RiceNetDB is currently the most comprehensive regulatory database on Oryza Sativa based on genome annotation. It was displayed in three levels: GEM, PPIs and GRNs to facilitate biomolecular regulatory analysis and gene-metabolite mapping.
| General Information | |
|---|---|
| Protein ID | LOC_Os09g34970 View Network |
| Names | Os09g0521500 protein (Putative hASNA-I) (cDNA clone:J023080G12, full insert sequence) |
| Function | ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). |
| Attributes | Length: 362 Status: Complete Existence: Evidence at transcript level Molecular Weight: 40410.4 pI: 4.6578 Subcellular Location (predicted): Cytosol Chloroplast |
| Gene Model | LOC_Os09g34970.1 |
| Enzyme | 3.6.3.16 arsenite-transporting ATPase |
| Database Links | |
|---|---|
| UniprotKB | Q64MA8 |
| Ensembl | LOC_Os09g34970.1 |
| Refseq | NP_001063707.1 |
| EMBL | AP006859 AP008215 AK071023 CM000142 |
| KEGG | osa:4347615 dosa:Os09t0521500-01 |