RiceNetDB is currently the most comprehensive regulatory database on Oryza Sativa based on genome annotation. It was displayed in three levels: GEM, PPIs and GRNs to facilitate biomolecular regulatory analysis and gene-metabolite mapping.
| General Information | |
|---|---|
| Protein ID | LOC_Os04g46450 View Network |
| Names | E3 ubiquitin-protein ligase BRE1-like 1 |
| Function | E3 ubiquitin-protein ligase that monoubiquitinates H2B to form H2BK143ub1. H2BK143ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and maybe H3K79me. It thereby plays a central role in histone code and gene regulation. Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBC2/RAD6 (By similarity). |
| Attributes | Length: 885 Status: Complete Existence: Evidence at transcript level Molecular Weight: 100373 pI: 7.9007 Subcellular Location (experiment): Nucleus |
| Gene Model | LOC_Os04g46450.1 |
| Enzyme | 3.3.1.1 adenosylhomocysteinase |
| Reactions | |
|---|---|
| OSR0776 | |
| Pathways | |
|---|---|
| KEGG Pathway | rn00270 rn01100 |
| Metacyc Pathway | PWY-5041 METHIONINE-DEG1-PWY |
| Reference | |
|---|---|
| PubMed | 20171579 |
| Database Links | |
|---|---|
| UniprotKB | Q7XU27 |
| Ensembl | LOC_Os04g46450.1 |
| Refseq | NP_001053489.1 |
| EMBL | AL663000 AP008210 |
| KEGG | osa:4336589 dosa:Os04t0550400-01 |