RiceNetDB is currently the most comprehensive regulatory database on Oryza Sativa based on genome annotation. It was displayed in three levels: GEM, PPIs and GRNs to facilitate biomolecular regulatory analysis and gene-metabolite mapping.
| General Information | |
|---|---|
| Protein ID | LOC_Os04g55500 View Network |
| Names | Crossover junction endonuclease EME1 (Essential meiotic endonuclease 1) (OsEME1) |
| Function | Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks, nicked Holliday junctions and also intact Holliday junctions with a reduced efficiency. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. Plays a role in DNA repair and in genotoxic stress-induced homologous recombination (HR) in somatic cells. Mediates a subset of meiotic recombination events that are insensitive to crossover interference (By similarity). |
| Attributes | Length: 651 Status: Complete Existence: Evidence at transcript level Molecular Weight: 71743.1 pI: 7.9987 Subcellular Location (predicted): Nucleus |
| Gene Model | LOC_Os04g55500.1 |
| Database Links | |
|---|---|
| UniprotKB | Q0J9J6 |
| Ensembl | LOC_Os04g55500.1 |
| Refseq | NP_001054077.1 |
| EMBL | AL606635 AP008210 CM000141 AK066786 |
| KEGG | osa:4337213 dosa:Os04t0648700-01 |