General Information
Protein IDLOC_Os10g41590        View Network
NamesE3 ubiquitin-protein ligase BRE1-like 2
FunctionE3 ubiquitin-protein ligase that monoubiquitinates H2B to form H2BK143ub1. H2BK143ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and maybe H3K79me. It thereby plays a central role in histone code and gene regulation. Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBC2/RAD6 (By similarity).
AttributesLength: 845
Status: Complete
Existence: Evidence at transcript level
Molecular Weight: 96497.8
pI: 4.6059
Subcellular Location (adjusted): Nucleus    
Gene ModelLOC_Os10g41590.1  LOC_Os10g41590.2  
Enzyme6.3.2.19  ubiquitin---protein ligase
Reactions
OSR2941  OSR2942  OSR2943  OSR2966  
Protein-Protein Interaction ( Show in Viewer )
LOC_Os11g34300  LOC_Os04g04320   LOC_Os08g42600   LOC_Os07g07240   LOC_Os04g46450   
Database Links
UniprotKBQ336R3
EnsemblLOC_Os10g41590.1  
RefseqNP_001065421.1  
EMBLDP000086  DP000086  AC087599  AP008216  
KEGGosa:4349420  dosa:Os10t0565600-01