General Information
Protein IDLOC_Os07g31460        View Network
NamesPeptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (Peptide:N-glycanase)
FunctionSpecifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins (By similarity).
AttributesLength: 785
Status: Complete
Existence: Evidence at transcript level
Molecular Weight: 87889
pI: 4.7568
Subcellular Location (adjusted): Cytosol    
Gene ModelLOC_Os07g31460.1  LOC_Os07g31460.2  
Enzyme3.5.1.52  peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase
Protein-Protein Interaction ( Show in Viewer )
LOC_Os02g54340   LOC_Os06g15360   LOC_Os02g08300   
Database Links
UniprotKBQ7F0R1
RefseqNP_001059707.1  
EMBLAP004259  AP004006  
KEGGosa:4343301  dosa:Os07t0497400-01