General Information
Protein IDLOC_Os08g14770        View Network
NamesBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial (Bifunctional BIO3-BIO1 protein) [Includes: Dethiobiotin synthetase (DTB synthetase) (DTBS) (Protein BIOTIN AUXOTROPH 3); 7,8-diamino-pelargonic acid aminotransferase (DAPA AT) (DAPA aminotransferase) (7,8-diaminononanoate synthase) (DANS) (Adenosylmethionine-8-amino-7-oxononanoate aminotransferase) (Diaminopelargonic acid synthase) (Protein BIOTIN AUXOTROPH 1)]
FunctionBifunctional enzyme that catalyzes two different reactions involved in the biotin biosynthesis.; Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity).; Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity).
AttributesLength: 822
Status: Complete
Existence: Evidence at transcript level
Molecular Weight: 90048.4
pI: 6.7543
Subcellular Location (predicted): Mitochondria  Chloroplast  
Gene ModelLOC_Os08g14770.1  
Enzyme2.6.1.62  adenosylmethionine---8-amino-7-oxononanoate transaminase
Reactions
OSR1396  
Protein-Protein Interaction ( Show in Viewer )
LOC_Os10g32550  LOC_Os02g03540   LOC_Os03g50540   
Pathways
KEGG Pathwayrn00780  rn01100  
Metacyc PathwayPWY-3701  BIOTIN-SYNTHESIS-PWY  
Database Links
UniprotKBQ6ZKV8
EnsemblLOC_Os08g14770.1  
RefseqNP_001061354.1  
EMBLAP003859  AP008214  CM000145  AK100945  
KEGGosa:4345056  dosa:Os08t0245400-01