RiceNetDB is currently the most comprehensive regulatory database on Oryza Sativa based on genome annotation. It was displayed in three levels: GEM, PPIs and GRNs to facilitate biomolecular regulatory analysis and gene-metabolite mapping.
| General Information | |
|---|---|
| Protein ID | LOC_Os07g34570 View Network |
| Names | Os07g0529600 protein (Thiamine biosynthetic enzyme) (cDNA clone:J013116J24, full insert sequence) |
| Function | Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance (By similarity). |
| Attributes | Length: 356 Status: Complete Existence: Evidence at transcript level Molecular Weight: 37224.8 pI: 5.406 Subcellular Location (adjusted): Chloroplast |
| Gene Model | LOC_Os07g34570.1 LOC_Os07g34570.2 |
| Reference | |
|---|---|
| PubMed | 16514565 |
| Database Links | |
|---|---|
| UniprotKB | Q7XXS4 |
| Ensembl | LOC_Os07g34570.1 |
| Refseq | NP_001059841.1 |
| EMBL | AB110170 AP008213 AK099918 |
| KEGG | osa:4343443 dosa:Os07t0529600-01 |