| 26S |
proteasome 26S |
protein |
P60900 |
| Abeta |
amyloid beta protein 40/42 |
protein |
CHEMBL2487 |
| ACh |
O-Acetylcholine |
small molecule |
CHEMBL667 |
| ACTB |
actin beta |
protein |
P60709 |
| ACTG1 |
actin gamma 1 |
protein |
P63261 |
| AGER |
advanced glycosylation end-product specific receptor |
protein |
Q15109 |
| AKT1 |
AKT serine/threonine kinase 1 |
protein |
P31749 |
| AKT2 |
AKT serine/threonine kinase 2 |
protein |
P31751 |
| AKT3 |
AKT serine/threonine kinase 3 |
protein |
Q9Y243 |
| ALY |
Aly/REF export factor |
protein |
Q86V81 |
| AMBRA1 |
autophagy and beclin 1 regulator 1 |
protein |
Q9C0C7 |
| APAF1 |
apoptotic peptidase activating factor 1 |
protein |
O14727 |
| APP |
amyloid beta precursor protein |
protein |
P05067 |
| ARP |
actin related protein |
protein |
P61163 |
| ATF2 |
activating transcription factor 2 |
protein |
P15336 |
| ATF4 |
activating transcription factor 4 |
protein |
P18848 |
| ATF6 |
cyclic AMP-dependent transcription factor ATF-6 alpha |
protein |
P18850 |
| ATF6B |
activating transcription factor 6 beta |
protein |
Q99941 |
| ATG101 |
autophagy related 101 |
protein |
Q9BSB4 |
| ATG13 |
autophagy related 13 |
protein |
O75143 |
| ATG14 |
autophagy related 14 |
protein |
Q6ZNE5 |
| ATXN2 |
ataxin 2 |
protein |
Q99700 |
| ATXN3 |
ataxin 3 |
protein |
P54252 |
| BAD |
BCL2 associated agonist of cell death |
protein |
Q92934 |
| BAK1 |
BCL2 antagonist/killer 1 |
protein |
Q16611 |
| BAX |
BCL2 associated X, apoptosis regulator |
protein |
Q07812 |
| BBC3 |
BCL2 binding component 3 |
protein |
Q96PG8 |
| BCL2 |
apoptosis regulator Bcl-2 |
protein |
P10415 |
| BCL2L1 |
Bcl-2-like 1(apoptosis regulator Bcl-X) |
protein |
Q07817 |
| BCL2L11 |
Bcl-2-like protein 11 |
protein |
O43521 |
| BECN1 |
beclin 1 |
protein |
Q14457 |
| BH4 |
Tetrahydrobiopterin |
small molecule |
CHEMBL1201774 |
| BID |
BH3 interacting domain death agonist |
protein |
P55957 |
| BIP |
endoplasmic reticulum chaperone BiP |
protein |
P11021 |
| C9orf72 |
guanine nubleotide exchange protein C9orf72 |
protein |
Q96LT7 |
| Ca |
Calcium |
small molecule |
CHEMBL5072826 |
| CACNA1A |
calcium voltage-gated channel subunit alpha1 A |
protein |
O00555 |
| CACNA1B |
calcium voltage-gated channel subunit alpha1 B |
protein |
Q00975 |
| CAPN |
calpain |
protein |
P07384 |
| CASP10 |
caspase 10 |
protein |
Q92851 |
| CASP3 |
caspase 3 |
protein |
P42574 |
| CASP7 |
caspase 7 |
protein |
P55210 |
| CASP8 |
caspase 8 |
protein |
Q14790 |
| CASP9 |
caspase 9 |
protein |
P55211 |
| CAV1 |
caveolin 1 |
protein |
Q03135 |
| CAV2 |
caveolin 2 |
protein |
P51636 |
| CAV3 |
caveolin 3 |
protein |
P56539 |
| CDCREL1 |
septin 5 |
protein |
Q99719 |
| CDK5 |
cyclin-dependent kinase 5 |
protein |
Q00535 |
| CDK5R1 |
cyclin-dependent kinase 5 activator 1 |
protein |
Q15078 |
| CHRNA7 |
nicotinic acetylcholine receptor alpha 7 |
protein |
P36544 |
| CISD1 |
CDGSH iron sulfur domain 1 |
protein |
Q9NZ45 |
| CISD2 |
CDGSH iron sulfur domain 2 |
protein |
Q8N5K1 |
| CK2 |
casein kinase 2 |
protein |
P68400 |
| CREB1 |
cAMP responsive element binding protein 1 |
protein |
P16220 |
| CREB3 |
cAMP responsive element binding protein 3 |
protein |
O43889 |
| CREB3L1 |
cAMP responsive element binding protein 3 like 1 |
protein |
Q96BA8 |
| CREB3L2 |
cAMP responsive element binding protein 3 like 2 |
protein |
Q70SY1 |
| CREB3L3 |
cAMP responsive element binding protein 3 like 3 |
protein |
Q68CJ9 |
| CREB3L4 |
cAMP responsive element binding protein 3 like 4 |
protein |
Q8TEY5 |
| CREB5 |
cAMP responsive element binding protein 5 |
protein |
Q02930 |
| CxI |
NADH dehydrodenase |
protein |
E9PQ53 |
| CxII |
succinate dehydrogenase flavoprotein |
protein |
P31040 |
| CxIII |
ubiquinol-cytochrome c reductase |
protein |
P47985 |
| CxIV |
cytochrome c oxidase subunit 3 |
protein |
P00414 |
| CYBA |
cytochrome b-245 alpha chain |
protein |
P13498 |
| CYBB |
cytochrome b-245 beta chain |
protein |
P04839 |
| CYCS |
cytochrome C |
protein |
P99999 |
| CytC |
Cytochrome c |
small molecule |
CHEMBL2028166 |
| DAB1 |
disabled homolog 1 |
protein |
O75553 |
| DAT |
sulute carrier family 6 member 3(neurotransmitter transporter,dopamine) |
protein |
Q01959 |
| DAXX |
death domain associated protein |
protein |
Q9UER7 |
| DCTN |
dynactin |
protein |
Q14203 |
| DDC |
dopa decarboxylase |
protein |
P20711 |
| DDIT3 |
DNA damage inducible transcript 3 |
protein |
P35638 |
| DDX19B |
DEAD-box helicase 19
B |
protein |
Q9UMR2 |
| DJ1 |
parkinsonism associated deglycase |
protein |
Q99497 |
| DLG4 |
discs large MAGUK scaffold protein 4 |
protein |
P78352 |
| DNAH |
dynein axonemal heavy chain |
protein |
Q9P2D7 |
| DNAI |
dynein axonemal intermediate chain |
protein |
Q9UI46 |
| DNAL1 |
Dynein axonemal light chain 1 |
protein |
Q4LDG9 |
| DOPAL |
3,4-Dihydroxyphenylacetaldehyde |
small molecule |
CHEMBL243161 |
| Dopamine |
Dopamine |
small molecule |
CHEMBL59 |
| EGR1 |
early growth response 1 |
protein |
P18146 |
| EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
protein |
Q9NZJ5 |
| EIF2S1 |
eukaryotic translation initiation factor 2 subunit alpha |
protein |
P05198 |
| ERBB4 |
erb-b2 receptor tyrosine kinase 4 |
protein |
Q15303 |
| ERK |
mitogen-activated protein kinase |
protein |
P28482 |
| ERN1 |
serine/threonine-protein kinase/endoribonuclease IRE1 |
protein |
O75460 |
| FADD |
Fas associated death domain protein |
protein |
Q13158 |
| FAF2 |
Fas asoociated factor family member 2 |
protein |
Q96CS3 |
| FAS |
Fas cell surface death receptor |
protein |
P25445 |
| FASLG |
tumor necrosis factor ligand superfamily member 6 |
protein |
P48023 |
| Fe |
Iron |
small molecule |
CHEMBL2363058 |
| FKBP8 |
FKBP prolyl isomerase 8 |
protein |
Q14318 |
| FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
protein |
P01100 |
| FUS |
FUS RNA binding protein |
protein |
P35637 |
| FYN |
FYN proto-oncogene, Src family tyrosin kinase |
protein |
P06241 |
| GLE1 |
GLE1 RNA export mediator |
protein |
Q53GS7 |
| Glutamate |
None |
small molecule |
CHEMBL575060 |
| GNAQ |
G protein subunit alpha q |
protein |
P50148 |
| GRM1 |
glutamate metabotropic receptor 1 |
protein |
Q13255 |
| GRM5 |
glutamate metabotropic receptor 5 |
protein |
P41594 |
| GSK3B |
glycogen synathase kinase 3 beta |
protein |
P49841 |
| H2O |
Water |
small molecule |
CHEMBL1098659 |
| HAP1 |
huntingtin associated protein 1 |
protein |
P54257 |
| Hg |
Mercury |
small molecule |
CHEMBL3707388 |
| HIP1 |
Huntingtin-interacting protein 1 |
protein |
O00291 |
| HK1 |
hexokinase 1 |
protein |
P19367 |
| HSPA5 |
heat shock protein family A (Hsp70) member 5 |
protein |
P11021 |
| HTP1 |
huntingtin interacting protein 1 |
protein |
O00291 |
| HTRA2 |
HtrA serine peptidase 2 |
protein |
O43464 |
| HTT |
hungtingtin |
protein |
P42858 |
| IFT57 |
intraflagellar transport protein 57 |
protein |
Q9NWB7 |
| IL6 |
interleukin 6 |
protein |
P05231 |
| IP3 |
inositol 1,4,5-trisphosphate |
small molecule |
CHEMBL279107 |
| ITPR |
inositol 1,4,5-trisphosphate receptor |
protein |
Q14643 |
| ITPR1 |
inositol 1,4,5-triphosphate receptor type 1 |
protein |
Q14643 |
| ITPR2 |
inositol 1,4,5-triphosphate receptor type 2 |
protein |
Q14571 |
| ITPR3 |
inositol 1,4,5-triphosphate receptor type 3 |
protein |
Q14573 |
| JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
protein |
P05412 |
| KCNC1 |
potassium voltage-gated channel subfamily C member 1 |
protein |
P48547 |
| KCNC2 |
potassium voltage-gated channel subfamily C member 2 |
protein |
Q96PR1 |
| KCNC3 |
potassium voltage-gated channel subfamily C member 3 |
protein |
Q14003 |
| KCNC4 |
potassium voltage-gated channel subfamily C member 4 |
protein |
Q03721 |
| KCND1 |
potassium voltage-gated channel subfamily D member 1 |
protein |
Q9NSA2 |
| KCND2 |
potassium voltage-gated channel subfamily D member 2 |
protein |
Q9NZV8 |
| KCND3 |
potassium voltage-gated channel subfamily D member 3 |
protein |
Q9UK17 |
| KIF5 |
kinesin family member 5 |
protein |
Q12840 |
| KLC |
kinesin light chain |
protein |
Q07866 |
| L-Dopa |
Levodopa |
small molecule |
CHEMBL1009 |
| LC3A |
microtubule associated protein 1 light chain 3 alpha |
protein |
Q9H492 |
| LC3B |
microtubule associated protein 1 light chain 3 beta |
protein |
Q9GZQ8 |
| LC3B2 |
microtubule associated protein 1 light chain 3 beta 2 |
protein |
A6NCE7 |
| LC3C |
microtubule associated protein 1 light chain 3 gamma |
protein |
Q9BXW4 |
| LRRK2 |
leucine rich repeat kinase 2 |
protein |
Q5S007 |
| mAChR |
muscarinic acetylcholine receptor |
protein |
P11229 Q53XZ3 |
| Maneb |
Maneb |
small molecule |
CHEMBL491517 |
| MAOA |
monoamine oxidase A |
protein |
P21397 |
| MAOB |
monoamine oxidase B |
protein |
P27338 |
| MAP2K4 |
mitogen-activated protein kinase kinase 4 |
protein |
P45985 |
| MAP2K7 |
mitogen-activated protein kinase kinase 7 |
protein |
O14733 |
| MAP3K10 |
mitogen-activated protein kinase kinase kinase 10 |
protein |
Q02779 |
| MAP3K5 |
mitogen-activated protein kinase kinase kinase 5 |
protein |
Q99683 |
| MAP3K7 |
mitogen-activated protein kinase kinase kinase 7 |
protein |
O43318 |
| MAPK |
mitogen-activated protein kinase |
protein |
P45983 |
| MAPT |
microtubule-associated protein tau |
protein |
P10636 |
| MCU |
mitochondrial calcium uniporter |
protein |
Q8NE86 |
| MEK |
mitogen-activated protein kinase kinase |
protein |
Q02750 |
| MFN1 |
mitofusin 1 |
protein |
Q8IWA4 |
| MFN2 |
mitofusin 2 |
protein |
O95140 |
| MPP+ |
1-methyl-4-phenylpyridinium |
small molecule |
CHEMBL311617 |
| MPTP |
mitochondrial permeablity transition pore |
protein |
P21796 P12235 |
| MTOR |
mechanistic target of rapamycin kinase |
protein |
P42345 |
| NADH |
reduced nicotinamide adenine dinucleotide |
small molecule |
CHEMBL1161866 |
| NBR1 |
NBR1(next to BRCA1 gene 1 protein) autophagy cargo receptor |
protein |
Q14596 |
| NCBP1 |
nuclear cap binding protein subunit 1 |
protein |
Q09161 |
| NCF1 |
neutrophil cytosolic factor 1 |
protein |
P14598 |
| NCF2 |
neutrophil cytosolic factor 2 |
protein |
P19878 |
| NCF4 |
neutrophil cytosolic factor 4 |
protein |
Q15080 |
| NDC1 |
NDC1 transmembrane nucleoporin |
protein |
Q9BTX1 |
| NDP52 |
calcium binding and coiled-coil domain 2
|
protein |
Q13137 |
| NEP |
neprilysin |
protein |
P08473 |
| NFKB |
nuclear factor NF-kappa-B |
protein |
P19838 |
| NMDAR |
glutamate receptor ionotropic,NMDA |
protein |
Q05586 |
| NOS2 |
nitric oxide synthase 2 |
protein |
P35228 |
| NOX1 |
NADPH oxidase 1 |
protein |
Q9Y5S8 |
| NRG1 |
neuregulin 1 |
protein |
Q02297 |
| NRG2 |
neuregulin 2 |
protein |
O14511 |
| NRG3 |
neuregulin 3 |
protein |
P56975 |
| NRG4 |
neuregulin 4 |
protein |
Q8WWG1 |
| NUP107 |
nucleoporin 107 |
protein |
P57740 |
| NUP133 |
nucleoporin 133 |
protein |
Q8WUM0 |
| NUP155 |
nucleoporin 155 |
protein |
O75694 |
| NUP160 |
nucleoporin 160 |
protein |
Q12769 |
| NUP188 |
nucleoporin 188 |
protein |
Q5SRE5 |
| NUP205 |
nucleoporin 205 |
protein |
Q92621 |
| NUP210 |
nucleoporin 210 |
protein |
Q8TEM1 |
| NUP214 |
nucleoporin 214 |
protein |
P35658 |
| NUP35 |
nucleoporin 35 |
protein |
Q8NFH5 |
| NUP37 |
nucleoporin 37 |
protein |
Q8NFH4 |
| NUP43 |
nucleoporin 43 |
protein |
Q8NFH3 |
| NUP54 |
nucleoporin 54 |
protein |
Q7Z3B4 |
| NUP58 |
nucleoporin 58 |
protein |
Q9BVL2 |
| NUP62 |
nucleoporin 62 |
protein |
P37198 |
| NUP85 |
nucleoporin 85 |
protein |
Q9BW27 |
| NUP88 |
nucleoporin 88 |
protein |
Q99567 |
| NUP93 |
nucleoporin 93 |
protein |
Q8N1F7 |
| NXF1 |
nuclear RNA export factor 1 |
protein |
Q9UBU9 |
| NXT1 |
nuclear transport factor 2 like export factor 1 |
protein |
Q9UKK6 |
| NXT2 |
nuclear transport factor 2 like export factor 2 |
protein |
Q9NPJ8 |
| OPTN |
optineurin |
protein |
Q96CV9 |
| PAELR |
prosaposin receptor |
protein |
O15354 |
| PDYN |
prodynorphin |
protein |
P01213 |
| PFN1 |
profilin 1 |
protein |
P07737 |
| PI3K-alpha |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
protein |
P42336 |
| PI3K-beta |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
protein |
P42338 |
| PI3K-delta |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
protein |
O00329 |
| PI3P |
1-Phosphatidyl-1D-myo-inositol 3-phospate |
small molecule |
CHEMBL1161535 |
| PIK3C3 |
phosphatidylinositol 3-kinase catalytic subunit type 3 |
protein |
Q8NEB9 |
| PIK3R4 |
phosphoinositide-3-kinase regulatory subunit 4 |
protein |
Q99570 |
| PINK1 |
PTEN induced kinase 1 |
protein |
Q9BXM7 |
| PIP3 |
phosphatidylinositol-3,4,5-trisphosphate |
small molecule |
CHEMBL1685065 |
| PKC |
protein kinase C |
protein |
P17252 P05771 P05129 |
| PLCB1 |
phospholipase C beta 1 |
protein |
Q9NQ66 |
| PLCB2 |
phospholipase C beta 2 |
protein |
Q00722 |
| PLCB3 |
phospholipase C beta 3 |
protein |
Q01970 |
| PLCB4 |
phospholipase C beta 4 |
protein |
Q15147 |
| PLCG1 |
phosphatidylinositol phospholipase C, gamma-1 |
protein |
P19174 |
| PMAIP1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
protein |
Q13794 |
| POM121 |
POM121 transmembrane nucleoporin |
protein |
Q96HA1 |
| PPID |
peptidyl-prolyl isomerase D |
protein |
Q08752 E5KN55 |
| PQ |
paraquat |
small molecule |
CHEMBL74469 |
| PRKCD |
protein kinase C delta |
protein |
Q05655 |
| PRKCG |
protein kinase C gamma |
protein |
P05129 |
| PRKN |
parkin RBR E3 ubiquitin protein ligase |
protein |
O60260 |
| PRNP |
prion protein |
protein |
P04156 Q53YK7 |
| PRNP* |
PRNP oligomeric conformation |
protein |
P04156 |
| PSEN1 |
presenilin 1 |
protein |
P49768 |
| Q |
Ubiquinone, Coenzyme Q |
small molecule |
CHEMBL4166910 |
| QH2 |
Ubiquinol |
small molecule |
CHEMBL454801 |
| RAB1A |
Ras-related protein Rab-1A |
protein |
P62820 |
| RAC1 |
Ras-related C3 botulinum toxin substrate 1 |
protein |
P63000 |
| RAC2 |
Ras-related C3 botulinum toxin substrate 2 |
protein |
P15153 |
| RAF |
Raf proto-oncogene serine/threonine-protein kinase |
protein |
P10398 |
| RANBP2 |
RAN binding protein 2 |
protein |
P49792 |
| RAS |
GTPase Ras |
protein |
P01112 |
| RB1CC1 |
RB1 inducible coiled-coil 1 |
protein |
Q8TDY2 |
| RELN |
reelin |
protein |
P78509 |
| RHEB |
Ras homolog, mTORC1 binding |
protein |
Q15382 |
| RIPK1 |
receptor interacting serine/threoine kinase 1 |
protein |
Q13546 |
| RNA |
Ribonucleic acid |
protein |
|
| ROS |
reactive oxygen species |
small molecule |
CHEMBL1234886 |
| Rotenone |
Rotenone |
small molecule |
CHEMBL429023 |
| RPS6KB1 |
ribosomal protein S6 kinase B1 |
protein |
P23443 |
| RPS6KB2 |
ribosomal protein S6 kinase B2 |
protein |
Q9UBS0 |
| RYR1 |
ryanodine receptor 1 |
protein |
P21817 |
| RYR2 |
ryanodine receptor 2 |
protein |
Q92736 |
| RYR3 |
ryanodine receptor 3 |
protein |
Q15413 |
| SEH1L |
SEH1 like nucleoporin |
protein |
Q96EE3 |
| SIGMAR |
sigma non-opioid intracellular receptor |
protein |
Q99720 |
| SMCR8 |
guanine nucleotide exchange protein SMCR8 |
protein |
Q8TEV9 |
| SNCA |
synuclein alpha |
protein |
P37840 |
| SNCA* |
synuclein alpha mutation |
protein |
P47840 |
| SOD1 |
superoxide dismutase 1 |
protein |
P00441 |
| SPTBN2 |
spectrin beta, non-erythrocytic 2 |
protein |
O15020 |
| SQSTM1 |
sequestosome 1 |
protein |
Q13501 |
| SRSF3 |
serine and arginine rich splicing factor 3 |
protein |
P84103 |
| SRSF7 |
serine and arginine rich splicing factor 7 |
protein |
Q16629 |
| STX1A |
syntaxin 1A |
protein |
Q16623 |
| Succinate |
succinate |
small molecule |
CHEMBL576 |
| SYPH1 |
synphilin alpha interacting protein |
protein |
Q9Y6H5 |
| TAB1 |
TGF-beta activated kinase 1(MAP3K7) binding protein 1 |
protein |
Q15750 |
| TAB2 |
TGF-beta activated kinase 1(MAP3K7) binding protein 2 |
protein |
Q9NYJ8 |
| TARDBP |
TAR DNA binding protein |
protein |
Q13148 |
| TAX1BP1 |
Tax1 binding protein 1 |
protein |
Q86VP1 |
| TBK1 |
TANK binding kinase 1 |
protein |
Q9UHD2 |
| TH |
tyrosine hydroxylase |
protein |
P07101 |
| TNF |
tumor necrosis factor |
protein |
P01375 |
| TNFRSF1A |
tumor necrosis factor receptor superfamily member 1A |
protein |
P19438 |
| TOMM70 |
translocase of outer mitochondrial membrane 70 |
protein |
O94826 |
| TRADD |
tumor necrosis factor receptor type 1-associated DEATH domain protein |
protein |
Q15628 |
| TRAF2 |
TNF receptor-associated factor 2 |
protein |
Q12933 |
| TRAF5 |
TNF receptor associated factor 5 |
protein |
O00463 |
| TRAP1 |
TNF receptor-associated prottein 1 |
protein |
Q12931 |
| TRPC3 |
transient receptor potential cation channel subfamily C member 3 |
protein |
Q13507 |
| TRX1 |
thioredoxin 1 |
protein |
P10599 |
| TSC1 |
tuberous sclerosis 1 |
protein |
Q92574 |
| TSC2 |
tuberous sclerosis 2 |
protein |
P49815 |
| TUBA |
tublin alpha |
protein |
Q71U36 |
| TUBB |
tublin beta |
protein |
P07437 |
| Tyrosine |
L-Tyrosine |
small molecule |
CHEMBL925 |
| UBCH7 |
ubiquitin conjugating enzyme E2 L3 |
protein |
P68036 |
| UBCH8 |
ubiquitin/ISG15 conjugating enzyme E2 L6 |
protein |
O14933 |
| UBQLN2 |
ubiquilin 2 |
protein |
Q9UHD9 |
| UCHL1 |
ubiquitin carboxyl-terminal hydrolase L1 |
protein |
P09936 |
| ULK1 |
unc-51 like autophagy activating kinase 1 |
protein |
O75385 |
| VAPB |
vesicle-associated membrane protein-associated protein B |
protein |
O95292 |
| VCP |
transitional endoplasmic reticulum ATPase/valosin containing protein |
protein |
P55072 |
| VLDLR |
very low density lipoprotein receptor |
protein |
P98155 |
| VMAT1 |
solute carrier family 18 member A1 |
protein |
P54219 |
| VMAT2 |
solute carrier family 18 member A2 |
protein |
Q05940 |
| WDR41 |
WD repeat-containing protein 41 |
protein |
Q9HAD4 |
| WIPI1 |
WD repeat domain, phosphoinositide interacting 1 |
protein |
Q5MNZ9 |
| WIPI2 |
WD repeat domain, phosphoinositide interacting 2 |
protein |
Q9Y4P8 |
| XBP1 |
X-box binding protein 1 |
protein |
P17861 |
| ZFYVE1 |
zinc finger FYVE-type containing 1 |
protein |
Q9HBF4 |
| Zn |
Zinc |
small molecule |
CHEMBL1201279 |