RiceNetDB is currently the most comprehensive regulatory database on Oryza Sativa based on genome annotation. It was displayed in three levels: GEM, PPIs and GRNs to facilitate biomolecular regulatory analysis and gene-metabolite mapping.
| General Information | |
|---|---|
| Protein ID | LOC_Os07g08729 View Network |
| Names | ATP-dependent DNA helicase 2 subunit KU70 (OsKU70) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) |
| Function | Single stranded DNA-dependent ATP-dependent helicase. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair. When associated with KU70, binds to double-stranded telomeric and non-telomeric DNA sequences, but not to single-stranded DNA (By similarity). Required for the maintenance of chromosome stability and normal developmental growth. Plays a role in maintaining telomere length. Acts as a negative regulator in telomere homeostasis. |
| Attributes | Length: 625 Status: Complete Existence: Evidence at protein level Molecular Weight: 70056.5 pI: 5.299 Subcellular Location (adjusted): Nucleus |
| Gene Model | LOC_Os07g08729.1 |
| Enzyme | 3.6.3.1 phospholipid-translocating ATPase 3.6.1.3 adenosinetriphosphatase 3.6.4.- Hydrolases acting on acid anhydrides to facilitate cellular and subcellular movement 3.6.1.5 apyrase |
| Reactions | |
|---|---|
| OSR0792 | |
| Pathways | |
|---|---|
| KEGG Pathway | rn00230 rn00680 |
| Reference | |
|---|---|
| PubMed | 19923234 |
| Database Links | |
|---|---|
| UniprotKB | Q7F1M0 |
| Ensembl | LOC_Os07g08729.1 |
| Refseq | NP_001059061.1 |
| EMBL | AP003861 AP003861 AP008213 CM000144 CM000144 AK102066 |
| KEGG | osa:4342584 dosa:Os07t0184900-01 |