| Function | Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Plays an essential role in meiotic and somatic DNA repair, but is dispensable for DNA replication and homologous recombination. Is essential for normal progression through meiosis in pollen mother cells. Is involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. |
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