General Information
Protein IDLOC_Os10g28200        View Network
NamesGDP-mannose 3,5-epimerase 1 (GDP-Man 3,5-epimerase 1) (OsGME-1)
FunctionCatalyzes a reversible epimerization of GDP-D-mannose that precedes the committed step in the biosynthesis of vitamin C (L-ascorbate), resulting in the hydrolysis of the highly energetic glycosyl-pyrophosphoryl linkage. Able to catalyze 2 distinct epimerization reactions and can release both GDP-L-galactose and GDP-L-gulose from GDP-mannose.
AttributesLength: 379
Status: Complete
Existence: Evidence at protein level
Molecular Weight: 42778.4
pI: 5.9867
Subcellular Location (adjusted): Cytosol  
Gene ModelLOC_Os10g28200.1  LOC_Os10g28200.2  
Enzyme1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase
5.1.3.18  GDP-mannose 3,5-epimerase
Reactions
OSR1319  OSR1051  OSR1060  
Pathways
KEGG Pathwayrn00053  rn00520  rn01110  rn01100  
Metacyc PathwayPWY-2582  PWY-882  PWY4FS-12  PWY4FS-13  PWY-5115  
Database Links
UniprotKBA3C4S4
EnsemblLOC_Os10g28200.1  
RefseqNP_001064609.1  
EMBLAB193582  AC016780  DP000086  DP000086  AP008216  CM000147  
KEGGosa:4348636  dosa:Os10t0417600-01