RiceNetDB is currently the most comprehensive regulatory database on Oryza Sativa based on genome annotation. It was displayed in three levels: GEM, PPIs and GRNs to facilitate biomolecular regulatory analysis and gene-metabolite mapping.
| General Information | |
|---|---|
| Protein ID | LOC_Os12g26060 View Network |
| Names | Putative bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS) [Includes: Dihydrofolate reductase ; Thymidylate synthase ] |
| Function | Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity). |
| Attributes | Length: 470 Status: Complete Existence: Inferred from homology Molecular Weight: 53201.4 pI: 7.9734 Subcellular Location (adjusted): Cytosol |
| Gene Model | LOC_Os12g26060.1 |
| Protein-Protein Interaction ( Show in Viewer ) |
|---|
| LOC_Os04g16771 |
| Database Links | |
|---|---|
| UniprotKB | Q2QRX6 |
| EMBL | DP000011 |
| KEGG | osa:9271078 dosa:Os12t0446900-01 |