cell membrane, sarcolemma | ||
| Coenzyme Q-binding protein COQ10 homolog B, mitochondrial | Mitochondrion inner membrane | ||
| Mitochondrial import inner membrane translocase subunit Tim8 B (DDP-like protein) (Deafness dystonia protein 2) | Mitochondrion inner membrane | ||
| Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (CybS) (CII-4) (QPs3) (Succinate dehydrogenase complex subunit D) (Succinate-ubiquinone oxidoreductase cytochrome b small subunit) (Succinate-ubiquinone reductase membrane anchor subunit) | Mitochondrion inner membrane | ||
| Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (Aging-associated gene 10 protein) (HCV NS2 trans-regulated protein) (NS2TP) | Parkinson disease | Nucleus | |
| Presequence protease, mitochondrial (hPreP) (EC 3.4.24.-) (Pitrilysin metalloproteinase 1) (Metalloprotease 1) (hMP1) | Mitochondrion matrix | ||
| Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt)) | Mitochondrion. | ||
| Stomatin-like protein 2, mitochondrial (SLP-2) (EPB72-like protein 2) (Paraprotein target 7) (Paratarg-7) | Cell membrane | ||
| TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit) | autosomal dominant cerebellar ataxia Huntington disease | Nucleus | |
| E3 ubiquitin-protein ligase RBBP6 (EC 2.3.2.27) (Proliferation potential-related protein) (Protein P2P-R) (RING-type E3 ubiquitin transferase RBBP6) (Retinoblastoma-binding Q protein 1) (RBQ-1) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis) | |||
| Symplekin | |||
| Neurexin-2 (Neurexin II-alpha) (Neurexin-2-alpha) | Membrane | ||
| Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73) | Nucleus | ||
| Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2) | |||
| Transcription initiation factor TFIID subunit 7 (RNA polymerase II TBP-associated factor subunit F) (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55) | Nucleus | ||
| Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20/15 kDa subunits) (TAFII-20/TAFII-15) (TAFII20/TAFII15) | Nucleus | ||
| Ras-related GTP-binding protein A (Rag A) (RagA) (Adenovirus E3 14.7 kDa-interacting protein 1) (FIP-1) | Cytoplasm | ||
| 2'-5'-oligoadenylate synthase 3 ((2-5')oligo(A) synthase 3) (2-5A synthase 3) (EC 2.7.7.84) (p100 OAS) (p100OAS) | Cytoplasm | ||
| Lipocalin-15 | Secreted | ||
| E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) | Cytoplasm, P-body | ||
| Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1) | Nucleus | ||
| Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor) (Nuclear receptor subfamily 1 group I member 1) | Nucleus | ||
| Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1) | Cytoplasm | ||
| Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK) | Cytoplasm | ||
| Mitochondrial import inner membrane translocase subunit Tim17-A (Inner membrane preprotein translocase Tim17a) | Mitochondrion inner membrane | ||
| Cytoplasmic tRNA 2-thiolation protein 2 (Cytosolic thiouridylase subunit 2) | Cytoplasm. | ||
| Protein FAM219A | |||
| Iron-sulfur protein NUBPL (IND1 homolog) (Nucleotide-binding protein-like) (huInd1) | Parkinson disease | Mitochondrion | |
| Saccharopine dehydrogenase-like oxidoreductase (EC 1.-.-.-) | |||
| Cyclin-D1-binding protein 1 (Grap2 and cyclin-D-interacting protein) (Human homolog of Maid) | Cytoplasm | ||
| Nucleoporin p58/p45 (58 kDa nucleoporin) (Nucleoporin-like protein 1) | Nucleus, nuclear pore complex | ||
| NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3) | |||
| Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43) | Cell membrane, sarcolemma | ||
| Malignant T-cell-amplified sequence 1 (MCT-1) (Multiple copies T-cell malignancies) | Cytoplasm | ||
| KIF1-binding protein | Cytoplasm, cytoskeleton | ||
| Tensin-2 (EC 3.1.3.-) (C1 domain-containing phosphatase and tensin homolog) (C1-TEN) (Tensin-like C1 domain-containing phosphatase) | Cell junction, focal adhesion | ||
| RNA helicase aquarius (EC 3.6.4.13) (Intron-binding protein of 160 kDa) (IBP160) | Nucleus | ||
| ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial | Mitochondrion | ||
| 40S ribosomal protein S23 (Small ribosomal subunit protein uS12) | autism spectrum disorder | Cytoplasm, cytosol | |
| Proteasome subunit beta type-4 (EC 3.4.25.1) (26 kDa prosomal protein) (HsBPROS26) (PROS-26) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome beta chain) (Proteasome chain 3) (HsN3) | Cytoplasm | ||
| Fasciculation and elongation protein zeta-2 (Zygin II) (Zygin-2) | |||
| Potassium voltage-gated channel subfamily H member 2 (Eag homolog) (Ether-a-go-go-related gene potassium channel 1) (ERG-1) (Eag-related protein 1) (Ether-a-go-go-related protein 1) (H-ERG) (hERG-1) (hERG1) (Voltage-gated potassium channel subunit Kv11.1) | Cell membrane | ||
| Kynurenine--oxoglutarate transaminase 3 (EC 2.6.1.7) (Cysteine-S-conjugate beta-lyase 2) (EC 4.4.1.13) (Kynurenine aminotransferase 3) (Kynurenine aminotransferase III) (KATIII) (Kynurenine--glyoxylate transaminase) (EC 2.6.1.63) (Kynurenine--oxoglutarate transaminase III) | |||
| Syntaxin-18 (Cell growth-inhibiting gene 9 protein) | Endoplasmic reticulum membrane | ||
| Programmed cell death protein 6 (Apoptosis-linked gene 2 protein homolog) (ALG-2) | Endoplasmic reticulum membrane | ||
| Protein phosphatase 1E (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase N) (CaMKP-N) (CaMKP-nucleus) (CaMKN) (Partner of PIX 1) (Partner of PIX-alpha) (Partner of PIXA) | Nucleus | ||
| Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4) | Nucleus | ||
| Elongation factor 1-delta (EF-1-delta) (Antigen NY-CO-4) | Isoform 2: Nucleus | ||
| Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Triose-phosphate isomerase) | |||
| Cryptochrome-1 | Cytoplasm | ||
| Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2) | autism spectrum disorder | Cell membrane | |
| Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1) | Nucleus | ||
| Utrophin (Dystrophin-related protein 1) (DRP-1) | |||
| Unconventional myosin-Ib (MYH-1c) (Myosin I alpha) (MMI-alpha) (MMIa) | |||
| Inhibitor of growth protein 3 (p47ING3) | Nucleus. | ||
| F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19) | |||
| SOSS complex subunit B1 (Nucleic acid-binding protein 2) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2B) (Sensor of single-strand DNA complex subunit B1) (Sensor of ssDNA subunit B1) (SOSS-B1) (Single-stranded DNA-binding protein 1) (hSSB1) | Nucleus | ||
| Echinoderm microtubule-associated protein-like 1 (EMAP-1) (HuEMAP-1) | Cytoplasm | ||
| Arrestin domain-containing protein 3 (TBP-2-like inducible membrane protein) (TLIMP) | Cytoplasm | ||
| 60S ribosomal protein L32 (Large ribosomal subunit protein eL32) | |||
| Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6) | Nucleus | ||
| Spermatid-specific manchette-related protein 1 (Ciliated bronchial epithelial protein 1) (Testis development protein NYD-SP22) | Cytoplasm, cytoskeleton | ||
| Uncharacterized protein C17orf77 | Secreted | ||
| Metastasis suppressor protein 1 (Metastasis suppressor YGL-1) (Missing in metastasis protein) | Cytoplasm, cytoskeleton. | ||
| C4b-binding protein beta chain | Secreted. | ||
| Proteasome subunit alpha type-6 (EC 3.4.25.1) (27 kDa prosomal protein) (PROS-27) (p27K) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain) | Cytoplasm | ||
| Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK-6A) (Cytokeratin-6D) (CK-6D) (Keratin-6A) (K6A) (Type-II keratin Kb6) (allergen Hom s 5) | |||
| 39S ribosomal protein S30, mitochondrial (MRP-S30) (S30mt) (Mitochondrial large ribosomal subunit protein mL65) (Mitochondrial large ribosomal subunit protein mS30) (Programmed cell death protein 9) | Mitochondrion | ||
| Structure-specific endonuclease subunit SLX1 (EC 3.1.-.-) (GIY-YIG domain-containing protein 1) | Nucleus | ||
| Proteasome assembly chaperone 3 (PAC-3) (hPAC3) | |||
| Testis-specific Y-encoded-like protein 4 (TSPY-like protein 4) | |||
| Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Peroxiredoxin-6 (EC 1.11.1.15) (1-Cys peroxiredoxin) (1-Cys PRX) (24 kDa protein) (Acidic calcium-independent phospholipase A2) (aiPLA2) (EC 3.1.1.4) (Antioxidant protein 2) (Liver 2D page spot 40) (Non-selenium glutathione peroxidase) (NSGPx) (Red blood cells page spot 12) | Cytoplasm | ||
| Drebrin-like protein (Cervical SH3P7) (Cervical mucin-associated protein) (Drebrin-F) (HPK1-interacting protein of 55 kDa) (HIP-55) (SH3 domain-containing protein 7) | Cytoplasm, cytoskeleton | ||
| Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator) | autosomal dominant cerebellar ataxia | Cell membrane | |
| Proline-rich transmembrane protein 2 (Dispanin subfamily B member 3) (DSPB3) | Cell membrane | ||
| Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.4.19.12) (Deubiquitinating enzyme 47) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) | Cytoplasm | ||
| Scavenger receptor class B member 1 (SRB1) (CD36 and LIMPII analogous 1) (CLA-1) (CD36 antigen-like 1) (Collagen type I receptor, thrombospondin receptor-like 1) (SR-BI) (CD antigen CD36) | Cell membrane | ||
| b(0,+)-type amino acid transporter 1 (b(0,+)AT1) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9) | Apical cell membrane | ||
| Peroxiredoxin-2 (EC 1.11.1.15) (Natural killer cell-enhancing factor B) (NKEF-B) (PRP) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) | Alzheimer disease | Cytoplasm | |
| Ankyrin repeat and SOCS box protein 2 (ASB-2) | |||
| Arginine/serine-rich coiled-coil protein 2 | |||
| E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2) | Lewy body dementia Parkinson disease | Cytoplasm, cytosol | |
| Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog) | Nucleus | ||
| Peptidyl-glycine alpha-amidating monooxygenase (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (PHM) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)] | Isoform 1: Membrane | ||
| Neuroserpin (Peptidase inhibitor 12) (PI-12) (Serpin I1) | familial encephalopathy with neuroserpin inclusion bodies | Secreted | |
| Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2) | Cytoplasm, cytoskeleton | ||
| 60S ribosomal protein L18a (Large ribosomal subunit protein eL20) | |||
| Calmodulin-2 | Cytoplasm, cytoskeleton, spindle | ||
| Coiled-coil domain-containing protein 125 (Protein kenae) | Cytoplasm | ||
| Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (hMAD-3) (JV15-2) (SMAD family member 3) (SMAD 3) (Smad3) (hSMAD3) | Cytoplasm | ||
| Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309) | Cell junction | ||
| NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2) | Nucleus | ||
| Oxysterol-binding protein-related protein 10 (ORP-10) (OSBP-related protein 10) | Cytoplasm, cytoskeleton | ||
| Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP) | Cytoplasm | ||
| BRISC and BRCA1-A complex member 2 (BRCA1-A complex subunit BRE) (BRCA1/BRCA2-containing complex subunit 45) (Brain and reproductive organ-expressed protein) | Cytoplasm | ||
| Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 4) | |||
| E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Inverted CCAAT box-binding protein of 90 kDa) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (HuNp95) (hNp95) (RING finger protein 106) (RING-type E3 ubiquitin transferase UHRF1) (Transcription factor ICBP90) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (hUHRF1) (Ubiquitin-like-containing PHD and RING finger domains protein 1) | Nucleus | ||
| Transcription factor AP-4 (Activating enhancer-binding protein 4) (Class C basic helix-loop-helix protein 41) (bHLHc41) | Nucleus. | ||
| Polyadenylate-binding protein-interacting protein 2 (PABP-interacting protein 2) (PAIP-2) (Poly(A)-binding protein-interacting protein 2) | Cytoplasm | ||
| Transmembrane channel-like protein 1 (Transmembrane cochlear-expressed protein 1) | Cell membrane | ||
| Galectin-8 (Gal-8) (Po66 carbohydrate-binding protein) (Po66-CBP) (Prostate carcinoma tumor antigen 1) (PCTA-1) | Cytoplasmic vesicle | ||
| Phosphatidylethanolamine-binding protein 1 (PEBP-1) (HCNPpp) (Neuropolypeptide h3) (Prostatic-binding protein) (Raf kinase inhibitor protein) (RKIP) [Cleaved into: Hippocampal cholinergic neurostimulating peptide (HCNP)] | Cytoplasm | ||
| Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1) | Nucleus, PML body | ||
| Bcl-2-like protein 13 (Bcl2-L-13) (Bcl-rambo) (Protein Mil1) | Isoform 2: Mitochondrion membrane | ||
| Zinc-alpha-2-glycoprotein (Zn-alpha-2-GP) (Zn-alpha-2-glycoprotein) | Secreted. | ||
| 60S ribosomal protein L27a (Large ribosomal subunit protein uL15) | |||
| Nexilin (F-actin-binding protein) (Nelin) | Cytoplasm, cytoskeleton | ||
| Ubiquitin/ISG15-conjugating enzyme E2 L6 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L6) (Retinoic acid-induced gene B protein) (RIG-B) (UbcH8) (Ubiquitin carrier protein L6) (Ubiquitin-protein ligase L6) | |||
| Protein reprimo | Cytoplasm | ||
| Interferon regulatory factor 3 (IRF-3) | Cytoplasm | ||
| Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (Snake venom-like protease) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b) | Membrane | ||
| Glycogen [starch] synthase, muscle (EC 2.4.1.11) | |||
| Mediator of RNA polymerase II transcription subunit 6 (Activator-recruited cofactor 33 kDa component) (ARC33) (Mediator complex subunit 6) (hMed6) (Renal carcinoma antigen NY-REN-28) | Nucleus. | ||
| Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS) | Isoform Cytoplasmic: Cytoplasm, cytosol | ||
| Pre-mRNA-splicing factor SPF27 (Breast carcinoma-amplified sequence 2) (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27) | Nucleus, nucleolus | ||
| Dexamethasone-induced Ras-related protein 1 (Activator of G-protein signaling 1) | Cell membrane | ||
| rRNA methyltransferase 3, mitochondrial (EC 2.1.1.-) (16S rRNA (guanosine(1370)-2'-O)-methyltransferase) (16S rRNA [Gm1370] 2'-O-methyltransferase) (RNA methyltransferase-like protein 1) | Mitochondrion | ||
| 60S ribosomal protein L34 (Large ribosomal subunit protein eL34) | Cytoplasm, cytosol | ||
| Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') | |||
| Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Lung-specific protein TSA1902) | |||
| 60S ribosomal protein L10-like (Large ribosomal subunit protein uL16-like) | |||
| Neuronal migration protein doublecortin (Doublin) (Lissencephalin-X) (Lis-X) | Cytoplasm | ||
| Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (Cell proliferation-inducing gene 55 protein) (NCBP 20 kDa subunit) (CBP20) (NCBP-interacting protein 1) (NIP1) | Nucleus | ||
| G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 oncogene) | Nucleus | ||
| Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (HP43.8KD) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) | |||
| Histone H1x | Nucleus | ||
| F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3) | Membrane | ||
| 60S ribosomal protein L28 (Large ribosomal subunit protein eL28) | |||
| Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16) | Cytoplasm | ||
| Ubiquitin-conjugating enzyme E2 G1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G1) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed] | |||
| Ubiquitin-conjugating enzyme E2 L3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L3) (L-UBC) (UbcH7) (Ubiquitin carrier protein L3) (Ubiquitin-conjugating enzyme E2-F1) (Ubiquitin-protein ligase L3) | Nucleus | ||
| Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase A) (IP3 3-kinase A) (IP3K A) (InsP 3-kinase A) | |||
| TNF receptor-associated factor 5 (RING finger protein 84) | Cytoplasm | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (13 kDa differentiation-associated protein) (Complex I-B17.2) (CI-B17.2) (CIB17.2) (NADH-ubiquinone oxidoreductase subunit B17.2) | Parkinson disease | Mitochondrion inner membrane | |
| 4-hydroxybenzoate polyprenyltransferase, mitochondrial (4-HB polyprenyltransferase) (EC 2.5.1.39) (4-hydroxybenzoate decaprenyltransferase) (COQ2 homolog) (hCOQ2) (Para-hydroxybenzoate--polyprenyltransferase) (PHB:PPT) (PHB:polyprenyltransferase) | autosomal recessive cerebellar ataxia multiple system atrophy olivopontocerebellar atrophy | Mitochondrion inner membrane | |
| Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial (Protein N27C7-4) | lateral sclerosis progressive muscular atrophy amyotrophic lateral sclerosis | Mitochondrion intermembrane space | |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8 | Mitochondrion | ||
| Nucleoside diphosphate kinase, mitochondrial (NDK) (NDP kinase, mitochondrial) (EC 2.7.4.6) (Nucleoside diphosphate kinase D) (NDPKD) (nm23-H4) | Mitochondrion intermembrane space | ||
| Myelin protein P0 (Myelin peripheral protein) (MPP) (Myelin protein zero) | progressive muscular atrophy | Cell membrane | |
| Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (Coenzyme Q protein 8A) (aarF domain-containing protein kinase 3) | autosomal recessive cerebellar ataxia | Mitochondrion | |
| OCIA domain-containing protein 1 (Ovarian cancer immunoreactive antigen domain containing 1) (Ovarian carcinoma immunoreactive antigen) | Endosome | ||
| Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast-1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2) | Nucleus. | ||
| Transcription factor E2-alpha (Class B basic helix-loop-helix protein 21) (bHLHb21) (Immunoglobulin enhancer-binding factor E12/E47) (Immunoglobulin transcription factor 1) (Kappa-E2-binding factor) (Transcription factor 3) (TCF-3) (Transcription factor ITF-1) | Nucleus. | ||
| Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) | Cytoplasm | ||
| Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (EC 3.1.3.27) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase) (Protein-tyrosine phosphatase mitochondrial 1) (EC 3.1.3.16) (EC 3.1.3.48) | Mitochondrion inner membrane | ||
| STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase) | Nucleus | ||
| Protein S100-A1 (S-100 protein alpha chain) (S-100 protein subunit alpha) (S100 calcium-binding protein A1) | Cytoplasm | ||
| Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon) | Cytoplasm | ||
| Syntaxin-binding protein 1 (MUNC18-1) (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) | Cytoplasm, cytosol | ||
| Gap junction alpha-3 protein (Connexin-46) (Cx46) | Cell membrane | ||
| Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL) | Cytoplasm | ||
| 5-hydroxytryptamine receptor 3C (5-HT3-C) (5-HT3C) (Serotonin receptor 3C) | Cell membrane | ||
| Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p) | |||
| Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B) | |||
| HLA class II histocompatibility antigen, DR beta 5 chain (DR beta-5) (DR2-beta-2) (Dw2) (MHC class II antigen DRB5) | Cell membrane | ||
| Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c) | autism spectrum disorder | Cell membrane | |
| Signal transducer CD24 (Small cell lung carcinoma cluster 4 antigen) (CD antigen CD24) | multiple sclerosis | Cell membrane | |
| Nuclear receptor coactivator 1 (NCoA-1) (EC 2.3.1.48) (Class E basic helix-loop-helix protein 74) (bHLHe74) (Protein Hin-2) (RIP160) (Renal carcinoma antigen NY-REN-52) (Steroid receptor coactivator 1) (SRC-1) | Nucleus | ||
| Transmembrane protein 185A (Protein FAM11A) | Cell projection, dendrite | ||
| Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N) | Cytoplasm | ||
| Anthrax toxin receptor 1 (Tumor endothelial marker 8) | Cell membrane | ||
| Charged multivesicular body protein 2b (CHMP2.5) (Chromatin-modifying protein 2b) (CHMP2b) (Vacuolar protein sorting-associated protein 2-2) (Vps2-2) (hVps2-2) | lateral sclerosis amyotrophic lateral sclerosis | Cytoplasm, cytosol | |
| Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) | Cytoplasm | ||
| Transmembrane protein 60 | Membrane | ||
| Centrosomal protein of 41 kDa (Cep41) (Testis-specific gene A14 protein) | autosomal recessive cerebellar ataxia autism spectrum disorder | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | |
| Sodium-coupled neutral amino acid transporter 2 (Amino acid transporter A2) (Protein 40-9-1) (Solute carrier family 38 member 2) (System A amino acid transporter 2) (System A transporter 1) (System N amino acid transporter 2) | Cell membrane | ||
| Monocyte differentiation antigen CD14 (Myeloid cell-specific leucine-rich glycoprotein) (CD antigen CD14) [Cleaved into: Monocyte differentiation antigen CD14, urinary form; Monocyte differentiation antigen CD14, membrane-bound form] | Cell membrane | ||
| Sorting nexin-3 (Protein SDP3) | Early endosome | ||
| Putative uncharacterized protein encoded by LINC00518 | |||
| Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)] | Cell membrane | ||
| Mediator of RNA polymerase II transcription subunit 1 (Activator-recruited cofactor 205 kDa component) (ARC205) (Mediator complex subunit 1) (Peroxisome proliferator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TR-interacting protein 2) (TRIP-2) (Vitamin D receptor-interacting protein complex component DRIP205) (p53 regulatory protein RB18A) | Nucleus | ||
| Acyl-coenzyme A synthetase ACSM1, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 1) (Butyrate--CoA ligase 1) (Butyryl-coenzyme A synthetase 1) (Lipoate-activating enzyme) (Middle-chain acyl-CoA synthetase 1) | Mitochondrion matrix | ||
| Dipeptidyl peptidase 8 (DP8) (EC 3.4.14.5) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1) (Dipeptidyl peptidase VIII) (DPP VIII) (Prolyl dipeptidase DPP8) | Cytoplasm | ||
| G-protein coupled receptor-associated sorting protein 1 (GASP-1) | Cytoplasm | ||
| C-X-C motif chemokine 9 (Gamma-interferon-induced monokine) (Monokine induced by interferon-gamma) (HuMIG) (MIG) (Small-inducible cytokine B9) | Secreted. | ||
| Mothers against decapentaplegic homolog 7 (MAD homolog 7) (Mothers against DPP homolog 7) (Mothers against decapentaplegic homolog 8) (MAD homolog 8) (Mothers against DPP homolog 8) (SMAD family member 7) (SMAD 7) (Smad7) (hSMAD7) | Nucleus | ||
| Mothers against decapentaplegic homolog 5 (MAD homolog 5) (Mothers against DPP homolog 5) (JV5-1) (SMAD family member 5) (SMAD 5) (Smad5) (hSmad5) | |||
| Copine-2 (Copine II) | Cytoplasm | ||
| Ribose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (PPRibP) (Phosphoribosyl pyrophosphate synthase I) (PRS-I) | |||
| Menin | Nucleus | ||
| Galectin-12 (Gal-12) (Galectin-related inhibitor of proliferation) | Nucleus. | ||
| Tektin-4 | Cell projection, cilium, flagellum | ||
| DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT) | autosomal dominant cerebellar ataxia | Nucleus | |
| Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.43) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2) | Nucleus | ||
| Steroidogenic factor 1 (SF-1) (STF-1) (hSF-1) (Adrenal 4-binding protein) (Fushi tarazu factor homolog 1) (Nuclear receptor subfamily 5 group A member 1) (Steroid hormone receptor Ad4BP) | Nucleus | ||
| Tax1-binding protein 1 (TRAF6-binding protein) | |||
| V-type proton ATPase subunit B, brain isoform (V-ATPase subunit B 2) (Endomembrane proton pump 58 kDa subunit) (HO57) (Vacuolar proton pump subunit B 2) | |||
| UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) | Alzheimer disease | Nucleus | |
| Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.43) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1) | Nucleus speckle | ||
| Myoferlin (Fer-1-like protein 3) | |||
| 26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1) | Cytoplasm | ||
| Protein arginine N-methyltransferase 2 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT2) | |||
| Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox) | Cytoplasm, cytosol | ||
| Homeobox protein EMX2 (Empty spiracles homolog 2) (Empty spiracles-like protein 2) | Nucleus | ||
| RING finger and CHY zinc finger domain-containing protein 1 (EC 2.3.2.27) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (RING finger protein 199) (RING-type E3 ubiquitin transferase RCHY1) (Zinc finger protein 363) (p53-induced RING-H2 protein) (hPirh2) | Nucleus | ||
| Protein CLN8 | Endoplasmic reticulum membrane | ||
| UHRF1-binding protein 1 (ICBP90-binding protein 1) (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) | |||
| Cytochrome b-c1 complex subunit 1, mitochondrial (Complex III subunit 1) (Core protein I) (Ubiquinol-cytochrome-c reductase complex core protein 1) | Mitochondrion inner membrane. | ||
| Succinate--hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) (Dermal papilla-derived protein 13) (SuccinylCoA:glutarate-CoA transferase) | Mitochondrion | ||
| Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (EC 1.14.13.-) (Coenzyme Q10 monooxygenase 6) | Mitochondrion inner membrane | ||
| Coiled-coil domain-containing protein 167 | Membrane | ||
| Laminin subunit beta-2 (Laminin B1s chain) (Laminin-11 subunit beta) (Laminin-14 subunit beta) (Laminin-15 subunit beta) (Laminin-3 subunit beta) (Laminin-4 subunit beta) (Laminin-7 subunit beta) (Laminin-9 subunit beta) (S-laminin subunit beta) (S-LAM beta) | |||
| Electron transfer flavoprotein regulatory factor 1 (LYR motif-containing protein 5) | Mitochondrion | ||
| Caspase-9 (CASP-9) (EC 3.4.22.62) (Apoptotic protease Mch-6) (Apoptotic protease-activating factor 3) (APAF-3) (ICE-like apoptotic protease 6) (ICE-LAP6) [Cleaved into: Caspase-9 subunit p35; Caspase-9 subunit p10] | |||
| Mitochondrial mRNA pseudouridine synthase TRUB2 (EC 5.4.99.-) | Mitochondrion matrix | ||
| Coiled-coil domain-containing protein 58 | |||
| Voltage-dependent anion-selective channel protein 1 (VDAC-1) (hVDAC1) (Outer mitochondrial membrane protein porin 1) (Plasmalemmal porin) (Porin 31HL) (Porin 31HM) | Mitochondrion outer membrane | ||
| Alanine--tRNA ligase, mitochondrial (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) | autosomal recessive cerebellar ataxia | Mitochondrion | |
| Lysophosphatidic acid phosphatase type 6 (EC 3.1.3.2) (Acid phosphatase 6, lysophosphatidic) (Acid phosphatase-like protein 1) (PACPL1) | Mitochondrion | ||
| 5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.13.-) (Timing protein clk-1 homolog) (Ubiquinone biosynthesis monooxygenase COQ7) | progressive muscular atrophy | Mitochondrion inner membrane | |
| Spermatogenesis-associated protein 20 (Sperm-specific protein 411) (Ssp411) | Secreted | ||
| Cytochrome c1, heme protein, mitochondrial (Complex III subunit 4) (Complex III subunit IV) (Cytochrome b-c1 complex subunit 4) (Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit) (Cytochrome c-1) | Mitochondrion inner membrane | ||
| NADPH-dependent diflavin oxidoreductase 1 (EC 1.18.1.-) (NADPH-dependent FMN and FAD-containing oxidoreductase) (Novel reductase 1) | Cytoplasm, perinuclear region | ||
| 39S ribosomal protein L15, mitochondrial (L15mt) (MRP-L15) (Mitochondrial large ribosomal subunit protein uL15m) | Mitochondrion | ||
| B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3) | Nucleus | ||
| E3 ubiquitin-protein ligase TRAIP (EC 2.3.2.27) (RING finger protein 206) (RING-type E3 ubiquitin transferase TRAIP) (TRAF-interacting protein) | Cytoplasm | ||
| Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I) | |||
| Sharpin (Shank-associated RH domain-interacting protein) (Shank-interacting protein-like 1) (hSIPL1) | Cytoplasm, cytosol | ||
| Serine/threonine-protein phosphatase 2A activator (EC 5.2.1.8) (PP2A, subunit B', PR53 isoform) (Phosphotyrosyl phosphatase activator) (PTPA) (Serine/threonine-protein phosphatase 2A regulatory subunit 4) (Serine/threonine-protein phosphatase 2A regulatory subunit B') | Cytoplasm | ||
| Myelin P2 protein (Peripheral myelin protein 2) | Cytoplasm | ||
| Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2) | Nucleus | ||
| CAP-Gly domain-containing linker protein 3 (Cytoplasmic linker protein 170-related 59 kDa protein) (CLIP-170-related 59 kDa protein) (CLIPR-59) | Cell membrane | ||
| Zinc finger protein 124 (Zinc finger protein HZF-16) | Nucleus | ||
| Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1) | Cytoplasm | ||
| Sphingosine kinase 1 (SK 1) (SPK 1) (EC 2.7.1.91) | Cytoplasm | ||
| 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (EC 2.1.1.201) (Ubiquinone biosynthesis methyltransferase COQ5) | Mitochondrion inner membrane | ||
| C-C motif chemokine 1 (Small-inducible cytokine A1) (T lymphocyte-secreted protein I-309) | Secreted. | ||
| Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17) | Cell membrane, sarcolemma | ||
| Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17) | Cell junction, synapse | ||
| Ubiquitin-conjugating enzyme E2 S (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme S) (E2-EPF) (Ubiquitin carrier protein S) (Ubiquitin-conjugating enzyme E2-24 kDa) (Ubiquitin-conjugating enzyme E2-EPF5) (Ubiquitin-protein ligase S) | |||
| Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 | Membrane | ||
| E3 SUMO-protein ligase ZNF451 (EC 2.3.2.-) (Coactivator for steroid receptors) (E3 SUMO-protein transferase ZNF451) (Zinc finger protein 451) | Nucleus | ||
| Extracellular matrix protein 1 (Secretory component p85) | Secreted, extracellular space, extracellular matrix. | ||
| Stathmin (Leukemia-associated phosphoprotein p18) (Metablastin) (Oncoprotein 18) (Op18) (Phosphoprotein p19) (pp19) (Prosolin) (Protein Pr22) (pp17) | Cytoplasm, cytoskeleton. | ||
| DBF4-type zinc finger-containing protein 2 | |||
| Complexin-1 (Complexin I) (CPX I) (Synaphin-2) | Cytoplasm, cytosol | ||
| MAGUK p55 subfamily member 5 | |||
| CKLF-like MARVEL transmembrane domain-containing protein 5 (Chemokine-like factor superfamily member 5) | Membrane | ||
| Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2) | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane | ||
| Type-1 angiotensin II receptor-associated protein (AT1 receptor-associated protein) | Endoplasmic reticulum membrane | ||
| Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein) | Cytoplasm, perinuclear region | ||
| Interleukin-7 (IL-7) | Secreted. | ||
| Syntaxin-1A (Neuron-specific antigen HPC-1) | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane | ||
| Transmembrane protein 106B | lateral sclerosis amyotrophic lateral sclerosis | Late endosome membrane | |
| Tetratricopeptide repeat protein 21B (TPR repeat protein 21B) (Intraflagellar transport 139 homolog) | Cytoplasm, cytoskeleton, cilium axoneme | ||
| DNA-directed RNA polymerase III subunit RPC3 (RNA polymerase III subunit C3) (DNA-directed RNA polymerase III subunit C) (RNA polymerase III 62 kDa subunit) (RPC62) | Nucleus | ||
| Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) | Cytoplasm | ||
| Sjoegren syndrome/scleroderma autoantigen 1 (Autoantigen p27) | |||
| Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2) | |||
| Perilipin-3 (47 kDa mannose 6-phosphate receptor-binding protein) (47 kDa MPR-binding protein) (Cargo selection protein TIP47) (Mannose-6-phosphate receptor-binding protein 1) (Placental protein 17) (PP17) | Cytoplasm | ||
| Protein lifeguard 4 (Golgi anti-apoptotic protein) (Protein S1R) (Transmembrane BAX inhibitor motif-containing protein 4) (Z-protein) | Golgi apparatus membrane | ||
| Eukaryotic translation initiation factor 3 subunit F (eIF3f) (Deubiquitinating enzyme eIF3f) (EC 3.4.19.12) (Eukaryotic translation initiation factor 3 subunit 5) (eIF-3-epsilon) (eIF3 p47) | Cytoplasm | ||
| Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116) | Cytoplasm | ||
| Intercellular adhesion molecule 1 (ICAM-1) (Major group rhinovirus receptor) (CD antigen CD54) | Membrane | ||
| RNA polymerase I-specific transcription initiation factor RRN3 (Transcription initiation factor IA) (TIF-IA) | Nucleus, nucleolus | ||
| Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170) (Protein H105e3) | Endoplasmic reticulum membrane | ||
| Eukaryotic translation initiation factor 3 subunit H (eIF3h) (Eukaryotic translation initiation factor 3 subunit 3) (eIF-3-gamma) (eIF3 p40 subunit) | Cytoplasm | ||
| Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) | autosomal recessive cerebellar ataxia | Membrane | |
| Inhibin beta A chain (Activin beta-A chain) (Erythroid differentiation protein) (EDF) | Secreted. | ||
| Chordin-like protein 2 (Breast tumor novel factor 1) (BNF-1) (Chordin-related protein 2) | Isoform 1: Secreted | ||
| Tubulin alpha-3E chain (Alpha-tubulin 3E) [Cleaved into: Detyrosinated tubulin alpha-3E chain] | Cytoplasm, cytoskeleton | ||
| Lysophosphatidic acid receptor 6 (LPA receptor 6) (LPA-6) (Oleoyl-L-alpha-lysophosphatidic acid receptor) (P2Y purinoceptor 5) (P2Y5) (Purinergic receptor 5) (RB intron encoded G-protein coupled receptor) | Cell membrane | ||
| INO80 complex subunit B (High mobility group AT-hook 1-like 4) (IES2 homolog) (hIes2) (PAP-1-associated protein 1) (PAPA-1) (Zinc finger HIT domain-containing protein 4) | Nucleus | ||
| Glucosamine-6-phosphate isomerase 1 (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase 1) (GNPDA 1) (GlcN6P deaminase 1) (Oscillin) | Cytoplasm | ||
| Chloride intracellular channel protein 4 (Intracellular chloride ion channel protein p64H1) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| SUMO-activating enzyme subunit 2 (EC 2.3.2.-) (Anthracycline-associated resistance ARX) (Ubiquitin-like 1-activating enzyme E1B) (Ubiquitin-like modifier-activating enzyme 2) | |||
| Prefoldin subunit 2 | Nucleus | ||
| Developmentally-regulated GTP-binding protein 1 (DRG-1) (Neural precursor cell expressed developmentally down-regulated protein 3) (NEDD-3) | Cytoplasm | ||
| Annexin A2 (Annexin II) (Annexin-2) (Calpactin I heavy chain) (Calpactin-1 heavy chain) (Chromobindin-8) (Lipocortin II) (Placental anticoagulant protein IV) (PAP-IV) (Protein I) (p36) | Secreted, extracellular space, extracellular matrix, basement membrane | ||
| Electron transfer flavoprotein subunit alpha, mitochondrial (Alpha-ETF) | Mitochondrion matrix | ||
| Golgin subfamily A member 1 (Golgin-97) | Golgi apparatus membrane | ||
| Keratin, type I cytoskeletal 18 (Cell proliferation-inducing gene 46 protein) (Cytokeratin-18) (CK-18) (Keratin-18) (K18) | Cytoplasm, perinuclear region | ||
| Trafficking protein particle complex subunit 2-like protein | Cytoplasm, perinuclear region | ||
| DNA repair protein RAD51 homolog 4 (R51H3) (RAD51 homolog D) (RAD51-like protein 3) (TRAD) | Nucleus | ||
| N-alpha-acetyltransferase 10 (EC 2.3.1.255) (N-terminal acetyltransferase complex ARD1 subunit homolog A) (hARD1) (NatA catalytic subunit Naa10) | Cytoplasm | ||
| Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 (Centaurin-beta-5) (Cnt-b5) | |||
| Elongation factor Ts, mitochondrial (EF-Ts) (EF-TsMt) | Mitochondrion. | ||
| Histone PARylation factor 1 | |||
| Thioredoxin-related transmembrane protein 1 (Thioredoxin domain-containing protein 1) (Transmembrane Trx-related protein) | Membrane | ||
| Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A) | Cytoplasm | ||
| Endoplasmic reticulum resident protein 29 (ERp29) (Endoplasmic reticulum resident protein 28) (ERp28) (Endoplasmic reticulum resident protein 31) (ERp31) | |||
| 26S proteasome non-ATPase regulatory subunit 13 (26S proteasome regulatory subunit RPN9) (26S proteasome regulatory subunit S11) (26S proteasome regulatory subunit p40.5) | |||
| Platelet-activating factor acetylhydrolase IB subunit beta (EC 3.1.1.47) (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH subunit beta) (PAFAH subunit beta) | Cytoplasm. | ||
| HemK methyltransferase family member 1 (EC 2.1.1.-) (M.HsaHemKP) | Mitochondrion | ||
| Catechol O-methyltransferase (EC 2.1.1.6) | Isoform Soluble: Cytoplasm. | ||
| Sodium channel protein type 5 subunit alpha (HH1) (Sodium channel protein cardiac muscle subunit alpha) (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) | Cell membrane | ||
| Cellular retinoic acid-binding protein 1 (Cellular retinoic acid-binding protein I) (CRABP-I) | Cytoplasm | ||
| Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP) | Endoplasmic reticulum lumen | ||
| Protein NOV homolog (NovH) (CCN family member 3) (Insulin-like growth factor-binding protein 9) (IBP-9) (IGF-binding protein 9) (IGFBP-9) (Nephroblastoma-overexpressed gene protein homolog) | Secreted | ||
| Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin) | Cytoplasm | ||
| Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)] | Latency-associated peptide: Secreted, extracellular space, extracellular matrix | ||
| NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkB-B) (IkB-beta) (IkappaBbeta) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9) (TRIP-9) | Cytoplasm | ||
| Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1) | Mitochondrion matrix. | ||
| GATOR complex protein NPRL2 (Gene 21 protein) (G21 protein) (Nitrogen permease regulator 2-like protein) (NPR2-like protein) (Tumor suppressor candidate 4) | autism spectrum disorder | Lysosome membrane | |
| Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein) | Cytoplasm, perinuclear region | ||
| Leucine-rich PPR motif-containing protein, mitochondrial (130 kDa leucine-rich protein) (LRP 130) (GP130) | |||
| Zinc finger protein 135 (Zinc finger protein 61) (Zinc finger protein 78-like 1) | Nucleus | ||
| Prostaglandin E synthase 3 (EC 5.3.99.3) (Cytosolic prostaglandin E2 synthase) (cPGES) (Hsp90 co-chaperone) (Progesterone receptor complex p23) (Telomerase-binding protein p23) | Cytoplasm | ||
| Nuclear autoantigenic sperm protein (NASP) | Cytoplasm | ||
| DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD) | Cytoplasm. | ||
| Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) (EC 3.4.19.12) (EC 6.-.-.-) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1) | Parkinson disease autosomal recessive cerebellar ataxia spastic ataxia ... Lewy body dementia | Cytoplasm | |
| Zinc finger protein 423 (Olf1/EBF-associated zinc finger protein) (hOAZ) (Smad- and Olf-interacting zinc finger protein) | Nucleus | ||
| DNA-(apurinic or apyrimidinic site) lyase (EC 3.1.-.-) (EC 4.2.99.18) (APEX nuclease) (APEN) (Apurinic-apyrimidinic endonuclease 1) (AP endonuclease 1) (APE-1) (REF-1) (Redox factor-1) [Cleaved into: DNA-(apurinic or apyrimidinic site) lyase, mitochondrial] | |||
| Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1) | Isoform 1: Nucleus | ||
| Thiamine-triphosphatase (ThTPase) (EC 3.6.1.28) | Cytoplasm | ||
| Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase) | Cytoplasm. | ||
| Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1) | Cytoplasm | ||
| 28S ribosomal protein S16, mitochondrial (MRP-S16) (S16mt) (Mitochondrial small ribosomal subunit protein bS16m) | Mitochondrion | ||
| Perilipin-5 (Lipid storage droplet protein 5) | Lipid droplet | ||
| Splicing factor 3B subunit 6 (Pre-mRNA branch site protein p14) (SF3b 14 kDa subunit) (SF3B14a) (Spliceosome-associated protein, 14-kDa) (Splicing factor 3b, subunit 6, 14kDa) | Nucleus | ||
| Transcription initiation factor IIE subunit beta (TFIIE-beta) (General transcription factor IIE subunit 2) | Nucleus | ||
| Choriogonadotropin subunit beta 3 (Choriogonadotropin subunit beta) (CG-beta) (Chorionic gonadotropin chain beta) | Secreted | ||
| Glyoxalase domain-containing protein 4 | Mitochondrion | ||
| Acyl-coenzyme A thioesterase 13 (Acyl-CoA thioesterase 13) (EC 3.1.2.-) (Thioesterase superfamily member 2) [Cleaved into: Acyl-coenzyme A thioesterase 13, N-terminally processed] | Cytoplasm, cytosol | ||
| Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase subunit M1) (Ribonucleotide reductase large subunit) | Cytoplasm. | ||
| Protein canopy homolog 3 (CTG repeat protein 4a) (Expanded repeat-domain protein CAG/CTG 5) (Protein associated with TLR4) (Trinucleotide repeat-containing gene 5 protein) | Endoplasmic reticulum | ||
| Putative inactive cathepsin L-like protein CTSL3P (Cathepsin L3 pseudogene) (HCTSL-s) | |||
| Protein jagged-1 (Jagged1) (hJ1) (CD antigen CD339) | Membrane | ||
| Probable arginine--tRNA ligase, mitochondrial (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS) | pontocerebellar hypoplasia | Mitochondrion matrix | |
| Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity) | Mitochondrion inner membrane | ||
| EKC/KEOPS complex subunit TP53RK (EC 3.6.-.-) (Atypical serine/threonine protein kinase TP53RK) (Nori-2) (TP53-regulating kinase) (EC 2.7.11.1) (p53-related protein kinase) | Cytoplasm | ||
| Acylamino-acid-releasing enzyme (AARE) (EC 3.4.19.1) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) (Oxidized protein hydrolase) (OPH) | Cytoplasm. | ||
| Regulator of G-protein signaling 20 (RGS20) (Gz-selective GTPase-activating protein) (G(z)GAP) (Gz-GAP) (Regulator of G-protein signaling Z1) (Regulator of Gz-selective protein signaling 1) | |||
| Arginase-2, mitochondrial (EC 3.5.3.1) (Arginase II) (Kidney-type arginase) (Non-hepatic arginase) (Type II arginase) | Mitochondrion | ||
| Complement C1q subcomponent subunit A | Secreted. | ||
| Serum amyloid P-component (SAP) (9.5S alpha-1-glycoprotein) [Cleaved into: Serum amyloid P-component(1-203)] | Secreted. | ||
| C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2) | Cytoplasm | ||
| Histone H2A type 2-C (Histone H2A-GL101) (Histone H2A/q) | Nucleus | ||
| UPF0160 protein MYG1, mitochondrial | Nucleus | ||
| Nucleolar protein 16 (HBV pre-S2 trans-regulated protein 3) | Nucleus, nucleolus | ||
| Secretagogin | Cytoplasm | ||
| Histone deacetylase 8 (HD8) (EC 3.5.1.98) | |||
| tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (EC 2.1.1.220) (mRNA methyladenosine-N(1)-methyltransferase catalytic subunit TRMT61A) (EC 2.1.1.-) (tRNA(m1A58)-methyltransferase subunit TRMT61A) (tRNA(m1A58)MTase subunit TRMT61A) | Nucleus | ||
| Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B) | Cytoplasm | ||
| Cone-rod homeobox protein | Nucleus | ||
| Tumor protein D54 (hD54) (Tumor protein D52-like 2) | |||
| Amino-terminal enhancer of split (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) | Nucleus | ||
| Reelin (EC 3.4.21.-) | Secreted, extracellular space, extracellular matrix | ||
| Endothelial cell-specific chemotaxis regulator (Apoptosis regulator through modulating IAP expression) (ARIA) (Endothelial cell-specific molecule 2) | Cell membrane | ||
| Guanine nucleotide exchange C9orf72 | lateral sclerosis amyotrophic lateral sclerosis | Nucleus | |
| Ubiquitin-like protein ATG12 (Autophagy-related protein 12) (APG12-like) | Cytoplasm | ||
| KICSTOR complex protein SZT2 (Seizure threshold 2 protein homolog) | Lysosome membrane | ||
| Oxidative stress-induced growth inhibitor 1 (Ovary, kidney and liver protein 38) (huOKL38) (Pregnancy-induced growth inhibitor OKL38) | |||
| 5'-AMP-activated protein kinase subunit beta-2 (AMPK subunit beta-2) | |||
| Uncharacterized protein C10orf55 | |||
| Chorion-specific transcription factor GCMb (hGCMb) (GCM motif protein 2) (Glial cells missing homolog 2) | Nucleus | ||
| Calcium uptake protein 2, mitochondrial (EF-hand domain-containing family member A1) | Mitochondrion intermembrane space | ||
| Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK) | Cytoplasm, perinuclear region | ||
| Endothelin-1 receptor (Endothelin receptor type A) (ET-A) (ETA-R) (hET-AR) | Cell membrane | ||
| Carbonic anhydrase-related protein (CARP) (Carbonic anhydrase VIII) (CA-VIII) | autosomal recessive cerebellar ataxia | ||
| Unconventional myosin-X (Unconventional myosin-10) | Cytoplasm, cytosol | ||
| Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein) | Membrane, clathrin-coated pit | ||
| RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A) (Hexaribonucleotide-binding protein 1) | Nucleus | ||
| Ataxin-7 (Spinocerebellar ataxia type 7 protein) | autosomal dominant cerebellar ataxia olivopontocerebellar atrophy | ||
| Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (PRKC-lambda/iota) (aPKC-lambda/iota) (nPKC-iota) | Cytoplasm | ||
| Transcription factor Sp3 (SPR-2) | |||
| Meiosis 1 arrest protein (Meiosis 1-arresting protein) (Meiosis 1-associated protein) (Spermatogenesis-associated protein 37) | Cytoplasm | ||
| Neural retina-specific leucine zipper protein (NRL) | Cytoplasm | ||
| UBX domain-containing protein 2B (NSFL1 cofactor p37) (p97 cofactor p37) | Nucleus | ||
| Inactive pancreatic lipase-related protein 1 (PL-RP1) | Secreted | ||
| LON peptidase N-terminal domain and RING finger protein 1 (RING finger protein 191) | |||
| Transcription factor SOX-5 | lateral sclerosis | Nucleus | |
| Plasmolipin (Plasma membrane proteolipid) | Membrane | ||
| Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) | Cytoplasm, cytosol | ||
| Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes) | |||
| Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein-interacting protein 1) (Transformation-related gene 8 protein) (TRG-8) | Endoplasmic reticulum membrane | ||
| Actin, cytoplasmic 2 (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed] | Cytoplasm, cytoskeleton | ||
| Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] | Cell membrane | ||
| Solute carrier family 41 member 3 | Cell membrane | ||
| Collagen alpha-1(XVII) chain (180 kDa bullous pemphigoid antigen 2) (Bullous pemphigoid antigen 2) [Cleaved into: 120 kDa linear IgA disease antigen (120 kDa linear IgA dermatosis antigen) (Linear IgA disease antigen 1) (LAD-1); 97 kDa linear IgA disease antigen (97 kDa linear IgA bullous dermatosis antigen) (97 kDa LAD antigen) (97-LAD) (Linear IgA bullous disease antigen of 97 kDa) (LABD97)] | |||
| Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK) | Cytoplasm | ||
| Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)] | Apical cell membrane | ||
| Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148) | Cell membrane | ||
| Serine/threonine-protein phosphatase 4 regulatory subunit 1 | |||
| Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein) | autosomal dominant cerebellar ataxia | Nucleus | |
| Choline O-acetyltransferase (CHOACTase) (ChAT) (Choline acetylase) (EC 2.3.1.6) | |||
| Leucine-rich repeat and fibronectin type-III domain-containing protein 4 | Membrane | ||
| Transmembrane protein 14C | Mitochondrion membrane | ||
| Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55) | lateral sclerosis amyotrophic lateral sclerosis | Nucleus | |
| Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM-protein 2) (SLIM-2) | |||
| Cationic amino acid transporter 3 (CAT-3) (CAT3) (Cationic amino acid transporter y+) (Solute carrier family 7 member 3) | Cell membrane | ||
| Transmembrane protein 14B | Membrane | ||
| Thioredoxin domain-containing protein 15 | Membrane | ||
| Glycophorin-A (MN sialoglycoprotein) (PAS-2) (Sialoglycoprotein alpha) (CD antigen CD235a) | Cell membrane | ||
| Transmembrane protein 230 | Parkinson disease Lewy body dementia | Membrane | |
| CTD small phosphatase-like protein 2 (CTDSP-like 2) (EC 3.1.3.-) | |||
| N-terminal kinase-like protein (Coated vesicle-associated kinase of 90 kDa) (SCY1-like protein 1) (Telomerase regulation-associated protein) (Telomerase transcriptional element-interacting factor) (Teratoma-associated tyrosine kinase) | autosomal recessive cerebellar ataxia | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | |
| ATP synthase subunit epsilon, mitochondrial (ATPase subunit epsilon) (ATP synthase F1 subunit epsilon) | Mitochondrion | ||
| Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (EC 6.2.1.-) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase) | |||
| Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a) (Mediator complex subunit 15) (Positive cofactor 2 glutamine/Q-rich-associated protein) (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Trinucleotide repeat-containing gene 7 protein) | Cytoplasm | ||
| Ubiquitin-like protein 5 | Cytoplasm | ||
| Testis-specific Y-encoded protein 1 (Cancer/testis antigen 78) (CT78) | Cytoplasm | ||
| Phospholipid scramblase 3 (PL scramblase 3) (Ca(2+)-dependent phospholipid scramblase 3) | Mitochondrion membrane | ||
| FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2) | Cytoplasm, cytoskeleton | ||
| Vesicle-associated membrane protein 4 (VAMP-4) | Golgi apparatus, trans-Golgi network membrane | ||
| Cysteine-rich hydrophobic domain-containing protein 2 (BrX-like translocated in leukemia) | Cell membrane | ||
| KH domain-containing, RNA-binding, signal transduction-associated protein 2 (Sam68-like mammalian protein 1) (SLM-1) (hSLM-1) | Nucleus | ||
| Anterior gradient protein 2 homolog (AG-2) (hAG-2) (HPC8) (Secreted cement gland protein XAG-2 homolog) | Secreted | ||
| Scavenger receptor cysteine-rich type 1 protein M130 (Hemoglobin scavenger receptor) (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)] | Soluble CD163: Secreted | ||
| Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A] | Lysosome. | ||
| Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP-responsive element modulator in testis) (Activator of CREM in testis) | Nucleus | ||
| Cyclin-J-like protein | |||
| tRNA-splicing endonuclease subunit Sen54 (SEN54 homolog) (HsSEN54) (tRNA-intron endonuclease Sen54) | pontocerebellar hypoplasia | Nucleus | |
| Protein XRP2 | Cell membrane | ||
| Tumor necrosis factor receptor superfamily member 3 (Lymphotoxin-beta receptor) (Tumor necrosis factor C receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor receptor type III) (TNF-RIII) (TNFR-III) | Membrane | ||
| Nyctalopin | Secreted, extracellular space, extracellular matrix | ||
| Leukocyte-associated immunoglobulin-like receptor 2 (LAIR-2) (CD antigen CD306) | Secreted. | ||
| Vasodilator-stimulated phosphoprotein (VASP) | Cytoplasm | ||
| Small integral membrane protein 3 (NGF-induced differentiation clone 67 protein) (Small membrane protein NID67) | Membrane | ||
| Enoyl-CoA hydratase domain-containing protein 2, mitochondrial | Mitochondrion | ||
| Ubiquitin-related modifier 1 | Cytoplasm. | ||
| Bromodomain-containing protein 4 (Protein HUNK1) | |||
| Copine-4 (Copine IV) (Copine-8) | |||
| Mesothelin (CAK1 antigen) (Pre-pro-megakaryocyte-potentiating factor) [Cleaved into: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form] | Cell membrane | ||
| Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3) | Nucleus | ||
| ELL-associated factor 1 | Nucleus speckle | ||
| Histone H3.1t (H3/t) (H3t) (H3/g) | Nucleus | ||
| DNA-binding protein RFX5 (Regulatory factor X 5) | Nucleus. | ||
| AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31 protein) (Protein AF-5q31) (Major CDK9 elongation factor-associated protein) | Nucleus | ||
| Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) | Cytoplasm. | ||
| Mediator of RNA polymerase II transcription subunit 26 (Activator-recruited cofactor 70 kDa component) (ARC70) (Cofactor required for Sp1 transcriptional activation subunit 7) (CRSP complex subunit 7) (Mediator complex subunit 26) (Transcriptional coactivator CRSP70) | Nucleus | ||
| Progesterone receptor (PR) (Nuclear receptor subfamily 3 group C member 3) | |||
| AP-4 complex accessory subunit Tepsin (ENTH domain-containing protein 2) (Epsin for AP-4) (Tetra-epsin) | Golgi apparatus, trans-Golgi network membrane | ||
| CUE domain-containing protein 2 | Cytoplasm | ||
| Annexin A6 (67 kDa calelectrin) (Annexin VI) (Annexin-6) (Calphobindin-II) (CPB-II) (Chromobindin-20) (Lipocortin VI) (Protein III) (p68) (p70) | Cytoplasm | ||
| Cathepsin D (EC 3.4.23.5) [Cleaved into: Cathepsin D light chain; Cathepsin D heavy chain] | |||
| Tankyrase-2 (TANK2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (Poly [ADP-ribose] polymerase 5B) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II) (Tankyrase-like protein) (Tankyrase-related protein) | Cytoplasm | ||
| E3 ubiquitin-protein ligase RNF103 (EC 2.3.2.27) (KF-1) (hKF-1) (RING finger protein 103) (RING-type E3 ubiquitin transferase RNF103) (Zinc finger protein 103 homolog) (Zfp-103) | Endoplasmic reticulum membrane | ||
| Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4) | |||
| Minor histocompatibility antigen H13 (EC 3.4.23.-) (Intramembrane protease 1) (IMP-1) (IMPAS-1) (hIMP1) (Presenilin-like protein 3) (Signal peptide peptidase) | Endoplasmic reticulum membrane | ||
| Small VCP/p97-interacting protein | Smooth endoplasmic reticulum membrane | ||
| DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme) | Cytoplasm | ||
| Microtubule-associated protein 1S (MAP-1S) (BPY2-interacting protein 1) (Microtubule-associated protein 8) (Variable charge Y chromosome 2-interacting protein 1) (VCY2-interacting protein 1) (VCY2IP-1) [Cleaved into: MAP1S heavy chain; MAP1S light chain] | |||
| Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1) (Nucleic acid-binding protein SUB2.3) | |||
| Poly(A) polymerase gamma (PAP-gamma) (EC 2.7.7.19) (Neo-poly(A) polymerase) (Neo-PAP) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3'-adenylating enzyme) (Signal recognition particle RNA-adenylating enzyme) (SRP RNA-adenylating enzyme) | Nucleus | ||
| Suppressor of cytokine signaling 7 (SOCS-7) (Nck, Ash and phospholipase C gamma-binding protein) (Nck-associated protein 4) (NAP-4) | |||
| DNA-directed RNA polymerase II subunit RPB4 (RNA polymerase II subunit B4) (DNA-directed RNA polymerase II subunit D) (RNA polymerase II 16 kDa subunit) (RPB16) | Nucleus | ||
| Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein) | Cytoplasm | ||
| DNA damage-inducible transcript 4-like protein (HIF-1 responsive protein RTP801-like) (Protein regulated in development and DNA damage response 2) (REDD-2) | Cytoplasm | ||
| Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2) | Cytoplasm | ||
| NF-kappa-B-activating protein | Nucleus | ||
| GPN-loop GTPase 3 (ATP-binding domain 1 family member C) | |||
| Homeobox protein VENTX (VENT homeobox homolog) (VENT-like homeobox protein 2) | Nucleus | ||
| Signal-regulatory protein beta-1 isoform 3 (SIRP-beta-1 isoform 3) | Membrane | ||
| Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (Up-frameshift suppressor 3 homolog on chromosome X) (hUpf3p-X) | |||
| Keratin-associated protein 19-7 | |||
| Signal-regulatory protein beta-1 (SIRP-beta-1) (CD172 antigen-like family member B) (CD antigen CD172b) | Membrane | ||
| Protein S100-A9 (Calgranulin-B) (Calprotectin L1H subunit) (Leukocyte L1 complex heavy chain) (Migration inhibitory factor-related protein 14) (MRP-14) (p14) (S100 calcium-binding protein A9) | |||
| Plastin-3 (T-plastin) | Cytoplasm. | ||
| Vacuolar protein-sorting-associated protein 36 (ELL-associated protein of 45 kDa) (ESCRT-II complex subunit VPS36) | Cytoplasm | ||
| Glutaminase kidney isoform, mitochondrial (GLS) (EC 3.5.1.2) (K-glutaminase) (L-glutamine amidohydrolase) | Isoform 1: Cytoplasm, cytosol. | ||
| PWWP domain-containing protein MUM1 (Mutated melanoma-associated antigen 1) (MUM-1) (Protein expandere) | Nucleus | ||
| Sulfotransferase family cytosolic 2B member 1 (ST2B1) (Sulfotransferase 2B1) (EC 2.8.2.2) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2) | Cytoplasm | ||
| Thymidine phosphorylase (TP) (EC 2.4.2.4) (Gliostatin) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (TdRPase) | |||
| Keratin, type II cytoskeletal 3 (65 kDa cytokeratin) (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (Type-II keratin Kb3) | |||
| Kallikrein-8 (hK8) (EC 3.4.21.118) (Neuropsin) (NP) (Ovasin) (Serine protease 19) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein) | Secreted | ||
| Oncostatin-M-specific receptor subunit beta (Interleukin-31 receptor subunit beta) (IL-31 receptor subunit beta) (IL-31R subunit beta) (IL-31R-beta) (IL-31RB) | Membrane | ||
| Aromatic-L-amino-acid decarboxylase (AADC) (EC 4.1.1.28) (DOPA decarboxylase) (DDC) | |||
| Protein S100-A7 (Psoriasin) (S100 calcium-binding protein A7) | Cytoplasm | ||
| DNA-directed RNA polymerase II subunit RPB9 (RNA polymerase II subunit B9) (DNA-directed RNA polymerase II subunit I) (RNA polymerase II 14.5 kDa subunit) (RPB14.5) | Nucleus, nucleolus | ||
| Large subunit GTPase 1 homolog (hLsg1) (EC 3.6.1.-) | Cytoplasm | ||
| GATOR complex protein DEPDC5 (DEP domain-containing protein 5) | autism spectrum disorder | Cytoplasm, cytosol | |
| GATOR complex protein NPRL3 (-14 gene protein) (Alpha-globin regulatory element-containing gene protein) (Nitrogen permease regulator 3-like protein) (Protein CGTHBA) | autism spectrum disorder | Lysosome membrane | |
| Pulmonary surfactant-associated protein C (SP-C) (Pulmonary surfactant-associated proteolipid SPL(Val)) (SP5) | Secreted, extracellular space, surface film. | ||
| Desumoylating isopeptidase 1 (DeSI-1) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 2) (Protein FAM152B) | Cytoplasm | ||
| Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) (Kidney amine oxidase) (KAO) | Secreted, extracellular space. | ||
| Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198) | Cytoplasm, P-body | ||
| Pulmonary surfactant-associated protein A2 (PSP-A) (PSPA) (SP-A) (SP-A2) (35 kDa pulmonary surfactant-associated protein) (Alveolar proteinosis protein) (Collectin-5) | Secreted, extracellular space, extracellular matrix | ||
| Surfeit locus protein 2 (Surf-2) | |||
| 3 beta-hydroxysteroid dehydrogenase type 7 (3 beta-hydroxysteroid dehydrogenase type VII) (3-beta-HSD VII) (3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase) (C(27) 3-beta-HSD) (EC 1.1.1.-) (Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase) (EC 1.1.1.181) | Endoplasmic reticulum membrane | ||
| Kinesin-like protein KIF11 (Kinesin-like protein 1) (Kinesin-like spindle protein HKSP) (Kinesin-related motor protein Eg5) (Thyroid receptor-interacting protein 5) (TR-interacting protein 5) (TRIP-5) | Cytoplasm | ||
| Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer-related gene-coding leucine-zipper motif) (Fez1) | Cytoplasm | ||
| Fanconi anemia group G protein (Protein FACG) (DNA repair protein XRCC9) | Nucleus | ||
| 5-azacytidine-induced protein 2 (NF-kappa-B-activating kinase-associated protein 1) (Nak-associated protein 1) (TILP) | Cytoplasm | ||
| Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9) | Endoplasmic reticulum membrane | ||
| Polynucleotide 5'-hydroxyl-kinase NOL9 (EC 2.7.1.-) (Nucleolar protein 9) | Nucleus | ||
| Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1] | Nucleus. | ||
| Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI) | Parkinson disease | Mitochondrion intermembrane space | |
| Ubiquitin carboxyl-terminal hydrolase 45 (EC 3.4.19.12) (Deubiquitinating enzyme 45) (Ubiquitin thioesterase 45) (Ubiquitin-specific-processing protease 45) | |||
| Netrin receptor UNC5C (Protein unc-5 homolog 3) (Protein unc-5 homolog C) | Alzheimer disease | Cell membrane | |
| von Willebrand factor A domain-containing protein 3B (VWA domain-containing protein 3B) | autosomal recessive cerebellar ataxia | Cytoplasm | |
| Cysteine-rich and transmembrane domain-containing protein 1 | Membrane | ||
| Hamartin (Tuberous sclerosis 1 protein) | Cytoplasm | ||
| Epimerase family protein SDR39U1 (EC 1.1.1.-) (Short-chain dehydrogenase/reductase family 39U member 1) | |||
| Dynactin subunit 6 (Dynactin subunit p27) (Protein WS-3) | Cytoplasm, cytoskeleton | ||
| Guanylate kinase (EC 2.7.4.8) (GMP kinase) | |||
| Melanoma-associated antigen 4 (Cancer/testis antigen 1.4) (CT1.4) (MAGE-4 antigen) (MAGE-41 antigen) (MAGE-X2 antigen) | autism spectrum disorder | ||
| High mobility group protein B1 (High mobility group protein 1) (HMG-1) | Nucleus | ||
| G1/S-specific cyclin-D3 | Nucleus | ||
| Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) (PAK-6) | |||
| Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6) | Nucleus | ||
| Epsin-1 (EH domain-binding mitotic phosphoprotein) (EPS-15-interacting protein 1) | Cytoplasm | ||
| Succinate dehydrogenase assembly factor 3, mitochondrial (SDH assembly factor 3) (SDHAF3) | Mitochondrion matrix | ||
| Succinate dehydrogenase assembly factor 4, mitochondrial (SDH assembly factor 4) (SDHAF4) | Mitochondrion matrix | ||
| Inactive serine protease 35 | Secreted | ||
| Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial (EC 2.8.3.5) (3-oxoacid CoA-transferase 2A) (Testis-specific succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-t) | Mitochondrion | ||
| Phosphatidate cytidylyltransferase, mitochondrial (EC 2.7.7.41) (CDP-diacylglycerol synthase) (CDP-DAG synthase) (Mitochondrial translocator assembly and maintenance protein 41 homolog) (TAM41) | Mitochondrion inner membrane | ||
| 4-hydroxy-2-oxoglutarate aldolase, mitochondrial (EC 4.1.3.16) (Dihydrodipicolinate synthase-like) (DHDPS-like protein) (Probable 2-keto-4-hydroxyglutarate aldolase) (Probable KHG-aldolase) (Protein 569272) | Mitochondrion | ||
| Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein) | multiple sclerosis | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 (Hormone-regulated proliferation-associated protein of 20 kDa) | Parkinson disease | Mitochondrion | |
| Haloacid dehalogenase-like hydrolase domain-containing 5 (Cat eye syndrome critical region protein 5) | |||
| Testis-specific Y-encoded-like protein 2 (TSPY-like protein 2) (Cell division autoantigen 1) (Cutaneous T-cell lymphoma-associated antigen se20-4) (CTCL-associated antigen se20-4) (Differentially-expressed nucleolar TGF-beta1 target protein) (Nuclear protein of 79 kDa) (NP79) | Nucleus | ||
| RalBP1-associated Eps domain-containing protein 2 (Partner of RalBP1) (RalBP1-interacting protein 2) | Cytoplasm. | ||
| Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (VLCAD) (EC 1.3.8.9) | Mitochondrion inner membrane. | ||
| Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller) | Nucleus speckle | ||
| Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like) | autosomal dominant cerebellar ataxia | Early endosome | |
| Lymphokine-activated killer T-cell-originated protein kinase (EC 2.7.12.2) (Cancer/testis antigen 84) (CT84) (MAPKK-like protein kinase) (Nori-3) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (T-LAK cell-originated protein kinase) | |||
| Target of Myb protein 1 | Cytoplasm | ||
| Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI) | Cytoplasm | ||
| Histone H1.3 (Histone H1c) (Histone H1s-2) | |||
| Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap) | Nucleus, nucleolus | ||
| Integrin beta-7 (Gut homing receptor beta subunit) | Membrane | ||
| Apoptosis regulator Bcl-2 | Mitochondrion outer membrane | ||
| Membrane-associated phosphatidylinositol transfer protein 1 (Drosophila retinal degeneration B homolog) (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) | Cytoplasm | ||
| Magnesium transporter protein 1 (MagT1) (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1) (Oligosaccharyl transferase subunit MAGT1) (Implantation-associated protein) (IAP) | Cell membrane | ||
| Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13) | Cytoplasm | ||
| Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (Ubiquitin thioesterase 16) (Ubiquitin-processing protease UBP-M) (Ubiquitin-specific-processing protease 16) | Nucleus | ||
| EF-hand calcium-binding domain-containing protein 6 (CAP-binding protein complex-interacting protein 1) (DJ-1-binding protein) (DJBP) | Nucleus | ||
| Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit) | Nucleus. | ||
| Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (DNase IV) (Flap structure-specific endonuclease 1) (Maturation factor 1) (MF1) (hFEN-1) | |||
| Follistatin-related protein 3 (Follistatin-like protein 3) (Follistatin-related gene protein) | Isoform 1: Secreted. | ||
| G2/mitotic-specific cyclin-B2 | |||
| N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37) | Nucleus. | ||
| Nuclear distribution protein nudE homolog 1 (NudE) | |||
| GDNF family receptor alpha-1 (GDNF receptor alpha-1) (GDNFR-alpha-1) (GFR-alpha-1) (RET ligand 1) (TGF-beta-related neurotrophic factor receptor 1) | Cell membrane | ||
| GDNF family receptor alpha-2 (GDNF receptor alpha-2) (GDNFR-alpha-2) (GFR-alpha-2) (GDNF receptor beta) (GDNFR-beta) (Neurturin receptor alpha) (NRTNR-alpha) (NTNR-alpha) (RET ligand 2) (TGF-beta-related neurotrophic factor receptor 2) | Cell membrane | ||
| Thrombospondin-3 | |||
| Multimerin-1 (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4) (Endothelial cell multimerin) [Cleaved into: Platelet glycoprotein Ia*; 155 kDa platelet multimerin (p-155) (p155)] | Secreted | ||
| Kallikrein-7 (hK7) (EC 3.4.21.117) (Serine protease 6) (Stratum corneum chymotryptic enzyme) (hSCCE) | Secreted | ||
| Coiled-coil domain-containing protein 51 | Membrane | ||
| Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-DAG synthase 1) (CDP-DG synthase 1) (CDP-diacylglycerol synthase 1) (CDS 1) (CDP-diglyceride pyrophosphorylase 1) (CDP-diglyceride synthase 1) (CTP:phosphatidate cytidylyltransferase 1) | Endoplasmic reticulum membrane | ||
| Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase) | Mitochondrion inner membrane | ||
| Peroxisomal membrane protein 11A (HsPEX11p) (28 kDa peroxisomal integral membrane protein) (PMP28) (Peroxin-11A) (Peroxisomal biogenesis factor 11A) (Protein PEX11 homolog alpha) (PEX11-alpha) | Peroxisome membrane | ||
| Peroxisomal membrane protein 11C (Peroxin-11C) (Peroxisomal biogenesis factor 11C) (Protein PEX11 homolog gamma) (PEX11-gamma) | Peroxisome membrane | ||
| Spindle and centriole-associated protein 1 (Coiled-coil domain-containing protein 52) (Spindle and centriole-associated protein) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Pyrin domain-containing protein 1 (PAAD-only protein 1) (Pyrin-only protein 1) (cellular POP1) (cPOP1) | Cytoplasm | ||
| Exocyst complex component 1 (Exocyst complex component Sec3) | Midbody, Midbody ring | ||
| Protocadherin gamma-A9 (PCDH-gamma-A9) | Cell membrane | ||
| Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Bucelipase) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase) | Secreted. | ||
| Fibrinogen-like protein 1 (HP-041) (Hepassocin) (Hepatocyte-derived fibrinogen-related protein 1) (HFREP-1) (Liver fibrinogen-related protein 1) (LFIRE-1) | Secreted. | ||
| Nucleolar transcription factor 1 (Autoantigen NOR-90) (Upstream-binding factor 1) (UBF-1) | Nucleus, nucleolus | ||
| RNA polymerase II-associated protein 1 | Nucleus | ||
| Kinesin light chain 3 (KLC2-like) (kinesin light chain 2) | Cytoplasm, cytoskeleton | ||
| NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Renal carcinoma antigen NY-REN-18) | Nucleus | ||
| RNA-binding protein Raly (Autoantigen p542) (Heterogeneous nuclear ribonucleoprotein C-like 2) (hnRNP core protein C-like 2) (hnRNP associated with lethal yellow protein homolog) | Nucleus | ||
| AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216) | Cytoplasm | ||
| Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein) | Cytoplasm | ||
| Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) | Cytoplasm | ||
| Kinesin-like protein KIF2A (Kinesin-2) (hK2) | Cytoplasm | ||
| Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-) | |||
| Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4) | Cell membrane | ||
| Intraflagellar transport protein 57 homolog (Dermal papilla-derived protein 8) (Estrogen-related receptor beta-like protein 1) (HIP1-interacting protein) (MHS4R2) | Cytoplasm, cytoskeleton, cilium basal body | ||
| Integrin alpha-1 (CD49 antigen-like family member A) (Laminin and collagen receptor) (VLA-1) (CD antigen CD49a) | Membrane | ||
| Sodium channel and clathrin linker 1 (Sodium channel-associated protein 1) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole | ||
| Coiled-coil domain-containing protein 151 | Cell projection, cilium | ||
| Probable E3 ubiquitin-protein ligase MID2 (EC 2.3.2.27) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (RING-type E3 ubiquitin transferase MID2) (Tripartite motif-containing protein 1) | |||
| Fc receptor-like protein 3 (FcR-like protein 3) (FcRL3) (Fc receptor homolog 3) (FcRH3) (IFGP family protein 3) (hIFGP3) (Immune receptor translocation-associated protein 3) (SH2 domain-containing phosphatase anchor protein 2) (CD antigen CD307c) | multiple sclerosis | Cell membrane | |
| Pre-mRNA-splicing regulator WTAP (Female-lethal(2)D homolog) (hFL(2)D) (WT1-associated protein) (Wilms tumor 1-associating protein) | Nucleus speckle | ||
| Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36) | Nucleus | ||
| Protein BHLHb9 (bHLHb9) (Transcription regulator of 60 kDa) (p60TRP) | Cytoplasm | ||
| Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) | Cell membrane | ||
| Carbohydrate sulfotransferase 12 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 2) (Chondroitin 4-sulfotransferase 2) (C4ST-2) (C4ST2) (Sulfotransferase Hlo) | Golgi apparatus membrane | ||
| NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein) | Pick disease | Late endosome membrane | |
| Phosphoglycerate kinase 1 (EC 2.7.2.3) (Cell migration-inducing gene 10 protein) (Primer recognition protein 2) (PRP 2) | Cytoplasm. | ||
| ATP synthase subunit d, mitochondrial (ATPase subunit d) (ATP synthase peripheral stalk subunit d) | Mitochondrion | ||
| Histone H3.3 | Nucleus | ||
| Ras-related protein Rab-20 | Golgi apparatus | ||
| Histone H2A type 1-D (Histone H2A.3) (Histone H2A/g) | Nucleus | ||
| Ras-related protein Rab-3C | Cell membrane | ||
| E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein) | Nucleus | ||
| 39S ribosomal protein L3, mitochondrial (L3mt) (MRP-L3) (Mitochondrial large ribosomal subunit protein uL3m) | Mitochondrion | ||
| CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4) | Nucleus | ||
| Sodium channel protein type 3 subunit alpha (Sodium channel protein brain III subunit alpha) (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subtype III) (Voltage-gated sodium channel subunit alpha Nav1.3) | autism spectrum disorder | Cell membrane | |
| Zinc finger MIZ domain-containing protein 2 (PIAS-like protein Zimp7) | Nucleus | ||
| Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3) | Cytoplasm, cytoskeleton | ||
| NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (EC 1.6.99.3) (EC 7.1.1.2) (NADH-ubiquinone oxidoreductase 24 kDa subunit) | Parkinson disease | Mitochondrion inner membrane. | |
| Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1) | Cytoplasm | ||
| Protein SPT2 homolog (Protein KU002155) (SPT2 domain-containing protein 1) | Nucleus, nucleolus | ||
| Plexin-B2 (MM1) | Cell membrane | ||
| Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein) | autism spectrum disorder | ||
| Methyltransferase-like protein 2B (EC 2.1.1.-) | |||
| Signal-induced proliferation-associated 1-like protein 1 (SIPA1-like protein 1) (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6-targeted protein 1) | Cytoplasm, cytoskeleton | ||
| MIT domain-containing protein 1 | |||
| Small G protein signaling modulator 3 (Merlin-associated protein) (RUN and TBC1 domain-containing protein 3) (Rab-GTPase-activating protein-like protein) (RabGAPLP) | Cytoplasm | ||
| tRNA-splicing endonuclease subunit Sen2 (EC 4.6.1.16) (tRNA-intron endonuclease Sen2) (HsSen2) | pontocerebellar hypoplasia | Nucleus | |
| Reticulophagy regulator 3 | Membrane | ||
| ATP synthase F(0) complex subunit B1, mitochondrial (ATP synthase peripheral stalk-membrane subunit b) (ATP synthase proton-transporting mitochondrial F(0) complex subunit B1) (ATP synthase subunit b) (ATPase subunit b) | Mitochondrion | ||
| Plasminogen activator inhibitor 2 (PAI-2) (Monocyte Arg-serpin) (Placental plasminogen activator inhibitor) (Serpin B2) (Urokinase inhibitor) | Cytoplasm | ||
| Protein POF1B (Premature ovarian failure protein 1B) | Cell junction, tight junction | ||
| Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3) [Cleaved into: Ganglioside GM2 activator isoform short] | Lysosome. | ||
| Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4) | Cytoplasm, cytoskeleton | ||
| Heat shock protein beta-3 (HspB3) (Heat shock 17 kDa protein) (HSP 17) (Protein 3) | spinal muscular atrophy | Cytoplasm | |
| Protein flightless-1 homolog | Nucleus | ||
| Tumor suppressor ARF (Alternative reading frame) (ARF) (Cyclin-dependent kinase inhibitor 2A) (p14ARF) | Nucleus, nucleolus | ||
| Hairy/enhancer-of-split related with YRPW motif-like protein (hHeyL) (Class B basic helix-loop-helix protein 33) (bHLHb33) (Hairy-related transcription factor 3) (HRT-3) (hHRT3) | Nucleus | ||
| Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Keratin-associated protein 23-1 | |||
| T-box transcription factor TBX6 (T-box protein 6) | Nucleus | ||
| AP-2 complex subunit alpha-1 (100 kDa coated vesicle protein A) (Adaptor protein complex AP-2 subunit alpha-1) (Adaptor-related protein complex 2 subunit alpha-1) (Alpha-adaptin A) (Alpha1-adaptin) (Clathrin assembly protein complex 2 alpha-A large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit) | Cell membrane | ||
| Supervillin (Archvillin) (p205/p250) | Cell membrane | ||
| Caveolae-associated protein 3 (Cavin-3) (Protein kinase C delta-binding protein) (Serum deprivation response factor-related gene product that binds to C-kinase) (hSRBC) | Cytoplasm | ||
| ADP/ATP translocase 1 (ADP,ATP carrier protein 1) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) (Adenine nucleotide translocator 1) (ANT 1) (Solute carrier family 25 member 4) | Mitochondrion inner membrane | ||
| Anaphase-promoting complex subunit 15 (APC15) | |||
| CREB-regulated transcription coactivator 3 (Transducer of regulated cAMP response element-binding protein 3) (TORC-3) (Transducer of CREB protein 3) | Nucleus | ||
| Single-strand selective monofunctional uracil DNA glycosylase (EC 3.2.2.-) | Nucleus | ||
| Complement decay-accelerating factor (CD antigen CD55) | Isoform 1: Cell membrane | ||
| Growth hormone-inducible transmembrane protein (Dermal papilla-derived protein 2) (Mitochondrial morphology and cristae structure 1) (MICS1) (Transmembrane BAX inhibitor motif-containing protein 5) | Mitochondrion inner membrane | ||
| Mitochondrial carrier homolog 2 (Met-induced mitochondrial protein) | Mitochondrion inner membrane | ||
| Acyl-coenzyme A thioesterase 2, mitochondrial (Acyl-CoA thioesterase 2) (EC 3.1.2.2) (Acyl-coenzyme A thioester hydrolase 2a) (CTE-Ia) (Long-chain acyl-CoA thioesterase 2) (ZAP128) | Mitochondrion | ||
| Up-regulated during skeletal muscle growth protein 5 (ATP synthase membrane subunit DAPIT) (Diabetes-associated protein in insulin-sensitive tissues) (HCV F-transactivated protein 2) | Mitochondrion membrane | ||
| Ribonuclease H1 (RNase H1) (EC 3.1.26.4) (Ribonuclease H type II) | Cytoplasm | ||
| 39S ribosomal protein L23, mitochondrial (L23mt) (MRP-L23) (L23 mitochondrial-related protein) (Mitochondrial large ribosomal subunit protein uL23m) (Ribosomal protein L23-like) | Mitochondrion | ||
| Mitochondrial inner membrane protein OXA1L (Hsa) (OXA1Hs) (Oxidase assembly 1-like protein) (OXA1-like protein) | Mitochondrion inner membrane | ||
| COMM domain-containing protein 10 | Cytoplasm | ||
| Glutaredoxin-related protein 5, mitochondrial (Monothiol glutaredoxin-5) | Mitochondrion matrix | ||
| COMM domain-containing protein 5 (Hypertension-related calcium-regulated gene protein) (HCaRG) | Cytoplasm | ||
| EF-hand domain-containing protein D1 (EF-hand domain-containing protein 1) (Swiprosin-2) | Mitochondrion inner membrane | ||
| Mitochondrial import inner membrane translocase subunit TIM44 | Mitochondrion inner membrane | ||
| COMM domain-containing protein 9 | Nucleus | ||
| StAR-related lipid transfer protein 7, mitochondrial (Gestational trophoblastic tumor protein 1) (START domain-containing protein 7) (StARD7) | Mitochondrion | ||
| ATP synthase subunit O, mitochondrial (ATP synthase peripheral stalk subunit OSCP) (Oligomycin sensitivity conferral protein) (OSCP) | Mitochondrion | ||
| Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein) | Mitochondrion inner membrane | ||
| Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) | Mitochondrion matrix | ||
| 1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) | Endosome membrane | ||
| Neprilysin (EC 3.4.24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10) | autosomal dominant cerebellar ataxia | Cell membrane | |
| Mediator of RNA polymerase II transcription subunit 19 (Lung cancer metastasis-related protein 1) (Mediator complex subunit 19) | Nucleus | ||
| Ras GTPase-activating protein 2 (GTPase-activating protein 1m) (GAP1m) | Cytoplasm | ||
| Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363) | |||
| Transcription termination factor 3, mitochondrial (Mitochondrial transcription termination factor 3) (mTERF3) (mTERF domain-containing protein 1, mitochondrial) | Mitochondrion | ||
| Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6) (Protein kinase SID6-1512) | |||
| Ribosomal RNA-processing protein 7 homolog A (Gastric cancer antigen Zg14) | |||
| Calpain-3 (EC 3.4.22.54) (Calcium-activated neutral proteinase 3) (CANP 3) (Calpain L3) (Calpain p94) (Muscle-specific calcium-activated neutral protease 3) (New calpain 1) (nCL-1) | progressive muscular atrophy | Cytoplasm. | |
| Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89) | |||
| SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin-3-interacting protein) | Membrane, clathrin-coated pit | ||
| CAP-Gly domain-containing linker protein 4 (Restin-like protein 2) | |||
| Zinc finger protein 576 | Nucleus | ||
| HLA class II histocompatibility antigen, DRB1-15 beta chain (DW2.2/DR2.2) (MHC class II antigen DRB1*15) | Cell membrane | ||
| Ras-related protein Rab-39B | Parkinson disease autism spectrum disorder | Cell membrane | |
| Branched-chain-amino-acid aminotransferase, cytosolic (BCAT(c)) (EC 2.6.1.42) (Protein ECA39) | Cytoplasm. | ||
| 39S ribosomal protein L55, mitochondrial (L55mt) (MRP-L55) (Mitochondrial large ribosomal subunit protein bL31m) (Mitochondrial large ribosomal subunit protein mL55) | Mitochondrion | ||
| 39S ribosomal protein S18a, mitochondrial (MRP-S18-a) (Mrps18a) (S18mt-a) (39S ribosomal protein S18-3, mitochondrial) (MRP-S18-3) (Mitochondrial large ribosomal subunit protein bS18a) (Mitochondrial large ribosomal subunit protein mL66) | Mitochondrion | ||
| Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2) | Cytoplasm | ||
| Ras-related protein Ral-A | Cell membrane | ||
| Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (OTU domain-containing protein 7C) (Putative DNA-binding protein A20) (Zinc finger protein A20) [Cleaved into: A20p50; A20p37] | Cytoplasm | ||
| RNA-binding protein 27 (RNA-binding motif protein 27) | |||
| TNFAIP3-interacting protein 3 (A20-binding inhibitor of NF-kappa-B activation 3) (ABIN-3) (Listeria-induced gene protein) | |||
| Keratin-associated protein 2-3 (High sulfur keratin-associated protein 2.4) (Keratin-associated protein 2.3) | |||
| Troponin I, cardiac muscle (Cardiac troponin I) | |||
| Metal transporter CNNM3 (Ancient conserved domain-containing protein 3) (Cyclin-M3) | Cell membrane | ||
| Nucleoside diphosphate kinase 6 (NDK 6) (NDP kinase 6) (EC 2.7.4.6) (Inhibitor of p53-induced apoptosis-alpha) (IPIA-alpha) (nm23-H6) | |||
| RB-associated KRAB zinc finger protein (RB-associated KRAB repressor) (hRBaK) (Zinc finger protein 769) | Nucleus | ||
| Keratin-associated protein 2-4 (High sulfur keratin-associated protein 2.4) (Keratin-associated protein 2.4) | |||
| Stimulator of interferon genes protein (hSTING) (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (hMITA) (Transmembrane protein 173) | Endoplasmic reticulum membrane | ||
| Septin-4 (Apoptosis-related protein in the TGF-beta signaling pathway) (ARTS) (Bradeion beta) (Brain protein H5) (CE5B3 beta) (Cell division control-related protein 2) (hCDCREL-2) (Cerebral protein 7) (Peanut-like protein 2) | Cytoplasm | ||
| Keratin-associated protein 3-2 (High sulfur keratin-associated protein 3.2) (Keratin-associated protein 3.2) | |||
| Ubiquitin-conjugating enzyme E2 G2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G2) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2) | |||
| Paired box protein Pax-2 | Nucleus. | ||
| Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) | Nucleus | ||
| Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin) | |||
| Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase) | |||
| OTU domain-containing protein 1 (EC 3.4.19.12) (DUBA-7) | |||
| Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] | Cell membrane | ||
| Retinoic acid receptor RXR-alpha (Nuclear receptor subfamily 2 group B member 1) (Retinoid X receptor alpha) | Nucleus | ||
| Prolactin-releasing peptide receptor (PrRP receptor) (PrRPR) (G-protein coupled receptor 10) (hGR3) | Cell membrane | ||
| Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf-HX) | |||
| Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) | Cytoplasm | ||
| Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) | infantile cerebellar-retinal degeneration | Mitochondrion | |
| Integrin alpha-2 (CD49 antigen-like family member B) (Collagen receptor) (Platelet membrane glycoprotein Ia) (GPIa) (VLA-2 subunit alpha) (CD antigen CD49b) | Membrane | ||
| E3 ubiquitin-protein ligase MYLIP (EC 2.3.2.27) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR) (RING-type E3 ubiquitin transferase MYLIP) | Cytoplasm | ||
| ADP-ribosylation factor-like protein 8A (ADP-ribosylation factor-like protein 10B) (Novel small G protein indispensable for equal chromosome segregation 2) | Late endosome membrane | ||
| Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor) | Nucleus. | ||
| Voltage-dependent calcium channel subunit alpha-2/delta-1 (Voltage-gated calcium channel subunit alpha-2/delta-1) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-1; Voltage-dependent calcium channel subunit delta-1] | Membrane | ||
| Carbohydrate sulfotransferase 14 (EC 2.8.2.35) (Dermatan 4-sulfotransferase 1) (D4ST-1) (hD4ST1) | Golgi apparatus membrane | ||
| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (60 kDa BRG-1/Brm-associated factor subunit A) (BRG1-associated factor 60A) (BAF60A) (SWI/SNF complex 60 kDa subunit) | Nucleus | ||
| Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST-2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)] | Golgi apparatus membrane | ||
| Syntabulin (Golgi-localized syntaphilin-related protein) (Syntaxin-1-binding protein) | |||
| Protein BRICK1 (BRK1) | Cytoplasm, cytoskeleton | ||
| Olfactory receptor 4S2 (Olfactory receptor OR11-137) | Cell membrane | ||
| BLOC-1-related complex subunit 6 (Lysosome-dispersing protein) (Lyspersin) | Lysosome membrane | ||
| ABI gene family member 3 (New molecule including SH3) (Nesh) | Cytoplasm | ||
| Nck-associated protein 1 (NAP 1) (Membrane-associated protein HEM-2) (p125Nap1) | Cell membrane | ||
| Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121) | Cytoplasm | ||
| MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAP-K5) (MAPKAPK-5) (MK-5) (MK5) (EC 2.7.11.1) (p38-regulated/activated protein kinase) (PRAK) | |||
| AP-3 complex subunit beta-1 (Adaptor protein complex AP-3 subunit beta-1) (Adaptor-related protein complex 3 subunit beta-1) (Beta-3A-adaptin) (Clathrin assembly protein complex 3 beta-1 large chain) | Cytoplasmic vesicle, clathrin-coated vesicle membrane | ||
| Transient receptor potential cation channel subfamily V member 4 (TrpV4) (Osm-9-like TRP channel 4) (OTRPC4) (Transient receptor potential protein 12) (TRP12) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) | progressive muscular atrophy spinal muscular atrophy | Apical cell membrane | |
| Dystrobrevin beta (DTN-B) (Beta-dystrobrevin) | Cytoplasm. | ||
| Plasminogen activator inhibitor 1 (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1) | Secreted | ||
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1) | |||
| Vacuolar protein sorting-associated protein 53 homolog | pontocerebellar hypoplasia | Golgi apparatus, trans-Golgi network membrane | |
| Insulin-like growth factor-binding protein 5 (IBP-5) (IGF-binding protein 5) (IGFBP-5) | Secreted. | ||
| Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) | Mitochondrion matrix. | ||
| Kinesin-like protein KIFC3 | Cell junction, adherens junction | ||
| Ras-related protein Rab-11A (Rab-11) (YL8) | Cell membrane | ||
| Toll-like receptor 9 (CD antigen CD289) | Endoplasmic reticulum membrane | ||
| Dystrobrevin alpha (DTN-A) (Alpha-dystrobrevin) (Dystrophin-related protein 3) | Cytoplasm | ||
| High affinity choline transporter 1 (Hemicholinium-3-sensitive choline transporter) (CHT) (Solute carrier family 5 member 7) | progressive muscular atrophy | Membrane | |
| Kinesin light chain 1 (KLC 1) | Cell projection, growth cone | ||
| Kinesin heavy chain isoform 5A (Kinesin heavy chain neuron-specific 1) (Neuronal kinesin heavy chain) (NKHC) | lateral sclerosis amyotrophic lateral sclerosis | Cytoplasm, perinuclear region | |
| Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1) | Cytoplasm | ||
| Villin-1 | Cytoplasm, cytoskeleton | ||
| Adenylosuccinate synthetase isozyme 1 (AMPSase 1) (AdSS 1) (EC 6.3.4.4) (Adenylosuccinate synthetase, basic isozyme) (Adenylosuccinate synthetase, muscle isozyme) (M-type adenylosuccinate synthetase) (IMP--aspartate ligase 1) | progressive muscular atrophy | Cytoplasm | |
| Vacuolar protein sorting-associated protein 51 homolog (Another new gene 2 protein) (Protein fat-free homolog) | Golgi apparatus, trans-Golgi network | ||
| Neurotrophin-3 (NT-3) (HDNF) (Nerve growth factor 2) (NGF-2) (Neurotrophic factor) | Secreted. | ||
| WASH complex subunit 3 (Coiled-coil domain-containing protein 53) | Early endosome | ||
| Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta] | progressive muscular atrophy | Lysosome. | |
| Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B-related factor 1) (BRF-1) (hBRF) (TAF3B2) (TATA box-binding protein-associated factor, RNA polymerase III, subunit 2) | Nucleus | ||
| Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1) | Cytoplasm | ||
| Oxysterol-binding protein-related protein 9 (ORP-9) (OSBP-related protein 9) | Late endosome membrane | ||
| EARP and GARP complex-interacting protein 1 (Endosome-associated recycling protein-interacting protein) (Golgi-associated retrograde protein-interacting protein) (Tumor-suppressing STF cDNA 1 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein) | Golgi apparatus, trans-Golgi network | ||
| Ribosome production factor 1 (Brix domain-containing protein 5) (Ribosome biogenesis protein RPF1) | Nucleus, nucleolus | ||
| Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1) | Alzheimer disease | Cytoplasm | |
| Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC) | Cytoplasm, cytoskeleton | ||
| Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myosin-12) (Myoxin) | |||
| BRCA1-associated ATM activator 1 (BRCA1-associated protein required for ATM activation protein 1) | autosomal recessive cerebellar ataxia | Nucleus | |
| Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) (ADP-ribosylation factor guanine nucleotide-exchange factor 2) | Cytoplasm | ||
| Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1) | Early endosome membrane | ||
| AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Clathrin-associated/assembly/adaptor protein, small 3) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a) | |||
| HAUS augmin-like complex subunit 1 (Coiled-coil domain-containing protein 5) (Enhancer of invasion-cluster) (HEI-C) | Cytoplasm | ||
| BRD4-interacting chromatin-remodeling complex-associated protein-like (Glioma tumor suppressor candidate region gene 1 protein-like) | |||
| Prolyl 4-hydroxylase subunit alpha-3 (4-PH alpha-3) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3) | Endoplasmic reticulum lumen | ||
| Kinesin light chain 2 (KLC 2) | Cytoplasm, cytoskeleton | ||
| Laforin (EC 3.1.3.-) (EC 3.1.3.16) (EC 3.1.3.48) (Glucan phosphatase) (Glycogen phosphatase) (Lafora PTPase) (LAFPTPase) | Lafora disease | Cytoplasm | |
| Eosinophil peroxidase (EPO) (EC 1.11.1.7) [Cleaved into: Eosinophil peroxidase light chain; Eosinophil peroxidase heavy chain] | |||
| Exosome complex component RRP43 (Exosome component 8) (Opa-interacting protein 2) (OIP-2) (Ribosomal RNA-processing protein 43) (p9) | pontocerebellar hypoplasia | Cytoplasm | |
| Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (Cytochrome P450 form 6) (Cytochrome P450-C) (Cytochrome P450-P1) | Endoplasmic reticulum membrane | ||
| Cytochrome c oxidase subunit 8A, mitochondrial (Cytochrome c oxidase polypeptide VIII-liver/heart) (Cytochrome c oxidase subunit 8-2) | Mitochondrion inner membrane. | ||
| Uncharacterized protein C6orf132 | |||
| UPF0505 protein C16orf62 (Esophageal cancer-associated protein) | Membrane | ||
| COMM domain-containing protein 3 (Protein Bup) (Protein PIL) | Cytoplasm | ||
| COMM domain-containing protein 4 | Cytoplasm | ||
| Coiled-coil domain-containing protein 93 | Early endosome | ||
| rRNA-processing protein UTP23 homolog | Nucleus, nucleolus | ||
| Cholesterol side-chain cleavage enzyme, mitochondrial (EC 1.14.15.6) (CYPXIA1) (Cholesterol desmolase) (Cytochrome P450 11A1) (Cytochrome P450(scc)) | Mitochondrion inner membrane | ||
| PR domain zinc finger protein 15 (EC 2.1.1.-) (PR domain-containing protein 15) (Zinc finger protein 298) | Nucleus | ||
| CCAAT/enhancer-binding protein beta (C/EBP beta) (Liver activator protein) (LAP) (Liver-enriched inhibitory protein) (LIP) (Nuclear factor NF-IL6) (Transcription factor 5) (TCF-5) | Nucleus | ||
| Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit) | Cytoplasm | ||
| Golgi to ER traffic protein 4 homolog (Conserved edge-expressed protein) (Transmembrane domain recognition complex 35 kDa subunit) (TRC35) | Cytoplasm, cytosol | ||
| Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132) | Membrane | ||
| Calpain-2 catalytic subunit (EC 3.4.22.53) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain large polypeptide L2) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain) | |||
| Receptor-type tyrosine-protein phosphatase-like N (R-PTP-N) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3) (PTP IA-2) [Cleaved into: ICA512-N-terminal fragment (ICA512-NTF); ICA512-transmembrane fragment (ICA512-TMF); ICA512-cleaved cytosolic fragment (ICA512-CCF)] | Membrane | ||
| Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP) | Cytoplasm | ||
| MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor) | Membrane | ||
| Myelin proteolipid protein (PLP) (Lipophilin) | spastic ataxia X-linked hereditary ataxia | Cell membrane | |
| Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta) | |||
| Ras-related protein Rab-1A (YPT1-related protein) | Golgi apparatus | ||
| Inner nuclear membrane protein Man1 (LEM domain-containing protein 3) | Nucleus inner membrane | ||
| BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1) | |||
| Zinc finger and BTB domain-containing protein 26 (Zinc finger protein 481) (Zinc finger protein Bioref) | Nucleus | ||
| Peptidyl-prolyl cis-trans isomerase FKBP7 (PPIase FKBP7) (EC 5.2.1.8) (23 kDa FK506-binding protein) (23 kDa FKBP) (FKBP-23) (FK506-binding protein 7) (FKBP-7) (Rotamase) | Endoplasmic reticulum lumen | ||
| Neural proliferation differentiation and control protein 1 (NPDC-1) | Membrane | ||
| Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain) | autism spectrum disorder | Cytoplasm | |
| Mucin-16 (MUC-16) (Ovarian cancer-related tumor marker CA125) (CA-125) (Ovarian carcinoma antigen CA125) | |||
| Vitronectin (VN) (S-protein) (Serum-spreading factor) (V75) [Cleaved into: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin-B] | Secreted, extracellular space. | ||
| Myb-related transcription factor, partner of profilin (Myb-related protein p42POP) (Partner of profilin) | Nucleus | ||
| Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (Isocitric dehydrogenase subunit gamma) (NAD(+)-specific ICDH subunit gamma) | Mitochondrion | ||
| Serine-rich coiled-coil domain-containing protein 2 (Coiled-coil serine-rich protein 2) (Protein GCAP14 homolog) | Cytoplasm, cytoskeleton | ||
| Caspase-2 (CASP-2) (EC 3.4.22.55) (Neural precursor cell expressed developmentally down-regulated protein 2) (NEDD-2) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12] | |||
| EKC/KEOPS complex subunit GON7 | Nucleus | ||
| Wnt inhibitory factor 1 (WIF-1) | Secreted. | ||
| UDP-N-acetylglucosamine transporter (Golgi UDP-GlcNAc transporter) (Solute carrier family 35 member A3) | autism spectrum disorder | Golgi apparatus membrane | |
| Syntaxin-19 | Cell membrane | ||
| p53-induced death domain-containing protein 1 (EC 3.4.21.-) (Leucine-rich repeat and death domain-containing protein) [Cleaved into: PIDD-N; PIDD-C; PIDD-CC] | Cytoplasm | ||
| Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (E-NPP 6) (NPP-6) (EC 3.1.4.-) (EC 3.1.4.38) (Choline-specific glycerophosphodiester phosphodiesterase) (Glycerophosphocholine cholinephosphodiesterase) (GPC-Cpde) | Cell membrane | ||
| Leucine-rich repeat and calponin homology domain-containing protein 3 | Secreted | ||
| Placental protein 13-like (Charcot-Leyden crystal protein 2) (CLC2) (Galectin-14) (Gal-14) | Nucleus | ||
| Vacuolar protein-sorting-associated protein 25 (hVps25) (Dermal papilla-derived protein 9) (ELL-associated protein of 20 kDa) (ESCRT-II complex subunit VPS25) | |||
| Cysteine-rich protein 2 (CRP-2) (Protein ESP1) | |||
| 39S ribosomal protein L34, mitochondrial (L34mt) (MRP-L34) (Mitochondrial large ribosomal subunit protein bL34m) | Mitochondrion | ||
| Mediator of RNA polymerase II transcription subunit 14 (Activator-recruited cofactor 150 kDa component) (ARC150) (Cofactor required for Sp1 transcriptional activation subunit 2) (CRSP complex subunit 2) (Mediator complex subunit 14) (RGR1 homolog) (hRGR1) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) | Nucleus | ||
| Protein TSSC4 (Tumor-suppressing STF cDNA 4 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein) | |||
| Pregnancy-specific beta-1-glycoprotein 5 (PS-beta-G-5) (PSBG-5) (Pregnancy-specific glycoprotein 5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3) | Secreted | ||
| Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6) | Nucleus | ||
| Nck-associated protein 1-like (Hematopoietic protein 1) (Membrane-associated protein HEM-1) | Cell membrane | ||
| Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67) | Cell membrane | ||
| Paraplegin (EC 3.4.24.-) (Cell matrix adhesion regulator) (Spastic paraplegia 7 protein) | Mitochondrion inner membrane | ||
| PHD finger-like domain-containing protein 5A (PHD finger-like domain protein 5A) (Splicing factor 3B-associated 14 kDa protein) (SF3b14b) | Nucleus | ||
| Partner of Y14 and mago (PYM homolog 1 exon junction complex-associated factor) (Protein wibg homolog) | Cytoplasm | ||
| Putative uncharacterized protein C9orf106 | |||
| Putative uncharacterized protein MGC163334 | |||
| Pre-mRNA cleavage complex 2 protein Pcf11 (Pre-mRNA cleavage complex II protein Pcf11) | Nucleus. | ||
| Putative uncharacterized protein RUSC1-AS1 (RUSC1 antisense RNA 1) (RUSC1 antisense gene protein 1) | |||
| DNA polymerase beta (EC 2.7.7.7) (EC 4.2.99.-) | |||
| Zinc finger matrin-type protein 3 (Zinc finger protein WIG-1) (p53-activated gene 608 protein) | Nucleus | ||
| SLAIN motif-containing protein 1 | Cytoplasm, cytoskeleton | ||
| Chloride channel protein 2 (ClC-2) | autosomal recessive cerebellar ataxia | Cell membrane | |
| SprT-like domain-containing protein Spartan (DNA damage protein targeting VCP) (DVC1) (Protein with SprT-like domain at the N terminus) (Spartan) | |||
| Checkpoint protein HUS1B (hHUS1B) | |||
| DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3) | Isoform 1: Mitochondrion | ||
| Zinc finger protein Aiolos (Ikaros family zinc finger protein 3) | Nucleus | ||
| Ribosomal RNA small subunit methyltransferase NEP1 (EC 2.1.1.-) (18S rRNA (pseudouridine(1248)-N1)-methyltransferase) (18S rRNA Psi1248 methyltransferase) (Nucleolar protein EMG1 homolog) (Protein C2f) (Ribosome biogenesis protein NEP1) | Nucleus, nucleolus | ||
| RNA-binding protein 5 (Protein G15) (Putative tumor suppressor LUCA15) (RNA-binding motif protein 5) (Renal carcinoma antigen NY-REN-9) | Nucleus | ||
| Valacyclovir hydrolase (VACVase) (Valacyclovirase) (EC 3.1.-.-) (Biphenyl hydrolase-like protein) (Biphenyl hydrolase-related protein) (Bph-rp) (Breast epithelial mucin-associated antigen) (MCNAA) | |||
| Splicing factor 3A subunit 3 (SF3a60) (Spliceosome-associated protein 61) (SAP 61) | Nucleus speckle. | ||
| Derlin-2 (Degradation in endoplasmic reticulum protein 2) (DERtrin-2) (Der1-like protein 2) (F-LAN-1) (F-LANa) | Endoplasmic reticulum membrane | ||
| DNA repair protein complementing XP-C cells (Xeroderma pigmentosum group C-complementing protein) (p125) | |||
| POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (BOB-1) (OCA-B) (OCT-binding factor 1) | Nucleus. | ||
| Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3) (Proliferation-related kinase) | |||
| Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII) (TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b) (Etanercept) [Cleaved into: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBP-2) (TBPII)] | Isoform 1: Cell membrane | ||
| Cytokine receptor common subunit beta (CDw131) (GM-CSF/IL-3/IL-5 receptor common beta subunit) (CD antigen CD131) | Membrane | ||
| Protein phosphatase 1 regulatory subunit 1A (Protein phosphatase inhibitor 1) (I-1) (IPP-1) | |||
| Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) | Cytoplasm. | ||
| Transcription initiation factor TFIID subunit 1-like (TAF(II)210) (TBP-associated factor 1-like) (TBP-associated factor 210 kDa) (Transcription initiation factor TFIID 210 kDa subunit) | Nucleus | ||
| Neuroendocrine protein 7B2 (Pituitary polypeptide) (Secretogranin V) (Secretogranin-5) (Secretory granule endocrine protein I) [Cleaved into: N-terminal peptide; C-terminal peptide] | |||
| LYR motif-containing protein 1 | Nucleus | ||
| Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1) | Cytoplasm | ||
| E3 ubiquitin-protein ligase TRIM22 (EC 2.3.2.27) (50 kDa-stimulated trans-acting factor) (RING finger protein 94) (RING-type E3 ubiquitin transferase TRIM22) (Staf-50) (Tripartite motif-containing protein 22) | Cytoplasm | ||
| Septin-5 (Cell division control-related protein 1) (CDCrel-1) (Peanut-like protein 1) | Cytoplasm | ||
| Calcium-binding mitochondrial carrier protein SCaMC-1 (Mitochondrial ATP-Mg/Pi carrier protein 1) (Mitochondrial Ca(2+)-dependent solute carrier protein 1) (Small calcium-binding mitochondrial carrier protein 1) (Solute carrier family 25 member 24) | Mitochondrion inner membrane | ||
| Mitochondrial import receptor subunit TOM70 (Mitochondrial precursor proteins import receptor) (Translocase of outer membrane 70 kDa subunit) (Translocase of outer mitochondrial membrane protein 70) | Mitochondrion outer membrane | ||
| Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1) | Cytoplasm | ||
| Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Acyl-CoA synthetase 1) (ACS1) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Long-chain acyl-CoA synthetase 2) (LACS 2) (Long-chain fatty acid-CoA ligase 2) (Palmitoyl-CoA ligase 1) (Palmitoyl-CoA ligase 2) | Mitochondrion outer membrane | ||
| NADH-cytochrome b5 reductase 1 (b5R.1) (EC 1.6.2.2) (Humb5R2) (NAD(P)H:quinone oxidoreductase type 3 polypeptide A2) | Membrane | ||
| SH2 domain-containing protein 4A (Protein SH(2)A) (Protein phosphatase 1 regulatory subunit 38) | Cytoplasm | ||
| Mitofusin-2 (EC 3.6.5.-) (Transmembrane GTPase MFN2) | Mitochondrion outer membrane | ||
| Ubiquitin-conjugating enzyme E2 J2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J2) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE-2) | Endoplasmic reticulum membrane | ||
| Mitochondrial amidoxime-reducing component 1 (mARC1) (EC 1.-.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 1) (MOSC domain-containing protein 1) (Moco sulfurase C-terminal domain-containing protein 1) | Mitochondrion outer membrane | ||
| UPF0183 protein C16orf70 | |||
| F-BAR and double SH3 domains protein 2 (Carom) (SH3 multiple domains protein 3) | |||
| Melanoregulin (Dilute suppressor protein homolog) | Apical cell membrane | ||
| Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110) | Cytoplasm | ||
| Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1) | Cytoplasm, cytoskeleton | ||
| Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2 homolog) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase) | Membrane | ||
| Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8) | Cytoplasm. | ||
| Rho guanine nucleotide exchange factor 26 (SH3 domain-containing guanine exchange factor) | Cell projection, ruffle | ||
| McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (Bardet-Biedl syndrome 6 protein) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Photoreceptor ankyrin repeat protein (Ankyrin repeat domain-containing protein 33) | Cytoplasm, cytosol | ||
| Dystroglycan (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)] | Alpha-dystroglycan: Secreted, extracellular space. | ||
| Sialic acid-binding Ig-like lectin 10 (Siglec-10) (Siglec-like protein 2) | Isoform 1: Cell membrane | ||
| Protein tyrosine phosphatase receptor type C-associated protein (PTPRC-associated protein) (CD45-associated protein) (CD45-AP) (Lymphocyte phosphatase-associated phosphoprotein) | Membrane | ||
| Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5) | Cytoplasm | ||
| Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase) | Cytoplasm | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 (B17.2-like) (B17.2L) (Mimitin) (Myc-induced mitochondrial protein) (MMTN) (NDUFA12-like protein) | Parkinson disease | Mitochondrion | |
| E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL) | Cytoplasm | ||
| Zymogen granule membrane protein 16 (Zymogen granule protein 16) (hZG16) (Secretory lectin ZG16) | Secreted, extracellular space, extracellular matrix | ||
| Peroxiredoxin-like 2A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM) (Redox-regulatory protein FAM213A) | Cytoplasm | ||
| Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane adapter protein PAG) (Transmembrane phosphoprotein Cbp) | Cell membrane | ||
| Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3) | Isoform 1: Cell membrane | ||
| U6 snRNA-associated Sm-like protein LSm6 | Cytoplasm | ||
| Acyl-CoA-binding domain-containing protein 5 | Peroxisome membrane | ||
| Transforming growth factor beta-1-induced transcript 1 protein (Androgen receptor coactivator 55 kDa protein) (Androgen receptor-associated protein of 55 kDa) (Hydrogen peroxide-inducible clone 5 protein) (Hic-5) | |||
| T-cell surface glycoprotein CD3 zeta chain (T-cell receptor T3 zeta chain) (CD antigen CD247) | Membrane | ||
| Sestrin-1 (EC 1.11.1.15) (p53-regulated protein PA26) | Nucleus | ||
| Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45) | multiple sclerosis | Cell membrane | |
| Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta] | Cell membrane | ||
| UPF0449 protein C19orf25 | |||
| Sestrin-2 (EC 1.11.1.15) (Hypoxia-induced gene) | Cytoplasm | ||
| Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53) | |||
| Centromere/kinetochore protein zw10 homolog | Cytoplasm | ||
| P2Y purinoceptor 8 (P2Y8) | Cell membrane | ||
| Vesicle transport protein USE1 (Putative MAPK-activating protein PM26) (USE1-like protein) (p31) | Endoplasmic reticulum membrane | ||
| Protein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiated inhibitory protein of PP1) (Protein kinase C-potentiated inhibitor protein of 17 kDa) (CPI-17) | Cytoplasm | ||
| Fibroblast growth factor 13 (FGF-13) (Fibroblast growth factor homologous factor 2) (FHF-2) | Cell projection, filopodium | ||
| High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) | Cell membrane | ||
| Acetyl-coenzyme A transporter 1 (AT-1) (Acetyl-CoA transporter 1) (Solute carrier family 33 member 1) | Endoplasmic reticulum membrane | ||
| UBX domain-containing protein 8 (Reproduction 8 protein) (Rep-8 protein) (UBX domain-containing protein 6) | Endoplasmic reticulum membrane | ||
| Cation channel sperm-associated protein 2 (CatSper2) | Cell projection, cilium, flagellum membrane | ||
| Thymic stromal lymphopoietin | Secreted | ||
| Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (TRAF6-regulated IKK activator 1 beta Uev1A) | Nucleus | ||
| E3 ubiquitin-protein ligase SMURF2 (hSMURF2) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase SMURF2) (SMAD ubiquitination regulatory factor 2) (SMAD-specific E3 ubiquitin-protein ligase 2) | Nucleus | ||
| Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) | |||
| Zinc finger protein 114 | Nucleus | ||
| Pre-mRNA-splicing factor 18 (PRP18 homolog) (hPRP18) | Nucleus speckle | ||
| Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT) | Membrane | ||
| Forkhead box protein O3 (AF6q21 protein) (Forkhead in rhabdomyosarcoma-like 1) | Cytoplasm, cytosol | ||
| 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH) (EC 1.2.1.47) (Aldehyde dehydrogenase E3 isozyme) (Aldehyde dehydrogenase family 9 member A1) (EC 1.2.1.3) (Gamma-aminobutyraldehyde dehydrogenase) (EC 1.2.1.19) (R-aminobutyraldehyde dehydrogenase) [Cleaved into: 4-trimethylaminobutyraldehyde dehydrogenase, N-terminally processed] | Cytoplasm | ||
| Transmembrane protein 43 (Protein LUMA) | Endoplasmic reticulum | ||
| Signal recognition particle 19 kDa protein (SRP19) | Cytoplasm. | ||
| Histone deacetylase complex subunit SAP30 (30 kDa Sin3-associated polypeptide) (Sin3 corepressor complex subunit SAP30) (Sin3-associated polypeptide p30) | Nucleus. | ||
| Collagen alpha-1(IV) chain [Cleaved into: Arresten] | Secreted, extracellular space, extracellular matrix, basement membrane | ||
| Sperm-associated antigen 11B (Human epididymis-specific protein 2) (He2) (Protein EP2) (Sperm antigen HE2) | Secreted. | ||
| Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3) | Nucleus. | ||
| Neuronal vesicle trafficking-associated protein 1 (Neuron-enriched endosomal protein of 21 kDa) (Neuron-specific protein family member 1) | Membrane | ||
| Small EDRK-rich factor 1 (Protein 4F5) (h4F5) (SMA modifier 1) | spinal muscular atrophy | ||
| Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3) | Nucleus | ||
| Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TAK1) (Orphan nuclear receptor TR4) (Testicular receptor 4) | Nucleus | ||
| Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone) | Cytoplasm | ||
| UPF0545 protein C22orf39 | |||
| Protein BANP (BEN domain-containing protein 1) (Btg3-associated nuclear protein) (Scaffold/matrix-associated region-1-binding protein) | Nucleus | ||
| Major prion protein (PrP) (ASCR) (PrP27-30) (PrP33-35C) (CD antigen CD230) | Huntington disease | Cell membrane | |
| Tumor necrosis factor receptor superfamily member 25 (Apo-3) (Apoptosis-inducing receptor AIR) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death receptor 3) (Lymphocyte-associated receptor of death) (LARD) (Protein WSL) (Protein WSL-1) | Isoform 1: Cell membrane | ||
| Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor) | Cell membrane | ||
| Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)] | Cytoplasm | ||
| Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (Testis development protein NYD-SP19) | Isoform 1: Nucleus. | ||
| Protein mago nashi homolog | Nucleus | ||
| Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog) (fSAPb) | Nucleus | ||
| Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 2) (NLI-interacting factor 2) (Protein OS-4) (Small C-terminal domain phosphatase 2) (Small CTD phosphatase 2) (SCP2) | Nucleus | ||
| DENN domain-containing protein 2D | Cytoplasm | ||
| UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT) | Golgi apparatus membrane | ||
| Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor) | Cell membrane | ||
| Solute carrier family 25 member 48 | Mitochondrion inner membrane | ||
| Docking protein 4 (Downstream of tyrosine kinase 4) (Insulin receptor substrate 5) (IRS-5) (IRS5) | |||
| Growth/differentiation factor 15 (GDF-15) (Macrophage inhibitory cytokine 1) (MIC-1) (NSAID-activated gene 1 protein) (NAG-1) (NSAID-regulated gene 1 protein) (NRG-1) (Placental TGF-beta) (Placental bone morphogenetic protein) (Prostate differentiation factor) | Secreted | ||
| Serum amyloid A-2 protein (SAA2) | Secreted. | ||
| Protein FRG1 (FSHD region gene 1 protein) | progressive muscular atrophy | Nucleus, Cajal body | |
| Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Sodium-coupled branched-chain amino-acid transporter 1) (Solute carrier family 6 member 15) (Transporter v7-3) | Membrane | ||
| Spliceosome-associated protein CWC27 homolog (Antigen NY-CO-10) (Probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog) (PPIase CWC27) (Serologically defined colon cancer antigen 10) | Nucleus | ||
| Calcium-binding mitochondrial carrier protein SCaMC-2 (Mitochondrial ATP-Mg/Pi carrier protein 3) (Mitochondrial Ca(2+)-dependent solute carrier protein 3) (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25) | Mitochondrion inner membrane | ||
| Charged multivesicular body protein 3 (Chromatin-modifying protein 3) (Neuroendocrine differentiation factor) (Vacuolar protein sorting-associated protein 24) (hVps24) | Cytoplasm, cytosol | ||
| Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1) | Cytoplasm | ||
| Septin-1 (LARP) (Peanut-like protein 3) (Serologically defined breast cancer antigen NY-BR-24) | Cytoplasm | ||
| Retrotransposon Gag-like protein 8A (Mammalian retrotransposon derived protein 8A) | |||
| Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Cardiac voltage-gated potassium channel modulatory subunit) (Potassium channel-interacting protein 2) | Isoform 1: Cell membrane | ||
| C-X-C motif chemokine 16 (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein) (SR-PSOX) (Small-inducible cytokine B16) (Transmembrane chemokine CXCL16) | Cell membrane | ||
| Transmembrane protein 239 | Membrane | ||
| Zinc transporter ZIP2 (6A1) (Eti-1) (Solute carrier family 39 member 2) (Zrt- and Irt-like protein 2) (ZIP-2) (hZIP2) | Cell membrane | ||
| Cytochrome b-c1 complex subunit 9 (Complex III subunit 9) (Complex III subunit X) (Cytochrome c1 non-heme 7 kDa protein) (Ubiquinol-cytochrome c reductase complex 7.2 kDa protein) | Mitochondrion inner membrane | ||
| Cytochrome c-type heme lyase (CCHL) (EC 4.4.1.17) (Holocytochrome c-type synthase) | Mitochondrion inner membrane | ||
| Phospholipase B1, membrane-associated (Phospholipase B) (hPLB) (Phospholipase B/lipase) (PLB/LIP) [Includes: Phospholipase A2 (EC 3.1.1.4); Lysophospholipase (EC 3.1.1.5)] | Apical cell membrane | ||
| C-C motif chemokine 3 (G0/G1 switch regulatory protein 19-1) (Macrophage inflammatory protein 1-alpha) (MIP-1-alpha) (PAT 464.1) (SIS-beta) (Small-inducible cytokine A3) (Tonsillar lymphocyte LD78 alpha protein) [Cleaved into: MIP-1-alpha(4-69) (LD78-alpha(4-69))] | Secreted. | ||
| Insulin-degrading enzyme (EC 3.4.24.56) (Abeta-degrading protease) (Insulin protease) (Insulinase) (Insulysin) | Cytoplasm | ||
| Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64) | Cytoplasm | ||
| SAC3 domain-containing protein 1 (SAC3 homology domain-containing protein 1) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Signal transducing adapter molecule 1 (STAM-1) | Cytoplasm | ||
| Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk) | Cell membrane | ||
| Sodium channel protein type 2 subunit alpha (HBSC II) (Sodium channel protein brain II subunit alpha) (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) | autism spectrum disorder | Cell membrane | |
| Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP) | Cytoplasm | ||
| Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase (EC 2.4.99.8) (Alpha-2,8-sialyltransferase 8A) (Ganglioside GD3 synthase) (Ganglioside GT3 synthase) (Sialyltransferase 8A) (SIAT8-A) (Sialyltransferase St8Sia I) (ST8SiaI) | Golgi apparatus membrane | ||
| Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta) | Cytoplasm | ||
| Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)] | lateral sclerosis amyotrophic lateral sclerosis | Cell membrane | |
| Moesin (Membrane-organizing extension spike protein) | Cell membrane | ||
| Neural Wiskott-Aldrich syndrome protein (N-WASP) | Cytoplasm, cytoskeleton | ||
| Actin-related protein 3 (Actin-like protein 3) | Cytoplasm, cytoskeleton | ||
| Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met) | autism spectrum disorder | Membrane | |
| Guanine nucleotide exchange factor VAV2 (VAV-2) | |||
| Proheparin-binding EGF-like growth factor [Cleaved into: Heparin-binding EGF-like growth factor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R)] | |||
| Hepatocyte growth factor (Hepatopoietin-A) (Scatter factor) (SF) [Cleaved into: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain] | |||
| RWD domain-containing protein 3 (RWD domain-containing sumoylation enhancer) (RSUME) | Nucleus | ||
| Heat shock factor 2-binding protein | Cytoplasm | ||
| DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA) | Nucleus | ||
| AP-4 complex subunit sigma-1 (AP-4 adaptor complex subunit sigma-1) (Adaptor-related protein complex 4 subunit sigma-1) (Sigma-1 subunit of AP-4) (Sigma-4-adaptin) (Sigma4-adaptin) | Golgi apparatus, trans-Golgi network membrane | ||
| Fibronectin type III and SPRY domain-containing protein 2 (SPRY domain-containing protein 1) | Nucleus | ||
| ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP) | Peroxisome membrane | ||
| Erythroid transcription factor (Eryf1) (GATA-binding factor 1) (GATA-1) (GF-1) (NF-E1 DNA-binding protein) | Nucleus. | ||
| Suppressor of tumorigenicity 20 protein (Human cervical cancer suppressor gene 1 protein) (HCCS-1) | |||
| E3 ubiquitin-protein ligase BRE1A (BRE1-A) (hBRE1) (EC 2.3.2.27) (RING finger protein 20) (RING-type E3 ubiquitin transferase BRE1A) | Nucleus | ||
| RNA polymerase-associated protein RTF1 homolog | Nucleus, nucleoplasm | ||
| Testis-specific gene 10 protein (Testis development protein NYD-SP7) | Cytoplasm | ||
| Secretory carrier-associated membrane protein 3 (Secretory carrier membrane protein 3) | Membrane | ||
| 39S ribosomal protein L52, mitochondrial (L52mt) (MRP-L52) (Mitochondrial large ribosomal subunit protein mL52) | Mitochondrion | ||
| Mitochondrial import receptor subunit TOM20 homolog (Mitochondrial 20 kDa outer membrane protein) (Outer mitochondrial membrane receptor Tom20) | Mitochondrion outer membrane | ||
| 5-aminolevulinate synthase, nonspecific, mitochondrial (ALAS-H) (EC 2.3.1.37) (5-aminolevulinic acid synthase 1) (Delta-ALA synthase 1) (Delta-aminolevulinate synthase 1) | Mitochondrion matrix. | ||
| Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (hHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A) | |||
| N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 (DDAH-2) (Dimethylarginine dimethylaminohydrolase 2) (EC 3.5.3.18) (DDAHII) (Dimethylargininase-2) (Protein G6a) (S-phase protein) | Cytoplasm | ||
| Cytochrome b-c1 complex subunit 8 (Complex III subunit 8) (Complex III subunit VIII) (Ubiquinol-cytochrome c reductase complex 9.5 kDa protein) (Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C) | Mitochondrion inner membrane. | ||
| Ubiquitin-conjugating enzyme E2 B (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme B) (RAD6 homolog B) (HR6B) (hHR6B) (Ubiquitin carrier protein B) (Ubiquitin-conjugating enzyme E2-17 kDa) (Ubiquitin-protein ligase B) | Cell membrane | ||
| Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o) | Nucleus. | ||
| RNA polymerase-associated protein LEO1 (Replicative senescence down-regulated leo1-like protein) | Nucleus | ||
| Cerebellar degeneration-related protein 2-like (Paraneoplastic 62 kDa antigen) | |||
| Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B) (EC 5.2.1.8) (12.6 kDa FK506-binding protein) (12.6 kDa FKBP) (FKBP-12.6) (FK506-binding protein 1B) (FKBP-1B) (Immunophilin FKBP12.6) (Rotamase) (h-FKBP-12) | Cytoplasm | ||
| Zinc finger protein 587 | Nucleus | ||
| Putative sodium-coupled neutral amino acid transporter 7 (Solute carrier family 38 member 7) | Membrane | ||
| Testis-specific protein 10-interacting protein (Tsga10-interacting protein) | |||
| DAZ-associated protein 2 (Deleted in azoospermia-associated protein 2) | |||
| Probable UDP-sugar transporter protein SLC35A4 (Solute carrier family 35 member A4) | Golgi apparatus membrane | ||
| Coilin (p80-coilin) | Nucleus | ||
| Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140) | Nucleus | ||
| Zinc finger protein 417 | Nucleus | ||
| General transcription and DNA repair factor IIH helicase subunit XPB (TFIIH subunit XPB) (EC 3.6.4.12) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein) | Nucleus. | ||
| Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin homolog 1) (Latrophilin-2) (Lectomedin-1) | Membrane | ||
| U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO-16) (Serologically defined colon cancer antigen 16) | Nucleus, nucleolus | ||
| Ephrin-A2 (EPH-related receptor tyrosine kinase ligand 6) (LERK-6) (HEK7 ligand) (HEK7-L) | Cell membrane | ||
| Methyltransferase-like protein 17, mitochondrial (EC 2.1.1.-) (False p73 target gene protein) (Methyltransferase 11 domain-containing protein 1) (Protein RSM22 homolog, mitochondrial) | Mitochondrion | ||
| Protein FAM118B | Nucleus, Cajal body | ||
| Zinc transporter ZIP9 (Solute carrier family 39 member 9) (Zrt- and Irt-like protein 9) (ZIP-9) | Membrane | ||
| Serum amyloid A-1 protein (SAA) [Cleaved into: Amyloid protein A (Amyloid fibril protein AA); Serum amyloid protein A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(2-103); Serum amyloid protein A(2-102); Serum amyloid protein A(4-101)] | Secreted | ||
| Leukocyte receptor cluster member 1 | |||
| Protein PIMREG (CALM-interactor expressed in thymus and spleen) (PICALM-interacting mitotic regulator) (Regulator of chromosome segregation protein 1) | Nucleus | ||
| Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2) | Cytoplasmic vesicle membrane | ||
| Pre-mRNA-splicing factor SLU7 (hSlu7) | |||
| Zinc finger and SCAN domain-containing protein 12 (Zinc finger protein 305) (Zinc finger protein 96) | Nucleus | ||
| Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) | Cytoplasm | ||
| Sulfiredoxin-1 (EC 1.8.98.2) | Cytoplasm | ||
| Schlafen family member 5 | |||
| Serpin H1 (47 kDa heat shock protein) (Arsenic-transactivated protein 3) (AsTP3) (Cell proliferation-inducing gene 14 protein) (Collagen-binding protein) (Colligin) (Rheumatoid arthritis-related antigen RA-A47) | Endoplasmic reticulum lumen. | ||
| Transcription initiation factor TFIID subunit 7-like (Cancer/testis antigen 40) (CT40) (RNA polymerase II TBP-associated factor subunit Q) (TATA box-binding protein-associated factor 50 kDa) (Transcription initiation factor TFIID 50 kDa subunit) | Nucleus | ||
| Leukocyte receptor cluster member 8 | |||
| SET domain-containing protein 5 | autism spectrum disorder | Nucleus | |
| Zinc finger protein 410 (Another partner for ARF 1) (Zinc finger protein APA-1) | Nucleus | ||
| Zinc finger CCHC domain-containing protein 10 | |||
| Glutathione peroxidase 7 (GPx-7) (GSHPx-7) (EC 1.11.1.9) (CL683) | Secreted | ||
| Histone acetyltransferase KAT7 (EC 2.3.1.48) (Histone acetyltransferase binding to ORC1) (Lysine acetyltransferase 7) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (MYST-2) | Nucleus, nucleoplasm | ||
| Serglycin (Hematopoietic proteoglycan core protein) (Platelet proteoglycan core protein) (P.PG) (Secretory granule proteoglycan core protein) | Cytoplasmic granule | ||
| Transcription elongation factor A N-terminal and central domain-containing protein 2 | Nucleus | ||
| Protein lin-37 homolog (Antolefinin) | |||
| Sphingomyelin phosphodiesterase 2 (EC 3.1.4.12) (Lyso-platelet-activating factor-phospholipase C) (Lyso-PAF-PLC) (Neutral sphingomyelinase) (N-SMase) (nSMase) | Membrane | ||
| Microfibrillar-associated protein 1 (Spliceosome B complex protein MFAP1) | Nucleus | ||
| Protein FAM161A | Cytoplasm, cytoskeleton, cilium basal body | ||
| ALX homeobox protein 1 (Cartilage homeoprotein 1) (CART-1) | Nucleus | ||
| Mitochondrial import inner membrane translocase subunit TIM16 (Mitochondria-associated granulocyte macrophage CSF-signaling molecule) (Presequence translocated-associated motor subunit PAM16) | Mitochondrion inner membrane | ||
| Actin-binding LIM protein 2 (abLIM-2) (Actin-binding LIM protein family member 2) | |||
| Probable E3 ubiquitin-protein ligase DTX3 (EC 2.3.2.27) (Protein deltex-3) (Deltex3) (RING finger protein 154) (RING-type E3 ubiquitin transferase DTX3) | Cytoplasm | ||
| Growth factor receptor-bound protein 14 (GRB14 adapter protein) | lateral sclerosis | Cytoplasm | |
| Solute carrier family 22 member 11 (Organic anion transporter 4) | Cell membrane | ||
| E3 ubiquitin-protein ligase ZNRF1 (EC 2.3.2.27) (Nerve injury-induced gene 283 protein) (RING-type E3 ubiquitin transferase ZNRF1) (Zinc/RING finger protein 1) | Endosome | ||
| Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit) | Isoform 1: Cytoplasm | ||
| Trimethyllysine dioxygenase, mitochondrial (EC 1.14.11.8) (Epsilon-trimethyllysine 2-oxoglutarate dioxygenase) (Epsilon-trimethyllysine hydroxylase) (TML hydroxylase) (TML-alpha-ketoglutarate dioxygenase) (TML dioxygenase) (TMLD) | autism spectrum disorder | Mitochondrion matrix | |
| E3 ubiquitin-protein ligase TRIM50 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM50) (Tripartite motif-containing protein 50) | Cytoplasm | ||
| Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 (28S ribosomal protein S37, mitochondrial) (MRP-S37) (Mitochondrial small ribosomal subunit protein mS37) (Nuclear protein C2360) | Mitochondrion | ||
| Ribosome-releasing factor 2, mitochondrial (RRF2mt) (Elongation factor G 2, mitochondrial) (EF-G2mt) (mEF-G 2) (Elongation factor G2) (hEFG2) | Mitochondrion | ||
| Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (PP2C domain-containing protein phosphatase 1K) (PP2C-like mitochondrial protein) (PP2C-type mitochondrial phosphoprotein phosphatase) (PTMP) (Protein phosphatase 2C isoform kappa) (PP2C-kappa) | Mitochondrion matrix | ||
| Nardilysin (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C) (Nardilysin convertase) | |||
| Kunitz-type protease inhibitor 1 (Hepatocyte growth factor activator inhibitor type 1) (HAI-1) | Secreted. | ||
| Mitochondrial-processing peptidase subunit alpha (Alpha-MPP) (P-55) | autosomal recessive cerebellar ataxia | Mitochondrion matrix | |
| AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein) | autosomal dominant cerebellar ataxia autosomal recessive cerebellar ataxia spastic ataxia | Mitochondrion | |
| Hepatocyte growth factor activator (HGF activator) (HGFA) (EC 3.4.21.-) [Cleaved into: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain] | |||
| Probable asparagine--tRNA ligase, mitochondrial (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS) | Mitochondrion matrix | ||
| Low-density lipoprotein receptor-related protein 10 (LRP-10) | Membrane | ||
| AFG1-like ATPase (Lactation elevated protein 1) (EC 3.6.-.-) (Protein AFG1 homolog) | Mitochondrion membrane | ||
| Protein FAM136A | |||
| Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (NADPH-dependent retinol dehydrogenase/reductase) (NRDR) (humNRDR) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD) (SCAD-SRL) (Short chain dehydrogenase/reductase family 25C member 2) (Short-chain dehydrogenase/reductase family member 4) | Peroxisome | ||
| Ubiquinol-cytochrome-c reductase complex assembly factor 2 (Breast cancer-associated protein SGA-81M) (Mitochondrial nucleoid factor 1) (Mitochondrial protein M19) | Mitochondrion matrix, mitochondrion nucleoid | ||
| Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase 4) (Coenzyme Q protein 8B) | Mitochondrion membrane | ||
| Peptidyl-tRNA hydrolase 2, mitochondrial (PTH 2) (EC 3.1.1.29) (Bcl-2 inhibitor of transcription 1) | Mitochondrion. | ||
| Endoribonuclease YbeY (EC 3.1.-.-) | Nucleus | ||
| tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase) | |||
| Peptidyl-prolyl cis-trans isomerase FKBP10 (PPIase FKBP10) (EC 5.2.1.8) (65 kDa FK506-binding protein) (65 kDa FKBP) (FKBP-65) (FK506-binding protein 10) (FKBP-10) (Immunophilin FKBP65) (Rotamase) | Endoplasmic reticulum lumen | ||
| Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-) | Membrane | ||
| Uncharacterized aarF domain-containing protein kinase 1 (EC 2.7.11.-) | Secreted | ||
| Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (Interphase cytoplasmic foci protein 45) (tRNA-histidine guanylyltransferase) | Cytoplasm | ||
| R-spondin-2 (Roof plate-specific spondin-2) (hRspo2) | Secreted | ||
| Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial (Coenzyme Q biosynthesis protein 4 homolog) | Isoform 1: Mitochondrion inner membrane | ||
| SPRY domain-containing protein 4 | |||
| Ubiquinone biosynthesis O-methyltransferase, mitochondrial (3-demethylubiquinol 3-O-methyltransferase) (EC 2.1.1.64) (Polyprenyldihydroxybenzoate methyltransferase) (EC 2.1.1.114) | Mitochondrion inner membrane | ||
| LIM/homeobox protein Lhx4 (LIM homeobox protein 4) | Nucleus | ||
| Polymeric immunoglobulin receptor (PIgR) (Poly-Ig receptor) (Hepatocellular carcinoma-associated protein TB6) [Cleaved into: Secretory component] | Cell membrane | ||
| m-AAA protease-interacting protein 1, mitochondrial (Matrix AAA peptidase-interacting protein 1) | Mitochondrion matrix | ||
| Transmembrane protein 126A | Mitochondrion inner membrane | ||
| DNA-directed RNA polymerase III subunit RPC9 (RNA polymerase III subunit C9) (Calcitonin gene-related peptide-receptor component protein) (CGRP-RCP) (CGRP-receptor component protein) (CGRPRCP) (HsC17) | Nucleus | ||
| Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3) | |||
| Dynamin-1-like protein (EC 3.6.5.5) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-like protein) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV) (Dynamin-related protein 1) | Alzheimer disease | Cytoplasm, cytosol | |
| Mitochondrial dynamics protein MID51 (Mitochondrial dynamics protein of 51 kDa) (Mitochondrial elongation factor 1) (Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like) (SMCR7-like protein) | Mitochondrion outer membrane | ||
| Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1) | Nucleus | ||
| Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1) | Parkinson disease | Mitochondrion outer membrane | |
| Mitochondrial ubiquitin ligase activator of NFKB 1 (EC 2.3.2.27) (E3 SUMO-protein ligase MUL1) (E3 ubiquitin-protein ligase MUL1) (Growth inhibition and death E3 ligase) (Mitochondrial-anchored protein ligase) (MAPL) (Putative NF-kappa-B-activating protein 266) (RING finger protein 218) (RING-type E3 ubiquitin transferase NFKB 1) | |||
| Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H) | |||
| Mitochondrial dynamics protein MID49 (Mitochondrial dynamics protein of 49 kDa) (Mitochondrial elongation factor 2) (Smith-Magenis syndrome chromosomal region candidate gene 7 protein) | Mitochondrion outer membrane | ||
| Secretogranin-3 (Secretogranin III) (SgIII) | Cytoplasmic vesicle, secretory vesicle lumen | ||
| Gamma-aminobutyric acid receptor subunit rho-1 (GABA(A) receptor subunit rho-1) (GABA(C) receptor) | Cell junction, synapse, postsynaptic cell membrane | ||
| Mitochondrial fission 1 protein (FIS1 homolog) (hFis1) (Tetratricopeptide repeat protein 11) (TPR repeat protein 11) | Mitochondrion outer membrane | ||
| Protein kintoun (Dynein assembly factor 2, axonemal) | Cytoplasm | ||
| Deoxyguanosine kinase, mitochondrial (dGK) (EC 2.7.1.113) | Mitochondrion. | ||
| Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1) | Cytoplasm | ||
| Mitochondrial fission factor | Mitochondrion outer membrane | ||
| Protein sprouty homolog 3 (Spry-3) | |||
| Teneurin-1 (Ten-1) (Protein Odd Oz/ten-m homolog 1) (Tenascin-M1) (Ten-m1) (Teneurin transmembrane protein 1) [Cleaved into: Ten-1 intracellular domain (IDten-1) (Ten-1 ICD); Teneurin C-terminal-associated peptide (TCPA-1) (Ten-1 extracellular domain) (Ten-1 ECD)] | autism spectrum disorder | Cell membrane | |
| Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein | lateral sclerosis | Cytoplasm | |
| E3 SUMO-protein ligase PIAS2 (EC 2.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (E3 SUMO-protein transferase PIAS2) (Msx-interacting zinc finger protein) (Miz1) (PIAS-NY protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2) | Nucleus speckle | ||
| Toll-like receptor 3 (CD antigen CD283) | Endoplasmic reticulum membrane | ||
| Prostaglandin E2 receptor EP4 subtype (PGE receptor EP4 subtype) (PGE2 receptor EP4 subtype) (Prostanoid EP4 receptor) | Cell membrane | ||
| E3 SUMO-protein ligase PIAS1 (EC 2.3.2.-) (DEAD/H box-binding protein 1) (E3 SUMO-protein transferase PIAS1) (Gu-binding protein) (GBP) (Protein inhibitor of activated STAT protein 1) (RNA helicase II-binding protein) | Nucleus speckle | ||
| Interleukin-17A (IL-17) (IL-17A) (Cytotoxic T-lymphocyte-associated antigen 8) (CTLA-8) | Secreted. | ||
| NADH-ubiquinone oxidoreductase chain 2 (EC 7.1.1.2) (NADH dehydrogenase subunit 2) | Alzheimer disease | Mitochondrion inner membrane | |
| T-cell leukemia/lymphoma protein 1A (Oncogene TCL-1) (Oncogene TCL1) (Protein p14 TCL1) | Cytoplasm | ||
| Receptor expression-enhancing protein 3 | autism spectrum disorder | Endoplasmic reticulum membrane | |
| Calcium-responsive transcription factor (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) (Calcium-response factor) (CaRF) (Testis development protein NYD-SP24) | lateral sclerosis | Nucleus | |
| Rho GTPase-activating protein 23 (Rho-type GTPase-activating protein 23) | |||
| FERM domain-containing protein 4A | autosomal recessive cerebellar ataxia | Cytoplasm, cytoskeleton | |
| Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase) | |||
| Bromodomain adjacent to zinc finger domain protein 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3) | Nucleus, nucleolus | ||
| GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD) | |||
| Protein fosB (G0/G1 switch regulatory protein 3) | Nucleus. | ||
| Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1) | Nucleus | ||
| Reactive oxygen species modulator 1 (ROS modulator 1) (Epididymis tissue protein Li 175) (Glyrichin) (Mitochondrial targeting GxxxG motif protein) (MTGM) (Protein MGR2 homolog) | Mitochondrion inner membrane | ||
| Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2) | autism spectrum disorder | Nucleus | |
| Transmembrane 9 superfamily member 1 (MP70 protein family member) (hMP70) | Lysosome membrane | ||
| General transcription factor IIH subunit 2 (Basic transcription factor 2 44 kDa subunit) (BTF2 p44) (General transcription factor IIH polypeptide 2) (TFIIH basal transcription factor complex p44 subunit) | spinal muscular atrophy | Nucleus | |
| Cyclic AMP-dependent transcription factor ATF-4 (cAMP-dependent transcription factor ATF-4) (Activating transcription factor 4) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (DNA-binding protein TAXREB67) (Tax-responsive enhancer element-binding protein 67) (TaxREB67) | Cytoplasm | ||
| Glucocorticoid modulatory element-binding protein 1 (GMEB-1) (DNA-binding protein p96PIF) (Parvovirus initiation factor p96) (PIF p96) | |||
| Uncharacterized aarF domain-containing protein kinase 2 (EC 2.7.11.-) | Membrane | ||
| Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) (hTll) | Nucleus | ||
| E3 ubiquitin-protein ligase RNF216 (EC 2.3.2.27) (RING finger protein 216) (RING-type E3 ubiquitin transferase RNF216) (Triad domain-containing protein 3) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) | Cytoplasm. | ||
| Fos-related antigen 1 (FRA-1) | Nucleus. | ||
| Transcription factor jun-B | Nucleus. | ||
| Bile salt sulfotransferase (EC 2.8.2.14) (Dehydroepiandrosterone sulfotransferase) (DHEA-ST) (Hydroxysteroid Sulfotransferase) (HST) (ST2) (ST2A3) (Sulfotransferase 2A1) (ST2A1) | Cytoplasm. | ||
| 2-5A-dependent ribonuclease (2-5A-dependent RNase) (EC 3.1.26.-) (Ribonuclease 4) (Ribonuclease L) (RNase L) | Cytoplasm | ||
| Transcription initiation factor IIA subunit 2 (General transcription factor IIA subunit 2) (TFIIA p12 subunit) (TFIIA-12) (TFIIAS) (Transcription initiation factor IIA gamma chain) (TFIIA-gamma) | Nucleus. | ||
| Paired box protein Pax-6 (Aniridia type II protein) (Oculorhombin) | Nucleus. | ||
| Fos-related antigen 2 (FRA-2) | Nucleus. | ||
| Myocyte-specific enhancer factor 2D | Nucleus | ||
| Mitoguardin 2 (Protein FAM73B) | Mitochondrion outer membrane | ||
| Homeobox protein DLX-4 (Beta protein 1) (Homeobox protein DLX-7) (Homeobox protein DLX-8) | Nucleus | ||
| Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit) | Nucleus. | ||
| Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (TATA-binding protein-associated phosphoprotein) | Nucleus. | ||
| Zinc finger protein ZPR1 (Zinc finger protein 259) | Nucleus | ||
| Dynamin-1 (EC 3.6.5.5) | Cytoplasm | ||
| Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like) | Cytoplasm, cytoskeleton | ||
| WAS/WASL-interacting protein family member 2 (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein) (WIP-related protein) | Cytoplasm, cytoskeleton | ||
| tRNA-splicing endonuclease subunit Sen34 (EC 4.6.1.16) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34) | pontocerebellar hypoplasia | Nucleus | |
| Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1) | |||
| Wiskott-Aldrich syndrome protein family member 1 (WASP family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1) | Cytoplasm, cytoskeleton | ||
| Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand) (APTL) (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)] | Cell membrane | ||
| Protein enabled homolog | Cytoplasm | ||
| LIM/homeobox protein Lhx3 (LIM homeobox protein 3) | Nucleus | ||
| Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2) | Nucleus | ||
| Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPS synthase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK 1) (SK1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)] | |||
| DNA methyltransferase 1-associated protein 1 (DNMAP1) (DNMT1-associated protein 1) | |||
| B9 domain-containing protein 2 (MKS1-related protein 2) | autosomal recessive cerebellar ataxia | Cytoplasm, cytoskeleton, cilium basal body | |
| PCNA-associated factor (Hepatitis C virus NS5A-transactivated protein 9) (HCV NS5A-transactivated protein 9) (Overexpressed in anaplastic thyroid carcinoma 1) (OEATC-1) (PCNA-associated factor of 15 kDa) (PAF15) (p15PAF) (PCNA-clamp-associated factor) | Nucleus | ||
| Wilms tumor protein (WT33) | multiple sclerosis | Nucleus | |
| DNA polymerase delta subunit 3 (DNA polymerase delta subunit C) (DNA polymerase delta subunit p66) (DNA polymerase delta subunit p68) | Cytoplasm | ||
| Histone-lysine N-methyltransferase SETD7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase SETD7) (H3-K4-HMTase SETD7) (Lysine N-methyltransferase 7) (SET domain-containing protein 7) (SET7/9) | Nucleus | ||
| Retrotransposon Gag-like protein 8B (Mammalian retrotransposon derived protein 8B) | |||
| 55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) | Cell membrane | ||
| Keratin, type II cuticular Hb2 (Keratin-82) (K82) (Type II hair keratin Hb2) (Type-II keratin Kb22) | |||
| TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160) | Cytoplasm | ||
| 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (EC 3.2.2.-) (c-Myc-responsive protein RCL) | Cytoplasm | ||
| 5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog) | Cytoplasm | ||
| Neurogranin (Ng) (RC3) [Cleaved into: NEUG(55-78)] | |||
| Keratin-associated protein 10-4 (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4) | |||
| Gamma-parvin | Cell junction, focal adhesion | ||
| Double C2-like domain-containing protein beta (Doc2-beta) | lateral sclerosis | Cytoplasm | |
| Double C2-like domain-containing protein alpha (Doc2) (Doc2-alpha) | Lysosome | ||
| Synaptotagmin-16 (Chr14Syt) (Synaptotagmin 14-like protein) (Synaptotagmin XIV-related protein) | |||
| Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR) | |||
| Inactive hydroxysteroid dehydrogenase-like protein 1 (Short chain dehydrogenase/reductase family 12C member 3) | Mitochondrion | ||
| Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas) | Cell junction, focal adhesion | ||
| Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP) | Cytoplasm | ||
| Enhancer of filamentation 1 (hEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (Cas scaffolding protein family member 2) (Neural precursor cell expressed developmentally down-regulated protein 9) (NEDD-9) (Renal carcinoma antigen NY-REN-12) (p105) [Cleaved into: Enhancer of filamentation 1 p55] | |||
| Leucine-rich repeat and calponin homology domain-containing protein 4 (Leucine-rich repeat neuronal protein 4) (Leucine-rich neuronal protein) | |||
| PIH1 domain-containing protein 1 (Nucleolar protein 17 homolog) | |||
| MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Phostensin (Protein phosphatase 1 F-actin cytoskeleton-targeting subunit) (Protein phosphatase 1 regulatory subunit 18) | Isoform 1: Cytoplasm, cytoskeleton | ||
| Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3) | lateral sclerosis amyotrophic lateral sclerosis | Endosome membrane | |
| Regulator of microtubule dynamics protein 2 (RMD-2) (hRMD-2) (Protein FAM82A1) | Membrane | ||
| Vasorin (Protein slit-like 2) | Membrane | ||
| Ribonuclease T2 (EC 3.1.27.-) (Ribonuclease 6) | |||
| E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) (HECT-type E3 ubiquitin transferase HECTD1) | |||
| Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen 1 (FA1)] | Membrane | ||
| Egl nine homolog 3 (EC 1.14.11.29) (HPH-1) (Hypoxia-inducible factor prolyl hydroxylase 3) (HIF-PH3) (HIF-prolyl hydroxylase 3) (HPH-3) (Prolyl hydroxylase domain-containing protein 3) (PHD3) | |||
| Polyadenylate-binding protein 3 (PABP-3) (Poly(A)-binding protein 3) (Testis-specific poly(A)-binding protein) | Cytoplasm | ||
| MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78) | Cell membrane | ||
| 28S ribosomal protein S29, mitochondrial (MRP-S29) (S29mt) (Death-associated protein 3) (DAP-3) (Ionizing radiation resistance conferring protein) (Mitochondrial small ribosomal subunit protein mS29) | Mitochondrion | ||
| Ribosome maturation protein SBDS (Shwachman-Bodian-Diamond syndrome protein) | |||
| Uncharacterized protein C14orf119 | Mitochondrion | ||
| Contactin-1 (Glycoprotein gp135) (Neural cell surface protein F3) | Isoform 1: Cell membrane | ||
| Ankyrin-3 (ANK-3) (Ankyrin-G) | autism spectrum disorder | Cytoplasm, cytoskeleton | |
| Homeobox protein Hox-B5 (Homeobox protein HHO.C10) (Homeobox protein Hox-2A) (Homeobox protein Hu-1) | Nucleus. | ||
| Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor) | Nucleus | ||
| Ectodysplasin-A receptor-associated adapter protein (EDAR-associated death domain protein) (Protein crinkled homolog) | Cytoplasm | ||
| Patatin-like phospholipase domain-containing protein 1 (EC 3.1.1.-) | Cytoplasm | ||
| Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] | Notch 2 extracellular truncation: Cell membrane | ||
| StAR-related lipid transfer protein 13 (46H23.2) (Deleted in liver cancer 2 protein) (DLC-2) (Rho GTPase-activating protein) (START domain-containing protein 13) (StARD13) | Cytoplasm | ||
| Serum response factor (SRF) | Nucleus | ||
| Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (hBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) | Cell membrane | ||
| Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171) | Cell membrane | ||
| Small integral membrane protein 19 | Membrane | ||
| Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14) | Nucleus | ||
| Helicase ARIP4 (EC 3.6.4.12) (Androgen receptor-interacting protein 4) (RAD54-like protein 2) | Nucleus | ||
| Cyclin N-terminal domain-containing protein 1 | |||
| Contactin-associated protein-like 3 (Cell recognition molecule Caspr3) | Isoform 1: Cell membrane | ||
| Sialate O-acetylesterase (EC 3.1.1.53) (H-Lse) (Sialic acid-specific 9-O-acetylesterase) | multiple sclerosis | Lysosome | |
| Sushi domain-containing protein 4 | Isoform 1: Membrane | ||
| Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) | |||
| N-acylethanolamine-hydrolyzing acid amidase (EC 3.5.1.-) (Acid ceramidase-like protein) (N-acylsphingosine amidohydrolase-like) (ASAH-like protein) [Cleaved into: N-acylethanolamine-hydrolyzing acid amidase subunit alpha; N-acylethanolamine-hydrolyzing acid amidase subunit beta] | Lysosome | ||
| Tafazzin (Protein G4.5) | Isoform 1: Membrane | ||
| Uncharacterized protein C1orf122 (Protein ALAESM) | |||
| Collagen alpha-1(II) chain (Alpha-1 type II collagen) [Cleaved into: Collagen alpha-1(II) chain; Chondrocalcin] | Secreted, extracellular space, extracellular matrix | ||
| Polycystin-1 (PC1) (Autosomal dominant polycystic kidney disease 1 protein) | Cell membrane | ||
| Annexin A5 (Anchorin CII) (Annexin V) (Annexin-5) (Calphobindin I) (CBP-I) (Endonexin II) (Lipocortin V) (Placental anticoagulant protein 4) (PP4) (Placental anticoagulant protein I) (PAP-I) (Thromboplastin inhibitor) (Vascular anticoagulant-alpha) (VAC-alpha) | |||
| Protein SSX4 (Cancer/testis antigen 5.4) (CT5.4) | |||
| Cochlin (COCH-5B2) | Secreted, extracellular space, extracellular matrix | ||
| Integrin alpha-IIb (GPalpha IIb) (GPIIb) (Platelet membrane glycoprotein IIb) (CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2] | Membrane | ||
| Collagen alpha-2(IV) chain [Cleaved into: Canstatin] | Secreted, extracellular space, extracellular matrix, basement membrane. | ||
| Transmembrane protein 25 | Isoform 1: Cell membrane | ||
| Semenogelin-1 (Cancer/testis antigen 103) (Semenogelin I) (SGI) [Cleaved into: Alpha-inhibin-92; Alpha-inhibin-31; Seminal basic protein] | Secreted. | ||
| Starch-binding domain-containing protein 1 (Genethonin-1) (Glycophagy cargo receptor STBD1) | Preautophagosomal structure membrane | ||
| Complement C1q subcomponent subunit B | Secreted. | ||
| Chymotrypsin-like elastase family member 2B (EC 3.4.21.71) (Elastase-2B) | Secreted. | ||
| Acid-sensing ion channel 1 (ASIC1) (Amiloride-sensitive cation channel 2, neuronal) (Brain sodium channel 2) (BNaC2) | Cell membrane | ||
| Prefoldin subunit 4 (Protein C-1) | Nucleus | ||
| GPI transamidase component PIG-T (Phosphatidylinositol-glycan biosynthesis class T protein) | Endoplasmic reticulum membrane | ||
| Deubiquitinating protein VCIP135 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135) (VCP/p47 complex-interacting 135-kDa protein) | Endoplasmic reticulum | ||
| Triple functional domain protein (EC 2.7.11.1) (PTPRF-interacting protein) | Cytoplasm | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (Complex I-MWFE) (CI-MWFE) (NADH-ubiquinone oxidoreductase MWFE subunit) | Parkinson disease | Mitochondrion inner membrane | |
| Protein capicua homolog | Nucleus | ||
| Lipoyltransferase 1, mitochondrial (EC 2.3.1.-) (Lipoate biosynthesis protein) (Lipoate-protein ligase) (Lipoyl ligase) | Mitochondrion. | ||
| Zinc finger protein 268 (Zinc finger protein HZF3) | Isoform 1: Nucleus | ||
| TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) | |||
| Transcription elongation factor A protein 2 (Testis-specific S-II) (Transcription elongation factor S-II protein 2) (Transcription elongation factor TFIIS.l) | Nucleus. | ||
| Beta-synuclein | Cytoplasm. | ||
| Protein FAM9B | Nucleus | ||
| Probable E3 ubiquitin-protein ligase TRIML2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIML2) (SPRY domain-containing protein 6) (Tripartite motif family-like protein 2) | |||
| S1 RNA-binding domain-containing protein 1 | |||
| Transcription factor SOX-3 | Nucleus. | ||
| H/ACA ribonucleoprotein complex subunit 1 (Nucleolar protein family A member 1) (snoRNP protein GAR1) | |||
| Myb/SANT-like DNA-binding domain-containing protein 4 (Myb/SANT-like DNA-binding domain containing 4 with coiled-coils) | |||
| Putative inactive beta-glucuronidase-like protein SMA3 | spinal muscular atrophy | ||
| MOB kinase activator 2 (HCCA2) (Mob2 homolog) (Mps one binder kinase activator-like 2) | Nucleus | ||
| Chromosome-associated kinesin KIF4B (Chromokinesin-B) | Nucleus matrix | ||
| Putative oxidoreductase GLYR1 (EC 1.-.-.-) (3-hydroxyisobutyrate dehydrogenase-like protein) (Cytokine-like nuclear factor N-PAC) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60) (Nuclear protein of 60 kDa) | Nucleus | ||
| Genetic suppressor element 1 | |||
| Uncharacterized protein C1orf94 | |||
| Neuroplastin (Stromal cell-derived receptor 1) (SDR-1) | Cell membrane | ||
| Glucagon-like peptide 1 receptor (GLP-1 receptor) (GLP-1-R) (GLP-1R) | Cell membrane | ||
| Centrosomal protein of 57 kDa (Cep57) (FGF2-interacting protein) (Testis-specific protein 57) (Translokin) | Nucleus | ||
| Serpin I2 (Myoepithelium-derived serine protease inhibitor) (Pancpin) (Pancreas-specific protein TSA2004) (Peptidase inhibitor 14) (PI-14) | Secreted | ||
| Desmocollin-1 (Cadherin family member 1) (Desmosomal glycoprotein 2/3) (DG2/DG3) | Cell membrane | ||
| Centrosomal protein of 63 kDa (Cep63) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Ferritin heavy chain (Ferritin H subunit) (EC 1.16.3.1) (Cell proliferation-inducing gene 15 protein) [Cleaved into: Ferritin heavy chain, N-terminally processed] | |||
| Ferritin light chain (Ferritin L subunit) | episodic ataxia | ||
| RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein) | Cytoplasm | ||
| RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (Ral-interacting protein 1) | Membrane | ||
| U6 snRNA-associated Sm-like protein LSm3 | Nucleus | ||
| Carcinoembryonic antigen-related cell adhesion molecule 1 (Biliary glycoprotein 1) (BGP-1) (CD antigen CD66a) | Isoform 1: Cell membrane | ||
| Protein PRRC2C (BAT2 domain-containing protein 1) (HBV X-transactivated gene 2 protein) (HBV XAg-transactivated protein 2) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C) | |||
| Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2) | Cytoplasm, cytoskeleton, spindle | ||
| Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.4.19.12) (Deubiquitinating enzyme 43) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) | |||
| Gastrin [Cleaved into: Gastrin-71 (Gastrin component I); Gastrin-52 (G52); Big gastrin (Gastrin component II) (Gastrin-34) (G34); Gastrin (Gastrin component III) (Gastrin-17) (G17); Gastrin-14 (G14); Gastrin-6 (G6)] | Secreted. | ||
| Cyclin-dependent kinase 20 (EC 2.7.11.22) (CDK-activating kinase p42) (CAK-kinase p42) (Cell cycle-related kinase) (Cell division protein kinase 20) (Cyclin-dependent protein kinase H) (Cyclin-kinase-activating kinase p42) | Nucleus | ||
| CLK4-associating serine/arginine rich protein (Splicing factor, arginine/serine-rich 16) (Suppressor of white-apricot homolog 2) | Nucleus | ||
| ADP-ribosylation factor-like protein 2-binding protein (ARF-like 2-binding protein) (ARL2-binding protein) (Binder of ARF2 protein 1) | |||
| 28S ribosomal protein S28, mitochondrial (MRP-S28) (S28mt) (28S ribosomal protein S35, mitochondrial) (MRP-S35) (S35mt) (Mitochondrial small ribosomal subunit protein bS1m) | Mitochondrion | ||
| Zinc finger protein 644 (Zinc finger motif enhancer-binding protein 2) (Zep-2) | Nucleus. | ||
| Ras-related protein Rab-7L1 (Rab-7-like protein 1) (Ras-related protein Rab-29) | Cell membrane | ||
| MAGE-like protein 2 (Necdin-like protein 1) (Protein nM15) | autism spectrum disorder | Early endosome | |
| Eukaryotic translation elongation factor 1 epsilon-1 (Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3) (Elongation factor p18) (Multisynthase complex auxiliary component p18) | Cytoplasm | ||
| Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41) (p12A) | Cytoplasm | ||
| Putative Wilms tumor upstream neighbor 1 gene protein (WIT-1) (Wilms tumor-associated antisense RNA) | |||
| Chromodomain-helicase-DNA-binding protein 5 (CHD-5) (EC 3.6.4.12) (ATP-dependent helicase CHD5) | Nucleus | ||
| Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.12) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1) | autism spectrum disorder | Nucleus | |
| Solute carrier family 15 member 3 (Osteoclast transporter) (Peptide transporter 3) (Peptide/histidine transporter 2) | Lysosome membrane | ||
| Pleckstrin homology domain-containing family N member 1 (PH domain-containing family N member 1) (Cardiolipin and phosphatidic acid-binding protein) | Cell membrane | ||
| Ras-related protein Rab-4B | Cell membrane | ||
| Speriolin-like protein (Spermatogenesis and centriole-associated protein 1-like protein) | |||
| Extracellular calcium-sensing receptor (CaR) (CaSR) (hCasR) (Parathyroid cell calcium-sensing receptor 1) (PCaR1) | Cell membrane | ||
| Syntaxin-10 (Syn10) | Golgi apparatus membrane | ||
| Ret finger protein-like 4B (RING finger protein 211) | |||
| Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog) | Nucleus, nucleoplasm | ||
| Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7) | Isoform 1: Nucleus | ||
| RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase) | multiple system atrophy | Nucleus | |
| Zinc finger protein 143 (SPH-binding factor) (Selenocysteine tRNA gene transcription-activating factor) (hStaf) | Nucleus | ||
| Twinkle protein, mitochondrial (EC 3.6.4.12) (Progressive external ophthalmoplegia 1 protein) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Twinkle mtDNA helicase) | Mitochondrion matrix, mitochondrion nucleoid | ||
| Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1) | Mitochondrion inner membrane | ||
| Seizure protein 6 homolog (SEZ-6) (hSEZ-6) | Cell membrane | ||
| Acyl-CoA dehydrogenase family member 9, mitochondrial (ACAD-9) (EC 1.3.99.-) | Mitochondrion | ||
| Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form] | autosomal recessive cerebellar ataxia primary cerebellar degeneration autosomal dominant cerebellar ataxia ... multiple system atrophy | Lysosome. | |
| Bloom syndrome protein (EC 3.6.4.12) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3) | Nucleus | ||
| Nuclear fragile X mental retardation-interacting protein 2 (82 kDa FMRP-interacting protein) (82-FIP) (Cell proliferation-inducing gene 1 protein) (FMRP-interacting protein 2) | Nucleus | ||
| Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6) | Cell membrane | ||
| Arfaptin-1 (ADP-ribosylation factor-interacting protein 1) | |||
| Sperm protein associated with the nucleus on the X chromosome D (Cancer/testis antigen 11.4) (CT11.4) (Nuclear-associated protein SPAN-Xd) (SPANX-D) (SPANX family member D) | Cytoplasm | ||
| Zinc finger protein 318 (Endocrine regulatory protein) | Nucleus | ||
| Protein SSX1 (Cancer/testis antigen 5.1) (CT5.1) (Synovial sarcoma, X breakpoint 1) | |||
| Synergin gamma (AP1 subunit gamma-binding protein 1) (Gamma-synergin) | Cytoplasm | ||
| GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1) | |||
| Adhesion G protein-coupled receptor B2 (Brain-specific angiogenesis inhibitor 2) | Cell membrane | ||
| Centrin-2 (Caltractin isoform 1) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Apoptosis-associated speck-like protein containing a CARD (hASC) (Caspase recruitment domain-containing protein 5) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) | |||
| D(1A) dopamine receptor (Dopamine D1 receptor) | Cell membrane | ||
| Sepiapterin reductase (SPR) (EC 1.1.1.153) | Cytoplasm. | ||
| D(2) dopamine receptor (Dopamine D2 receptor) | Cell membrane | ||
| LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1) (hLim-1) | Nucleus | ||
| Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N) | Cytoplasm, cytoskeleton. | ||
| Sodium-dependent dopamine transporter (DA transporter) (DAT) (Solute carrier family 6 member 3) | Cell membrane | ||
| Collagen alpha-1(XXIII) chain | Cell membrane | ||
| Tumor necrosis factor receptor superfamily member 18 (Activation-inducible TNFR family receptor) (Glucocorticoid-induced TNFR-related protein) (CD antigen CD357) | Isoform 1: Cell membrane | ||
| E3 ubiquitin-protein ligase AMFR (EC 2.3.2.27) (Autocrine motility factor receptor) (AMF receptor) (RING finger protein 45) (RING-type E3 ubiquitin transferase AMFR) (gp78) | Endoplasmic reticulum membrane | ||
| Cytosolic 5'-nucleotidase 3A (EC 3.1.3.5) (7-methylguanosine phosphate-specific 5'-nucleotidase) (7-methylguanosine nucleotidase) (EC 3.1.3.91) (Cytosolic 5'-nucleotidase 3) (Cytosolic 5'-nucleotidase III) (cN-III) (Pyrimidine 5'-nucleotidase 1) (P5'N-1) (P5N-1) (PN-I) (Uridine 5'-monophosphate hydrolase 1) (p36) | Cytoplasm | ||
| Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B) | Cytoplasm | ||
| Protein FAM162A (E2-induced gene 5 protein) (Growth and transformation-dependent protein) (HGTD-P) | Membrane | ||
| Calcium uptake protein 1, mitochondrial (Atopy-related autoantigen CALC) (ara CALC) (Calcium-binding atopy-related autoantigen 1) (allergen Hom s 4) | Mitochondrion inner membrane | ||
| Myeloid-derived growth factor (MYDGF) | Secreted | ||
| Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6) (Stress-activated protein kinase kinase 3) (SAPK kinase 3) (SAPKK-3) (SAPKK3) | Nucleus | ||
| Transmembrane protein 11, mitochondrial (Protein PM1) (Protein PMI) | Mitochondrion inner membrane | ||
| Transmembrane protein 218 | Membrane | ||
| Zinc transporter 8 (ZnT-8) (Solute carrier family 30 member 8) | Cell membrane | ||
| Protein jagunal homolog 1 | Endoplasmic reticulum membrane | ||
| Protein FAM3C (Interleukin-like EMT inducer) | Secreted | ||
| FXYD domain-containing ion transport regulator 6 (Phosphohippolin) | Membrane | ||
| NF-kappa-B inhibitor delta (I-kappa-B-delta) (IkB-delta) (IkappaBdelta) (IkappaBNS) (T-cell activation NFKB-like protein) (TA-NFKBH) | Nucleus | ||
| Transmembrane protein 128 | Membrane | ||
| Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog) (hsMOT2) | Cell membrane | ||
| UDP-xylose and UDP-N-acetylglucosamine transporter (Solute carrier family 35 member B4) (YEA4 homolog) | Golgi apparatus membrane | ||
| Transmembrane protein 147 (Protein NIFIE 14) | Endoplasmic reticulum membrane | ||
| Transcription and mRNA export factor ENY2 (Enhancer of yellow 2 transcription factor homolog) | Nucleus, nucleoplasm | ||
| Extracellular sulfatase Sulf-1 (hSulf-1) (EC 3.1.6.-) | Endoplasmic reticulum | ||
| Ataxin-7-like protein 3 (SAGA-associated factor 11 homolog) | Nucleus | ||
| SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1) | Nucleus inner membrane | ||
| Transcription initiation factor TFIID subunit 10 (STAF28) (Transcription initiation factor TFIID 30 kDa subunit) (TAF(II)30) (TAFII-30) (TAFII30) | Nucleus | ||
| Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21) | Cytoplasm | ||
| Lactotransferrin (Lactoferrin) (EC 3.4.21.-) (Growth-inhibiting protein 12) (Talalactoferrin) [Cleaved into: Lactoferricin-H (Lfcin-H); Kaliocin-1; Lactoferroxin-A; Lactoferroxin-B; Lactoferroxin-C] | |||
| Keratin, type I cuticular Ha5 (Hair keratin, type I Ha5) (Keratin-35) (K35) | |||
| Epsin-2 (EPS-15-interacting protein 2) | Cytoplasm | ||
| AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Huntingtin yeast partner J) (Huntingtin-interacting protein 9) (HIP-9) (Huntingtin-interacting protein J) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) | Cell membrane | ||
| Junctophilin-3 (JP-3) (Junctophilin type 3) (Trinucleotide repeat-containing gene 22 protein) | Huntington disease | Cell membrane | |
| Spartin (Spastic paraplegia 20 protein) (Trans-activated by hepatitis C virus core protein 1) | Cytoplasm | ||
| UV excision repair protein RAD23 homolog A (HR23A) (hHR23A) | Nucleus. | ||
| Stonin-2 (Stoned B) | Cytoplasm | ||
| Submaxillary gland androgen-regulated protein 3B (Proline-rich peptide P-B) (Proline-rich protein 3) [Cleaved into: Peptide P-A; Peptide D1A] | Secreted. | ||
| RING finger protein 11 | Parkinson disease | ||
| Lipocalin-1 (Tear lipocalin) (Tlc) (Tear prealbumin) (TP) (von Ebner gland protein) (VEG protein) | Secreted. | ||
| BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1) | Nucleus | ||
| Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3) | |||
| Zinc finger protein 624 | Nucleus | ||
| Arf-GAP domain and FG repeat-containing protein 1 (HIV-1 Rev-binding protein) (Nucleoporin-like protein RIP) (Rev-interacting protein) (Rev/Rex activation domain-binding protein) | Nucleus | ||
| Interferon alpha-5 (IFN-alpha-5) (Interferon alpha-61) (Interferon alpha-G) (LeIF G) | Secreted. | ||
| Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK) | Cell membrane | ||
| Kallikrein-10 (EC 3.4.21.-) (Normal epithelial cell-specific 1) (Protease serine-like 1) | Secreted | ||
| Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein) | Cytoplasm | ||
| Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2) | lateral sclerosis amyotrophic lateral sclerosis | Cytoplasm | |
| Keratin, type II cuticular Hb3 (Hair keratin K2.10) (Keratin-83) (K83) (Type II hair keratin Hb3) (Type-II keratin Kb23) | |||
| U7 snRNA-associated Sm-like protein LSm10 | Nucleus | ||
| Transmembrane protein 9 (Dermal papilla-derived protein 4) | Late endosome membrane | ||
| Protein numb homolog (h-Numb) (Protein S171) | Membrane | ||
| F-BAR domain only protein 2 | Membrane, clathrin-coated pit | ||
| Keratin, type I cuticular Ha4 (Hair keratin, type I Ha4) (Keratin-34) (K34) | |||
| Lumican (Keratan sulfate proteoglycan lumican) (KSPG lumican) | lateral sclerosis multiple sclerosis | Secreted, extracellular space, extracellular matrix | |
| Keratin, type I cytoskeletal 17 (39.1) (Cytokeratin-17) (CK-17) (Keratin-17) (K17) | Cytoplasm | ||
| Clathrin coat assembly protein AP180 (91 kDa synaptosomal-associated protein) (Clathrin coat-associated protein AP180) (Phosphoprotein F1-20) | Cell membrane | ||
| Oligodendrocyte transcription factor 3 (Oligo3) (Class B basic helix-loop-helix protein 7) (bHLHb7) (Class E basic helix-loop-helix protein 20) (bHLHe20) | Nucleus | ||
| Keratin, type I cuticular Ha7 (Hair keratin, type I Ha7) (Keratin-37) (K37) | |||
| Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) | Cytoplasm | ||
| Pre-B-cell leukemia transcription factor 3 (Homeobox protein PBX3) | Nucleus | ||
| Numb-like protein (Numb-related protein) (Numb-R) | Cytoplasm | ||
| ADP-ribosylation factor-binding protein GGA2 (Gamma-adaptin-related protein 2) (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear) | Golgi apparatus, trans-Golgi network membrane | ||
| Homeobox protein ARX (Aristaless-related homeobox) | Nucleus | ||
| Tektin-3 | Cell projection, cilium, flagellum | ||
| Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1) (Rab-3-interacting protein 2) | Cell membrane | ||
| Protein piccolo (Aczonin) | pontocerebellar hypoplasia | Cell junction, synapse | |
| Dipeptidase 2 (EC 3.4.13.19) | Membrane | ||
| Single-pass membrane and coiled-coil domain-containing protein 4 (Protein FN5) | Membrane | ||
| ERI1 exoribonuclease 2 (EC 3.1.-.-) (Exonuclease domain-containing protein 1) | |||
| Endoplasmic reticulum-Golgi intermediate compartment protein 3 (Serologically defined breast cancer antigen NY-BR-84) | Endoplasmic reticulum-Golgi intermediate compartment membrane | ||
| Erlin-1 (Endoplasmic reticulum lipid raft-associated protein 1) (Protein KE04) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1) (SPFH domain-containing protein 1) | Endoplasmic reticulum membrane | ||
| Insulin-induced gene 1 protein (INSIG-1) | Endoplasmic reticulum membrane | ||
| E3 ubiquitin-protein ligase synoviolin (EC 2.3.2.27) (RING-type E3 ubiquitin transferase synoviolin) (Synovial apoptosis inhibitor 1) | Endoplasmic reticulum membrane | ||
| Erythrocyte band 7 integral membrane protein (Protein 7.2b) (Stomatin) | Cell membrane | ||
| Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor) | autosomal dominant cerebellar ataxia | Endoplasmic reticulum membrane | |
| Vesicle-trafficking protein SEC22a (SEC22 vesicle-trafficking protein homolog A) (SEC22 vesicle-trafficking protein-like 2) | Endoplasmic reticulum membrane | ||
| Arylsulfatase K (ASK) (EC 3.1.6.-) (Telethon sulfatase) | Secreted | ||
| Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein) | Endoplasmic reticulum membrane | ||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34) | Endoplasmic reticulum membrane | ||
| Prolyl endopeptidase FAP (EC 3.4.21.26) (170 kDa melanoma membrane-bound gelatinase) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)] | Prolyl endopeptidase FAP: Cell surface | ||
| Ubiquitin-like protein 4A (Ubiquitin-like protein GDX) | Cytoplasm, cytosol | ||
| Peptidyl-prolyl cis-trans isomerase FKBP14 (PPIase FKBP14) (EC 5.2.1.8) (22 kDa FK506-binding protein) (22 kDa FKBP) (FKBP-22) (FK506-binding protein 14) (FKBP-14) (Rotamase) | Endoplasmic reticulum lumen | ||
| Nicastrin | Membrane | ||
| Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter) | Cytoplasm | ||
| Thioredoxin domain-containing protein 12 (EC 1.8.4.2) (Endoplasmic reticulum resident protein 18) (ER protein 18) (ERp18) (Endoplasmic reticulum resident protein 19) (ER protein 19) (ERp19) (Thioredoxin-like protein p19) (hTLP19) | Endoplasmic reticulum lumen | ||
| Gamma-secretase subunit PEN-2 (Presenilin enhancer protein 2) | Endoplasmic reticulum membrane | ||
| Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1] | Endoplasmic reticulum membrane | ||
| Cadherin-4 (Retinal cadherin) (R-CAD) (R-cadherin) | Cell membrane | ||
| Mitochondrial Rho GTPase 1 (MIRO-1) (hMiro-1) (EC 3.6.5.-) (Rac-GTP-binding protein-like protein) (Ras homolog gene family member T1) | Mitochondrion outer membrane | ||
| Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2) | Cytoplasm, cytoskeleton. | ||
| Amphoterin-induced protein 1 (AMIGO-1) (Alivin-2) | Cell membrane | ||
| Gamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha) (Presenilin-stabilization factor) | Endoplasmic reticulum membrane | ||
| Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1) | Endoplasmic reticulum membrane | ||
| Ubiquitin recognition factor in ER-associated degradation protein 1 (Ubiquitin fusion degradation protein 1) (UB fusion protein 1) | Nucleus | ||
| Erythroid membrane-associated protein (hERMAP) (Radin blood group antigen) (Scianna blood group antigen) | Cell membrane | ||
| Serpin B3 (Protein T4-A) (Squamous cell carcinoma antigen 1) (SCCA-1) | Cytoplasm | ||
| N-arachidonyl glycine receptor (NAGly receptor) (G-protein coupled receptor 18) | Cell membrane | ||
| Arginase-1 (EC 3.5.3.1) (Liver-type arginase) (Type I arginase) | spastic ataxia | Cytoplasm | |
| Serpin B5 (Maspin) (Peptidase inhibitor 5) (PI-5) | Secreted, extracellular space. | ||
| Mannose-binding protein C (MBP-C) (Collectin-1) (MBP1) (Mannan-binding protein) (Mannose-binding lectin) | Secreted | ||
| Epidermal growth factor receptor kinase substrate 8-like protein 1 (EPS8-like protein 1) (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-related protein 1) | Cytoplasm | ||
| Son of sevenless homolog 1 (SOS-1) | |||
| Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8-like protein 2) (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-related protein 2) | Cytoplasm | ||
| Neuroglobin | Perikaryon | ||
| Epidermal growth factor receptor kinase substrate 8-like protein 3 (EPS8-like protein 3) (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-related protein 3) | Cytoplasm | ||
| PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80) | Nucleus | ||
| Histone deacetylase 4 (HD4) (EC 3.5.1.98) | autism spectrum disorder | ||
| Putative apolipoprotein(a)-like protein 2 (Apo(a)-like protein 2) (Lp(a)-liker protein 2) (Apolipoprotein a-related gene C protein) (Apo(a)rg-C) | Secreted | ||
| Ester hydrolase C11orf54 (EC 3.1.-.-) | Nucleus | ||
| Protein phosphatase 1D (EC 3.1.3.16) (Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1) | autism spectrum disorder | Nucleus | |
| RB1-inducible coiled-coil protein 1 (FAK family kinase-interacting protein of 200 kDa) (FIP200) | Nucleus | ||
| Angiogenin (EC 3.1.27.-) (Ribonuclease 5) (RNase 5) | lateral sclerosis amyotrophic lateral sclerosis | Cytoplasmic vesicle, secretory vesicle lumen | |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2) | |||
| Granzyme A (EC 3.4.21.78) (CTL tryptase) (Cytotoxic T-lymphocyte proteinase 1) (Fragmentin-1) (Granzyme-1) (Hanukkah factor) (H factor) (HF) | Isoform alpha: Secreted | ||
| Retinal dehydrogenase 2 (RALDH 2) (RalDH2) (EC 1.2.1.36) (Aldehyde dehydrogenase family 1 member A2) (Retinaldehyde-specific dehydrogenase type 2) (RALDH(II)) | Cytoplasm. | ||
| Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP) | |||
| Granzyme B (EC 3.4.21.79) (C11) (CTLA-1) (Cathepsin G-like 1) (CTSGL1) (Cytotoxic T-lymphocyte proteinase 2) (Lymphocyte protease) (Fragmentin-2) (Granzyme-2) (Human lymphocyte protein) (HLP) (SECT) (T-cell serine protease 1-3E) | Cytoplasmic granule | ||
| Ubiquitin conjugation factor E4 A (EC 2.3.2.27) (RING-type E3 ubiquitin transferase E4 A) | Cytoplasm | ||
| BH3-interacting domain death agonist (p22 BID) (BID) [Cleaved into: BH3-interacting domain death agonist p15 (p15 BID); BH3-interacting domain death agonist p13 (p13 BID); BH3-interacting domain death agonist p11 (p11 BID)] | Cytoplasm | ||
| CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains) | Cytoplasm, cytoskeleton | ||
| Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.4.19.12) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y-linked) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific protease 9, Y chromosome) (Ubiquitin-specific-processing protease FAF-Y) | Cytoplasm | ||
| Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)] | autosomal recessive cerebellar ataxia | Nucleus | |
| GRAM domain-containing protein 4 (Death-inducing protein) | Mitochondrion membrane | ||
| Tubulinyl-Tyr carboxypeptidase 2 (EC 3.4.17.17) (Vasohibin-2) (Vasohibin-like protein) | Cytoplasm | ||
| GRB2-related adapter protein 2 (Adapter protein GRID) (GRB-2-like protein) (GRB2L) (GRBLG) (GRBX) (Grf40 adapter protein) (Grf-40) (Growth factor receptor-binding protein) (Hematopoietic cell-associated adapter protein GrpL) (P38) (Protein GADS) (SH3-SH2-SH3 adapter Mona) | Nucleus | ||
| Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76) | Cytoplasm | ||
| Son of sevenless homolog 2 (SOS-2) | |||
| T-cell-specific surface glycoprotein CD28 (TP44) (CD antigen CD28) | Membrane | ||
| TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6) | |||
| ETS translocation variant 5 (Ets-related protein ERM) | Nucleus. | ||
| Junctional sarcoplasmic reticulum protein 1 (Junctional-face membrane protein of 45 kDa homolog) (JP-45) | Sarcoplasmic reticulum membrane | ||
| RAD50-interacting protein 1 (RAD50 interactor 1) (HsRINT-1) (RINT-1) | Cytoplasm | ||
| E3 ubiquitin-protein ligase CBL-B (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56) (RING-type E3 ubiquitin transferase CBL-B) (SH3-binding protein CBL-B) (Signal transduction protein CBL-B) | Cytoplasm | ||
| E3 ubiquitin-protein ligase TRIM68 (EC 2.3.2.27) (RING finger protein 137) (RING-type E3 ubiquitin transferase TRIM68) (SSA protein SS-56) (SS-56) (Tripartite motif-containing protein 68) | |||
| GRB2-related adapter protein | |||
| Coronin-2B (Coronin-like protein C) (Clipin-C) (Protein FC96) | Cytoplasm, cytoskeleton | ||
| Butyrophilin subfamily 2 member A1 | Membrane | ||
| Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25) | Mitochondrion outer membrane | ||
| Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26) | |||
| Lymphotoxin-alpha (LT-alpha) (TNF-beta) (Tumor necrosis factor ligand superfamily member 1) | |||
| Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8) | Cytoplasm, cytoskeleton, cilium basal body | ||
| Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b) | |||
| Insulin receptor substrate 1 (IRS-1) | |||
| Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4) | Mitochondrion matrix. | ||
| FAST kinase domain-containing protein 3, mitochondrial | Mitochondrion | ||
| RCC1-like G exchanging factor-like protein (RCC1-like) (Williams-Beuren syndrome chromosomal region 16 protein) | Mitochondrion membrane | ||
| 39S ribosomal protein L46, mitochondrial (L46mt) (MRP-L46) (Mitochondrial large ribosomal subunit protein mL46) (P2ECSL) | Mitochondrion | ||
| Acyl carrier protein, mitochondrial (ACP) (CI-SDAP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit) | Mitochondrion | ||
| DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a) (RPB11a) (DNA-directed RNA polymerase II subunit J-1) (RNA polymerase II 13.3 kDa subunit) | Nucleus | ||
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A) | Membrane | ||
| Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH) | Parkinson disease | ||
| Tripeptidyl-peptidase 1 (TPP-1) (EC 3.4.14.9) (Cell growth-inhibiting gene 1 protein) (Lysosomal pepstatin-insensitive protease) (LPIC) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) (TPP-I) | autosomal recessive cerebellar ataxia | Lysosome | |
| GTP-binding nuclear protein Ran (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein) | Nucleus | ||
| Rho guanine nucleotide exchange factor 10 | |||
| GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase) | Endoplasmic reticulum | ||
| Disrupted in schizophrenia 1 protein | Cytoplasm | ||
| Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) | Nucleus | ||
| Protein unc-119 homolog B | Cell projection, cilium | ||
| Far upstream element-binding protein 3 (FUSE-binding protein 3) | Nucleus | ||
| Protein-lysine methyltransferase METTL21C (EC 2.1.1.-) (Methyltransferase-like protein 21C) | Nucleus | ||
| ETS translocation variant 1 (Ets-related protein 81) | Nucleus | ||
| Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) | Cytoplasm | ||
| Interferon alpha-8 (IFN-alpha-8) (Interferon alpha-B) (LeIF B) (Interferon alpha-B2) | Secreted. | ||
| Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL) | |||
| Nuclear receptor coactivator 2 (NCoA-2) (Class E basic helix-loop-helix protein 75) (bHLHe75) (Transcriptional intermediary factor 2) (hTIF2) | Nucleus. | ||
| Protein C-ets-2 | Nucleus. | ||
| Cyclin-dependent kinase 10 (EC 2.7.11.22) (Cell division protein kinase 10) (Serine/threonine-protein kinase PISSLRE) | Cytoplasm, cytoskeleton, cilium basal body | ||
| Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (hTDP2) (EC 3.1.4.-) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase) (ETS1-associated protein 2) (ETS1-associated protein II) (EAPII) (TRAF and TNF receptor-associated protein) (Tyrosyl-RNA phosphodiesterase) (VPg unlinkase) | autosomal recessive cerebellar ataxia | ||
| IQ domain-containing protein F3 | |||
| DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (DNA-directed RNA polymerase III subunit A) (RNA polymerase III 155 kDa subunit) (RPC155) (RNA polymerase III subunit C160) | autosomal recessive cerebellar ataxia | Nucleus. | |
| Chondroitin sulfate synthase 3 (EC 2.4.1.175) (EC 2.4.1.226) (Carbohydrate synthase 2) (Chondroitin glucuronyltransferase 3) (Chondroitin synthase 2) (ChSy-2) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3) (N-acetylgalactosaminyltransferase 3) | Golgi apparatus, Golgi stack membrane | ||
| LIM domain-binding protein 3 (Protein cypher) (Z-band alternatively spliced PDZ-motif protein) | Cytoplasm, perinuclear region | ||
| Testis-specific serine/threonine-protein kinase 2 (TSK-2) (TSK2) (TSSK-2) (Testis-specific kinase 2) (EC 2.7.11.1) (DiGeorge syndrome protein G) (DGS-G) (Serine/threonine-protein kinase 22B) | Cytoplasm | ||
| Protein FAM189B (Protein COTE1) | Membrane | ||
| Zinc transporter ZIP3 (Solute carrier family 39 member 3) (Zrt- and Irt-like protein 3) (ZIP-3) | Membrane | ||
| Forkhead box protein D4-like 3 (FOXD4-like 3) | Nucleus | ||
| Nuclear envelope pore membrane protein POM 121 (Nuclear envelope pore membrane protein POM 121A) (Nucleoporin Nup121) (Pore membrane protein of 121 kDa) | Nucleus, nuclear pore complex | ||
| Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28) | Cell membrane | ||
| Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6) | Cytoplasm | ||
| Neutral cholesterol ester hydrolase 1 (NCEH) (EC 3.1.1.-) (Arylacetamide deacetylase-like 1) | Membrane | ||
| Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (Fused in glioblastoma) (PDZ protein interacting specifically with TC10) (PIST) | Cytoplasm | ||
| Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331) | |||
| Testin (TESS) | |||
| Xin actin-binding repeat-containing protein 1 (Cardiomyopathy-associated protein 1) | Cell junction | ||
| Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin) | Cytoplasm, cytoskeleton | ||
| Semaphorin-6A (Semaphorin VIA) (Sema VIA) (Semaphorin-6A-1) (SEMA6A-1) | Cell membrane | ||
| BPI fold-containing family A member 1 (Lung-specific protein X) (Nasopharyngeal carcinoma-related protein) (Palate lung and nasal epithelium clone protein) (Secretory protein in upper respiratory tracts) (Short PLUNC1) (SPLUNC1) (Tracheal epithelium-enriched protein) (Von Ebner protein Hl) | Secreted | ||
| Protein KIAA0556 | autosomal recessive cerebellar ataxia | Cytoplasm, cytoskeleton, cilium axoneme | |
| Peptidyl-prolyl cis-trans isomerase-like 1 (PPIase) (EC 5.2.1.8) (Rotamase PPIL1) | Nucleus | ||
| Inducible T-cell costimulator (Activation-inducible lymphocyte immunomediatory molecule) (CD antigen CD278) | Isoform 1: Cell membrane | ||
| tRNA pseudouridine synthase-like 1 (EC 5.4.99.-) (tRNA pseudouridylate synthase-like 1) (tRNA-uridine isomerase-like 1) | |||
| Valine--tRNA ligase, mitochondrial (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS) (Valyl-tRNA synthetase-like) | Mitochondrion | ||
| Regulation of nuclear pre-mRNA domain-containing protein 1B (Cell cycle-related and expression-elevated protein in tumor) | Nucleus | ||
| Pituitary homeobox 1 (Hindlimb-expressed homeobox protein backfoot) (Homeobox protein PITX1) (Paired-like homeodomain transcription factor 1) | Nucleus. | ||
| UPF0690 protein C1orf52 (BCL10-associated gene protein) | |||
| Coiled-coil domain-containing protein 43 | |||
| E3 ubiquitin-protein ligase RNF113A (EC 2.3.2.27) (Cwc24 homolog) (RING finger protein 113A) (Zinc finger protein 183) | Nucleus speckle | ||
| Iron-sulfur cluster co-chaperone protein HscB, mitochondrial (DnaJ homolog subfamily C member 20) (Hsc20) | Cytoplasm | ||
| G patch domain-containing protein 8 | |||
| Protein quaking (Hqk) (HqkI) | Nucleus | ||
| Insulin growth factor-like family member 1 | Secreted | ||
| ETS domain-containing protein Elk-1 | Nucleus. | ||
| Myozenin-2 (Calsarcin-1) (FATZ-related protein 2) | Cytoplasm, myofibril, sarcomere, Z line | ||
| Chymase (EC 3.4.21.39) (Alpha-chymase) (Mast cell protease I) | |||
| Transcription factor E2F8 (E2F-8) | Nucleus | ||
| Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (Methyl methanesulfonate (MMF)-inducible fragment protein 1) | Endoplasmic reticulum membrane | ||
| Formin-binding protein 4 (Formin-binding protein 30) | |||
| TNF receptor-associated factor 3 (EC 2.3.2.27) (CAP-1) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3) | Cytoplasm | ||
| Insulin-like growth factor-binding protein 6 (IBP-6) (IGF-binding protein 6) (IGFBP-6) | Secreted. | ||
| Sodium/potassium-transporting ATPase subunit beta-3 (Sodium/potassium-dependent ATPase subunit beta-3) (ATPB-3) (CD antigen CD298) | Cell membrane | ||
| DNA repair protein complementing XP-G cells (EC 3.1.-.-) (DNA excision repair protein ERCC-5) (Xeroderma pigmentosum group G-complementing protein) | Nucleus | ||
| COMM domain-containing protein 7 | Cytoplasmic vesicle | ||
| Charged multivesicular body protein 5 (Chromatin-modifying protein 5) (SNF7 domain-containing protein 2) (Vacuolar protein sorting-associated protein 60) (Vps60) (hVps60) | Cytoplasm, cytosol | ||
| Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIase F) (EC 5.2.1.8) (Cyclophilin D) (CyP-D) (CypD) (Cyclophilin F) (Mitochondrial cyclophilin) (CyP-M) (Rotamase F) | Mitochondrion matrix | ||
| Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) (Cell division cycle 2-related protein kinase 7) (CDC2-related protein kinase 7) (Cell division protein kinase 12) (hCDK12) | |||
| Rho GTPase-activating protein 45 [Cleaved into: Minor histocompatibility antigen HA-1 (mHag HA-1)] | Cytoplasm | ||
| Fructose-bisphosphate aldolase C (EC 4.1.2.13) (Brain-type aldolase) | |||
| 4-hydroxyphenylpyruvate dioxygenase-like protein (EC 1.13.-.-) (Glyoxalase domain-containing protein 1) | |||
| Cleavage stimulation factor subunit 2 tau variant (CF-1 64 kDa subunit tau variant) (Cleavage stimulation factor 64 kDa subunit tau variant) (CSTF 64 kDa subunit tau variant) (TauCstF-64) | Nucleus | ||
| Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) (LCHC1) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole | ||
| Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) (Superoxide dismutase 1) (hSod1) | lateral sclerosis amyotrophic lateral sclerosis | Cytoplasm | |
| Eukaryotic translation initiation factor 4E transporter (4E-T) (eIF4E transporter) (Eukaryotic translation initiation factor 4E nuclear import factor 1) | Cytoplasm | ||
| Histone H2B type 1-N (Histone H2B.d) (H2B/d) | Nucleus | ||
| Mediator of RNA polymerase II transcription subunit 8 (Activator-recruited cofactor 32 kDa component) (ARC32) (Mediator complex subunit 8) | Nucleus | ||
| Serine protease inhibitor Kazal-type 5 (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Cleaved into: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665] | Secreted. | ||
| Urocanate hydratase (Urocanase) (EC 4.2.1.49) (Imidazolonepropionate hydrolase) | episodic ataxia | ||
| Lysosome-associated membrane glycoprotein 1 (LAMP-1) (Lysosome-associated membrane protein 1) (CD107 antigen-like family member A) (CD antigen CD107a) | Cell membrane | ||
| Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor) (Transcription factor HMX3) | Nucleus, nucleolus | ||
| Histone H2A.J (H2a/j) | Nucleus | ||
| Protein FAM207A | |||
| Prefoldin subunit 3 (HIBBJ46) (von Hippel-Lindau-binding protein 1) (VBP-1) (VHL-binding protein 1) | |||
| Nucleoside diphosphate kinase 3 (NDK 3) (NDP kinase 3) (EC 2.7.4.6) (DR-nm23) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-H3) | |||
| Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau) | pseudobulbar palsy Parkinson disease lateral sclerosis ... multiple sclerosis multiple system atrophy Pick disease Alzheimer disease amyotrophic lateral sclerosis Lafora disease | Cytoplasm, cytosol | |
| Homeobox protein OTX1 (Orthodenticle homolog 1) | Nucleus | ||
| Angiotensinogen (Serpin A8) [Cleaved into: Angiotensin-1 (Angiotensin 1-10) (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin 1-8) (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin 2-8) (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II); Angiotensin-4 (Angiotensin 3-8) (Angiotensin IV) (Ang IV); Angiotensin 1-9; Angiotensin 1-7; Angiotensin 1-5; Angiotensin 1-4] | Secreted. | ||
| Interleukin-11 (IL-11) (Adipogenesis inhibitory factor) (AGIF) (Oprelvekin) | Secreted | ||
| Smoothelin | |||
| Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (DNA-binding protein p79PIF) (Parvovirus initiation factor p79) (PIF p79) | |||
| Insulin-like growth factor-binding protein complex acid labile subunit (ALS) | Secreted, extracellular space. | ||
| Immunoglobulin superfamily member 1 (IgSF1) (Immunoglobulin-like domain-containing protein 1) (Inhibin-binding protein) (InhBP) (Pituitary gland-specific factor 2) (p120) | autism spectrum disorder | Isoform 1: Membrane | |
| Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP-like protein) (LANP-L) | Cytoplasm | ||
| Protein Wnt-10a | Secreted, extracellular space, extracellular matrix | ||
| General transcription factor IIE subunit 1 (General transcription factor IIE 56 kDa subunit) (Transcription initiation factor IIE subunit alpha) (TFIIE-alpha) | Nucleus | ||
| Mitochondrial import receptor subunit TOM22 homolog (hTom22) (1C9-2) (Translocase of outer membrane 22 kDa subunit homolog) | Mitochondrion outer membrane | ||
| Transcription initiation factor TFIID subunit 9B (Neuronal cell death-related protein 7) (DN-7) (Transcription initiation factor TFIID subunit 9-like) (Transcription-associated factor TAFII31L) | Nucleus | ||
| Protein CDV3 homolog | Cytoplasm | ||
| Transmembrane protein 254 | Membrane | ||
| Lysosome-associated membrane glycoprotein 2 (LAMP-2) (Lysosome-associated membrane protein 2) (CD107 antigen-like family member B) (LGP-96) (CD antigen CD107b) | Cell membrane | ||
| Carbonyl reductase [NADPH] 3 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase 3) (Short chain dehydrogenase/reductase family 21C member 2) | Cytoplasm | ||
| POU domain, class 4, transcription factor 1 (Brain-specific homeobox/POU domain protein 3A) (Brain-3A) (Brn-3A) (Homeobox/POU domain protein RDC-1) (Oct-T1) | Nucleus | ||
| Carcinoembryonic antigen-related cell adhesion molecule 5 (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD antigen CD66e) | Cell membrane | ||
| Paralemmin-2 | Cell membrane | ||
| Acidic leucine-rich nuclear phosphoprotein 32 family member C (Phosphoprotein 32-related protein 1) (Tumorigenic protein pp32r1) | |||
| Integrin beta-5 | Membrane | ||
| Endothelial differentiation-related factor 1 (EDF-1) (Multiprotein-bridging factor 1) (MBF1) | |||
| Complement C1q subcomponent subunit C | Secreted. | ||
| Ataxin-3 (EC 3.4.19.12) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein) | autosomal dominant cerebellar ataxia | Nucleus matrix | |
| Myosin light chain 1/3, skeletal muscle isoform (MLC1/MLC3) (MLC1F/MLC3F) (Myosin light chain alkali 1/2) (Myosin light chain A1/A2) | |||
| Ubiquitin domain-containing protein UBFD1 (Ubiquitin-binding protein homolog) | |||
| Paired box protein Pax-9 | Nucleus. | ||
| ATP synthase mitochondrial F1 complex assembly factor 2 (ATP12 homolog) | Mitochondrion | ||
| Bcl2-associated agonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-2-like protein 8) (Bcl2-L-8) (Bcl-xL/Bcl-2-associated death promoter) (Bcl2 antagonist of cell death) | Mitochondrion outer membrane | ||
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (Complex I-MNLL) (CI-MNLL) (NADH-ubiquinone oxidoreductase MNLL subunit) | Mitochondrion inner membrane | ||
| Single-stranded DNA-binding protein 3 (Sequence-specific single-stranded-DNA-binding protein) | Nucleus | ||
| Pregnancy-specific beta-1-glycoprotein 4 (PS-beta-G-4) (PSBG-4) (Pregnancy-specific glycoprotein 4) (Pregnancy-specific beta-1-glycoprotein 9) (PS-beta-G-9) (PSBG-9) (Pregnancy-specific glycoprotein 9) | Secreted | ||
| Stress-associated endoplasmic reticulum protein 2 (Ribosome-associated membrane protein RAMP4-2) | Membrane | ||
| Syntaxin-12 | Endosome membrane | ||
| Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK) | |||
| WD repeat-containing protein 37 | |||
| Homeobox protein goosecoid | Nucleus. | ||
| Sorting nexin-30 | |||
| Telomere length and silencing protein 1 homolog (Hepatocellular carcinoma-associated antigen 59) | |||
| Homeobox protein engrailed-2 (Homeobox protein en-2) (Hu-En-2) | autism spectrum disorder | Nucleus. | |
| Protein arginine N-methyltransferase 8 (EC 2.1.1.319) (EC 2.1.1.321) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4) | Cell membrane | ||
| Talin-1 | Cell projection, ruffle membrane | ||
| Mastermind-like protein 1 (Mam-1) | Nucleus speckle | ||
| Immunoglobulin-binding protein 1 (B-cell signal transduction molecule alpha 4) (Protein alpha-4) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit) (Renal carcinoma antigen NY-REN-16) | Cytoplasm | ||
| Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form] | Angiotensin-converting enzyme, soluble form: Secreted. | ||
| NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 2.3.2.26) (Atrophin-1-interacting protein 5) (AIP5) (HECT-type E3 ubiquitin transferase WWP1) (TGIF-interacting ubiquitin ligase 1) (Tiul1) (WW domain-containing protein 1) | Cytoplasm | ||
| Density-regulated protein (DRP) (Protein DRP1) (Smooth muscle cell-associated protein 3) (SMAP-3) | |||
| Obg-like ATPase 1 (DNA damage-regulated overexpressed in cancer 45) (DOC45) (GTP-binding protein 9) | Cytoplasm | ||
| Neuronal acetylcholine receptor subunit alpha-7 | Cell junction, synapse, postsynaptic cell membrane | ||
| Pro-FMRFamide-related neuropeptide VF [Cleaved into: Neuropeptide NPSF; Neuropeptide RFRP-1; Neuropeptide RFRP-2; Neuropeptide NPVF (Neuropeptide RFRP-3)] | Secreted. | ||
| Transcription initiation factor TFIID subunit 4 (RNA polymerase II TBP-associated factor subunit C) (TBP-associated factor 4) (Transcription initiation factor TFIID 130 kDa subunit) (TAF(II)130) (TAFII-130) (TAFII130) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) | Nucleus. | ||
| Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II) | Cytoplasm | ||
| Protein FAM168A (Tongue cancer chemotherapy resistance-associated protein 1) | |||
| PC4 and SFRS1-interacting protein (CLL-associated antigen KW-7) (Dense fine speckles 70 kDa protein) (DFS 70) (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) | Nucleus | ||
| Sorting nexin-24 | Cytoplasmic vesicle membrane | ||
| Protein FAM114A2 | |||
| Forkhead box protein D4-like 1 (FOXD4-like 1) | Nucleus | ||
| SAP30-binding protein (Transcriptional regulator protein HCNGP) | Nucleus | ||
| Leucyl-cystinyl aminopeptidase (Cystinyl aminopeptidase) (EC 3.4.11.3) (Insulin-regulated membrane aminopeptidase) (Insulin-responsive aminopeptidase) (IRAP) (Oxytocinase) (OTase) (Placental leucine aminopeptidase) (P-LAP) [Cleaved into: Leucyl-cystinyl aminopeptidase, pregnancy serum form] | Cell membrane | ||
| fMet-Leu-Phe receptor (fMLP receptor) (N-formyl peptide receptor) (FPR) (N-formylpeptide chemoattractant receptor) | Cell membrane | ||
| Fez family zinc finger protein 2 (Forebrain embryonic zinc finger-like protein 2) (Zinc finger protein 312) (Zinc finger protein Fez-like) | lateral sclerosis | Nucleus | |
| UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58) | |||
| Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF-like 2) (O/E-2) (OE-2) | autosomal dominant cerebellar ataxia | Nucleus | |
| Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1) | |||
| V-type proton ATPase 116 kDa subunit a isoform 3 (V-ATPase 116 kDa isoform a3) (Osteoclastic proton pump 116 kDa subunit) (OC-116 kDa) (OC116) (T-cell immune regulator 1) (T-cell immune response cDNA7 protein) (TIRC7) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3) | Membrane | ||
| Cyclin-K | Nucleus | ||
| Keratin-associated protein 12-4 (High sulfur keratin-associated protein 12.4) (Keratin-associated protein 12.4) | |||
| Tetratricopeptide repeat protein 9C (TPR repeat protein 9C) | |||
| Charged multivesicular body protein 4a (Chromatin-modifying protein 4a) (CHMP4a) (SNF7 homolog associated with Alix-2) (SNF7-1) (hSnf-1) (Vacuolar protein sorting-associated protein 32-1) (Vps32-1) (hVps32-1) | Cytoplasmic vesicle membrane | ||
| Golgin subfamily A member 5 (Cell proliferation-inducing gene 31 protein) (Golgin-84) (Protein Ret-II) (RET-fused gene 5 protein) | Golgi apparatus membrane | ||
| ATP-binding cassette sub-family B member 10, mitochondrial (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2) | Mitochondrion inner membrane | ||
| Olfactomedin-like protein 3 (HNOEL-iso) (hOLF44) | Secreted | ||
| DBH-like monooxygenase protein 1 (EC 1.14.17.-) (Monooxygenase X) | Endoplasmic reticulum membrane | ||
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2) (PDKII) | Mitochondrion matrix. | ||
| Protein ABHD14A (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 14A) (Abhydrolase domain-containing protein 14A) | Cytoplasm | ||
| Out at first protein homolog (HCV NS5A-transactivated protein 13 target protein 2) | |||
| Galanin peptides [Cleaved into: Galanin; Galanin message-associated peptide (GMAP)] | Secreted | ||
| Multidrug resistance-associated protein 7 (ATP-binding cassette sub-family C member 10) | Cell membrane | ||
| ATP-binding cassette sub-family A member 7 (ABCA-SSN) (Autoantigen SS-N) (Macrophage ABC transporter) | Alzheimer disease | Cell membrane | |
| Exocyst complex component 8 (Exocyst complex 84 kDa subunit) | Cytoplasm | ||
| Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1) | Isoform 1: Cell membrane | ||
| Calcitonin receptor (CT-R) | Cell membrane | ||
| Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead-related transcription factor 3) (FREAC-3) | Nucleus | ||
| POU domain, class 6, transcription factor 2 (Retina-derived POU domain factor 1) (RPF-1) | Nucleus | ||
| Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha) | Nucleus | ||
| Poly [ADP-ribose] polymerase 6 (PARP-6) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 17) (ARTD17) | |||
| General transcription factor IIH subunit 5 (General transcription factor IIH polypeptide 5) (TFB5 ortholog) (TFIIH basal transcription factor complex TTD-A subunit) | Nucleus | ||
| Mediator of RNA polymerase II transcription subunit 21 (Mediator complex subunit 21) (RNA polymerase II holoenzyme component SRB7) (RNAPII complex component SRB7) (hSrb7) | Nucleus | ||
| Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE) | Cytoplasm | ||
| Oxoeicosanoid receptor 1 (5-oxo-ETE G-protein coupled receptor) (G-protein coupled receptor 170) (G-protein coupled receptor R527) (G-protein coupled receptor TG1019) | Cell membrane | ||
| Cyclin-H (MO15-associated protein) (p34) (p37) | Nucleus. | ||
| Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MPF-2) (Short chain dehydrogenase/reductase family 8C member 1) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)] | Peroxisome. | ||
| UV-stimulated scaffold protein A | Chromosome | ||
| General transcription factor IIH subunit 3 (Basic transcription factor 2 34 kDa subunit) (BTF2 p34) (General transcription factor IIH polypeptide 3) (TFIIH basal transcription factor complex p34 subunit) | Nucleus | ||
| Hematopoietic prostaglandin D synthase (H-PGDS) (EC 5.3.99.2) (GST class-sigma) (Glutathione S-transferase) (EC 2.5.1.18) (Glutathione-dependent PGD synthase) (Glutathione-requiring prostaglandin D synthase) (Prostaglandin-H2 D-isomerase) | Cytoplasm | ||
| General transcription factor IIH subunit 1 (Basic transcription factor 2 62 kDa subunit) (BTF2 p62) (General transcription factor IIH polypeptide 1) (TFIIH basal transcription factor complex p62 subunit) | Nucleus. | ||
| Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1) | |||
| General transcription factor IIH subunit 4 (Basic transcription factor 2 52 kDa subunit) (BTF2 p52) (General transcription factor IIH polypeptide 4) (TFIIH basal transcription factor complex p52 subunit) | Nucleus. | ||
| Carcinoembryonic antigen-related cell adhesion molecule 6 (Non-specific crossreacting antigen) (Normal cross-reacting antigen) (CD antigen CD66c) | Cell membrane | ||
| Uncharacterized protein C6orf15 (Protein STG) | Secreted, extracellular space, extracellular matrix | ||
| HERV-H LTR-associating protein 3 (Human endogenous retrovirus-H long terminal repeat-associating protein 3) | |||
| Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65) | Cytoplasmic vesicle, secretory vesicle membrane | ||
| Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5) | |||
| Uncharacterized protein C6orf203 | |||
| 39S ribosomal protein L9, mitochondrial (L9mt) (MRP-L9) (Mitochondrial large ribosomal subunit protein bL9m) | Mitochondrion | ||
| 39S ribosomal protein L13, mitochondrial (L13mt) (MRP-L13) (Mitochondrial large ribosomal subunit protein uL13m) | Mitochondrion | ||
| 39S ribosomal protein L22, mitochondrial (L22mt) (MRP-L22) (39S ribosomal protein L25, mitochondrial) (L25mt) (MRP-L25) (Mitochondrial large ribosomal subunit protein uL22m) | Mitochondrion | ||
| 39S ribosomal protein L53, mitochondrial (L53mt) (MRP-L53) (Mitochondrial large ribosomal subunit protein mL53) | Mitochondrion | ||
| Dipeptidyl aminopeptidase-like protein 6 (DPPX) (Dipeptidyl aminopeptidase-related protein) (Dipeptidyl peptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl peptidase VI) (DPP VI) | Cell membrane | ||
| 5'-nucleotidase domain-containing protein 1 (EC 3.1.3.-) | |||
| Serine-threonine kinase receptor-associated protein (MAP activator with WD repeats) (UNR-interacting protein) (WD-40 repeat protein PT-WD) | |||
| 39S ribosomal protein L16, mitochondrial (L16mt) (MRP-L16) (Mitochondrial large ribosomal subunit protein uL16m) | Mitochondrion | ||
| Olfactory receptor 52W1 (Olfactory receptor OR11-71) | Cell membrane | ||
| Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1) | Endoplasmic reticulum membrane | ||
| Heme-binding protein 1 (p22HBP) | Cytoplasm | ||
| 2-hydroxyacyl-CoA lyase 1 (EC 4.1.-.-) (2-hydroxyphytanoyl-CoA lyase) (2-HPCL) (Phytanoyl-CoA 2-hydroxylase 2) | Peroxisome. | ||
| Sideroflexin-3 | Mitochondrion membrane | ||
| Protein Wnt-9b (Protein Wnt-14b) (Protein Wnt-15) | Secreted, extracellular space, extracellular matrix | ||
| DnaJ homolog subfamily C member 5 (Ceroid-lipofuscinosis neuronal protein 4) (Cysteine string protein) (CSP) | Membrane | ||
| RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1) | autosomal recessive cerebellar ataxia | Membrane, clathrin-coated pit | |
| SH3 domain-binding glutamic acid-rich-like protein 2 (Fovea-associated SH3 domain-binding protein) | Nucleus | ||
| Vacuolar protein sorting-associated protein 4A (EC 3.6.4.6) (Protein SKD2) (VPS4-1) (hVPS4) | Prevacuolar compartment membrane | ||
| cAMP-dependent protein kinase type II-alpha regulatory subunit | Cytoplasm | ||
| Testis anion transporter 1 (Anion exchange transporter) (Solute carrier family 26 member 8) | Membrane | ||
| Tektin-5 | Cell projection, cilium, flagellum | ||
| Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod) | Cytoplasm, cytoskeleton | ||
| Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor) | Sarcoplasmic reticulum membrane | ||
| Flotillin-2 (Epidermal surface antigen) (ESA) (Membrane component chromosome 17 surface marker 1) | Cell membrane | ||
| Synaptosomal-associated protein 23 (SNAP-23) (Vesicle-membrane fusion protein SNAP-23) | |||
| Galectin-4 (Gal-4) (Antigen NY-CO-27) (L-36 lactose-binding protein) (L36LBP) (Lactose-binding lectin 4) | |||
| Nuclear receptor subfamily 1 group D member 1 (Rev-erbA-alpha) (V-erbA-related protein 1) (EAR-1) | Nucleus | ||
| Septin-11 | Cytoplasm, cytoskeleton | ||
| Hematopoietic lineage cell-specific protein (Hematopoietic cell-specific LYN substrate 1) (LckBP1) (p75) | Membrane | ||
| Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform) | Nucleus matrix | ||
| Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding protein) (SR-BP) (Sigma 1-type opioid receptor) (SIG-1R) (Sigma1-receptor) (Sigma1R) (hSigmaR1) | lateral sclerosis amyotrophic lateral sclerosis | Nucleus inner membrane | |
| Proteasome subunit beta type-1 (EC 3.4.25.1) (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain) | Cytoplasm | ||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26) | Cytoplasm | ||
| Septin-9 (MLL septin-like fusion protein MSF-A) (MLL septin-like fusion protein) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1) | Cytoplasm, cytoskeleton | ||
| Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Canalicular multidrug resistance protein) (Multidrug resistance-associated protein 2) | Apical cell membrane | ||
| Sulfide:quinone oxidoreductase, mitochondrial (SQOR) (EC 1.8.5.-) (Sulfide dehydrogenase-like) (Sulfide quinone oxidoreductase) | Mitochondrion | ||
| Ras-related protein Rab-5A | Cell membrane | ||
| Ataxin-1-like (Brother of ataxin-1) (Brother of ATXN1) | Nucleus | ||
| Toll-interacting protein | Cytoplasm | ||
| Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1 (NC1)] | Secreted, extracellular space, extracellular matrix | ||
| Sorting nexin-14 | autosomal recessive cerebellar ataxia | Lysosome membrane | |
| Collagen alpha-1(I) chain (Alpha-1 type I collagen) | Secreted, extracellular space, extracellular matrix | ||
| Transcription initiation factor TFIID subunit 9 (RNA polymerase II TBP-associated factor subunit G) (STAF31/32) (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII31) (Transcription initiation factor TFIID 32 kDa subunit) (TAFII-32) (TAFII32) | Nucleus | ||
| Complement component C8 gamma chain | Secreted. | ||
| Nidogen-1 (NID-1) (Entactin) | Secreted, extracellular space, extracellular matrix, basement membrane. | ||
| Collagen alpha-1(VII) chain (Long-chain collagen) (LC collagen) | Secreted, extracellular space, extracellular matrix, basement membrane. | ||
| Keratin-associated protein 1-1 (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7) | |||
| Metabotropic glutamate receptor 1 (mGluR1) | autosomal dominant cerebellar ataxia autosomal recessive cerebellar ataxia | Cell membrane | |
| Cytochrome c oxidase assembly protein COX15 homolog | Mitochondrion membrane | ||
| Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Metalloprotease-related protein 1) (MPRP-1) (Overlapping with the m-AAA protease 1 homolog) | lateral sclerosis | Mitochondrion inner membrane | |
| Troponin T, fast skeletal muscle (TnTf) (Beta-TnTF) (Fast skeletal muscle troponin T) (fTnT) | |||
| Complex I intermediate-associated protein 30, mitochondrial (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1) | Parkinson disease | Mitochondrion | |
| Guanylin (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Guanylate cyclase-activating protein I) (GCAP-I) [Cleaved into: HMW-guanylin; Guanylin] | Secreted. | ||
| Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (Solute carrier family 25 member 11) | Mitochondrion inner membrane | ||
| Transmembrane protein 70, mitochondrial | Mitochondrion inner membrane | ||
| Retinol dehydrogenase 13 (EC 1.1.1.-) (Short chain dehydrogenase/reductase family 7C member 3) | |||
| Cytochrome c oxidase assembly protein COX11, mitochondrial | Mitochondrion inner membrane | ||
| Sideroflexin-4 (Breast cancer resistance marker 1) | Mitochondrion inner membrane | ||
| m7GpppN-mRNA hydrolase (EC 3.6.1.62) (Nucleoside diphosphate-linked moiety X motif 20) (Nudix motif 20) (mRNA-decapping enzyme 2) (hDpc) | Cytoplasm, P-body | ||
| Trans-Golgi network integral membrane protein 2 (TGN38 homolog) (TGN46) (TGN48) (Trans-Golgi network protein TGN51) | |||
| DNA polymerase epsilon subunit 2 (EC 2.7.7.7) (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B) | Nucleus. | ||
| Leucine-rich repeat-containing protein 46 | |||
| Kallikrein-11 (hK11) (EC 3.4.21.-) (Hippostasin) (Serine protease 20) (Trypsin-like protease) [Cleaved into: Kallikrein-11 inactive chain 1; Kallikrein-11 inactive chain 2] | Isoform 1: Secreted. | ||
| GPI-anchor transamidase (GPI transamidase) (EC 3.-.-.-) (GPI8 homolog) (hGPI8) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K) | Endoplasmic reticulum membrane | ||
| T-box transcription factor TBX15 (T-box protein 15) (T-box transcription factor TBX14) (T-box protein 14) | Nucleus | ||
| N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase) | Lysosome | ||
| UDP-glucose:glycoprotein glucosyltransferase 2 (UGT2) (hUGT2) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase 2) (UDP-glucose ceramide glucosyltransferase-like 1) | Endoplasmic reticulum lumen | ||
| Dr1-associated corepressor (Dr1-associated protein 1) (Negative cofactor 2-alpha) (NC2-alpha) | Nucleus | ||
| Leucine-rich repeats and immunoglobulin-like domains protein 2 (LIG-2) | Cell membrane | ||
| Epididymis-specific alpha-mannosidase (EC 3.2.1.24) (Mannosidase alpha class 2B member 2) | Secreted | ||
| Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 1) (Carma 1) | Cytoplasm | ||
| VIP peptides [Cleaved into: Intestinal peptide PHV-42 (Peptide histidine valine 42); Intestinal peptide PHM-27 (Peptide histidine methioninamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)] | Secreted. | ||
| Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase) | Endoplasmic reticulum lumen | ||
| Dickkopf-related protein 1 (Dickkopf-1) (Dkk-1) (hDkk-1) (SK) | Alzheimer disease | Secreted. | |
| Adenylyl cyclase-associated protein 1 (CAP 1) | Cell membrane | ||
| Transgelin (22 kDa actin-binding protein) (Protein WS3-10) (Smooth muscle protein 22-alpha) (SM22-alpha) | Cytoplasm | ||
| Thioredoxin domain-containing protein 17 (14 kDa thioredoxin-related protein) (TRP14) (Protein 42-9-9) (Thioredoxin-like protein 5) | Cytoplasm | ||
| LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1) | Cytoplasm | ||
| Growth arrest-specific protein 2 (GAS-2) | Cytoplasm, cytoskeleton, stress fiber | ||
| Phospholipase D1 (PLD 1) (hPLD1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) | Cytoplasm, perinuclear region | ||
| Destrin (Actin-depolymerizing factor) (ADF) | |||
| Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19) | Nucleus | ||
| Transmembrane and coiled-coil domain-containing protein 2 | Membrane | ||
| UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2) | Endoplasmic reticulum membrane | ||
| tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 (WD repeat-containing protein 4) | Nucleus | ||
| Docking protein 3 (Downstream of tyrosine kinase 3) | Cytoplasm | ||
| Cytokine receptor-like factor 2 (Cytokine receptor-like 2) (IL-XR) (Thymic stromal lymphopoietin protein receptor) (TSLP receptor) | Isoform 1: Cell membrane | ||
| Dipeptidyl peptidase 9 (DP9) (EC 3.4.14.5) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2) (Dipeptidyl peptidase IX) (DPP IX) (Dipeptidyl peptidase-like protein 9) (DPLP9) | Isoform 1: Cytoplasm, cytosol | ||
| Phospholipid phosphatase-related protein type 2 (EC 3.1.3.4) (Lipid phosphate phosphatase-related protein type 2) (Plasticity-related gene 4 protein) (PRG-4) | Membrane | ||
| Rho GTPase-activating protein 25 (Rho-type GTPase-activating protein 25) | |||
| Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2) | Cell membrane | ||
| Monoacylglycerol lipase ABHD12 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 12) | spastic ataxia | Membrane | |
| Beta-galactosidase-1-like protein 3 (EC 3.2.1.-) | |||
| Zinc finger protein SNAI1 (Protein snail homolog 1) (Protein sna) | Nucleus | ||
| Partitioning defective 6 homolog alpha (PAR-6) (PAR-6 alpha) (PAR-6A) (PAR6C) (Tax interaction protein 40) (TIP-40) | Cytoplasm | ||
| Tubulin alpha-3C chain (Alpha-tubulin 2) (Alpha-tubulin 3C) (Tubulin alpha-2 chain) [Cleaved into: Detyrosinated tubulin alpha-3C chain] | Cytoplasm, cytoskeleton. | ||
| PML-RARA-regulated adapter molecule 1 (PRAM) (PRAM-1) | |||
| Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor) | Endoplasmic reticulum membrane | ||
| CAP-Gly domain-containing linker protein 1 (Cytoplasmic linker protein 1) (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed-Sternberg intermediate filament-associated protein) (Restin) | Cytoplasm | ||
| Fc receptor-like protein 4 (FcR-like protein 4) (FcRL4) (Fc receptor homolog 4) (FcRH4) (IFGP family protein 2) (hIFGP2) (Immune receptor translocation-associated protein 1) (CD antigen CD307d) | Cell membrane | ||
| Cytospin-B (Nuclear structure protein 5) (NSP5) (Sperm antigen HCMOGT-1) (Sperm antigen with calponin homology and coiled-coil domains 1) | Nucleus | ||
| Apolipoprotein D (Apo-D) (ApoD) | Secreted. | ||
| Torsin-3A (ATP-dependent interferon-responsive protein) (Torsin family 3 member A) | Cytoplasm | ||
| Calmodulin-1 | Cytoplasm, cytoskeleton, spindle | ||
| Tigger transposable element-derived protein 5 | Nucleus | ||
| Immunoglobulin kappa variable 3D-7 | Secreted | ||
| Potassium voltage-gated channel subfamily E member 4 (MinK-related peptide 3) (Minimum potassium ion channel-related peptide 3) (Potassium channel subunit beta MiRP3) | Membrane | ||
| Refilin-A (Regulator of filamin protein A) (RefilinA) | Cytoplasm, cytoskeleton | ||
| Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) | |||
| General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (TF3C-delta) (Transcription factor IIIC 90 kDa subunit) (TFIIIC 90 kDa subunit) (TFIIIC90) (Transcription factor IIIC subunit delta) | Nucleus. | ||
| Protein LDOC1 (Leucine zipper protein down-regulated in cancer cells) | Nucleus | ||
| Forkhead box protein N4 | Nucleus | ||
| Olfactory receptor 2D3 (Olfactory receptor OR11-89) | Cell membrane | ||
| Transcription factor jun-D | Nucleus. | ||
| CREB-regulated transcription coactivator 2 (Transducer of regulated cAMP response element-binding protein 2) (TORC-2) (Transducer of CREB protein 2) | Cytoplasm | ||
| Inhibin beta B chain (Activin beta-B chain) | Secreted. | ||
| ETS translocation variant 4 (Adenovirus E1A enhancer-binding protein) (E1A-F) (Polyomavirus enhancer activator 3 homolog) (Protein PEA3) | Nucleus. | ||
| Meiotic recombination protein DMC1/LIM15 homolog | Nucleus | ||
| T-complex protein 11-like protein 2 | |||
| Glycerol kinase 3 (GK 3) (Glycerokinase 3) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 3) (Glycerol kinase 3 pseudogene) (Glycerol kinase, testis specific 1) | Mitochondrion outer membrane | ||
| Collagen alpha-1(X) chain | Secreted, extracellular space, extracellular matrix | ||
| Proteasome assembly chaperone 2 (PAC-2) (Hepatocellular carcinoma-susceptibility protein 3) (Tumor necrosis factor superfamily member 5-induced protein 1) | Nucleus | ||
| Zinc finger MYND domain-containing protein 12 | |||
| Gamma-aminobutyric acid receptor subunit rho-2 (GABA(A) receptor subunit rho-2) (GABA(C) receptor) | Cell junction, synapse, postsynaptic cell membrane | ||
| Ras-like protein family member 12 (Ras-like protein Ris) | |||
| Alpha-1-antichymotrypsin (ACT) (Cell growth-inhibiting gene 24/25 protein) (Serpin A3) [Cleaved into: Alpha-1-antichymotrypsin His-Pro-less] | Secreted. | ||
| Zinc finger and BTB domain-containing protein 42 | Cytoplasm | ||
| Cystatin-M (Cystatin-6) (Cystatin-E) | Secreted. | ||
| Neurofilament heavy polypeptide (NF-H) (200 kDa neurofilament protein) (Neurofilament triplet H protein) | lateral sclerosis amyotrophic lateral sclerosis | Cytoplasm | |
| Gastrokine-2 (Blottin) (Down-regulated in gastric cancer) (Trefoil factor interactions(z) 1) | Secreted. | ||
| Keratin-associated protein 12-1 (High sulfur keratin-associated protein 12.1) (Keratin-associated protein 12.1) | |||
| Nuclear protein 1 (Candidate of metastasis 1) (Nuclear transcriptional regulator protein 1) (Protein p8) | Nucleus | ||
| Zinc finger protein 76 (Zinc finger protein 523) | Nucleus | ||
| Aryl hydrocarbon receptor (Ah receptor) (AhR) (Class E basic helix-loop-helix protein 76) (bHLHe76) | Cytoplasm | ||
| Alkaline ceramidase 1 (AlkCDase 1) (Alkaline CDase 1) (EC 3.5.1.23) (Acylsphingosine deacylase 3) (N-acylsphingosine amidohydrolase 3) | Endoplasmic reticulum membrane | ||
| Vacuolar protein sorting-associated protein 18 homolog (hVPS18) | Late endosome membrane | ||
| Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (PITPnm 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3) | Endomembrane system | ||
| Apolipoprotein L3 (Apolipoprotein L-III) (ApoL-III) (TNF-inducible protein CG12-1) (CG12_1) | Cytoplasm | ||
| GA-binding protein alpha chain (GABP subunit alpha) (Nuclear respiratory factor 2 subunit alpha) (Transcription factor E4TF1-60) | Nucleus. | ||
| Interferon regulatory factor 7 (IRF-7) | |||
| Pregnancy-specific beta-1-glycoprotein 3 (PS-beta-G-3) (PSBG-3) (Pregnancy-specific glycoprotein 3) (Carcinoembryonic antigen SG5) | Secreted | ||
| Transcription factor Sp6 (Krueppel-like factor 14) | Nucleus | ||
| Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP) | Nucleus. | ||
| Activated RNA polymerase II transcriptional coactivator p15 (Positive cofactor 4) (PC4) (SUB1 homolog) (p14) | Nucleus. | ||
| Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha) (Nuclear receptor subfamily 1 group F member 1) (RAR-related orphan receptor A) (Retinoid-related orphan receptor-alpha) | autosomal dominant cerebellar ataxia autism spectrum disorder | Nucleus | |
| Psoriasis susceptibility 1 candidate gene 2 protein (Protein SPR1) | Secreted | ||
| Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Basic-helix-loop-helix-PAS protein MOP3) (Brain and muscle ARNT-like 1) (Class E basic helix-loop-helix protein 5) (bHLHe5) (Member of PAS protein 3) (PAS domain-containing protein 3) (bHLH-PAS protein JAP3) | Nucleus | ||
| Choline kinase alpha (CK) (EC 2.7.1.32) (CHETK-alpha) (Ethanolamine kinase) (EK) (EC 2.7.1.82) | Cytoplasm. | ||
| Autism susceptibility gene 2 protein | autism spectrum disorder | Nucleus | |
| Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1) | Cytoplasm | ||
| TATA box-binding protein-associated factor RNA polymerase I subunit B (RNA polymerase I-specific TBP-associated factor 63 kDa) (TAFI63) (TATA box-binding protein-associated factor 1B) (TBP-associated factor 1B) (Transcription initiation factor SL1/TIF-IB subunit B) | Nucleus, nucleolus. | ||
| Signal transducer and activator of transcription 5A | Cytoplasm | ||
| Neuritin-like protein | Cell membrane | ||
| Sex-determining region Y protein (Testis-determining factor) | Nucleus speckle | ||
| Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear receptor subfamily 1 group H member 3) | Nucleus | ||
| General transcription factor 3C polypeptide 2 (TF3C-beta) (Transcription factor IIIC 110 kDa subunit) (TFIIIC 110 kDa subunit) (TFIIIC110) (Transcription factor IIIC subunit beta) | Nucleus. | ||
| Toll-like receptor 10 (CD antigen CD290) | Membrane | ||
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase) | Nucleus. | ||
| Mineralocorticoid receptor (MR) (Nuclear receptor subfamily 3 group C member 2) | |||
| Nuclear transcription factor Y subunit alpha (CAAT box DNA-binding protein subunit A) (Nuclear transcription factor Y subunit A) (NF-YA) | Nucleus. | ||
| Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-gamma) (PP2A B subunit isoform PR61-gamma) (PP2A B subunit isoform R5-gamma) (Renal carcinoma antigen NY-REN-29) | Nucleus | ||
| Potassium voltage-gated channel subfamily C member 3 (KSHIIID) (Voltage-gated potassium channel subunit Kv3.3) | autosomal dominant cerebellar ataxia | Cell membrane | |
| Neuropeptide Y receptor type 5 (NPY5-R) (NPY-Y5 receptor) (NPYY5-R) (Y5 receptor) | Cell membrane | ||
| E3 SUMO-protein ligase PIAS3 (EC 2.3.2.-) (E3 SUMO-protein transferase PIAS3) (Protein inhibitor of activated STAT protein 3) | Cytoplasm | ||
| Ras-related protein Rab-42 | Membrane | ||
| Mastermind-like protein 2 (Mam-2) | Nucleus speckle | ||
| Probable G-protein coupled receptor 162 (Gene-rich cluster gene A protein) | Cell membrane | ||
| TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Fetal liver LKB1-interacting protein) | Cytoplasm | ||
| 26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin) (p28(GANK)) | Cytoplasm | ||
| EP300-interacting inhibitor of differentiation 2 (EID-2) (CREBBP/EP300 inhibitor 2) (EID-1-like inhibitor of differentiation 2) | Nucleus | ||
| Transcription initiation factor IIB (EC 2.3.1.48) (General transcription factor TFIIB) (S300-II) | Nucleus | ||
| Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial | Mitochondrion | ||
| Transcriptional adapter 3 (ADA3 homolog) (hADA3) (STAF54) (Transcriptional adapter 3-like) (ADA3-like protein) | Nucleus | ||
| Myocyte-specific enhancer factor 2C (Myocyte enhancer factor 2C) | Nucleus | ||
| Endothelin-2 (ET-2) (Preproendothelin-2) (PPET2) | Secreted. | ||
| Junction-mediating and -regulatory protein | Nucleus | ||
| Achaete-scute homolog 1 (ASH-1) (hASH1) (Class A basic helix-loop-helix protein 46) (bHLHa46) | Nucleus | ||
| Peptide chain release factor 1, mitochondrial (MRF-1) (MtRF-1) | Mitochondrion | ||
| Lysine-specific demethylase 3A (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2A) (Jumonji domain-containing protein 1A) | Cytoplasm | ||
| Nuclear factor of activated T-cells, cytoplasmic 2 (NF-ATc2) (NFATc2) (NFAT pre-existing subunit) (NF-ATp) (T-cell transcription factor NFAT1) | |||
| Ovochymase-1 (EC 3.4.21.-) | Secreted | ||
| Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein) | autism spectrum disorder | Nucleus | |
| Interferon alpha/beta receptor 1 (IFN-R-1) (IFN-alpha/beta receptor 1) (Cytokine receptor class-II member 1) (Cytokine receptor family 2 member 1) (CRF2-1) (Type I interferon receptor 1) | Isoform 1: Cell membrane | ||
| Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) | |||
| Mitochondrial import inner membrane translocase subunit Tim9 | Mitochondrion inner membrane | ||
| Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Protein MSL3-1) (Transcription factor-like protein MRG15) | Nucleus. | ||
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB) | Nucleus | ||
| Interferon regulatory factor 1 (IRF-1) | |||
| Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TR-interacting protein 4) (TRIP-4) | Nucleus | ||
| Sodium channel protein type 10 subunit alpha (Peripheral nerve sodium channel 3) (PN3) (hPN3) (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) | Cell membrane | ||
| Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)] | |||
| Sodium channel protein type 11 subunit alpha (Peripheral nerve sodium channel 5) (PN5) (Sensory neuron sodium channel 2) (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (hNaN) | Cell membrane | ||
| Runt-related transcription factor 2 (Acute myeloid leukemia 3 protein) (Core-binding factor subunit alpha-1) (CBF-alpha-1) (Oncogene AML-3) (Osteoblast-specific transcription factor 2) (OSF-2) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEA2-alpha A) (PEBP2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) | Nucleus | ||
| Izumo sperm-egg fusion protein 4 (Sperm 22 kDa protein c113) | Secreted | ||
| 40S ribosomal protein S26 (Small ribosomal subunit protein eS26) | Cytoplasm, cytosol | ||
| Protein phosphatase 1 regulatory subunit 3D (Protein phosphatase 1 regulatory subunit 6) (PP1 subunit R6) (Protein phosphatase 1-binding subunit R6) | |||
| E3 ubiquitin-protein ligase NHLRC1 (EC 2.3.2.27) (Malin) (NHL repeat-containing protein 1) (RING-type E3 ubiquitin transferase NHLRC1) | Lafora disease | ||
| Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) | Mitochondrion outer membrane | ||
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) | Cytoplasm | ||
| NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (HIRA-interacting protein 5) | Mitochondrion | ||
| Protein phosphatase 1 regulatory subunit 3C (Protein phosphatase 1 regulatory subunit 5) (PP1 subunit R5) (Protein targeting to glycogen) (PTG) | |||
| E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (Putative transcription factor XPRF) (RING finger protein 59) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18) | Cytoplasm | ||
| Cysteine and histidine-rich protein 1 | Cytoplasm | ||
| [Protein ADP-ribosylarginine] hydrolase-like protein 1 (EC 3.2.-.-) (ADP-ribosylhydrolase 2) | |||
| Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter) | autosomal recessive cerebellar ataxia | Cell membrane | |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (Cell death regulatory protein GRIM-19) (Complex I-B16.6) (CI-B16.6) (Gene associated with retinoic and interferon-induced mortality 19 protein) (GRIM-19) (Gene associated with retinoic and IFN-induced mortality 19 protein) (NADH-ubiquinone oxidoreductase B16.6 subunit) | Mitochondrion inner membrane | ||
| UPF0686 protein C11orf1 | Nucleus | ||
| Ephrin-A5 (AL-1) (EPH-related receptor tyrosine kinase ligand 7) (LERK-7) | Cell membrane | ||
| U6 snRNA-associated Sm-like protein LSm7 | Nucleus | ||
| Insulin, isoform 2 (INS-IGF2 readthrough transcript protein) | |||
| Complement C1q tumor necrosis factor-related protein 4 (C1q/TNF-related protein 4) | Secreted | ||
| VPS10 domain-containing receptor SorCS3 | Membrane | ||
| Immunoglobulin superfamily DCC subclass member 3 (Putative neuronal cell adhesion molecule) | Membrane | ||
| RecQ-mediated genome instability protein 1 (BLM-associated protein of 75 kDa) (BLAP75) (FAAP75) | Nucleus | ||
| DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha) | autosomal recessive cerebellar ataxia | Mitochondrion matrix | |
| Ubiquitin-like protein 7 (Bone marrow stromal cell ubiquitin-like protein) (BMSC-UbP) (Ubiquitin-like protein SB132) | |||
| RAB6A-GEF complex partner protein 2 (Retrograde Golgi transport protein RGP1 homolog) | Cytoplasm, cytosol | ||
| Glutathione S-transferase theta-2B (EC 2.5.1.18) (GST class-theta-2) (Glutathione S-transferase theta-2) | Cytoplasm. | ||
| E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING finger protein 147) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147) | Cytoplasm | ||
| General transcription factor IIF subunit 1 (General transcription factor IIF 74 kDa subunit) (Transcription initiation factor IIF subunit alpha) (TFIIF-alpha) (Transcription initiation factor RAP74) | Nucleus. | ||
| Metabotropic glutamate receptor 8 (mGluR8) | Cell membrane | ||
| N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (AP lyase) (EC 4.2.99.18)] | Nucleus, nucleoplasm | ||
| Tyrosine-protein kinase BAZ1B (EC 2.7.10.2) (Bromodomain adjacent to zinc finger domain protein 1B) (Williams syndrome transcription factor) (Williams-Beuren syndrome chromosomal region 10 protein) (Williams-Beuren syndrome chromosomal region 9 protein) (hWALp2) | Nucleus | ||
| Small glutamine-rich tetratricopeptide repeat-containing protein beta (Beta-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 2) | |||
| Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) | Cytoplasm | ||
| Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18) (Microsomal GST-II) | Endoplasmic reticulum membrane | ||
| Organic solute transporter subunit beta (OST-beta) (Solute carrier family 51 subunit beta) | Cell membrane | ||
| M-phase phosphoprotein 6 | |||
| Cell division control protein 42 homolog (G25K GTP-binding protein) | Cell membrane | ||
| 39S ribosomal protein L38, mitochondrial (L38mt) (MRP-L38) (Mitochondrial large ribosomal subunit protein mL38) | Mitochondrion | ||
| Glutamate receptor ionotropic, kainate 3 (GluK3) (Excitatory amino acid receptor 5) (EAA5) (Glutamate receptor 7) (GluR-7) (GluR7) | Cell membrane | ||
| P2Y purinoceptor 2 (P2Y2) (ATP receptor) (P2U purinoceptor 1) (P2U1) (P2U receptor 1) (Purinergic receptor) | Cell membrane | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 (NADH-ubiquinone oxidoreductase MLRQ subunit homolog) (NUOMS) | |||
| DNA-directed RNA polymerase III subunit RPC6 (RNA polymerase III subunit C6) (DNA-directed RNA polymerase III subunit F) (RNA polymerase III 39 kDa subunit) (RPC39) | Nucleus | ||
| Low affinity immunoglobulin gamma Fc region receptor II-b (IgG Fc receptor II-b) (CDw32) (Fc-gamma RII-b) (Fc-gamma-RIIb) (FcRII-b) (CD antigen CD32) | Cell membrane | ||
| Sodium/potassium-transporting ATPase subunit alpha-3 (Na(+)/K(+) ATPase alpha-3 subunit) (EC 3.6.3.9) (Na(+)/K(+) ATPase alpha(III) subunit) (Sodium pump subunit alpha-3) | autosomal dominant cerebellar ataxia | Cell membrane | |
| T-box transcription factor T (Brachyury protein) (Protein T) | Nucleus | ||
| D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH) (Short chain dehydrogenase/reductase family 9C member 1) | Mitochondrion inner membrane | ||
| StAR-related lipid transfer protein 3 (Metastatic lymph node gene 64 protein) (MLN 64) (Protein CAB1) (START domain-containing protein 3) (StARD3) | Late endosome membrane | ||
| Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER-Golgi intermediate compartment 32 kDa protein) (ERGIC-32) | Endoplasmic reticulum membrane | ||
| Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein) | progressive muscular atrophy | Endoplasmic reticulum membrane | |
| Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U) | Endoplasmic reticulum membrane | ||
| Butyrophilin subfamily 3 member A2 | Cell membrane | ||
| Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Voltage-gated calcium channel subunit alpha Cav1.3) | autism spectrum disorder | Membrane | |
| COUP transcription factor 2 (COUP-TF2) (Apolipoprotein A-I regulatory protein 1) (ARP-1) (COUP transcription factor II) (COUP-TF II) (Nuclear receptor subfamily 2 group F member 2) | Nucleus. | ||
| Pseudouridine-5'-phosphatase (EC 3.1.3.96) (Haloacid dehalogenase-like hydrolase domain-containing protein 1) (Haloacid dehalogenase-like hydrolase domain-containing protein 1A) (Protein GS1) (Pseudouridine-5'-monophosphatase) (5'-PsiMPase) | |||
| Transmembrane protein 186 | Membrane | ||
| Sulfate transporter (Diastrophic dysplasia protein) (Solute carrier family 26 member 2) | Cell membrane | ||
| Dolichol kinase (EC 2.7.1.108) (Transmembrane protein 15) | Endoplasmic reticulum membrane | ||
| Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1) | Cytoplasm, cytoskeleton | ||
| Receptor activity-modifying protein 3 (Calcitonin-receptor-like receptor activity-modifying protein 3) (CRLR activity-modifying protein 3) | Cell membrane | ||
| Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] | Endoplasmic reticulum membrane | ||
| Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3) | Cytoplasm | ||
| Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1) | autosomal recessive cerebellar ataxia | Cell membrane | |
| Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4) | Endoplasmic reticulum lumen | ||
| TP53-regulated inhibitor of apoptosis 1 (Protein 15E1.1) (WF-1) (p53-inducible cell-survival factor) (p53CSV) | Cytoplasm, perinuclear region | ||
| Intraflagellar transport protein 43 homolog | Cytoplasm, cytoskeleton | ||
| Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T-cell transcription factor NFAT3) (NF-AT3) | Cytoplasm | ||
| Uncharacterized protein C11orf74 (Protein HEPIS) | |||
| Synaptotagmin-9 (Synaptotagmin IX) (SytIX) | lateral sclerosis | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane | |
| Cystathionine beta-synthase (EC 4.2.1.22) (Beta-thionase) (Serine sulfhydrase) | Cytoplasm | ||
| Cystathionine beta-synthase-like protein (EC 4.2.1.22) (Beta-thionase) (Serine sulfhydrase) | Cytoplasm | ||
| Glycoprotein endo-alpha-1,2-mannosidase-like protein (EC 3.2.1.-) | Golgi apparatus membrane | ||
| Gem-associated protein 6 (Gemin-6) (SIP2) | Nucleus, nucleoplasm | ||
| Annexin A3 (35-alpha calcimedin) (Annexin III) (Annexin-3) (Inositol 1,2-cyclic phosphate 2-phosphohydrolase) (Lipocortin III) (Placental anticoagulant protein III) (PAP-III) | |||
| Caldesmon (CDM) | Cytoplasm, cytoskeleton | ||
| Protein angel homolog 1 | |||
| U7 snRNA-associated Sm-like protein LSm11 | Nucleus | ||
| Contactin-associated protein-like 3B (Cell recognition molecule Caspr3b) | Membrane | ||
| Nuclear receptor subfamily 0 group B member 1 (DSS-AHC critical region on the X chromosome protein 1) (Nuclear receptor DAX-1) | Nucleus | ||
| Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (Androgen receptor coactivator 267 kDa protein) (Androgen receptor-associated protein of 267 kDa) (H3-K36-HMTase) (H4-K20-HMTase) (Lysine N-methyltransferase 3B) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) | Nucleus | ||
| Proline-rich nuclear receptor coactivator 2 | Nucleus | ||
| Nuclear receptor subfamily 0 group B member 2 (Orphan nuclear receptor SHP) (Small heterodimer partner) | Nucleus | ||
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4) | Mitochondrion matrix. | ||
| Integrin alpha-11 | Membrane | ||
| Steroid hormone receptor ERR2 (ERR beta-2) (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2) | Nucleus | ||
| 40S ribosomal protein S27-like (Small ribosomal subunit protein eS27-like) | |||
| DnaJ homolog subfamily B member 2 (Heat shock 40 kDa protein 3) (Heat shock protein J1) (HSJ-1) | progressive muscular atrophy | Isoform 2: Cytoplasm | |
| Dynein regulatory complex subunit 4 (Growth arrest-specific protein 11) (GAS-11) (Growth arrest-specific protein 8) (GAS-8) | Cytoplasm | ||
| DnaJ homolog subfamily B member 8 | |||
| Pre-B-cell leukemia transcription factor 4 (Homeobox protein PBX4) | Nucleus | ||
| Microsomal glutathione S-transferase 1 (Microsomal GST-1) (EC 2.5.1.18) (Microsomal GST-I) | Microsome | ||
| ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (MIG-6) | Cytoplasm | ||
| Protein S100-A16 (Aging-associated gene 13 protein) (Protein S100-F) (S100 calcium-binding protein A16) | Nucleus, nucleolus | ||
| Proline-rich nuclear receptor coactivator 1 (Proline-rich protein 2) (Protein B4-2) | Nucleus | ||
| Guanylate cyclase activator 2B [Cleaved into: Guanylate cyclase C-activating peptide 2 (Guanylate cyclase C-activating peptide II) (GCAP-II); Uroguanylin (UGN)] | Secreted. | ||
| Tubby-related protein 3 (Tubby-like protein 3) | Nucleus | ||
| Ubiquitin-60S ribosomal protein L40 (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; 60S ribosomal protein L40 (Large ribosomal subunit protein eL40)] | Ubiquitin: Cytoplasm | ||
| SHC-transforming protein 2 (Protein Sck) (SHC-transforming protein B) (Src homology 2 domain-containing-transforming protein C2) (SH2 domain protein C2) | |||
| Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene) | Cell membrane | ||
| Actin, alpha cardiac muscle 1 (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form] | Cytoplasm, cytoskeleton. | ||
| Methanethiol oxidase (MTO) (EC 1.8.3.4) (56 kDa selenium-binding protein) (SBP56) (SP56) (Selenium-binding protein 1) | Nucleus | ||
| Cathelicidin antimicrobial peptide (18 kDa cationic antimicrobial protein) (CAP-18) (hCAP-18) [Cleaved into: Antibacterial peptide FALL-39 (FALL-39 peptide antibiotic); Antibacterial peptide LL-37] | Secreted. | ||
| ADP-ribosylation factor-like protein 3 | autosomal recessive cerebellar ataxia | ||
| Integral membrane protein 2A (Protein E25) | Membrane | ||
| Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase B) (IP3 3-kinase B) (IP3K B) (InsP 3-kinase B) | |||
| Heparan-sulfate 6-O-sulfotransferase 1 (HS6ST-1) (EC 2.8.2.-) | Membrane | ||
| ATPase ASNA1 (EC 3.6.-.-) (Arsenical pump-driving ATPase) (Arsenite-stimulated ATPase) (Transmembrane domain recognition complex 40 kDa ATPase subunit) (hARSA-I) (hASNA-I) | Cytoplasm | ||
| Beta-1,4 N-acetylgalactosaminyltransferase 1 (EC 2.4.1.92) ((N-acetylneuraminyl)-galactosylglucosylceramide) (GM2/GD2 synthase) (GalNAc-T) | Golgi apparatus membrane | ||
| Endothelial cell-specific molecule 1 (ESM-1) | Secreted. | ||
| Ski oncogene (Proto-oncogene c-Ski) | Nucleus. | ||
| Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10 protein) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2) (Oncogene Lyt-10) (Lyt10) [Cleaved into: Nuclear factor NF-kappa-B p52 subunit] | |||
| Heterogeneous nuclear ribonucleoprotein A1-like 2 (hnRNP A1-like 2) (hnRNP core protein A1-like 2) | Nucleus | ||
| Thyroid hormone receptor-associated protein 3 (BCLAF1 and THRAP3 family member 2) (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150) | Nucleus | ||
| E3 ubiquitin-protein ligase RNF4 (EC 2.3.2.27) (RING finger protein 4) (RING-type E3 ubiquitin transferase RNF4) (Small nuclear ring finger protein) (Protein SNURF) | Cytoplasm | ||
| Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Type-II keratin Kb4) | |||
| POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) (Octamer-binding protein 2) (Oct-2) (Octamer-binding transcription factor 2) (OTF-2) | Cytoplasm | ||
| Transcription initiation factor TFIID subunit 2 (150 kDa cofactor of initiator function) (RNA polymerase II TBP-associated factor subunit B) (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150) | Nucleus | ||
| Mediator of RNA polymerase II transcription subunit 25 (Activator interaction domain-containing protein 1) (Activator-recruited cofactor 92 kDa component) (ARC92) (Mediator complex subunit 25) (p78) | Nucleus | ||
| Uncharacterized protein encoded by LINC01600 | |||
| Keratin-associated protein 6-2 | |||
| Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) | |||
| Putative protein CLUHP3 (Clustered mitochondria (cluA/CLU1) homolog pseudogene 3) (KIAA0664-like protein 3) | |||
| Protein MRVI1 (Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate) (JAW1-related protein MRVI1) | Cytoplasm, perinuclear region | ||
| Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5) | Cytoplasm | ||
| Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor) | Nucleus speckle | ||
| Acidic leucine-rich nuclear phosphoprotein 32 family member A (Acidic nuclear phosphoprotein pp32) (pp32) (Leucine-rich acidic nuclear protein) (LANP) (Mapmodulin) (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Putative HLA-DR-associated protein I) (PHAPI) | |||
| Hepatocyte nuclear factor 3-alpha (HNF-3-alpha) (HNF-3A) (Forkhead box protein A1) (Transcription factor 3A) (TCF-3A) | Nucleus | ||
| Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) (Cerebral protein 6) | Cytoplasm | ||
| AT-rich interactive domain-containing protein 5A (ARID domain-containing protein 5A) (Modulator recognition factor 1) (MRF-1) | Nucleus | ||
| Protein NDRG2 (N-myc downstream-regulated gene 2 protein) (Protein Syld709613) | Alzheimer disease | Cytoplasm | |
| E3 ubiquitin-protein ligase RLIM (EC 2.3.2.27) (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (RING finger protein 12) (RING-type E3 ubiquitin transferase RLIM) (Renal carcinoma antigen NY-REN-43) | Nucleus | ||
| Dynein assembly factor 4, axonemal (Dyslexia susceptibility 1 candidate gene 1 protein) | Nucleus | ||
| RNA-binding protein Musashi homolog 1 (Musashi-1) | Cytoplasm | ||
| SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat-containing protein) | |||
| Tumor necrosis factor ligand superfamily member 15 (TNF ligand-related molecule 1) (Vascular endothelial cell growth inhibitor) [Cleaved into: Tumor necrosis factor ligand superfamily member 15, membrane form; Tumor necrosis factor ligand superfamily member 15, secreted form] | Membrane | ||
| Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1) | Nucleus | ||
| Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) | Lysosome | ||
| POU domain, class 2, transcription factor 1 (NF-A1) (Octamer-binding protein 1) (Oct-1) (Octamer-binding transcription factor 1) (OTF-1) | Nucleus. | ||
| Forkhead box protein O4 (Fork head domain transcription factor AFX1) | |||
| RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 2.3.2.31) (HBV-associated factor 4) (Heme-oxidized IRP2 ubiquitin ligase 1) (HOIL-1) (Hepatitis B virus X-associated protein 4) (RING finger protein 54) (RING-type E3 ubiquitin transferase HOIL-1) (Ubiquitin-conjugating enzyme 7-interacting protein 3) | |||
| Guanine nucleotide exchange factor VAV3 (VAV-3) | |||
| Keratin, type I cytoskeletal 26 (Cytokeratin-26) (CK-26) (Keratin-25B) (K25B) (Keratin-26) (K26) (Type I inner root sheath-specific keratin-K25irs2) | |||
| Keratin, type I cytoskeletal 27 (Cytokeratin-27) (CK-27) (Keratin-25C) (K25C) (Keratin-27) (K27) (Type I inner root sheath-specific keratin-K25irs3) | Cytoplasm | ||
| Opioid-binding protein/cell adhesion molecule (OBCAM) (OPCML) (Opioid-binding cell adhesion molecule) (IgLON family member 1) | Cell membrane | ||
| Keratin-associated protein 13-2 | |||
| TATA box-binding protein-associated factor RNA polymerase I subunit A (RNA polymerase I-specific TBP-associated factor 48 kDa) (TAFI48) (TATA box-binding protein-associated factor 1A) (TBP-associated factor 1A) (Transcription factor SL1) (Transcription initiation factor SL1/TIF-IB subunit A) | Nucleus. | ||
| Aryl hydrocarbon receptor repressor (AhR repressor) (AhRR) (Class E basic helix-loop-helix protein 77) (bHLHe77) | Cytoplasm | ||
| Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b) | Nucleus | ||
| Histone deacetylase 7 (HD7) (EC 3.5.1.98) (Histone deacetylase 7A) (HD7a) | |||
| Ubiquitin conjugation factor E4 B (EC 2.3.2.27) (Homozygously deleted in neuroblastoma 1) (RING-type E3 ubiquitin transferase E4 B) (Ubiquitin fusion degradation protein 2) | Cytoplasm | ||
| Transmembrane protein 106C (Endoplasmic reticulum membrane protein overexpressed in cancer) | Endoplasmic reticulum membrane | ||
| Patched domain-containing protein 1 | autism spectrum disorder | Cell membrane | |
| Thioredoxin reductase 1, cytoplasmic (TR) (EC 1.8.1.9) (Gene associated with retinoic and interferon-induced mortality 12 protein) (GRIM-12) (Gene associated with retinoic and IFN-induced mortality 12 protein) (KM-102-derived reductase-like factor) (Thioredoxin reductase TR1) | Cytoplasm | ||
| Histone-lysine N-methyltransferase KMT5B (EC 2.1.1.43) (Lysine N-methyltransferase 5B) (Lysine-specific methyltransferase 5B) (Suppressor of variegation 4-20 homolog 1) (Su(var)4-20 homolog 1) (Suv4-20h1) | autism spectrum disorder | Nucleus | |
| Brorin (Brain-specific chordin-like protein) (von Willebrand factor C domain-containing protein 2) | Secreted, extracellular space, extracellular matrix, basement membrane | ||
| TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 3) (NF-kappa-B-activating protein 1) (TAK1-binding protein 3) (TAB-3) (TGF-beta-activated kinase 1-binding protein 3) | |||
| Keratin-associated protein 19-6 | |||
| Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1) | Cytoplasm | ||
| Nucleolar protein 58 (Nucleolar protein 5) | Nucleus, nucleolus | ||
| Claudin-4 (Clostridium perfringens enterotoxin receptor) (CPE-R) (CPE-receptor) (Williams-Beuren syndrome chromosomal region 8 protein) | Cell junction, tight junction | ||
| Zinc finger and SCAN domain-containing protein 23 (Zinc finger protein 390) (Zinc finger protein 453) | Nucleus | ||
| Kremen protein 1 (Dickkopf receptor) (Kringle domain-containing transmembrane protein 1) (Kringle-containing protein marking the eye and the nose) | Cell membrane | ||
| Natriuretic peptides A (CDD-ANF) (Cardiodilatin) (CDD) (Cardiodilatin-related peptide) (CDP) (Prepronatriodilatin) [Cleaved into: Atrial natriuretic factor (ANF) (Atrial natriuretic peptide) (ANP)] | Secreted. | ||
| Coronin-1C (Coronin-3) (hCRNN4) | Cell membrane | ||
| Nuclear receptor coactivator 4 (NCoA-4) (Androgen receptor coactivator 70 kDa protein) (70 kDa AR-activator) (70 kDa androgen receptor coactivator) (Androgen receptor-associated protein of 70 kDa) (Ret-activating protein ELE1) | |||
| 2,4-dienoyl-CoA reductase, mitochondrial (EC 1.3.1.34) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) (Short chain dehydrogenase/reductase family 18C member 1) | Mitochondrion. | ||
| Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3) | Nucleus. | ||
| WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP) | Nucleus, nucleolus | ||
| Homologous-pairing protein 2 homolog (Nuclear receptor coactivator GT198) (PSMC3-interacting protein) (Proteasome 26S ATPase subunit 3-interacting protein) (Tat-binding protein 1-interacting protein) (TBP-1-interacting protein) | Nucleus | ||
| Zinc finger and SCAN domain-containing protein 30 (ZNF-WYM) (Zinc finger protein 397 opposite strand) (Zinc finger protein 397OS) | Nucleus | ||
| Bladder cancer-associated protein (Bladder cancer 10 kDa protein) (Bc10) | Membrane | ||
| Vigilin (High density lipoprotein-binding protein) (HDL-binding protein) | Cytoplasm | ||
| POZ-, AT hook-, and zinc finger-containing protein 1 (BTB/POZ domain zinc finger transcription factor) (Protein kinase A RI subunit alpha-associated protein) (Zinc finger and BTB domain-containing protein 19) (Zinc finger protein 278) (Zinc finger sarcoma gene protein) | Nucleus | ||
| Proteasome subunit beta type-9 (EC 3.4.25.1) (Low molecular mass protein 2) (Macropain chain 7) (Multicatalytic endopeptidase complex chain 7) (Proteasome chain 7) (Proteasome subunit beta-1i) (Really interesting new gene 12 protein) | Cytoplasm | ||
| Sorting nexin-6 (TRAF4-associated factor 2) [Cleaved into: Sorting nexin-6, N-terminally processed] | Early endosome | ||
| Treacle protein (Treacher Collins syndrome protein) | Nucleus, nucleolus | ||
| Neural cell adhesion molecule 2 (N-CAM-2) (NCAM-2) | Cell membrane | ||
| Gelsolin (AGEL) (Actin-depolymerizing factor) (ADF) (Brevin) | Isoform 2: Cytoplasm, cytoskeleton. | ||
| Zinc finger protein 763 | Nucleus | ||
| Vacuolar protein sorting-associated protein 13D | spastic ataxia | ||
| Alpha-actinin-4 (Non-muscle alpha-actinin 4) | Nucleus | ||
| Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4 homolog) (hG4-1) (ErbB3-binding protein 1) | Isoform 1: Cytoplasm | ||
| Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA) | Nucleus. | ||
| Grancalcin | Cytoplasm | ||
| Alpha-parvin (Actopaxin) (CH-ILKBP) (Calponin-like integrin-linked kinase-binding protein) (Matrix-remodeling-associated protein 2) | Cell junction, focal adhesion | ||
| Sorcin (22 kDa protein) (CP-22) (CP22) (V19) | |||
| GRIP1-associated protein 1 (GRASP-1) [Cleaved into: GRASP-1 C-terminal chain (30kDa C-terminus form)] | Early endosome membrane | ||
| Coiled-coil domain-containing protein 183 | |||
| ADP-ribosylation factor-like protein 15 (ADP-ribosylation factor-related protein 2) (ARF-related protein 2) | |||
| THUMP domain-containing protein 3 | |||
| Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FGFR-signaling adaptor SNT2) (Suc1-associated neurotrophic factor target 2) (SNT-2) | Membrane | ||
| Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 6) (LACS 6) | Mitochondrion outer membrane | ||
| Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC) | Cytoplasm, cytoskeleton | ||
| Myosin-11 (Myosin heavy chain 11) (Myosin heavy chain, smooth muscle isoform) (SMMHC) | Melanosome | ||
| Synaptophysin (Major synaptic vesicle protein p38) | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane | ||
| Homeobox protein Hox-C8 (Homeobox protein Hox-3A) | Nucleus. | ||
| Neuroblastoma suppressor of tumorigenicity 1 (DAN domain family member 1) (Protein N03) (Zinc finger protein DAN) | Secreted. | ||
| Selenoprotein N (SelN) | Isoform 2: Endoplasmic reticulum membrane | ||
| Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1) | Parkinson disease | Cytoplasm, perinuclear region | |
| Cytohesin-2 (ARF exchange factor) (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2) | Cell membrane | ||
| Paraneoplastic antigen-like protein 5 (Tumor antigen BJ-HCC-25) | |||
| Histone H2B type 1-H (Histone H2B.j) (H2B/j) | Nucleus | ||
| WD repeat-containing protein 44 (Rabphilin-11) | |||
| Ras-related protein Rab-6B | Golgi apparatus membrane | ||
| Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Solute carrier family 9 member 9) | autism spectrum disorder | Late endosome membrane | |
| FH1/FH2 domain-containing protein 1 (Formin homolog overexpressed in spleen 1) (FHOS) (Formin homology 2 domain-containing protein 1) | |||
| Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) | Cytoplasm | ||
| Protein TESPA1 (Thymocyte-expressed positive selection-associated protein 1) | Cytoplasm | ||
| Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) | Cytoplasm | ||
| Alpha-2-HS-glycoprotein (Alpha-2-Z-globulin) (Ba-alpha-2-glycoprotein) (Fetuin-A) [Cleaved into: Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B] | Secreted. | ||
| SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) | autism spectrum disorder | Cytoplasm | |
| Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3) | Cell membrane | ||
| Lathosterol oxidase (EC 1.14.19.20) (C-5 sterol desaturase) (Delta(7)-sterol 5-desaturase) (Delta(7)-sterol C5(6)-desaturase) (Lathosterol 5-desaturase) (Sterol-C5-desaturase) | Endoplasmic reticulum membrane | ||
| Sorting nexin-25 | Endosome membrane | ||
| Embryonal Fyn-associated substrate (hEFS) (Cas scaffolding protein family member 3) | |||
| Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2) (Short chain dehydrogenase/reductase family 7C member 4) | |||
| Protein FAM110A | Cytoplasm | ||
| tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) (Methyltransferase-like protein 1) (tRNA (guanine(46)-N(7))-methyltransferase) (tRNA(m7G46)-methyltransferase) | Nucleus | ||
| Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c) | Alzheimer disease | Cell membrane | |
| Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (Protein 51C) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2) | |||
| STE20-related kinase adapter protein beta (STRAD beta) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (CALS-21) (ILP-interacting protein) (Pseudokinase ALS2CR2) | lateral sclerosis | Nucleus | |
| Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel) | Nucleus. | ||
| Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1) | Cell membrane | ||
| Exostosin-like 1 (EC 2.4.1.224) (Exostosin-L) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostosis-like protein) | Endoplasmic reticulum membrane | ||
| Serine protease HTRA1 (EC 3.4.21.-) (High-temperature requirement A serine peptidase 1) (L56) (Serine protease 11) | pseudobulbar palsy | Cell membrane | |
| BPI fold-containing family B member 1 (Long palate, lung and nasal epithelium carcinoma-associated protein 1) (von Ebner minor salivary gland protein) (VEMSGP) | Secreted | ||
| Advanced glycosylation end product-specific receptor (Receptor for advanced glycosylation end products) | Isoform 1: Cell membrane | ||
| USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre) | Golgi apparatus | ||
| WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy) | Nucleus membrane | ||
| SHC-transforming protein 3 (Neuronal Shc) (N-Shc) (Protein Rai) (SHC-transforming protein C) (Src homology 2 domain-containing-transforming protein C3) (SH2 domain protein C3) | |||
| Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12) | |||
| Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog) | Nucleus | ||
| Myosin regulatory light chain 2, atrial isoform (MLC-2a) (MLC2a) (Myosin light chain 2a) (Myosin regulatory light chain 7) | |||
| CCA tRNA nucleotidyltransferase 1, mitochondrial (EC 2.7.7.72) (Mitochondrial tRNA nucleotidyl transferase, CCA-adding) (mt CCA-adding enzyme) (mt tRNA CCA-diphosphorylase) (mt tRNA CCA-pyrophosphorylase) (mt tRNA adenylyltransferase) | Mitochondrion | ||
| snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (Proximal sequence element-binding transcription factor subunit delta) (PSE-binding factor subunit delta) (PTF subunit delta) (Small nuclear RNA-activating complex polypeptide 2) (snRNA-activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) | Nucleus. | ||
| MAGUK p55 subfamily member 4 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein) (Discs large homolog 6) | lateral sclerosis | Cytoplasm | |
| Tumor necrosis factor ligand superfamily member 8 (CD30 ligand) (CD30-L) (CD antigen CD153) | Membrane | ||
| Methyltransferase-like protein 27 (Williams-Beuren syndrome chromosomal region 27 protein) | |||
| Rho guanine nucleotide exchange factor 40 (Protein SOLO) | Cytoplasm | ||
| NADH-ubiquinone oxidoreductase chain 4 (EC 7.1.1.2) (NADH dehydrogenase subunit 4) | Mitochondrion membrane | ||
| Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.4.19.12) (Deubiquitinating enzyme 12) (Ubiquitin thioesterase 12) (Ubiquitin-hydrolyzing enzyme 1) (Ubiquitin-specific-processing protease 12) | |||
| SH3 and PX domain-containing protein 2A (Adapter protein TKS5) (Five SH3 domain-containing protein) (SH3 multiple domains protein 1) (Tyrosine kinase substrate with five SH3 domains) | |||
| Fatty acid-binding protein, liver (Fatty acid-binding protein 1) (Liver-type fatty acid-binding protein) (L-FABP) | Cytoplasm. | ||
| Lysoplasmalogenase (EC 3.3.2.2) (Transmembrane protein 86B) | Membrane | ||
| Exostosin-like 3 (EC 2.4.1.223) (EXT-related protein 1) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Hereditary multiple exostoses gene isolog) (Multiple exostosis-like protein 3) (Putative tumor suppressor protein EXTL3) | Endoplasmic reticulum membrane | ||
| Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4) | Membrane | ||
| Glutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.8.6) | Mitochondrion matrix. | ||
| Microtubule-associated protein 2 (MAP-2) | Cytoplasm, cytoskeleton | ||
| Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a) | Cell membrane | ||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta) | Cytoplasm | ||
| Lysoplasmalogenase-like protein TMEM86A (Transmembrane protein 86A) | Membrane | ||
| A-kinase anchor protein 2 (AKAP-2) (AKAP-KL) (Protein kinase A-anchoring protein 2) (PRKA2) | |||
| Metabotropic glutamate receptor 2 (mGluR2) | Cell membrane | ||
| Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4) | autism spectrum disorder | ||
| GTP-binding protein Rit1 (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1) | Cell membrane. | ||
| Ras-specific guanine nucleotide-releasing factor RalGPS2 (Ral GEF with PH domain and SH3-binding motif 2) (RalA exchange factor RalGPS2) | Alzheimer disease | Cytoplasm | |
| Myozenin-1 (Calsarcin-2) (Filamin-, actinin- and telethonin-binding protein) (Protein FATZ) | |||
| Protein phosphatase 1B (EC 3.1.3.16) (Protein phosphatase 2C isoform beta) (PP2C-beta) | Cytoplasm, cytosol | ||
| Spermatogenesis-associated protein 12 (Spermatogenesis-related protein 5) | |||
| Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14) | Cytoplasm, cytoskeleton | ||
| Pregnancy-specific beta-1-glycoprotein 11 (PS-beta-G-11) (PSBG-11) (Pregnancy-specific glycoprotein 11) (Pregnancy-specific beta-1-glycoprotein 13) (PS-beta-G-13) (PSBG-13) (Pregnancy-specific glycoprotein 13) | Secreted | ||
| Oxysterol-binding protein-related protein 6 (ORP-6) (OSBP-related protein 6) | Cytoplasm, cytosol | ||
| Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2) | Cytoplasmic vesicle membrane | ||
| Neurofascin | Cell membrane | ||
| SH3 domain-containing protein 19 (ADAM-binding protein Eve-1) (EEN-binding protein) (EBP) | Cytoplasm | ||
| Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) | Cell membrane | ||
| D(3) dopamine receptor (Dopamine D3 receptor) | Cell membrane | ||
| Haptoglobin (Zonulin) [Cleaved into: Haptoglobin alpha chain; Haptoglobin beta chain] | Secreted. | ||
| Putative E3 ubiquitin-protein ligase UNKL (EC 2.3.2.-) (RING finger protein unkempt-like) (Zinc finger CCCH domain-containing protein 5-like) | |||
| Protein sprouty homolog 4 (Spry-4) | Cytoplasm | ||
| Muscarinic acetylcholine receptor M4 | Cell membrane | ||
| Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma-derived growth factor 2) (HDGF-2) | Nucleus | ||
| Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] | Cytoplasm | ||
| Zinc finger protein 648 | Nucleus | ||
| Ras-related protein Rab-8B | Cell membrane | ||
| Keratin-associated protein 5-2 (Keratin-associated protein 5-8) (Keratin-associated protein 5.2) (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.2) | |||
| Phospholipase A2 (EC 3.1.1.4) (Group IB phospholipase A2) (Phosphatidylcholine 2-acylhydrolase 1B) | Secreted | ||
| Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4) | |||
| Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP) | Cytoplasm | ||
| Disks large-associated protein 2 (DAP-2) (PSD-95/SAP90-binding protein 2) (SAP90/PSD-95-associated protein 2) (SAPAP2) | Cell membrane | ||
| Late cornified envelope protein 1C (Late envelope protein 3) | |||
| Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11) | |||
| Galectin-2 (Gal-2) (Beta-galactoside-binding lectin L-14-II) (HL14) (Lactose-binding lectin 2) (S-Lac lectin 2) | |||
| S-methylmethionine--homocysteine S-methyltransferase BHMT2 (SMM-hcy methyltransferase) (EC 2.1.1.10) (Betaine--homocysteine S-methyltransferase 2) | |||
| Keratin-associated protein 4-4 (Keratin-associated protein 4-13) (Keratin-associated protein 4.13) (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.4) | |||
| Keratin-associated protein 5-3 (Keratin-associated protein 5-9) (Keratin-associated protein 5.3) (Keratin-associated protein 5.9) (UHS KerB-like) (Ultrahigh sulfur keratin-associated protein 5.3) | |||
| Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu) | Cytoplasm | ||
| Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein) (Chorein) | |||
| Slit homolog 1 protein (Slit-1) (Multiple epidermal growth factor-like domains protein 4) (Multiple EGF-like domains protein 4) | Secreted | ||
| SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (Proline-rich synapse-associated protein 1) | autism spectrum disorder | Apical cell membrane | |
| Small integral membrane protein 2 | Membrane | ||
| Disintegrin and metalloproteinase domain-containing protein 15 (ADAM 15) (EC 3.4.24.-) (Metalloprotease RGD disintegrin protein) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15) (MDC-15) (Metargidin) | Endomembrane system | ||
| Microtubule-associated protein 1A (MAP-1A) (Proliferation-related protein p80) [Cleaved into: MAP1A heavy chain; MAP1 light chain LC2] | Cytoplasm, cytoskeleton | ||
| Keratin-associated protein 10-10 (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10) | |||
| Wiskott-Aldrich syndrome protein (WASp) | Cytoplasm, cytoskeleton | ||
| WAS protein family homolog 2 (CXYorf1-like protein on chromosome 2) (Protein FAM39B) | Early endosome membrane | ||
| Zinc finger protein 837 | Nucleus | ||
| Sorting nexin-17 | Cytoplasm | ||
| Calpastatin (Calpain inhibitor) (Sperm BS-17 component) | |||
| Sodium- and chloride-dependent creatine transporter 1 (CT1) (Creatine transporter 1) (Solute carrier family 6 member 8) | autism spectrum disorder | Membrane | |
| Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin-specific peptidase 53) | Cell junction, tight junction | ||
| Uveal autoantigen with coiled-coil domains and ankyrin repeats | Nucleus | ||
| Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1) | Cytoplasm | ||
| 17-beta-hydroxysteroid dehydrogenase type 6 (17-beta-HSD 6) (17-beta-HSD6) (EC 1.1.1.105) (EC 1.1.1.239) (EC 1.1.1.62) (3-alpha->beta-hydroxysteroid epimerase) (3-alpha->beta-HSE) (Oxidative 3-alpha hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 6) | Microsome membrane | ||
| Carbohydrate-responsive element-binding protein (ChREBP) (Class D basic helix-loop-helix protein 14) (bHLHd14) (MLX interactor) (MLX-interacting protein-like) (WS basic-helix-loop-helix leucine zipper protein) (WS-bHLH) (Williams-Beuren syndrome chromosomal region 14 protein) | Nucleus. | ||
| DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135) | Nucleus, nucleolus | ||
| Trifunctional enzyme subunit beta, mitochondrial (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)] | Mitochondrion | ||
| Pituitary homeobox 3 (Homeobox protein PITX3) (Paired-like homeodomain transcription factor 3) | Nucleus | ||
| Proenkephalin-B (Beta-neoendorphin-dynorphin) (Preprodynorphin) [Cleaved into: Alpha-neoendorphin; Beta-neoendorphin; Big dynorphin (Big Dyn); Dynorphin A(1-17) (Dyn-A17) (Dynorphin A); Dynorphin A(1-13); Dynorphin A(1-8); Leu-enkephalin; Rimorphin (Dynorphin B) (Dyn-B) (Dynorphin B(1-13)); Leumorphin (Dynorphin B-29)] | autosomal dominant cerebellar ataxia | Secreted. | |
| Thymosin beta-4 (T beta-4) (Fx) [Cleaved into: Hematopoietic system regulatory peptide (Seraspenide)] | Cytoplasm, cytoskeleton. | ||
| Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain] | Secreted | ||
| Keratin-associated protein 6-1 | |||
| Meckel syndrome type 1 protein | autosomal recessive cerebellar ataxia | ||
| Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20) | Cytoplasm | ||
| Protein OS-9 (Amplified in osteosarcoma 9) | Endoplasmic reticulum lumen | ||
| Sodium-dependent noradrenaline transporter (Norepinephrine transporter) (NET) (Solute carrier family 6 member 2) | Cell membrane | ||
| Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI) | Cytoplasm | ||
| Homeobox protein Hox-C13 (Homeobox protein Hox-3G) | Nucleus. | ||
| Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2) | Cytoplasm | ||
| Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (SP260) (Tumor metastasis-suppressor gene 1 protein) | Nucleus membrane | ||
| Elongation of very long chain fatty acids protein 5 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL5) (ELOVL fatty acid elongase 5) (ELOVL FA elongase 5) (Fatty acid elongase 1) (hELO1) (Very long chain 3-ketoacyl-CoA synthase 5) (Very long chain 3-oxoacyl-CoA synthase 5) | autosomal dominant cerebellar ataxia | Endoplasmic reticulum membrane | |
| SUN domain-containing ossification factor (Membrane protein CH1) (Protein osteopotentia homolog) (SUN-like protein 1) | Rough endoplasmic reticulum membrane | ||
| Homeobox-containing protein 1 (Homeobox telomere-binding protein 1) (Telomere-associated homeobox-containing protein 1) | Nucleus | ||
| Secretin | Secreted. | ||
| Tripartite motif-containing protein 14 | Mitochondrion outer membrane | ||
| Tudor domain-containing protein 15 | |||
| Serine hydrolase-like protein (SHL) (EC 3.1.-.-) | |||
| Aryl hydrocarbon receptor nuclear translocator-like protein 2 (Basic-helix-loop-helix-PAS protein MOP9) (Brain and muscle ARNT-like 2) (CYCLE-like factor) (CLIF) (Class E basic helix-loop-helix protein 6) (bHLHe6) (Member of PAS protein 9) (PAS domain-containing protein 9) | Nucleus | ||
| Solute carrier family 25 member 35 | Mitochondrion inner membrane | ||
| Bardet-Biedl syndrome 1 protein (BBS2-like protein 2) | Cell projection, cilium membrane | ||
| Solute carrier family 35 member E4 | Membrane | ||
| Migration and invasion enhancer 1 (HBV X-transactivated gene 4 protein) (HBV XAg-transactivated protein 4) (Protein C35) | |||
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1) (PDH kinase 1) | Mitochondrion matrix | ||
| Egl nine homolog 2 (EC 1.14.11.29) (Estrogen-induced tag 6) (EIT-6) (HPH-3) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-PH1) (HIF-prolyl hydroxylase 1) (HPH-1) (Prolyl hydroxylase domain-containing protein 1) (PHD1) | Nucleus | ||
| Coagulation factor XII (EC 3.4.21.38) (Hageman factor) (HAF) [Cleaved into: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Coagulation factor XIIa light chain (Beta-factor XIIa part 2)] | Secreted. | ||
| Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (PAPS transporter 1) (Putative MAPK-activating protein PM15) (Putative NF-kappa-B-activating protein 48) (Solute carrier family 35 member B2) | Golgi apparatus membrane | ||
| Basic leucine zipper transcriptional factor ATF-like 2 (B-ATF-2) (Suppressor of AP-1 regulated by IFN) (SARI) | Nucleus | ||
| Aspartate--tRNA ligase, mitochondrial (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS) | autosomal recessive cerebellar ataxia | Mitochondrion matrix | |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K) | Cytoplasm | ||
| Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13) | autosomal dominant cerebellar ataxia | Cytoplasm | |
| Nectin-1 (Herpes virus entry mediator C) (Herpesvirus entry mediator C) (HveC) (Herpesvirus Ig-like receptor) (HIgR) (Nectin cell adhesion molecule 1) (Poliovirus receptor-related protein 1) (CD antigen CD111) | Isoform Alpha: Cell membrane | ||
| Metabotropic glutamate receptor 7 (mGluR7) | Cell membrane | ||
| Collagen alpha-2(I) chain (Alpha-2 type I collagen) | Secreted, extracellular space, extracellular matrix | ||
| Neurexin-1 (Neurexin I-alpha) (Neurexin-1-alpha) | Cell membrane | ||
| Zinc finger CCCH domain-containing protein 3 (Smad-interacting CPSF-like factor) | Nucleus | ||
| Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6) | Membrane | ||
| Protein phosphatase 1 regulatory subunit 14C (Kinase-enhanced PP1 inhibitor) (PKC-potentiated PP1 inhibitory protein) (Serologically defined breast cancer antigen NY-BR-81) | Cytoplasm | ||
| Cell growth regulator with RING finger domain protein 1 (Cell growth regulatory gene 19 protein) (RING finger protein 197) | Nucleus | ||
| Leucine-rich repeats and immunoglobulin-like domains protein 1 (LIG-1) | Cell membrane | ||
| Semaphorin-5A (Semaphorin-F) (Sema F) | autism spectrum disorder | Membrane | |
| Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93) | Cell membrane | ||
| Pro-neuregulin-2, membrane-bound isoform (Pro-NRG2) [Cleaved into: Neuregulin-2 (NRG-2) (Divergent of neuregulin-1) (DON-1) (Neural- and thymus-derived activator for ERBB kinases) (NTAK)] | Pro-neuregulin-2, membrane-bound isoform: Cell membrane | ||
| Proepiregulin [Cleaved into: Epiregulin (EPR)] | Epiregulin: Secreted, extracellular space | ||
| Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4) | Cell membrane | ||
| Disks large homolog 3 (Neuroendocrine-DLG) (Synapse-associated protein 102) (SAP-102) (SAP102) (XLMR) | |||
| NudC domain-containing protein 1 (Chronic myelogenous leukemia tumor antigen 66) (Tumor antigen CML66) | Isoform 1: Cytoplasm | ||
| Uncharacterized protein C22orf15 (Protein N27C7-3) | |||
| Trophinin (MAGE-D3 antigen) | autism spectrum disorder | ||
| Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) | Cell membrane | ||
| Plakophilin-4 (p0071) | Cell junction, desmosome | ||
| Sodium channel protein type 4 subunit alpha (SkM1) (Sodium channel protein skeletal muscle subunit alpha) (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) | Cell membrane | ||
| Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3) | Cell membrane | ||
| Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6) | autism spectrum disorder | Cell membrane | |
| Integrin beta-4 (GP150) (CD antigen CD104) | |||
| Homeobox protein Hox-C4 (Homeobox protein CP19) (Homeobox protein Hox-3E) | Nucleus. | ||
| E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP-like protein) (ILP) (hILP) (Inhibitor of apoptosis protein 3) (IAP-3) (hIAP-3) (hIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP) | |||
| Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2) | |||
| Neurexin-1-beta (Neurexin I-beta) | |||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Cav3.1c) (NBR13) (Voltage-gated calcium channel subunit alpha Cav3.1) | autosomal dominant cerebellar ataxia | Cell membrane | |
| Stromelysin-1 (SL-1) (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) | Secreted, extracellular space, extracellular matrix | ||
| HRAS-like suppressor 3 (HRSL3) (EC 3.1.1.32) (EC 3.1.1.4) (Adipose-specific phospholipase A2) (AdPLA) (Group XVI phospholipase A1/A2) (H-rev 107 protein homolog) (H-REV107) (HREV107-1) (HRAS-like suppressor 1) (HREV107-3) (Renal carcinoma antigen NY-REN-65) | Membrane | ||
| Armadillo repeat-containing protein 12 | |||
| Transmembrane protease serine 2 (EC 3.4.21.-) (Serine protease 10) [Cleaved into: Transmembrane protease serine 2 non-catalytic chain; Transmembrane protease serine 2 catalytic chain] | Cell membrane | ||
| Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130) | Nucleus, nucleolus | ||
| Mediator of RNA polymerase II transcription subunit 31 (Mediator complex subunit 31) (Mediator complex subunit SOH1) (hSOH1) | Nucleus | ||
| Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG) | Nucleus | ||
| Growth/differentiation factor 11 (GDF-11) (Bone morphogenetic protein 11) (BMP-11) | Secreted | ||
| Alpha-1-antitrypsin (Alpha-1 protease inhibitor) (Alpha-1-antiproteinase) (Serpin A1) [Cleaved into: Short peptide from AAT (SPAAT)] | |||
| Ubiquitin-conjugating enzyme E2 J1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J1) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE-1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HsUBC6e) | Endoplasmic reticulum membrane | ||
| Cyclic AMP-dependent transcription factor ATF-6 beta (cAMP-dependent transcription factor ATF-6 beta) (Activating transcription factor 6 beta) (ATF6-beta) (Protein G13) (cAMP response element-binding protein-related protein) (Creb-rp) (cAMP-responsive element-binding protein-like 1) [Cleaved into: Processed cyclic AMP-dependent transcription factor ATF-6 beta] | Endoplasmic reticulum membrane | ||
| Endoplasmic reticulum metallopeptidase 1 (EC 3.4.-.-) (Felix-ina) | Endoplasmic reticulum membrane | ||
| Uncharacterized protein C4orf3 (Hepatitis C virus F protein-transactivated protein 1) (HCV F-transactivated protein 1) | Membrane | ||
| Deleted in autism-related protein 1 | autism spectrum disorder | Secreted | |
| Neuronal growth regulator 1 (IgLON family member 4) | Cell membrane | ||
| Prosaposin receptor GPR37 (Endothelin B receptor-like protein 1) (ETBR-LP-1) (G-protein coupled receptor 37) (Parkin-associated endothelin receptor-like receptor) (PAELR) | Cell membrane | ||
| G-protein coupled receptor 3 (ACCA orphan receptor) | Cell membrane | ||
| Phosphatidylinositol-glycan biosynthesis class F protein (PIG-F) (GPI11 homolog) | Endoplasmic reticulum membrane | ||
| Zinc finger protein 688 | Nucleus | ||
| Protein RFT1 homolog | Membrane | ||
| Anion exchange protein 2 (AE 2) (Anion exchanger 2) (Non-erythroid band 3-like protein) (BND3L) (Solute carrier family 4 member 2) | Membrane | ||
| ADM [Cleaved into: Adrenomedullin (AM); Proadrenomedullin N-20 terminal peptide (ProAM N-terminal 20 peptide) (PAMP) (ProAM-N20)] | Secreted. | ||
| Lysophospholipid acyltransferase 7 (LPLAT 7) (EC 2.3.1.-) (1-acylglycerophosphatidylinositol O-acyltransferase) (EC 2.3.1.n4) (Bladder and breast carcinoma-overexpressed gene 1 protein) (Leukocyte receptor cluster member 4) (Lysophosphatidylinositol acyltransferase) (LPIAT) (Lyso-PI acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 7) (O-acyltransferase domain-containing protein 7) (h-mboa-7) | Membrane | ||
| Transmembrane protein 179B | Membrane | ||
| G-protein coupled receptor 61 (Biogenic amine receptor-like G-protein coupled receptor) | Cell membrane | ||
| Dynactin subunit 4 (Dyn4) (Dynactin subunit p62) | Cytoplasm, cytoskeleton | ||
| Actin-related protein 10 (Actin-related protein 11) (hARP11) | Cytoplasm, cytoskeleton | ||
| Forkhead box protein K1 (Myocyte nuclear factor) (MNF) | Nucleus | ||
| Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1) | Nucleus | ||
| Dynactin subunit 3 (Dynactin complex subunit 22 kDa subunit) (p22) | Cytoplasm | ||
| MutS protein homolog 5 (hMSH5) | |||
| E3 ubiquitin-protein ligase TRIM41 (EC 2.3.2.27) (RING finger-interacting protein with C kinase) (RINCK) (RING-type E3 ubiquitin transferase TRIM41) (Tripartite motif-containing protein 41) | Cytoplasm | ||
| THAP domain-containing protein 1 | Nucleus, nucleoplasm | ||
| Coiled-coil and C2 domain-containing protein 2A | |||
| Ornithine decarboxylase antizyme 1 (AZ1) (ODC-Az) | |||
| Laccase domain-containing protein 1 (Fatty acid metabolism-immunity nexus) | Peroxisome | ||
| Small ubiquitin-related modifier 5 (SUMO-5) (SUMO1 pseudogene 1) (Ubiquitin-like 2) (Ubiquitin-like 6) | Nucleus | ||
| Platelet glycoprotein Ib alpha chain (GP-Ib alpha) (GPIb-alpha) (GPIbA) (Glycoprotein Ibalpha) (Antigen CD42b-alpha) (CD antigen CD42b) [Cleaved into: Glycocalicin] | Membrane | ||
| Phospholipid hydroperoxide glutathione peroxidase (PHGPx) (EC 1.11.1.12) (Glutathione peroxidase 4) (GPx-4) (GSHPx-4) | Isoform Mitochondrial: Mitochondrion | ||
| Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV) | autosomal recessive cerebellar ataxia | Membrane | |
| Testis-specific serine/threonine-protein kinase 3 (TSK-3) (TSSK-3) (Testis-specific kinase 3) (EC 2.7.11.1) (Serine/threonine-protein kinase 22C) | |||
| Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK) | Cytoplasm | ||
| Coiled-coil domain-containing protein 120 | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole | ||
| Gem-associated protein 4 (Gemin-4) (Component of gems 4) (p97) | |||
| Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1) | Secreted, extracellular space, extracellular matrix | ||
| Signal recognition particle 54 kDa protein (SRP54) | Nucleus speckle | ||
| Gem-associated protein 7 (Gemin-7) (SIP3) | Nucleus, nucleoplasm | ||
| Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein) | autism spectrum disorder | Cytoplasm, P-body | |
| Prefoldin subunit 1 | |||
| Gem-associated protein 8 (Gemin-8) (Protein FAM51A1) | Nucleus, gem | ||
| TOX high mobility group box family member 4 (Epidermal Langerhans cell protein LCP1) | Nucleus | ||
| Tomoregulin-2 (TR-2) (Hyperplastic polyposis protein 1) (Transmembrane protein with EGF-like and two follistatin-like domains) | Isoform 1: Membrane | ||
| Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2] | Cell membrane | ||
| Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (PH domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1) | |||
| PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP) | |||
| Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2) | |||
| Phosphatidylinositol 4-kinase type 2-beta (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-beta) (PI4KII-BETA) | |||
| Mitochondrial ribonuclease P catalytic subunit (EC 3.1.26.5) (Mitochondrial ribonuclease P protein 3) (Mitochondrial RNase P protein 3) | Mitochondrion | ||
| GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR) | Cell membrane | ||
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC 1.6.99.3) (EC 7.1.1.2) (Complex I-23kD) (CI-23kD) (NADH-ubiquinone oxidoreductase 23 kDa subunit) (TYKY subunit) | Parkinson disease | Mitochondrion | |
| Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1) | Cell membrane, sarcolemma | ||
| Trefoil factor 3 (Intestinal trefoil factor) (hITF) (Polypeptide P1.B) (hP1.B) | Secreted, extracellular space, extracellular matrix | ||
| S-adenosylhomocysteine hydrolase-like protein 1 (DC-expressed AHCY-like molecule) (IP(3)Rs binding protein released with IP(3)) (IRBIT) (Putative adenosylhomocysteinase 2) (S-adenosyl-L-homocysteine hydrolase 2) (AdoHcyase 2) | Endoplasmic reticulum | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 | Parkinson disease | Nucleus | |
| C-type lectin domain family 4 member G (Liver and lymph node sinusoidal endothelial cell C-type lectin) (LSECtin) | Cell membrane | ||
| Gephyrin [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)] | Cell junction, synapse | ||
| Calfacilitin (TLC domain-containing protein 1) | Cell membrane | ||
| OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1) | Cytoplasm | ||
| Splicing factor U2AF 26 kDa subunit (U2 auxiliary factor 26) (U2 small nuclear RNA auxiliary factor 1-like protein 4) (U2AF1-like 4) (U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3) (U2 small nuclear RNA auxiliary factor 1-like protein 3) (U2AF1-like protein 3) | Nucleus | ||
| Membrane-spanning 4-domains subfamily A member 13 (Testis-expressed transmembrane protein 4) | Membrane | ||
| Protein EFR3 homolog A (Protein EFR3-like) | autism spectrum disorder | Cell membrane | |
| Transmembrane protein 107 | Membrane | ||
| Odontogenic ameloblast-associated protein (Apin) | Secreted | ||
| Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3) | Isoform Alpha: Cell junction | ||
| Osteoclast-stimulating factor 1 | Cytoplasm | ||
| 3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2) | Cytoplasm | ||
| Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Sorbin) | Cytoplasm, perinuclear region | ||
| SH2 domain-containing protein 3C (Novel SH2-containing protein 3) (SH2 domain-containing Eph receptor-binding protein 1) (SHEP1) | Cytoplasm | ||
| Forkhead box protein D4-like 6 (FOXD4-like 6) | Nucleus | ||
| Copper transport protein ATOX1 (Metal transport protein ATX1) | |||
| Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2) | Cell membrane | ||
| Popeye domain-containing protein 2 (Popeye protein 2) | Membrane | ||
| Netrin receptor DCC (Colorectal cancer suppressor) (Immunoglobulin superfamily DCC subclass member 1) (Tumor suppressor protein DCC) | Membrane | ||
| Leukosialin (GPL115) (Galactoglycoprotein) (GALGP) (Leukocyte sialoglycoprotein) (Sialophorin) (CD antigen CD43) [Cleaved into: CD43 cytoplasmic tail (CD43-ct) (CD43ct)] | Membrane | ||
| UPF0692 protein C19orf54 | |||
| Syntaxin-11 | Membrane | ||
| Platelet-activating factor acetylhydrolase IB subunit alpha (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) | Cytoplasm, cytoskeleton | ||
| Regucalcin (RC) (Gluconolactonase) (GNL) (EC 3.1.1.17) (Senescence marker protein 30) (SMP-30) | Cytoplasm | ||
| Neutrophil gelatinase-associated lipocalin (NGAL) (25 kDa alpha-2-microglobulin-related subunit of MMP-9) (Lipocalin-2) (Oncogene 24p3) (Siderocalin) (p25) | Secreted | ||
| Involucrin | |||
| Anoctamin-10 (Transmembrane protein 16K) | autosomal recessive cerebellar ataxia | Cell membrane | |
| Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1) | Secreted, extracellular space | ||
| Regulator of microtubule dynamics protein 3 (RMD-3) (hRMD-3) (Cerebral protein 10) (Protein FAM82A2) (Protein FAM82C) (Protein tyrosine phosphatase-interacting protein 51) (TCPTP-interacting protein 51) | |||
| Fibroblast growth factor 1 (FGF-1) (Acidic fibroblast growth factor) (aFGF) (Endothelial cell growth factor) (ECGF) (Heparin-binding growth factor 1) (HBGF-1) | |||
| Endosomal/lysosomal potassium channel TMEM175 (Transmembrane protein 175) (hTMEM175) | Parkinson disease Lewy body dementia | Endosome membrane | |
| A-kinase anchor protein 12 (AKAP-12) (A-kinase anchor protein 250 kDa) (AKAP 250) (Gravin) (Myasthenia gravis autoantigen) | Cytoplasm, cell cortex | ||
| Transmembrane protease serine 6 (EC 3.4.21.-) (Matriptase-2) | Cell membrane | ||
| Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 4) (LACS 4) | Mitochondrion outer membrane | ||
| Prostaglandin E synthase 2 (Membrane-associated prostaglandin E synthase-2) (mPGE synthase-2) (Microsomal prostaglandin E synthase 2) (mPGES-2) (Prostaglandin-H(2) E-isomerase) (EC 5.3.99.3) [Cleaved into: Prostaglandin E synthase 2 truncated form] | Golgi apparatus membrane | ||
| Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase 2) | |||
| Apolipoprotein L2 (Apolipoprotein L-II) (ApoL-II) | Cytoplasm | ||
| STARD3 N-terminal-like protein (MLN64 N-terminal domain homolog) | Late endosome membrane | ||
| Very-long-chain 3-oxoacyl-CoA reductase (EC 1.1.1.330) (17-beta-hydroxysteroid dehydrogenase 12) (17-beta-HSD 12) (3-ketoacyl-CoA reductase) (KAR) (Estradiol 17-beta-dehydrogenase 12) (EC 1.1.1.62) (Short chain dehydrogenase/reductase family 12C member 1) | Endoplasmic reticulum membrane | ||
| Sesquipedalian-1 (Ses1) (27 kDa inositol polyphosphate phosphatase-interacting protein A) (IPIP27A) (PH domain-containing endocytic trafficking adaptor 1) | Early endosome | ||
| ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor) | Nucleus, PML body | ||
| Mucin-20 (MUC-20) | Secreted | ||
| Gamma-interferon-inducible lysosomal thiol reductase (EC 1.8.-.-) (Gamma-interferon-inducible protein IP-30) (Legumaturain) | Secreted | ||
| B9 domain-containing protein 1 (MKS1-related protein 1) | autosomal recessive cerebellar ataxia | Cytoplasm, cytoskeleton, cilium basal body | |
| CMT1A duplicated region transcript 15 protein | |||
| Beta-1,4-galactosyltransferase 1 (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (EC 2.4.1.-) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1) [Cleaved into: Processed beta-1,4-galactosyltransferase 1] [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)] | Isoform Long: Golgi apparatus, Golgi stack membrane | ||
| Elongator complex protein 3 (hELP3) (EC 2.3.1.48) | Cytoplasm | ||
| SLIT and NTRK-like protein 1 (Leucine-rich repeat-containing protein 12) | Membrane | ||
| Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death) | Endomembrane system | ||
| Low-density lipoprotein receptor (LDL receptor) | Cell membrane | ||
| LisH domain-containing protein ARMC9 (Armadillo repeat-containing protein 9) (Melanoma/melanocyte-specific tumor antigen KU-MEL-1) (NS21) | autosomal recessive cerebellar ataxia | Cytoplasm, cytoskeleton, cilium basal body | |
| Inhibin alpha chain | Secreted. | ||
| Uridine phosphorylase 2 (UPase 2) (UrdPase 2) (EC 2.4.2.3) | |||
| PDZ domain-containing protein 11 (ATPase-interacting PDZ protein) (Plasma membrane calcium ATPase-interacting single-PDZ protein) (PMCA-interacting single-PDZ protein) | Isoform 2: Secreted | ||
| Transmembrane protein 59-like (Brain-specific membrane-anchored protein) | Golgi apparatus membrane | ||
| Retinol dehydrogenase 11 (EC 1.1.1.300) (Androgen-regulated short-chain dehydrogenase/reductase 1) (HCV core-binding protein HCBP12) (Prostate short-chain dehydrogenase/reductase 1) (Retinal reductase 1) (RalR1) (Short chain dehydrogenase/reductase family 7C member 1) | Endoplasmic reticulum membrane | ||
| BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B) | Cell membrane | ||
| Kinesin-like protein KIF1B (Klp) | Cytoplasmic vesicle | ||
| Pyridoxal-dependent decarboxylase domain-containing protein 1 (EC 4.1.1.-) | |||
| Thiamin pyrophosphokinase 1 (hTPK1) (EC 2.7.6.2) (Placental protein 20) (PP20) (Thiamine pyrophosphokinase 1) | episodic ataxia | ||
| Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin) | Apical cell membrane | ||
| Importin subunit alpha-8 (Karyopherin subunit alpha-7) | Nucleus | ||
| Sperm protein associated with the nucleus on the X chromosome N2 (Nuclear-associated protein SPAN-Xn2) (SPANX-N2) (SPANX family member N2) | |||
| Transforming growth factor beta receptor type 3 (TGF-beta receptor type 3) (TGFR-3) (Betaglycan) (Transforming growth factor beta receptor III) (TGF-beta receptor type III) | Secreted | ||
| Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) | Membrane | ||
| Islet cell autoantigen 1-like protein (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 14 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein) | lateral sclerosis | ||
| Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta) | |||
| Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) (QPRTase) | |||
| Protein prenyltransferase alpha subunit repeat-containing protein 1 | |||
| Coronin-1A (Coronin-like protein A) (Clipin-A) (Coronin-like protein p57) (Tryptophan aspartate-containing coat protein) (TACO) | Cytoplasm, cytoskeleton | ||
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4) | |||
| P2Y purinoceptor 6 (P2Y6) | Cell membrane | ||
| G kinase-anchoring protein 1 (cGMP-dependent protein kinase-anchoring protein of 42 kDa) | Golgi apparatus | ||
| Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein 3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase) | |||
| Paraneoplastic antigen Ma3 | Nucleus, nucleolus | ||
| BMP/retinoic acid-inducible neural-specific protein 1 (Deleted in bladder cancer protein 1) | Cytoplasm | ||
| Apolipoprotein B-100 (Apo B-100) [Cleaved into: Apolipoprotein B-48 (Apo B-48)] | Cytoplasm | ||
| Glucosylceramidase (EC 3.2.1.45) (Acid beta-glucosidase) (Alglucerase) (Beta-glucocerebrosidase) (Beta-GC) (D-glucosyl-N-acylsphingosine glucohydrolase) (Imiglucerase) | Parkinson disease Lewy body dementia | Lysosome membrane | |
| Gamma-secretase subunit APH-1B (APH-1b) (Aph-1beta) (Presenilin-stabilization factor-like) | Membrane | ||
| Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) | Secreted | ||
| Urokinase plasminogen activator surface receptor (U-PAR) (uPAR) (Monocyte activation antigen Mo3) (CD antigen CD87) | Cell membrane | ||
| PR domain zinc finger protein 8 (EC 2.1.1.-) (PR domain-containing protein 8) | Lafora disease | Nucleus | |
| Mortality factor 4-like protein 2 (MORF-related gene X protein) (Protein MSL3-2) (Transcription factor-like protein MRGX) | Nucleus. | ||
| Frizzled-7 (Fz-7) (hFz7) (FzE3) | Cell membrane | ||
| Amiloride-sensitive sodium channel subunit beta (Beta-NaCH) (Epithelial Na(+) channel subunit beta) (Beta-ENaC) (ENaCB) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) | Apical cell membrane | ||
| Protein phosphatase 1 regulatory subunit 32 | |||
| Low-density lipoprotein receptor-related protein 6 (LRP-6) | Cell membrane | ||
| Pleckstrin homology domain-containing family B member 2 (PH domain-containing family B member 2) (Evectin-2) | Recycling endosome membrane | ||
| Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) (H-Delta-1) | Apical cell membrane | ||
| Signaling lymphocytic activation molecule (CDw150) (IPO-3) (SLAM family member 1) (CD antigen CD150) | Cell membrane | ||
| Delta(24)-sterol reductase (EC 1.3.1.72) (24-dehydrocholesterol reductase) (3-beta-hydroxysterol Delta-24-reductase) (Diminuto/dwarf1 homolog) (Seladin-1) | Endoplasmic reticulum membrane | ||
| Hemoglobin subunit beta (Beta-globin) (Hemoglobin beta chain) [Cleaved into: LVV-hemorphin-7; Spinorphin] | |||
| Perilipin-2 (Adipophilin) (Adipose differentiation-related protein) (ADRP) | Membrane | ||
| GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (GPI7 homolog) (hGPI7) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G) | autosomal recessive cerebellar ataxia | Endoplasmic reticulum membrane | |
| Eukaryotic translation initiation factor 1A, X-chromosomal (eIF-1A X isoform) (Eukaryotic translation initiation factor 4C) (eIF-4C) | |||
| HLA class I histocompatibility antigen, A-3 alpha chain (MHC class I antigen A*3) | Membrane | ||
| Patatin-like phospholipase domain-containing protein 4 (EC 3.1.1.3) (Protein GS2) | Mitochondrion | ||
| Disabled homolog 1 | autosomal dominant cerebellar ataxia | ||
| PR domain zinc finger protein 1 (EC 2.1.1.-) (BLIMP-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1) (Positive regulatory domain I-binding factor 1) (PRDI-BF1) (PRDI-binding factor 1) | Nucleus | ||
| Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (Cancer Osaka thyroid oncogene) (Proto-oncogene c-Cot) (Serine/threonine-protein kinase cot) (Tumor progression locus 2) (TPL-2) | Cytoplasm | ||
| Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-binding protein 2) (HspBP2) (Hsp70-interacting protein 1) (Hsp70-interacting protein 2) | |||
| GTP-binding protein REM 1 (GTPase-regulating endothelial cell sprouting) (Rad and Gem-like GTP-binding protein 1) | |||
| Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphatidylinositol 3-kinase p100 subunit) (Phosphoinositide-3-kinase class 3) (hVps34) | Midbody | ||
| TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF) | Cytoplasm. | ||
| Protein-lysine methyltransferase METTL21D (EC 2.1.1.-) (Methyltransferase-like protein 21D) (VCP lysine methyltransferase) (VCP-KMT) (Valosin-containing protein lysine methyltransferase) | Cytoplasm | ||
| E3 ubiquitin-protein ligase RNF146 (EC 2.3.2.27) (Dactylidin) (Iduna) (RING finger protein 146) (RING-type E3 ubiquitin transferase RNF146) | |||
| TATA box-binding protein-like protein 1 (TBP-like protein 1) (21 kDa TBP-like protein) (Second TBP of unique DNA protein) (STUD) (TATA box-binding protein-related factor 2) (TBP-related factor 2) (TBP-like factor) (TBP-related protein) | Cytoplasm | ||
| Mitochondrial import inner membrane translocase subunit TIM14 (DnaJ homolog subfamily C member 19) | autosomal recessive cerebellar ataxia | Mitochondrion inner membrane | |
| UBX domain-containing protein 2A (UBX domain-containing protein 4) | |||
| Lysosomal-associated transmembrane protein 4B (Lysosome-associated transmembrane protein 4-beta) | Endomembrane system | ||
| C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1) | |||
| Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) | Golgi apparatus, trans-Golgi network membrane | ||
| Rab GTPase-binding effector protein 2 (Rabaptin-5beta) | Cytoplasm | ||
| Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4) | Cytoplasm | ||
| Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8) | Nucleus, nucleolus | ||
| Exosome complex component CSL4 (Exosome component 1) | Nucleus, nucleolus | ||
| 5'-nucleotidase domain-containing protein 3 (EC 3.1.3.-) (GRP94-neighboring nucleotidase) | |||
| Nuclear nucleic acid-binding protein C1D (hC1D) | Nucleus | ||
| Aggrecan core protein (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) (Chondroitin sulfate proteoglycan 1) [Cleaved into: Aggrecan core protein 2] | Secreted, extracellular space, extracellular matrix | ||
| Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3) | |||
| High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein) | Parkinson disease | ||
| Exosome complex component RRP40 (Exosome component 3) (Ribosomal RNA-processing protein 40) (p10) | pontocerebellar hypoplasia | Cytoplasm | |
| Putative Polycomb group protein ASXL2 (Additional sex combs-like protein 2) | Nucleus | ||
| Single-stranded DNA cytosine deaminase (EC 3.5.4.38) (Activation-induced cytidine deaminase) (AID) (Cytidine aminohydrolase) | Nucleus | ||
| E3 ubiquitin-protein ligase RNF8 (hRNF8) (EC 2.3.2.27) (RING finger protein 8) (RING-type E3 ubiquitin transferase RNF8) | Nucleus | ||
| DIS3-like exonuclease 1 (EC 3.1.13.-) | Cytoplasm | ||
| 39S ribosomal protein L48, mitochondrial (L48mt) (MRP-L48) (Mitochondrial large ribosomal subunit protein mL48) | Mitochondrion | ||
| Eyes absent homolog 2 (EC 3.1.3.48) | Cytoplasm | ||
| Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1) | |||
| Ras-related protein Rab-12 | Recycling endosome membrane | ||
| Keratin-associated protein 13-4 | |||
| Intercellular adhesion molecule 2 (ICAM-2) (CD antigen CD102) | Membrane | ||
| Potassium voltage-gated channel subfamily A member 10 (Voltage-gated potassium channel subunit Kv1.8) | Membrane | ||
| Relaxin-3 receptor 1 (RLN3 receptor 1) (G protein-coupled receptor SALPR) (G-protein coupled receptor GPCR135) (Relaxin family peptide receptor 3) (Somatostatin- and angiotensin-like peptide receptor) | Cell membrane | ||
| Chloride intracellular channel protein 5 | Isoform 1: Cytoplasm, cell cortex | ||
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (Cell adhesion protein SQM1) (Complex I-B18) (CI-B18) (NADH-ubiquinone oxidoreductase B18 subunit) | Mitochondrion inner membrane | ||
| Caspase-10 (CASP-10) (EC 3.4.22.63) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) (ICE-like apoptotic protease 4) [Cleaved into: Caspase-10 subunit p23/17; Caspase-10 subunit p12] | lateral sclerosis multiple sclerosis | ||
| MICOS complex subunit MIC25 (Coiled-coil-helix cristae morphology protein 1) (Coiled-coil-helix-coiled-coil-helix domain-containing protein 6) | Mitochondrion inner membrane | ||
| Protein FAM117B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 13 protein) | lateral sclerosis | ||
| Doublesex- and mab-3-related transcription factor 3 | Nucleus | ||
| Neurexin-3-beta (Neurexin III-beta) [Cleaved into: Neurexin-3-beta, soluble form; Neurexin-3-beta, C-terminal fragment (NRXN3-CTF)] | Membrane | ||
| Neurexin-3 (Neurexin III-alpha) (Neurexin-3-alpha) | Membrane | ||
| Appetite-regulating hormone (Growth hormone secretagogue) (Growth hormone-releasing peptide) (Motilin-related peptide) (Protein M46) [Cleaved into: Ghrelin-27; Ghrelin-28 (Ghrelin); Obestatin] | Secreted. | ||
| Homeobox protein MSX-2 (Homeobox protein Hox-8) | Nucleus. | ||
| Homeobox protein MSX-1 (Homeobox protein Hox-7) (Msh homeobox 1-like protein) | Nucleus. | ||
| NKG2-A/NKG2-B type II integral membrane protein (CD159 antigen-like family member A) (NK cell receptor A) (NKG2-A/B-activating NK receptor) (CD antigen CD159a) | Membrane | ||
| Prenylcysteine oxidase 1 (EC 1.8.3.5) (Prenylcysteine lyase) | Lysosome. | ||
| Nucleoporin NUP188 homolog (hNup188) | Nucleus, nuclear pore complex | ||
| Secretory carrier-associated membrane protein 2 (Secretory carrier membrane protein 2) | Golgi apparatus, trans-Golgi network membrane | ||
| Manganese-transporting ATPase 13A1 (EC 3.6.3.-) | Endoplasmic reticulum membrane | ||
| Pyridoxal phosphate phosphatase PHOSPHO2 (EC 3.1.3.74) | |||
| Myogenesis-regulating glycosidase (EC 3.2.1.-) (Uncharacterized family 31 glucosidase KIAA1161) | Nucleus membrane | ||
| Synaptic vesicular amine transporter (Monoamine transporter) (Solute carrier family 18 member 2) (Vesicular amine transporter 2) (VAT2) | Cytoplasmic vesicle membrane | ||
| Integrator complex subunit 7 (Int7) | Nucleus | ||
| Zinc finger ZZ-type and EF-hand domain-containing protein 1 | |||
| Peroxisomal trans-2-enoyl-CoA reductase (TERP) (EC 1.3.1.38) (2,4-dienoyl-CoA reductase-related protein) (DCR-RP) (HPDHase) (Short chain dehydrogenase/reductase family 29C member 1) (pVI-ARL) | Peroxisome | ||
| Potassium-transporting ATPase alpha chain 2 (EC 3.6.3.10) (Non-gastric H(+)/K(+) ATPase subunit alpha) (Proton pump) | Membrane | ||
| Armadillo repeat-containing protein 10 (Splicing variant involved in hepatocarcinogenesis protein) | Endoplasmic reticulum membrane | ||
| TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP) | Cytoplasm | ||
| Acrosomal protein KIAA1210 | autism spectrum disorder | Cytoplasmic vesicle, secretory vesicle, acrosome | |
| Sperm acrosome membrane-associated protein 1 (Sperm acrosomal membrane-associated protein 32) | Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane | ||
| Late cornified envelope protein 2A (Late envelope protein 9) | |||
| Dual specificity protein phosphatase 10 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5) | Cytoplasm | ||
| Protein N-terminal asparagine amidohydrolase (EC 3.5.1.121) (Protein NH2-terminal asparagine amidohydrolase) (PNAA) (Protein NH2-terminal asparagine deamidase) (PNAD) (Protein N-terminal Asn amidase) (Protein N-terminal asparagine amidase) (Protein NTN-amidase) | Cytoplasm | ||
| Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9) | Early endosome membrane | ||
| Arylsulfatase A (ASA) (EC 3.1.6.8) (Cerebroside-sulfatase) [Cleaved into: Arylsulfatase A component B; Arylsulfatase A component C] | Endoplasmic reticulum | ||
| Golgin subfamily A member 6-like protein 9 | |||
| Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Brain calcium channel I) (BI) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Voltage-gated calcium channel subunit alpha Cav2.1) | episodic ataxia autosomal dominant cerebellar ataxia olivopontocerebellar atrophy | Cell membrane | |
| ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1) | Golgi apparatus, trans-Golgi network membrane | ||
| Beta-secretase 1 (EC 3.4.23.46) (Aspartyl protease 2) (ASP2) (Asp 2) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2) | Cell membrane | ||
| UPF0500 protein C1orf216 | |||
| ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3) | Golgi apparatus, trans-Golgi network membrane | ||
| Beta-secretase 2 (EC 3.4.23.45) (Aspartic-like protease 56 kDa) (Aspartyl protease 1) (ASP1) (Asp 1) (Beta-site amyloid precursor protein cleaving enzyme 2) (Beta-site APP cleaving enzyme 2) (Down region aspartic protease) (DRAP) (Memapsin-1) (Membrane-associated aspartic protease 1) (Theta-secretase) | Cell membrane | ||
| Keratin-associated protein 13-3 | |||
| Keratin-associated protein 3-3 (High sulfur keratin-associated protein 3.3) (Keratin-associated protein 3.3) | |||
| Inactive glycosyltransferase 25 family member 3 (Cerebral endothelial cell adhesion molecule) | Endoplasmic reticulum lumen | ||
| Protein BEAN1 (Brain-expressed protein associating with Nedd4 homolog) (BEAN) | autosomal dominant cerebellar ataxia | Membrane | |
| Zinc finger MYM-type protein 3 (Zinc finger protein 261) | Nucleus | ||
| Adhesion G-protein coupled receptor V1 (ADGRV1) (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1) [Cleaved into: ADGRV1 subunit alpha; ADGRV1 subunit beta] | Cell membrane | ||
| NHL-repeat-containing protein 4 | |||
| Protein WFDC10B | Secreted | ||
| T-cell surface glycoprotein CD1b (CD antigen CD1b) | Cell membrane | ||
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (Complex I-B14.7) (CI-B14.7) (NADH-ubiquinone oxidoreductase subunit B14.7) | Parkinson disease | Mitochondrion inner membrane | |
| Tetra-peptide repeat homeobox protein 1 | Nucleus | ||
| Fibronectin type III domain-containing protein 4 (Fibronectin type III repeat-containing protein 1) | Membrane | ||
| Hyaluronan and proteoglycan link protein 2 (Brain link protein 1) | Secreted, extracellular space, extracellular matrix | ||
| Prefoldin subunit 5 (Myc modulator 1) (c-Myc-binding protein Mm-1) | Isoform 1: Nucleus. | ||
| AT-rich interactive domain-containing protein 2 (ARID domain-containing protein 2) (BRG1-associated factor 200) (BAF200) (Zinc finger protein with activation potential) (Zipzap/p200) | Nucleus. | ||
| Keratin-associated protein 1-5 (High sulfur keratin-associated protein 1.5) (Keratin-associated protein 1.5) | |||
| Late cornified envelope protein 1D (Late envelope protein 4) | |||
| F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx) | Cytoplasm | ||
| Basic leucine zipper and W2 domain-containing protein 2 | |||
| Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26) (Protein deleted in cancer 1) (DICE1) | Nucleus | ||
| Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) | Nucleus | ||
| ATP-sensitive inward rectifier potassium channel 11 (IKATP) (Inward rectifier K(+) channel Kir6.2) (Potassium channel, inwardly rectifying subfamily J member 11) | Membrane | ||
| Eukaryotic translation initiation factor 3 subunit J (eIF3j) (Eukaryotic translation initiation factor 3 subunit 1) (eIF-3-alpha) (eIF3 p35) | Cytoplasm | ||
| Limbic system-associated membrane protein (LSAMP) (IgLON family member 3) | Cell membrane | ||
| Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (Death-associated protein 5) (DAP-5) (p97) | |||
| Laminin subunit beta-4 (Laminin beta-1-related protein) | Secreted, extracellular space, extracellular matrix, basement membrane. | ||
| 5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2) (H91620p) | Parkinson disease | ||
| NADH-ubiquinone oxidoreductase chain 5 (EC 7.1.1.2) (NADH dehydrogenase subunit 5) | Mitochondrion inner membrane | ||
| Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3) | Membrane | ||
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (Complex I-B15) (CI-B15) (NADH-ubiquinone oxidoreductase B15 subunit) | Mitochondrion inner membrane | ||
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (Complex I-SGDH) (CI-SGDH) (NADH-ubiquinone oxidoreductase SGDH subunit) | Mitochondrion inner membrane | ||
| Tubulin epsilon and delta complex protein 1 | |||
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (Complex I-B12) (CI-B12) (NADH-ubiquinone oxidoreductase B12 subunit) | Parkinson disease | Mitochondrion inner membrane | |
| Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) | autosomal recessive cerebellar ataxia spastic ataxia | Cytoplasm | |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (Complex I-B22) (CI-B22) (LYR motif-containing protein 3) (NADH-ubiquinone oxidoreductase B22 subunit) | Parkinson disease | Mitochondrion inner membrane | |
| Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (FROUNT) (Nucleoporin Nup75) (Nucleoporin Nup85) (Pericentrin-1) | Nucleus, nuclear pore complex | ||
| Solute carrier family 26 member 6 (Anion exchange transporter) (Pendrin-like protein 1) (Pendrin-L1) | Cell membrane | ||
| DNA-directed RNA polymerase I subunit RPA34 (A34.5) (Antisense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CAST) (CD3E-associated protein) (RNA polymerase I-associated factor PAF49) | Nucleus, nucleolus | ||
| DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D) (Protein BN51) (RNA polymerase III 47 kDa subunit) (RPC53 homolog) | Nucleus. | ||
| Cancer/testis antigen 47B (Cancer/testis antigen 47.13) (CT47.13) | autism spectrum disorder | ||
| DNA-directed RNA polymerase III subunit RPC8 (RNA polymerase III subunit C8) (DNA-directed RNA polymerase III subunit H) (RNA polymerase III subunit 22.9 kDa subunit) (RPC22.9) | Nucleus. | ||
| DNA-directed RNA polymerases I, II, and III subunit RPABC2 (RNA polymerases I, II, and III subunit ABC2) (DNA-directed RNA polymerase II subunit F) (DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide) (RPABC14.4) (RPB14.4) (RPB6 homolog) (RPC15) | Nucleus | ||
| DNA-directed RNA polymerase III subunit RPC5 (RNA polymerase III subunit C5) (DNA-directed RNA polymerase III 80 kDa polypeptide) | Nucleus. | ||
| DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B) | autosomal recessive cerebellar ataxia | Nucleus | |
| DNA-directed RNA polymerase III subunit RPC10 (RNA polymerase III subunit C10) (DNA-directed RNA polymerase III subunit K) (RNA polymerase III 12.5 kDa subunit) (RPC12.5) (RNA polymerase III subunit C11) (HsC11p) (RPC11) (hRPC11) | Nucleus, nucleolus | ||
| Phakinin (49 kDa cytoskeletal protein) (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 47) (CP47) (Lens fiber cell beaded filament protein CP 49) (CP49) (Lens intermediate filament-like light) (LIFL-L) | Cell membrane | ||
| SH3 domain-binding glutamic acid-rich-like protein | |||
| Amyloid-beta A4 precursor protein-binding family B member 3 (Protein Fe65-like 2) (Fe65L2) | Cytoplasm | ||
| Surfeit locus protein 4 | Endoplasmic reticulum membrane | ||
| C-Jun-amino-terminal kinase-interacting protein 1 (JIP-1) (JNK-interacting protein 1) (Islet-brain 1) (IB-1) (JNK MAP kinase scaffold protein 1) (Mitogen-activated protein kinase 8-interacting protein 1) | Alzheimer disease | Cytoplasm | |
| Probetacellulin [Cleaved into: Betacellulin (BTC)] | Betacellulin: Secreted, extracellular space. | ||
| Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) | Cytoplasm | ||
| Pro-opiomelanocortin (POMC) (Corticotropin-lipotropin) [Cleaved into: NPP; Melanotropin gamma (Gamma-MSH); Potential peptide; Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanocyte-stimulating hormone alpha (Alpha-MSH) (Melanotropin alpha); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanocyte-stimulating hormone beta (Beta-MSH) (Melanotropin beta); Beta-endorphin; Met-enkephalin] | Secreted | ||
| Melanocortin-2 receptor accessory protein 2 (MC2R accessory protein 2) | Cell membrane | ||
| Odontogenesis associated phosphoprotein | Secreted | ||
| Myelin-oligodendrocyte glycoprotein | Isoform 1: Cell membrane | ||
| V-type proton ATPase subunit S1 (V-ATPase subunit S1) (Protein XAP-3) (V-ATPase Ac45 subunit) (V-ATPase S1 accessory protein) (Vacuolar proton pump subunit S1) | Endoplasmic reticulum membrane | ||
| Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr) | Cell membrane | ||
| Leukemia NUP98 fusion partner 1 | |||
| Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB) | Mitochondrion matrix. | ||
| Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1)] | Transforming growth factor alpha: Secreted, extracellular space. | ||
| Autophagy-related protein 9B (APG9-like 2) (Nitric oxide synthase 3-overlapping antisense gene protein) (Protein sONE) | Cytoplasmic vesicle, autophagosome membrane | ||
| Solute carrier family 52, riboflavin transporter, member 3 (Riboflavin transporter 2) (hRFT2) | progressive bulbar palsy lateral sclerosis amyotrophic lateral sclerosis | Apical cell membrane | |
| ADP-ribosylation factor GTPase-activating protein 1 (ARF GAP 1) (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase-activating protein) | Cytoplasm | ||
| Poly [ADP-ribose] polymerase 2 (PARP-2) (hPARP-2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2) | Nucleus | ||
| Homeobox protein Nkx-6.2 (Homeobox protein NK-6 homolog B) | autosomal recessive cerebellar ataxia spastic ataxia | Nucleus | |
| Dual specificity protein phosphatase 21 (EC 3.1.3.16) (EC 3.1.3.48) (Low molecular weight dual specificity phosphatase 21) (LMW-DSP21) | Cytoplasm | ||
| Alpha-actinin-2 (Alpha-actinin skeletal muscle isoform 2) (F-actin cross-linking protein) | Cytoplasm, myofibril, sarcomere, Z line | ||
| Leukocyte immunoglobulin-like receptor subfamily B member 2 (LIR-2) (Leukocyte immunoglobulin-like receptor 2) (CD85 antigen-like family member D) (Immunoglobulin-like transcript 4) (ILT-4) (Monocyte/macrophage immunoglobulin-like receptor 10) (MIR-10) (CD antigen CD85d) | Cell membrane | ||
| Alpha-actinin-3 (Alpha-actinin skeletal muscle isoform 3) (F-actin cross-linking protein) | |||
| Ras-related protein Ral-B | Cell membrane | ||
| Neurogenic locus notch homolog protein 4 (Notch 4) (hNotch4) [Cleaved into: Notch 4 extracellular truncation; Notch 4 intracellular domain] | Cell membrane | ||
| Mannose-1-phosphate guanyltransferase beta (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B) (GTP-mannose-1-phosphate guanylyltransferase beta) | autosomal recessive cerebellar ataxia | Cytoplasm | |
| Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a) (Putative breast adenocarcinoma marker BC-2) (Vacuolar protein sorting-associated protein 2-1) (Vps2-1) (hVps2-1) | Late endosome membrane | ||
| ELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein) | Nucleus speckle | ||
| Little elongation complex subunit 2 (Interactor of little elongator complex ELL subunit 2) (NMDA receptor-regulated protein 2) | Nucleus | ||
| Melanoma-associated antigen B16 (MAGE-B16 antigen) | |||
| NADH-ubiquinone oxidoreductase chain 6 (EC 7.1.1.2) (NADH dehydrogenase subunit 6) | Mitochondrion membrane | ||
| Lysophosphatidic acid receptor 3 (LPA receptor 3) (LPA-3) (Lysophosphatidic acid receptor Edg-7) | Cell membrane | ||
| PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (hPASK) (EC 2.7.11.1) | Cytoplasm | ||
| Elongator complex protein 2 (ELP2) (SHINC-2) (STAT3-interacting protein 1) (StIP1) | Cytoplasm | ||
| Nitric oxide synthase, endothelial (EC 1.14.13.39) (Constitutive NOS) (cNOS) (EC-NOS) (Endothelial NOS) (eNOS) (NOS type III) (NOSIII) | |||
| Inositol hexakisphosphate kinase 3 (InsP6 kinase 3) (EC 2.7.4.21) (Inositol hexaphosphate kinase 3) | Cytoplasm | ||
| Deoxyribonuclease-1 (EC 3.1.21.1) (Deoxyribonuclease I) (DNase I) (Dornase alfa) | Secreted | ||
| DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha) | autosomal recessive cerebellar ataxia | Mitochondrion | |
| DNA polymerase subunit gamma-2, mitochondrial (EC 2.7.7.7) (DNA polymerase gamma accessory 55 kDa subunit) (p55) (Mitochondrial DNA polymerase accessory subunit) (MtPolB) (PolG-beta) | Mitochondrion. | ||
| Endonuclease 8-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (Endonuclease VIII-like 1) (FPG1) (Nei homolog 1) (NEH1) (Nei-like protein 1) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-) | autosomal recessive cerebellar ataxia progressive muscular atrophy | Nucleus | |
| Werner syndrome ATP-dependent helicase (EC 3.6.4.12) (DNA helicase, RecQ-like type 3) (RecQ3) (Exonuclease WRN) (EC 3.1.-.-) (RecQ protein-like 2) | Nucleus, nucleolus | ||
| Aprataxin and PNK-like factor (EC 4.2.99.18) (Apurinic-apyrimidinic endonuclease APLF) (PNK and APTX-like FHA domain-containing protein) (XRCC1-interacting protein 1) | |||
| Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3) | Cell membrane | ||
| Protein inscuteable homolog | Cytoplasm | ||
| Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Atrophin-1-interacting protein 1) (AIP-1) (Atrophin-1-interacting protein A) (Membrane-associated guanylate kinase inverted 2) (MAGI-2) | Cytoplasm | ||
| Spindle and kinetochore-associated protein 1 | Cytoplasm, cytoskeleton, spindle | ||
| Desmoglein-2 (Cadherin family member 5) (HDGC) | Cell membrane | ||
| Transcription elongation factor A protein-like 1 (TCEA-like protein 1) (Nuclear phosphoprotein p21/SIIR) (Transcription elongation factor S-II protein-like 1) | Nucleus. | ||
| TBC1 domain family member 1 | Nucleus | ||
| T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary) | Nucleus | ||
| Rab GTPase-activating protein 1-like | Alzheimer disease | Cytoplasmic vesicle | |
| Lysozyme-like protein 4 (Lysozyme-4) | Secreted | ||
| Contactin-6 (Neural recognition molecule NB-3) (hNB-3) | lateral sclerosis | Cell membrane | |
| Coagulation factor VII (EC 3.4.21.21) (Proconvertin) (Serum prothrombin conversion accelerator) (SPCA) (Eptacog alfa) [Cleaved into: Factor VII light chain; Factor VII heavy chain] | Secreted. | ||
| Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8) | Cytoplasm | ||
| Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) | Cytoplasmic vesicle membrane | ||
| Teneurin-3 (Ten-3) (Protein Odd Oz/ten-m homolog 3) (Tenascin-M3) (Ten-m3) (Teneurin transmembrane protein 3) | Cell membrane | ||
| Transmembrane emp24 domain-containing protein 10 (21 kDa transmembrane-trafficking protein) (S31III125) (S31I125) (Tmp-21-I) (Transmembrane protein Tmp21) (p23) (p24 family protein delta-1) (p24delta1) (p24delta) | Golgi apparatus, cis-Golgi network membrane | ||
| TBC1 domain family member 2A (Armus) (Prostate antigen recognized and identified by SEREX 1) (PARIS-1) | Cytoplasm | ||
| Malate dehydrogenase, mitochondrial (EC 1.1.1.37) | Mitochondrion matrix | ||
| Autophagy-related protein 2 homolog A | Preautophagosomal structure membrane | ||
| Formin-binding protein 1 (Formin-binding protein 17) (hFBP17) | |||
| Autophagy-related protein 16-1 (APG16-like 1) | Cytoplasm | ||
| Protein FAN (Factor associated with neutral sphingomyelinase activation) (Factor associated with N-SMase activation) | |||
| Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B) | Cytoplasm | ||
| Zinc finger protein 471 (EZFIT-related protein 1) | Nucleus | ||
| Ubiquitin-like-conjugating enzyme ATG3 (EC 2.3.2.-) (Autophagy-related protein 3) (APG3-like) (hApg3) (Protein PC3-96) | Cytoplasm | ||
| Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1) | Cell membrane | ||
| Ran-binding protein 6 (RanBP6) | Cytoplasm | ||
| Ubiquitin-like-conjugating enzyme ATG10 (EC 2.3.2.-) (Autophagy-related protein 10) (APG10-like) | Cytoplasm | ||
| Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1) | Cytoplasm, cytosol | ||
| Autophagy-related protein 13 | Cytoplasm, cytosol | ||
| Endophilin-B1 (Bax-interacting factor 1) (Bif-1) (SH3 domain-containing GRB2-like protein B1) | Cytoplasm | ||
| UV radiation resistance-associated gene protein (p63) | Late endosome | ||
| Protein FAM86C1 (EC 2.1.1.-) (Protein FAM86C) | |||
| Enoyl-CoA delta isomerase 2, mitochondrial (EC 5.3.3.8) (DRS-1) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Diazepam-binding inhibitor-related protein 1) (DBI-related protein 1) (Dodecenoyl-CoA isomerase) (Hepatocellular carcinoma-associated antigen 88) (Peroxisomal 3,2-trans-enoyl-CoA isomerase) (pECI) (Renal carcinoma antigen NY-REN-1) | Isoform 1: Mitochondrion | ||
| MAL-like protein (Protein BENE) | Membrane | ||
| Small leucine-rich protein 1 | Membrane | ||
| Atrial natriuretic peptide receptor 3 (Atrial natriuretic peptide clearance receptor) (Atrial natriuretic peptide receptor type C) (ANP-C) (ANPR-C) (NPR-C) | Membrane | ||
| C-type natriuretic peptide [Cleaved into: CNP-22; CNP-29; CNP-53] | Secreted. | ||
| Alpha-2C adrenergic receptor (Alpha-2 adrenergic receptor subtype C4) (Alpha-2C adrenoreceptor) (Alpha-2C adrenoceptor) (Alpha-2CAR) | Cell membrane | ||
| Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B] | Secreted. | ||
| Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) (eIF4E-binding protein 1) (Phosphorylated heat- and acid-stable protein regulated by insulin 1) (PHAS-I) | |||
| Ubiquitin-associated domain-containing protein 1 (UBA domain-containing protein 1) (E3 ubiquitin-protein ligase subunit KPC2) (Glialblastoma cell differentiation-related protein 1) (Kip1 ubiquitination-promoting complex protein 2) | Cytoplasm | ||
| Ethanolamine kinase 1 (EKI 1) (EC 2.7.1.82) | Cytoplasm. | ||
| Dual specificity protein phosphatase 7 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PYST2) | Cytoplasm | ||
| Methionine--tRNA ligase, mitochondrial (EC 6.1.1.10) (Methionyl-tRNA synthetase 2) (Mitochondrial methionyl-tRNA synthetase) (MtMetRS) | autosomal recessive cerebellar ataxia spastic ataxia | Mitochondrion matrix | |
| Homeobox protein Hox-A1 (Homeobox protein Hox-1F) | autism spectrum disorder | Nucleus | |
| E3 ubiquitin-protein ligase UBR2 (EC 2.3.2.27) (N-recognin-2) (RING-type E3 ubiquitin transferase UBR2) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II) | Nucleus | ||
| Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein) | Nucleus, nucleoplasm | ||
| Epidermal growth factor-like protein 6 (EGF-like protein 6) (MAM and EGF domains-containing gene protein) | Secreted, extracellular space, extracellular matrix, basement membrane | ||
| 26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5) (26S proteasome regulatory subunit p55) | |||
| Homer protein homolog 3 (Homer-3) | Cytoplasm | ||
| Chromodomain Y-like protein (CDY-like) (Crotonyl-CoA hydratase) (EC 4.2.1.-) | Isoform 2: Nucleus | ||
| RE1-silencing transcription factor (Neural-restrictive silencer factor) (X2 box repressor) | Nucleus | ||
| MDS1 and EVI1 complex locus protein (Ecotropic virus integration site 1 protein homolog) (EVI-1) (Myelodysplasia syndrome 1 protein) (Myelodysplasia syndrome-associated protein 1) | Nucleus | ||
| DNA-directed RNA polymerase I subunit RPA43 (Twist neighbor protein) | Nucleus, nucleolus | ||
| Cytochrome c oxidase assembly protein COX19 (hCOX19) | Cytoplasm, cytosol | ||
| Zinc finger and BTB domain-containing protein 38 | Nucleus | ||
| Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21) (FHA-HIT-interacting protein) (Nicotinate phosphoribosyltransferase domain-containing protein 1) | Cytoplasm, cytosol | ||
| Noelin-3 (Olfactomedin-3) (Optimedin) | Secreted | ||
| Transmembrane protein adipocyte-associated 1 (Integral membrane protein GPR175) (Transmembrane protein 227) | Membrane | ||
| Matrix metalloproteinase-14 (MMP-14) (EC 3.4.24.80) (MMP-X1) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) | Membrane | ||
| Keratin-associated protein 10-6 (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6) | |||
| Glial cell line-derived neurotrophic factor (hGDNF) (Astrocyte-derived trophic factor) (ATF) | Alzheimer disease | Secreted | |
| Eukaryotic translation initiation factor 5 (eIF-5) | |||
| 3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.-) (EC 1.1.1.30) (Dehydrogenase/reductase SDR family member 6) (Oxidoreductase UCPA) (R-beta-hydroxybutyrate dehydrogenase) (Short chain dehydrogenase/reductase family 15C member 1) | Cytoplasm | ||
| 5'-AMP-activated protein kinase subunit gamma-1 (AMPK gamma1) (AMPK subunit gamma-1) (AMPKg) | |||
| Augurin (Esophageal cancer-related gene 4 protein) | Secreted | ||
| MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1) | Membrane | ||
| Troponin I, slow skeletal muscle (Troponin I, slow-twitch isoform) | |||
| Nucleolar protein 3 (Apoptosis repressor with CARD) (Muscle-enriched cytoplasmic protein) (Myp) (Nucleolar protein of 30 kDa) (Nop30) | Isoform 1: Nucleus, nucleolus | ||
| Dedicator of cytokinesis protein 2 | Endomembrane system | ||
| Cell cycle control protein 50A (P4-ATPase flippase complex beta subunit TMEM30A) (Transmembrane protein 30A) | Membrane | ||
| NHS-like protein 2 | |||
| Collagen alpha-1(XXV) chain (Alzheimer disease amyloid-associated protein) (AMY) (CLAC-P) [Cleaved into: Collagen-like Alzheimer amyloid plaque component (CLAC)] | Membrane | ||
| Acyl-CoA-binding domain-containing protein 4 | |||
| R3H domain-containing protein 2 | Nucleus | ||
| Immediate early response 3-interacting protein 1 | Endoplasmic reticulum membrane | ||
| Zinc finger protein 330 (Nucleolar autoantigen 36) (Nucleolar cysteine-rich protein) | Nucleus | ||
| Protein phosphatase Slingshot homolog 2 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 2) (SSH-2L) (hSSH-2L) | Cytoplasm, cytoskeleton. | ||
| Transcription initiation factor TFIID subunit 11 (TFIID subunit p30-beta) (Transcription initiation factor TFIID 28 kDa subunit) (TAF(II)28) (TAFII-28) (TAFII28) | Nucleus. | ||
| Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) | Golgi apparatus, trans-Golgi network membrane | ||
| Vascular endothelial zinc finger 1 (Putative transcription factor DB1) (Zinc finger protein 161) | Nucleus | ||
| NAD kinase 2, mitochondrial (EC 2.7.1.23) (Mitochondrial NAD kinase) (NAD kinase domain-containing protein 1, mitochondrial) | Mitochondrion | ||
| Adhesion G-protein coupled receptor G2 (G-protein coupled receptor 64) (Human epididymis-specific protein 6) (He6) | autism spectrum disorder | Apical cell membrane | |
| Oxysterol-binding protein-related protein 2 (ORP-2) (OSBP-related protein 2) | |||
| Methionyl-tRNA formyltransferase, mitochondrial (MtFMT) (EC 2.1.2.9) | Parkinson disease | Mitochondrion | |
| Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LPS-induced TNF-alpha factor) (Small integral membrane protein of lysosome/late endosome) (p53-induced gene 7 protein) | multiple system atrophy | Cytoplasm | |
| Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2) | Cytoplasm | ||
| Transcription factor AP-2-delta (AP2-delta) (Activating enhancer-binding protein 2-delta) (Transcription factor AP-2-beta-like 1) | Nucleus | ||
| Zinc finger protein AEBP2 (Adipocyte enhancer-binding protein 2) (AE-binding protein 2) | Nucleus | ||
| Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1) (Lectomedin-2) | Cell membrane | ||
| Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1) | Nucleus | ||
| Protein MAL2 | |||
| NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 (Putative phytoene synthase) | Parkinson disease | ||
| Prolyl endopeptidase-like (EC 3.4.21.-) (Prolylendopeptidase-like) | Cytoplasm, cytosol | ||
| Phytanoyl-CoA dioxygenase, peroxisomal (EC 1.14.11.18) (Phytanic acid oxidase) (Phytanoyl-CoA alpha-hydroxylase) (PhyH) | autosomal recessive cerebellar ataxia | Peroxisome. | |
| Mitochondrial ornithine transporter 1 (Solute carrier family 25 member 15) | episodic ataxia autosomal recessive cerebellar ataxia spastic ataxia | Mitochondrion inner membrane | |
| Non-specific lipid-transfer protein (NSL-TP) (EC 2.3.1.176) (Propanoyl-CoA C-acyltransferase) (SCP-chi) (SCPX) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X) | Cytoplasm | ||
| Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein) | lateral sclerosis | Cytoplasm | |
| Thioredoxin-interacting protein (Thioredoxin-binding protein 2) (Vitamin D3 up-regulated protein 1) | Cytoplasm | ||
| KRAB domain-containing protein ZNF747 | |||
| Eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2) (eIF4E-binding protein 2) | |||
| CKLF-like MARVEL transmembrane domain-containing protein 7 (Chemokine-like factor superfamily member 7) | Membrane | ||
| HEAT repeat-containing protein 5B | |||
| Discoidin, CUB and LCCL domain-containing protein 2 (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1) (Endothelial and smooth muscle cell-derived neuropilin-like protein) | Membrane | ||
| UNC119-binding protein C5orf30 | Cytoplasm | ||
| Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma) | |||
| Septin-7 (CDC10 protein homolog) | Cytoplasm | ||
| Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide-sensitive factor attachment protein gamma) | Membrane | ||
| Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (TRP-1) | Membrane | ||
| Nuclear transcription factor Y subunit gamma (CAAT box DNA-binding protein subunit C) (Nuclear transcription factor Y subunit C) (NF-YC) (Transactivator HSM-1/2) | Nucleus. | ||
| Forkhead box protein N3 (Checkpoint suppressor 1) | Nucleus | ||
| OTU domain-containing protein 3 (EC 3.4.19.12) | |||
| GTP:AMP phosphotransferase AK3, mitochondrial (EC 2.7.4.10) (Adenylate kinase 3) (AK 3) (Adenylate kinase 3 alpha-like 1) | Mitochondrion matrix | ||
| Transmembrane protein 65 | Cell membrane | ||
| Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc kinase) [Includes: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) (EC 3.2.1.183) (UDP-GlcNAc-2-epimerase) (Uridine diphosphate-N-acetylglucosamine-2-epimerase); N-acetylmannosamine kinase (EC 2.7.1.60) (ManAc kinase)] | Cytoplasm | ||
| 5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase) | |||
| Fibronectin type III domain-containing protein 3B (Factor for adipocyte differentiation 104) (HCV NS5A-binding protein 37) | Membrane | ||
| Vertnin | |||
| WNT1-inducible-signaling pathway protein 1 (WISP-1) (CCN family member 4) (Wnt-1-induced secreted protein) | Secreted. | ||
| Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1) | |||
| Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) | Membrane | ||
| Zinc finger protein ZIC 1 (Zinc finger protein 201) (Zinc finger protein of the cerebellum 1) | Nucleus | ||
| Junctophilin-1 (JP-1) (Junctophilin type 1) | Cell membrane | ||
| Zinc finger protein 17 (Zinc finger protein HPF3) (Zinc finger protein KOX10) | Nucleus | ||
| Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1) | Nucleus | ||
| Eukaryotic translation initiation factor 2 subunit 3 (Eukaryotic translation initiation factor 2 subunit gamma X) (eIF-2-gamma X) (eIF-2gX) | |||
| Copper-transporting ATPase 2 (EC 3.6.3.54) (Copper pump 2) (Wilson disease-associated protein) [Cleaved into: WND/140 kDa] | Pick disease | Golgi apparatus, trans-Golgi network membrane | |
| Transcription cofactor vestigial-like protein 3 (Vgl-3) | Nucleus | ||
| Brain-derived neurotrophic factor (BDNF) (Abrineurin) | Parkinson disease | Secreted. | |
| 28S ribosomal protein S10, mitochondrial (MRP-S10) (S10mt) (Mitochondrial small ribosomal subunit protein uS10m) | Mitochondrion | ||
| Ubiquitin-fold modifier 1 | Nucleus | ||
| Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2) | Cell membrane | ||
| SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2) | Nucleus | ||
| Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1) | Cytoplasm, cytoskeleton, cilium basal body | ||
| GTP-binding protein SAR1a (COPII-associated small GTPase) | Endoplasmic reticulum | ||
| Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.12) (EC 1.8.4.14) | Mitochondrion | ||
| Alpha- and gamma-adaptin-binding protein p34 | Cytoplasm, cytosol | ||
| Dermokine (Epidermis-specific secreted protein SK30/SK89) | Secreted | ||
| Putative uncharacterized protein BAALC-AS2 (BAALC antisense RNA 2) (BAALC antisense gene protein 2) (BAALC opposite strand protein) | |||
| Carbamoyl-phosphate synthase [ammonia], mitochondrial (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I) | Mitochondrion | ||
| Peptidyl-prolyl cis-trans isomerase C (PPIase C) (EC 5.2.1.8) (Cyclophilin C) (Rotamase C) | Cytoplasm | ||
| Testis-specific Y-encoded-like protein 1 (TSPY-like protein 1) | Nucleus, nucleolus | ||
| LIM and calponin homology domains-containing protein 1 | Cytoplasm, cytoskeleton, stress fiber | ||
| Ras-related protein Rab-31 (Ras-related protein Rab-22B) | Golgi apparatus, trans-Golgi network | ||
| Proton channel OTOP2 (Otopetrin-2) | Cell membrane | ||
| TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172) | Nucleus. | ||
| Mesogenin-1 (Paraxial mesoderm-specific mesogenin1) (pMesogenin1) (pMsgn1) | Nucleus | ||
| NADH-ubiquinone oxidoreductase chain 3 (EC 7.1.1.2) (NADH dehydrogenase subunit 3) | Parkinson disease | Mitochondrion membrane | |
| Cornifin-A (19 kDa pancornulin) (SPRK) (Small proline-rich protein IA) (SPR-IA) | Cytoplasm. | ||
| Small integral membrane protein 11A | Membrane | ||
| Protein N-terminal glutamine amidohydrolase (EC 3.5.1.122) (Protein NH2-terminal glutamine deamidase) (N-terminal Gln amidase) (Nt(Q)-amidase) (WDYHV motif-containing protein 1) | Cytoplasm, cytosol | ||
| Kinesin-like protein KIF21A (Kinesin-like protein KIF2) (Renal carcinoma antigen NY-REN-62) | Cytoplasm, cytoskeleton | ||
| Ribose-phosphate pyrophosphokinase 2 (EC 2.7.6.1) (PPRibP) (Phosphoribosyl pyrophosphate synthase II) (PRS-II) | |||
| Solute carrier family 25 member 41 | Mitochondrion inner membrane | ||
| ELAV-like protein 1 (Hu-antigen R) (HuR) | Cytoplasm | ||
| Protein GUCD1 (Guanylyl cyclase domain-containing protein 1) (Protein LLN4) | |||
| Metastasis-suppressor KiSS-1 (Kisspeptin-1) [Cleaved into: Metastin (Kisspeptin-54); Kisspeptin-14; Kisspeptin-13; Kisspeptin-10] | Secreted. | ||
| 14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) | Cytoplasm | ||
| Uncharacterized protein KIAA2013 | Membrane | ||
| Progonadoliberin-2 (Progonadoliberin II) [Cleaved into: Gonadoliberin-2 (Gonadoliberin II) (Gonadotropin-releasing hormone II) (GnRH II) (Luliberin II) (Luteinizing hormone-releasing hormone II) (LH-RH II); GnRH-associated peptide 2 (GnRH-associated peptide II)] | Secreted. | ||
| Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) | Huntington disease | Nucleus | |
| Polyubiquitin-C [Cleaved into: Ubiquitin] | Ubiquitin: Cytoplasm | ||
| Translocating chain-associated membrane protein 2 | Membrane | ||
| Mitochondrial folate transporter/carrier (Solute carrier family 25 member 32) | Mitochondrion inner membrane | ||
| Pyridoxine-5'-phosphate oxidase (EC 1.4.3.5) (Pyridoxamine-phosphate oxidase) | |||
| Fibronectin type III and SPRY domain-containing protein 1 (MID1-related protein 1) (Microtubule-associated protein GLFND) | |||
| DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (P1.1-MCM3) | Nucleus | ||
| Microtubule-associated tumor suppressor candidate 2 (Cardiac zipper protein) (Microtubule plus-end tracking protein TIP150) (Tracking protein of 150 kDa) | Cytoplasm, cytoskeleton | ||
| Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (C-type lectin domain family 8 member A) (Lectin-like oxidized LDL receptor 1) (LOX-1) (Lectin-like oxLDL receptor 1) (hLOX-1) (Lectin-type oxidized LDL receptor 1) [Cleaved into: Oxidized low-density lipoprotein receptor 1, soluble form] | Parkinson disease Alzheimer disease | ||
| Melanopsin (Opsin-4) | Cell membrane | ||
| Inactive Ufm1-specific protease 1 (UfSP1) | |||
| Phosphoinositide-3-kinase-interacting protein 1 (Kringle domain-containing protein HGFL) | Cell membrane | ||
| Semaphorin-4D (A8) (BB18) (GR3) (CD antigen CD100) | Cell membrane | ||
| Pleckstrin homology domain-containing family F member 2 (PH domain-containing family F member 2) (Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains) (EAPF) (PH and FYVE domain-containing protein 2) (Phafin-2) (Phafin2) (Zinc finger FYVE domain-containing protein 18) | Early endosome membrane | ||
| Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (ORP-4) (OSBP-related protein 4) | Membrane | ||
| rRNA methyltransferase 1, mitochondrial (EC 2.1.1.-) (16S rRNA (guanosine(1145)-2'-O)-methyltransferase) (16S rRNA [Gm1145] 2'-O-methyltransferase) | Mitochondrion | ||
| Recombining binding protein suppressor of hairless (CBF-1) (J kappa-recombination signal-binding protein) (RBP-J kappa) (RBP-J) (RBP-JK) (Renal carcinoma antigen NY-REN-30) | |||
| Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39) | Nucleus. | ||
| Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin) | Nucleus, nucleolus | ||
| Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (PAM COOH-terminal interactor protein 2) (P-CIP2) (U2AF homology motif kinase 1) | Nucleus | ||
| Isochorismatase domain-containing protein 1 | |||
| Proto-oncogene c-Rel | Nucleus | ||
| Transketolase-like protein 2 (EC 2.2.1.1) | |||
| Syntenin-1 (Melanoma differentiation-associated protein 9) (MDA-9) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18) (Scaffold protein Pbp1) (Syndecan-binding protein 1) | Cell junction, focal adhesion | ||
| DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1) | Golgi apparatus membrane | ||
| Maestro heat-like repeat family member 5 | |||
| Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain] | pseudobulbar palsy | Cell membrane | |
| Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1) | autism spectrum disorder | Nucleus | |
| Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP) | Cytoplasm | ||
| C-type lectin domain family 2 member D (Lectin-like NK cell receptor) (Lectin-like transcript 1) (LLT-1) (Osteoclast inhibitory lectin) | Cell membrane | ||
| FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160) | Nucleus | ||
| Osteopontin (Bone sialoprotein 1) (Nephropontin) (Secreted phosphoprotein 1) (SPP-1) (Urinary stone protein) (Uropontin) | Secreted. | ||
| Lamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Cleaved into: Thymopoietin (TP) (Splenin); Thymopentin (TP5)] | |||
| Lamina-associated polypeptide 2, isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Cleaved into: Thymopoietin (TP) (Splenin); Thymopentin (TP5)] | |||
| Solute carrier family 35 member G1 (Partner of STIM1) (Transmembrane protein 20) | Cell membrane | ||
| Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (GRIP120) (Nuclear p120 ribonucleoprotein) (Scaffold-attachment factor A) (SAF-A) (p120) (pp120) | Nucleus | ||
| Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3) | Nucleus | ||
| Protein YIPF6 (YIP1 family member 6) | Golgi apparatus membrane | ||
| Nuclear receptor corepressor 1 (N-CoR) (N-CoR1) | Nucleus | ||
| Leptin receptor overlapping transcript-like 1 (Endospanin-2) | Membrane | ||
| Bcl-2-associated transcription factor 1 (Btf) (BCLAF1 and THRAP3 family member 1) | Cytoplasm | ||
| High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA) | Cell membrane | ||
| High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility group AT-hook protein 1) (High mobility group protein A1) (High mobility group protein R) | Nucleus | ||
| Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l) | Nucleus | ||
| Vacuolar ATPase assembly integral membrane protein VMA21 (Myopathy with excessive autophagy protein) | Endoplasmic reticulum membrane | ||
| 60S ribosomal protein L10 (Laminin receptor homolog) (Large ribosomal subunit protein uL16) (Protein QM) (Ribosomal protein L10) (Tumor suppressor QM) | autism spectrum disorder | ||
| Decaprenyl-diphosphate synthase subunit 2 (EC 2.5.1.91) (All-trans-decaprenyl-diphosphate synthase subunit 2) (Candidate tumor suppressor protein) (Decaprenyl pyrophosphate synthase subunit 2) | autosomal recessive cerebellar ataxia | Mitochondrion | |
| F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS) | Cytoplasm | ||
| CCAAT/enhancer-binding protein alpha (C/EBP alpha) | Nucleus | ||
| Kelch domain-containing protein 7B | |||
| Histone deacetylase 1 (HD1) (EC 3.5.1.98) | Nucleus | ||
| NAD-dependent protein deacetylase sirtuin-7 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7) | |||
| Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B) | Nucleus | ||
| Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1) (Vesicle APC-binding protein) | Cell membrane | ||
| Receptor of activated protein C kinase 1 (Cell proliferation-inducing gene 21 protein) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Human lung cancer oncogene 7 protein) (HLC-7) (Receptor for activated C kinase) (Small ribosomal subunit protein RACK1) [Cleaved into: Receptor of activated protein C kinase 1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed)] | Cell membrane | ||
| Porimin (Keratinocytes-associated transmembrane protein 3) (KCT-3) (Pro-oncosis receptor inducing membrane injury) (Transmembrane protein 123) | Membrane | ||
| Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6) | Nucleus speckle | ||
| Small ubiquitin-related modifier 3 (SUMO-3) (SMT3 homolog 1) (SUMO-2) (Ubiquitin-like protein SMT3A) (Smt3A) | Cytoplasm | ||
| ORM1-like protein 3 | Endoplasmic reticulum membrane | ||
| Nucleoporin-62 C-terminal-like protein | |||
| Smad nuclear-interacting protein 1 (FHA domain-containing protein SNIP1) | Nucleus | ||
| RNA-binding protein 39 (CAPER alpha) (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1) | |||
| 40S ribosomal protein S2 (40S ribosomal protein S4) (Protein LLRep3) (Small ribosomal subunit protein uS5) | |||
| U4/U6.U5 tri-snRNP-associated protein 1 (SNU66 homolog) (hSnu66) (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (hSART-1) (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (allergen Hom s 1) | Nucleus | ||
| SNW domain-containing protein 1 (Nuclear protein SkiP) (Nuclear receptor coactivator NCoA-62) (Ski-interacting protein) | Nucleus | ||
| Group 10 secretory phospholipase A2 (EC 3.1.1.4) (Group X secretory phospholipase A2) (GX sPLA2) (sPLA2-X) (Phosphatidylcholine 2-acylhydrolase 10) | Secreted | ||
| Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51) | Nucleus | ||
| Poly(A) RNA polymerase, mitochondrial (PAP) (EC 2.7.7.19) (PAP-associated domain-containing protein 1) (Polynucleotide adenylyltransferase) (Terminal uridylyltransferase 1) (TUTase 1) (mtPAP) | autosomal recessive cerebellar ataxia spastic ataxia | Cytoplasm | |
| SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1) | |||
| Histone-lysine N-methyltransferase NSD2 (EC 2.1.1.43) (Multiple myeloma SET domain-containing protein) (MMSET) (Nuclear SET domain-containing protein 2) (Protein trithorax-5) (Wolf-Hirschhorn syndrome candidate 1 protein) | Nucleus | ||
| ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35) | Nucleus | ||
| Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed] | Nucleus | ||
| Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) | Nucleus envelope | ||
| SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal] | |||
| Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.4.19.12) (Deubiquitinating enzyme 33) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (VHL-interacting deubiquitinating enzyme 1) (hVDU1) | Cytoplasm, perinuclear region | ||
| WD repeat and FYVE domain-containing protein 2 (Propeller-FYVE protein) (Prof) (WD40- and FYVE domain-containing protein 2) (Zinc finger FYVE domain-containing protein 22) | Endosome | ||
| Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta) (Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase) | |||
| Pre-mRNA-splicing factor 38A | Nucleus | ||
| C-C motif chemokine 7 (Monocyte chemoattractant protein 3) (Monocyte chemotactic protein 3) (MCP-3) (NC28) (Small-inducible cytokine A7) | Secreted. | ||
| Homeobox protein NANOG (Homeobox transcription factor Nanog) (hNanog) | Nucleus | ||
| TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) | Nucleus | ||
| Tripartite motif-containing protein 26 (EC 2.3.2.27) (Acid finger protein) (AFP) (RING finger protein 95) (Zinc finger protein 173) | Cytoplasm | ||
| Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit) | Nucleus. | ||
| Amyloid-beta A4 precursor protein-binding family B member 1 (Protein Fe65) | Cell membrane | ||
| Neuropeptides B/W receptor type 1 (G-protein coupled receptor 7) | Cell membrane | ||
| Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4) | Nucleus. | ||
| Putative RNA-binding protein Luc7-like 1 (Putative SR protein LUC7B1) (SR+89) | |||
| Sphingomyelin phosphodiesterase (EC 3.1.4.12) (Acid sphingomyelinase) (aSMase) | Pick disease | Lysosome | |
| ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1) | Nucleus | ||
| 40S ribosomal protein SA (37 kDa laminin receptor precursor) (37LRP) (37/67 kDa laminin receptor) (LRP/LR) (67 kDa laminin receptor) (67LR) (Colon carcinoma laminin-binding protein) (Laminin receptor 1) (LamR) (Laminin-binding protein precursor p40) (LBP/p40) (Multidrug resistance-associated protein MGr1-Ag) (NEM/1CHD4) (Small ribosomal subunit protein uS2) | Cell membrane | ||
| Splicing factor 3B subunit 4 (Pre-mRNA-splicing factor SF3b 49 kDa subunit) (Spliceosome-associated protein 49) (SAP 49) | Nucleus | ||
| Golgi phosphoprotein 3 (Coat protein GPP34) (Mitochondrial DNA absence factor) (MIDAS) | Golgi apparatus, Golgi stack membrane | ||
| Golgi phosphoprotein 3-like (GPP34-related protein) | Golgi apparatus, Golgi stack membrane | ||
| Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein) | Nucleus | ||
| Homeobox protein TGIF1 (5'-TG-3'-interacting factor 1) | Nucleus. | ||
| Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (ATP-dependent RNA helicase #46) (DEAH box protein 15) | Nucleus | ||
| CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44) | Cell membrane | ||
| Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3) | Nucleus. | ||
| Peptidyl-prolyl cis-trans isomerase-like 3 (PPIase) (EC 5.2.1.8) (Cyclophilin J) (CyPJ) (Cyclophilin-like protein PPIL3) (Rotamase PPIL3) | |||
| Splicing factor 3A subunit 2 (SF3a66) (Spliceosome-associated protein 62) (SAP 62) | Nucleus | ||
| Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64) | Nucleus, nucleoplasm | ||
| Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162) | Nucleus. | ||
| Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34) | Nucleus | ||
| UBX domain-containing protein 6 (UBX domain-containing protein 1) | Cytoplasm | ||
| Heterogeneous nuclear ribonucleoprotein H3 (hnRNP H3) (Heterogeneous nuclear ribonucleoprotein 2H9) (hnRNP 2H9) | Nucleus | ||
| U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70) | Nucleus speckle | ||
| 40S ribosomal protein S8 (Small ribosomal subunit protein eS8) | Cytoplasm | ||
| Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin) | Parkinson disease | Membrane | |
| CDGSH iron-sulfur domain-containing protein 2 (Endoplasmic reticulum intermembrane small protein) (MitoNEET-related 1 protein) (Miner1) (Nutrient-deprivation autophagy factor-1) (NAF-1) | |||
| WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21) (WW domain-containing-binding protein 4) | Nucleus | ||
| Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X) | Nucleus | ||
| Transcription factor E2F1 (E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1) (Retinoblastoma-binding protein 3) (RBBP-3) (pRB-binding protein E2F-1) | Nucleus | ||
| Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb) | Isoform 1: Cytoplasm | ||
| RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein) | Nucleus | ||
| APC membrane recruitment protein 1 (Amer1) (Protein FAM123B) (Wilms tumor gene on the X chromosome protein) | autism spectrum disorder | ||
| Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain) | Cytoplasm, perinuclear region | ||
| RNA-binding protein 7 (RNA-binding motif protein 7) | Nucleus | ||
| Protein kinase C-binding protein 1 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Rack7) (Zinc finger MYND domain-containing protein 8) | Nucleus | ||
| Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1) | Nucleus membrane | ||
| Collagen alpha-5(IV) chain | Secreted, extracellular space, extracellular matrix, basement membrane. | ||
| Probable RNA-binding protein 23 (RNA-binding motif protein 23) (RNA-binding region-containing protein 4) (Splicing factor SF2) | Nucleus | ||
| Polypyrimidine tract-binding protein 2 (Neural polypyrimidine tract-binding protein) (Neurally-enriched homolog of PTB) (PTB-like protein) | Nucleus | ||
| Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22) | Nucleus | ||
| Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3) | Apical cell membrane | ||
| Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase) | Mitochondrion | ||
| Helicase MOV-10 (EC 3.6.4.13) (Armitage homolog) (Moloney leukemia virus 10 protein) | Cytoplasm, P-body | ||
| Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP) | Nucleus | ||
| Transcription factor IIIB 50 kDa subunit (TFIIIB50) (hTFIIIB50) (B-related factor 2) (BRF-2) (hBRFU) | Nucleus | ||
| Sodium/hydrogen exchanger 1 (APNH) (Na(+)/H(+) antiporter, amiloride-sensitive) (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1) | autosomal recessive cerebellar ataxia | Membrane | |
| Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase) | Cytoplasm | ||
| Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein) | Nucleus. | ||
| Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog) | |||
| Homeobox protein Nkx-2.5 (Cardiac-specific homeobox) (Homeobox protein CSX) (Homeobox protein NK-2 homolog E) | Nucleus | ||
| Histone deacetylase 5 (HD5) (EC 3.5.1.98) (Antigen NY-CO-9) | |||
| Proteasome activator complex subunit 3 (11S regulator complex subunit gamma) (REG-gamma) (Activator of multicatalytic protease subunit 3) (Ki nuclear autoantigen) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma) | Nucleus | ||
| Disintegrin and metalloproteinase domain-containing protein 23 (ADAM 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3) | Cell membrane | ||
| Ubiquitin thioesterase OTU1 (EC 3.4.19.12) (DUBA-8) (HIV-1-induced protease 7) (HIN-7) (HsHIN7) (OTU domain-containing protein 2) | Cytoplasm | ||
| Protein fem-1 homolog A (FEM1a) (FEM1-alpha) (Prostaglandin E receptor 4-associated protein) | Cytoplasm | ||
| Catechol O-methyltransferase domain-containing protein 1 (EC 2.1.1.-) | Membrane | ||
| Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)] | Nucleus | ||
| AMME syndrome candidate gene 1 protein | Nucleus | ||
| Cyclin-T1 (CycT1) (Cyclin-T) | Nucleus | ||
| Nucleoporin SEH1 (GATOR complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein) | Chromosome, centromere, kinetochore | ||
| E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) (p270) | Nucleus | ||
| Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)] | Nucleus membrane | ||
| Midnolin (Midbrain nucleolar protein) | Nucleus, nucleolus | ||
| Gem-associated protein 5 (Gemin5) | Nucleus, nucleoplasm | ||
| Gem-associated protein 2 (Gemin-2) (Component of gems 2) (Survival of motor neuron protein-interacting protein 1) (SMN-interacting protein 1) | |||
| CTD small phosphatase-like protein (CTDSP-like) (EC 3.1.3.16) (Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3) (NIF-like protein) (Nuclear LIM interactor-interacting factor 1) (NLI-interacting factor 1) (Protein YA22) (hYA22) (RBSP3) (Small C-terminal domain phosphatase 3) (SCP3) (Small CTD phosphatase 3) | Nucleus | ||
| Peroxisomal biogenesis factor 19 (33 kDa housekeeping protein) (Peroxin-19) (Peroxisomal farnesylated protein) | Cytoplasm | ||
| Protein SAAL1 (Synoviocyte proliferation-associated in collagen-induced arthritis protein 1) (SPACIA1) | Nucleus | ||
| Zinc finger protein 638 (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL-associated antigen se33-1) (Nuclear protein 220) (Zinc finger matrin-like protein) | Nucleus speckle | ||
| ATPase family AAA domain-containing protein 1 (EC 3.6.1.3) (Thorase) | Peroxisome | ||
| Probable helicase senataxin (EC 3.6.4.-) (Amyotrophic lateral sclerosis 4 protein) (SEN1 homolog) (Senataxin) | autosomal recessive cerebellar ataxia lateral sclerosis amyotrophic lateral sclerosis | Nucleus | |
| Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11) | Cytoplasm | ||
| Adenylosuccinate lyase (ADSL) (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase) | |||
| Protein PAT1 homolog 1 (PAT1-like protein 1) (Protein PAT1 homolog b) (Pat1b) (hPat1b) | |||
| Probable ATP-dependent RNA helicase DDX20 (EC 3.6.4.13) (Component of gems 3) (DEAD box protein 20) (DEAD box protein DP 103) (Gemin-3) | |||
| Serine/threonine-protein kinase 11-interacting protein (LKB1-interacting protein 1) | Cytoplasm | ||
| SURP and G-patch domain-containing protein 1 (RNA-binding protein RBP) (Splicing factor 4) | Nucleus | ||
| Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.43) (HIF-1) (Huntingtin yeast partner B) (Huntingtin-interacting protein 1) (HIP-1) (Huntingtin-interacting protein B) (Lysine N-methyltransferase 3A) (Protein-lysine N-methyltransferase SETD2) (EC 2.1.1.-) (SET domain-containing protein 2) (hSET2) (p231HBP) | autism spectrum disorder | Nucleus | |
| RNA-binding protein PNO1 | Nucleus, nucleolus | ||
| Ubiquinone biosynthesis protein COQ9, mitochondrial | autosomal recessive cerebellar ataxia | Mitochondrion | |
| Zinc finger protein 764 | Nucleus | ||
| Tuftelin-interacting protein 11 (Septin and tuftelin-interacting protein 1) (STIP-1) | Cytoplasm | ||
| Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII) | |||
| Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2) | Cytoplasm, perinuclear region | ||
| Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS) | Cytoplasm | ||
| Serine/threonine-protein phosphatase 4 regulatory subunit 3B (SMEK homolog 2) | Cytoplasm | ||
| Huntingtin-interacting protein 1-related protein (HIP1-related protein) (Huntingtin-interacting protein 12) (HIP-12) | |||
| Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein | Membrane | ||
| HAUS augmin-like complex subunit 7 (26S proteasome-associated UCH37-interacting protein 1) (UCHL5-interacting protein) (X-linked protein STS1769) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97) | Cytoplasm | ||
| Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4) (SR-related and CTD-associated factor 4) | Nucleus | ||
| Serine/threonine-protein phosphatase 4 regulatory subunit 2 | |||
| Pre-B-cell leukemia transcription factor-interacting protein 1 (Hematopoietic PBX-interacting protein) | Cytoplasm, cytoskeleton | ||
| Glycerol-3-phosphate dehydrogenase 1-like protein (GPD1-L) (EC 1.1.1.8) | Cytoplasm | ||
| Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1) | Cytoplasm | ||
| Nestin | |||
| Forkhead box protein G1 (Brain factor 1) (BF-1) (BF1) (Brain factor 2) (BF-2) (BF2) (hBF-2) (Forkhead box protein G1A) (Forkhead box protein G1B) (Forkhead box protein G1C) (Forkhead-related protein FKHL1) (HFK1) (Forkhead-related protein FKHL2) (HFK2) (Forkhead-related protein FKHL3) (HFK3) | Nucleus | ||
| 39S ribosomal protein L45, mitochondrial (L45mt) (MRP-L45) (Mitochondrial large ribosomal subunit protein mL45) | Mitochondrion | ||
| Cell surface hyaluronidase (EC 3.2.1.35) (Cell migration-inducing hyaluronidase 2) (Transmembrane protein 2) | Cell membrane | ||
| Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog) | Nucleus | ||
| Src kinase-associated phosphoprotein 1 (Src family-associated phosphoprotein 1) (Src kinase-associated phosphoprotein of 55 kDa) (SKAP-55) (pp55) | |||
| Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (C-myc promoter-binding protein) (Enolase 1) (MBP-1) (MPB-1) (Non-neural enolase) (NNE) (Phosphopyruvate hydratase) (Plasminogen-binding protein) | Cytoplasm | ||
| NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8) | Nucleus | ||
| Monocarboxylate transporter 5 (MCT 5) (Monocarboxylate transporter 4) (MCT 4) (Solute carrier family 16 member 4) | Cell membrane | ||
| Tektin-1 | Cytoplasm, cytoskeleton, cilium axoneme | ||
| Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11) | Late endosome membrane | ||
| Condensin-2 complex subunit H2 (Chromosome-associated protein H2) (hCAP-H2) (Kleisin-beta) (Non-SMC condensin II complex subunit H2) | Nucleus | ||
| Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1) | Isoform 1: Nucleus | ||
| Nesprin-4 (KASH domain-containing protein 4) (KASH4) (Nuclear envelope spectrin repeat protein 4) | Nucleus outer membrane | ||
| Kunitz-type protease inhibitor 2 (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin) | Membrane | ||
| Deubiquitinase DESI2 (EC 3.4.19.12) (Desumoylating isopeptidase 2) (DeSI-2) (PPPDE peptidase domain-containing protein 1) (Protein FAM152A) | Cytoplasm | ||
| Low-density lipoprotein receptor class A domain-containing protein 4 | Early endosome membrane | ||
| POU domain, class 5, transcription factor 1 (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3) | |||
| Protein RIC-3 (Resistant to inhibitor of cholinesterase 3) | Isoform 1: Endoplasmic reticulum membrane | ||
| CDGSH iron-sulfur domain-containing protein 3, mitochondrial (MitoNEET-related protein 2) (Miner2) (Mitochondrial inner NEET protein) (MiNT) | Mitochondrion | ||
| Probable hydrolase PNKD (EC 3.-.-.-) (Myofibrillogenesis regulator 1) (MR-1) (Paroxysmal nonkinesiogenic dyskinesia protein) (Trans-activated by hepatitis C virus core protein 2) | Isoform 1: Membrane | ||
| Diablo homolog, mitochondrial (Direct IAP-binding protein with low pI) (Second mitochondria-derived activator of caspase) (Smac) | Mitochondrion | ||
| Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3) | Cell junction, adherens junction | ||
| Usher syndrome type-1C protein-binding protein 1 (USH1C-binding protein 1) (AIE-75-binding protein) (MCC-2) (Mutated in colon cancer protein 2) | |||
| Protein INCA1 (Inhibitor of CDK interacting with cyclin A1) | Nucleus | ||
| Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6) | Nucleus | ||
| Ankyrin repeat domain-containing protein 10 | |||
| Prostate-specific antigen (PSA) (EC 3.4.21.77) (Gamma-seminoprotein) (Seminin) (Kallikrein-3) (P-30 antigen) (Semenogelase) | Secreted. | ||
| Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha) | Cytoplasm | ||
| RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta) | |||
| Pumilio homolog 1 (HsPUM) (Pumilio-1) | autosomal dominant cerebellar ataxia | Cytoplasm | |
| Amyloid-like protein 2 (APLP-2) (APPH) (Amyloid protein homolog) (CDEI box-binding protein) (CDEBP) | Cell membrane | ||
| Catenin beta-1 (Beta-catenin) | Cytoplasm | ||
| Ataxin-8 (Protein 1C2) | autosomal dominant cerebellar ataxia | Nucleus | |
| Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5) | Cell junction, adherens junction | ||
| Keratin-associated protein 10-7 (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7) | |||
| Lysosomal protective protein (EC 3.4.16.5) (Carboxypeptidase C) (Carboxypeptidase L) (Cathepsin A) (Protective protein cathepsin A) (PPCA) (Protective protein for beta-galactosidase) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain] | Lysosome. | ||
| Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4) | progressive muscular atrophy spinal muscular atrophy | Nucleus | |
| Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase) (Elastin receptor 1) | Isoform 1: Lysosome | ||
| Signal transducer and activator of transcription 3 (Acute-phase response factor) | Cytoplasm | ||
| Protein NDRG1 (Differentiation-related gene 1 protein) (DRG-1) (N-myc downstream-regulated gene 1 protein) (Nickel-specific induction protein Cap43) (Reducing agents and tunicamycin-responsive protein) (RTP) (Rit42) | |||
| Adapter molecule crk (Proto-oncogene c-Crk) (p38) | Cytoplasm | ||
| Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17) (DHHC-17) | Golgi apparatus membrane | ||
| Amyloid-beta A4 protein (ABPP) (APPI) (APP) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta precursor protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31] | Alzheimer disease | Cell membrane | |
| Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1) | Cell membrane | ||
| Lon protease homolog 2, peroxisomal (EC 3.4.21.53) (Lon protease-like protein 2) (Lon protease 2) (Peroxisomal Lon protease) (pLon) | Peroxisome matrix | ||
| Protein FAM189A2 (Protein X123) | Membrane | ||
| CTD nuclear envelope phosphatase 1 (EC 3.1.3.16) (Serine/threonine-protein phosphatase dullard) | Endoplasmic reticulum membrane | ||
| Transmembrane protein 92 | Membrane | ||
| Guanine nucleotide-binding protein G(i) subunit alpha-1 (Adenylate cyclase-inhibiting G alpha protein) | Nucleus | ||
| Signal recognition particle receptor subunit beta (SR-beta) (Protein APMCF1) | Endoplasmic reticulum membrane | ||
| E3 ubiquitin-protein ligase TRIM8 (EC 2.3.2.27) (Glioblastoma-expressed RING finger protein) (RING finger protein 27) (RING-type E3 ubiquitin transferase TRIM8) (Tripartite motif-containing protein 8) | Cytoplasm | ||
| Testis-expressed protein 264 (Putative secreted protein Zsig11) | Secreted | ||
| RING finger and SPRY domain-containing protein 1 | Secreted | ||
| Interleukin-20 receptor subunit beta (IL-20 receptor subunit beta) (IL-20R-beta) (IL-20RB) (Fibronectin type III domain containing 6) (FNDC6) (IL-20R2) | Membrane | ||
| Cornifelin | |||
| Transport and Golgi organization protein 2 homolog | Golgi apparatus | ||
| Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) | Cytoplasmic vesicle, secretory vesicle | ||
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase Pin1) (PPIase Pin1) (Rotamase Pin1) | Nucleus | ||
| Transforming protein RhoA (Rho cDNA clone 12) (h12) | Cell membrane | ||
| E3 ubiquitin-protein ligase makorin-1 (EC 2.3.2.27) (RING finger protein 61) (RING-type E3 ubiquitin transferase makorin-1) | |||
| Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) | |||
| Ras association domain-containing protein 1 | |||
| RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1) | |||
| RING1 and YY1-binding protein (Apoptin-associating protein 1) (APAP-1) (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1) | Nucleus | ||
| Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)] | |||
| Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase) | Cytoplasm, cytosol | ||
| Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4) | multiple system atrophy | Cytoplasm | |
| Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (Stress-activated protein kinase kinase 4) (SAPK kinase 4) (SAPKK-4) (SAPKK4) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2) | Nucleus | ||
| Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)] | Cytoplasm | ||
| Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) | lateral sclerosis | Cell membrane | |
| N-myc-interactor (Nmi) (N-myc and STAT interactor) | Cytoplasm. | ||
| Antizyme inhibitor 1 (AZI) (AZI1) (Ornithine decarboxylase antizyme inhibitor) | Nucleus | ||
| Dynamin-2 (EC 3.6.5.5) | Cytoplasm | ||
| Lethal(3)malignant brain tumor-like protein 3 (H-l(3)mbt-like protein 3) (L(3)mbt-like protein 3) (MBT-1) | Nucleus | ||
| Beta-defensin 115 (Beta-defensin 15) (DEFB-15) (Defensin, beta 115) | Secreted | ||
| Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (EC 2.7.11.15) (G-protein coupled receptor kinase 2) | Cytoplasm | ||
| Class E basic helix-loop-helix protein 40 (bHLHe40) (Class B basic helix-loop-helix protein 2) (bHLHb2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated by retinoic acid gene 13 protein) | Cytoplasm | ||
| Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src) | Cell membrane | ||
| Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2) | Nucleus | ||
| Amyloid-like protein 1 (APLP) (APLP-1) [Cleaved into: C30] | Cell membrane | ||
| Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit) | Cytoplasm | ||
| Tissue factor (TF) (Coagulation factor III) (Thromboplastin) (CD antigen CD142) | Isoform 1: Membrane | ||
| Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein) | Cell membrane | ||
| Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16) | |||
| Gap junction beta-2 protein (Connexin-26) (Cx26) | Cell membrane | ||
| BAG family molecular chaperone regulator 3 (BAG-3) (Bcl-2-associated athanogene 3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1) | Nucleus | ||
| Protection of telomeres protein 1 (hPot1) (POT1-like telomere end-binding protein) | Nucleus | ||
| Gap junction beta-1 protein (Connexin-32) (Cx32) (GAP junction 28 kDa liver protein) | progressive muscular atrophy | Cell membrane | |
| Lamin-B2 | Nucleus inner membrane | ||
| Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Erythrocyte phospholipid scramblase) (MmTRA1b) | Cell membrane | ||
| Thioredoxin reductase-like selenoprotein T (SelT) (EC 1.8.1.9) | Parkinson disease | Endoplasmic reticulum membrane | |
| Oxysterol-binding protein 1 | Cytoplasm, cytosol | ||
| Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150) | Cytoplasm, cytoskeleton | ||
| Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (CDw130) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130) | Isoform 1: Cell membrane | ||
| Vacuolar protein sorting-associated protein VTA1 homolog (Dopamine-responsive gene 1 protein) (DRG-1) (LYST-interacting protein 5) (LIP5) (SKD1-binding protein 1) (SBP1) | Cytoplasm | ||
| Membrane transport protein XK (Kell complex 37 kDa component) (Kx antigen) (XK-related protein 1) | Huntington disease | Membrane | |
| Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn) | |||
| Amyloid protein-binding protein 2 (Amyloid beta precursor protein-binding protein 2) (APP-BP2) (Protein interacting with APP tail 1) | Nucleus | ||
| Solute carrier family 41 member 1 | Cell membrane | ||
| Cytoplasmic protein NCK1 (NCK adaptor protein 1) (Nck-1) (SH2/SH3 adaptor protein NCK-alpha) | |||
| Histone deacetylase 6 (HD6) (EC 3.5.1.98) | Nucleus | ||
| Transcription factor Sp1 | |||
| TPA-induced transmembrane protein | Endoplasmic reticulum membrane | ||
| Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1) | Nucleus | ||
| U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (hPrp3) (U4/U6 snRNP 90 kDa protein) | Nucleus | ||
| Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1) | Cytoplasm, cytoskeleton | ||
| Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29) | Cell membrane | ||
| Collagen alpha-3(IV) chain (Goodpasture antigen) [Cleaved into: Tumstatin] | |||
| Leukocyte surface antigen CD47 (Antigenic surface determinant protein OA3) (Integrin-associated protein) (IAP) (Protein MER6) (CD antigen CD47) | Cell membrane | ||
| Microfibrillar-associated protein 2 (MFAP-2) (Microfibril-associated glycoprotein 1) (MAGP) (MAGP-1) | Secreted, extracellular space, extracellular matrix. | ||
| von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL) | |||
| Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61) | Cell membrane | ||
| Transmembrane protein 19 | Membrane | ||
| Complement C2 (EC 3.4.21.43) (C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment] | Secreted. | ||
| Protein VAC14 homolog (Tax1-binding protein 2) | Endosome membrane | ||
| Collagen alpha-1(VIII) chain (Endothelial collagen) [Cleaved into: Vastatin] | Secreted, extracellular space, extracellular matrix, basement membrane. | ||
| Keratin-associated protein 10-8 (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8) | |||
| Vinculin (Metavinculin) (MV) | Cell membrane | ||
| ADAMTS-like protein 4 (ADAMTSL-4) (Thrombospondin repeat-containing protein 1) | Secreted, extracellular space, extracellular matrix | ||
| Notch homolog 2 N-terminal-like protein A (Notch homolog 2 N-terminal-like protein) | Secreted | ||
| EGF-containing fibulin-like extracellular matrix protein 2 (Fibulin-4) (FIBL-4) (Protein UPH1) | Secreted. | ||
| Cyclic AMP-responsive element-binding protein 5 (CREB-5) (cAMP-responsive element-binding protein 5) (CRE-BPa) | Nucleus | ||
| Paxillin | Cytoplasm, cytoskeleton | ||
| Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3] | Secreted, extracellular space, extracellular matrix | ||
| Ubiquilin-4 (Ataxin-1 interacting ubiquitin-like protein) (A1Up) (Ataxin-1 ubiquitin-like-interacting protein A1U) (Connexin43-interacting protein of 75 kDa) (CIP75) | lateral sclerosis amyotrophic lateral sclerosis | Nucleus | |
| Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR) | Cytoplasmic vesicle, COPII-coated vesicle | ||
| Adiponectin receptor protein 1 (Progestin and adipoQ receptor family member 1) (Progestin and adipoQ receptor family member I) | Cell membrane | ||
| Keratin, type I cytoskeletal 40 (Cytokeratin-40) (CK-40) (Keratin-40) (K40) (Type I hair keratin Ka36) | |||
| Exopolyphosphatase PRUNE1 (EC 3.6.1.1) (Drosophila-related expressed sequence 17) (DRES-17) (DRES17) (HTcD37) (Protein prune homolog 1) (hPrune) | |||
| Transcription factor Sp4 (SPR-1) | Nucleus. | ||
| Keratin-associated protein 26-1 | |||
| Collagen alpha-1(III) chain | Secreted, extracellular space, extracellular matrix | ||
| Inhibitor of nuclear factor kappa-B kinase-interacting protein (I kappa-B kinase-interacting protein) (IKBKB-interacting protein) (IKK-interacting protein) | Endoplasmic reticulum membrane | ||
| RIPOR family member 3 | |||
| Myelin-associated glycoprotein (Siglec-4a) | Cell membrane | ||
| Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a) | Isoform 1: Cell membrane | ||
| GTPase Era, mitochondrial (H-ERA) (hERA) (Conserved ERA-like GTPase) (CEGA) (ERA-W) (ERA-like protein 1) | |||
| Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP) | Cytoplasm | ||
| Protein FAM76B | Nucleus speckle | ||
| Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) | Endoplasmic reticulum membrane | ||
| Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Tissue transglutaminase) (Transglutaminase C) (TG(C)) (TGC) (TGase C) (Transglutaminase H) (TGase H) (Transglutaminase-2) (TGase-2) | |||
| Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1) | |||
| Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein) | Cytoplasm | ||
| Complement C1q tumor necrosis factor-related protein 2 | Secreted | ||
| Clusterin (Aging-associated gene 4 protein) (Apolipoprotein J) (Apo-J) (Complement cytolysis inhibitor) (CLI) (Complement-associated protein SP-40,40) (Ku70-binding protein 1) (NA1/NA2) (Testosterone-repressed prostate message 2) (TRPM-2) [Cleaved into: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain)] | |||
| CD59 glycoprotein (1F5 antigen) (20 kDa homologous restriction factor) (HRF-20) (HRF20) (MAC-inhibitory protein) (MAC-IP) (MEM43 antigen) (Membrane attack complex inhibition factor) (MACIF) (Membrane inhibitor of reactive lysis) (MIRL) (Protectin) (CD antigen CD59) | |||
| Calmodulin-3 | Cytoplasm, cytoskeleton, spindle | ||
| Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (Coiled-coil domain-containing protein 56) (Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa) | Mitochondrion inner membrane | ||
| Tastin (Trophinin-assisting protein) (Trophinin-associated protein) | Cytoplasm. | ||
| Ras-related protein Rab-6A (Rab-6) | Golgi apparatus membrane | ||
| E3 ubiquitin-protein ligase RFWD3 (EC 2.3.2.27) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201) | Nucleus | ||
| Zinc-activated ligand-gated ion channel (Ligand-gated ion channel zinc-activated 1) (Ligand-gated ion-channel receptor L2) | Cell membrane | ||
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (Complex I-ASHI) (CI-ASHI) (NADH-ubiquinone oxidoreductase ASHI subunit) | Mitochondrion inner membrane | ||
| Mitochondrial import inner membrane translocase subunit Tim21 (TIM21-like protein, mitochondrial) | Mitochondrion membrane | ||
| FLYWCH family member 2 | |||
| Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase) | Mitochondrion outer membrane | ||
| Surfeit locus protein 1 | autosomal recessive cerebellar ataxia | Mitochondrion inner membrane | |
| Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I) | Mitochondrion inner membrane | ||
| Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog) | Cytoplasm | ||
| COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6) (JAB1-containing signalosome subunit 6) (MOV34 homolog) (Vpr-interacting protein) (hVIP) | |||
| Tubulin-folding cofactor B (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B) | Cytoplasm | ||
| Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Protein SITPEC) | Cytoplasm | ||
| Mucolipin-3 (Transient receptor potential channel mucolipin 3) (TRPML3) | Cell membrane | ||
| Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B] | Secreted | ||
| Antileukoproteinase (ALP) (BLPI) (HUSI-1) (Mucus proteinase inhibitor) (MPI) (Protease inhibitor WAP4) (Secretory leukocyte protease inhibitor) (Seminal proteinase inhibitor) (WAP four-disulfide core domain protein 4) | Secreted | ||
| Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4) | autosomal dominant cerebellar ataxia | Endoplasmic reticulum membrane | |
| Protein PML (Promyelocytic leukemia protein) (RING finger protein 71) (Tripartite motif-containing protein 19) | Nucleus | ||
| Cullin-3 (CUL-3) | Nucleus | ||
| HLA class II histocompatibility antigen, DM alpha chain (MHC class II antigen DMA) (Really interesting new gene 6 protein) | |||
| DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1) | autosomal recessive cerebellar ataxia | Nucleus | |
| Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen) | |||
| Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA) | Cell junction, synapse, synaptosome | ||
| Cytosol aminopeptidase (EC 3.4.11.1) (Leucine aminopeptidase 3) (LAP-3) (Leucyl aminopeptidase) (Peptidase S) (Proline aminopeptidase) (EC 3.4.11.5) (Prolyl aminopeptidase) | Cytoplasm. | ||
| Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1) | Late endosome | ||
| Protein S100-A3 (Protein S-100E) (S100 calcium-binding protein A3) | Cytoplasm | ||
| Centrobin (Centrosomal BRCA2-interacting protein) (LYST-interacting protein 8) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole | ||
| Immunoglobulin superfamily containing leucine-rich repeat protein | Secreted | ||
| Desmoglein-4 (Cadherin family member 13) | Cell membrane | ||
| MICOS complex subunit MIC27 (Apolipoprotein O-like) (Protein FAM121A) | Mitochondrion inner membrane | ||
| Dual specificity protein phosphatase 14 (EC 3.1.3.16) (EC 3.1.3.48) (MKP-1-like protein tyrosine phosphatase) (MKP-L) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6) | |||
| Plakophilin-1 (Band 6 protein) (B6P) | Isoform 1: Nucleus | ||
| Leucine-rich repeat-containing protein 15 (Leucine-rich repeat protein induced by beta-amyloid homolog) (hLib) | Membrane | ||
| Hephaestin-like protein 1 (EC 1.-.-.-) | Membrane | ||
| DPY30 domain-containing protein 1 | |||
| Zinc finger protein 609 | Isoform 2: Nucleus | ||
| Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP) | Parkinson disease Lewy body dementia Alzheimer disease | Cytoplasm, cytosol | |
| Huntingtin (Huntington disease protein) (HD protein) | Huntington disease | Cytoplasm | |
| Hyaluronan mediated motility receptor (Intracellular hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD antigen CD168) | Cell surface | ||
| IQ and ubiquitin-like domain-containing protein | |||
| Ras-related C3 botulinum toxin substrate 1 (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1) | Cell membrane | ||
| GTPase KRas (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed] | Cell membrane | ||
| F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA) | progressive muscular atrophy | Cytoplasm | |
| DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4) | Nucleus. | ||
| Heat shock protein beta-2 (HspB2) (DMPK-binding protein) (MKBP) | Cytoplasm | ||
| COX assembly mitochondrial protein 2 homolog | Mitochondrion | ||
| Transcription factor E2F4 (E2F-4) | Nucleus. | ||
| Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2) | Nucleus. | ||
| Protein FAM83D (Spindle protein CHICA) | Cytoplasm | ||
| DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48) | Nucleus | ||
| Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1-alpha) (PPAR-gamma coactivator 1-alpha) (PPARGC-1-alpha) (Ligand effect modulator 6) | Isoform 1: Nucleus | ||
| Activity-dependent neuroprotector homeobox protein (Activity-dependent neuroprotective protein) | autism spectrum disorder | Nucleus | |
| Protocadherin Fat 2 (hFat2) (Cadherin family member 8) (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1) | autosomal dominant cerebellar ataxia | Cell membrane | |
| Echinoderm microtubule-associated protein-like 3 (EMAP-3) | Cytoplasm, cytoskeleton | ||
| NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4) | Endoplasmic reticulum membrane | ||
| Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (EC 2.3.1.48) (Activating transcription factor 2) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (HB16) (Histone acetyltransferase ATF2) (cAMP response element-binding protein CRE-BP1) | |||
| Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog) | Nucleus. | ||
| cAMP-dependent protein kinase inhibitor beta (PKI-beta) | |||
| PILR alpha-associated neural protein (PILR-associating neural protein) (Paired immunoglobin-like type 2 receptor-associating neural protein) | Membrane | ||
| Cleavage and polyadenylation specificity factor subunit 5 (Cleavage and polyadenylation specificity factor 25 kDa subunit) (CPSF 25 kDa subunit) (Cleavage factor Im complex 25 kDa subunit) (CFIm25) (Nucleoside diphosphate-linked moiety X motif 21) (Nudix motif 21) (Nudix hydrolase 21) (Pre-mRNA cleavage factor Im 68 kDa subunit) | Nucleus | ||
| Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (RING-type E3 ubiquitin transferase TRIM27) (Ret finger protein) (Tripartite motif-containing protein 27) | Nucleus | ||
| Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7) | Nucleus | ||
| cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11) | Cytoplasm | ||
| Drebrin (Developmentally-regulated brain protein) | Alzheimer disease | Cytoplasm | |
| Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) | Cytoplasm | ||
| Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155) | Nucleus | ||
| Catenin delta-2 (Delta-catenin) (GT24) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) | autism spectrum disorder | Nucleus | |
| Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein) (MM46) | Endomembrane system | ||
| Mitochondrial dicarboxylate carrier (Solute carrier family 25 member 10) | Mitochondrion inner membrane | ||
| Fragile X mental retardation syndrome-related protein 2 | Cytoplasm. | ||
| Calcineurin B homologous protein 3 (Tescalcin) (TSC) | Nucleus | ||
| Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1) | Nucleus | ||
| CD2 antigen cytoplasmic tail-binding protein 2 (CD2 cytoplasmic domain-binding protein 2) (CD2 tail-binding protein 2) (U5 snRNP 52K protein) (U5-52K) | |||
| Heparan sulfate 2-O-sulfotransferase 1 (2-O-sulfotransferase) (2OST) (EC 2.8.2.-) | Golgi apparatus membrane | ||
| Histone deacetylase 3 (HD3) (EC 3.5.1.98) (RPD3-2) (SMAP45) | Nucleus | ||
| Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein) | Golgi apparatus | ||
| Cdc42-interacting protein 4 (Protein Felic) (Salt tolerant protein) (hSTP) (Thyroid receptor-interacting protein 10) (TR-interacting protein 10) (TRIP-10) | |||
| Amphiphysin | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane | ||
| Polyribonucleotide 5'-hydroxyl-kinase Clp1 (EC 2.7.1.78) (Polyadenylation factor Clp1) (Polynucleotide kinase Clp1) (Pre-mRNA cleavage complex II protein Clp1) | pontocerebellar hypoplasia | Nucleus | |
| Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1) | Cytoplasm | ||
| DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (DNA-directed RNA polymerase II 33 kDa polypeptide) (RPB33) (DNA-directed RNA polymerase II subunit C) (RPB31) | Nucleus | ||
| Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog) (hMtr3) (p11) | Cytoplasm | ||
| Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP) | Cytoplasm | ||
| Growth/differentiation factor 9 (GDF-9) | Secreted | ||
| FUN14 domain-containing protein 2 (Cervical cancer proto-oncogene 3 protein) (HCC-3) (Hepatitis C virus core-binding protein 6) | |||
| E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) | autism spectrum disorder | Cytoplasm | |
| NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)] | Nucleus, PML body | ||
| LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50) | Cytoplasm, cell cortex | ||
| Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP) | Cytoplasm | ||
| Colorectal mutant cancer protein (Protein MCC) | Cell membrane | ||
| Cartilage-associated protein | Secreted, extracellular space, extracellular matrix | ||
| WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase) (Short chain dehydrogenase/reductase family 41C member 1) | autosomal recessive cerebellar ataxia primary cerebellar degeneration | Cytoplasm | |
| Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2) | |||
| Male-specific lethal 3 homolog (Male-specific lethal-3 homolog 1) (Male-specific lethal-3 protein-like 1) (MSL3-like 1) | Nucleus | ||
| 60S acidic ribosomal protein P1 (Large ribosomal subunit protein P1) | |||
| Protein phosphatase 1 regulatory subunit 3F (R3F) | autism spectrum disorder | Membrane | |
| Ataxin-1 (Spinocerebellar ataxia type 1 protein) | autosomal dominant cerebellar ataxia olivopontocerebellar atrophy | Cytoplasm | |
| Proteasome inhibitor PI31 subunit (hPI31) | Cytoplasm | ||
| Sorting nexin-1 | Endosome membrane | ||
| Tetratricopeptide repeat protein 1 (TPR repeat protein 1) | |||
| Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.43) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6) | Nucleus | ||
| Double-stranded RNA-binding protein Staufen homolog 1 | Cytoplasm | ||
| RNA-binding protein 48 | |||
| Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) (GM130 autoantigen) (Golgin-95) | Golgi apparatus, cis-Golgi network membrane | ||
| DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1) | Nucleus | ||
| CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase) (PtdIns synthase) | Endoplasmic reticulum membrane | ||
| Centrosomal protein of 126 kDa | Midbody | ||
| Integrin alpha-4 (CD49 antigen-like family member D) (Integrin alpha-IV) (VLA-4 subunit alpha) (CD antigen CD49d) | Membrane | ||
| SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1) | Cytoplasm. | ||
| Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (PP2A B subunit isoform B'-alpha) (PP2A B subunit isoform B56-alpha) (PP2A B subunit isoform PR61-alpha) (PR61alpha) (PP2A B subunit isoform R5-alpha) | Cytoplasm | ||
| Eukaryotic translation initiation factor 2A (eIF-2A) (65 kDa eukaryotic translation initiation factor 2A) [Cleaved into: Eukaryotic translation initiation factor 2A, N-terminally processed] | |||
| Cytoplasmic dynein 1 intermediate chain 1 (Cytoplasmic dynein intermediate chain 1) (Dynein intermediate chain 1, cytosolic) (DH IC-1) | Cytoplasm | ||
| RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein) | lateral sclerosis amyotrophic lateral sclerosis | Nucleus | |
| Zinc finger protein 346 (Just another zinc finger protein) | Nucleus, nucleolus | ||
| Cleavage and polyadenylation specificity factor subunit 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Cleavage factor Im complex 59 kDa subunit) (CFIm59) (Pre-mRNA cleavage factor Im 59 kDa subunit) | Nucleus | ||
| E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1) (RING-type E3 ubiquitin transferase RING2) | Nucleus | ||
| Alpha-2-macroglobulin (Alpha-2-M) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5) | Secreted | ||
| Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1) | Cytoplasm | ||
| RAD51-associated protein 1 (RAD51-interacting protein) | Nucleus | ||
| Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2) | Cell membrane | ||
| FAD synthase (EC 2.7.7.2) (FAD pyrophosphorylase) (FMN adenylyltransferase) (Flavin adenine dinucleotide synthase) [Includes: Molybdenum cofactor biosynthesis protein-like region; FAD synthase region] | Isoform 1: Mitochondrion matrix | ||
| Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha) | |||
| Pleiotrophin (PTN) (Heparin-binding brain mitogen) (HBBM) (Heparin-binding growth factor 8) (HBGF-8) (Heparin-binding growth-associated molecule) (HB-GAM) (Heparin-binding neurite outgrowth-promoting factor 1) (HBNF-1) (Osteoblast-specific factor 1) (OSF-1) | Secreted | ||
| Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma) | |||
| Glutamate receptor ionotropic, NMDA 2D (GluN2D) (EB11) (Glutamate [NMDA] receptor subunit epsilon-4) (N-methyl D-aspartate receptor subtype 2D) (NMDAR2D) (NR2D) | Cell membrane | ||
| Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1) | Nucleus | ||
| Prolyl 3-hydroxylase 1 (EC 1.14.11.7) (Growth suppressor 1) (Leucine- and proline-enriched proteoglycan 1) (Leprecan-1) | Isoform 1: Endoplasmic reticulum. | ||
| Cleavage stimulation factor subunit 1 (CF-1 50 kDa subunit) (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50) | Nucleus. | ||
| MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2) | Isoform 2: Nucleus, PML body. | ||
| Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta) | Cytoplasm, cytoskeleton | ||
| TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6) | Cytoplasm | ||
| Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1) | Cytoplasm, cytoskeleton | ||
| E3 ubiquitin-protein ligase Itchy homolog (Itch) (EC 2.3.2.26) (Atrophin-1-interacting protein 4) (AIP4) (HECT-type E3 ubiquitin transferase Itchy homolog) (NFE2-associated polypeptide 1) (NAPP1) | Cell membrane | ||
| Retinoic acid receptor RXR-beta (Nuclear receptor subfamily 2 group B member 2) (Retinoid X receptor beta) | Nucleus | ||
| Synphilin-1 (Sph1) (Alpha-synuclein-interacting protein) | Lewy body dementia Parkinson disease | Cytoplasm | |
| Fanconi anemia group J protein (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) | Nucleus | ||
| E3 ubiquitin-protein ligase RNF19A (EC 2.3.2.31) (Double ring-finger protein) (Dorfin) (RING finger protein 19A) (p38) | Membrane | ||
| NIF3-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein) | lateral sclerosis | Cytoplasm | |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i) | Cytoplasm | ||
| E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (Cell proliferation-inducing gene 53 protein) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4) | Cytoplasm | ||
| Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed] | lateral sclerosis amyotrophic lateral sclerosis | Nucleus | |
| Transcription elongation regulator 1 (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) | Nucleus | ||
| Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1) | |||
| Ran GTPase-activating protein 1 (RanGAP1) | Cytoplasm | ||
| Protein timeless homolog (hTIM) | Nucleus | ||
| Peroxiredoxin-4 (EC 1.11.1.15) (Antioxidant enzyme AOE372) (AOE37-2) (Peroxiredoxin IV) (Prx-IV) (Thioredoxin peroxidase AO372) (Thioredoxin-dependent peroxide reductase A0372) | Cytoplasm | ||
| Cancer-associated gene 1 protein (CAGE-1) (Cancer/testis antigen 3) (CT3) | |||
| Vacuolar protein sorting-associated protein 29 (hVPS29) (PEP11 homolog) (Vesicle protein sorting 29) | Cytoplasm | ||
| Beta-crystallin A3 [Cleaved into: Beta-crystallin A3, isoform A1, Delta4 form; Beta-crystallin A3, isoform A1, Delta7 form; Beta-crystallin A3, isoform A1, Delta8 form] | |||
| Alpha-crystallin B chain (Alpha(B)-crystallin) (Heat shock protein beta-5) (HspB5) (Renal carcinoma antigen NY-REN-27) (Rosenthal fiber component) | Cytoplasm | ||
| RNA-binding protein with multiple splicing (RBP-MS) (Heart and RRM expressed sequence) (Hermes) | Nucleus | ||
| RNA-binding motif, single-stranded-interacting protein 3 | Cytoplasm | ||
| THO complex subunit 1 (Tho1) (Nuclear matrix protein p84) (p84N5) (hTREX84) | |||
| Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A) | |||
| Microtubule-associated protein RP/EB family member 2 (APC-binding protein EB2) (End-binding protein 2) (EB2) | Cytoplasm, cytoskeleton | ||
| Hemicentin-1 (Fibulin-6) (FIBL-6) | Secreted, extracellular space, extracellular matrix, basement membrane | ||
| Aquaporin-1 (AQP-1) (Aquaporin-CHIP) (Urine water channel) (Water channel protein for red blood cells and kidney proximal tubule) | Cell membrane | ||
| Zinc finger protein 669 | Nucleus | ||
| MORN repeat-containing protein 4 (Protein 44050) (Retinophilin) | Cytoplasm | ||
| Lens fiber major intrinsic protein (Aquaporin-0) (MIP26) (MP26) | Cell membrane | ||
| Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) | Cytoplasm | ||
| EF-hand domain-containing protein 1 (Myoclonin-1) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Keratin-associated protein 19-3 (GTHRP) (Glycine/tyrosine-rich protein) | |||
| Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B) | Nucleus | ||
| Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26) | Cytoplasm | ||
| Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5) | Cytoplasm | ||
| Calsyntenin-1 (Alcadein-alpha) (Alc-alpha) (Alzheimer-related cadherin-like protein) (Non-classical cadherin XB31alpha) [Cleaved into: Soluble Alc-alpha (SAlc-alpha); CTF1-alpha (C-terminal fragment 1-alpha)] | Endoplasmic reticulum membrane | ||
| DNA repair and recombination protein RAD54-like (EC 3.6.4.-) (RAD54 homolog) (hHR54) (hRAD54) | Nucleus | ||
| Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)] | lateral sclerosis multiple sclerosis multiple system atrophy ... Pick disease amyotrophic lateral sclerosis Alzheimer disease | Endoplasmic reticulum membrane | |
| STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2) | Cytoplasm | ||
| DNA-directed RNA polymerases I, II, and III subunit RPABC4 (RNA polymerases I, II, and III subunit ABC4) (ABC10-alpha) (DNA-directed RNA polymerase II subunit K) (RNA polymerase II 7.0 kDa subunit) (RPB7.0) (RPB10alpha) | Nucleus | ||
| Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.43) (ERG-associated protein with SET domain) (ESET) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (Lysine N-methyltransferase 1E) (SET domain bifurcated 1) | |||
| Proline-rich protein 20D | |||
| E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2) | |||
| CASP8-associated protein 2 (FLICE-associated huge protein) | |||
| Histone H4 | Nucleus | ||
| Carbohydrate sulfotransferase 8 (EC 2.8.2.-) (GalNAc-4-O-sulfotransferase 1) (GalNAc-4-ST1) (GalNAc4ST-1) (N-acetylgalactosamine-4-O-sulfotransferase 1) | Golgi apparatus membrane | ||
| Angio-associated migratory cell protein | Cell membrane | ||
| Histone H2B type 1-M (Histone H2B.e) (H2B/e) | Nucleus | ||
| U6 snRNA-associated Sm-like protein LSm5 | Nucleus | ||
| Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide] | Secreted, extracellular space, extracellular matrix, basement membrane. | ||
| Amyloid-beta A4 precursor protein-binding family A member 2 (Adapter protein X11beta) (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) | |||
| General transcription factor IIF subunit 2 (EC 3.6.4.12) (ATP-dependent helicase GTF2F2) (General transcription factor IIF 30 kDa subunit) (Transcription initiation factor IIF subunit beta) (TFIIF-beta) (Transcription initiation factor RAP30) | Nucleus | ||
| Junctophilin-2 (JP-2) (Junctophilin type 2) | Cell membrane | ||
| RNA-binding Raly-like protein (hRALYL) (Heterogeneous nuclear ribonucleoprotein C-like 3) (hnRNP core protein C-like 3) | |||
| Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein) | Nucleus | ||
| Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53) | Cytoplasm | ||
| Phosducin-like protein (PHLP) | Cell projection, cilium | ||
| Negative elongation factor C/D (NELF-C/D) (TH1-like protein) | Nucleus | ||
| T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) | Cytoplasm | ||
| E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein) | Cytoplasm | ||
| TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2) | Membrane | ||
| Keratin-associated protein 10-9 (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9) | |||
| Adiponectin (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte, C1q and collagen domain-containing protein) (Adipose most abundant gene transcript 1 protein) (apM-1) (Gelatin-binding protein) | Secreted | ||
| Sp110 nuclear body protein (Interferon-induced protein 41/75) (Speckled 110 kDa) (Transcriptional coactivator Sp110) | Nucleus | ||
| Cell division cycle protein 20 homolog B | |||
| E3 ubiquitin-protein ligase KCMF1 (EC 2.3.2.27) (FGF-induced in gastric cancer) (Potassium channel modulatory factor) (PCMF) (RING-type E3 ubiquitin transferase KCMF1) (ZZ-type zinc finger-containing protein 1) | |||
| EKC/KEOPS complex subunit TPRKB (PRPK-binding protein) (TP53RK-binding protein) | Cytoplasm, cytosol | ||
| MIF4G domain-containing protein (SLBP-interacting protein 1) (hSLIP1) | Cytoplasm | ||
| ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DDX19-like protein) (DEAD box protein 19A) | Cytoplasm | ||
| Proliferating cell nuclear antigen (PCNA) (Cyclin) | Nucleus | ||
| Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) | Nucleus | ||
| Germ cell-specific gene 1 protein | Endoplasmic reticulum membrane | ||
| Replication factor C subunit 3 (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit) (RF-C 38 kDa subunit) (RFC38) | Nucleus | ||
| Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) | Cytoplasm | ||
| Ribosomal protein 63, mitochondrial (hMRP63) (Mitochondrial large ribosomal subunit protein mL63) (Mitochondrial ribosomal protein 63) (Mitochondrial ribosomal protein L57) | Mitochondrion | ||
| Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) | Nucleus | ||
| Protein UXT (Androgen receptor trapped clone 27 protein) (ART-27) (Ubiquitously expressed transcript protein) | Isoform 1: Cytoplasm | ||
| Heat shock protein HSP 90-alpha (Heat shock 86 kDa) (HSP 86) (HSP86) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38) | Nucleus | ||
| Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8) | Nucleus | ||
| ATP-dependent DNA helicase DDX11 (EC 3.6.4.12) (CHL1-related protein 1) (hCHLR1) (DEAD/H-box protein 11) (Keratinocyte growth factor-regulated gene 2 protein) (KRG-2) | Nucleus | ||
| U6 snRNA-associated Sm-like protein LSm4 (Glycine-rich protein) (GRP) | Nucleus | ||
| E3 ubiquitin-protein ligase FANCL (EC 2.3.2.27) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43) (RING-type E3 ubiquitin transferase FANCL) | Cytoplasm | ||
| CWF19-like protein 1 (C19L1) | autosomal recessive cerebellar ataxia | ||
| Gigaxonin (Kelch-like protein 16) | Cytoplasm | ||
| Histone H2B type 1-O (Histone H2B.2) (Histone H2B.n) (H2B/n) | Nucleus | ||
| Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog) | Cytoplasm | ||
| PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2) | Cytoplasm | ||
| Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2) | Nucleus | ||
| CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27) | Membrane | ||
| Transcription factor Dp-2 (E2F dimerization partner 2) | Nucleus. | ||
| Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1) | Cell membrane | ||
| Protein lin-9 homolog (HuLin-9) (hLin-9) (Beta subunit-associated regulator of apoptosis) (TUDOR gene similar protein) (Type I interferon receptor beta chain-associated protein) (pRB-associated protein) | Nucleus, nucleoplasm | ||
| Connective tissue growth factor (CCN family member 2) (Hypertrophic chondrocyte-specific protein 24) (Insulin-like growth factor-binding protein 8) (IBP-8) (IGF-binding protein 8) (IGFBP-8) | Secreted, extracellular space, extracellular matrix | ||
| Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333) | |||
| LIM and senescent cell antigen-like-containing domain protein 1 (Particularly interesting new Cys-His protein 1) (PINCH-1) (Renal carcinoma antigen NY-REN-48) | Cell junction, focal adhesion | ||
| Fibulin-1 (FIBL-1) | Secreted, extracellular space, extracellular matrix. | ||
| Putative uncharacterized protein MRGPRG-AS1 (MRGPRG antisense RNA 1) (MRGPRG antisense gene protein 1) | |||
| Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332) | |||
| Actin, cytoplasmic 1 (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed] | Cytoplasm, cytoskeleton | ||
| Vascular endothelial growth factor A (VEGF-A) (Vascular permeability factor) (VPF) | Secreted | ||
| Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) | Cell membrane | ||
| Protein Mpv17 | Mitochondrion inner membrane | ||
| Dehydrogenase/reductase SDR family member 7B (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 32C member 1) | Endoplasmic reticulum membrane | ||
| Transmembrane protein 171 | Membrane | ||
| 5'-nucleotidase (5'-NT) (EC 3.1.3.5) (Ecto-5'-nucleotidase) (CD antigen CD73) | Cell membrane | ||
| Gamma-aminobutyric acid receptor subunit epsilon (GABA(A) receptor subunit epsilon) | Cell junction, synapse, postsynaptic cell membrane | ||
| Protein artemis (EC 3.1.-.-) (DNA cross-link repair 1C protein) (Protein A-SCID) (SNM1 homolog C) (hSNM1C) (SNM1-like protein) | Nucleus | ||
| Transmembrane protein 17 | Cell projection, cilium membrane | ||
| Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C) | lateral sclerosis amyotrophic lateral sclerosis | Endoplasmic reticulum membrane | |
| V-set and immunoglobulin domain-containing protein 4 (Protein Z39Ig) | Membrane | ||
| Tetraspanin-5 (Tspan-5) (Tetraspan NET-4) (Transmembrane 4 superfamily member 9) | Cell membrane | ||
| Phospholipase A-2-activating protein (PLA2P) (PLAP) | Nucleus | ||
| Cortactin-binding protein 2 (CortBP2) | autism spectrum disorder | Cytoplasm, cell cortex | |
| Glutaminyl-peptide cyclotransferase-like protein (EC 2.3.2.5) (Golgi-resident glutaminyl-peptide cyclotransferase) (isoQC) (gQC) | Golgi apparatus membrane | ||
| T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) | Cytoplasm | ||
| Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)] | |||
| Mitochondrial import inner membrane translocase subunit Tim23 | Mitochondrion inner membrane | ||
| Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK) | Cytoplasm | ||
| CTTNBP2 N-terminal-like protein | Cytoplasm, cytoskeleton, stress fiber | ||
| Histone H2B type 1-J (Histone H2B.1) (Histone H2B.r) (H2B/r) | Nucleus | ||
| T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15) | Cytoplasm | ||
| Origin recognition complex subunit 6 | Nucleus. | ||
| Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C) | Cytoplasm | ||
| Striatin-4 (Zinedin) | Cytoplasm | ||
| Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1) | |||
| Diamine acetyltransferase 2 (EC 2.3.1.57) (Polyamine N-acetyltransferase 2) (Spermidine/spermine N(1)-acetyltransferase 2) (Thialysine N-epsilon-acetyltransferase) | |||
| T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) | Cytoplasm, cytosol | ||
| Lysosomal Pro-X carboxypeptidase (EC 3.4.16.2) (Angiotensinase C) (Lysosomal carboxypeptidase C) (Proline carboxypeptidase) (Prolylcarboxypeptidase) (PRCP) | Lysosome. | ||
| Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A subunit A isoform PR65-beta) (PP2A subunit A isoform R1-beta) | |||
| Proline-rich protein 20C | |||
| Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16) | Cytoplasm | ||
| DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1) | Early endosome membrane | ||
| Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1) | Cytoplasm | ||
| Thymidylate synthase (TS) (TSase) (EC 2.1.1.45) | Nucleus | ||
| TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83) | Cytoplasm | ||
| SAGA-associated factor 29 (Coiled-coil domain-containing protein 101) (SAGA complex-associated factor 29) | Nucleus | ||
| DNA replication complex GINS protein PSF3 (GINS complex subunit 3) | Nucleus | ||
| Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.43) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a) | Nucleus | ||
| Enkurin domain-containing protein 1 | |||
| Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1) | |||
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (Complex I-B17) (CI-B17) (NADH-ubiquinone oxidoreductase B17 subunit) | Mitochondrion inner membrane | ||
| Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2) | Cell membrane | ||
| Mirror-image polydactyly gene 1 protein | |||
| TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1) | Nucleus | ||
| Complex I assembly factor TMEM126B, mitochondrial (Transmembrane protein 126B) | Mitochondrion membrane | ||
| Coiled-coil domain-containing protein 102B | |||
| TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3) | Cytoplasm | ||
| Sperm-associated antigen 5 (Astrin) (Deepest) (Mitotic spindle-associated protein p126) (MAP126) | Cytoplasm | ||
| DNA repair protein XRCC2 (X-ray repair cross-complementing protein 2) | Nucleus | ||
| Cerebellar degeneration-related protein 2 (Major Yo paraneoplastic antigen) (Paraneoplastic cerebellar degeneration-associated antigen) | |||
| Coiled-coil domain-containing protein 136 (Nasopharyngeal carcinoma-associated gene 6 protein) | Cytoplasmic vesicle, secretory vesicle, acrosome membrane | ||
| 14-3-3 protein epsilon (14-3-3E) | Nucleus | ||
| PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma) | Cytoplasm | ||
| MyoD family inhibitor (Myogenic repressor I-mf) | Nucleus | ||
| Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (GTP-binding and GTPase-activating protein 2) (GGAP2) (Phosphatidylinositol 3-kinase enhancer) (PIKE) | Isoform 1: Cytoplasm | ||
| Paraneoplastic antigen Ma1 (37 kDa neuronal protein) (Neuron- and testis-specific protein 1) | Nucleus, nucleolus | ||
| Tripartite motif-containing protein 54 (Muscle-specific RING finger protein) (MuRF) (Muscle-specific RING finger protein 3) (MuRF-3) (MuRF3) (RING finger protein 30) | Cytoplasm, cytoskeleton | ||
| Protein/nucleic acid deglycase DJ-1 (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase) (Oncogene DJ1) (Parkinson disease protein 7) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) | Parkinson disease lateral sclerosis amyotrophic lateral sclerosis | Cell membrane | |
| Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3) | Cytoplasm | ||
| TATA box-binding protein-associated factor RNA polymerase I subunit C (RNA polymerase I-specific TBP-associated factor 110 kDa) (TAFI110) (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C) | Nucleus. | ||
| UBX domain-containing protein 11 (Colorectal tumor-associated antigen COA-1) (Socius) (UBX domain-containing protein 5) | Cytoplasm, cytoskeleton | ||
| WD repeat-containing protein 62 | Nucleus | ||
| Probable E3 ubiquitin-protein ligase makorin-3 (EC 2.3.2.27) (RING finger protein 63) (RING-type E3 ubiquitin transferase makorin-3) (Zinc finger protein 127) | |||
| FGGY carbohydrate kinase domain-containing protein (EC 2.7.1.-) | lateral sclerosis amyotrophic lateral sclerosis | ||
| Coiled-coil domain-containing protein 85B (Hepatitis delta antigen-interacting protein A) (Delta-interacting protein A) | Nucleus | ||
| Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52) | Cytoplasm, perinuclear region | ||
| Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2) | Nucleus | ||
| Brain-enriched guanylate kinase-associated protein | Cytoplasm | ||
| Growth/differentiation factor 5 (GDF-5) (Bone morphogenetic protein 14) (BMP-14) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Lipopolysaccharide-associated protein 4) (LAP-4) (LPS-associated protein 4) (Radotermin) | Secreted | ||
| Centrosomal protein of 70 kDa (Cep70) (p10-binding protein) | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome | ||
| Ribosomal RNA processing protein 1 homolog B (RRP1-like protein B) | Nucleus, nucleolus | ||
| Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] | Low-density lipoprotein receptor-related protein 1 85 kDa subunit: Cell membrane | ||
| Gastric intrinsic factor (Intrinsic factor) (IF) (INF) | Secreted. | ||
| Vitamin D-binding protein (DBP) (VDB) (Gc protein-derived macrophage activating factor) (Gc-MAF) (GcMAF) (Gc-globulin) (Group-specific component) (Gc) (Vitamin D-binding protein-macrophage activating factor) (DBP-maf) | Secreted | ||
| Protein CutA (Acetylcholinesterase-associated protein) (Brain acetylcholinesterase putative membrane anchor) | |||
| Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1) (hEFG1) | Mitochondrion |
| Disease | Proteins | Cross Reference |
|---|---|---|
| 0 | ||
| 20 PTPRC CASP8 MBP MYO1E SIAE TNR1A BC11B WT1 CASPA LMNB1 ... FLNA FCRL3 PAR3L TAU CD24 LUM PSN1 CP4V2 CAD13 IL7RA | DI-02604 DOID:2377 D009103 | |
| 0 | DOID:0060215 D002549 | |
| 0 | DOID:636 D017590 | |
| 1 PANK2 | DI-02126 DOID:3981 D006211 | |
| 38 TBA4A CI072 KIF5A ROA1 DCTN1 SETX MATR3 NFH FIG4 ATX2 ... TFG CHM2B SODC T106B ANX11 PROF1 OPTN ALS2 TERA PARK7 FGGY TAU VAPB NEK1 TRPM7 UBQL2 TBK1 ANGI CHC10 ERBB4 | DI-00107 DOID:332 D000690 | |
| 3 NOTC3 HTRA1 TAU | DI-02215 DOID:12680 D020828 | |
| 67 TBA4A C2CD6 CI072 CASP8 KIF5A ROA1 CFLAR DCTN1 SETX ICA1L ... RAPH1 MATR3 NFH NBEL1 FIG4 STRAB BC11B MPP4 ATX2 FEZF2 TFG DOC2B CHM2B CASPA SODC T106B ANX11 FLNA PROF1 OPTN | DOID:230 D016472 | |
| 1 S52A3 | DOID:681 D010244 | |
| 0 | DOID:683 D009443 | |
| 13 TF2H2 ANDR DCTN1 SMN GUSP1 BICD2 SERF1 BIRC1 HSPB3 TRPV4 ... KHDR1 ATP7A SERF2 | DI-01055 DOID:12377 D009134 | |
| 23 CAN3 ANDR ASAH1 BSCL2 DCTN1 MYPN SC5A7 CAV3 FLNC TBCE ... ACTS CXB1 PURA1 FHL1 FBX38 TYDP1 TRPV4 CHC10 DNJB2 MYP0 COQ7 FRG1 ATP7A | DOID:318 D009134 | |
| 0 | DOID:14332 D010301 | |
| 77 B9D2 C19L1 SL9A1 IF140 TOP3A XRCC1 PNKP NPHP1 WWOX MPPB ... S17A5 COQ8A TPP1 SPTN2 FRM4A GRID2 TYDP2 DPOG1 SETX WDR73 SCYL1 CAH8 ARMC9 REPS1 UBA5 APTX GPAA1 ATG5 ORNT1 L2HDH | DI-01061 DOID:0050950 | |
| 10 GTR1 HUTU ORNT1 KCNA1 CACB4 FRIL ODP2 TPK1 CAC1A EAA1 | DI-00475 DOID:963 C580065 | |
| 17 GTR1 MYPR ABD12 ORNT1 PLPL6 UCHL1 SACS ITM2B ARGI1 PAPD1 ... AFG32 SYMM VAMP1 KIF1C VP13D NKX62 TBB4A | DI-04137 DOID:0050952 | |
| 41 NEP COE3 ATX10 FAT2 ELOV4 DAPLE SAM9L SPTN2 AT1A3 CAC1G ... 2ABB ATX2 PUM1 ELOV5 DAB1 ATX3 ITPR1 KCNC3 TTBK2 TNR6A CHIP ATX8 ITM2B TBP ATX1 KPCG GRM1 ATN1 FGF14 AFG32 | DI-03793 DOID:1441 D020754 | |
| 3 MYPR PTEN ATP7A | DOID:0050953 | |
| 61 EDN1 NU3M NDUF5 HTRA2 NDUA9 NDUS6 TY3H LRRK2 NDUV1 SYNJ1 ... DJC13 SYUA PRKN PINK1 NDUF6 TM175 VP13C NUBPL NDUS4 TM230 NDUA1 NDUS7 AT132 NDUAC NDUF3 RB39B AAKG2 CIA30 PLPL9 UCHL1 | DI-02134 DOID:14330 D010300 | |
| 13 LITAF DCTN1 NBAS CTDP1 EMC1 TAU TBK1 ANAG PSN1 COQ2 ... SMAD4 DSRAD ATP7A | DI-03867 DOID:4752 D012791 D019578 | |
| 8 DJC13 SYUA PRKN TM175 TM230 UCHL1 GLCM SNCAP | DI-01901 DOID:12217 D020961 | |
| 28 NU2M SORL DNM1L ADA10 NDRG2 DKK1 JIP1 RGPS2 SYUA OGT1 ... PPP5 A4 NU1M PSN2 PRDX1 DREB RBG1L APOE UNC5C TAU GDNF GPC1 ABCA7 PSN1 PRDX2 CAD13 ABI1 OLR1 | DI-03832 DOID:10652 D000544 | |
| 0 | DI-01344 DOID:0050766 D054546 | |
| 17 EXOS3 VPS53 SEN54 TBC23 CLP1 AMPD2 SPCS CHM1A VRK1 SYRM ... PCLO TOE1 SEN34 EXOS9 SEN2 EXOS8 SEN15 | DI-02626 DOID:0060264 C580383 | |
| 3 NPHP1 WWOX ANAG | DOID:9277 D013132 | |
| 4 PRDM8 EPM2A TAU NHLC1 | DOID:3534 D020192 | |
| 1 ACON | DI-03409 DOID:0050883 | |
| 7 TAF1 HD JPH3 PRIO TBP XK SQSTM | DI-01754 DOID:12858 D006816 | |
| 1 NEUS | DI-01567 DOID:0050831 C536841 | |
| 6 ATX2 ATX1 AT2B3 CAC1A ATX7 COQ2 | DOID:14784 D009849 | |
| 0 | DOID:12707 D002527 | |
| 1 S12A6 | DI-00054 DOID:0090003 | |
| 0 | DOID:3688 | |
| 7 NPC1 NPC2 TAU GPC1 ATP7B PSN1 ASM | DI-02937 DOID:11870 D020774 | |
| 0 | DOID:0060491 C563702 | |
| 80 ULK4 PPR3F PTHD1 PHF8 SHAN2 MAGA4 RL10 CRADD MAGL2 TEN1 ... HXA1 RS23 KCND2 SHAN3 IGSF1 DIA1 BACD1 CCD22 MARK1 PPM1D T4S20 SC6A8 MAGE1 MET SETD2 NPRL2 MECP2 SCN2A AGRG2 SCN3A | DOID:0060041 MESH:D000067877 |
| GO ID | Description | Proteins | Score |
|---|---|---|---|
| GO:0016043 | 228 MKS1 DCTN1 ATX10 NDUB3 ADA10 DSRAD NDUA2 RERE FBX7 CFLAR ... IF4G1 DAPLE RB39B T106B PSN2 CACP DKK1 VPS35 TFG SMAD4 TTBK2 TIM14 B9D2 SMN UCHL1 ANGI SETD2 ERBB4 BDNF WDR73 | 26.6766 | |
| GO:0071840 | 232 MKS1 DCTN1 ATX10 NDUB3 ADA10 DSRAD NDUA2 EXOS9 RERE FBX7 ... CFLAR IF4G1 DAPLE RB39B T106B PSN2 CACP DKK1 VPS35 TFG SMAD4 TTBK2 TIM14 FRG1 B9D2 SMN UCHL1 ANGI SETD2 ERBB4 | 26.6766 | |
| GO:0032981 | 29 NDUS2 NU1M NDUB3 NDUS3 NDUF4 NDUA2 NDUAA NDUV2 NDUB9 NDUF2 ... NDUA9 NU2M NDUS4 NDUA1 NDUS8 NU3M NDUS1 CIA30 NDUAC FXRD1 NDUF3 NUBPL NDUS7 NDUS6 NDUBB NDUAB NDUF6 NDUV1 NDUF5 | 26.0508 | |
| GO:0010257 | 29 NDUS2 NU1M NDUB3 NDUS3 NDUF4 NDUA2 NDUAA NDUV2 NDUB9 NDUF2 ... NDUA9 NU2M NDUS4 NDUA1 NDUS8 NU3M NDUS1 CIA30 NDUAC FXRD1 NDUF3 NUBPL NDUS7 NDUS6 NDUBB NDUAB NDUF6 NDUV1 NDUF5 | 26.0508 | |
| GO:0033108 | 31 NDUS2 NU1M NDUB3 NDUS3 NDUF4 NDUA2 NDUAA NDUV2 NDUB9 NDUF2 ... NDUA9 NU2M NDUS4 NDUA1 NDUS8 NU3M NDUS1 CIA30 NDUAC SURF1 SYAM FXRD1 NDUF3 NUBPL NDUS7 NDUS6 NDUBB NDUAB NDUF6 NDUV1 | 24.2953 | |
| GO:0007005 | 55 NDUS2 NDUB3 DNM1L TAU NDUA2 FBX7 NDUV2 IF4G1 PINK1 NDUF2 ... NDUA9 VPS35 CHC10 TIM14 NDUA1 ERBB4 NDUS1 NDUAC SYAM NDUF3 NUBPL NDUS7 NDUS6 LRRK2 OMA1 NU1M NDUS3 NDUF4 NDUAA SL9A1 | 24.0882 | |
| GO:0006996 | 155 MKS1 DCTN1 NDUS2 ATX10 NDUB3 DNM1L ARMC9 TAU TBCE NDUA2 ... RERE FBX7 CFLAR IF4G1 PINK1 NDUF2 CACP VPS35 TFG TTBK2 TIM14 NDUA1 B9D2 ANGI SETD2 HDAC4 ERBB4 WDR73 SYNE1 NDUS1 | 21.5254 | |
| GO:0006120 | 23 NDUS8 NDUS2 NU1M NU3M COQ9 NDUB3 NDUS1 CIA30 NDUAC NDUS3 ... NDUA2 NDUAA NDUS7 NDUV2 NDUS6 NDUB9 NDUBB NDUAB NDUA9 NDUV1 NU2M NDUS4 NDUA1 | 21.0357 | |
| GO:0007399 | 129 MKS1 DCTN1 VLDLR ATX10 DNM1L ADA10 TAU SCN2A TYDP2 GTR1 ... RERE FBX7 CFLAR IF4G1 ZSWM6 T106B NLGNX DKK1 VPS35 MBP SMAD4 TTBK2 BC11B SMN UCHL1 SETD2 HDAC4 MYP0 ERBB4 BDNF | 20.4916 | |
| GO:0022607 | 127 MKS1 ABCA7 DCTN1 NDUS2 ATX10 NDUB3 DNM1L ARMC9 DSRAD TAU ... NDUA2 GTR1 CFLAR DAPLE NDUF2 NLGNX VPS35 TFG SMAD4 TTBK2 NDUA1 B9D2 SMN ANGI ERBB4 BDNF NDUS1 ANK3 NDUAC TF2H2 | 18.9278 | |
| GO:0044085 | 132 MKS1 ABCA7 DCTN1 NDUS2 ATX10 NDUB3 DNM1L ARMC9 DSRAD TAU ... NDUA2 EXOS9 GTR1 CFLAR DAPLE NDUF2 NLGNX VPS35 TFG SMAD4 TTBK2 FRG1 NDUA1 B9D2 SMN ANGI ERBB4 BDNF NDUS1 ANK3 | 18.4841 | |
| GO:0022904 | 27 NDUS2 NU1M COQ9 NDUB3 NDUS3 NDUA2 NDUAA NDUV2 PINK1 NDUB9 ... NDUF2 MECP2 NDUA9 NU2M NDUS4 NDUA1 NDUS8 NU3M NDUS1 CIA30 NDUAC SYUA NDUS7 NDUS6 NDUBB NDUAB NDUV1 | 17.7129 | |
| GO:0042775 | 25 NDUS2 NU1M COQ9 NDUB3 NDUS3 NDUA2 NDUAA NDUV2 NDUB9 MECP2 ... NDUA9 NU2M NDUS4 NDUA1 NDUS8 NU3M NDUS1 CIA30 NDUAC SYUA NDUS7 NDUS6 NDUBB NDUAB NDUV1 | 17.7129 | |
| GO:0042773 | 25 NDUS2 NU1M COQ9 NDUB3 NDUS3 NDUA2 NDUAA NDUV2 NDUB9 MECP2 ... NDUA9 NU2M NDUS4 NDUA1 NDUS8 NU3M NDUS1 CIA30 NDUAC SYUA NDUS7 NDUS6 NDUBB NDUAB NDUV1 | 17.5991 | |
| GO:0007610 | 57 ABD12 ABCA7 DCTN1 KPCG VLDLR ATX3 TAU ATX1 SYGP1 SCN2A ... IF4G1 APOE NLGNX GGYF2 DKK1 SPTCS NPC1 UCHL1 CNTP2 ADNP PLPL9 FIG4 HD SHAN3 A4 GRM1 PSN1 SHAN2 LRRK2 SPTN2 | 17.5478 | |
| GO:0045333 | 31 NDUS2 NU1M COQ9 NDUB3 NDUS3 ODP2 NDUA2 NDUAA NDUV2 PINK1 ... NDUB9 NDUF2 MECP2 NDUA9 PANK2 NU2M NDUS4 NDUA1 NDUS8 NU3M NDUS1 CIA30 NDUAC SURF1 SYUA NDUS7 NDUS6 ACON NDUBB NDUAB | 16.9542 | |
| GO:0006119 | 27 NDUS2 NU1M COQ9 NDUB3 NDUS3 NDUA2 NDUAA NDUV2 NDUB9 MECP2 ... NDUA9 NU2M CHC10 NDUS4 NDUA1 NDUS8 NU3M NDUS1 CIA30 NDUAC SURF1 SYUA NDUS7 NDUS6 NDUBB NDUAB NDUV1 | 16.9010 | |
| GO:0015980 | 33 NDUS2 AAKG2 NU1M COQ9 NDUB3 NDUS3 ODP2 NDUA2 NDUAA NDUV2 ... PINK1 NDUB9 NDUF2 MECP2 NDUA9 PANK2 NU2M NDUS4 NDUA1 NDUS8 NU3M NDUS1 CIA30 NDUAC SURF1 SYUA NHLC1 NDUS7 NDUS6 ACON | 14.2449 | |
| GO:0048731 | 176 MKS1 DCTN1 ASAH1 VLDLR ATX10 DNM1L ADA10 DSRAD TAU SCN2A ... TYDP2 GTR1 RERE FBX7 CFLAR IF4G1 ZSWM6 T106B NLGNX DKK1 VPS35 MBP SMAD4 TTBK2 TIM14 FRG1 S12A6 BC11B SMN UCHL1 | 14.1684 | |
| GO:0048699 | 86 MKS1 VLDLR ATX10 DNM1L ADA10 TAU AFG32 SYGP1 TYDP2 RERE ... TBC23 FBX7 CFLAR IF4G1 ZSWM6 T106B APOE IF140 NLGNX GGYF2 DKK1 SMAD4 SPTCS NOTC3 BC11B UCHL1 ERBB4 BDNF ANK3 ABI1 | 13.3573 | |
| GO:0022008 | 88 MKS1 VLDLR ATX10 DNM1L ADA10 TAU AFG32 SYGP1 TYDP2 RERE ... TBC23 FBX7 CFLAR IF4G1 ZSWM6 T106B APOE IF140 NLGNX GGYF2 DKK1 SMAD4 SPTCS NOTC3 BC11B UCHL1 ERBB4 BDNF ANK3 ABI1 | 12.6630 | |
| GO:0022900 | 28 NDUS2 NU1M COQ9 NDUB3 NDUS3 NDUA2 NDUAA NDUV2 PINK1 NDUB9 ... NDUF2 MECP2 NDUA9 NU2M NDUS4 NDUA1 NDUS8 NU3M NDUS1 CIA30 NDUAC SURF1 SYUA NDUS7 NDUS6 NDUBB NDUAB NDUV1 | 12.4837 | |
| GO:0030182 | 63 MKS1 VLDLR ATX10 TAU AFG32 SYGP1 TYDP2 RERE TBC23 ZSWM6 ... T106B APOE IF140 NLGNX GGYF2 SMAD4 SPTCS NOTC3 BC11B UCHL1 ERBB4 BDNF ANK3 ABI1 CNTP2 HME2 GPC1 CI072 FIG4 SHAN3 | 12.1881 | |
| GO:0009987 | 379 MKS1 COQ2 DCTN1 ATX10 NDUB3 ADA10 DSRAD GRB14 S52A3 SCN2A ... NDUA2 TYDP2 EXOS9 PAR3L RERE DEPD5 FBX7 CFLAR IF4G1 AGRG2 DAPLE RB39B ZSWM6 T106B COQ7 CASPA RPC2 PSN2 CACP DKK1 | 12.1103 | |
| GO:0046034 | 29 NDUS2 AAKG2 NU1M COQ9 NDUB3 NDUS3 NDUA2 NDUAA NDUV2 NDUB9 ... MECP2 NDUA9 TERA NU2M CHC10 NDUS4 NDUA1 NDUS8 NU3M NDUS1 CIA30 NDUAC SURF1 SYUA NDUS7 NDUS6 NDUBB NDUAB NDUV1 | 12.0431 | |
| GO:0050808 | 32 SHAN2 LRRK2 SPTN2 DCTN1 ADA10 TAU AFG32 SYGP1 NFH RB39B ... ALS2 CTND2 APOE MECP2 NLGNX PCLO DKK1 VPS35 CHC10 ERBB4 BDNF ANK3 PROF1 GDNF GRID2 SYUA NLGN3 PTEN SHAN3 A4 | 11.6340 | |
| GO:0051128 | 112 SYT9 ABCA7 DCTN1 VLDLR DNM1L ADA10 TAU EXOS9 FBX7 CFLAR ... IF4G1 PINK1 T106B ROA1 DNJB2 DKK1 VPS35 SMAD4 TTBK2 HDAC4 BDNF FHL1 TF2H2 ADNP XRCC1 PLPL9 FIG4 HD SNCAP TRAK2 | 11.3050 | |
| GO:0065003 | 81 ABCA7 NDUS2 ATX10 NDUB3 DNM1L DSRAD TAU NDUA2 GTR1 ANDR ... NDUV2 DAPLE SGMR1 NDUF2 APOE NDUA9 TERA TFG SMAD4 NDUA1 SMN ANGI BACD1 NDUS1 NDUAC TF2H2 KHDR1 SYAM CAN3 NDUF3 | 11.2774 | |
| GO:0043933 | 89 ABCA7 NDUS2 ATX10 NDUB3 DNM1L DSRAD TAU NDUA2 GTR1 ANDR ... NDUV2 DAPLE SGMR1 NDUF2 APOE NDUA9 TERA TFG SMAD4 CHC10 NDUA1 SMN ANGI SETD2 BACD1 NDUS1 NDUAC TF2H2 KHDR1 SYAM | 10.7949 | |
| GO:0048666 | 53 MKS1 VLDLR ATX10 TAU AFG32 SYGP1 TYDP2 RERE TBC23 T106B ... APOE IF140 SMAD4 SPTCS BC11B UCHL1 BDNF ANK3 ABI1 CNTP2 HME2 GPC1 CI072 FIG4 SHAN3 TRAK2 A4 PSN1 LRRK2 SPTN2 | 10.7248 | |
| GO:0034622 | 51 NDUS2 NDUB3 DNM1L DSRAD TAU NDUA2 NDUV2 NDUF2 NDUA9 SMAD4 ... NDUA1 SMN ANGI NDUS1 NDUAC TF2H2 SYAM NDUF3 NUBPL NDUS7 NDUS6 CI072 NU1M NDUS3 NDUF4 NDUAA POGZ ATX2 NDUB9 SETX | 10.5539 | |
| GO:0007275 | 181 MKS1 DCTN1 ASAH1 VLDLR ATX10 DNM1L ADA10 DSRAD TAU SCN2A ... NDUA2 TYDP2 GTR1 RERE FBX7 CFLAR IF4G1 ZSWM6 T106B NLGNX DKK1 VPS35 MBP SMAD4 TTBK2 TIM14 FRG1 S12A6 BC11B SMN | 10.2662 | |
| GO:0007626 | 26 LRRK2 ABD12 ALS2 FEZF2 APOE MECP2 ATP7A GGYF2 PRKN SPTCS ... SODC NPC1 PUM1 UCHL1 GDNF HTRA2 DAB1 ANAG SYUA FIG4 PTEN KCND2 PARK7 TY3H A4 GRM1 | 9.9148 | |
| GO:0042391 | 36 CACB4 FGF14 LRRK2 EDN1 KCNA1 TAU CAC1G CAC1C CAV3 SL9A1 ... CAC1D PINK1 MECP2 NLGNX GLCM PANK2 TERA PRKN CHC10 SODC FHL1 NDUS1 ANK3 AT1A3 GRID2 SYUA CAC1A NLGN3 PTEN SHAN3 | 9.8218 | |
| GO:0051641 | 100 MKS1 SYT9 ABCA7 DCTN1 DNM1L TAU FBX7 PINK1 T106B PSN2 ... CACP STRAB ROA1 VPS35 TFG TTBK2 TIM14 NPC1 B9D2 SMN UCHL1 SYNE1 ANK3 CD24 HD TRAK2 PTPRC DOC2B CEP41 DREB | 9.7515 | |
| GO:0120036 | 62 MKS1 DCTN1 VLDLR ATX10 ARMC9 TAU AFG32 SYGP1 RERE TBC23 ... PIBF1 T106B APOE IF140 SMAD4 TTBK2 SPTCS B9D2 BC11B UCHL1 BDNF ANK3 AT1A3 ABI1 NEK1 CNTP2 GPC1 CI072 SHAN3 TRAK2 | 9.7103 | |
| GO:0032502 | 196 MKS1 DCTN1 ATX10 ADA10 DSRAD SCN2A NDUA2 TYDP2 RERE FBX7 ... CFLAR IF4G1 ZSWM6 T106B DKK1 VPS35 SMAD4 TTBK2 TIM14 FRG1 SMN UCHL1 ANGI SETD2 MYP0 ERBB4 BDNF SYNE1 ANK3 CD24 | 9.6273 | |
| GO:0050804 | 37 SYT9 SHAN2 FGF14 LRRK2 EDN1 KPCG DNM1L TAU SYGP1 CAC1D ... PINK1 APOE MECP2 NLGNX DKK1 PRKN VAMP1 SQSTM JPH3 BACD1 GDNF GRID2 SYUA CAC1A NLGN3 ADNP PLPL9 PTEN SHAN3 SNCAP | 9.6139 | |
| GO:0099177 | 37 SYT9 SHAN2 FGF14 LRRK2 EDN1 KPCG DNM1L TAU SYGP1 CAC1D ... PINK1 APOE MECP2 NLGNX DKK1 PRKN VAMP1 SQSTM JPH3 BACD1 GDNF GRID2 SYUA CAC1A NLGN3 ADNP PLPL9 PTEN SHAN3 SNCAP | 9.5981 | |
| GO:0032989 | 49 VLDLR DNM1L AFG32 ANDR RERE CFLAR T106B DKK1 SMAD4 SPTCS ... BC11B UCHL1 BDNF ANK3 ABI1 CAN3 CNTP2 NUBPL GPC1 NDUS6 IL7RA CI072 FIG4 SHAN3 TRAK2 A4 FLNA LRRK2 SPTN2 SIAH1 | 9.5981 | |
| GO:0007417 | 59 ATN1 DCTN1 VLDLR TAU ATX1 GTR1 RERE TBC23 ZSWM6 NLGNX ... GGYF2 DKK1 MBP TTBK2 NOTC3 BC11B SETD2 ERBB4 CNTP2 HME2 XRCC1 SHAN3 A4 PSN1 FLNA LRRK2 SPTN2 CNTN6 KCNA1 NDUS3 | 9.4991 | |
| GO:0048856 | 187 MKS1 DCTN1 ASAH1 VLDLR ATX10 DNM1L ADA10 DSRAD TAU SCN2A ... NDUA2 TYDP2 GTR1 RERE FBX7 CFLAR IF4G1 ZSWM6 T106B NLGNX DKK1 VPS35 MBP SMAD4 TTBK2 TIM14 FRG1 S12A6 BC11B SMN | 9.4497 | |
| GO:0048468 | 78 MKS1 VLDLR ATX10 TAU AFG32 SYGP1 TYDP2 ANDR RERE TBC23 ... CFLAR T106B APOE IF140 DKK1 SMAD4 SPTCS BC11B UCHL1 ANGI SETD2 HDAC4 ERBB4 BDNF ANK3 ABI1 CAN3 WT1 CNTP2 HME2 | 9.4287 | |
| GO:0030030 | 62 MKS1 DCTN1 VLDLR ATX10 ARMC9 TAU AFG32 SYGP1 RERE TBC23 ... PIBF1 T106B APOE IF140 SMAD4 TTBK2 SPTCS B9D2 BC11B UCHL1 BDNF ANK3 AT1A3 ABI1 NEK1 CNTP2 GPC1 CI072 SHAN3 TRAK2 | 9.0901 | |
| GO:0051129 | 46 LRRK2 OMA1 ABCA7 SPTN2 DNM1L TAU PHF8 SYGP1 ANDR CAV3 ... CFLAR ATX2 UBQL2 PINK1 MET ATG5 APOE GLCM ROA1 SORL DNJB2 DKK1 VPS35 SMAD4 PRKN TTBK2 DNMT1 PROF1 HTRA2 DAB1 | 8.7521 | |
| GO:0050890 | 30 SHAN2 ABCA7 KPCG VLDLR TAU ATX1 SYGP1 SCN2A CHM2B APOE ... MECP2 NLGNX HXA1 DKK1 PRKN JPH3 SYNJ1 CNTP2 NLGN3 ADNP PLPL9 PTHD1 HD PTEN SHAN3 TY3H NEP A4 PRIO PSN1 | 8.7360 | |
| GO:0031329 | 52 ITPR1 KPCG DNM1L ATX3 TAU EXOS9 FBX7 IF4G1 RB39B PINK1 ... APOE GGYF2 DNJB2 TERA VPS35 NPC1 OGT1 UCHL1 AT132 CI072 HD PSN1 LRRK2 AAKG2 TBK1 CCD22 OPTN CAV3 UBQL2 MET | 8.7360 | |
| GO:901214 | 31 LRRK2 KPCG TAU SYGP1 TBK1 FBX7 IF4G1 SGMR1 PINK1 APOE ... MECP2 GLCM CASP8 SORL DKK1 VPS35 PRKN SODC HDAC4 GDNF HTRA2 AT132 GRID2 SYUA HME2 ADNP PARK7 BIRC1 PPP5 PRIO | 8.7313 | |
| GO:0032990 | 37 LRRK2 SPTN2 VLDLR DNM1L SIAH1 AFG32 TOP2B RERE NFH ALS2 ... FEZF2 CTND2 T106B ATP7A PANK2 SMAD4 SPTCS BC11B UCHL1 RAPH1 BDNF ANK3 GDNF ABI1 DAB1 UNC5C CNTP2 NUBPL NLGN3 GPC1 | 8.7109 | |
| GO:0098916 | 31 KIF5A SYT9 LRRK2 KPCG KCNA1 ATX3 CAC1G CAC1D ALS2 APOE ... MECP2 PCLO MBP PRKN SPTCS VAMP1 MYP0 SC5A7 SYNJ1 GRID2 SYUA NLGN3 PTEN KCND2 PARK7 DOC2B MYPR TY3H EAA1 GRM1 | 8.6840 | |
| GO:0007268 | 31 KIF5A SYT9 LRRK2 KPCG KCNA1 ATX3 CAC1G CAC1D ALS2 APOE ... MECP2 PCLO MBP PRKN SPTCS VAMP1 MYP0 SC5A7 SYNJ1 GRID2 SYUA NLGN3 PTEN KCND2 PARK7 DOC2B MYPR TY3H EAA1 GRM1 | 8.6840 | |
| GO:0031175 | 43 MKS1 LRRK2 SPTN2 VLDLR ATX10 LAMA1 TAU SIAH1 AFG32 SYGP1 ... TOP2B RERE TBC23 NFH ALS2 FEZF2 CTND2 T106B APOE MECP2 ATP7A SMAD4 SPTCS SODC BC11B UCHL1 RAPH1 BDNF ANK3 GDNF | 8.6577 | |
| GO:0016310 | 68 NDUS2 KPCG NDUB3 ADA10 SYGP1 TPK1 NDUA2 NDUV2 PIBF1 PINK1 ... NPRL2 NDUA9 SCYL1 MBP CHC10 TTBK2 NDUA1 ERBB4 NDUS1 NDUAC TF2H2 PPM1D ABI1 NEK1 AT132 NDUS7 NDUS6 SHAN3 BCKD A4 | 8.6516 | |
| GO:0099537 | 31 KIF5A SYT9 LRRK2 KPCG KCNA1 ATX3 CAC1G CAC1D ALS2 APOE ... MECP2 PCLO MBP PRKN SPTCS VAMP1 MYP0 SC5A7 SYNJ1 GRID2 SYUA NLGN3 PTEN KCND2 PARK7 DOC2B MYPR TY3H EAA1 GRM1 | 8.2452 | |
| GO:0007611 | 27 SHAN2 ABCA7 KPCG VLDLR TAU ATX1 SYGP1 SCN2A APOE MECP2 ... NLGNX DKK1 PRKN JPH3 SYNJ1 CNTP2 NLGN3 ADNP PLPL9 HD PTEN SHAN3 TY3H NEP A4 PRIO PSN1 | 8.1885 | |
| GO:0099536 | 31 KIF5A SYT9 LRRK2 KPCG KCNA1 ATX3 CAC1G CAC1D ALS2 APOE ... MECP2 PCLO MBP PRKN SPTCS VAMP1 MYP0 SC5A7 SYNJ1 GRID2 SYUA NLGN3 PTEN KCND2 PARK7 DOC2B MYPR TY3H EAA1 GRM1 | 7.9603 | |
| GO:0044087 | 54 DCTN1 DNM1L TAU IF4G1 PINK1 APOE IF140 DNJB2 TERA DKK1 ... VPS35 SMAD4 HDAC4 BDNF TF2H2 AT132 ADNP PLPL9 CI072 HD SHAN3 SNCAP TEN1 A4 FLNA LRRK2 SPTN2 EDN1 CHM2B CAV3 | 7.9603 | |
| GO:0030534 | 20 SHAN2 UCHL1 ABD12 SPTN2 GDNF HTRA2 DAB1 SYUA CNTP2 NLGN3 ... PTEN SHAN3 PARK7 MECP2 NLGNX GGYF2 A4 PRKN NPC1 PUM1 | 7.9131 | |
| GO:0009894 | 56 ITPR1 KPCG DNM1L ATX3 TAU EXOS9 FBX7 IF4G1 RB39B PINK1 ... APOE GGYF2 DNJB2 TERA VPS35 NPC1 OGT1 UCHL1 HDAC4 AT132 CI072 HD PSN1 FLNA LRRK2 BSCL2 AAKG2 TBK1 CCD22 OPTN | 7.9101 | |
| GO:0032501 | 222 MKS1 DCTN1 ATX10 ADA10 DSRAD S52A3 SCN2A NDUA2 TYDP2 RERE ... FBX7 CFLAR IF4G1 AGRG2 ZSWM6 T106B DKK1 VPS35 SMAD4 TTBK2 TIM14 FRG1 SMN UCHL1 ANGI SETD2 MYP0 ERBB4 BDNF SYNE1 | 7.8993 | |
| GO:0007420 | 47 LRRK2 SPTN2 KCNA1 NDUS3 NDRG2 PHF8 ATX1 TOP2B RORA GTR1 ... RERE TBC23 ZSWM6 FEZF2 MECP2 NLGNX ATP7A DKK1 MBP TTBK2 CE120 NDUS4 NOTC3 BC11B SETD2 ERBB4 CLP1 HTRA2 DAB1 UNC5C | 7.8839 | |
| GO:903146 | 12 VP13C PINK1 HD DNM1L PARK7 HTRA2 GLCM VP13D AT132 OPTN ... PRKN FBX7 | 7.8524 | |
| GO:0051130 | 64 SYT9 ABCA7 DCTN1 VLDLR DNM1L TAU ANDR FBX7 CFLAR IF4G1 ... PINK1 T106B APOE ROA1 TERA VPS35 SMAD4 CHC10 OGT1 HDAC4 BDNF TF2H2 ADNP PLPL9 FIG4 HD SHAN3 DOC2B DREB TEN1 | 7.8396 | |
| GO:0051179 | 183 MKS1 CACB4 SYT9 ABCA7 DCTN1 ASAH1 VLDLR DNM1L ADA10 GRB14 ... TAU S52A3 SCN2A GTR1 RERE FBX7 RB39B PINK1 SCN3A T106B PSN2 SCYL1 CACP STRAB ROA1 VPS35 TFG TTBK2 TIM14 S12A6 | 7.7509 | |
| GO:0048667 | 32 SPTN2 VLDLR SIAH1 AFG32 TOP2B RERE NFH ALS2 FEZF2 CTND2 ... T106B SMAD4 SPTCS SODC BC11B UCHL1 RAPH1 BDNF ANK3 GDNF ABI1 DAB1 UNC5C NLGN3 GPC1 AUTS2 CI072 PTEN SHAN3 TRAK2 | 7.7319 | |
| GO:0006091 | 34 NDUS2 AAKG2 NU1M COQ9 NDUB3 NDUS3 ODP2 NDUA2 NDUAA NDUV2 ... PINK1 NDUB9 NDUF2 MECP2 NDUA9 PANK2 NU2M CHC10 NDUS4 NDUA1 NDUS8 NU3M NDUS1 CIA30 NDUAC SURF1 SYUA NHLC1 NDUS7 NDUS6 | 7.6084 | |
| GO:0006793 | 93 ABD12 NDUS2 KPCG NDUB3 ADA10 ODP2 SYGP1 TPK1 NDUA2 NDUV2 ... PIBF1 PINK1 NPRL2 PURA1 NDUA9 SCYL1 TERA MBP CHC10 TTBK2 NDUA1 ERBB4 ELOV4 NDUS1 NDUAC TF2H2 PPM1D ABI1 NEK1 AT132 | 7.5382 | |
| GO:0060322 | 48 MKS1 LRRK2 SPTN2 KCNA1 NDUS3 NDRG2 PHF8 ATX1 TOP2B RORA ... GTR1 RERE TBC23 ZSWM6 FEZF2 MECP2 NLGNX ATP7A DKK1 MBP TTBK2 CE120 NDUS4 NOTC3 BC11B SETD2 ERBB4 CLP1 HTRA2 DAB1 | 7.5370 | |
| GO:0010941 | 79 ASAH1 KPCG DNM1L ADA10 DSRAD TAU SYGP1 ANDR FBX7 CFLAR ... IF4G1 SGMR1 PINK1 APOE CASPA PSN2 STRAB TERA DKK1 VPS35 SMAD4 CHC10 NPC1 BC11B HDAC4 MYP0 BDNF WDR73 DIA1 WWOX | 7.5370 | |
| GO:0008152 | 253 COQ2 NDUB3 ADA10 DSRAD S52A3 NDUA2 TYDP2 EXOS9 FBX7 CFLAR ... IF4G1 RB39B COQ7 CASPA RPC2 PSN2 CACP SMAD4 TTBK2 FRG1 SEN15 SMN UCHL1 ANGI SETD2 ERBB4 NDUS1 NDUAC CD24 UBA5 | 7.5349 | |
| GO:0065008 | 141 MKS1 CACB4 SYT9 ABCA7 DCTN1 DNM1L ADA10 DSRAD TAU EXOS9 ... GTR1 FBX7 IF4G1 DAPLE PINK1 NDUF2 NLGNX ROA1 DNJB2 DKK1 VPS35 MBP SMAD4 NPC1 ANGI ERBB4 BDNF FHL1 SYNE1 NDUS1 | 7.5217 | |
| GO:0120035 | 43 LRRK2 VLDLR DNM1L ADA10 TAU SYGP1 MARK1 FBX7 CFLAR FEZF2 ... ATG5 T106B APOE SETX IF140 ATP7A DKK1 VPS35 PRKN CE120 HDAC4 BDNF ULK4 PROF1 DAB1 XK GRID2 TRPV4 NLGN3 ADNP | 7.5217 | |
| GO:0006796 | 92 ABD12 NDUS2 KPCG NDUB3 ADA10 ODP2 SYGP1 TPK1 NDUA2 NDUV2 ... PIBF1 PINK1 NPRL2 PURA1 NDUA9 SCYL1 TERA MBP CHC10 TTBK2 NDUA1 ERBB4 ELOV4 NDUS1 NDUAC TF2H2 PPM1D ABI1 NEK1 AT132 | 7.4951 | |
| GO:0000904 | 36 SPTN2 VLDLR SIAH1 AFG32 TOP2B ANDR RERE NFH ALS2 FEZF2 ... MET CTND2 T106B DKK1 SMAD4 SPTCS SODC BC11B UCHL1 RAPH1 BDNF ANK3 GDNF ABI1 DAB1 UNC5C NLGN3 GPC1 AUTS2 CI072 | 7.4466 | |
| GO:0051640 | 39 MKS1 KIF5A SYT9 TM230 LRRK2 DCTN1 KIF1C DNM1L TAU CHM2B ... CAV3 TBC23 MARK1 PIBF1 T106B BRAT1 PSN2 NPHP1 PCLO TFG TTBK2 CE120 SPTCS VAMP1 B9D2 UCHL1 BICD2 DAB1 SYNJ1 SYUA | 7.4384 | |
| GO:0032268 | 103 ABCA7 VLDLR DNM1L DSRAD TAU FBX7 CFLAR IF4G1 DAPLE PINK1 ... STRAB DNJB2 DKK1 VPS35 MBP SMAD4 UCHL1 ANGI HDAC4 ERBB4 BDNF CD24 ABI1 TNR6A NHLC1 ADNP XRCC1 PLPL9 HD PTPRC | 7.3998 | |
| GO:0031399 | 81 ABCA7 KPCG VLDLR DNM1L DSRAD TAU SYGP1 ANDR FBX7 CFLAR ... IF4G1 DAPLE PIBF1 PINK1 APOE BRAT1 STRAB DNJB2 TERA DKK1 SMAD4 OGT1 UCHL1 ANGI HDAC4 ERBB4 BDNF CD24 ABI1 CAN3 | 7.3784 | |
| GO:0033043 | 63 SYT9 DCTN1 DNM1L TAU FBX7 PINK1 IF140 ROA1 VPS35 SMAD4 ... CHC10 TTBK2 OGT1 TF2H2 AT132 XRCC1 PLPL9 CI072 HD SHAN3 DOC2B TEN1 FLNA LRRK2 OMA1 SPTN2 EDN1 PHF8 CHM2B OPTN | 7.3784 | |
| GO:0031344 | 43 LRRK2 VLDLR DNM1L ADA10 TAU SYGP1 MARK1 FBX7 CFLAR FEZF2 ... ATG5 T106B APOE SETX IF140 ATP7A DKK1 VPS35 PRKN CE120 HDAC4 BDNF ULK4 PROF1 DAB1 XK GRID2 TRPV4 NLGN3 ADNP | 7.3653 | |
| GO:0060548 | 56 KPCG DSRAD SYGP1 ANDR FBX7 CFLAR IF4G1 PINK1 APOE STRAB ... DKK1 VPS35 SMAD4 NPC1 BC11B MYP0 BDNF WDR73 DIA1 AT132 CAN3 WT1 HME2 ADNP IL7RA HD RL10 PSN1 FLNA LRRK2 | 7.3268 | |
| GO:0051049 | 83 CACB4 SYT9 ABCA7 ITPR1 KPCG DNM1L SCN2A GTR1 CLCN2 PINK1 ... SCN8A NDUF2 SCN3A APOE PSN2 DKK1 VPS35 MBP SMAD4 CHC10 ANGI SETD2 FHL1 ANK3 KHDR1 AT132 CAN3 CAC1A PLPL9 AUXI | 7.3237 | |
| GO:0048812 | 33 LRRK2 SPTN2 VLDLR SIAH1 AFG32 TOP2B RERE NFH ALS2 FEZF2 ... CTND2 T106B ATP7A SMAD4 SPTCS BC11B UCHL1 RAPH1 BDNF ANK3 GDNF ABI1 DAB1 UNC5C CNTP2 NLGN3 GPC1 AUTS2 CI072 PTEN | 7.2976 | |
| GO:901215 | 23 LRRK2 KPCG GDNF HTRA2 SYGP1 AT132 SYUA HME2 FBX7 ADNP ... IF4G1 PINK1 APOE PARK7 MECP2 GLCM BIRC1 PPP5 SORL VPS35 PRKN PSN1 SODC | 7.2929 | |
| GO:0010506 | 29 LRRK2 ITPR1 AAKG2 DNM1L TAU TBK1 OPTN FBX7 IF4G1 RB39B ... UBQL2 PINK1 MET ATG5 GLCM VPS35 PRKN NPC1 UCHL1 HTRA2 VP13D AT132 SYUA UBQL4 VP13C CI072 HD PARK7 RUBIC | 7.2840 | |
| GO:0034765 | 35 CACB4 FGF14 KCNA1 CAC1G SCN2A CAC1C CAV3 CLCN2 SL9A1 CAC1D ... PINK1 SCN8A SCN3A ATG5 ATP7A PSN2 CHC10 FHL1 JPH3 ANK3 CAN3 SYUA CAC1A NLGN3 PLPL9 HD PTEN SHAN3 KCND2 PARK7 | 7.2434 | |
| GO:0120039 | 33 LRRK2 SPTN2 VLDLR SIAH1 AFG32 TOP2B RERE NFH ALS2 FEZF2 ... CTND2 T106B ATP7A SMAD4 SPTCS BC11B UCHL1 RAPH1 BDNF ANK3 GDNF ABI1 DAB1 UNC5C CNTP2 NLGN3 GPC1 AUTS2 CI072 PTEN | 7.2067 | |
| GO:0010821 | 21 SQSTM LRRK2 OMA1 DNM1L TAU HTRA2 VP13D AT132 OPTN FBX7 ... PLPL9 VP13C PINK1 HD HUWE1 PARK7 GLCM CASP8 VPS35 PRKN CHC10 | 7.1312 | |
| GO:0048858 | 33 LRRK2 SPTN2 VLDLR SIAH1 AFG32 TOP2B RERE NFH ALS2 FEZF2 ... CTND2 T106B ATP7A SMAD4 SPTCS BC11B UCHL1 RAPH1 BDNF ANK3 GDNF ABI1 DAB1 UNC5C CNTP2 NLGN3 GPC1 AUTS2 CI072 PTEN | 7.1066 | |
| GO:0055065 | 37 FRIL ITPR1 EDN1 KCNA1 AFG32 CAC1C VAPB CCD22 CAV3 SL9A1 ... CAC1D APOE ATP7A SMAD4 PRKN SODC JPH3 ANK3 AT1A3 CD24 XK AT132 CAN3 TRPV4 SYUA CAC1A SELT PLPL9 HD TRPM7 | 7.0128 | |
| GO:0034762 | 38 CACB4 FGF14 EDN1 AAKG2 KCNA1 CAC1G SCN2A CAC1C GTR1 CAV3 ... CLCN2 SL9A1 CAC1D PINK1 SCN8A SCN3A ATG5 ATP7A PSN2 CHC10 FHL1 JPH3 ANK3 CAN3 SYUA CAC1A NLGN3 PLPL9 HD PTEN | 6.9770 | |
| GO:0000902 | 40 LRRK2 SPTN2 VLDLR SIAH1 AFG32 TOP2B ANDR RERE NFH ALS2 ... FEZF2 MET CTND2 T106B ATP7A DKK1 SMAD4 SPTCS SODC BC11B UCHL1 RAPH1 BDNF ANK3 GDNF ABI1 DAB1 UNC5C CNTP2 NLGN3 | 6.9770 | |
| GO:903362 | 24 OGT1 LRRK2 KPCG ATX3 AMER1 AT132 CCD22 CAV3 UBQL4 CHIP ... UBQL2 PINK1 PTEN APOE PARK7 FHIT GLCM SUFU DNJB2 TERA VPS35 PRKN TAF1 PSN1 | 6.9292 | |
| GO:0006979 | 31 LRRK2 NDUS2 EDN1 NU1M APTX TAU CFLAR SGMR1 PINK1 ALS2 ... PNKP APOE SETX ATP7A PRKN SODC NDUS8 NU3M PRDX2 NDUAC HTRA2 PRDX1 AT132 SYUA XRCC1 PARK7 PPP5 A4 ARGI1 PRIO | 6.8552 | |
| GO:0010648 | 66 APCL ITPR1 DSRAD GRB14 SYGP1 ANDR DEPD5 CFLAR PIBF1 PINK1 ... NDUF2 APOE NPRL2 NLGNX STRAB DKK1 SMAD4 NOTC3 UCHL1 BDNF BACD1 TF2H2 WWOX ADNP PLPL9 GPC1 HD FCRL3 PTPRC PSN1 | 6.8291 | |
| GO:0043269 | 42 CACB4 FGF14 ABCA7 EDN1 KCNA1 CAC1G SCN2A CAC1C CAV3 CLCN2 ... SL9A1 CAC1D PINK1 SCN8A SCN3A ATG5 APOE ATP7A PSN2 PRKN CHC10 FHL1 JPH3 ANK3 GDNF CAN3 SYUA CAC1A NLGN3 PLPL9 | 6.8291 | |
| GO:0055080 | 39 LRRK2 FRIL ITPR1 EDN1 KCNA1 AFG32 CAC1C VAPB TM175 CCD22 ... CAV3 SL9A1 CAC1D APOE ATP7A SMAD4 PRKN SODC JPH3 ANK3 AT1A3 CD24 XK AT132 CAN3 TRPV4 SYUA CAC1A SELT PLPL9 | 6.8077 | |
| GO:0023057 | 66 APCL ITPR1 DSRAD GRB14 SYGP1 ANDR DEPD5 CFLAR PIBF1 PINK1 ... NDUF2 APOE NPRL2 NLGNX STRAB DKK1 SMAD4 NOTC3 UCHL1 BDNF BACD1 TF2H2 WWOX ADNP PLPL9 GPC1 HD FCRL3 PTPRC PSN1 | 6.7857 | |
| GO:0006875 | 34 FRIL ITPR1 EDN1 AFG32 CAC1C VAPB CCD22 CAV3 SL9A1 CAC1D ... APOE ATP7A SMAD4 SODC JPH3 AT1A3 CD24 XK AT132 CAN3 TRPV4 SYUA CAC1A SELT PLPL9 HD TRPM7 ATP7B PTPRC AT2B3 | 6.7857 | |
| GO:0010646 | 135 MKS1 SYT9 ABCA7 DNM1L DSRAD GRB14 TAU GTR1 DEPD5 CFLAR ... PINK1 NDUF2 NLGNX CASPA STRAB DKK1 VPS35 TFG SMAD4 UCHL1 ERBB4 BDNF ANK3 TF2H2 CD24 UBA5 CAC1A ADNP PLPL9 IL7RA | 6.7410 | |
| GO:0023051 | 136 MKS1 SYT9 ABCA7 DNM1L DSRAD GRB14 TAU GTR1 DEPD5 CFLAR ... PINK1 NDUF2 NLGNX CASPA STRAB DKK1 VPS35 TFG SMAD4 UCHL1 ERBB4 BDNF AT1A3 TF2H2 CD24 UBA5 CAC1A ADNP PLPL9 IL7RA | 6.7037 | |
| GO:0030003 | 36 LRRK2 FRIL ITPR1 EDN1 AFG32 CAC1C VAPB TM175 CCD22 CAV3 ... SL9A1 CAC1D APOE ATP7A SMAD4 SODC JPH3 AT1A3 CD24 XK AT132 CAN3 TRPV4 SYUA CAC1A SELT PLPL9 HD TRPM7 ATP7B | 6.6649 | |
| GO:0051246 | 105 ABCA7 VLDLR DNM1L DSRAD TAU FBX7 CFLAR IF4G1 DAPLE PINK1 ... STRAB DNJB2 DKK1 VPS35 MBP SMAD4 UCHL1 ANGI HDAC4 ERBB4 BDNF CD24 ABI1 TNR6A NHLC1 ADNP XRCC1 PLPL9 HD PTPRC | 6.5979 | |
| GO:0044237 | 230 COQ2 NDUB3 ADA10 DSRAD S52A3 NDUA2 TYDP2 EXOS9 FBX7 IF4G1 ... RB39B COQ7 RPC2 PSN2 CACP SMAD4 TTBK2 FRG1 SEN15 SMN UCHL1 ANGI SETD2 ERBB4 NDUS1 NDUAC UBA5 ABI1 NEK1 SYMM | 6.5979 | |
| GO:0098771 | 39 LRRK2 FRIL ITPR1 EDN1 KCNA1 AFG32 CAC1C VAPB TM175 CCD22 ... CAV3 SL9A1 CAC1D APOE ATP7A SMAD4 PRKN SODC JPH3 ANK3 AT1A3 CD24 XK AT132 CAN3 TRPV4 SYUA CAC1A SELT PLPL9 | 6.5819 | |
| GO:0009628 | 59 ABD12 ITPR1 DNM1L DPOG1 ATX3 TAU S52A3 SYGP1 SCN2A GTR1 ... CFLAR PINK1 BRAT1 PURA1 PSN2 TERA SMAD4 S12A6 ANGI HDAC4 ELOV4 TF2H2 CD24 PPM1D CAN3 CNTP2 XRCC1 HD SHAN3 PTPRC | 6.5611 | |
| GO:0007267 | 54 SYT9 APCL KPCG ADA10 ATX3 TAU ANDR DAPLE APOE DKK1 ... VPS35 MBP SPTCS MYP0 SC5A7 CD24 WWOX TNR6A DOC2B GRM1 PSN1 KIF5A FGF14 LRRK2 EDN1 KCNA1 NDRG2 CAC1G CAC1C MARK1 | 6.5242 | |
| GO:0050905 | 16 UCHL1 DCTN1 KCNA1 JPH3 UBA5 GRID2 NKX62 CHD8 PTEN MECP2 ... GGYF2 TPP1 HXA1 EAA1 A4 PRKN | 6.4677 | |
| GO:903599 | 8 PINK1 HD PARK7 GLCM VP13D OPTN PRKN FBX7 | 6.4366 | |
| GO:0060341 | 50 SYT9 ABCA7 KPCG DNM1L ADA10 TAU ANDR PINK1 NDUF2 VPS35 ... TTBK2 SETD2 ERBB4 BDNF ANK3 KHDR1 AT132 CAN3 NHLC1 PLPL9 HD SNCAP DREB TEN1 PSN1 FLNA FGF14 LRRK2 CAC1C DJC13 | 6.4319 | |
| GO:0006873 | 36 LRRK2 FRIL ITPR1 EDN1 AFG32 CAC1C VAPB TM175 CCD22 CAV3 ... SL9A1 CAC1D APOE ATP7A SMAD4 SODC JPH3 AT1A3 CD24 XK AT132 CAN3 TRPV4 SYUA CAC1A SELT PLPL9 HD TRPM7 ATP7B | 6.4035 | |
| GO:0048585 | 73 APCL ITPR1 DSRAD GRB14 SYGP1 ANDR DEPD5 FBX7 CFLAR PIBF1 ... PINK1 NDUF2 APOE NPRL2 NLGNX STRAB DKK1 VPS35 SMAD4 NOTC3 UCHL1 BDNF BACD1 TF2H2 WWOX XRCC1 GPC1 IL7RA HD FCRL3 | 6.3693 | |
| GO:0010638 | 39 SYT9 LRRK2 DCTN1 EDN1 DNM1L TAU OPTN CAV3 FBX7 PINK1 ... MET PNKP HUWE1 MECP2 GLCM CASP8 ROA1 VPS35 SMAD4 PRKN CHC10 CE120 DNMT1 OGT1 PROF1 TF2H2 HTRA2 VP13D SYNJ1 TRPV4 | 6.2589 | |
| GO:0050801 | 41 LRRK2 FRIL ITPR1 EDN1 KCNA1 AFG32 CAC1G CAC1C VAPB TM175 ... CCD22 CAV3 SL9A1 CAC1D APOE ATP7A SMAD4 PRKN SODC FHL1 JPH3 ANK3 AT1A3 CD24 XK AT132 CAN3 TRPV4 SYUA CAC1A | 6.2308 | |
| GO:0019725 | 45 FGGY LRRK2 FRIL DCTN1 ITPR1 EDN1 DPOG1 AFG32 CAC1C VAPB ... CHM2B TM175 CCD22 CAV3 SL9A1 CAC1D ATG5 APOE ATP7A DNJB2 SMAD4 PRKN SODC JPH3 AT1A3 CD24 XK AT132 CAN3 TRPV4 | 6.2096 | |
| GO:0009968 | 61 APCL ITPR1 DSRAD GRB14 SYGP1 ANDR DEPD5 CFLAR PIBF1 PINK1 ... APOE NPRL2 NLGNX STRAB DKK1 SMAD4 NOTC3 UCHL1 BDNF BACD1 TF2H2 WWOX GPC1 HD FCRL3 PTPRC PSN1 LRRK2 NDUS3 SIAH1 | 6.1561 | |
| GO:0010035 | 35 LRRK2 EDN1 FUS KCNA1 APTX TAU CAC1G ANX11 CFLAR SGMR1 ... PINK1 SETX ATP7A CARTF CASP8 ROA1 TERA PRKN SODC NPC1 PRDX2 ANK3 ACTS AT132 CAN3 SYUA ADNP PTEN ATP7B PARK7 | 6.1462 | |
| GO:903050 | 21 OGT1 LRRK2 KPCG ATX3 CCD22 CAV3 UBQL4 CHIP UBQL2 PINK1 ... PTEN APOE PARK7 FHIT GLCM SUFU DNJB2 TERA PRKN TAF1 PSN1 | 6.1439 | |
| GO:0031331 | 28 LRRK2 ATX3 TBK1 CCD22 OPTN CAV3 FBX7 UBQL2 PINK1 ATG5 ... APOE GGYF2 GLCM DNJB2 TERA VPS35 PRKN PUM1 AMER1 VP13D SYUA CHIP CI072 HD PTEN PARK7 TAF1 PSN1 | 6.1176 | |
| GO:0048523 | 155 ABCA7 VLDLR DNM1L ADA10 DSRAD GRB14 TAU TYDP2 RERE DEPD5 ... FBX7 CFLAR IF4G1 PINK1 NDUF2 NLGNX STRAB ROA1 DNJB2 DKK1 VPS35 MBP SMAD4 TTBK2 NPC1 BC11B UCHL1 ANGI HDAC4 MYP0 | 6.0910 | |
| GO:0030154 | 127 MKS1 ASAH1 VLDLR ATX10 DNM1L ADA10 DSRAD TAU TYDP2 RERE ... FBX7 CFLAR IF4G1 ZSWM6 T106B NLGNX DKK1 SMAD4 BC11B UCHL1 ANGI SETD2 HDAC4 ERBB4 BDNF FHL1 SYNE1 ANK3 CD24 ABI1 | 6.0438 | |
| GO:0050803 | 22 LRRK2 DCTN1 BDNF DNM1L ADA10 SYGP1 CHM2B GRID2 SYUA NLGN3 ... ADNP IF4G1 CTTB2 PTEN SHAN3 APOE DREB TERA DKK1 VPS35 A4 PRIO | 6.0294 | |
| GO:0048869 | 129 MKS1 ASAH1 VLDLR ATX10 DNM1L ADA10 DSRAD TAU TYDP2 RERE ... FBX7 CFLAR IF4G1 ZSWM6 T106B NLGNX DKK1 SMAD4 BC11B UCHL1 ANGI SETD2 HDAC4 ERBB4 BDNF FHL1 SYNE1 ANK3 CD24 ABI1 | 6.0252 | |
| GO:0016241 | 19 UCHL1 LRRK2 AAKG2 HTRA2 VP13D TBK1 AT132 OPTN UBQL4 VP13C ... UBQL2 PINK1 CI072 HD GLCM VPS35 PRKN RUBIC NPC1 | 5.9763 | |
| GO:904062 | 26 CACB4 FGF14 KCNA1 CAC1C CAV3 SL9A1 CAC1D PINK1 ATG5 ATP7A ... PSN2 CHC10 FHL1 JPH3 ANK3 CAN3 SYUA NLGN3 PLPL9 HD PTEN SHAN3 PARK7 A4 PRIO FLNA | 5.9621 | |
| GO:0035176 | 11 SHAN2 PTHD1 PTEN SHAN3 MECP2 ATX1 NLGNX TY3H CHD8 CNTP2 ... NLGN3 | 5.9520 | |
| GO:0051703 | 11 SHAN2 PTHD1 PTEN SHAN3 MECP2 ATX1 NLGNX TY3H CHD8 CNTP2 ... NLGN3 | 5.9520 | |
| GO:0033554 | 72 DCTN1 ITPR1 DPOG1 ATX3 TAU S52A3 SCN2A TYDP2 GTR1 DEPD5 ... CFLAR DAPLE SGMR1 PINK1 NPRL2 GGYF2 BRAT1 ROA1 TERA S12A6 SETD2 TF2H2 UBA5 PPM1D NEK1 AT132 CAN3 TNR6A NHLC1 XRCC1 | 5.9513 | |
| GO:0032879 | 104 CACB4 SYT9 ABCA7 DNM1L ADA10 TAU SCN2A GTR1 PINK1 NDUF2 ... SCN3A PSN2 DKK1 VPS35 MBP SMAD4 TTBK2 ANGI SETD2 HDAC4 ERBB4 BDNF FHL1 ANK3 NHLC1 CAC1A PLPL9 HD SNCAP PTPRC | 5.9324 | |
| GO:0008344 | 13 UCHL1 ABD12 GDNF HTRA2 DAB1 SYUA PARK7 MECP2 GGYF2 A4 ... PRKN NPC1 PUM1 | 5.9100 | |
| GO:0051649 | 70 SYT9 DCTN1 ITPR1 DNM1L TAU ATX1 TBC23 FBX7 PIBF1 APOE ... IF140 CACP STRAB ROA1 TERA VPS35 TFG TIM14 SPTCS NPC1 SMN NPC2 UCHL1 ANK3 SC5A7 CD24 AUXI HD TRAK2 PTPRC | 5.8868 | |
| GO:0042325 | 68 ABCA7 VLDLR DSRAD TAU SYGP1 ANDR FBX7 CFLAR IF4G1 DAPLE ... PIBF1 PINK1 APOE NPRL2 BRAT1 STRAB TERA DKK1 SMAD4 OGT1 UCHL1 ANGI HDAC4 ERBB4 BDNF CD24 ABI1 NHLC1 ADNP PLPL9 | 5.8218 | |
| GO:0032270 | 68 ABCA7 VLDLR ATX3 TAU ANDR CFLAR IF4G1 PIBF1 PINK1 APOE ... BRAT1 STRAB DNJB2 TERA DKK1 VPS35 MBP SMAD4 OGT1 ANGI HDAC4 ERBB4 BDNF CD24 ABI1 KHDR1 CAN3 NHLC1 ADNP PLPL9 | 5.8218 | |
| GO:2000058 | 17 OGT1 LRRK2 CCD22 CAV3 UBQL4 CHIP UBQL2 PTEN PARK7 FHIT ... GLCM SUFU DNJB2 TERA PRKN TAF1 PSN1 | 5.7883 | |
| GO:0055082 | 38 LRRK2 FRIL ITPR1 EDN1 DPOG1 AFG32 CAC1C VAPB TM175 CCD22 ... CAV3 SL9A1 CAC1D APOE ATP7A SMAD4 SODC JPH3 AT1A3 CD24 XK AT132 CAN3 TRPV4 SYUA CAC1A SELT PLPL9 HD TRPM7 | 5.7272 | |
| GO:0055114 | 50 NDUS2 NDUB3 ODP2 NDUA2 NDUV2 PINK1 NDUF2 COQ7 NDUA9 CACP ... NDUA1 NDUS1 NDUAC WWOX NHLC1 NDUS7 NDUS6 CP4V2 ACON PAHX TMLH FRIL AAKG2 NU1M COQ9 NDUS3 PHF8 NDUAA NDUB9 MECP2 | 5.6858 | |
| GO:0042326 | 31 LRRK2 AAKG2 DSRAD TAU NDRG2 ASM CAV3 FBX7 IF4G1 PIBF1 ... PINK1 JIP1 APOE NPRL2 GLCM SORL DKK1 SMAD4 PRKN TADBP UCHL1 HDAC4 SYUA CI072 PTEN PARK7 PTPRC PPP5 PRIO RUBIC | 5.6857 | |
| GO:0042592 | 68 MKS1 DCTN1 ITPR1 DPOG1 DSRAD AFG32 IF4G1 APOE GGYF2 DNJB2 ... SMAD4 NPC1 NPC2 ANGI FHL1 ANK3 AT1A3 CD24 AT132 CAN3 CAC1A ADNP XRCC1 PLPL9 IL7RA HD SHAN3 AMPD2 PTPRC AT2B3 | 5.6603 | |
| GO:0010647 | 76 SYT9 ABCA7 DNM1L GRB14 ANDR CFLAR PIBF1 PINK1 APOE CASPA ... TERA DKK1 VPS35 TFG SMAD4 CHC10 ERBB4 BDNF BACD1 ANK3 CD24 WWOX KHDR1 PLPL9 IL7RA HD FCRL3 SHAN3 PTPRC DOC2B | 5.6575 | |
| GO:0010975 | 32 LRRK2 VLDLR DNM1L ADA10 TAU SYGP1 MARK1 FBX7 CFLAR FEZF2 ... T106B APOE SETX DKK1 PRKN BDNF ULK4 DAB1 XK GRID2 TRPV4 NLGN3 ADNP FIG4 PTEN SHAN3 NEUS TRAK2 SEM5A DREB | 5.6099 | |
| GO:0060284 | 48 LRRK2 EDN1 VLDLR DNM1L ADA10 TAU SYGP1 NKX62 CAV3 MARK1 ... FBX7 CFLAR IF4G1 FEZF2 T106B APOE SETX SORL DKK1 SMAD4 PRKN NOTC3 BC11B HDAC4 ERBB4 BDNF ULK4 DAB1 XK GRID2 | 5.5841 | |
| GO:0051705 | 12 SHAN2 PTHD1 PTEN SHAN3 MECP2 ATX1 NLGNX TY3H A4 CHD8 ... CNTP2 NLGN3 | 5.5762 | |
| GO:0050807 | 21 LRRK2 DCTN1 BDNF DNM1L ADA10 CHM2B GRID2 SYUA NLGN3 ADNP ... IF4G1 CTTB2 PTEN SHAN3 APOE DREB TERA DKK1 VPS35 A4 PRIO | 5.5629 | |
| GO:0061564 | 27 SPTN2 VLDLR TAU SIAH1 AFG32 TOP2B NFH ALS2 FEZF2 SMAD4 ... SPTCS BC11B UCHL1 RAPH1 BDNF ANK3 GDNF DAB1 UNC5C NLGN3 GPC1 AUTS2 CI072 PTEN SHAN3 SEM5A A4 | 5.5342 | |
| GO:0072507 | 29 ITPR1 EDN1 KCNA1 AFG32 CAC1C VAPB CAV3 CAC1D APOE PRKN ... JPH3 ANK3 CD24 XK AT132 CAN3 TRPV4 SYUA CAC1A SELT PLPL9 HD TRPM7 ATP7B PTPRC AT2B3 A4 GRM1 PSN1 | 5.5268 | |
| GO:0048878 | 50 ITPR1 DPOG1 AFG32 APOE SMAD4 NPC1 NPC2 FHL1 ANK3 AT1A3 ... CD24 AT132 CAN3 CAC1A ADNP PLPL9 HD PTPRC AT2B3 A4 GRM1 PSN1 LRRK2 FRIL EDN1 KCNA1 CAC1G CAC1C VAPB TM175 | 5.5088 | |
| GO:903364 | 16 LRRK2 ATX3 AMER1 CCD22 CAV3 CHIP UBQL2 PTEN APOE GLCM ... DNJB2 TERA VPS35 PRKN TAF1 PSN1 | 5.4715 | |
| GO:0007613 | 15 ABCA7 VLDLR JPH3 TAU ATX1 SCN2A ADNP PLPL9 PTEN SHAN3 ... APOE MECP2 TY3H PRIO PSN1 | 5.4715 | |
| GO:0061919 | 22 SQSTM LRRK2 SNX14 AAKG2 CHM2B AT132 OPTN NHLC1 UBQL4 FBX7 ... CHIP RB39B PINK1 CI072 ATG5 PARK7 GLCM TERA PRKN RUBIC PSN1 NPC1 | 5.4710 | |
| GO:0006914 | 22 SQSTM LRRK2 SNX14 AAKG2 CHM2B AT132 OPTN NHLC1 UBQL4 FBX7 ... CHIP RB39B PINK1 CI072 ATG5 PARK7 GLCM TERA PRKN RUBIC PSN1 NPC1 | 5.4710 | |
| GO:0048519 | 167 ABCA7 VLDLR DNM1L ADA10 DSRAD GRB14 TAU TYDP2 EXOS9 RERE ... DEPD5 FBX7 CFLAR IF4G1 PINK1 NDUF2 NLGNX STRAB ROA1 DNJB2 DKK1 VPS35 MBP SMAD4 TTBK2 NPC1 BC11B UCHL1 ANGI HDAC4 | 5.4710 | |
| GO:0051248 | 53 ABCA7 KPCG DSRAD TAU FBX7 CFLAR IF4G1 PIBF1 PINK1 APOE ... GGYF2 DKK1 VPS35 SMAD4 OGT1 UCHL1 ANGI AT132 CAN3 TNR6A XRCC1 CI072 PTPRC A4 PSN1 FLNA LRRK2 EDN1 AAKG2 ITM2B | 5.4690 | |
| GO:902531 | 76 ABCA7 ITPR1 DNM1L TAU SYGP1 ANDR DEPD5 CFLAR PINK1 APOE ... NPRL2 CASPA DKK1 TFG SMAD4 OGT1 UCHL1 ERBB4 BACD1 DIA1 CD24 CAN3 PLPL9 CI072 HD FCRL3 PTPRC TEN1 A4 GRM1 | 5.4651 | |
| GO:0006810 | 144 CACB4 SYT9 ABCA7 DCTN1 ASAH1 VLDLR DNM1L ADA10 TAU S52A3 ... SCN2A GTR1 FBX7 RB39B PINK1 SCN3A SCYL1 CACP STRAB ROA1 VPS35 TFG TIM14 S12A6 NPC1 SMN UCHL1 ERBB4 ANK3 AT1A3 | 5.4406 | |
| GO:0010822 | 15 DNM1L HTRA2 VP13D OPTN FBX7 PLPL9 PINK1 HD HUWE1 PARK7 ... GLCM CASP8 VPS35 PRKN CHC10 | 5.4394 | |
| GO:0009896 | 29 LRRK2 ATX3 TBK1 CCD22 OPTN CAV3 FBX7 UBQL2 PINK1 ATG5 ... APOE GGYF2 GLCM SORL DNJB2 TERA VPS35 PRKN PUM1 AMER1 VP13D SYUA CHIP CI072 HD PTEN PARK7 TAF1 PSN1 | 5.4384 | |
| GO:0007409 | 25 SPTN2 VLDLR SIAH1 AFG32 TOP2B NFH ALS2 FEZF2 SMAD4 SPTCS ... BC11B UCHL1 RAPH1 BDNF ANK3 GDNF DAB1 UNC5C NLGN3 GPC1 AUTS2 CI072 PTEN SHAN3 A4 | 5.3739 | |
| GO:0009895 | 24 TADBP NBAS OGT1 LRRK2 HDAC4 BSCL2 KPCG GDNF HTRA2 AT132 ... SYUA UBQL4 IF4G1 PINK1 MET PARK7 FHIT SUFU VPS35 TAF1 RUBIC PSN1 NPC1 FLNA | 5.3698 | |
| GO:0043067 | 68 ASAH1 KPCG DNM1L ADA10 DSRAD TAU SYGP1 ANDR CFLAR SGMR1 ... PINK1 CASPA PSN2 STRAB TERA DKK1 CHC10 BC11B HDAC4 MYP0 BDNF WDR73 DIA1 WWOX CAN3 WT1 HME2 ADNP PLPL9 IL7RA | 5.3212 | |
| GO:0023056 | 75 SYT9 ABCA7 DNM1L GRB14 ANDR CFLAR PIBF1 PINK1 APOE CASPA ... TERA DKK1 VPS35 TFG SMAD4 CHC10 ERBB4 BDNF BACD1 CD24 WWOX KHDR1 PLPL9 IL7RA HD FCRL3 SHAN3 PTPRC DOC2B TEN1 | 5.3148 | |
| GO:0031400 | 36 LRRK2 KPCG AAKG2 DSRAD TAU NDRG2 ASM CAV3 FBX7 IF4G1 ... PIBF1 PINK1 JIP1 PNKP ATG5 APOE GLCM SORL DKK1 SMAD4 PRKN DNMT1 TADBP OGT1 UCHL1 CAN3 SYUA XRCC1 CI072 PTEN | 5.3065 | |
| GO:0048167 | 18 SQSTM SHAN2 FGF14 JPH3 TAU SYGP1 GRID2 SYUA NLGN3 PTEN ... SHAN3 APOE MECP2 NEP DREB A4 PRIO PSN1 | 5.2815 | |
| GO:0042176 | 27 LRRK2 KPCG ATX3 CCD22 CAV3 UBQL2 PINK1 APOE GLCM SORL ... DNJB2 TERA VPS35 PRKN OGT1 AMER1 AT132 SYUA UBQL4 CHIP PTEN PARK7 FHIT SUFU TAF1 PSN1 FLNA | 5.2815 | |
| GO:0045664 | 37 LRRK2 VLDLR DNM1L ADA10 TAU SYGP1 MARK1 FBX7 CFLAR IF4G1 ... FEZF2 T106B APOE SETX DKK1 PRKN NOTC3 BC11B BDNF ULK4 DAB1 XK GRID2 TRPV4 NLGN3 ADNP FIG4 PTEN SHAN3 NEUS | 5.2635 | |
| GO:902903 | 25 SPTN2 DCTN1 EDN1 TAU CAV3 SL9A1 MET APOE MECP2 SMAD4 ... PRKN TTBK2 PROF1 TRPV4 SYUA CI072 SHAN3 PARK7 SEM5A TBB4A TEN1 A4 MAGL2 PSN1 FLNA | 5.2595 | |
| GO:0031401 | 55 ABCA7 VLDLR ANDR CFLAR IF4G1 PIBF1 PINK1 APOE BRAT1 STRAB ... TERA DKK1 SMAD4 OGT1 ANGI HDAC4 ERBB4 BDNF CD24 ABI1 NHLC1 ADNP PLPL9 FCRL3 PTPRC TEN1 A4 GRM1 PSN1 LRRK2 | 5.2538 | |
| GO:0051247 | 69 ABCA7 VLDLR ATX3 TAU ANDR CFLAR IF4G1 PIBF1 PINK1 APOE ... BRAT1 STRAB DNJB2 TERA DKK1 VPS35 MBP SMAD4 OGT1 ANGI HDAC4 ERBB4 BDNF CD24 ABI1 KHDR1 CAN3 NHLC1 ADNP PLPL9 | 5.2276 | |
| GO:0032269 | 50 KPCG DSRAD TAU FBX7 CFLAR IF4G1 PIBF1 PINK1 APOE GGYF2 ... DKK1 VPS35 SMAD4 OGT1 UCHL1 ANGI AT132 CAN3 TNR6A XRCC1 CI072 PTPRC A4 PSN1 LRRK2 EDN1 AAKG2 NDRG2 ASM CAV3 | 5.2260 | |
| GO:0009893 | 121 ABCA7 VLDLR DSRAD TAU EXOS9 RERE FBX7 CFLAR IF4G1 PINK1 ... CARTF STRAB ROA1 DNJB2 DKK1 VPS35 MBP SMAD4 BC11B ANGI HDAC4 ERBB4 BDNF ANK3 CD24 ABI1 CHCH2 TNR6A NHLC1 HME2 | 5.2075 | |
| GO:0031330 | 21 TADBP NBAS OGT1 LRRK2 KPCG GDNF HTRA2 AT132 SYUA UBQL4 ... IF4G1 PINK1 MET PARK7 FHIT SUFU VPS35 TAF1 RUBIC PSN1 NPC1 | 5.2027 | |
| GO:0010042 | 7 LRRK2 ATP7A TY3H AT132 A4 ARGI1 PRKN | 5.1947 | |
| GO:0009653 | 82 MKS1 VLDLR DNM1L AFG32 ANDR RERE CFLAR T106B APOE IF140 ... DKK1 SMAD4 S12A6 SPTCS NOTC3 BC11B UCHL1 ANGI SETD2 ERBB4 BDNF FHL1 ANK3 ABI1 WWOX CAN3 WT1 CNTP2 NUBPL XRCC1 | 5.1752 | |
| GO:0010038 | 26 LRRK2 EDN1 FUS KCNA1 TAU CAC1G ANX11 ATP7A CARTF CASP8 ... PRKN SODC NPC1 ANK3 ACTS AT132 CAN3 SYUA PTEN ATP7B PARK7 PPP5 TY3H A4 ARGI1 PRIO | 5.1741 | |
| GO:0001932 | 61 ABCA7 VLDLR DSRAD SYGP1 ANDR FBX7 CFLAR IF4G1 DAPLE PIBF1 ... PINK1 APOE BRAT1 STRAB DKK1 SMAD4 UCHL1 ANGI ERBB4 BDNF CD24 ABI1 NHLC1 ADNP PLPL9 CI072 HD FCRL3 PTPRC TEN1 | 5.1400 | |
| GO:0051234 | 146 CACB4 SYT9 ABCA7 DCTN1 ASAH1 VLDLR DNM1L ADA10 TAU S52A3 ... SCN2A GTR1 FBX7 RB39B PINK1 SCN3A SCYL1 CACP STRAB ROA1 VPS35 TFG TIM14 S12A6 NPC1 SMN UCHL1 ERBB4 ANK3 AT1A3 | 5.1319 | |
| GO:0007416 | 13 SHAN2 SPTN2 ERBB4 BDNF GRID2 NLGN3 PTEN SHAN3 MECP2 NLGNX ... PCLO VPS35 A4 | 5.1303 | |
| GO:0051960 | 46 MKS1 LRRK2 VLDLR DNM1L ADA10 TAU SYGP1 NKX62 MARK1 FBX7 ... CFLAR IF4G1 FEZF2 T106B APOE SETX SORL DKK1 VPS35 PRKN NOTC3 BC11B ERBB4 BDNF ULK4 DAB1 XK GRID2 TRPV4 SYUA | 5.0556 | |
| GO:0022898 | 21 CACB4 FGF14 FHL1 KCNA1 JPH3 ANK3 SYUA CAV3 SL9A1 NLGN3 ... PLPL9 CAC1D PINK1 HD PTEN SHAN3 PARK7 ATP7A A4 CHC10 PRIO | 5.0329 | |
| GO:990403 | 6 MKS1 IF140 SC6A8 RL10 HME2 TBC23 | 5.0140 | |
| GO:0016358 | 13 VLDLR ABI1 DAB1 SYGP1 RERE FEZF2 PTEN CTND2 SHAN3 T106B ... MECP2 TRAK2 A4 | 4.9678 | |
| GO:0050767 | 42 LRRK2 VLDLR DNM1L ADA10 TAU SYGP1 NKX62 MARK1 FBX7 CFLAR ... IF4G1 FEZF2 T106B APOE SETX SORL DKK1 PRKN NOTC3 BC11B ERBB4 BDNF ULK4 DAB1 XK GRID2 TRPV4 NLGN3 ADNP FIG4 | 4.9398 | |
| GO:0042981 | 66 KPCG DNM1L ADA10 DSRAD TAU SYGP1 ANDR CFLAR SGMR1 PINK1 ... CASPA PSN2 STRAB TERA DKK1 CHC10 BC11B HDAC4 MYP0 BDNF WDR73 DIA1 WWOX CAN3 WT1 HME2 ADNP PLPL9 IL7RA HD | 4.9268 | |
| GO:0043069 | 46 LRRK2 EDN1 KPCG DSRAD NDUS3 SYGP1 ANDR SL9A1 CFLAR PINK1 ... JIP1 MET ATG5 SETX MECP2 CASP8 STRAB DKK1 PRKN DNMT1 SODC SQSTM BC11B MYP0 BDNF PRDX2 WDR73 DIA1 GDNF HTRA2 | 4.7553 | |
| GO:0048513 | 111 MKS1 DCTN1 ASAH1 VLDLR DSRAD GTR1 RERE CFLAR IF4G1 ZSWM6 ... NLGNX DKK1 MBP SMAD4 TTBK2 TIM14 FRG1 BC11B ANGI SETD2 HDAC4 ERBB4 FHL1 CD24 ABI1 HME2 XRCC1 IL7RA PTPRC A4 | 4.7101 | |
| GO:0061136 | 17 OGT1 LRRK2 KPCG ATX3 UBQL4 CHIP UBQL2 PINK1 APOE PARK7 ... FHIT GLCM DNJB2 TERA PRKN TAF1 PSN1 | 4.7101 | |
| GO:0072593 | 13 LRRK2 EDN1 PRDX2 NDUS1 NDUS3 PRDX1 RORA NDUF2 PARK7 ATP7A ... NU2M NDUS4 SODC | 4.7101 | |
| GO:2000060 | 12 CHIP LRRK2 UBQL2 PTEN GLCM DNJB2 TERA CCD22 CAV3 PRKN ... TAF1 PSN1 | 4.6985 | |
| GO:0032409 | 21 CACB4 FGF14 FHL1 KCNA1 JPH3 ANK3 SYUA CAV3 SL9A1 NLGN3 ... PLPL9 CAC1D PINK1 HD PTEN SHAN3 PARK7 ATP7A A4 CHC10 PRIO | 4.6963 | |
| GO:0050806 | 15 SQSTM SYT9 SHAN2 BACD1 DNM1L SYUA NLGN3 CAC1D PINK1 PTEN ... SHAN3 MECP2 NEP EAA1 A4 | 4.6753 | |
| GO:0021549 | 13 SPTN2 CLP1 DAB1 RORA GRID2 ANAG RERE XRCC1 MECP2 NLGNX ... ATP7A TTBK2 PSN1 | 4.6671 | |
| GO:0010604 | 111 ABCA7 VLDLR DSRAD TAU EXOS9 RERE CFLAR IF4G1 PINK1 CARTF ... STRAB ROA1 DNJB2 DKK1 VPS35 MBP SMAD4 BC11B ANGI HDAC4 ERBB4 BDNF ANK3 CD24 ABI1 CHCH2 TNR6A NHLC1 HME2 ADNP | 4.6121 | |
| GO:0043066 | 45 LRRK2 EDN1 KPCG DSRAD NDUS3 SYGP1 ANDR SL9A1 CFLAR PINK1 ... JIP1 ATG5 SETX MECP2 CASP8 STRAB DKK1 PRKN DNMT1 SODC SQSTM BC11B MYP0 BDNF PRDX2 WDR73 DIA1 GDNF HTRA2 FOXP1 | 4.6081 | |
| GO:0001933 | 27 LRRK2 AAKG2 DSRAD NDRG2 ASM CAV3 FBX7 IF4G1 PIBF1 PINK1 ... JIP1 APOE GLCM SORL DKK1 SMAD4 PRKN TADBP UCHL1 SYUA CI072 PTEN PARK7 PTPRC PPP5 PRIO PSN1 | 4.5845 | |
| GO:0051338 | 46 LRRK2 EDN1 AAKG2 VLDLR DNM1L DSRAD TAU ASM CAV3 FBX7 ... PIBF1 PINK1 JIP1 ALS2 PNKP APOE NPRL2 GLCM STRAB SORL DKK1 PRKN SODC UCHL1 PPR3F ANGI BDNF PRDX2 CD24 ABI1 | 4.5739 | |
| GO:0032880 | 49 SYT9 ABCA7 ITPR1 DNM1L ADA10 TAU RBG1L GTR1 ANDR PINK1 ... NDUF2 APOE VPS35 MBP TTBK2 ANGI SETD2 ERBB4 BDNF ANK3 AT132 NHLC1 CAC1A PLPL9 DOC2B DREB TEN1 PSN1 FLNA LRRK2 | 4.5589 | |
| GO:0072503 | 26 ITPR1 EDN1 AFG32 CAC1C VAPB CAV3 CAC1D APOE JPH3 CD24 ... XK AT132 CAN3 TRPV4 SYUA CAC1A SELT PLPL9 HD TRPM7 ATP7B PTPRC AT2B3 A4 GRM1 PSN1 | 4.5587 | |
| GO:0031325 | 110 ABCA7 VLDLR TAU EXOS9 RERE FBX7 CFLAR IF4G1 PINK1 CARTF ... STRAB ROA1 DNJB2 DKK1 VPS35 MBP SMAD4 BC11B ANGI HDAC4 ERBB4 BDNF CD24 ABI1 CHCH2 NHLC1 HME2 ADNP XRCC1 PLPL9 | 4.5388 | |
| GO:0006812 | 41 CACB4 FRIL ITPR1 EDN1 KCNA1 DNM1L AFG32 CAC1G SCN2A CAC1C ... TM175 SL9A1 CAC1D SCN8A SCN3A SL9A9 ATP7A SC6A8 NDUA9 PRKN S17A5 MPPB JPH3 SC5A7 AT1A3 SURF1 MPPA AT132 TRPV4 SYUA | 4.5356 | |
| GO:0045862 | 24 OGT1 LRRK2 ATX3 TAU HTRA2 CAN3 SYUA CCD22 CAV3 CFLAR ... CHIP UBQL2 PINK1 PTEN APOE GLCM CASP8 DNJB2 TERA A4 MBP PRKN TAF1 PSN1 | 4.5199 | |
| GO:0061024 | 38 SYT9 OMA1 ABCA7 DCTN1 REEP3 DNM1L REPS1 VAPB CHM2B TM175 ... CAV3 SL9A1 VRK1 APOE NLGNX CASP8 VPS35 TFG MBP CHC10 SPTCS SODC VAMP1 NPC1 TADBP ANK3 GDNF CD24 SYNJ1 SYUA | 4.4418 | |
| GO:0016192 | 72 SYT9 ABCA7 DCTN1 ASAH1 VLDLR DNM1L ADA10 RBG1L TBC23 RB39B ... PINK1 APOE SCYL1 TERA VPS35 TFG SPTCS NPC1 NPC2 ANK3 TF2H2 ABI1 PLPL9 AUXI CI072 HD TRAK2 PTPRC DOC2B A4 | 4.4418 | |
| GO:903320 | 19 OGT1 LRRK2 HDAC4 KPCG DNM1L AMER1 CAN3 NHLC1 CHIP PINK1 ... PTEN ATG5 HUWE1 PARK7 DNJB2 TERA PRKN TAF1 PSN1 | 4.3577 | |
| GO:0006874 | 25 ITPR1 EDN1 AFG32 CAC1C VAPB CAV3 CAC1D APOE JPH3 CD24 ... XK AT132 CAN3 TRPV4 SYUA CAC1A SELT PLPL9 HD ATP7B PTPRC AT2B3 A4 GRM1 PSN1 | 4.3415 | |
| GO:0043549 | 42 LRRK2 EDN1 AAKG2 VLDLR DSRAD TAU ASM CAV3 FBX7 PIBF1 ... PINK1 JIP1 ALS2 APOE NPRL2 GLCM STRAB SORL DKK1 PRKN SODC UCHL1 ANGI BDNF PRDX2 CD24 ABI1 DAB1 SYUA NHLC1 | 4.3414 | |
| GO:0019220 | 69 ABCA7 VLDLR DSRAD TAU SYGP1 ANDR FBX7 CFLAR IF4G1 DAPLE ... PIBF1 PINK1 APOE NPRL2 BRAT1 STRAB TERA DKK1 SMAD4 OGT1 UCHL1 ANGI HDAC4 ERBB4 BDNF CD24 ABI1 NHLC1 ADNP PLPL9 | 4.2837 | |
| GO:0006878 | 5 ATP7B ATP7A A4 CCD22 PRIO | 4.2722 | |
| GO:990535 | 5 DCTN1 AT1A3 A4 PRIO PSN1 | 4.2722 | |
| GO:0051174 | 69 ABCA7 VLDLR DSRAD TAU SYGP1 ANDR FBX7 CFLAR IF4G1 DAPLE ... PIBF1 PINK1 APOE NPRL2 BRAT1 STRAB TERA DKK1 SMAD4 OGT1 UCHL1 ANGI HDAC4 ERBB4 BDNF CD24 ABI1 NHLC1 ADNP PLPL9 | 4.2722 | |
| GO:0043270 | 21 FGF14 ABCA7 FHL1 EDN1 KCNA1 ANK3 GDNF CAN3 SYUA SL9A1 ... NLGN3 PLPL9 CAC1D PINK1 HD SHAN3 APOE PARK7 CHC10 PSN1 FLNA | 4.2722 | |
| GO:0007612 | 15 SHAN2 JPH3 ATX1 SYGP1 SYNJ1 CNTP2 NLGN3 HD SHAN3 MECP2 ... NLGNX TY3H DKK1 A4 PRKN | 4.2722 | |
| GO:0022037 | 13 SPTN2 CLP1 DAB1 RORA GRID2 ANAG RERE XRCC1 MECP2 NLGNX ... ATP7A TTBK2 PSN1 | 4.2708 | |
| GO:0051239 | 109 MKS1 CACB4 ABCA7 VLDLR DNM1L ADA10 TAU FBX7 CFLAR IF4G1 ... T106B NLGNX RPC2 DKK1 VPS35 MBP SMAD4 BC11B SETD2 HDAC4 ERBB4 BDNF AT1A3 CD24 TNR6A ADNP IL7RA FIG4 TRAK2 PTPRC | 4.2697 | |
| GO:0070925 | 34 MKS1 DCTN1 ATX10 ARMC9 TAU CHM2B TM175 ARL3 POGZ CFLAR ... ATX2 TM237 PIBF1 ATG5 IF140 NPHP1 MYPN TTBK2 SPTCS B9D2 ACTS NEK1 CAN3 B9D1 RS23 CI072 PTEN SHAN3 TBA4A TBB4A | 4.2697 | |
| GO:901524 | 6 VP13C PINK1 HTRA2 VP13D OPTN PRKN | 4.2697 | |
| GO:902532 | 30 LRRK2 ITPR1 NDUS3 NDRG2 SYGP1 RORA ASM CCD22 OPTN CAV3 ... DEPD5 PINK1 JIP1 MET APOE NPRL2 GLCM CASP8 SORL SMAD4 PRKN UCHL1 BACD1 HTRA2 LITAF PTEN PARK7 PTPRC NPRL3 PRIO | 4.2558 | |
| GO:903052 | 13 LRRK2 ATX3 CCD22 CAV3 CHIP UBQL2 PTEN GLCM DNJB2 TERA ... PRKN TAF1 PSN1 | 4.2348 | |
| GO:0046907 | 57 SYT9 DCTN1 DNM1L TAU ATX1 TBC23 FBX7 APOE IF140 CACP ... STRAB ROA1 TERA VPS35 TFG TIM14 SPTCS NPC1 SMN NPC2 UCHL1 ANK3 CD24 HD TRAK2 DOC2B PAHX A4 RL10 PSN1 | 4.2318 | |
| GO:0099003 | 12 SYT9 AUXI TM230 DNM1L SYNJ1 DOC2B PCLO VPS35 SYUA PSN1 ... SPTCS VAMP1 | 4.2188 | |
| GO:0044093 | 69 APCL VLDLR DNM1L TAU SYGP1 ANDR DEPD5 CFLAR IF4G1 PIBF1 ... PINK1 APOE NPRL2 PSN2 STRAB DNJB2 TERA DKK1 MBP CHC10 TIM14 ANGI HDAC4 BDNF ANK3 TF2H2 CD24 ABI1 CAN3 ADNP | 4.1986 | |
| GO:0006836 | 15 SYT9 EDN1 SC5A7 S6A19 SYNJ1 SYUA PARK7 SC6A8 DOC2B PCLO ... TY3H EAA1 PRKN PSN1 VAMP1 | 4.1779 | |
| GO:0032434 | 13 OGT1 LRRK2 UBQL4 CHIP UBQL2 PARK7 FHIT GLCM DNJB2 TERA ... PRKN TAF1 PSN1 | 4.1540 | |
| GO:0030902 | 15 SPTN2 CLP1 DAB1 RORA GRID2 ANAG RERE HME2 XRCC1 MECP2 ... NLGNX ATP7A TTBK2 PSN1 FLNA | 4.1443 | |
| GO:0032412 | 19 CACB4 FGF14 FHL1 KCNA1 JPH3 ANK3 CAV3 SL9A1 NLGN3 PLPL9 ... CAC1D PINK1 HD PTEN SHAN3 ATP7A A4 CHC10 PRIO | 4.1377 | |
| GO:0055074 | 25 ITPR1 EDN1 AFG32 CAC1C VAPB CAV3 CAC1D APOE JPH3 CD24 ... XK AT132 CAN3 TRPV4 SYUA CAC1A SELT PLPL9 HD ATP7B PTPRC AT2B3 A4 GRM1 PSN1 | 4.0808 | |
| GO:0071248 | 16 LRRK2 EDN1 FUS KCNA1 ANK3 AT132 CAN3 SYUA ATP7A CARTF ... PPP5 TY3H A4 PRKN PRIO SODC | 4.0808 | |
| GO:0099173 | 11 SPTN2 PTEN GDNF ADA10 CTND2 SHAN3 APOE SYGP1 PRIO NFH ... NLGN3 | 4.0392 | |
| GO:0099175 | 12 LRRK2 DNM1L PTEN ADA10 SHAN3 APOE CHM2B DREB GRID2 VPS35 ... PRIO NLGN3 | 4.0384 | |
| GO:0051050 | 46 SYT9 FGF14 LRRK2 ABCA7 EDN1 KCNA1 DNM1L CAV3 SL9A1 CAC1D ... PINK1 ATG5 APOE HUWE1 CASP8 SORL VPS35 MBP SMAD4 PRKN CHC10 SODC TADBP ANGI FHL1 ANK3 GDNF HTRA2 KHDR1 AT132 | 4.0352 | |
| GO:0106027 | 8 DCTN1 PTEN CTND2 SHAN3 AT1A3 A4 PRIO PSN1 | 4.0352 | |
| GO:0009892 | 98 ABCA7 VLDLR DSRAD TAU TYDP2 EXOS9 RERE FBX7 CFLAR IF4G1 ... PINK1 ROA1 DKK1 VPS35 SMAD4 NPC1 UCHL1 ANGI HDAC4 TNR6A ADNP XRCC1 PTPRC A4 RL10 PSN1 LRRK2 EDN1 ITM2B NDRG2 | 4.0002 | |
| GO:0009966 | 114 MKS1 ABCA7 DNM1L DSRAD GRB14 TAU DEPD5 CFLAR PINK1 NLGNX ... CASPA STRAB DKK1 VPS35 TFG SMAD4 UCHL1 ERBB4 BDNF TF2H2 CD24 UBA5 PLPL9 IL7RA HD PTPRC A4 GRM1 PSN1 LRRK2 | 3.9934 | |
| GO:0045732 | 17 LRRK2 ATX3 AMER1 CCD22 CAV3 CHIP UBQL2 PTEN APOE GLCM ... SORL DNJB2 TERA VPS35 PRKN TAF1 PSN1 | 3.9934 | |
| GO:0098780 | 6 SQSTM PINK1 HTRA2 GLCM OPTN PRKN | 3.9838 | |
| GO:0010605 | 91 ATN1 ABCA7 KPCG VLDLR DSRAD TAU ATX1 TYDP2 EXOS9 ANDR ... RERE FBX7 CFLAR IF4G1 PIBF1 PINK1 APOE GGYF2 ROA1 DKK1 VPS35 SMAD4 NOTC3 OGT1 UCHL1 ANGI HDAC4 PPM1D WWOX KHDR1 | 3.9635 | |
| GO:0030900 | 25 LRRK2 KCNA1 TOP2B GTR1 ZSWM6 FEZF2 ATP7A DKK1 CE120 NOTC3 ... BC11B SETD2 ERBB4 HTRA2 DAB1 CNTP2 XRCC1 PTHD1 PTEN SHAN3 SEM5A TY3H A4 PSN1 FLNA | 3.9536 | |
| GO:0031324 | 88 ATN1 ABCA7 KPCG VLDLR DSRAD TAU ATX1 TYDP2 ANDR RERE ... FBX7 CFLAR IF4G1 PIBF1 PINK1 APOE NPRL2 GGYF2 ROA1 DKK1 VPS35 SMAD4 NPC1 NOTC3 OGT1 UCHL1 ANGI HDAC4 PPM1D WWOX | 3.9301 | |
| GO:0048518 | 179 SYT9 ABCA7 DCTN1 VLDLR DNM1L ADA10 DSRAD GRB14 TAU EXOS9 ... RERE FBX7 CFLAR IF4G1 PINK1 T106B CARTF CASPA RPC2 PSN2 STRAB ROA1 DNJB2 DKK1 VPS35 TFG MBP SMAD4 BC11B ANGI | 3.9289 | |
| GO:0051656 | 24 KIF5A SYT9 TM230 UCHL1 DCTN1 KIF1C TAU BICD2 SYNJ1 CHM2B ... SYUA TBC23 MARK1 PIBF1 HD TRAK2 DOC2B PCLO TFG CE120 PSN1 SPTCS VAMP1 CHM1A | 3.9171 | |
| GO:0051173 | 103 ABCA7 VLDLR TAU EXOS9 RERE CFLAR IF4G1 PINK1 CARTF STRAB ... ROA1 DNJB2 DKK1 VPS35 MBP SMAD4 BC11B ANGI HDAC4 ERBB4 BDNF CD24 ABI1 CHCH2 NHLC1 HME2 ADNP XRCC1 PLPL9 PTPRC | 3.9074 | |
| GO:0071241 | 17 LRRK2 EDN1 FUS KCNA1 ANK3 AT132 CAN3 SYUA CFLAR ATP7A ... CARTF PPP5 TY3H A4 PRKN PRIO SODC | 3.8860 | |
| GO:0051148 | 9 CFLAR HDAC4 BDNF MECP2 CTDP1 DKK1 SMAD4 CAV3 DNMT1 | 3.8802 | |
| GO:0008366 | 12 GPC1 MYP0 SCN8A FIG4 PTEN AFG32 XK SCN2A MYPR NKX62 ... MBP SODC | 3.8802 | |
| GO:0007272 | 12 GPC1 MYP0 SCN8A FIG4 PTEN AFG32 XK SCN2A MYPR NKX62 ... MBP SODC | 3.8802 | |
| GO:0045859 | 38 LRRK2 EDN1 AAKG2 VLDLR DSRAD ASM CAV3 FBX7 PIBF1 PINK1 ... JIP1 ALS2 APOE GLCM STRAB SORL DKK1 SODC UCHL1 ANGI BDNF PRDX2 CD24 ABI1 DAB1 SYUA NHLC1 ADNP HD PTEN | 3.8786 | |
| GO:901663 | 5 COQ2 COQ9 COQ7 COQ8A DLP1 | 3.8680 | |
| GO:0071287 | 5 LRRK2 TY3H AT132 A4 PRKN | 3.8680 | |
| GO:0006744 | 5 COQ2 COQ9 COQ7 COQ8A DLP1 | 3.8680 | |
| GO:0070050 | 7 FGGY DCTN1 CAC1D CHM2B AT2B3 DNJB2 PRKN | 3.8508 | |
| GO:0048522 | 159 SYT9 ABCA7 DCTN1 VLDLR DNM1L ADA10 GRB14 TAU EXOS9 RERE ... FBX7 CFLAR IF4G1 PINK1 T106B CARTF CASPA PSN2 STRAB ROA1 DNJB2 DKK1 VPS35 TFG MBP SMAD4 BC11B ANGI HDAC4 ERBB4 | 3.8311 | |
| GO:0045936 | 31 LRRK2 AAKG2 DSRAD TAU NDRG2 ASM CAV3 FBX7 IF4G1 PIBF1 ... PINK1 JIP1 APOE NPRL2 GLCM SORL DKK1 SMAD4 PRKN TADBP UCHL1 HDAC4 SYUA CI072 PTEN PARK7 PTPRC PPP5 PRIO RUBIC | 3.7965 | |
| GO:0031346 | 24 HDAC4 BDNF VLDLR PROF1 DNM1L TAU ADNP CFLAR AUTS2 FIG4 ... HD SHAN3 T106B APOE SETX NEUS ATP7A SEM5A DREB TEN1 FBX38 PRKN CE120 PSN1 | 3.7938 | |
| GO:0030001 | 32 CACB4 FRIL ITPR1 KCNA1 DNM1L AFG32 CAC1G SCN2A CAC1C TM175 ... SL9A1 CAC1D SCN8A SCN3A ATP7A SC6A8 NDUA9 MPPB JPH3 SC5A7 AT1A3 MPPA TRPV4 CAC1A TRPM7 KCND2 ATP7B PTPRC AT2B3 EAA1 | 3.7922 | |
| GO:0010563 | 31 LRRK2 AAKG2 DSRAD TAU NDRG2 ASM CAV3 FBX7 IF4G1 PIBF1 ... PINK1 JIP1 APOE NPRL2 GLCM SORL DKK1 SMAD4 PRKN TADBP UCHL1 HDAC4 SYUA CI072 PTEN PARK7 PTPRC PPP5 PRIO RUBIC | 3.7854 | |
| GO:0006950 | 112 DCTN1 NDUS2 DNM1L DSRAD TAU S52A3 SCN2A TYDP2 GTR1 DEPD5 ... CFLAR IF4G1 DAPLE PINK1 RPC2 PSN2 ROA1 DNJB2 SMAD4 S12A6 UCHL1 ANGI SETD2 HDAC4 ERBB4 NDUAC TF2H2 CD24 UBA5 NEK1 | 3.7563 | |
| GO:0098662 | 28 CACB4 ITPR1 KCNA1 AFG32 CAC1G SCN2A CAC1C TM175 SL9A1 CAC1D ... SL9A9 ATP7A S17A5 MPPB JPH3 AT1A3 SURF1 MPPA TRPV4 CAC1A TRPM7 KCND2 ATP7B PTPRC AT2B3 EAA1 KCNC3 PSN1 | 3.7545 | |
| GO:0043523 | 17 HDAC4 KPCG GDNF SYGP1 GRID2 SYUA HME2 ADNP SGMR1 PINK1 ... PARK7 MECP2 BIRC1 PRKN PRIO PSN1 SODC | 3.7083 | |
| GO:0050805 | 9 PLPL9 SHAN2 LRRK2 PTEN NLGNX SYUA PRKN NLGN3 ADNP | 3.7061 | |
| GO:0001505 | 22 SYT9 LRRK2 EDN1 KPCG DNM1L SC5A7 GDNF SYNJ1 RORA SYUA ... CAC1D DGLA PARK7 SNCAP ATP7A DOC2B PCLO TY3H EAA1 PRKN PSN1 VAMP1 | 3.7061 | |
| GO:904923 | 5 PINK1 HTRA2 GLCM OPTN PRKN | 3.6899 | |
| GO:0055070 | 5 ATP7B ATP7A A4 CCD22 PRIO | 3.6899 | |
| GO:0006743 | 5 COQ2 COQ9 COQ7 COQ8A DLP1 | 3.6899 | |
| GO:0046688 | 7 ATP7B PARK7 ATP7A SYUA A4 PRIO SODC | 3.6745 | |
| GO:0090647 | 4 DKK1 A4 PRIO PSN1 | 3.5944 | |
| GO:0048583 | 139 MKS1 ABD12 ABCA7 DNM1L ADA10 DSRAD GRB14 TAU DEPD5 FBX7 ... CFLAR IF4G1 PINK1 NDUF2 NLGNX CASPA RPC2 STRAB DKK1 VPS35 TFG SMAD4 UCHL1 SETD2 HDAC4 ERBB4 BDNF TF2H2 CD24 UBA5 | 3.5775 | |
| GO:0033673 | 18 UCHL1 AAKG2 DSRAD TAU ASM CAV3 FBX7 JIP1 PTEN APOE ... PARK7 NPRL2 GLCM PTPRC SORL PRKN RUBIC PSN1 | 3.5469 | |
| GO:0021695 | 8 SPTN2 CLP1 ATP7A RORA GRID2 ANAG RERE TTBK2 | 3.5391 | |
| GO:0031648 | 8 DAPLE HD SIAH1 CAN3 VPS35 SYUA PRKN PRIO | 3.5391 | |
| GO:0070201 | 37 SYT9 LRRK2 ITPR1 DNM1L TAU CAC1C GTR1 CAC1D PINK1 NDUF2 ... ATG5 APOE HUWE1 CASP8 SORL VPS35 MBP PRKN CE120 TADBP ANGI SETD2 ANK3 HTRA2 FOXP1 AT132 FRM4A TRPV4 CAC1A PLPL9 | 3.5361 | |
| GO:0060627 | 28 SYT9 LRRK2 ABCA7 KPCG DNM1L DJC13 CAV3 ATX2 CAC1D UBQL2 ... PINK1 ATG5 APOE PCLO SORL DKK1 PRKN CAD13 SODC VAMP1 AT132 SYUA PLPL9 AUXI PTEN PTPRC DOC2B RUBIC | 3.5360 | |
| GO:0051240 | 67 ABCA7 VLDLR DNM1L TAU ANDR TBC23 CFLAR IF4G1 PIBF1 T106B ... APOE RPC2 DKK1 MBP SMAD4 OGT1 SETD2 HDAC4 ERBB4 BDNF CD24 WT1 ADNP GPC1 IL7RA FIG4 SHAN3 PTPRC DREB FBX38 | 3.5218 | |
| GO:0090140 | 6 LRRK2 PINK1 DNM1L TAU VPS35 PRKN | 3.5148 | |
| GO:0099075 | 3 PINK1 VPS35 PRKN | 3.5141 | |
| GO:0099074 | 3 PINK1 VPS35 PRKN | 3.5141 | |
| GO:0051583 | 3 PARK7 SYUA PRKN | 3.5141 | |
| GO:0051934 | 3 PARK7 SYUA PRKN | 3.5141 | |
| GO:0099504 | 10 SYT9 AUXI DNM1L SYNJ1 DOC2B PCLO TY3H SYUA PSN1 VAMP1 | 3.5083 | |
| GO:0034767 | 14 FGF14 KCNA1 ANK3 CAN3 SYUA SL9A1 NLGN3 PINK1 HD SHAN3 ... PARK7 CHC10 PSN1 FLNA | 3.4934 | |
| GO:0042327 | 44 LRRK2 ABCA7 EDN1 AAKG2 VLDLR TAU TBK1 ANDR CFLAR IF4G1 ... PIBF1 PINK1 JIP1 ALS2 APOE BRAT1 STRAB TERA DKK1 SMAD4 SODC SQSTM ANGI ERBB4 BDNF PRDX2 CD24 ABI1 DAB1 TRPV4 | 3.4801 | |
| GO:0044281 | 66 COQ2 ASAH1 VLDLR ODP2 S52A3 TPK1 GTR1 SYRM SYDM APOE ... COQ7 BRAT1 PURA1 CACP TERA NPC1 NPC2 ELOV4 SYAM S35A3 SYMM NDUS6 CP4V2 ACON DGLA AMPD2 BCKD PAHX A4 FGGY | 3.4801 | |
| GO:0031396 | 16 OGT1 LRRK2 KPCG DNM1L AMER1 NHLC1 CHIP PINK1 PTEN ATG5 ... HUWE1 PARK7 DNJB2 PRKN TAF1 PSN1 | 3.4597 | |
| GO:0010721 | 21 NOTC3 LRRK2 ERBB4 DAB1 SYGP1 NKX62 TRPV4 CAV3 NLGN3 FEZF2 ... PTEN APOE CTDP1 TRAK2 SEM5A SORL DKK1 A4 SMAD4 PSN1 IF4E | 3.4471 | |
| GO:0051961 | 20 NOTC3 LRRK2 ERBB4 DAB1 SYGP1 NKX62 TRPV4 NLGN3 FIG4 FEZF2 ... PTEN APOE TRAK2 SEM5A SUFU SORL DKK1 A4 PSN1 IF4E | 3.4373 | |
| GO:0030162 | 34 LRRK2 KPCG ATX3 TAU CCD22 CAV3 CFLAR UBQL2 PINK1 APOE ... GLCM CASP8 SORL DNJB2 TERA MBP PRKN T4S20 OGT1 HTRA2 AT132 CAN3 SYUA UBQL4 CHIP PTEN PARK7 FHIT BIRC1 SUFU | 3.4343 | |
| GO:902533 | 44 LRRK2 ABCA7 EDN1 DNM1L SIAH1 TBK1 CCD22 ANDR SL9A1 CFLAR ... PINK1 JIP1 ALS2 MET APOE CASPA CASP8 DKK1 TFG PRKN CAD13 SODC PUM1 ERBB4 PRDX2 CD24 TRPV4 PLPL9 AUTS2 TNR1A | 3.4122 | |
| GO:0010562 | 46 LRRK2 ABCA7 EDN1 AAKG2 VLDLR TAU TBK1 ASM ANDR CFLAR ... IF4G1 PIBF1 PINK1 JIP1 ALS2 APOE BRAT1 GLCM STRAB TERA DKK1 SMAD4 SODC SQSTM ANGI ERBB4 BDNF PRDX2 CD24 ABI1 | 3.4122 | |
| GO:0045937 | 46 LRRK2 ABCA7 EDN1 AAKG2 VLDLR TAU TBK1 ASM ANDR CFLAR ... IF4G1 PIBF1 PINK1 JIP1 ALS2 APOE BRAT1 GLCM STRAB TERA DKK1 SMAD4 SODC SQSTM ANGI ERBB4 BDNF PRDX2 CD24 ABI1 | 3.4122 | |
| GO:0097480 | 9 SYT9 TM230 SYNJ1 DOC2B PCLO SYUA PSN1 SPTCS VAMP1 | 3.3909 | |
| GO:0048489 | 9 SYT9 TM230 SYNJ1 DOC2B PCLO SYUA PSN1 SPTCS VAMP1 | 3.3909 | |
| GO:0006388 | 5 SEN34 CLP1 SEN2 SEN54 SEN15 | 3.3844 | |
| GO:0006811 | 53 CACB4 ABCA7 ITPR1 DNM1L S52A3 AFG32 SCN2A GTR1 CLCN2 SCN8A ... SCN3A APOE NDUA9 S12A6 NPC2 SC5A7 AT1A3 AT132 S35A3 CAC1A ANO10 PTPRC AT2B3 PSN1 FRIL EDN1 AAKG2 KCNA1 CAC1G S6A19 | 3.3844 | |
| GO:0051172 | 80 ATN1 ABCA7 KPCG VLDLR DSRAD TAU ATX1 TYDP2 ANDR RERE ... FBX7 CFLAR IF4G1 PIBF1 PINK1 APOE GGYF2 ROA1 DKK1 VPS35 SMAD4 NOTC3 OGT1 UCHL1 ANGI HDAC4 PPM1D WWOX KHDR1 AT132 | 3.3806 | |
| GO:0010769 | 19 LRRK2 BDNF DNM1L ADA10 TAU DAB1 SYGP1 XK NLGN3 ADNP ... FEZF2 PTEN SHAN3 APOE TRAK2 SEM5A DREB PSN1 FLNA | 3.3806 | |
| GO:0010508 | 12 LRRK2 PINK1 CI072 HD ATG5 PARK7 GLCM VP13D TBK1 OPTN ... PRKN FBX7 | 3.3742 | |
| GO:0001934 | 42 LRRK2 ABCA7 EDN1 AAKG2 VLDLR TBK1 ANDR CFLAR IF4G1 PIBF1 ... PINK1 JIP1 ALS2 APOE BRAT1 STRAB DKK1 SMAD4 SODC SQSTM ANGI ERBB4 BDNF PRDX2 CD24 ABI1 DAB1 TRPV4 SYUA ADNP | 3.3742 | |
| GO:0043085 | 55 APCL VLDLR DNM1L TAU SYGP1 DEPD5 CFLAR PIBF1 PINK1 APOE ... NPRL2 PSN2 STRAB DNJB2 TERA DKK1 MBP CHC10 TIM14 ANGI BDNF TF2H2 CD24 ABI1 ADNP XRCC1 FCRL3 PTPRC TEN1 A4 | 3.3217 | |
| GO:0007033 | 11 LRRK2 FIG4 ATG5 TPP1 GLCM TM175 AT132 ANAG VPS35 PSN1 ... SPTCS | 3.2971 | |
| GO:0051154 | 7 CFLAR HDAC4 BDNF CTDP1 DKK1 SMAD4 CAV3 | 3.2890 | |
| GO:2001233 | 24 LRRK2 BDNF PRDX2 DNM1L GDNF NDUS3 SIAH1 HTRA2 WWOX ANDR ... CFLAR PLPL9 PINK1 JIP1 HD PTEN PARK7 PTPRC CASP8 STRAB PRKN CHC10 PSN1 SODC | 3.2877 | |
| GO:0070588 | 15 CACB4 ITPR1 MPPB JPH3 AFG32 CAC1G MPPA CAC1C TRPV4 CAC1A ... CAC1D TRPM7 PTPRC AT2B3 PSN1 | 3.2865 | |
| GO:904064 | 13 FGF14 KCNA1 ANK3 CAN3 SYUA SL9A1 NLGN3 PINK1 HD SHAN3 ... PARK7 CHC10 FLNA | 3.2730 | |
| GO:0003008 | 72 ABCA7 DCTN1 KPCG VLDLR DNM1L TAU S52A3 ATX1 SYGP1 SCN2A ... ANDR CFLAR APOE NLGNX GGYF2 DKK1 MBP TIM14 UCHL1 HDAC4 ANK3 UBA5 CNTP2 ADNP PLPL9 NDUS6 CP4V2 HD SHAN3 A4 | 3.2496 | |
| GO:0000394 | 5 SEN34 CLP1 SEN2 SEN54 SEN15 | 3.2496 | |
| GO:0050769 | 26 VLDLR DNM1L TAU NKX62 CFLAR IF4G1 FEZF2 T106B APOE SETX ... DKK1 PRKN BDNF DAB1 ADNP FIG4 PTEN SHAN3 NEUS SEM5A NEP DREB FBX38 A4 PSN1 FLNA | 3.2496 | |
| GO:0009612 | 16 ABD12 HDAC4 EDN1 KCNA1 ACTS GTR1 TRPV4 CNTP2 CAV3 SL9A1 ... TNR1A HD SHAN3 CASP8 CRADD EAA1 | 3.2202 | |
| GO:902905 | 15 DCTN1 EDN1 PROF1 TAU TRPV4 CAV3 MET APOE MECP2 SEM5A ... TEN1 A4 MAGL2 PSN1 FLNA | 3.2091 | |
| GO:0050877 | 55 ABCA7 DCTN1 KPCG VLDLR TAU S52A3 ATX1 SYGP1 SCN2A APOE ... NLGNX GGYF2 DKK1 MBP TIM14 UCHL1 ANK3 UBA5 CNTP2 ADNP PLPL9 CP4V2 HD SHAN3 A4 GRM1 PSN1 SHAN2 LRRK2 EDN1 | 3.2070 | |
| GO:0097479 | 9 SYT9 TM230 SYNJ1 DOC2B PCLO SYUA PSN1 SPTCS VAMP1 | 3.1989 | |
| GO:903169 | 13 CACB4 FGF14 JPH3 CAC1C CAN3 SYUA CAV3 SL9A1 PLPL9 HD ... ATG5 PSN2 PRIO | 3.1840 | |
| GO:0031647 | 19 TADBP LRRK2 PROF1 APTX SIAH1 CAN3 SYUA FBX7 CHIP DAPLE ... PINK1 HD PTEN PARK7 VPS35 PRKN PRIO TAF1 FLNA | 3.1788 | |
| GO:0045666 | 22 BDNF VLDLR DNM1L TAU DAB1 ADNP CFLAR IF4G1 FIG4 FEZF2 ... PTEN SHAN3 T106B APOE SETX NEUS SEM5A DREB FBX38 DKK1 PRKN PSN1 | 3.1716 | |
| GO:0007017 | 29 KIF5A APCL DCTN1 KIF1C ATX7 ATX3 TAU TBCE ARL3 CAV3 ... MARK1 NFH PIBF1 IF140 MECP2 TTBK2 CE120 SPTCS SODC UCHL1 SETD2 ULK4 WDR73 BICD2 TRPV4 HD TRAK2 A4 FLNA | 3.1646 | |
| GO:0043524 | 13 KPCG GDNF SYGP1 SYUA HME2 ADNP PINK1 PARK7 MECP2 BIRC1 ... PRKN PSN1 SODC | 3.1567 | |
| GO:0032436 | 9 CHIP LRRK2 UBQL2 GLCM DNJB2 TERA PRKN TAF1 PSN1 | 3.1550 | |
| GO:901526 | 4 PINK1 VP13D OPTN PRKN | 3.1322 | |
| GO:0044248 | 61 ABD12 ABCA7 ASAH1 VLDLR ATX3 EXOS9 FBX7 IF4G1 RB39B PINK1 ... CACP TERA NPC1 UCHL1 BACD1 AT132 PLPL6 NHLC1 GPC1 CI072 DGLA BCKD FBX38 PAHX RL10 PSN1 LRRK2 SNX14 OMA1 AAKG2 | 3.1200 | |
| GO:0031110 | 9 DCTN1 MET TAU MECP2 TBB4A TRPV4 SYUA CAV3 TTBK2 | 3.1077 | |
| GO:0051962 | 28 VLDLR DNM1L TAU NKX62 CFLAR IF4G1 FEZF2 T106B APOE SETX ... DKK1 PRKN BDNF DAB1 GRID2 NLGN3 ADNP FIG4 PTEN SHAN3 NEUS SEM5A NEP DREB FBX38 A4 PSN1 FLNA | 3.0963 | |
| GO:0051223 | 34 SYT9 LRRK2 ITPR1 DNM1L CAC1C GTR1 CAC1D PINK1 NDUF2 ATG5 ... APOE HUWE1 SORL VPS35 MBP PRKN TADBP ANGI SETD2 ANK3 HTRA2 FOXP1 AT132 FRM4A TRPV4 CAC1A PLPL9 PARK7 SUFU DOC2B | 3.0962 | |
| GO:0090087 | 35 SYT9 LRRK2 ITPR1 DNM1L CAC1C GTR1 CAC1D PINK1 NDUF2 ATG5 ... APOE HUWE1 SORL VPS35 MBP PRKN TADBP ANGI SETD2 ANK3 HTRA2 FOXP1 AT132 FRM4A TRPV4 CAC1A SELT PLPL9 PARK7 SUFU | 3.0931 | |
| GO:0051899 | 7 CACB4 CAC1D EDN1 PARK7 CAC1G CAC1C CAC1A | 3.0921 | |
| GO:0048813 | 8 VLDLR PTEN CTND2 SHAN3 T106B ABI1 TRAK2 RERE | 3.0921 | |
| GO:0098655 | 28 CACB4 ITPR1 KCNA1 AFG32 CAC1G SCN2A CAC1C TM175 SL9A1 CAC1D ... SL9A9 ATP7A S17A5 MPPB JPH3 AT1A3 SURF1 MPPA TRPV4 CAC1A TRPM7 KCND2 ATP7B PTPRC AT2B3 EAA1 KCNC3 PSN1 | 3.0729 | |
| GO:0060998 | 9 LRRK2 DNM1L PTEN ADA10 SHAN3 APOE DREB PSN1 NLGN3 | 3.0667 | |
| GO:0001964 | 6 KCNA1 PTEN MECP2 GRID2 CHD8 PRKN | 3.0666 | |
| GO:0007528 | 6 LRRK2 DCTN1 ALS2 ANK3 AFG32 A4 | 3.0666 | |
| GO:0009056 | 68 ABD12 ABCA7 ASAH1 VLDLR ATX3 EXOS9 PLD3 FBX7 IF4G1 RB39B ... PINK1 CACP TERA NPC1 UCHL1 BACD1 AT132 CAN3 PLPL6 NHLC1 PLPL9 GPC1 CI072 DGLA BCKD FBX38 PAHX RL10 PSN1 LRRK2 | 3.0646 | |
| GO:0010639 | 21 LRRK2 OMA1 SPTN2 PROF1 DNM1L TAU HTRA2 PHF8 SYUA CAV3 ... XRCC1 PINK1 MET ATG5 SHAN3 TBB4A ROA1 SMAD4 PRKN TTBK2 DNMT1 | 3.0645 | |
| GO:2000026 | 73 MKS1 VLDLR DNM1L ADA10 TAU SYGP1 ANDR FBX7 CFLAR IF4G1 ... T106B APOE DKK1 VPS35 MBP SMAD4 NOTC3 BC11B HDAC4 ERBB4 BDNF CD24 CAN3 TNR6A WT1 ADNP GPC1 IL7RA FIG4 FCRL3 | 3.0635 | |
| GO:0009967 | 62 ABCA7 DNM1L GRB14 ANDR CFLAR PIBF1 PINK1 APOE CASPA TERA ... DKK1 VPS35 TFG SMAD4 CHC10 ERBB4 BDNF CD24 WWOX KHDR1 PLPL9 IL7RA HD FCRL3 SHAN3 PTPRC TEN1 A4 GRM1 PSN1 | 3.0442 | |
| GO:0098660 | 29 CACB4 ITPR1 KCNA1 AFG32 CAC1G SCN2A CAC1C TM175 CLCN2 SL9A1 ... CAC1D SL9A9 ATP7A S17A5 MPPB JPH3 AT1A3 SURF1 MPPA TRPV4 CAC1A TRPM7 KCND2 ATP7B PTPRC AT2B3 EAA1 KCNC3 PSN1 | 3.0434 | |
| GO:0061001 | 7 LRRK2 DNM1L PTEN ADA10 SHAN3 DREB NLGN3 | 3.0359 | |
| GO:0016079 | 7 SYT9 SYNJ1 DOC2B PCLO SYUA PSN1 VAMP1 | 3.0359 | |
| GO:900271 | 7 SQSTM SHAN3 APOE NEP A4 PRIO NLGN3 | 3.0359 | |
| GO:2001023 | 9 LRRK2 PINK1 MET GDNF PARK7 SYUA ARGI1 PRKN PSN1 | 3.0330 | |
| GO:0051881 | 9 LRRK2 PINK1 NDUS1 TAU PARK7 PANK2 TERA PRKN SODC | 3.0330 | |
| GO:0042982 | 5 ABCA7 ADA10 APOE PSN2 PSN1 | 3.0215 | |
| GO:0071625 | 5 SHAN2 SHAN3 NLGNX CNTP2 NLGN3 | 3.0215 | |
| GO:0009605 | 79 ABD12 VLDLR DNM1L DSRAD AFG32 GTR1 DEPD5 CFLAR IF4G1 APOE ... NPRL2 PURA1 RPC2 ROA1 SMAD4 BC11B OGT1 NPC2 SETD2 HDAC4 BDNF ELOV4 CD24 PPM1D TNR6A CNTP2 ADNP PLPL9 GPC1 HD | 3.0137 | |
| GO:0060024 | 3 EDN1 PTEN NLGN3 | 3.0137 | |
| GO:905908 | 3 APOE A4 PSN1 | 3.0137 | |
| GO:0021773 | 3 BC11B ZSWM6 SHAN3 | 3.0137 | |
| GO:0051348 | 18 UCHL1 AAKG2 DSRAD TAU ASM CAV3 FBX7 JIP1 PTEN APOE ... PARK7 NPRL2 GLCM PTPRC SORL PRKN RUBIC PSN1 | 2.9918 | |
| GO:0032386 | 24 SYT9 TADBP LRRK2 SETD2 KPCG ANK3 DNM1L HTRA2 KHDR1 AT132 ... DJC13 NFH CAC1D PINK1 HUWE1 PARK7 SUFU SORL TEN1 PRKN PRIO PSN1 VAMP1 FLNA | 2.9828 | |
| GO:0051646 | 7 UCHL1 LRRK2 DNM1L TAU BRAT1 TRAK2 MARK1 | 2.9799 | |
| GO:0043408 | 33 LRRK2 ABCA7 EDN1 NDRG2 SYGP1 ASM ANDR CAV3 CFLAR PINK1 ... JIP1 APOE GLCM SORL DKK1 SMAD4 PRKN SODC UCHL1 ERBB4 ULK4 PRDX2 CD24 PRDX1 TRPV4 PTEN FCRL3 PTPRC TEN1 A4 | 2.9710 | |
| GO:903827 | 28 LRRK2 ABCA7 ADA10 TAU ANDR CAV3 PINK1 HUWE1 CASP8 SORL ... VPS35 PRKN TTBK2 SQSTM TADBP SETD2 ERBB4 BDNF ANK3 HTRA2 AT132 NHLC1 PARK7 SUFU TEN1 PRIO PSN1 FLNA | 2.9710 | |
| GO:0090394 | 4 LRRK2 PTEN NLGNX NLGN3 | 2.9623 | |
| GO:0021953 | 14 BC11B ERBB4 TAU RORA GRID2 NKX62 ZSWM6 FEZF2 PTEN SHAN3 ... ATP7A GGYF2 SUFU PSN1 | 2.9227 | |
| GO:0090659 | 6 UCHL1 ABD12 HTRA2 DAB1 SPTCS NPC1 | 2.9191 | |
| GO:0099174 | 6 IF4G1 DKK1 VPS35 SYUA A4 NLGN3 | 2.9191 | |
| GO:0021756 | 5 BC11B LRRK2 ZSWM6 SHAN3 CNTP2 | 2.9153 | |
| GO:0043393 | 16 LRRK2 HDAC4 BDNF ADNP CHIP MET APOE PARK7 SORL DNJB2 ... DKK1 A4 PRKN TTBK2 TAF1 PSN1 | 2.9057 | |
| GO:0008088 | 8 KIF5A UCHL1 KIF1C TAU TRAK2 A4 SPTCS SODC | 2.9049 | |
| GO:0050768 | 18 NOTC3 LRRK2 ERBB4 DAB1 SYGP1 NKX62 TRPV4 NLGN3 FEZF2 PTEN ... APOE TRAK2 SEM5A SORL DKK1 A4 PSN1 IF4E | 2.8989 | |
| GO:901800 | 10 CHIP LRRK2 UBQL2 ATX3 GLCM DNJB2 TERA PRKN TAF1 PSN1 | 2.8904 | |
| GO:0007041 | 10 VPS53 PINK1 CI072 TRAK2 CHM2B SORL TERA VPS35 PRKN NPC1 | 2.8904 | |
| GO:2001234 | 16 LRRK2 BDNF PRDX2 GDNF NDUS3 HTRA2 ANDR CFLAR PINK1 JIP1 ... HD PARK7 CASP8 STRAB PRKN PSN1 | 2.8880 | |
| GO:0071496 | 20 LRRK2 HDAC4 DNM1L PPM1D TNR6A GTR1 DEPD5 SL9A1 ADNP IF4G1 ... TNR1A NPRL2 GLCM PTPRC CASP8 ROA1 CRADD NPRL3 TAF1 SODC | 2.8775 | |
| GO:902904 | 11 SPTN2 MET PROF1 SHAN3 APOE TBB4A SYUA SMAD4 CAV3 PRKN ... TTBK2 | 2.8775 | |
| GO:0007010 | 40 APCL SPTN2 DCTN1 ATX7 ATX3 TAU TBCE CAV3 MARK1 NFH ... CFLAR PIBF1 APOE MECP2 NPHP1 PCLO MYPN TTBK2 CE120 SODC ANGI SETD2 ULK4 WDR73 BACD1 SYNE1 ANK3 PROF1 ABI1 BICD2 | 2.8730 | |
| GO:0043254 | 23 SPTN2 DCTN1 PROF1 DNM1L TAU TF2H2 SYUA CAV3 IF4G1 CHIP ... PINK1 MET APOE PARK7 MECP2 GLCM TBB4A SORL TEN1 TERA DKK1 VPS35 MAGL2 | 2.8699 | |
| GO:0051341 | 10 LRRK2 EDN1 GDNF APOE PARK7 ATP7A SYUA CAV3 PRKN CHC10 | 2.8576 | |
| GO:0045595 | 66 VLDLR DNM1L ADA10 TAU SYGP1 ANDR FBX7 CFLAR IF4G1 T106B ... APOE DKK1 SMAD4 NOTC3 BC11B HDAC4 ERBB4 BDNF CD24 CAN3 TNR6A ADNP GPC1 IL7RA FIG4 FCRL3 SHAN3 CTDP1 TRAK2 PTPRC | 2.8535 | |
| GO:0071704 | 215 COQ2 ADA10 DSRAD S52A3 TYDP2 EXOS9 FBX7 CFLAR IF4G1 COQ7 ... CASPA RPC2 PSN2 CACP SMAD4 TTBK2 FRG1 SEN15 SMN UCHL1 ANGI SETD2 ERBB4 UBA5 ABI1 NEK1 SYMM XRCC1 NDUS6 CEP41 | 2.8504 | |
| GO:0043122 | 16 SQSTM TBK1 CAN3 RORA CCD22 OPTN CFLAR TNR1A LITAF PINK1 ... CASPA PPP5 CASP8 TFG PRKN FLNA | 2.8504 | |
| GO:0007204 | 16 ITPR1 EDN1 JPH3 CD24 CAC1C CAN3 TRPV4 SYUA CAV3 CAC1A ... SELT PLPL9 CAC1D HD PTPRC GRM1 | 2.8282 | |
| GO:903202 | 7 LRRK2 PINK1 MET PARK7 HTRA2 PRKN FBX7 | 2.8106 | |
| GO:900408 | 7 LRRK2 PINK1 MET PARK7 HTRA2 PRKN FBX7 | 2.8106 | |
| GO:0042987 | 4 ABCA7 ADA10 PSN2 PSN1 | 2.8011 | |
| GO:0045665 | 15 NOTC3 LRRK2 DAB1 SYGP1 TRPV4 NLGN3 FEZF2 PTEN APOE TRAK2 ... SEM5A DKK1 A4 PSN1 IF4E | 2.7914 | |
| GO:0031112 | 6 DCTN1 MET TAU MECP2 TRPV4 CAV3 | 2.7787 | |
| GO:0008361 | 13 BDNF EDN1 TAU XK TRPV4 CAV3 ADNP IL7RA PTEN SHAN3 ... APOE ATP7A SEM5A | 2.7759 | |
| GO:0034220 | 36 CACB4 ITPR1 AAKG2 KCNA1 AFG32 CAC1G S6A19 SCN2A CAC1C TM175 ... CLCN2 SL9A1 CAC1D SL9A9 ATP7A SC6A8 S17A5 MPPB JPH3 AT1A3 SURF1 MPPA AT132 GRID2 S35A3 TRPV4 CAC1A ANO10 TRPM7 KCND2 | 2.7698 | |
| GO:0097164 | 14 ASAH1 SC5A7 ASM SYUA PLPL6 PLPL9 MECP2 SNCAP ATP7A GLCM ... CACP TY3H PRKN TMLH | 2.7656 | |
| GO:0042552 | 10 GPC1 MYP0 SCN8A FIG4 PTEN AFG32 XK SCN2A NKX62 SODC | 2.7560 | |
| GO:0010720 | 27 EDN1 VLDLR DNM1L TAU NKX62 CFLAR IF4G1 FEZF2 T106B APOE ... SETX DKK1 PRKN BDNF DAB1 ADNP FIG4 PTEN SHAN3 NEUS SEM5A NEP DREB FBX38 A4 PSN1 FLNA | 2.7557 | |
| GO:0051235 | 12 BSCL2 PINK1 SYNE1 ANK3 APOE ATP7B PARK7 DREB SORL CCD22 ... GPAA1 FLNA | 2.7283 | |
| GO:0044057 | 29 CACB4 LRRK2 ITPR1 EDN1 KCNA1 CAC1G CAC1C CAV3 SL9A1 CAC1D ... MECP2 NLGNX GLCM SMAD4 SODC HDAC4 AT1A3 NLGN3 TNR1A FIG4 PTEN SHAN3 KCND2 CTDP1 TY3H AT2B3 A4 GRM1 FLNA | 2.7283 | |
| GO:0016242 | 6 LRRK2 PINK1 HTRA2 RUBIC UBQL4 NPC1 | 2.7097 | |
| GO:0032388 | 15 SYT9 TADBP ANK3 DNM1L HTRA2 KHDR1 CAC1D PINK1 HUWE1 SORL ... TEN1 PRKN PRIO PSN1 FLNA | 2.7076 | |
| GO:0034605 | 7 CHIP ATX3 TAU S52A3 HTRA2 TERA TRPV4 | 2.7076 | |
| GO:902883 | 7 LRRK2 PINK1 MET PARK7 HTRA2 PRKN FBX7 | 2.7076 | |
| GO:0031113 | 7 DCTN1 MET TAU MECP2 TBB4A SYUA CAV3 | 2.7076 | |
| GO:0048168 | 7 JPH3 SHAN3 APOE SYGP1 DREB SYUA A4 | 2.7076 | |
| GO:0099111 | 12 KIF5A UCHL1 KIF1C HD TAU IF140 BICD2 TRAK2 A4 ARL3 ... SPTCS SODC | 2.7076 | |
| GO:0010970 | 12 KIF5A UCHL1 KIF1C HD TAU IF140 BICD2 TRAK2 A4 ARL3 ... SPTCS SODC | 2.7076 | |
| GO:0010507 | 9 IF4G1 LRRK2 PINK1 MET HTRA2 SYUA RUBIC UBQL4 NPC1 | 2.6886 | |
| GO:903363 | 9 OGT1 KPCG PARK7 FHIT SUFU AT132 VPS35 TAF1 PSN1 | 2.6886 | |
| GO:0046916 | 9 FRIL ATP7B ATP7A AT132 A4 CCD22 SMAD4 PRIO SODC | 2.6886 | |
| GO:903201 | 8 LRRK2 PINK1 MET PARK7 HTRA2 PRKN FBX7 SODC | 2.6886 | |
| GO:901299 | 3 PINK1 MET PARK7 | 2.6855 | |
| GO:902956 | 3 PINK1 PARK7 SYUA | 2.6855 | |
| GO:903377 | 3 PINK1 PARK7 PRKN | 2.6855 | |
| GO:0044089 | 26 DCTN1 EDN1 TAU CAV3 IF4G1 PINK1 MET MECP2 ATP7A NPHP1 ... TERA CE120 HDAC4 BDNF PROF1 TF2H2 AT132 GRID2 NLGN3 ADNP CHIP AUTS2 HD TEN1 MAGL2 FLNA | 2.6825 | |
| GO:0007154 | 147 MKS1 SYT9 ABCA7 DCTN1 VLDLR DNM1L ADA10 DSRAD GRB14 TAU ... SCN2A TYDP2 GTR1 DEPD5 IF4G1 AGRG2 DAPLE PINK1 CASPA PSN2 ROA1 DKK1 VPS35 MBP SMAD4 TTBK2 UCHL1 ANGI HDAC4 MYP0 | 2.6694 | |
| GO:902430 | 4 ABCA7 APOE SORL PRIO | 2.6694 | |
| GO:0001963 | 4 PARK7 TY3H SYUA PRKN | 2.6694 | |
| GO:0010960 | 4 KCNA1 ANK3 TRPM7 XK | 2.6694 | |
| GO:904925 | 4 PINK1 GLCM OPTN PRKN | 2.6694 | |
| GO:0071257 | 4 PTEN PURA1 GRM1 SL9A1 | 2.6694 | |
| GO:0043409 | 13 UCHL1 NDRG2 ASM CAV3 PINK1 JIP1 PTEN APOE GLCM PTPRC ... SORL SMAD4 PRKN | 2.6694 | |
| GO:902115 | 14 LRRK2 EDN1 CHM2B GRID2 CAV3 UBQL2 PINK1 CI072 HD ATG5 ... IF140 SMAD4 CE120 CHM1A | 2.6686 | |
| GO:0050773 | 12 LRRK2 VLDLR DNM1L PTEN ADA10 SHAN3 T106B APOE DREB MARK1 ... PSN1 NLGN3 | 2.6674 | |
| GO:0034599 | 16 LRRK2 PRDX2 TAU HTRA2 PRDX1 AT132 SYUA CFLAR SGMR1 PINK1 ... SETX PARK7 ATP7A PPP5 ARGI1 SODC | 2.6674 | |
| GO:0010959 | 21 CACB4 FGF14 FHL1 KCNA1 JPH3 ANK3 CAC1C CAN3 SYUA CAV3 ... SL9A1 PLPL9 CAC1D HD PTEN FCRL3 ATG5 ATP7A PSN2 PRIO FLNA | 2.6672 | |
| GO:0097237 | 15 PRDX2 SELT SGMR1 PINK1 PTEN APOE SETX PARK7 ATP7A PPP5 ... TY3H ROA1 ARGI1 PRKN SODC | 2.6638 | |
| GO:902003 | 5 ABCA7 APOE SORL A4 PRIO | 2.6508 | |
| GO:0051347 | 30 LRRK2 EDN1 AAKG2 VLDLR TAU PIBF1 PINK1 ALS2 PNKP STRAB ... SORL DKK1 SODC ANGI BDNF PRDX2 CD24 ABI1 DAB1 SYUA ADNP CHIP PTEN PARK7 PTPRC TEN1 GRM1 PRIO PI3R5 PSN1 | 2.6386 | |
| GO:0033157 | 16 TADBP LRRK2 SETD2 ANK3 HTRA2 AT132 PINK1 HUWE1 PARK7 SUFU ... SORL TEN1 PRKN PRIO PSN1 FLNA | 2.6290 | |
| GO:903530 | 33 SYT9 LRRK2 ITPR1 EDN1 KPCG DNM1L CAC1C GTR1 CAC1D PINK1 ... NDUF2 ATG5 APOE PCLO VPS35 MBP SMAD4 PRKN VAMP1 TADBP ANGI GDNF FOXP1 AT132 FRM4A TRPV4 SYUA CAC1A SELT PLPL9 | 2.6083 | |
| GO:0021587 | 6 XRCC1 SPTN2 ATP7A DAB1 RORA GRID2 | 2.5968 | |
| GO:0001666 | 20 ANGI ITPR1 EDN1 DNM1L CD24 SCN2A RORA GTR1 SL9A1 CFLAR ... XRCC1 CHIP PINK1 PTEN KCND2 MECP2 ATP7A PSN2 TY3H SMAD4 | 2.5920 | |
| GO:0006816 | 16 CACB4 ITPR1 MPPB JPH3 DNM1L AFG32 CAC1G MPPA CAC1C TRPV4 ... CAC1A CAC1D TRPM7 PTPRC AT2B3 PSN1 | 2.5901 | |
| GO:0051650 | 14 KIF5A SYT9 TM230 KIF1C SYNJ1 SYUA TBC23 HD DOC2B PCLO ... TFG PSN1 SPTCS VAMP1 | 2.5823 | |
| GO:0035637 | 11 CACB4 CAC1D KCNA1 ANK3 AT1A3 KCND2 CAC1G CAC1C CNTP2 SL9A1 ... SODC | 2.5717 | |
| GO:0002082 | 5 PINK1 PARK7 ATP7A TERA SYUA | 2.5625 | |
| GO:0010256 | 20 SQSTM TADBP LRRK2 ABCA7 DCTN1 REEP3 SYNE1 ANK3 VAPB CHM2B ... OPTN DJC13 CAV3 VRK1 ALS2 HD PTEN PTPRC SODC CHM1A | 2.5625 | |
| GO:0051480 | 17 ITPR1 EDN1 JPH3 CD24 CAC1C CAN3 TRPV4 SYUA CAV3 CAC1A ... SELT PLPL9 CAC1D HD PTPRC AT2B3 GRM1 | 2.5562 | |
| GO:0055076 | 10 FRIL ATP7B ATP7A AT132 A4 CCD22 SMAD4 PRKN PRIO SODC | 2.5501 | |
| GO:0007034 | 10 VPS53 PINK1 CI072 TRAK2 CHM2B SORL TERA VPS35 PRKN NPC1 | 2.5501 | |
| GO:0009635 | 4 HTRA2 TY3H ROA1 ARGI1 | 2.5426 | |
| GO:0051937 | 4 PARK7 MECP2 SYUA PRKN | 2.5426 | |
| GO:0021535 | 4 DAB1 RERE TTBK2 FLNA | 2.5426 | |
| GO:0031223 | 4 HD SHAN3 EAA1 CNTP2 | 2.5426 | |
| GO:0010976 | 17 BDNF VLDLR DNM1L TAU ADNP CFLAR FIG4 SHAN3 T106B APOE ... SETX NEUS SEM5A DREB FBX38 PRKN PSN1 | 2.5249 | |
| GO:0051493 | 25 SPTN2 DCTN1 EDN1 TAU CHM2B CAV3 SL9A1 MET MECP2 SMAD4 ... PRKN TTBK2 CE120 PROF1 BICD2 TRPV4 SYUA CI072 SHAN3 SEM5A TBB4A TEN1 MAGL2 FLNA CHM1A | 2.5249 | |
| GO:0051353 | 7 EDN1 GDNF APOE PARK7 ATP7A SYUA CHC10 | 2.5249 | |
| GO:0010823 | 7 LRRK2 OMA1 PINK1 DNM1L TAU HTRA2 PRKN | 2.5249 | |
| GO:0070997 | 7 LRRK2 ATN1 SIAH1 SCN2A A4 SL9A1 PSN1 | 2.5249 | |
| GO:0042177 | 11 OGT1 KPCG PARK7 FHIT SUFU AT132 VPS35 SYUA TAF1 PSN1 ... FLNA | 2.5248 | |
| GO:0042692 | 15 FLNC UCHL1 SYNE1 AFG32 XK ACTS CAN3 RORA WT1 CAV3 ... SL9A1 CFLAR ATG5 MECP2 MYPN | 2.5078 | |
| GO:0023061 | 12 SELT SYT9 EDN1 SC5A7 PARK7 SYNJ1 DOC2B PCLO TRPV4 SYUA ... PSN1 VAMP1 | 2.4961 | |
| GO:0045185 | 9 PINK1 SYNE1 ANK3 PARK7 DREB SORL CCD22 GPAA1 FLNA | 2.4928 | |
| GO:0042181 | 5 COQ2 COQ9 COQ7 COQ8A DLP1 | 2.4902 | |
| GO:905809 | 5 PTEN APOE DKK1 PRIO NLGN3 | 2.4902 | |
| GO:0021680 | 5 SPTN2 ATP7A RORA ANAG RERE | 2.4902 | |
| GO:0051590 | 6 SYT9 CAC1D DNM1L SYUA PRKN PSN1 | 2.4852 | |
| GO:0070482 | 21 ANGI ITPR1 EDN1 DNM1L DPOG1 CD24 SCN2A RORA GTR1 SL9A1 ... CFLAR XRCC1 CHIP PINK1 PTEN KCND2 MECP2 ATP7A PSN2 TY3H SMAD4 | 2.4699 | |
| GO:0098693 | 10 SYT9 FGF14 LRRK2 CAC1D KPCG DNM1L PTEN SYUA VAMP1 NLGN3 | 2.4678 | |
| GO:0032411 | 10 FGF14 PINK1 KCNA1 ANK3 HD SHAN3 PARK7 CHC10 SL9A1 NLGN3 | 2.4678 | |
| GO:0060078 | 9 FGF14 LRRK2 KCNA1 KCND2 MECP2 GRID2 SYUA GRM1 NLGN3 | 2.4626 | |
| GO:0097435 | 20 ANGI WDR73 BACD1 TAU ABI1 ACTS CAN3 TRPV4 SYUA LUM ... CAV3 NFH CFLAR ATP7A DREB A4 MYPN MAGL2 CE120 FLNA | 2.4548 | |
| GO:0050770 | 12 BDNF FEZF2 PTEN APOE TAU DAB1 TRAK2 SYGP1 XK SEM5A ... PSN1 ADNP | 2.4548 | |
| GO:2001236 | 12 CFLAR PRDX2 HD PTEN GDNF PARK7 HTRA2 WWOX PTPRC CASP8 ... STRAB ANDR | 2.4548 | |
| GO:0030705 | 12 KIF5A UCHL1 KIF1C HD TAU IF140 BICD2 TRAK2 A4 ARL3 ... SPTCS SODC | 2.4548 | |
| GO:0070507 | 13 DCTN1 TAU BICD2 CHM2B TRPV4 SYUA CAV3 MET MECP2 TBB4A ... TTBK2 CE120 CHM1A | 2.4548 | |
| GO:0051716 | 174 MKS1 ABCA7 DCTN1 ASAH1 VLDLR DNM1L ADA10 DSRAD GRB14 TAU ... S52A3 SCN2A TYDP2 GTR1 DEPD5 CFLAR IF4G1 AGRG2 DAPLE PINK1 CARTF CASPA PSN2 ROA1 DKK1 VPS35 MBP SMAD4 TTBK2 S12A6 | 2.4541 | |
| GO:0010637 | 3 OMA1 DNM1L PRKN | 2.4493 | |
| GO:0036293 | 20 ANGI ITPR1 EDN1 DNM1L CD24 SCN2A RORA GTR1 SL9A1 CFLAR ... XRCC1 CHIP PINK1 PTEN KCND2 MECP2 ATP7A PSN2 TY3H SMAD4 | 2.4427 | |
| GO:0017156 | 7 SYT9 SYNJ1 DOC2B PCLO SYUA PSN1 VAMP1 | 2.4394 | |
| GO:0099558 | 4 DCTN1 SYGP1 PCLO CHC10 | 2.4326 | |
| GO:902992 | 4 ABCA7 APOE SORL PRIO | 2.4326 | |
| GO:0034764 | 14 FGF14 KCNA1 ANK3 CAN3 SYUA SL9A1 NLGN3 PINK1 HD SHAN3 ... PARK7 CHC10 PSN1 FLNA | 2.4320 | |
| GO:0021544 | 5 BC11B LRRK2 ZSWM6 SHAN3 CNTP2 | 2.4205 | |
| GO:0031645 | 5 LRRK2 FIG4 PTEN NLGNX NLGN3 | 2.4205 | |
| GO:0055002 | 10 CFLAR FLNC UCHL1 ATG5 AFG32 XK ACTS CAN3 MYPN CAV3 | 2.4171 | |
| GO:0051588 | 11 SYT9 LRRK2 CAC1D KPCG DNM1L GDNF SNCAP SYUA PRKN PSN1 ... VAMP1 | 2.4013 | |
| GO:0048584 | 78 ABCA7 KPCG DNM1L ADA10 GRB14 ATX3 ANDR CFLAR PIBF1 PINK1 ... APOE CASPA RPC2 TERA DKK1 VPS35 TFG SMAD4 CHC10 ERBB4 BDNF CD24 ABI1 WWOX KHDR1 CAN3 XRCC1 PLPL9 IL7RA HD | 2.3945 | |
| GO:0051648 | 14 KIF5A SYT9 TM230 KIF1C SYNJ1 SYUA TBC23 HD DOC2B PCLO ... TFG PSN1 SPTCS VAMP1 | 2.3922 | |
| GO:0006928 | 52 VLDLR GRB14 TAU RERE IF140 BRAT1 FAT2 SMAD4 TTBK2 SPTCS ... BC11B UCHL1 ANGI SETD2 ERBB4 BDNF BACD1 CD24 GPC1 HD SHAN3 TRAK2 PTPRC A4 OLR1 PSN1 FLNA KIF5A LRRK2 SPTN2 | 2.3881 | |
| GO:0021575 | 6 XRCC1 SPTN2 ATP7A DAB1 RORA GRID2 | 2.3791 | |
| GO:0032535 | 19 SPTN2 BDNF EDN1 PROF1 TAU XK AT132 TRPV4 CAV3 ADNP ... IL7RA ALS2 PTEN SHAN3 APOE ATP7A SEM5A TEN1 MAGL2 | 2.3700 | |
| GO:0051651 | 8 PINK1 SYNE1 ANK3 APOE PARK7 DREB SORL GPAA1 | 2.3556 | |
| GO:0021537 | 16 BC11B LRRK2 ERBB4 KCNA1 DAB1 GTR1 CNTP2 XRCC1 ZSWM6 FEZF2 ... PTEN SHAN3 TY3H CE120 PSN1 FLNA | 2.3537 | |
| GO:0080171 | 7 LRRK2 TPP1 GLCM TM175 ANAG VPS35 SPTCS | 2.3532 | |
| GO:0007040 | 7 LRRK2 TPP1 GLCM TM175 ANAG VPS35 SPTCS | 2.3532 | |
| GO:0042417 | 5 SNCAP ATP7A TY3H SYUA PRKN | 2.3505 | |
| GO:902175 | 5 PINK1 PARK7 HTRA2 PRKN SODC | 2.3505 | |
| GO:2001024 | 5 LRRK2 PINK1 MET PARK7 SYUA | 2.3505 | |
| GO:0010996 | 5 ABD12 HD SHAN3 EAA1 CNTP2 | 2.3505 | |
| GO:901360 | 100 VLDLR DSRAD TAU ODP2 S52A3 TPK1 TYDP2 EXOS9 IF4G1 RPC2 ... ROA1 SMAD4 FRG1 SEN15 NPC1 BC11B SMN ANGI SETD2 ELOV4 HNRH2 TF2H2 SYMM XRCC1 SNCAP SEN54 A4 RL10 LRRK2 FUS | 2.3408 | |
| GO:0010977 | 11 LRRK2 PTEN APOE DAB1 TRAK2 SYGP1 SEM5A TRPV4 DKK1 PSN1 ... NLGN3 | 2.3292 | |
| GO:0034063 | 4 ATX2 RS23 CI072 TAU | 2.3270 | |
| GO:0007638 | 4 HD SHAN3 EAA1 CNTP2 | 2.3270 | |
| GO:0009991 | 25 LRRK2 OMA1 DNM1L S6A19 GTR1 DEPD5 IF4G1 APOE NPRL2 GLCM ... PURA1 ROA1 SODC OGT1 PPM1D ACTS TNR6A TRPV4 ADNP PTEN PTPRC TY3H ARGI1 NPRL3 TAF1 | 2.3128 | |
| GO:0032886 | 14 DCTN1 TAU BICD2 CHM2B TRPV4 SYUA CAV3 NFH MET MECP2 ... TBB4A TTBK2 CE120 CHM1A | 2.2969 | |
| GO:901379 | 8 CAC1D FHL1 KCNA1 ANK3 PTEN CAV3 PRIO FLNA | 2.2876 | |
| GO:900407 | 8 LRRK2 PINK1 MET PARK7 HTRA2 PRKN FBX7 SODC | 2.2876 | |
| GO:0031644 | 11 LRRK2 EDN1 FIG4 PTEN SHAN3 NLGNX GLCM A4 GRM1 SL9A1 ... NLGN3 | 2.2796 | |
| GO:901661 | 5 COQ2 COQ9 COQ7 COQ8A DLP1 | 2.2794 | |
| GO:0098815 | 6 LRRK2 PTEN SHAN3 NLGNX A4 NLGN3 | 2.2760 | |
| GO:0032507 | 7 PINK1 SYNE1 ANK3 PARK7 DREB SORL GPAA1 | 2.2714 | |
| GO:0048638 | 18 ERBB4 BDNF EDN1 TAU AFG32 HTRA2 CAN3 WT1 ANDR CAV3 ... ADNP PTEN APOE CTDP1 SEM5A A4 PRKN SODC | 2.2714 | |
| GO:0016236 | 11 SQSTM SNX14 AAKG2 PINK1 ATG5 GLCM CHM2B AT132 TERA PRKN ... PSN1 | 2.2576 | |
| GO:0045860 | 25 LRRK2 EDN1 AAKG2 VLDLR PIBF1 PINK1 ALS2 STRAB DKK1 SODC ... ANGI BDNF PRDX2 CD24 ABI1 DAB1 SYUA ADNP PARK7 PTPRC TEN1 GRM1 PRIO PI3R5 PSN1 | 2.2576 | |
| GO:0071900 | 24 UCHL1 LRRK2 EDN1 AAKG2 PRDX2 CD24 ASM SYUA CAV3 FBX7 ... JIP1 ALS2 HD PTEN APOE GLCM PTPRC SORL TEN1 DKK1 GRM1 PI3R5 PSN1 SODC | 2.2576 | |
| GO:0098596 | 3 HD SHAN3 CNTP2 | 2.2576 | |
| GO:0090494 | 3 PARK7 SYUA PRKN | 2.2576 | |
| GO:0042297 | 3 HD SHAN3 CNTP2 | 2.2576 | |
| GO:0034205 | 3 ABCA7 ADA10 PSN1 | 2.2576 | |
| GO:0034392 | 3 EDN1 DIA1 DNMT1 | 2.2576 | |
| GO:0050882 | 3 XRCC1 ITPR1 VPS35 | 2.2576 | |
| GO:0035333 | 3 ADA10 PSN2 PSN1 | 2.2576 | |
| GO:905446 | 3 PINK1 PARK7 SYUA | 2.2576 | |
| GO:0070841 | 3 TAU TERA PRKN | 2.2576 | |
| GO:0031345 | 12 LRRK2 PTEN APOE DAB1 TRAK2 SYGP1 SEM5A TRPV4 DKK1 PRIO ... PSN1 NLGN3 | 2.2416 | |
| GO:0034641 | 103 ABCA7 ASAH1 ADA10 DSRAD TAU ODP2 S52A3 TPK1 TYDP2 EXOS9 ... IF4G1 RPC2 CACP ROA1 SMAD4 FRG1 SEN15 BC11B SMN ANGI SETD2 ELOV4 HNRH2 TF2H2 SYMM XRCC1 SEN54 A4 RL10 TMLH | 2.2354 | |
| GO:903008 | 6 SQSTM VRK1 PINK1 TERA PRKN FBX7 | 2.2354 | |
| GO:901032 | 4 LRRK2 PINK1 MET PARK7 | 2.2354 | |
| GO:2001039 | 4 LRRK2 PINK1 MET PARK7 | 2.2354 | |
| GO:903206 | 4 LRRK2 PINK1 MET PARK7 | 2.2354 | |
| GO:0090083 | 4 SNCAP SORL DNJB2 SACS | 2.2354 | |
| GO:0097711 | 9 MKS1 B9D2 DCTN1 TBA4A NPHP1 TBB4A CEP41 B9D1 TTBK2 | 2.2336 | |
| GO:902803 | 8 SYT9 LRRK2 CAC1D KPCG PINK1 DNM1L PRKN VAMP1 | 2.2328 | |
| GO:0007269 | 8 SYT9 SC5A7 SYNJ1 DOC2B PCLO SYUA PSN1 VAMP1 | 2.2328 | |
| GO:901615 | 22 NPC2 COQ2 ASAH1 AAKG2 VLDLR SYNJ1 ASM SYUA CP4V2 ACON ... PTEN APOE PARK7 MECP2 SNCAP ATP7A GLCM TY3H SORL A4 PRKN NPC1 | 2.2328 | |
| GO:0006629 | 45 ABD12 OMA1 COQ2 BSCL2 ASAH1 EDN1 PIGG AAKG2 VLDLR VAPB ... ASM PLD3 CAV3 APOE MECP2 GLCM CACP SORL EFR3A NPC1 NPC2 ANGI ELOV4 HTRA2 WWOX SYNJ1 SYUA PLPL6 PLPL9 GPC1 | 2.2307 | |
| GO:0051100 | 12 CHIP LRRK2 CI072 MET PARK7 SORL DNJB2 DKK1 TTBK2 TAF1 ... PSN1 ADNP | 2.2307 | |
| GO:902991 | 5 ABCA7 APOE SORL A4 PRIO | 2.2307 | |
| GO:0043457 | 5 PINK1 PARK7 TERA TRPV4 SYUA | 2.2307 | |
| GO:0031116 | 5 DCTN1 MET TAU MECP2 CAV3 | 2.2307 | |
| GO:0007628 | 5 UCHL1 ABD12 HTRA2 DAB1 NPC1 | 2.2307 | |
| GO:0090066 | 23 LRRK2 SPTN2 BDNF EDN1 PROF1 TAU XK AT132 TRPV4 CAV3 ... ADNP PLPL9 IL7RA ALS2 PTEN ATG5 SHAN3 APOE ATP7A SEM5A TEN1 MAGL2 SODC | 2.2094 | |
| GO:0046928 | 9 SYT9 LRRK2 CAC1D KPCG DNM1L SNCAP SYUA PRKN VAMP1 | 2.2094 | |
| GO:0099643 | 8 SYT9 SC5A7 SYNJ1 DOC2B PCLO SYUA PSN1 VAMP1 | 2.2027 | |
| GO:0034248 | 20 ANGI ABCA7 KHDR1 TNR6A SYUA SELT PLPL9 IF4G1 ATX2 TNR1A ... PINK1 APOE GGYF2 SORL A4 RL10 SPCS PRIO IF4E PUM1 | 2.2027 | |
| GO:0044238 | 201 COQ2 ADA10 DSRAD TYDP2 EXOS9 FBX7 CFLAR IF4G1 CASPA RPC2 ... PSN2 CACP SMAD4 TTBK2 FRG1 SEN15 SMN UCHL1 ANGI SETD2 ERBB4 UBA5 ABI1 NEK1 SYMM XRCC1 NDUS6 CEP41 OLR1 LRRK2 | 2.1839 | |
| GO:2000331 | 2 VPS35 NLGN3 | 2.1839 | |
| GO:0042539 | 2 TRPV4 S12A6 | 2.1839 | |
| GO:2000468 | 2 LRRK2 SYUA | 2.1839 | |
| GO:0010273 | 2 PARK7 ATP7A | 2.1839 | |
| GO:902823 | 2 LRRK2 VPS35 | 2.1839 | |
| GO:902954 | 2 SORL DJC13 | 2.1839 | |
| GO:903181 | 2 PARK7 VPS35 | 2.1839 | |
| GO:903179 | 2 PARK7 VPS35 | 2.1839 | |
| GO:903336 | 2 LRRK2 VPS35 | 2.1839 | |
| GO:903384 | 2 PINK1 PARK7 | 2.1839 | |
| GO:903383 | 2 PINK1 PARK7 | 2.1839 | |
| GO:903852 | 2 PINK1 CHC10 | 2.1839 | |
| GO:903850 | 2 PINK1 CHC10 | 2.1839 | |
| GO:0071477 | 2 TRPV4 S12A6 | 2.1839 | |
| GO:990169 | 2 PARK7 ATP7A | 2.1839 | |
| GO:0051604 | 13 OGT1 OMA1 ADA10 AFG32 HTRA2 MPPA CHIP ATP7B PSN2 CASP8 ... NEP SORL PSN1 | 2.1795 | |
| GO:0006469 | 14 UCHL1 AAKG2 DSRAD ASM CAV3 FBX7 JIP1 PTEN APOE PARK7 ... GLCM PTPRC SORL PSN1 | 2.1775 | |
| GO:905606 | 5 IF4G1 DKK1 VPS35 SYUA A4 | 2.1763 | |
| GO:0032414 | 9 FGF14 PINK1 KCNA1 ANK3 HD SHAN3 CHC10 SL9A1 NLGN3 | 2.1620 | |
| GO:0033674 | 26 LRRK2 EDN1 AAKG2 VLDLR TAU PIBF1 PINK1 ALS2 STRAB DKK1 ... SODC ANGI BDNF PRDX2 CD24 ABI1 DAB1 SYUA ADNP PARK7 PTPRC TEN1 GRM1 PRIO PI3R5 PSN1 | 2.1614 | |
| GO:2000726 | 4 CTDP1 DKK1 SMAD4 CAV3 | 2.1581 | |
| GO:0071280 | 4 ATP7A SYUA A4 PRIO | 2.1581 | |
| GO:0051046 | 33 SYT9 LRRK2 ITPR1 EDN1 KPCG DNM1L CAC1C GTR1 CAC1D PINK1 ... NDUF2 ATG5 APOE PCLO VPS35 MBP SMAD4 PRKN VAMP1 TADBP ANGI GDNF FOXP1 AT132 FRM4A TRPV4 SYUA CAC1A SELT PLPL9 | 2.1574 | |
| GO:0051494 | 10 SPTN2 MET PROF1 SHAN3 TBB4A SYUA SMAD4 CAV3 PRKN TTBK2 | 2.1547 | |
| GO:0051924 | 15 CACB4 FGF14 JPH3 CAC1C CAN3 SYUA CAV3 SL9A1 PLPL9 CAC1D ... HD FCRL3 ATG5 PSN2 PRIO | 2.1172 | |
| GO:0071709 | 5 ANK3 PTEN NLGNX CAV3 NLGN3 | 2.1122 | |
| GO:0000226 | 20 APCL SETD2 DCTN1 ULK4 WDR73 ATX7 ATX3 TAU TBCE BICD2 ... TRPV4 CAV3 MARK1 NFH PIBF1 HD MECP2 TTBK2 CE120 FLNA | 2.1115 | |
| GO:0098597 | 3 HD SHAN3 CNTP2 | 2.1115 | |
| GO:0090493 | 3 PARK7 SYUA PRKN | 2.1115 | |
| GO:0098779 | 3 PINK1 OPTN PRKN | 2.1115 | |
| GO:903376 | 3 PINK1 PARK7 PRKN | 2.1115 | |
| GO:903862 | 3 PINK1 PARK7 TERA | 2.1115 | |
| GO:905165 | 3 GLCM AT132 VPS35 | 2.1115 | |
| GO:905906 | 3 APOE A4 PSN1 | 2.1115 | |
| GO:0021932 | 3 DAB1 RERE FLNA | 2.1115 | |
| GO:0071472 | 3 CAN3 TRPV4 S12A6 | 2.1115 | |
| GO:0097105 | 3 PTEN NLGNX NLGN3 | 2.1115 | |
| GO:0048312 | 3 LRRK2 DNM1L TAU | 2.1115 | |
| GO:0098657 | 23 LRRK2 VLDLR MYO1E DNM1L REPS1 AT1A3 TF2H2 RBG1L SYNJ1 SYUA ... CAV3 SL9A1 NLGN3 AUXI CI072 APOE PARK7 SORL EAA1 A4 PRKN RUBIC NPC1 | 2.1115 | |
| GO:0000302 | 13 EDN1 PRDX2 APTX TAU CFLAR SGMR1 APOE SETX PARK7 ATP7A ... PPP5 ARGI1 SODC | 2.1115 | |
| GO:0070585 | 7 LRRK2 PINK1 DNM1L MPPA PRKN TIM14 FBX7 | 2.1102 | |
| GO:0010467 | 65 ADA10 DSRAD AFG32 ATX1 EXOS9 ANDR IF4G1 SYRM SYDM RPC2 ... PSN2 ROA1 SMAD4 FRG1 SEN15 NOTC3 SMN OGT1 ANGI SETD2 HNRH2 TF2H2 PPM1D KHDR1 SYAM WT1 SYMM CTDP1 SEN54 A4 | 2.1099 | |
| GO:0043467 | 11 OGT1 PPR3F HDAC4 AAKG2 PINK1 PARK7 ATP7A TERA TRPV4 SYUA ... CHC10 | 2.1092 | |
| GO:0060047 | 8 CAC1D DNM1L ATG5 CAC1G CAC1C CAV3 SL9A1 SODC | 2.0918 | |
| GO:0032091 | 9 CHIP LRRK2 MET PARK7 SORL DNJB2 DKK1 TTBK2 ADNP | 2.0882 | |
| GO:0055001 | 10 CFLAR FLNC UCHL1 ATG5 AFG32 XK ACTS CAN3 MYPN CAV3 | 2.0882 | |
| GO:0016125 | 10 NPC2 CP4V2 AAKG2 VLDLR APOE GLCM SORL ASM A4 NPC1 | 2.0882 | |
| GO:0048193 | 17 KIF5A NBAS SPTN2 DCTN1 KIF1C ANK3 BICD2 VAPB CCD22 OPTN ... ARL3 VP13C HD SCYL1 SORL TERA TFG | 2.0866 | |
| GO:0050435 | 4 ABCA7 ADA10 NEP PSN1 | 2.0813 | |
| GO:902176 | 4 PINK1 PARK7 HTRA2 PRKN | 2.0813 | |
| GO:0010644 | 4 KCNA1 AT1A3 CAC1C DREB | 2.0813 | |
| GO:0006515 | 4 CHIP OMA1 ATX3 TERA | 2.0813 | |
| GO:0043405 | 18 UCHL1 LRRK2 EDN1 PRDX2 CD24 ASM CAV3 JIP1 APOE GLCM ... PTPRC SORL TEN1 DKK1 GRM1 PI3R5 PSN1 SODC | 2.0813 | |
| GO:0051438 | 6 CHIP PINK1 DNM1L PTEN PARK7 PSN1 | 2.0769 | |
| GO:0021517 | 6 DCTN1 VLDLR GGYF2 DAB1 SUFU NKX62 | 2.0769 | |
| GO:0031122 | 5 WDR73 TAU TRPV4 CAV3 CE120 | 2.0678 | |
| GO:0010942 | 30 LRRK2 DNM1L ADA10 TAU SIAH1 ASM SL9A1 IF4G1 PINK1 PSN2 ... CASP8 TERA DKK1 CHC10 SODC SQSTM HDAC4 HTRA2 WWOX UNC5C SYUA PLPL9 TNR1A HD PTEN PARK7 PTPRC CRADD PRIO PSN1 | 2.0562 | |
| GO:0035556 | 52 ITPR1 CAH8 SYGP1 SCN2A DEPD5 DAPLE PINK1 APOE PSN2 MBP ... SMAD4 OGT1 HDAC4 ERBB4 CD24 PPM1D WWOX ADNP SHAN3 PTPRC PSN1 LRRK2 SPTN2 EDN1 AAKG2 RGPS2 CAC1C TBK1 ARL3 MARK1 | 2.0521 | |
| GO:0045596 | 30 LRRK2 SYGP1 RORA NKX62 CAV3 FBX7 CFLAR FEZF2 APOE MECP2 ... SORL DKK1 SMAD4 DNMT1 NOTC3 HDAC4 ERBB4 BDNF PRDX2 DAB1 TRPV4 NLGN3 PTEN CTDP1 TRAK2 SEM5A SUFU A4 PSN1 IF4E | 2.0473 | |
| GO:0070838 | 16 CACB4 ITPR1 MPPB JPH3 DNM1L AFG32 CAC1G MPPA CAC1C TRPV4 ... CAC1A CAC1D TRPM7 PTPRC AT2B3 PSN1 | 2.0448 | |
| GO:0009108 | 10 COQ2 ELOV4 COQ9 ODP2 COQ7 TPK1 ELOV5 PANK2 COQ8A DLP1 | 2.0448 | |
| GO:0071901 | 10 UCHL1 AAKG2 JIP1 PTEN APOE GLCM SORL ASM CAV3 FBX7 | 2.0448 | |
| GO:0051963 | 9 IF4G1 BDNF GRID2 DKK1 VPS35 SYUA A4 NLGN3 ADNP | 2.0396 | |
| GO:902882 | 8 LRRK2 PINK1 MET PARK7 HTRA2 PRKN FBX7 SODC | 2.0373 | |
| GO:0031668 | 15 LRRK2 DNM1L PPM1D TNR6A GTR1 DEPD5 ADNP IF4G1 NPRL2 GLCM ... PTPRC ROA1 NPRL3 TAF1 SODC | 2.0373 | |
| GO:2000059 | 6 OGT1 PARK7 FHIT SUFU TAF1 PSN1 | 2.0347 | |
| GO:0070207 | 5 SGMR1 ATX10 HTRA2 ARGI1 SMAD4 | 2.0124 | |
| GO:0055026 | 5 PTEN CTDP1 DKK1 SMAD4 CAV3 | 2.0124 | |
| GO:0048675 | 5 AUTS2 RAPH1 CI072 SPTCS NLGN3 | 2.0124 | |
| GO:0051146 | 12 CFLAR FLNC UCHL1 ATG5 AFG32 XK ACTS CAN3 MYPN WT1 ... CAV3 SL9A1 | 2.0103 | |
| GO:0006807 | 188 ABD12 ABCA7 ASAH1 VLDLR ADA10 DSRAD TAU ODP2 S52A3 TPK1 ... TYDP2 EXOS9 FBX7 CFLAR IF4G1 PINK1 CASPA RPC2 PSN2 SCYL1 CACP ROA1 MBP SMAD4 TTBK2 FRG1 SEN15 NPC1 BC11B SMN | 2.0097 | |
| GO:0016239 | 7 PINK1 CI072 HD VP13D TBK1 OPTN PRKN | 2.0097 | |
| GO:0007568 | 16 LRRK2 EDN1 DPOG1 HTRA2 SYUA NDUS6 LITAF PTEN TY3H NEP ... DKK1 A4 ARGI1 PRIO PSN1 SODC | 2.0053 | |
| GO:904951 | 22 TADBP LRRK2 ANGI ANK3 DNM1L HTRA2 AT132 FRM4A TRPV4 PLPL9 ... PINK1 HUWE1 CASP8 DOC2B SORL TEN1 VPS35 MBP PRIO CE120 PSN1 FLNA | 2.0053 | |
| GO:0000422 | 4 SQSTM PINK1 PRKN FBX7 | 2.0053 | |
| GO:0051580 | 4 GDNF SYUA PRKN PSN1 | 2.0053 | |
| GO:0061726 | 4 SQSTM PINK1 PRKN FBX7 | 2.0053 | |
| GO:0034614 | 10 CFLAR SGMR1 PRDX2 TAU SETX PARK7 ATP7A PPP5 ARGI1 SODC | 2.0038 | |
| GO:903322 | 10 CHIP LRRK2 HDAC4 PINK1 PTEN HUWE1 AMER1 TERA NHLC1 PRKN | 2.0038 | |
| GO:0015696 | 6 EDN1 PARK7 SC6A8 SYUA PRKN PSN1 | 1.9963 | |
| GO:0043123 | 12 CFLAR TNR1A LITAF PINK1 CASPA PPP5 CASP8 TBK1 TFG CCD22 ... PRKN FLNA | 1.9963 | |
| GO:0072384 | 7 KIF5A UCHL1 KIF1C HD TAU BICD2 TRAK2 | 1.9819 | |
| GO:0072511 | 16 CACB4 ITPR1 MPPB JPH3 DNM1L AFG32 CAC1G MPPA CAC1C TRPV4 ... CAC1A CAC1D TRPM7 PTPRC AT2B3 PSN1 | 1.9819 | |
| GO:901298 | 3 PINK1 MET PARK7 | 1.9819 | |
| GO:2000302 | 3 SYT9 CAC1D DNM1L | 1.9819 | |
| GO:0010635 | 3 OMA1 DNM1L PRKN | 1.9819 | |
| GO:0010835 | 3 XRCC1 PNKP ADNP | 1.9819 | |
| GO:0043653 | 3 ERBB4 DNM1L VPS35 | 1.9819 | |
| GO:0097090 | 3 PTEN NLGNX NLGN3 | 1.9819 | |
| GO:0016082 | 3 SYNJ1 SYUA VAMP1 | 1.9819 | |
| GO:2001235 | 12 PLPL9 PINK1 DNM1L PTEN SIAH1 PARK7 HTRA2 WWOX PTPRC CASP8 ... CHC10 SODC | 1.9817 | |
| GO:0050790 | 72 APCL VLDLR DNM1L DSRAD TAU SYGP1 DEPD5 FBX7 CFLAR PIBF1 ... PINK1 APOE NPRL2 PSN2 STRAB DNJB2 TERA DKK1 MBP CHC10 TIM14 UCHL1 PPR3F ANGI BDNF TF2H2 CD24 ABI1 AT132 CAN3 | 1.9804 | |
| GO:0051093 | 37 LRRK2 OMA1 DNM1L TAU SYGP1 RORA NKX62 CAV3 FBX7 CFLAR ... PINK1 FEZF2 APOE MECP2 SORL DKK1 SMAD4 PRKN DNMT1 NOTC3 HDAC4 ERBB4 BDNF PRDX2 DAB1 TRPV4 WT1 NLGN3 FIG4 PTEN | 1.9791 | |
| GO:0044249 | 85 COQ2 ASAH1 DPOG1 ODP2 TPK1 GTR1 ANDR IF4G1 SYRM SYDM ... APOE COQ7 PURA1 RPC2 TERA SMAD4 NPC1 NOTC3 SMN OGT1 ANGI SETD2 ELOV4 BACD1 SC5A7 TF2H2 PPM1D SYAM NHLC1 SYMM | 1.9724 | |
| GO:0016485 | 10 OGT1 OMA1 ADA10 AFG32 HTRA2 MPPA PSN2 CASP8 NEP PSN1 | 1.9629 | |
| GO:0098900 | 6 ANK3 GLCM CAC1C CAV3 SL9A1 FLNA | 1.9609 | |
| GO:0051966 | 6 PLPL9 LRRK2 SHAN3 DKK1 PSN1 NLGN3 | 1.9609 | |
| GO:0021879 | 6 BC11B ERBB4 ZSWM6 FEZF2 SHAN3 ATP7A | 1.9609 | |
| GO:0043068 | 28 LRRK2 DNM1L ADA10 TAU SIAH1 ASM SL9A1 PINK1 PSN2 CASP8 ... TERA CHC10 SODC SQSTM HDAC4 HTRA2 WWOX UNC5C SYUA PLPL9 TNR1A HD PTEN PARK7 PTPRC CRADD PRIO PSN1 | 1.9555 | |
| GO:2001259 | 7 FGF14 PINK1 KCNA1 ANK3 HD SHAN3 NLGN3 | 1.9527 | |
| GO:0043407 | 7 UCHL1 JIP1 APOE GLCM SORL ASM CAV3 | 1.9527 | |
| GO:903051 | 7 OGT1 KPCG PARK7 FHIT SUFU TAF1 PSN1 | 1.9527 | |
| GO:0051495 | 13 DCTN1 EDN1 PROF1 TAU TRPV4 CAV3 MET MECP2 SEM5A TEN1 ... MAGL2 CE120 FLNA | 1.9518 | |
| GO:0023052 | 139 MKS1 CACB4 SYT9 ABCA7 DCTN1 VLDLR DNM1L ADA10 DSRAD GRB14 ... TAU SCN2A TYDP2 DEPD5 AGRG2 DAPLE PINK1 CASPA PSN2 ROA1 DKK1 VPS35 MBP SMAD4 TTBK2 HDAC4 MYP0 ERBB4 BDNF ANK3 | 1.9518 | |
| GO:0042053 | 4 PARK7 VPS35 SYUA PRKN | 1.9406 | |
| GO:0042069 | 4 PARK7 VPS35 SYUA PRKN | 1.9406 | |
| GO:0070584 | 4 NDUS6 DNM1L PANK2 NUBPL | 1.9406 | |
| GO:0014059 | 4 PINK1 GDNF SYUA PRKN | 1.9406 | |
| GO:0031579 | 4 ABCA7 PTPRC CAV3 NPC1 | 1.9406 | |
| GO:0015844 | 4 PARK7 MECP2 SYUA PRKN | 1.9406 | |
| GO:0035690 | 18 LRRK2 EDN1 CFLAR SGMR1 PINK1 PTEN SETX PARK7 PURA1 PPP5 ... TY3H ROA1 ARGI1 PRKN PRIO TAF1 IF4E SODC | 1.9406 | |
| GO:0002791 | 23 SYT9 TADBP LRRK2 ANGI ITPR1 DNM1L FOXP1 CAC1C AT132 FRM4A ... GTR1 TRPV4 CAC1A SELT PLPL9 CAC1D NDUF2 ATG5 APOE DOC2B VPS35 MBP PRKN | 1.9397 | |
| GO:0010629 | 56 ATN1 VLDLR DSRAD TAU ATX1 EXOS9 ANDR IF4G1 PINK1 APOE ... GGYF2 DKK1 VPS35 SMAD4 NOTC3 ANGI HDAC4 PPM1D WWOX KHDR1 CAN3 TNR6A WT1 ADNP A4 RL10 PSN1 FLNA LRRK2 EDN1 | 1.9397 | |
| GO:903578 | 9 OGT1 HDAC4 AAKG2 PINK1 DNM1L PARK7 ATP7A TERA SYUA | 1.9294 | |
| GO:0060271 | 17 MKS1 B9D2 DCTN1 ATX10 ARMC9 NEK1 B9D1 ARL3 TM237 PIBF1 ... IF140 TBA4A NPHP1 TBB4A CEP41 TTBK2 FLNA | 1.9275 | |
| GO:0050771 | 6 PTEN DAB1 TRAK2 SYGP1 SEM5A PSN1 | 1.9267 | |
| GO:0071470 | 5 SCN2A CAN3 GTR1 TRPV4 S12A6 | 1.9248 | |
| GO:0071868 | 5 LRRK2 SYUA A4 PRKN SL9A1 | 1.9248 | |
| GO:0071870 | 5 LRRK2 SYUA A4 PRKN SL9A1 | 1.9248 | |
| GO:0050708 | 22 SYT9 TADBP LRRK2 ANGI ITPR1 DNM1L FOXP1 CAC1C AT132 FRM4A ... GTR1 TRPV4 CAC1A PLPL9 CAC1D NDUF2 ATG5 APOE DOC2B VPS35 MBP PRKN | 1.9218 | |
| GO:0031323 | 168 ABCA7 VLDLR DNM1L DSRAD TAU TYDP2 EXOS9 RERE FBX7 CFLAR ... IF4G1 DAPLE RB39B PINK1 CARTF STRAB ROA1 DNJB2 DKK1 VPS35 MBP SMAD4 NPC1 BC11B UCHL1 PPR3F ANGI SETD2 HDAC4 ERBB4 | 1.9114 | |
| GO:0043266 | 8 CAC1D FHL1 KCNA1 ANK3 PTEN CAV3 PRIO FLNA | 1.9114 | |
| GO:900006 | 7 VLDLR DNM1L SHAN3 T106B APOE DREB PSN1 | 1.8915 | |
| GO:0050885 | 6 JPH3 GGYF2 TPP1 NKX62 EAA1 A4 | 1.8870 | |
| GO:0000278 | 27 DCTN1 REEP3 TBCE PHF8 CHM2B OPTN ARL3 POGZ VRK1 PIBF1 ... MECP2 GGYF2 CAD13 SETD2 ANK3 PPM1D KHDR1 HD TBA4A CTDP1 PPP5 TBB4A CEP41 CRADD IF4E FLNA CHM1A | 1.8870 | |
| GO:0009408 | 8 CHIP ATX3 TAU S52A3 HTRA2 TERA TRPV4 SODC | 1.8823 | |
| GO:0044091 | 5 ANK3 PTEN NLGNX CAV3 NLGN3 | 1.8726 | |
| GO:0003156 | 5 MKS1 GDNF DKK1 WT1 ANDR | 1.8726 | |
| GO:0001956 | 4 SYT9 CAC1D DNM1L SYUA | 1.8711 | |
| GO:903204 | 4 PINK1 PARK7 PRKN FBX7 | 1.8711 | |
| GO:905208 | 4 CTDP1 DKK1 SMAD4 CAV3 | 1.8711 | |
| GO:903047 | 25 DCTN1 REEP3 TBCE PHF8 CHM2B OPTN ARL3 POGZ VRK1 PIBF1 ... MECP2 GGYF2 SETD2 ANK3 PPM1D KHDR1 HD TBA4A CTDP1 TBB4A CEP41 CRADD IF4E FLNA CHM1A | 1.8699 | |
| GO:0000012 | 3 XRCC1 TYDP1 APTX | 1.8699 | |
| GO:0098598 | 3 HD SHAN3 CNTP2 | 1.8699 | |
| GO:0042415 | 3 ATP7A TY3H PRKN | 1.8699 | |
| GO:902805 | 3 SYT9 CAC1D DNM1L | 1.8699 | |
| GO:0019430 | 3 PRDX2 ATP7A SODC | 1.8699 | |
| GO:904350 | 3 GLCM AT132 VPS35 | 1.8699 | |
| GO:0045760 | 3 ANK3 GLCM SL9A1 | 1.8699 | |
| GO:0007220 | 3 ADA10 PSN2 PSN1 | 1.8699 | |
| GO:0015872 | 3 PARK7 SYUA PRKN | 1.8699 | |
| GO:0019752 | 34 EDN1 AAKG2 ODP2 HUTU GTR1 SL9A1 SYRM SYDM MECP2 ATP7A ... SC6A8 PURA1 CACP PANK2 L2HDH NPC1 ELOV4 SYAM SYUA SYMM NDUS6 TNR1A CP4V2 ACON DGLA PARK7 BCKD MYPR TY3H ELOV5 | 1.8697 | |
| GO:0051259 | 24 SQSTM FUS ATX10 KCNA1 BACD1 DNM1L TAU HTRA2 KHDR1 SYUA ... ANDR SL9A1 DAPLE SGMR1 TRPM7 KCND2 PPP5 CXB1 TERA KCNC3 ARGI1 SMAD4 PRIO DLP1 | 1.8697 | |
| GO:0007411 | 13 BC11B SPTN2 BDNF VLDLR GDNF SIAH1 DAB1 UNC5C GPC1 FEZF2 ... SHAN3 A4 SMAD4 | 1.8637 | |
| GO:0051668 | 8 SHAN3 APOE CD24 SYGP1 PTPRC VPS35 CAD13 FLNA | 1.8637 | |
| GO:0051098 | 19 LRRK2 HDAC4 BDNF ADNP IF4G1 CHIP CI072 MET APOE PARK7 ... SORL DNJB2 DKK1 A4 SMAD4 PRKN TTBK2 TAF1 PSN1 | 1.8593 | |
| GO:0007632 | 6 MECP2 SYGP1 NPHP1 HXA1 A4 NLGN3 | 1.8575 | |
| GO:2001257 | 11 CACB4 PLPL9 FGF14 PINK1 KCNA1 JPH3 ANK3 HD SHAN3 A4 ... NLGN3 | 1.8529 | |
| GO:0006839 | 12 AAKG2 PINK1 AFG32 MPPA CASP8 VPS35 PRKN CHC10 TIM14 SL9A1 ... PSN1 FBX7 | 1.8529 | |
| GO:0032273 | 9 DCTN1 PINK1 MET PROF1 TAU MECP2 TEN1 CAV3 MAGL2 | 1.8426 | |
| GO:903747 | 7 LRRK2 PINK1 TAU HUWE1 HTRA2 CASP8 PRKN | 1.8379 | |
| GO:0061351 | 7 KCNA1 DGLA RORA DREB RERE CE120 SOX5 | 1.8379 | |
| GO:0045597 | 37 EDN1 VLDLR DNM1L TAU NKX62 ANDR CAV3 SOX5 CFLAR IF4G1 ... FEZF2 T106B APOE SETX CASP8 DKK1 SMAD4 PRKN BDNF GDNF CD24 DAB1 ADNP GPC1 IL7RA FIG4 PTEN SHAN3 NEUS PTPRC | 1.8348 | |
| GO:0042136 | 5 DGLA SC5A7 TY3H RORA EAA1 | 1.8348 | |
| GO:2000725 | 5 EDN1 CTDP1 DKK1 SMAD4 CAV3 | 1.8348 | |
| GO:904646 | 5 AT1A3 A4 PRIO CAC1A PSN1 | 1.8348 | |
| GO:0097485 | 13 BC11B SPTN2 BDNF VLDLR GDNF SIAH1 DAB1 UNC5C GPC1 FEZF2 ... SHAN3 A4 SMAD4 | 1.8339 | |
| GO:901016 | 6 CAC1D FHL1 KCNA1 ANK3 PTEN CAV3 | 1.8276 | |
| GO:903829 | 17 SQSTM TADBP ABCA7 ERBB4 ANK3 TAU HTRA2 PINK1 HUWE1 PARK7 ... CASP8 SORL TEN1 PRKN PRIO PSN1 FLNA | 1.8276 | |
| GO:0044255 | 35 ABD12 COQ2 ASAH1 EDN1 PIGG AAKG2 VAPB ASM CAV3 APOE ... MECP2 GLCM CACP EFR3A ANGI ELOV4 HTRA2 SYNJ1 SYUA PLPL6 PLPL9 GPC1 NDUS6 TNR1A CP4V2 DGLA FIG4 PTEN MYPR TY3H | 1.8276 | |
| GO:0090258 | 2 PINK1 TAU | 1.8276 | |
| GO:0042414 | 2 ATP7A TY3H | 1.8276 | |
| GO:902958 | 2 PINK1 PARK7 | 1.8276 | |
| GO:902995 | 2 ABCA7 APOE | 1.8276 | |
| GO:902994 | 2 ABCA7 APOE | 1.8276 | |
| GO:0010836 | 2 XRCC1 PNKP | 1.8276 | |
| GO:0060003 | 2 ATP7B ATP7A | 1.8276 | |
| GO:903751 | 2 PINK1 PARK7 | 1.8276 | |
| GO:903750 | 2 PINK1 PARK7 | 1.8276 | |
| GO:905289 | 2 LRRK2 HD | 1.8276 | |
| GO:0070495 | 2 MET SYUA | 1.8276 | |
| GO:0070494 | 2 MET SYUA | 1.8276 | |
| GO:0023021 | 2 GLCM ASM | 1.8276 | |
| GO:0015677 | 2 ATP7B ATP7A | 1.8276 | |
| GO:0044070 | 8 PLPL9 ABCA7 EDN1 APOE SYUA ARGI1 PRIO PSN1 | 1.8239 | |
| GO:0033344 | 4 NPC2 ABCA7 APOE NPC1 | 1.8239 | |
| GO:0051654 | 4 UCHL1 TAU TRAK2 MARK1 | 1.8239 | |
| GO:903205 | 4 LRRK2 PINK1 MET PARK7 | 1.8239 | |
| GO:0045956 | 4 SYT9 CAC1D DNM1L DOC2B | 1.8239 | |
| GO:900273 | 4 SQSTM SHAN3 NEP A4 | 1.8239 | |
| GO:0051222 | 20 TADBP LRRK2 ANGI ANK3 DNM1L HTRA2 AT132 FRM4A TRPV4 PLPL9 ... PINK1 HUWE1 DOC2B SORL TEN1 VPS35 MBP PRIO PSN1 FLNA | 1.8195 | |
| GO:0065007 | 302 MKS1 DCTN1 ADA10 DSRAD GRB14 SCN2A TYDP2 EXOS9 RERE DEPD5 ... FBX7 CFLAR IF4G1 AGRG2 DAPLE RB39B SCN3A T106B CASPA RPC2 PSN2 DKK1 VPS35 TFG SMAD4 TTBK2 TIM14 UCHL1 PPR3F ANGI | 1.8195 | |
| GO:0030307 | 11 IF4G1 BDNF EDN1 ADA10 TAU BRAT1 SEM5A EXOS9 PRKN SL9A1 ... ADNP | 1.8093 | |
| GO:0031667 | 22 OGT1 LRRK2 OMA1 DNM1L PPM1D S6A19 TNR6A GTR1 TRPV4 DEPD5 ... IF4G1 PTEN APOE NPRL2 GLCM PURA1 TY3H ROA1 ARGI1 NPRL3 TAF1 SODC | 1.8058 | |
| GO:0031056 | 10 SETD5 OGT1 LRRK2 AUTS2 PINK1 ATG5 MECP2 SYUA SMAD4 DNMT1 | 1.8009 | |
| GO:0019226 | 5 KCNA1 ANK3 KCND2 CNTP2 SODC | 1.8009 | |
| GO:0060291 | 5 SHAN2 PTEN MECP2 SYUA NLGN3 | 1.8009 | |
| GO:0050848 | 8 LRRK2 ITPR1 JPH3 HD TAU PRIO CAD13 SL9A1 | 1.8009 | |
| GO:0003015 | 8 CAC1D DNM1L ATG5 CAC1G CAC1C CAV3 SL9A1 SODC | 1.8009 | |
| GO:0032092 | 8 LRRK2 BDNF APOE PARK7 A4 PRKN TAF1 PSN1 | 1.8009 | |
| GO:0032271 | 12 SPTN2 DCTN1 PINK1 MET PROF1 TAU MECP2 TBB4A TEN1 SYUA ... CAV3 MAGL2 | 1.7994 | |
| GO:0044782 | 17 MKS1 B9D2 DCTN1 ATX10 ARMC9 NEK1 B9D1 ARL3 TM237 PIBF1 ... IF140 TBA4A NPHP1 TBB4A CEP41 TTBK2 FLNA | 1.7982 | |
| GO:0022604 | 21 LRRK2 BDNF DNM1L ADA10 TAU DAB1 SYGP1 XK CF410 NLGN3 ... ADNP FEZF2 PTEN SHAN3 APOE TRAK2 SEM5A DREB PRKN PSN1 FLNA | 1.7861 | |
| GO:0019222 | 178 ABCA7 ASAH1 VLDLR DNM1L DSRAD TAU TYDP2 EXOS9 RERE FBX7 ... CFLAR IF4G1 DAPLE RB39B PINK1 CARTF STRAB ROA1 DNJB2 DKK1 VPS35 MBP SMAD4 NPC1 BC11B UCHL1 PPR3F ANGI SETD2 HDAC4 | 1.7809 | |
| GO:0008016 | 14 CACB4 HDAC4 ITPR1 EDN1 AT1A3 CAC1G CAC1C CAV3 SL9A1 CAC1D ... KCND2 TY3H AT2B3 FLNA | 1.7793 | |
| GO:0098810 | 3 PARK7 SYUA PRKN | 1.7756 | |
| GO:902950 | 3 APOE VPS35 PRIO | 1.7756 | |
| GO:0090084 | 3 SORL DNJB2 SACS | 1.7756 | |
| GO:0031669 | 13 LRRK2 DNM1L PPM1D TNR6A GTR1 DEPD5 IF4G1 NPRL2 GLCM ROA1 ... NPRL3 TAF1 SODC | 1.7691 | |
| GO:0071236 | 9 SGMR1 PTEN SETX PARK7 ATP7A PPP5 ROA1 ARGI1 SL9A1 | 1.7691 | |
| GO:0006997 | 9 VRK1 TADBP DCTN1 REEP3 WDR73 ATX7 SYNE1 CHM2B CHM1A | 1.7691 | |
| GO:0017157 | 12 SYT9 PLPL9 LRRK2 CAC1D KPCG DNM1L DOC2B PCLO AT132 SYUA ... PRKN VAMP1 | 1.7673 | |
| GO:0019233 | 7 UCHL1 EDN1 KCNA1 KCND2 MECP2 NEP GRM1 | 1.7673 | |
| GO:0140238 | 4 AUXI DNM1L SYNJ1 SYUA | 1.7673 | |
| GO:0009651 | 4 TY3H CAN3 TRPV4 S12A6 | 1.7673 | |
| GO:0001504 | 4 PARK7 EAA1 SYUA PRKN | 1.7673 | |
| GO:0010288 | 4 TAU ATP7A PPP5 A4 | 1.7673 | |
| GO:0048488 | 4 AUXI DNM1L SYNJ1 SYUA | 1.7673 | |
| GO:0032232 | 4 MET PROF1 SHAN3 PRKN | 1.7673 | |
| GO:0043065 | 27 DNM1L ADA10 TAU SIAH1 ASM SL9A1 PINK1 PSN2 CASP8 TERA ... CHC10 SODC SQSTM HDAC4 HTRA2 WWOX UNC5C SYUA PLPL9 TNR1A HD PTEN PARK7 PTPRC CRADD PRIO PSN1 | 1.7673 | |
| GO:0071867 | 5 LRRK2 SYUA A4 PRKN SL9A1 | 1.7624 | |
| GO:0071869 | 5 LRRK2 SYUA A4 PRKN SL9A1 | 1.7624 | |
| GO:0040008 | 28 EDN1 ADA10 NDUS3 TAU AFG32 EXOS9 ANDR CAV3 SL9A1 IF4G1 ... APOE BRAT1 DNJB2 SMAD4 PRKN SODC SQSTM ERBB4 BDNF FHL1 HTRA2 CAN3 WT1 ADNP PTEN CTDP1 SEM5A A4 | 1.7575 | |
| GO:0030100 | 12 AUXI ATX2 LRRK2 ABCA7 UBQL2 DNM1L APOE DKK1 SYUA CAV3 ... CAD13 RUBIC | 1.7550 | |
| GO:0031333 | 9 SPTN2 PROF1 PARK7 GLCM TBB4A SORL DKK1 VPS35 SYUA | 1.7519 | |
| GO:902275 | 11 SETD5 OGT1 LRRK2 AUTS2 PINK1 ATG5 MECP2 PHF8 SYUA SMAD4 ... DNMT1 | 1.7448 | |
| GO:0051047 | 20 SYT9 TADBP LRRK2 ANGI EDN1 DNM1L GDNF AT132 FRM4A TRPV4 ... SYUA SELT PLPL9 CAC1D PINK1 ATG5 DOC2B VPS35 MBP SMAD4 | 1.7403 | |
| GO:0010611 | 6 TNR1A EDN1 CTDP1 SMAD4 CAV3 SL9A1 | 1.7342 | |
| GO:903532 | 19 SYT9 TADBP LRRK2 ANGI EDN1 DNM1L GDNF AT132 FRM4A TRPV4 ... SYUA SELT PLPL9 CAC1D PINK1 DOC2B VPS35 MBP SMAD4 | 1.7328 | |
| GO:0016458 | 9 CLP1 DSRAD MECP2 PPM1D GGYF2 TNR6A DNMT1 PUM1 CHM1A | 1.7302 | |
| GO:0072359 | 33 MKS1 EDN1 MYO1E LAMA1 CAC1C RORA CAV3 SL9A1 NDUV2 ATG5 ... APOE IF140 ATP7A HXA1 SMAD4 CAD13 S12A6 NOTC3 ANGI SETD2 ERBB4 DIA1 B9D1 WT1 NDUS6 TNR1A PTEN SEM5A SUFU MATR3 | 1.7302 | |
| GO:0140056 | 10 MKS1 B9D2 DCTN1 TBA4A PSN2 NPHP1 TBB4A CEP41 B9D1 TTBK2 | 1.7302 | |
| GO:0071548 | 5 CFLAR EDN1 GLCM ARGI1 IF4E | 1.7185 | |
| GO:0031062 | 5 OGT1 AUTS2 MECP2 SMAD4 DNMT1 | 1.7185 | |
| GO:0030029 | 22 ANGI MYO1E BACD1 PROF1 ATX3 CAC1G ABI1 ACTS CAC1C CAN3 ... TRPV4 CAV3 SL9A1 CFLAR AUTS2 CAC1D TRPM7 NPHP1 DREB MYPN MAGL2 FLNA | 1.7147 | |
| GO:0021543 | 11 XRCC1 KCNA1 FEZF2 PTEN DAB1 TY3H GTR1 CNTP2 CE120 PSN1 ... FLNA | 1.7102 | |
| GO:902652 | 9 NPC2 ACON VLDLR APOE GLCM SORL ASM A4 NPC1 | 1.7102 | |
| GO:0051153 | 8 CFLAR HDAC4 BDNF EDN1 CTDP1 DKK1 SMAD4 CAV3 | 1.7102 | |
| GO:2001237 | 8 CFLAR PRDX2 HD GDNF PARK7 CASP8 STRAB ANDR | 1.7102 | |
| GO:0051354 | 4 LRRK2 SYUA CAV3 PRKN | 1.7102 | |
| GO:903421 | 4 FGF14 LRRK2 DNM1L SYUA | 1.7102 | |
| GO:903649 | 4 LRRK2 SORL DJC13 PRKN | 1.7102 | |
| GO:0048512 | 4 PTEN KCND2 TY3H ANAG | 1.7102 | |
| GO:0043244 | 8 SPTN2 SETX GLCM SEM5A TRPV4 TTBK2 RUBIC UBQL4 | 1.6835 | |
| GO:904861 | 3 PTEN SHAN3 GRID2 | 1.6833 | |
| GO:0045475 | 3 PTEN KCND2 ANAG | 1.6833 | |
| GO:0071451 | 3 PRDX2 ATP7A SODC | 1.6833 | |
| GO:0071450 | 3 PRDX2 ATP7A SODC | 1.6833 | |
| GO:0048143 | 3 TAU A4 PSN1 | 1.6833 | |
| GO:900272 | 3 APOE A4 PRIO | 1.6833 | |
| GO:0046677 | 16 EDN1 APTX SL9A1 IF4G1 SGMR1 PTEN SETX PARK7 ATP7A PPP5 ... CASP8 TY3H ROA1 EAA1 ARGI1 SODC | 1.6759 | |
| GO:0050796 | 11 SYT9 PLPL9 TADBP CAC1D ITPR1 NDUF2 CAC1C DOC2B GTR1 PRKN ... CAC1A | 1.6584 | |
| GO:0010771 | 7 PTEN DAB1 TRAK2 SYGP1 SEM5A PSN1 NLGN3 | 1.6579 | |
| GO:0080090 | 161 ABCA7 ASAH1 VLDLR DNM1L DSRAD TAU TYDP2 EXOS9 RERE FBX7 ... CFLAR IF4G1 DAPLE PINK1 CARTF STRAB ROA1 DNJB2 DKK1 VPS35 MBP SMAD4 BC11B UCHL1 PPR3F ANGI SETD2 HDAC4 ERBB4 BDNF | 1.6553 | |
| GO:0031334 | 13 DCTN1 PROF1 TAU TF2H2 CAV3 IF4G1 CHIP PINK1 MET MECP2 ... TEN1 TERA MAGL2 | 1.6553 | |
| GO:2001038 | 4 LRRK2 PINK1 MET PARK7 | 1.6524 | |
| GO:0035640 | 4 LRRK2 JPH3 ATX3 APOE | 1.6524 | |
| GO:0048169 | 4 SHAN3 SYGP1 SYUA A4 | 1.6524 | |
| GO:0007622 | 4 PTEN KCND2 TY3H ANAG | 1.6524 | |
| GO:0080134 | 51 ABD12 KPCG DSRAD ATX3 TAU TBC23 FBX7 IF4G1 PINK1 APOE ... RPC2 DKK1 VPS35 SETD2 CAN3 CHCH2 XRCC1 FCRL3 PTPRC A4 LRRK2 EDN1 FUS TBK1 RORA OPTN CAV3 UBQL2 JIP1 MET | 1.6524 | |
| GO:0050896 | 217 MKS1 DCTN1 ADA10 DSRAD GRB14 S52A3 SCN2A TYDP2 EXOS9 DEPD5 ... CFLAR IF4G1 AGRG2 DAPLE CASPA RPC2 PSN2 DKK1 VPS35 SMAD4 TTBK2 UCHL1 ANGI SETD2 ERBB4 BDNF ANK3 NDUAC AT1A3 CD24 | 1.6477 | |
| GO:0034976 | 13 TADBP DCTN1 ITPR1 ATX3 UBA5 VAPB NHLC1 PLPL9 CHIP UBQL2 ... TPP1 TERA PRKN | 1.6423 | |
| GO:0009058 | 87 COQ2 ASAH1 DPOG1 ODP2 TPK1 GTR1 ANDR IF4G1 SYRM SYDM ... APOE COQ7 PURA1 RPC2 TERA SMAD4 NPC1 NOTC3 SMN OGT1 ANGI SETD2 ELOV4 BACD1 SC5A7 TF2H2 PPM1D SYAM NHLC1 SYMM | 1.6418 | |
| GO:0001558 | 19 BDNF FHL1 EDN1 ADA10 NDUS3 TAU EXOS9 WT1 CAV3 SL9A1 ... ADNP IF4G1 APOE CTDP1 BRAT1 SEM5A DNJB2 SMAD4 PRKN | 1.6418 | |
| GO:0014743 | 6 TNR1A EDN1 CTDP1 SMAD4 CAV3 SL9A1 | 1.6418 | |
| GO:0060255 | 164 ABCA7 VLDLR DNM1L DSRAD TAU TYDP2 EXOS9 RERE FBX7 CFLAR ... IF4G1 DAPLE PINK1 CARTF STRAB ROA1 DNJB2 DKK1 VPS35 MBP SMAD4 BC11B UCHL1 PPR3F ANGI SETD2 HDAC4 ERBB4 BDNF ANK3 | 1.6418 | |
| GO:0009712 | 5 SNCAP ATP7A TY3H SYUA PRKN | 1.6418 | |
| GO:0060999 | 5 DNM1L SHAN3 APOE DREB PSN1 | 1.6418 | |
| GO:0061005 | 5 MYO1E GDNF CD24 AMER1 WT1 | 1.6418 | |
| GO:0006584 | 5 SNCAP ATP7A TY3H SYUA PRKN | 1.6418 | |
| GO:0043603 | 29 ABCA7 ASAH1 ADA10 ODP2 HUTU ASM FMT IF4G1 SYRM SYDM ... GLCM PANK2 SODC ELOV4 HTRA2 ORNT1 SYAM SYMM SELT RS23 PARK7 TPP1 ELOV5 NEP ARGI1 RL10 SPCS PSN1 IF4E | 1.6388 | |
| GO:0055024 | 7 ERBB4 EDN1 PTEN CTDP1 DKK1 SMAD4 CAV3 | 1.6373 | |
| GO:0044092 | 40 LRRK2 AAKG2 DSRAD TAU ASM CCD22 CAV3 FBX7 CFLAR JIP1 ... MET APOE NPRL2 ATP7A GLCM CASP8 SORL DNJB2 DKK1 PRKN TTBK2 UCHL1 HDAC4 PRDX2 ANK3 SYUA ADNP CHIP CI072 PTEN | 1.6276 | |
| GO:0050793 | 79 MKS1 VLDLR DNM1L ADA10 TAU AFG32 SYGP1 ANDR FBX7 CFLAR ... IF4G1 PINK1 T106B APOE DKK1 VPS35 MBP SMAD4 NOTC3 BC11B HDAC4 ERBB4 BDNF CD24 CAN3 TNR6A WT1 ADNP GPC1 IL7RA | 1.6276 | |
| GO:0045927 | 14 ERBB4 BDNF EDN1 ADA10 TAU CAN3 EXOS9 WT1 SL9A1 ADNP ... IF4G1 BRAT1 SEM5A PRKN | 1.6088 | |
| GO:0110110 | 7 CFLAR EDN1 GDNF DKK1 WT1 SMAD4 ANDR | 1.6086 | |
| GO:0090316 | 10 TADBP PINK1 ANK3 HUWE1 HTRA2 SORL TEN1 PRIO PSN1 FLNA | 1.6048 | |
| GO:2001239 | 5 PRDX2 GDNF HTRA2 WWOX STRAB | 1.6048 | |
| GO:0035307 | 5 PINK1 FCRL3 GLCM PTPRC ASM | 1.6048 | |
| GO:0043954 | 5 DCTN1 SYGP1 PCLO CHC10 PRIO | 1.6048 | |
| GO:0086003 | 5 CAC1D CAC1G CAC1C CAV3 SL9A1 | 1.6048 | |
| GO:0001941 | 4 GDNF SHAN3 APOE NLGN3 | 1.6048 | |
| GO:0010614 | 4 TNR1A CTDP1 SMAD4 CAV3 | 1.6048 | |
| GO:0035020 | 3 OGT1 AUTS2 ALS2 | 1.6048 | |
| GO:0021692 | 3 SPTN2 ATP7A RORA | 1.6048 | |
| GO:0048311 | 3 LRRK2 DNM1L TAU | 1.6048 | |
| GO:0008104 | 60 ABCA7 VLDLR DNM1L ATX3 SYGP1 FBX7 PIBF1 PINK1 APOE IF140 ... CACP STRAB TERA VPS35 CHC10 TIM14 NPC1 SYNE1 ANK3 CD24 CAN3 CNTP2 SHAN3 DOC2B CEP41 DREB PAHX RL10 GPAA1 PSN1 | 1.6048 | |
| GO:901097 | 2 RUBIC UBQL4 | 1.6048 | |
| GO:2000152 | 2 PARK7 TERA | 1.6048 | |
| GO:0001514 | 2 SELT SPCS | 1.6048 | |
| GO:2000825 | 2 PARK7 TAF1 | 1.6048 | |
| GO:0035022 | 2 AUTS2 ALS2 | 1.6048 | |
| GO:0002265 | 2 A4 PSN1 | 1.6048 | |
| GO:902822 | 2 LRRK2 VPS35 | 1.6048 | |
| GO:903121 | 2 PTEN PARK7 | 1.6048 | |
| GO:904351 | 2 AT132 VPS35 | 1.6048 | |
| GO:0061687 | 2 PARK7 ATP7A | 1.6048 | |
| GO:904978 | 2 SYNJ1 PRKN | 1.6048 | |
| GO:905166 | 2 AT132 VPS35 | 1.6048 | |
| GO:905279 | 2 LRRK2 PRKN | 1.6048 | |
| GO:905643 | 2 MECP2 WT1 | 1.6048 | |
| GO:0006451 | 2 SELT SPCS | 1.6048 | |
| GO:0097113 | 2 SHAN3 APOE | 1.6048 | |
| GO:0097114 | 2 SHAN3 APOE | 1.6048 | |
| GO:0097501 | 2 PARK7 ATP7A | 1.6048 | |
| GO:0097688 | 2 SHAN3 APOE | 1.6048 | |
| GO:0090063 | 2 DCTN1 MECP2 | 1.6048 | |
| GO:0090276 | 12 SELT SYT9 PLPL9 TADBP CAC1D ITPR1 NDUF2 CAC1C DOC2B GTR1 ... PRKN CAC1A | 1.5998 | |
| GO:0009266 | 10 CHIP ATX3 TAU S52A3 HTRA2 CASP8 TERA TRPV4 SL9A1 SODC | 1.5995 | |
| GO:903321 | 7 OGT1 KPCG ATG5 PARK7 CAN3 TAF1 PSN1 | 1.5973 | |
| GO:903533 | 7 LRRK2 PINK1 ANK3 HUWE1 HTRA2 PRKN PRIO | 1.5973 | |
| GO:0022603 | 38 MKS1 LRRK2 OMA1 EDN1 DNM1L ADA10 TAU SYGP1 ANDR CAV3 ... CFLAR PINK1 FEZF2 APOE MECP2 DKK1 VPS35 MBP SMAD4 PRKN BDNF PROF1 GDNF DAB1 XK CF410 FOXP1 WT1 NLGN3 ADNP | 1.5942 | |
| GO:901576 | 85 COQ2 ASAH1 DPOG1 ODP2 TPK1 GTR1 ANDR IF4G1 SYRM SYDM ... APOE COQ7 PURA1 RPC2 TERA SMAD4 NPC1 NOTC3 SMN OGT1 ANGI SETD2 ELOV4 BACD1 SC5A7 TF2H2 PPM1D SYAM NHLC1 SYMM | 1.5925 | |
| GO:0033044 | 16 OGT1 LRRK2 TAU TF2H2 PHF8 SYUA XRCC1 SETD5 AUTS2 PINK1 ... PNKP ATG5 MECP2 ROA1 SMAD4 DNMT1 | 1.5845 | |
| GO:0051147 | 10 CFLAR HDAC4 BDNF EDN1 MECP2 CTDP1 DKK1 SMAD4 CAV3 DNMT1 | 1.5825 | |
| GO:0022406 | 10 MKS1 B9D2 DCTN1 TBA4A PSN2 NPHP1 TBB4A CEP41 B9D1 TTBK2 | 1.5825 | |
| GO:2000377 | 11 CFLAR HDAC4 EDN1 PRDX2 PINK1 ATG5 TAU PARK7 SYUA PRKN ... SODC | 1.5780 | |
| GO:0051402 | 5 ATN1 SIAH1 SCN2A A4 PSN1 | 1.5768 | |
| GO:0051602 | 5 PTEN PURA1 TY3H GRM1 SL9A1 | 1.5768 | |
| GO:0045921 | 7 SYT9 PLPL9 CAC1D DNM1L DOC2B AT132 SYUA | 1.5728 | |
| GO:0048814 | 7 LRRK2 DNM1L PTEN ADA10 SHAN3 DREB NLGN3 | 1.5728 | |
| GO:0046883 | 14 SYT9 TADBP ITPR1 EDN1 CAC1C GTR1 CAC1A SELT PLPL9 CAC1D ... NDUF2 DOC2B SMAD4 PRKN | 1.5727 | |
| GO:0016202 | 9 GPC1 HDAC4 ERBB4 EDN1 PTEN CTDP1 DKK1 SMAD4 CAV3 | 1.5664 | |
| GO:0010243 | 34 LRRK2 EDN1 KPCG ATX3 ASM GTR1 CAV3 SL9A1 CFLAR UBQL2 ... ATP7A TERA PRKN CAD13 DNMT1 NDUS4 SODC NPC1 OGT1 AT1A3 ACTS TRPV4 SYUA WT1 CAC1A CHIP PTEN PPP5 TY3H A4 | 1.5649 | |
| GO:0030031 | 19 MKS1 B9D2 DCTN1 ATX10 ARMC9 NEK1 B9D1 ARL3 NFH TM237 ... PIBF1 IF140 TBA4A NPHP1 TBB4A CEP41 TTBK2 CAD13 FLNA | 1.5647 | |
| GO:0051186 | 18 COQ2 ELOV4 PRDX2 COQ9 ODP2 PRDX1 TPK1 GTR1 COQ8A PARK7 ... COQ7 ELOV5 PANK2 PAHX TERA L2HDH DLP1 SODC | 1.5646 | |
| GO:0021872 | 6 BC11B ERBB4 ZSWM6 FEZF2 SHAN3 ATP7A | 1.5646 | |
| GO:903203 | 4 PINK1 PARK7 PRKN FBX7 | 1.5639 | |
| GO:0046483 | 87 DPOG1 DSRAD ATX3 TAU ODP2 S52A3 ATX1 TPK1 TYDP2 EXOS9 ... ANDR IF4G1 SYRM SYDM PURA1 RPC2 ROA1 TERA SMAD4 FRG1 SEN15 NOTC3 BC11B SMN ANGI SETD2 ELOV4 HNRH2 TF2H2 PPM1D | 1.5511 | |
| GO:901019 | 7 CACB4 PLPL9 FGF14 JPH3 HD CAV3 SL9A1 | 1.5492 | |
| GO:0043502 | 7 HDAC4 TNR1A EDN1 CTDP1 SMAD4 CAV3 SL9A1 | 1.5492 | |
| GO:0048588 | 7 AUTS2 RAPH1 BDNF CI072 A4 SPTCS NLGN3 | 1.5492 | |
| GO:0006725 | 88 DPOG1 DSRAD ATX3 TAU ODP2 ATX1 TPK1 TYDP2 EXOS9 ANDR ... IF4G1 SYRM SYDM PURA1 RPC2 ROA1 TERA SMAD4 FRG1 SEN15 NOTC3 BC11B SMN ANGI SETD2 ELOV4 HNRH2 TF2H2 PPM1D KHDR1 | 1.5489 | |
| GO:0009057 | 34 ABD12 OMA1 VLDLR ATX3 SIAH1 EXOS9 LUM SL9A1 FBX7 IF4G1 ... RNF11 UBQL2 PINK1 CASP8 TERA PRKN SQSTM NBAS UCHL1 BACD1 HTRA2 CAN3 EXOS3 ANAG EXOS8 NHLC1 PAPD1 GPC1 CHIP RS23 | 1.5469 | |
| GO:0043436 | 35 EDN1 AAKG2 ODP2 HUTU GTR1 LUM SL9A1 SYRM SYDM MECP2 ... ATP7A SC6A8 PURA1 CACP PANK2 L2HDH NPC1 ELOV4 SYAM SYUA SYMM NDUS6 TNR1A CP4V2 ACON DGLA PARK7 BCKD MYPR TY3H | 1.5461 | |
| GO:903214 | 5 LRRK2 PINK1 HUWE1 HTRA2 PRKN | 1.5434 | |
| GO:0003254 | 5 LRRK2 FHL1 ANK3 CAC1G CAV3 | 1.5434 | |
| GO:0006733 | 5 COQ2 COQ9 COQ7 COQ8A DLP1 | 1.5434 | |
| GO:0032459 | 5 DNM1L APOE GLCM SORL VPS35 | 1.5434 | |
| GO:901700 | 50 DNM1L DPOG1 TAU GTR1 ANDR CFLAR IF4G1 SGMR1 APOE NDUA9 ... TERA DKK1 OGT1 AT1A3 WT1 CAC1A ADNP XRCC1 A4 PSN1 LRRK2 EDN1 NU1M APTX RORA ASM SL9A1 SETX ATP7A GLCM | 1.5396 | |
| GO:0060420 | 6 ERBB4 EDN1 PTEN CTDP1 WT1 CAV3 | 1.5377 | |
| GO:0048663 | 6 NOTC3 BC11B FEZF2 SUFU NKX62 SMAD4 | 1.5377 | |
| GO:0034249 | 9 ANGI ABCA7 APOE GGYF2 SORL TNR6A PRIO IF4E PUM1 | 1.5337 | |
| GO:0006066 | 15 NPC2 COQ2 ASAH1 VLDLR SYNJ1 ASM ACON PTEN APOE PARK7 ... MECP2 GLCM SORL A4 NPC1 | 1.5337 | |
| GO:0090141 | 3 DNM1L VPS35 PRKN | 1.5337 | |
| GO:0099068 | 3 PTEN SHAN3 NLGN3 | 1.5337 | |
| GO:0099171 | 3 SYT9 CAC1D KPCG | 1.5337 | |
| GO:0035249 | 3 ALS2 GRID2 PRKN | 1.5337 | |
| GO:900452 | 3 SHAN3 TAU GRID2 | 1.5337 | |
| GO:905114 | 19 APCL LRRK2 PROF1 CD24 NDRG2 AMER1 WWOX GRID2 TNR6A SYUA ... CHD8 MARK1 NLGN3 DAPLE PTEN CTND2 MECP2 DKK1 VPS35 | 1.5308 | |
| GO:0001508 | 7 CAC1D KCNA1 ANK3 KCND2 CAC1G CAC1C CAV3 | 1.5301 | |
| GO:0022411 | 17 SQSTM SNX14 DCTN1 ADA10 AMER1 SYNJ1 CHM2B FBX7 VRK1 AUXI ... PINK1 TERA DKK1 PRKN CHC10 HTRA1 CHM1A | 1.5301 | |
| GO:0048511 | 14 TADBP OGT1 KPCG DNM1L RORA ANAG ADNP PTEN KCND2 HUWE1 ... SETX NDUA9 TY3H MAGL2 | 1.5287 | |
| GO:0090304 | 69 DPOG1 DSRAD ATX3 TAU ATX1 TYDP2 EXOS9 ANDR IF4G1 SYRM ... SYDM RPC2 ROA1 TERA SMAD4 FRG1 SEN15 NOTC3 BC11B SMN ANGI SETD2 HNRH2 TF2H2 PPM1D KHDR1 SYAM WT1 SYMM XRCC1 | 1.5205 | |
| GO:0090200 | 4 PLPL9 PINK1 DNM1L CHC10 | 1.5205 | |
| GO:0098901 | 4 ANK3 CAC1C CAV3 FLNA | 1.5205 | |
| GO:0042743 | 4 PRDX2 PARK7 PRDX1 SODC | 1.5205 | |
| GO:0014741 | 4 TNR1A CTDP1 SMAD4 CAV3 | 1.5205 | |
| GO:901861 | 9 GPC1 HDAC4 ERBB4 EDN1 PTEN CTDP1 DKK1 SMAD4 CAV3 | 1.5180 | |
| GO:0042493 | 35 LRRK2 EDN1 KPCG NU1M APTX ADA10 S52A3 ASM CFLAR IF4G1 ... SGMR1 PINK1 ATG5 SETX GLCM SC6A8 PURA1 CASP8 ROA1 PRKN SODC NPC1 HDAC4 DAB1 SYUA XRCC1 PTEN PARK7 PPP5 TY3H | 1.5141 | |
| GO:0080135 | 28 LRRK2 EDN1 KPCG FUS ATX3 TAU CAV3 FBX7 IF4G1 UBQL2 ... PINK1 JIP1 MET DKK1 PRKN SODC SETD2 ULK4 HTRA2 PRDX1 CHCH2 TRPV4 UBQL4 XRCC1 VP13C PTEN PARK7 A4 | 1.5141 | |
| GO:0071214 | 15 HDAC4 SCN2A CAN3 GTR1 TRPV4 SL9A1 TNR1A PTEN PURA1 CASP8 ... NEP CRADD GRM1 S12A6 TAF1 | 1.5141 | |
| GO:0104004 | 15 HDAC4 SCN2A CAN3 GTR1 TRPV4 SL9A1 TNR1A PTEN PURA1 CASP8 ... NEP CRADD GRM1 S12A6 TAF1 | 1.5141 | |
| GO:0010043 | 5 PTEN ATP7A TY3H AT132 ARGI1 | 1.5135 | |
| GO:0061097 | 7 BDNF CD24 ABI1 PTPRC A4 PRIO PSN1 | 1.5092 | |
| GO:0016049 | 7 AUTS2 RAPH1 BDNF CI072 A4 SPTCS NLGN3 | 1.5092 | |
| GO:0035295 | 32 MKS1 EDN1 MYO1E LAMA1 RORA ANDR IF4G1 MET APOE IF140 ... ATP7A HXA1 SMAD4 CAD13 S12A6 NOTC3 ANGI SETD2 PROF1 GDNF DAB1 WT1 CHD8 PTEN SEM5A SUFU NEP CXB1 ARGI1 NPRL3 | 1.5067 | |
| GO:0007623 | 9 OGT1 PTEN KCND2 HUWE1 SETX NDUA9 TY3H RORA ANAG | 1.5012 | |
| GO:0048634 | 9 GPC1 HDAC4 ERBB4 EDN1 PTEN CTDP1 DKK1 SMAD4 CAV3 | 1.5012 | |
| GO:0051188 | 11 COQ2 ELOV4 COQ9 ODP2 COQ7 TPK1 ELOV5 PANK2 COQ8A DLP1 ... SODC | 1.4949 | |
| GO:0031398 | 8 CHIP LRRK2 PINK1 PTEN HUWE1 AMER1 NHLC1 PRKN | 1.4922 | |
| GO:0033555 | 6 IF4G1 KPCG ALS2 PTEN MECP2 IF4E | 1.4855 | |
| GO:0033138 | 7 IF4G1 PINK1 PARK7 TBK1 TEN1 SYUA A4 | 1.4847 | |
| GO:0048660 | 9 NOTC3 ANGI HDAC4 EDN1 PTEN NDRG2 FOXP1 CAD13 DNMT1 | 1.4821 | |
| GO:0090199 | 5 PLPL9 PINK1 DNM1L PRKN CHC10 | 1.4785 | |
| GO:904645 | 5 AT1A3 A4 PRIO CAC1A PSN1 | 1.4785 | |
| GO:0048747 | 5 FLNC UCHL1 AFG32 XK ACTS | 1.4785 | |
| GO:0065009 | 94 CACB4 APCL VLDLR DNM1L DSRAD TAU SYGP1 ANDR DEPD5 FBX7 ... CFLAR IF4G1 PIBF1 PINK1 APOE NPRL2 PSN2 STRAB DNJB2 TERA DKK1 MBP SMAD4 CHC10 TTBK2 TIM14 UCHL1 PPR3F ANGI HDAC4 | 1.4766 | |
| GO:0009636 | 21 EDN1 PRDX2 APTX HTRA2 SELT IF4G1 SGMR1 PINK1 PTEN APOE ... SETX PARK7 ATP7A PPP5 CASP8 TY3H ROA1 ARGI1 MBP PRKN SODC | 1.4766 | |
| GO:0001662 | 4 IF4G1 ALS2 MECP2 IF4E | 1.4757 | |
| GO:0021696 | 4 SPTN2 ATP7A RORA GRID2 | 1.4757 | |
| GO:0016197 | 11 SQSTM VPS53 DCTN1 ALS2 DNM1L CHM2B TERA VPS35 CCD22 MAGL2 ... TBC23 | 1.4654 | |
| GO:902850 | 7 SETD2 DCTN1 PIBF1 HD TBCE MECP2 FLNA | 1.4640 | |
| GO:0000303 | 3 PRDX2 ATP7A SODC | 1.4640 | |
| GO:0060134 | 3 PTEN GRID2 CHD8 | 1.4640 | |
| GO:0071218 | 3 CHIP ATX3 TERA | 1.4640 | |
| GO:0097106 | 3 PTEN SHAN3 SYGP1 | 1.4640 | |
| GO:900451 | 3 PINK1 SHAN3 NLGN3 | 1.4640 | |
| GO:2001242 | 10 LRRK2 PINK1 JIP1 DNM1L NDUS3 SIAH1 PARK7 HTRA2 PRKN SODC | 1.4605 | |
| GO:0050789 | 285 MKS1 DCTN1 ADA10 DSRAD GRB14 SCN2A TYDP2 EXOS9 RERE DEPD5 ... FBX7 CFLAR IF4G1 AGRG2 DAPLE RB39B SCN3A T106B CASPA RPC2 PSN2 DKK1 VPS35 TFG SMAD4 TTBK2 UCHL1 PPR3F ANGI SETD2 | 1.4576 | |
| GO:0007018 | 12 KIF5A UCHL1 KIF1C HD TAU IF140 BICD2 TRAK2 A4 ARL3 ... SPTCS SODC | 1.4561 | |
| GO:0008203 | 8 NPC2 VLDLR APOE GLCM SORL ASM A4 NPC1 | 1.4556 | |
| GO:0051282 | 8 ITPR1 JPH3 HD ATG5 PTPRC CAC1C CAN3 SYUA | 1.4556 | |
| GO:0051817 | 8 TADBP ATG5 APOE CTDP1 CASP8 VAPB PRKN CHD1 | 1.4556 | |
| GO:0006897 | 18 LRRK2 VLDLR MYO1E DNM1L REPS1 TF2H2 RBG1L SYNJ1 SYUA CAV3 ... NLGN3 AUXI CI072 APOE SORL A4 RUBIC NPC1 | 1.4484 | |
| GO:0010608 | 21 TADBP ANGI CLP1 GDNF DSRAD KHDR1 EXOS9 TNR6A EXOS3 EXOS8 ... SELT IF4G1 ATX2 PINK1 GGYF2 MATR3 A4 RL10 SPCS IF4E PUM1 | 1.4484 | |
| GO:0022402 | 33 DCTN1 AAKG2 REEP3 TBCE PHF8 CHM2B OPTN ARL3 POGZ ANX11 ... VRK1 PIBF1 MECP2 GGYF2 STRAB CE120 SETD2 ANK3 PPM1D KHDR1 CAN3 HD TBA4A CTDP1 PTPRC TBB4A CEP41 CRADD PRIO IF4E | 1.4484 | |
| GO:0031058 | 7 OGT1 LRRK2 AUTS2 PINK1 MECP2 SMAD4 DNMT1 | 1.4484 | |
| GO:0048589 | 17 SPTN2 RAPH1 ERBB4 BDNF DIA1 ANDR NLGN3 CFLAR NDUS6 AUTS2 ... CI072 PTEN NLGNX GGYF2 A4 SMAD4 SPTCS | 1.4484 | |
| GO:0006082 | 35 EDN1 AAKG2 ODP2 HUTU GTR1 LUM SL9A1 SYRM SYDM MECP2 ... ATP7A SC6A8 PURA1 CACP PANK2 L2HDH NPC1 ELOV4 SYAM SYUA SYMM NDUS6 TNR1A CP4V2 ACON DGLA PARK7 BCKD MYPR TY3H | 1.4484 | |
| GO:0090206 | 2 APOE SODC | 1.4484 | |
| GO:900825 | 2 ANK3 CAV3 | 1.4484 | |
| GO:0000423 | 2 SQSTM PRKN | 1.4484 | |
| GO:902498 | 2 LRRK2 TAF1 | 1.4484 | |
| GO:0042985 | 2 ABCA7 ITM2B | 1.4484 | |
| GO:0034982 | 2 OMA1 MPPA | 1.4484 | |
| GO:0150003 | 2 A4 PRKN | 1.4484 | |
| GO:903208 | 2 PINK1 PARK7 | 1.4484 | |
| GO:903207 | 2 PINK1 PARK7 | 1.4484 | |
| GO:0010961 | 2 TRPM7 XK | 1.4484 | |
| GO:903335 | 2 LRRK2 VPS35 | 1.4484 | |
| GO:0060161 | 2 LRRK2 VPS35 | 1.4484 | |
| GO:0086045 | 2 CAC1G CAC1C | 1.4484 | |
| GO:0086046 | 2 CAC1D CAC1G | 1.4484 | |
| GO:904959 | 2 ATP7A CHC10 | 1.4484 | |
| GO:0061734 | 2 OPTN PRKN | 1.4484 | |
| GO:0045541 | 2 APOE SODC | 1.4484 | |
| GO:0070127 | 2 SYDM SYAM | 1.4484 | |
| GO:905448 | 2 PINK1 PARK7 | 1.4484 | |
| GO:0021942 | 2 DAB1 RERE | 1.4484 | |
| GO:0097107 | 2 PTEN SHAN3 | 1.4484 | |
| GO:990049 | 2 KIF5A KIF1C | 1.4484 | |
| GO:0106119 | 2 APOE SODC | 1.4484 | |
| GO:0016191 | 2 AUXI SYNJ1 | 1.4484 | |
| GO:0042180 | 6 COQ2 COQ9 PARK7 COQ7 COQ8A DLP1 | 1.4467 | |
| GO:0007422 | 6 GPC1 SCN8A GDNF NEUS NFH SODC | 1.4467 | |
| GO:0002209 | 4 IF4G1 ALS2 MECP2 IF4E | 1.4457 | |
| GO:0035850 | 4 MYO1E GDNF CD24 WT1 | 1.4457 | |
| GO:0036465 | 4 AUXI DNM1L SYNJ1 SYUA | 1.4457 | |
| GO:0014002 | 4 TAU MYPR A4 PSN1 | 1.4457 | |
| GO:0097061 | 4 PTEN CTND2 SHAN3 PRIO | 1.4457 | |
| GO:0006399 | 10 SYRM SEN34 CLP1 SYDM SEN2 SEN54 SYAM SPCS SEN15 SYMM | 1.4430 | |
| GO:0010817 | 22 SYT9 TADBP ITPR1 EDN1 SC5A7 CAC1C GTR1 TRPV4 CLCN2 CAC1A ... SELT PLPL9 CHIP CAC1D NDUF2 PARK7 MECP2 DOC2B PCLO NEP SMAD4 PRKN | 1.4370 | |
| GO:0061337 | 7 CACB4 CAC1D AT1A3 KCND2 CAC1G CAC1C SL9A1 | 1.4325 | |
| GO:0009267 | 9 LRRK2 NPRL2 PPM1D GLCM ROA1 TNR6A GTR1 NPRL3 DEPD5 | 1.4275 | |
| GO:0098930 | 5 KIF5A UCHL1 KIF1C TAU SODC | 1.4275 | |
| GO:0045843 | 5 PTEN CTDP1 DKK1 SMAD4 CAV3 | 1.4275 | |
| GO:0035966 | 10 CHIP DCTN1 HSPB3 ATX3 TPP1 VAPB DNJB2 TERA OPTN PRKN | 1.4271 | |
| GO:901983 | 6 SETD5 AUTS2 ATG5 PARK7 SYUA SMAD4 | 1.4214 | |
| GO:0019216 | 18 BC11B NPC2 BSCL2 ASAH1 AAKG2 RORA SYUA CLCN2 PLPL9 CHIP ... TNR1A PIBF1 APOE ELOV5 PANK2 PI3R5 RUBIC SODC | 1.4192 | |
| GO:0040007 | 17 SPTN2 RAPH1 ERBB4 BDNF DIA1 ANDR NLGN3 CFLAR NDUS6 AUTS2 ... CI072 PTEN NLGNX GGYF2 A4 SMAD4 SPTCS | 1.4144 | |
| GO:0006139 | 81 DPOG1 DSRAD ATX3 TAU ODP2 ATX1 TYDP2 EXOS9 ANDR IF4G1 ... SYRM SYDM PURA1 RPC2 ROA1 TERA SMAD4 FRG1 SEN15 NOTC3 BC11B SMN ANGI SETD2 ELOV4 HNRH2 TF2H2 PPM1D KHDR1 SYAM | 1.4144 | |
| GO:0043170 | 162 ABD12 ABCA7 VLDLR ADA10 DSRAD TAU TYDP2 EXOS9 FBX7 CFLAR ... IF4G1 PINK1 CASPA RPC2 PSN2 SCYL1 ROA1 MBP SMAD4 TTBK2 FRG1 SEN15 NPC1 BC11B SMN UCHL1 ANGI SETD2 HDAC4 ERBB4 | 1.4134 | |
| GO:0055085 | 41 CACB4 ABCA7 ITPR1 AAKG2 KCNA1 AFG32 CAC1G S6A19 SCN2A CAC1C ... TM175 GTR1 CLCN2 SL9A1 CAC1D SL9A9 ATP7A SC6A8 TERA S17A5 MPPB JPH3 SC5A7 AT1A3 SURF1 MPPA AT132 GRID2 S35A3 TRPV4 | 1.4134 | |
| GO:0001763 | 10 MKS1 SETD2 EDN1 MET LAMA1 GDNF WT1 SMAD4 ANDR RERE | 1.4130 | |
| GO:0046620 | 7 ERBB4 EDN1 PTEN CTDP1 WT1 CAV3 SODC | 1.4130 | |
| GO:0071705 | 51 VLDLR S52A3 FBX7 APOE IF140 CACP STRAB ROA1 TERA VPS35 ... TIM14 ANK3 CD24 AT132 S35A3 CEP41 PAHX RL10 PSN1 KIF5A LRRK2 SNX14 EDN1 S6A19 CCD22 OPTN DJC13 ARL3 VPS53 ATX2 | 1.4130 | |
| GO:0000305 | 3 PRDX2 ATP7A SODC | 1.4130 | |
| GO:0099084 | 3 PTEN SHAN3 SYGP1 | 1.4130 | |
| GO:0051571 | 3 AUTS2 SMAD4 DNMT1 | 1.4130 | |
| GO:0019228 | 3 KCNA1 ANK3 KCND2 | 1.4130 | |
| GO:0061318 | 3 MYO1E CD24 WT1 | 1.4130 | |
| GO:0072112 | 3 MYO1E CD24 WT1 | 1.4130 | |
| GO:0032225 | 3 PINK1 GDNF SYUA | 1.4130 | |
| GO:0008090 | 3 KIF5A KIF1C SODC | 1.4130 | |
| GO:0006468 | 34 LRRK2 SPTN2 KPCG AAKG2 LAMA1 ADA10 SYGP1 TBK1 MARK1 VRK1 ... PIBF1 PINK1 JIP1 MET SETX NPRL2 SCYL1 MBP TTBK2 SQSTM ERBB4 ULK4 GDNF TF2H2 PPM1D ABI1 NEK1 AT132 SHAN3 TRPM7 | 1.4124 | |
| GO:0030163 | 23 SQSTM UCHL1 ABD12 OMA1 VLDLR BACD1 ATX3 SIAH1 HTRA2 CAN3 ... NHLC1 FBX7 GPC1 CHIP RNF11 UBQL2 PINK1 TPP1 CASP8 FBX38 TERA PRKN TAF1 | 1.4094 | |
| GO:0042596 | 4 IF4G1 ALS2 MECP2 IF4E | 1.4062 | |
| GO:0051241 | 41 LRRK2 EDN1 NDRG2 SYGP1 TBK1 NKX62 CAV3 FBX7 PIBF1 FEZF2 ... APOE MECP2 NLGNX GLCM SORL DKK1 SMAD4 DNMT1 SODC NOTC3 HDAC4 ERBB4 PRDX2 CD24 DAB1 TRPV4 WT1 NLGN3 TNR1A FIG4 | 1.4011 | |
| GO:903793 | 5 PLPL9 ABCA7 EDN1 APOE PSN1 | 1.4006 | |
| GO:905207 | 5 EDN1 CTDP1 DKK1 SMAD4 CAV3 | 1.4006 | |
| GO:0048635 | 5 PTEN CTDP1 DKK1 SMAD4 CAV3 | 1.4006 | |
| GO:0006732 | 12 COQ2 ELOV4 COQ9 ODP2 COQ7 TPK1 ELOV5 PANK2 GTR1 TERA ... COQ8A DLP1 | 1.3947 | |
| GO:0017158 | 7 SYT9 LRRK2 CAC1D KPCG DNM1L DOC2B VAMP1 | 1.3944 | |
| GO:2001243 | 7 LRRK2 PINK1 JIP1 NDUS3 PARK7 HTRA2 PRKN | 1.3944 | |
| GO:0032102 | 16 EDN1 PRDX2 DSRAD RORA GRID2 CHD8 TNR1A PTEN APOE GLCM ... PTPRC SEM5A VPS35 ARGI1 HTRA1 SODC | 1.3874 | |
| GO:901565 | 33 ABD12 OMA1 ASAH1 VLDLR ATX3 SIAH1 HUTU ASM LUM SL9A1 ... FBX7 RNF11 UBQL2 PINK1 GLCM CASP8 TERA PRKN SQSTM UCHL1 BACD1 HTRA2 CAN3 ANAG NHLC1 PDE8B GPC1 CHIP TPP1 BCKD | 1.3869 | |
| GO:0009890 | 48 ATN1 ABCA7 EDN1 VLDLR ITM2B ATX1 TYDP2 NKX62 ANDR RERE ... CFLAR PIBF1 FEZF2 APOE MECP2 GGYF2 ROA1 DKK1 SMAD4 PRKN DNMT1 SODC PUM1 NOTC3 SQSTM ANGI HDAC4 NIF3L PPM1D WWOX | 1.3865 | |
| GO:0040029 | 11 HDAC4 TBP CLP1 DSRAD MECP2 PHF8 PPM1D GGYF2 TNR6A DNMT1 ... PUM1 | 1.3863 | |
| GO:901564 | 142 ABD12 ABCA7 ASAH1 VLDLR ADA10 TAU ODP2 S52A3 TPK1 FBX7 ... CFLAR IF4G1 PINK1 CASPA PSN2 SCYL1 CACP MBP SMAD4 TTBK2 NPC1 UCHL1 SETD2 HDAC4 ERBB4 ELOV4 TF2H2 UBA5 ABI1 NEK1 | 1.3861 | |
| GO:0006974 | 28 FAN1 APTX DPOG1 ATX3 TYDP2 TYDP1 PNKP HUWE1 SETX GGYF2 ... BRAT1 TERA SETD2 TF2H2 HTRA2 PPM1D CF410 FOXP1 NEK1 UBQL4 XRCC1 CHIP TNR1A PARK7 PPP5 CRADD TAF1 PSN1 | 1.3732 | |
| GO:0043410 | 21 LRRK2 ABCA7 ERBB4 EDN1 PRDX2 CD24 TRPV4 ANDR CFLAR JIP1 ... PTEN FCRL3 APOE PTPRC TEN1 DKK1 A4 GRM1 PI3R5 PSN1 SODC | 1.3680 | |
| GO:0061900 | 4 TAU SYUA A4 PSN1 | 1.3636 | |
| GO:0006801 | 4 EDN1 PRDX2 ATP7A SODC | 1.3636 | |
| GO:0008219 | 38 LRRK2 ATN1 ITPR1 DNM1L SIAH1 SCN2A OPTN SL9A1 CFLAR SGMR1 ... ALS2 ATG5 BRAT1 CASPA CASP8 VPS35 SQSTM OGT1 ERBB4 NDUS1 CD24 HTRA2 WWOX UNC5C CAN3 SYUA CAC1A TNR1A HD PTEN | 1.3555 | |
| GO:2000300 | 6 SYT9 LRRK2 CAC1D KPCG DNM1L VAMP1 | 1.3511 | |
| GO:0051952 | 6 PINK1 GDNF SYUA ARGI1 PRKN PSN1 | 1.3511 | |
| GO:0006892 | 6 VP13C ANK3 SORL CCD22 OPTN ARL3 | 1.3511 | |
| GO:0007224 | 6 MKS1 PTHD1 SUFU B9D1 ARL3 TTBK2 | 1.3511 | |
| GO:0120031 | 18 MKS1 B9D2 DCTN1 ATX10 ARMC9 NEK1 B9D1 ARL3 TM237 PIBF1 ... IF140 TBA4A NPHP1 TBB4A CEP41 TTBK2 CAD13 FLNA | 1.3511 | |
| GO:901017 | 3 ANK3 PTEN CAV3 | 1.3511 | |
| GO:2001267 | 3 PARK7 HTRA2 CASP8 | 1.3511 | |
| GO:0051788 | 3 CHIP ATX3 TERA | 1.3511 | |
| GO:0010832 | 3 CFLAR HDAC4 BDNF | 1.3511 | |
| GO:0060997 | 3 PTEN CTND2 SHAN3 | 1.3511 | |
| GO:0086012 | 3 CAC1D CAC1G CAC1C | 1.3511 | |
| GO:0055069 | 3 ATP7B AT132 PRKN | 1.3511 | |
| GO:0072311 | 3 MYO1E CD24 WT1 | 1.3511 | |
| GO:0034613 | 43 KIF5A LRRK2 ABCA7 KCNA1 DNM1L SYGP1 OPTN ARL3 CAV3 FBX7 ... PIBF1 PINK1 APOE IF140 CACP STRAB SORL TERA VPS35 EFR3A PRKN CHC10 TIM14 NPC1 SYNE1 ANK3 CD24 MPPA BICD2 CAN3 | 1.3508 | |
| GO:0016070 | 52 DSRAD TAU ATX1 EXOS9 ANDR IF4G1 SYRM SYDM RPC2 ROA1 ... SMAD4 FRG1 SEN15 NOTC3 SMN ANGI SETD2 HNRH2 TF2H2 PPM1D KHDR1 SYAM WT1 SYMM CTDP1 SEN54 A4 RL10 FLNA SEN34 | 1.3442 | |
| GO:0033135 | 8 IF4G1 PINK1 PARK7 TBK1 TEN1 DKK1 SYUA A4 | 1.3418 | |
| GO:0090174 | 5 CHM2B TM175 SYUA SPTCS VAMP1 | 1.3412 | |
| GO:901862 | 5 PTEN CTDP1 DKK1 SMAD4 CAV3 | 1.3412 | |
| GO:0035065 | 5 SETD5 AUTS2 ATG5 SYUA SMAD4 | 1.3412 | |
| GO:0070727 | 43 KIF5A LRRK2 ABCA7 KCNA1 DNM1L SYGP1 OPTN ARL3 CAV3 FBX7 ... PIBF1 PINK1 APOE IF140 CACP STRAB SORL TERA VPS35 EFR3A PRKN CHC10 TIM14 NPC1 SYNE1 ANK3 CD24 MPPA BICD2 CAN3 | 1.3354 | |
| GO:0010522 | 7 JPH3 HD ATG5 CAC1C CAN3 SYUA PRIO | 1.3332 | |
| GO:0097327 | 7 CFLAR EDN1 ADA10 GLCM ROA1 ARGI1 IF4E | 1.3332 | |
| GO:0051051 | 20 LRRK2 ABCA7 EDN1 ANK3 FRM4A SYUA CAV3 ATX2 TNR1A UBQL2 ... NDUF2 PTEN ATG5 APOE PARK7 ATP7A SUFU VPS35 PRKN RUBIC | 1.3322 | |
| GO:0030111 | 16 MKS1 APCL LRRK2 AMER1 WWOX CHD8 TM237 CTND2 APOE SEM5A ... TERA DKK1 VPS35 A4 PRKN PSN1 | 1.3300 | |
| GO:0031397 | 6 OGT1 KPCG ATG5 PARK7 TAF1 PSN1 | 1.3292 | |
| GO:2001252 | 10 OGT1 LRRK2 AUTS2 PINK1 PNKP TF2H2 MECP2 ROA1 SMAD4 DNMT1 | 1.3292 | |
| GO:901031 | 4 LRRK2 PINK1 MET PARK7 | 1.3288 | |
| GO:2000785 | 4 LRRK2 UBQL2 PINK1 CI072 | 1.3288 | |
| GO:0070509 | 4 CAC1D AFG32 CAC1G TRPV4 | 1.3288 | |
| GO:0033036 | 66 ABCA7 VLDLR DNM1L ATX3 SYGP1 FBX7 PIBF1 SGMR1 PINK1 APOE ... IF140 CACP STRAB ROA1 TERA VPS35 CHC10 TIM14 NPC1 NPC2 SYNE1 ANK3 CD24 CAN3 CNTP2 SHAN3 DOC2B CEP41 DREB PAHX | 1.3287 | |
| GO:0036294 | 11 CFLAR CHIP EDN1 PINK1 DNM1L PTEN KCND2 ATP7A SCN2A RORA ... SL9A1 | 1.3287 | |
| GO:0044271 | 52 ASAH1 DPOG1 ODP2 TPK1 ANDR IF4G1 SYRM SYDM PURA1 RPC2 ... TERA SMAD4 NOTC3 SMN ANGI SETD2 ELOV4 TF2H2 PPM1D SYAM SYMM AMPD2 CTDP1 RL10 TMLH FLNA AAKG2 RORA ASM FMT | 1.3287 | |
| GO:0045861 | 15 OGT1 LRRK2 KPCG SYUA CFLAR PARK7 FHIT BIRC1 SUFU SORL ... A4 PRIO TAF1 PSN1 T4S20 | 1.3287 | |
| GO:0032101 | 37 LRRK2 ABD12 EDN1 KPCG ADA10 DSRAD TBK1 RORA OPTN TBC23 ... FEZF2 MET APOE GLCM RPC2 CASP8 VPS35 CAD13 SODC PUM1 PRDX2 FOXP1 CAN3 GRID2 TRPV4 SYUA CHD8 TNR1A PTEN FCRL3 | 1.3287 | |
| GO:0098902 | 2 ANK3 CAV3 | 1.3287 | |
| GO:0033603 | 2 PINK1 GDNF | 1.3287 | |
| GO:901727 | 2 LRRK2 PINK1 | 1.3287 | |
| GO:0099519 | 2 KIF5A KIF1C | 1.3287 | |
| GO:901950 | 2 KIF5A KIF1C | 1.3287 | |
| GO:902177 | 2 PARK7 SODC | 1.3287 | |
| GO:0034447 | 2 VLDLR APOE | 1.3287 | |
| GO:2000618 | 2 AUTS2 ATG5 | 1.3287 | |
| GO:0051123 | 2 TBP TAF1 | 1.3287 | |
| GO:0051582 | 2 PRKN PSN1 | 1.3287 | |
| GO:0035434 | 2 ATP7B ATP7A | 1.3287 | |
| GO:0010968 | 2 DCTN1 MECP2 | 1.3287 | |
| GO:0035900 | 2 ACON TY3H | 1.3287 | |
| GO:0035973 | 2 SQSTM ATG5 | 1.3287 | |
| GO:904415 | 2 TBK1 OPTN | 1.3287 | |
| GO:904417 | 2 TBK1 OPTN | 1.3287 | |
| GO:904683 | 2 SORL MBP | 1.3287 | |
| GO:904732 | 2 ATP7A CHC10 | 1.3287 | |
| GO:0045915 | 2 PARK7 VPS35 | 1.3287 | |
| GO:0045964 | 2 PARK7 VPS35 | 1.3287 | |
| GO:0070842 | 2 TERA PRKN | 1.3287 | |
| GO:0021924 | 2 RORA RERE | 1.3287 | |
| GO:0021930 | 2 RORA RERE | 1.3287 | |
| GO:0072318 | 2 AUXI SYNJ1 | 1.3287 | |
| GO:0032253 | 2 KIF5A KIF1C | 1.3287 | |
| GO:0015871 | 2 SC6A8 PSN1 | 1.3287 | |
| GO:0032510 | 2 CHM2B TERA | 1.3287 | |
| GO:0120034 | 7 AUTS2 HDAC4 HD PROF1 ATP7A TEN1 CE120 | 1.3258 | |
| GO:0016441 | 5 CLP1 DSRAD GGYF2 TNR6A PUM1 | 1.3250 | |
| GO:0071385 | 5 CFLAR EDN1 NU3M ARGI1 IF4E | 1.3250 | |
| GO:903522 | 14 CACB4 HDAC4 ITPR1 EDN1 AT1A3 CAC1G CAC1C CAV3 SL9A1 CAC1D ... KCND2 TY3H AT2B3 FLNA | 1.3235 | |
| GO:0006720 | 8 GPC1 CP4V2 COQ2 APOE HTRA2 TY3H PAHX DLP1 | 1.3203 | |
| GO:0051171 | 153 ABCA7 VLDLR DNM1L DSRAD TAU TYDP2 EXOS9 RERE FBX7 CFLAR ... IF4G1 DAPLE PINK1 CARTF STRAB ROA1 DNJB2 DKK1 VPS35 MBP SMAD4 BC11B UCHL1 ANGI SETD2 HDAC4 ERBB4 BDNF CD24 ABI1 | 1.3186 | |
| GO:0042632 | 6 NPC2 APOE CD24 RORA CAV3 NPC1 | 1.3186 | |
| GO:0051094 | 45 EDN1 VLDLR DNM1L TAU NKX62 ANDR CAV3 SOX5 CFLAR IF4G1 ... FEZF2 T106B APOE SETX CASP8 DKK1 VPS35 SMAD4 PRKN ERBB4 BDNF GDNF CD24 DAB1 CAN3 GRID2 EXOS3 WT1 NLGN3 ADNP | 1.3121 | |
| GO:901701 | 34 LRRK2 EDN1 DNM1L DPOG1 TAU RORA ANDR SL9A1 CFLAR SGMR1 ... SETX ATP7A TERA PRKN DNMT1 SODC PRDX2 AT1A3 HTRA2 SYUA WT1 CAC1A SELT LITAF PTEN PARK7 PPP5 TY3H A4 ARGI1 | 1.3080 | |
| GO:0099054 | 3 PTEN NLGNX NLGN3 | 1.3080 | |
| GO:0034643 | 3 UCHL1 TAU TRAK2 | 1.3080 | |
| GO:0035994 | 3 EDN1 CAV3 SL9A1 | 1.3080 | |
| GO:0061050 | 3 EDN1 CTDP1 CAV3 | 1.3080 | |
| GO:0061912 | 3 SQSTM ATG5 PRKN | 1.3080 | |
| GO:0021533 | 3 ATP7A RORA GRID2 | 1.3080 | |
| GO:0047497 | 3 UCHL1 TAU TRAK2 | 1.3080 | |
| GO:0072074 | 3 AMER1 WT1 SMAD4 | 1.3080 | |
| GO:0031293 | 3 ADA10 PSN2 PSN1 | 1.3080 | |
| GO:0032460 | 3 GLCM SORL VPS35 | 1.3080 | |
| GO:0010259 | 4 NDUS6 LRRK2 EDN1 TY3H | 1.3057 | |
| GO:0150076 | 4 TAU SYUA A4 PSN1 | 1.3057 | |
| GO:0097009 | 4 IF4G1 OMA1 AMPD2 TRPV4 | 1.3057 | |
| GO:0072595 | 4 PINK1 SYNE1 PARK7 GPAA1 | 1.3057 | |
| GO:0060249 | 15 MKS1 FGGY DCTN1 PRDX1 CHM2B CAN3 CAV3 XRCC1 CAC1D GGYF2 ... TPP1 AT2B3 DNJB2 PRKN SODC | 1.3049 |