General Information
Protein IDLOC_Os09g25320        View Network
NamesUbiquitin-NEDD8-like protein RUB1 [Cleaved into: Ubiquitin; NEDD8-like protein RUB1 (OsRUB1) (Ubiquitin-related protein 1)]
FunctionUbiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, and DNA-damage responses. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).; NEDD8-like protein RUB1: Appears to function as a stable post-translational protein modifier.
AttributesLength: 154
Status: Complete
Existence: Evidence at transcript level
Molecular Weight: 17129.7
pI: 5.8485
Subcellular Location (adjusted): Cytosol    
Gene ModelLOC_Os09g25320.1  
Protein-Protein Interaction ( Show in Viewer )
LOC_Os10g02500  LOC_Os01g27150   
Database Links
UniprotKBP0C030
RefseqNP_001063199.1  
EMBLAP005426  AP005579  
KEGGosa:4347085  dosa:Os09t0420800-01