RiceNetDB is currently the most comprehensive regulatory database on Oryza Sativa based on genome annotation. It was displayed in three levels: GEM, PPIs and GRNs to facilitate biomolecular regulatory analysis and gene-metabolite mapping.
| General Information | |
|---|---|
| Protein ID | LOC_Os02g56050 View Network |
| Names | Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) [Includes: Molybdopterin-synthase adenylyltransferase (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase); Molybdopterin-synthase sulfurtransferase (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)] |
| Function | Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions (By similarity). |
| Attributes | Length: 176 Status: Complete Existence: Inferred from homology Molecular Weight: 19871.6 pI: 7.8934 Subcellular Location (predicted): Cytosol Chloroplast |
| Gene Model | LOC_Os02g56050.1 |
| Enzyme | 2.7.7.- Nucleotidyltransferases |
| Reactions | |
|---|---|
| OSR2803 | |
| Database Links | |
|---|---|
| UniprotKB | A3ACF3 |
| EMBL | CM000139 |
| KEGG | osa:9268394 dosa:Os02t0804600-00 |