General Information
Protein IDLOC_Os12g09000        View Network
NamesProbable thiamine biosynthetic bifunctional enzyme, chloroplastic [Includes: Thiamine-phosphate synthase (TP synthase) (TPS) (Thiamine-phosphate pyrophosphorylase) (TMP pyrophosphorylase) (TMP-PPase); Hydroxymethylpyrimidine kinase (HMP kinase) ]
FunctionEssential for thiamine biosynthesis. Bifunctional enzyme that catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP and condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity).
AttributesLength: 549
Status: Complete
Existence: Evidence at transcript level
Molecular Weight: 57804.3
pI: 7.8811
Subcellular Location (adjusted): Chloroplast  
Gene ModelLOC_Os12g09000.1  LOC_Os12g09000.2  
Enzyme2.5.1.3  thiamine-phosphate diphosphorylase
2.7.4.7  phosphomethylpyrimidine kinase
Reactions
OSR0878  OSR1196  
Protein-Protein Interaction ( Show in Viewer )
LOC_Os12g19590  LOC_Os12g21890  LOC_Os12g09000  LOC_Os02g48840   LOC_Os02g52510   LOC_Os04g51370   
LOC_Os08g39140   LOC_Os07g41180   LOC_Os01g01312   LOC_Os03g49730   LOC_Os03g18410   LOC_Os07g02350   
LOC_Os05g05860   LOC_Os07g33850   LOC_Os01g27160   LOC_Os01g23630   LOC_Os04g22240   LOC_Os03g15700   
LOC_Os01g48280   LOC_Os02g37880   LOC_Os02g30624   LOC_Os04g22860   LOC_Os07g25440   LOC_Os08g10470   
LOC_Os10g32920   LOC_Os07g43980   LOC_Os01g16650   LOC_Os12g09000   LOC_Os01g40610   LOC_Os02g56960   
LOC_Os07g29360   LOC_Os02g54910   LOC_Os02g51180   LOC_Os05g06350   LOC_Os06g04580   LOC_Os09g10720   
LOC_Os03g04590   
Pathways
KEGG Pathwayrn00730  rn01100  
Metacyc PathwayTHISYN-PWY  
Database Links
UniprotKBQ2QWK9
EnsemblLOC_Os12g09000.1  
RefseqNP_001066343.2  
EMBLDP000011  AP008218  CM000149  AK066087  
KEGGosa:4351707  dosa:Os12t0192500-02